Aspergillus niger P450s

 

David Nelson

 

August 7, 2009

 

156 sequences

 

>CYP51F1  Aspergillus niger

         estExt_fgenesh1_pm.C_150008|Aspni1

         84% to CYP51F1

MGLLAVVLDSLCERCSNTSVLVVLGFGLLSLLAVSVIFNILRQLFFKNPNEPPLVFHWFPFIGSTISYGMDPYKFFFDCR

AKYGDIFTFILLGKKTTVYLGTRGNDFILNGKLRDVCAEEVYSPLTTPVFGRNVVYDCPNAKLMEQKKFVKFGLTSDALR

SYVRLITGEVENFVEHSAAFKGSSGVFDVCKTIAEITIYTASRSLQGKEVRSRFDSTFAELYHDLDMGFAPINFMLPWAP

LPHNRKRDAAQKKMTETYMEIIKERRNGGNKKDSEDMVWNLMSCIYKDGTPVPDEEIAHMMIALLMAGQHSSSSTASWIV

LHLARNPQIMEELYAEQIRVLGSDLPPLTYDNLQKLDLHAKVIKETLRIHAPIHSIIRAVKNPMPVDGTPYVIPTSHNVL

SSPGVTARSEEYFPNPLKWDPHRWDETIAASAEEEDQIDYGYGLVSKGTNSPYLPFGAGRHRCIGEQFAYVQLGAITAAL

VRLFKFRNLPNVKDIPETDYSSLFSKPAGKSIIQFEKRATTIKS*

 

>CYP51F2  Aspergillus niger CBS 513.88

         XM_001394187.1, CAK40582.1

         80% to CYP51F2 Aspergillus fumigatus

MALLAVAGVYAFAALLVAIVLNVTRQLLFRNEKEPPVVFHWIPF

LGSTISYGMDPYTFFFSCRKKYGDIFTFVLLGQKTTVYLGVQGNDFILNGKLKDVSAE

EVYSPLTTPVFGSDVVYDCPNSKLMEQKKFIKFGLTQAALESHVQLIEKETLDYLRDS

PRFNGASGVIDIPAAMAEITIYTAARALQGEEVRKKLTAEFAELYHDLDKGFSPINFM

LPWAPLPHNQKRDAAHARMREIYTDIINERRKNPDEEKSDMIWNLMHCTYKSGQPVPD

KEIAHMMITLLMAGQHSSSSISSWIMLRLASEPQVLEELYQEQLASLSNRNGVFEPLQ

YQDLDKLPFLQSVIKETLRIHSSIHSIMRKVKNPLPVPGTSYIIPEDHVLLASPGVTA

LSDEYFPNATRWDPHRWENQPDKEEDGEMVDYGYGSVSKGTASPYLPFGAGRHRCIGE

KFAYVNLGVIIATIVRHLKLFNVDGRKGVPGTDYSTLFSGPMKPAIVGWERRFPDHSK

GSLN

 

>CYP52G6 Aspergillus niger

fgenesh1_pg.C_scaffold_15000225|Aspni1

57% to CYP52G2

MGLATLLLVLVGLTFILRIVSEKWRHRQNAKRLGCQPAPMAPSKDPLAIGDILEIIQADKDKVVPELLESRTNIMRDNNA

GRYVSTFRLKRGLGENLLTFDPENLQAMLAKQFKDFSVGGERLGCMGPLLGKGIFINDGAEWSHSRTMLRPQFTREQISD

LGLEERHVQNAMRAIPAAGSNGWTEVDIQSIYFRLTLDSATELLFGESCYSQLAAMGDAEDRMASGGKVTDFGKNFDRAQ

WYMAQRLRLPRMKFLYDNKEFRTCCQEVHRFVDECVAKALHDHKKKKQQQQLLEEGASEHYIFVHAMAETTKDPIELRSQ

LLNVLLAGRDTTAALLSWTTLLLSRHPEVFHKLREAIIADFGTYENPQNITFATLKACTYLQQVMNETLRLFPPLPTNAR

YATKDTSLPRGGGPDGQSPVYIKKGQAVLYNVHMLHRREDVWGKDAKEFKPERWEARRSGWEYLPFNGGPRICIGQQFAL

TEAGYVLVRMLQRFDGIEDVHADQRIRWGLTLVSAPGDTVTVRLHEASR*

 

>CYP52G7 Aspergillus niger

e_gw1.7.657.1|Aspni1

67% to CYP52G3

MSTLLFVATASPILYLLYVLLSRWQHAQNARKWNCGSVPSYPGDLLGINTLKEALAMDKARQVPTVTRRRVETMSARENR

YTTTFQFRQLGTDVISTCDPKNVQALLATQFKDFELGQSRRNALHWLLGRGIFTADGDHWSRSRALLRPQFTRDQISDLD

LEERHVQVAMKAMPVDATGWTPATDIQTIFFRLTMDTATEFLFGESVQSQAAALSNGAIPQDDFPAQFDRGQWYSAQRAR

FEKLYWIINNKESRAINKAVHAYVDRFVTAALNSDPEKKPTGHYVFLHGLAEATRDPVELRSQLLNILLAGRDTTASLLS

WCVLFLARHPAYFSSLRATILAEFGSYSSPRDITFANLKSCRPLQNFLNEVLRLYPIVPGNRRTAVRNTTLPTGGGPAGT

DPVYVKKGQPVFYSTYVMHRRPDLWGADADEFRPDRWNERKAGWEYLPFNGGPRICIGQQFALTETGYVLVRLLQRFDVI

EGVGKTKEGEINMQMSLTNAPGDNVTVRLHEDASN*

 

>CYP52H4 Aspergillus niger

estExt_GeneWisePlus.C_80246|Aspni1

73% to CYP52H2

MLAPAIVFLGAIYLTFRILSSLHQAYHHRKKAKALGCQPPNSVDTGILGITGFYRIAKAAREKRWVEYIAEHYQTSGPTF

RQRALGGLMVTNTVEPENIKALLATQFQDFGLGTRHREFYPLLGNGIFTLDGAGWSHARGMLRPQFTRDQVADLDLMDGH

ITKMMDLIPKDGSTFDIQRLFFLLTIDSATHFLFGESVGSMRTSAESSLLEKSTVGNAQGFAEAFNRAQEYLAARSRAMA

FYWLVNPKEFREANQLVHEVVDHYVRLALEAKRHPEKKEPGRYIFAEALAGDTDDPRVIRDNMLNILLAGRDTTASLLSS

AFFYLARHPNVWTRLRQTIVDEFGDAQHPKGTITHARLKDTPYLRYFLNEVLRLLPPVPLNFRVAAKDTSLPLGGGPDGK

APIYVRKGELVSYSVYAMHRRTDLYGPDAHAFRPERWEENSKRGWEYLPFNGGPRICLGQQYALTEASYTMVKLLQRYNR

IENADPDMVEPIINSSLTLSHDRGVHIRLFSS*

 

>CYP52P1 Aspergillus niger

gw1.4.1682.1|Aspni1

46% to CYP52K1

WPLGLDLLVQAFHYDRRQQILKFFLGVVAESGTTFEQNLLFSRGVDTIDPQNIQALLSTQYADFGLGLRPPTFCPLLGSG

IFTQDGAQWRHSRERLRPQFMTNRFTNFEQIRSAVDNLISSISDDNAVNLQPLFFRLTFETTLFLLFGQHLPSLQLEGIK

NQESDFANAFNLGQEYLAKRGRLGGFYWLLDGRDFREACKTCHEFVDRAVQKALDLTTKKTPGTKTEPYIFIDAFIEETR

NPEVLRDQCLNILLAGRDTTACCLTWTLRLLVQHPPVLSKLRAEISDTVGIGPRSPAPTIIQVKSLPYLSLVIKEVLRLY

PSVPVNSRAATKTTTLPTGGGPTGTAPILVRKGEAVGYCVYAMHRRRDIYGADADKFRPERWENDALKDVGWGYLPFNGG

PRVCLGREFALLEVGYTIMRLLQTFEVIEQAE

 

>CYP52Q1 Aspergillus niger

e_gw1.11.186.1|Aspni1

45% to CYP52H3, 41% to CYP52P1

MPWSAASLSLATFFSALVALQLYWIVSRSYRSRKLSKQWNCEPVCRYPSGILGYKVVLRAKTAAQEGQVGSTIQGVHLQY

GNTLKVNLVGHDVVATCEPENIQAVLASQFSSFGLSEWRYPQYRPLLGRGIFTSDGTAWEHSRKLLRPQFTKNQIPSIEW

FDSHSENLMRSLPPDGHAFDIQPLAFRLALDSATGYLFGESINSLVKPDSNQTGVAETSGSGNEGFAAAFDYAQDILFRR

TLALSYYWLINPSDFRKSTRVVHKFVDYYVDKAIEYRSNIGNYKTGHEQKGEEYCFLHALAAETQDREFLRDQLVNVLLA

SRDDVASVLASTFYLLARDTRAWWKLKQEITDAVDRHASNITLKEIQSLPYLRGVLYEVLRLFPPVPVNARVAHHDTTIP

VGGGPDGRSPVFIPKGQMVAYSVWCLHRRRDLWGADAESFRPERWEGYNPPAWEFVPFNGGPRACLGQQFAMILISQQVF

RLVQHLDSIESAQPGPDMGLNPPLRQTLTMCHEHGVHLRVKRMRI*

 

>CYP53A1 Aspergillus niger X52521

MLALLLSPYGAYLGLALLVLYYLLPYLKRAHLRDIPAPGLAAFT

NFWLLLQTRRGHRFVVVDNAHKKYGKLVRIAPRHTSIADDGAIQAVYGHGNGFLKSDF

YDAFVSIHRGLFNTRDRAEHTRKRKTVSHTFSMKSIGQFEQYIHGNIELFVKQWNRMA

DTQRNPKTGFASLDALNWFNYLAFDIIGDLAFGAPFGMLDKGKDFAEMRKTPDSPPSY

VQAVEVLNRRGEVSATLGCYPALKPFAKYLPDSFFRDGIQAVEDLAGIAVARVNERLR

PEVMANNTRVDLLARLMEGKDSNGEKLGRAELTAEALTQLIAGSDTTSNTSCAILYWC

MRTPGVIEKLHKALDEAIPQDVDVPTHAMVKDIPYLQWVIWETMRIHSTSAMGLPREI

PAGNPPVTISGHTFYPGDVVSVPSYTIHRSKEIWGPDAEQFVPERWDPARLTPRQKAA

FIPFSTGPRACVGRNVAEMELLVICGTVFRLFEFEMQQEGPMETREGFLRKPLGLQVG

MKRRQPGSA

 

>CYP55A12P Aspergillus niger

gw1.11.1089.1|Aspni1

48% to CYP55A5v1 aa 53-257, this is a pseudogene

LKSIPVSRKNLFDGSCP*MVIKLKETYNILVDPRLLK (0)

VRQRDRYPEISAGAKKRAENSPTFINMDPSVHGHQRFIARLNS* (2)

SFKPEYIKSCEGFNKHTVRRYLERLIKTKADQQSVDRVENFTLSIPSH ()

IIYNLLGIPDKDFIYLTNCNAT*TNSGNTAGAAQSANE (2)

KYLKYFDHLLDERIANPGDNIISSLAKEQLQQGNLER*DII

 

>CYP55C1 Aspergillus niger

fgenesh1_pm.C_scaffold_5000072|Aspni1

40% to CYP55A1, 40% to CYP55B1

MYPFARPPKSYDPPAELAELRHQGPTERVQLFDGRPAWIVTRDKEVREMLSSDKFSNDRYNRDGYPEIHSGTKKDGVRPT

FVHMDDPKHARHRAMTESFFTPEATEAVKPQVQEVVDSLIDSIKERGCNNGPIDLVKELATVVNPKVILLSILKVSEKEA

NELIQSSSALGGTSGSASESGHTDLHEYISQLIDARIEKPRRPQDDLLSKLVVDEYRQANLDRDDLINLVYMIFVAGNSA

IQSSIVLGVITLLQHQDQLEELKENPGLAGRVVEEILRYHTPSALNSRRVTTTDITLGGKKIKSGSGVIGSVRSANRDER

VYPDADKFSIHRQVDPHQNLAFGHGPHNCQGQWLSRMELQAIFSSLFRKLPNLRLAIEPSELEYTSPTQNVGVLRLPVVF*

 

>CYP58F2 Aspergillus niger

fgenesh1_pm.C_scaffold_7000005|Aspni1

60% to CYP58F1

MFVYAWLGIGLLAYYVFRSVYLLYFHPLHKIPGPKLAAITYGYEFYYNVIKGGKFVWEIERLHKIYGTVIRINPDEVHIN

DPDYYEEIYTSRARRREKDPVQIAQFDLDGAVFSSITPETHRQRRSHLDKFFSKQAISNIEYLIHDSLDKIIKTYKEAYQ

SNNVVNLDAGFAGLTADVIYQYAFGFNPGNLDAERFNESVRDASNAFFRGIHILNFFPFIKVIMGLMPLGLLRLKNQTSV

QQDEXXXXXXXXX

KVSNSRGAILDAIAGPHMPAHMRTPVRLMNEGLALAIAGTETTARSLSVGTYHLLTRDDIRLKLREELKTVMPTPD

TRVGRTELEKLPYLSGVINESMRLSTGVSSRMPRVAPTEALVYKEHIIPPGNDPSSHVFILMDPNIFPDPHDFDPERWIR

AAEKGERLDRYLVNFSKGSRICLGMQLAYAELFIVIATLMRMFDMELADTPRETIEFARDFGTPYPEKGNLCVKARITIL

VQQ*

 

>CYP58L1 Aspergillus niger

e_gw1.12.119.1|Aspni1

49% to CYP58D1, 49% to e_gw1.8.187.1

MYTILLPLLVVICVSVRAIYRIYFHPLSKIPGSKLAAATHLHEFYHDVIRGGKFIWEVEKMHRIYGPIVRINPREVHIAD

PSMYDEIYAGCGRKREKDPCMVSAYASSYAALATVDHDLHRARRAPLNRFFSKKAVIELSGVVQQKVSFLAWHLERVNAE

QAVLVLSTAFTALTGDIITHYLYGKDNGYLRERDLVKRNIVWDILAEGTSACHLFRFFPFIPTLTKALPIQLMRLVRPEL

SNVYAMQEQIARQSDKALASERGAKRRTIYLALSDPSVPARERSVARLRDESFIVLLGGTESTAATLTFATYHLLRNKDM

YFKLRQELQQVMPEPTSEADWAQLERLPYLTAVINEALRLGAAALRPARVAPTETLYYKGYEIPPGTPVSTISYFVHRNP

AIFPDPESFNPERWIQAANRGDNLTRYLVPFTRGSRICIGMNLAYAELYMTLAAIVRRFDLELCETHPKDMEFTREMVVQ

RPEKGVWTLKVRVVGINET*

 

>CYP58M1 Aspergillus niger

e_gw1.8.187.1|Aspni1

51% to CYP58K1

MALDTSHIWLALVGIASFYVLRSIYRLYFHPLSGIPGPKLAAVTHLYEFYYDVVIHGRFLFQIEKMHQQYGPIVRINPRE

VHISDPSFYDEIYASSTRKRERDPLAYGAFALPYS MIGTMGHEHHRFRRNILNDFFSKRSVLAISPFIEERVEKLRGRFE

GFYRDQSVVNLSDAFAALTSDVITYYCYGKRWGFIEDKDFRSDVHGGNEENTGLAHFNRFFPIVPETMRKIPLHLMALCL

PGKAGMLQFQGSILSTISENTHDKASEKEDRTIFKRLTDPNLPVAERSQRRIEDEVFTLLGAGTETTASTLMIMTYYVSR

DRSIRDKLRSELKQVLPTPTSTATWPELEKLPYLTAVVNESLRLSYGLIMRLPRVAPTETLKYKDYVLPPGTPMSTSTWF

VHRDPSLFPEPDRFDPERWIKAAEEGVNLTRYIVSFMRGSRACIGMNLAYIELYLTIAHVVRRFNFDVEITSPESMRITR

DRIVPGTEKGLMRVYAKVTDMMED*

 

>CYP58N1 Aspergillus niger

e_gw1.9.613.1|Aspni1

42% to CYP58C1, 39% to e_gw1.8.187.1

MDYYKALIVLIVYLCLRTIYRLALHPLRGIPGPKLAASTSLYEFYYDAIKGGKYIWEVERMHRQYGKSFTEAILSSLNLT

RGKGPIVRISPREVHIKDPYFYDEIYTSSSIRKRDKDSKLVASFCAPTASFSTVDHNLHRSRRAVISHLFTRKAVVSHEF

LIQDNVGKLASRLESIHKKGSVFSLKIAAAALISDVLAQYMYGTSTHYLDDPTFRSESVASATELASKIHILRHIPVIAT

IFQLLPLALLRPFRLLSDFCDFRLWLRKQSQDALQGKGGSTVRRGPVFDALLRANVPAEEKTLQRLEDESFTLFSAGSET

VSQALSVIFFHLLKNAEFIKTLRKELKQVMPMPTDLATWSELEKLPFLTAVITEALRLSGTSGRLPRVSPTEPLIYGKYI

IPAGTPVGQSNYFAHRDPAMYPNPNAFDPYRWIHAEDENTNPKPFYAPFSKGSRQCIGINLAYATLYLTVATLIRRFDME

ISDSTEDELRTARDFLIPFPEKG

 

>CYP58-un1 Aspergillus niger

gw1.19.191.1|Aspni1

43% to CYP58J1 pseudogene fragment C-term, 52% to CYP58M1

TPMGSSSDFIRRDPDNFPSLNNFTSTRWLMENGITIHSTRYLVSFSKGSRGRIEM ()

NLPYFELYLTVAYLVR

 

>CYP59C2 Aspergillus niger

e_gw1.2.1390.1|Aspni1

63% to CYP59C1

MAFINLLLTICLPVVVSVVAYGLHALYQHRSKINRLRKQGIAMPPGWNWLTGHMFVLSEYLNRLPPDANVVLATQELAWE

YTDTEIFLLDVWPMSPAQYIVFYPEAASQATTKFNLPKTVIHDRFMRPITGGPSMISVGNAEWKPWRSIFNPGFSAGSMQ

DLLPEVIKSVSVFCDKLREKADSGEMFALDDLTTRLTMDVILKVTLDADVDHQNSDNIIATALGQITKWHSFWDPRVRAN

PLRPLVQGYYGRVADKWIRKALADRFSEMKQVKRDASIRSKRAKSILTLALEAYLENKNEEISEATELDDDFAKHVTYQI

RLFLFAGNDTTSSSIAYVYHLLSKHPEALTQVREEHDRIFGPDPSAAVQLLCEQPSLLNKCPYTMAVIKETLRLYTPAST

MRQGIDGLSLTDRHGNRYPLADDLSVSVLHQAVHLNPRVWPRAREFLPERWLVDADHELYPDPAAYRPFEQGPRNCIGQT

LVYNEMRTVLVMTARTFEIKPAYDEWDATKAKQKGWFDQIAESVGFQNKKPKLLHGERAYQSEKAGTHPVDGYPCRVSLV

A*

 

>CYP59D3 Aspergillus niger

e_gw1.12.714.1|Aspni1

63% to CYP59D2

MPPWDPIFGHLRIMPGLAKKCPSDALQSQTFAVLSMEYPGLQNGFYIDVWPFMCPMFVCTTPPLAVQACQTYSLAKPTEL

LAPFINPMAGGDNFFTTNGAAWKRDRDLFNHAFSMAAVLGHVDYILEEAEIYVEILREHAKKGDTFSMDDLACNYMMDVV

GNVALNTRFNYQTGHNPIAAAMRSTIDLECGREGENNPLRRWNIHRLYRQWRNSQIMDHHIGLELEKRYQEYLQQNQSTK

PRGKSIMDIVIAEYMKHRPASQTHTATLDPEFKAWAIIQIRLFLFVGHDSTAVTIIYCLYLLSKYPDALVKIRAEHEQIF

GPKTTSVATQIKEHPEKTNQMPYTTAVIKEALRLFPPANGLRFGRPGVSLTDTHSSDGRTFPVDDCAVWIVHTAIQRNPG

YWPHAHKFVPDRWLVEPGHELYPPTGGWRPFERGARDCVGQNMALLAIKISLAMVVREFDFDSQYEEWDRMNPASGAVRT

MFGERVYMVAKGAAHPAQGYPCKVRLAA*

 

>CYP61A1 Aspergillus niger

estExt_GeneWisePlus.C_12230|Aspni1

84% to CYP61A1

MASVNGSFVSPSADAVVSPRLFEPTGLVASVLEGFTVWKALLTLFVAAVIYDQFRYLWLKGSIVGPAWKLPFMGPFLQSV

NPKFHEYKAKWDSGELSCVSVFHKFVVIASTRDMSRKIFNSPTYVKPCVVDVAHKLLGADNWVFLDGKDHVEFRKGLNGL

FTRQALSFYLPRMEEVYNEYYARFLRISKENNFKPTPWMPEFRELMCAVSCRTFVGHYITEEAIQKIADDYYMITAALEL

VNFPFILPYTKAWYGKKAADMVLAEFSNCAAKSKARMAAGGEISCIMDAWVKAQQDSAKYREKIAQGIAVEASDKPAQVL

RDFTDYEIAQTVFTFLFASQDATSAASTWLFQLMADRPDVLDKVREENLSVRNGDIKAPLTMELLDQLPYTRAVVKETLR

YRPPVIMVPYLVKKDFPITENVTVSKGSMIIPSVWPACHDEEAYPNADSFDPDRWITGTAEQQTKNWLVFGTGPHYCLGQ

TYAQLNLMAMIGKASMEMDWEHTPTPESEDIKVFATIFPQDDCLLAFRPRP*

 

>CYP61A7 Aspergillus niger

estExt_fgenesh1_pm.C_40133|Aspni1

74% to CYP61A5

MEANSHSFASPLASVRASNLPIPSQFETVVDAVSNASPWTIAFTILAVLVAYDQIIYLINKGNIVGPAFKIPFIGPFLES

VNPKFEEYYAKWTSGPLSCVSVFHKFVVIASTRDLARKVFNSPTYVKPCVVDVAHKLLGKENFVFMDGKPHVDFRKGLNG

LFTKKALQSYLPGQEDVYNQYFERFLGITQKAGGKPVPFMPEFRELMCAVSLRTFCGYYISDEAVKKISDDYYLITEAME

LVNFPIILPFTKAWYGKKASDMVMAEFCQASAKSKVCMAAGKEPTCIMDAWVKNILASKQWVEAEAKGQLAENMEKPSPL

LRDFADWEIAQTVLAFLFASQDATSSAATWLFQTMAQRPDVLDRVREENYKVRNGNVHAEVDMDQLESMTYTRAVVRELL

RYRPPVIMVPYVAKKPFPITDSYTVPKGAMVIPTTYLALRDEEVYEKPDEFDPERYYTGDAEEKGKNNYLVFGTGPHVCI

GQHYAQLNLVLLIGKASLLLDWKHHATPLSEEIKVFATIFPKDDCPLTFNKRKW*

 

>CYP62C3 Aspergillus niger

estExt_fgenesh1_pg.C_150110|Aspni1

67% to CYP62C2

MERQVALCAATAVAIWVLQIAYKLLRSPLRHIPGPLYTRVTRLPLKFSIVTGRRIYFIHNLHQKYGPVVRIAPDEVSVSS

LPEFKEIHRVGSAFLKTPWYQKFAWDRNPGLFTMRDPKEHAARRKLFARVFSKSDLRRTWEPEVKDKVQLAVSQIRGELL

RDGISDILKWWTFLATDVSGHLMFGESFDMLQYGK

VSYQSDYPCMRGSANCQ

KNEYINVLESTMMGSGINVELPIVGLLG

RYVPLASCQAMFRPSDYLTEYGRRAVSNSRTNSNSTRNIFTGMLNESEKASSMLSEEDVVIEAGNLIVAGSDTTAVTLTY

LVWAVLSQPTLQHDLEEEVSALDPNYNEAALEELPLLNAVITETLRLYGAAPGSLPRSVPNGGATFCGYHVPQGATVSTQ

SYTIHRDEELYPDPETFDATRWLGGHGNGSDVAKQALSPFGYGTRVCLGVHLAWMELRLAATEFFRECRGVRLASDTTRE

SMKPENYFLIAPSGHR

YSSSSGRKRMSGEEGGWFYGDSGDPVIRFGMMDRTGDQCQMDLQNDWVDAEPKQGCPCFRAVGP

TAASAEATWNHEKKTITRSSPPTTRGLAGLLNSPPPDLNKPEQQVTYRGSGRTGGCCQACCKGAALVRHEANPTSTLSPN

VAPLRGVSLPVGI*

 

>CYP65T6 Aspergillus niger

e_gw1.4.330.1|Aspni1

65% to CYP65T4

MPTILAIVVISYIVYTVCAAIWNIYLHPLHRIPGPKLWLAFPILRYISFMRGVLDRDMRTYHNRYGGAVRFSPNEVSFIT

TQAWKDIYGHGHRQLPKVPGSMNNPMDIISANDSDHTRFRKAISHAFSAKGLQAQEPFIMEYVDKLINKLHSMAKSQVAV

DMAKWYNLTTFDLIGDLAFGESFGGLDSTEYHYWVSTIFEFIKAIAFARFKDNYPMMFQVLERFLPKHLLEAKRRQDEYS

WNTVQKRLHHQRDRGQADFMQSMLRHRGEKDGLTDEELAANASILVIAGSETTATLLSGLTYWLLQHPKEMEKVKFEVRS

VMKTEEDIDVNNATAKLPYMLACIDEAFRMYPPVSGGLQRYVPDTPTEISGYLLPPKTNVSVHQSAAYRSPLNFYRPEEF

IPERWLPQSKNDPSSPFYHDNRDVLQPFSVGPRNCIGRNLAYAEMRVILARVLWNFDIELCEESRDWHDQKSYNLWAKPP

LMCRLKARVH*

 

>CYP65T7 Aspergillus niger

fgenesh1_pg.C_scaffold_3000290|Aspni1

68% to CYP65T4

MLDPLILAIAPGIYFLYSILSIIHALYLHPLRHIPGPKSWIILPLFRHISAVRGRLDADIHRFHEKYGPVVRVTHNEVSF

NTAEAWNRIHGYGHSELPKVSSSGANPRDIVSANAADHSRFRKALSPAFSAKGLQAQEPLINSYVDKLISRLKDIAESQL

PADMVKWYNLTTFDIIGDLAFGEPFGGLESSQYHYWVATIFQFLKLLPFLKLRDAYPTIFKLIALAMPKTLLNARERQRA

HTRITVQKRLDNASKYDRGDFMDSMLRNSGTKDGLTHEELVANANILIIAGSETTATILCGVTYWLLKSPDALAKVTTEV

RSIMKSETDISVSSVAAKLPYMQACIDEAFRMYPPVPTGLTRMTIEPTLISGYEIPPGTKVFVHPIAAYHSPRNFHAPER

NLPERWLPEAKTDPASPFFSDNREVLQPFSIGPRNCIGRNLAFAEMRVIIARLLWNFDIEICEESKDWSDQKTFTLWEKP

PLMCKLSLRN*

 

>CYP65U2 Aspergillus niger

e_gw1.3.403.1|Aspni1

61% to CYP65U1

MAINALSIAISLLVIVCIAFPTWQLFLLQNQLLKLFAQYPISRIVYNVFFSPLSHLPGPISWSATRLPFTRALLRGTIVH

DFERLHRKYGPVVRTAPDEVSFASGDAWTDIYASRPDDRQFLKDPLWWRRQPGQPDTLLSAIHPAKHSRMRKLLAPAFTP

RALRVQEAVLQRYASLLVDRIKDQVSVAGTDGAVIDMGPWFNFTTFDIFGDLGFGESFNCLQHSQYHPWIVLLFGSVKAA

SFIAAARYYPPLEALLMKCIPRSLHEKSQRHYRQIINKIDRRLSWELQRPDIMSHLMDENGQVALPRGELNSTFMILTTT

GSETTATVLTGILTYLVNQPEVLGRLIGEIRGRFGSSQDISLSEAADLPYLTAVIQEGLRLCPPVPWMLPRQVPPGGSTV

CGTWLPGGTAVSLQAYTLNRDPSRFHAASSFLPERWLPDASSNPNSNFYQDDRHAVQPFSMGPRSCLGQHLAWAEMRLIL

TKLLVNFDFEAVEGKQLRWEELRTFLLVEKRPLEVRVRLA

 

>CYP65V4 Aspergillus niger

e_gw1.11.216.1|Aspni1

70% to CYP65V3P

MTLPDIFYHPPADDHDSTHHAHNNRSNATERERGVGGTCFRGNGPSLVYNICDAQSNLAAQVTIYYATQIIYNVFFHPLS

RFPGPISHAISRLPYCYYALIGTLPFHMLDLHNQYGDIVRIAPDELAFSHPNAWKDIMGHKNGEEELGKADWFYRPLPEA

RHIVNEERDQHKGLRRAMAHGFSEKAMREQEPLIRKYTDLLLERLREQSKSGQSVAISDWYNFTTFDIIGDLAFGEAFGC

LENAKYDYWIKTIFESGRLGIILQSISFYPILKSLLLLLVPKSLQEAQQKHKALTTTKMLRRLAILEDRPDLINSLLKKK

EDLALTMDHLIANAEILIIGGSETTASLLSGVTYLLLQNPDAYQNLRDEVRSTFRKQDEINLISVNKLTYMLACLDEGLR

MYPPIANGLPRMCPRGGCTVLGHYIPENTYVSMHQWALYHREKHFTDPESYHPERFMGSPQFANDRRDVLQPFHVGPRNC

LGRNLAYSEMRLILALIIFNFDMVISEDCDDWIQQKNFLMWQKRPLKVYLKPVPRDNP*

 

>CYP65W2 Aspergillus niger

fgenesh1_pg.C_scaffold_14000165|Aspni1

53% to CYP65W1

MALIQVVGSDSMFWLGAVALTSLLAWVILHVCYNAFLHPLRQYPGPRLWAATRLPWCWYQAHGRLNQKLLELHLRYGRIV

RVAPNELSYNSEEAWRAIYGLRSDEMGKDPVFSLRTPTGVQNILTADRQTHTRQRRLLSHAFSEKALREQEGIIQGYVDQ

LMKQLAARANDGPQNMVDWFTFTAYDLIRDLSFGERFHCLDTAEYDPFVRSIQAISKELTFIQMLAYYKLLSLRQLFMSK

AFSGARAQNMQRVIETVNRRVDRNTDRKDFLHYILAAMETEKGMSRAEMNVNAFSFSIAGSESSATALSAFTYYTLSRVS

VYDRLIAEIRGTFDAYEQIDISSTAQLSYLNAVLQETLRIYPPVAVTLPRVVPVNGTVIDGDFVPAGVTVGVNHFACYHD

PRNFHRPQEFLPERWLPECQAQGPFSKDCQKSCQPFSFGPRNCLGKNLAWAEMRLIAAKLLFLFDMEIDETSKGWTDGQK

VLGFWVKPPLFVRLMQRGC*

 

>CYP65AG2 Aspergillus niger

e_gw1.3.1457.1|Aspni1

57% to CYP65AG1

MDGPIPKLLVSVSRTLIFKYARPLHHPQSSSQLPIASPGPNRILEKVIIVTIFRYFYRLFLHPLRSYPGPRLAAISHLPY

ISWCVRGILHSKIRTLHEQYGEVVRIRPNSLTYCAPQAWEEIYGHRKKGQRTFTKDPQFYIASSGQFTSMINANEEDHIR

QKRLLTHAFSEKALRDQESLIMAYIDVFITRLAEYAASESPRATNIVHWLNYLTFDIVGDLSFGEPFGCLDRSTYHPWVE

TIFKSIKTGAFLRALAIYPLANIAFNKLKPKRLIRKRLEHYQLSRDRVHKRLHVSNTISRPDFLKYILKNNSFQEGAGMA

VAEIELNAALLIQAGSETVATALSACCFYLGRNPPKLEATVREVRTTFADSGHISFSATSALLYLNAVIKEALRLYPPAP

GIGPRLVPEGGAVINDQFVPAGVSVSVAQFSTFRSPASFIEPDSFLPERWLPNSDSRYLTDNKNALQPFSYGPRACIGKN

LAYAEMRTILSKILWHFDISLQPGSDSWDQSLSYIVWENQPLNVVLRPAMNS

 

>CYP65AK1 Aspergillus niger

fgenesh1_pg.C_scaffold_9000016|Aspni1

42% to CYP65R1, 34% to fgenesh1_pg.C_scaffold_5000711

MIHENLHEALQGRYLILTAGLLFFSLVGKCFYELYINPLCKIAGPKLAAVTRLVYMYHNLMGDEHTWMRNLHLVYGDTVR

ISPDQVSYSSAEAWRDIYGHASATKKSTEKDKRFFGTTLNGTPDVIRAPAADHSRFRRNFSHAFSDKALREQQPLIAHYA

DMLIDKLREIVQADPKARIEMVMMYNLTTFDIMGDLTFGDPLNLLKGTGNVAWVTSIFSSVKINSLRRIARYYPWCSYFL

NSLLPRSLKQRQASHYQSCKDRVDWRVDQSLDRPDIWGLVMAQKESLRLSREEMYANSQLFMVAGTETTATALSGLTYQL

LLNPDKLEKITNEVRDAFEQSSDIDMLRLAQLKYLNMCIDEGLRMYPPVPTGMPRLTPKEGMEICGEYIPGDTAVSVHHW

ATYRNPRNFTRPDEFLPERWGNDPQFASDNKAACQPFSFGPRNCLGKNLAYHEMRLILAKVLYHYDLRLAPESVGWEKQN

TWTLWQKNRLMVQLTPRA*

 

>CYP65AL1 Aspergillus niger

fgenesh1_pg.C_scaffold_5000711|Aspni1

42% to CYP65Z2, 43% to CYP65Z3

MEVGLFQTMVANANGLILAVLVSLGCWVIYTLYFHPLARIPGPKWWIISRIPYFRSITTGQFIHSVRALHERYGPVVRLA

ANEVSFTDPQAWQDIYGHHGGERAFPRNPVWYQPALNGVHHILSASNSDHARIRHLLSHAFSERALKSQEPMIQVFFNLL

IERLRPLADGRQAININDWLQYTTFDITGELEFGESFGCLEKGEYHPWIKVLLSNFRKIILFGASQLIPGLRFLVGLTIP

KAVMQQRQQHFSYTVEKVSRRLARGNDPMRPDFLTYINRYNEDEKKGMSRAEIDSTFNVLVIAGSETTSTCMTATLHCLL

RNPATLQRLQTEIRSTFAHDSDITFDSTIPLPYLNAVIEESLRLCPPAPTMLPRVTPAAGAYVCGYWLPGGTAVEISQYA

MSRSHANYGDPDRFIPERWLVDEKPNLHPHDARAHRPFSFGPRNCLGRSLAWMEIRCVLCKLLWNFNLRMESPDYEWNEQ

GTYVMWDKKQMLISLTPVKR*

 

>CYP65AM1 Aspergillus niger

estExt_Genewise1.C_31719|Aspni1

45% to CYP65AF1, top 28 hits are CYP65 or CYP60

MAINTLVMDVAMRVEWLATPRVILGIGAGWLFIYIISKVVYALCLDPLRHIPGPRLNAVSMIPYARHLLAGTTVQNSVSL

HQQYGEVVRIAPNEVSLICGETAFPDIYGFRTGKMKGHLNMSKDPVWYVTPSNGAPSILQANDEDHSRGRRVLAHAFSDK

ALMGQEPLVQRYVDQLIDRLKEVTSANDEPVDMVKWYNWTTFDVIADLLFGEPFGCLQDLSTHQYVALLFQSLKSLRMIY

ILAYYPWLRFLGNLIVDKGLIQKRKEYATWVSTQVTKRINTATPRPDFMSHILANNNNRGVKLTRAEIDSNATLMTTAGS

ETTATLLSGATYLLLTHPRVLRTLQDEIHSEFPTYESITLEAVAKRTPYLNAVISEALRFFPPIPVGFIRRVPKGGETVS

GYWIPEGTILSVSHYAAYHSERNFRDPDSWVPERWLGDERYVNDKRAAFQPFSFGPRSCLGRNLAYAEMRLILAKMVWSF

EMELDEGLSRDWLQRCRVMRLWQKPELEVRVRPR

 

>CYP65AN1 Aspergillus niger

gw1.16.109.1|Aspni1

36% to CYP65Z1 top 26 hits are to CYP65 or CYP60

YSILCVFYNIFFHPLKHYPGPRIMASSRLPIFFLVLIGRSVNILEKLHAKYGPVVRVAPDELSYTAASAWKDIYSSSAAW

PLAIPRNMVFFRAMAGEYGFHSLVTANNQDHARLRRLYSRAFSKQALAAQEPLIIQHIDNLIKKLYAEIDHTAKPVDINL

YLNLALFDMINDLQFGEPLNLLDDTTHRAFARASLIIVPSAAVIQALADFPLARIILKPILRELFRMRRLYFSTTDERLE

KRLASNSYRADIVQFLTDAKSDNISLQEIQANAPLMNIAGSGTSAVALSGLIAHLLLAPHILKDLQSEIRSKFHTTSNIT

MKNMVDMPLLDACIKEVLRVFPAVPVTPGRLVPSPGVTIAGKWVAGGTRVYVTPLAAFHSTDNFHDPETFAPQRWYNTKE

ESSFTCKDVKGAYKPFSVGPYNCIGQYMAHYVVSLFICNLLLHFDLEIATDPKTWLSNQRAWIIWHNPPLNV

 

>CYP65AP1 Aspergillus niger

gw1.10.1058.1|Aspni1

40% to CYP65AF1, 60% to fgenesh1_pg.C_scaffold_1001144

Top 27 hits are CYP65 or CYP60 (CYP5118 also in this set, may need name change = 41% to CYP65Z2)

FPILLALKRLYFHPLSRYNGPLLWALTRVPYMLAFRNGQLAHKIKAFHEVYGETVRVAPNEVSFINPDTVKDIYQRRPSG

GGFKSLPKDPIRQAPPRPGQPISILDAGDADHTRLRKAYAAAFSSQALSAQEPLVASYVDKMITQMQCQSKLIAQSVDLQ

EWISFCTFDIVCKLSFGEDFGCLDNQRYHEWVGQLVHSLKAKVQLASCRFYPWLFNYLVKRLPKSAGILMAQHQATTKEK

VKRRLQQLESDAKSSGAAGVIRPDFLAHLVQQSRQEISEGEMVVNAATLIVAGSHTLQTAITGILFHLLQNPTVLNRVTS

EVRGEFPSTSQINVSTLLRLPMLEAAIKEGIRLTSPVPLGLTRLVPIGGHTINGEYFPEGTVVSYMQWAANVSPQNYTDP

QAFHLERWLKSRQPSSSSRDDFFEKDQRHATQPFLQGPRDCIGQNLARMEIVLILGKLLYHFDLQPEGGLGHWEDQETYA

VWVKTPLPVKLRVRQTD

 

>CYP65AP2 Aspergillus niger

fgenesh1_pg.C_scaffold_1001144|Aspni1

40% to CYP65Z2, 60% to gw1.10.1058.1

MLAFRSGRLAHDIKRFHDIYGDTVRVGPDEVSFLDPDCIKDIYSRRPNNPHYKALPKDPIRQKPPQPGQPGDILDVEDDD

HSRIRKAYAPAFSTQALNAQKPLVTSYVCKMVAQLKSRANSTDPSRRIVDLQRWVTYCTFDIICSLSFGEDFGCLDNDSY

HEWVGMVVNSVKGKVRIAAFRFYPWLFNYLVKSLPKSAQLMVKRHQAMTNEKVQKRLHTAVDRPDFFSYRLKSKNELTEP

EMEINAATFIFAGSHTLQSSLTGILFHLLKNPEALARVAEEVRSSFPDEGDLDANKLSKLPLLDAAIKEGIRLTAPVPLG

IPRLVPRGGHTVCGQYFPEGSKVAYNSWAAGVSPRNFADPTKFHLERWLNPDEGRFANDRRSAVQPFLQGPRDCIGQNLA

RLEMSLVIGYLIYHFDFVLPNGREALGEWEDQETYAVWMKSPLMVELVAR*

 

>CYP65AQ1 Aspergillus niger

gw1.10.1062.1|Aspni1

37% to CYP65Z2 top 36 hits are CYP65 or CYP5118A1 (needs name change)

PTTLVIYNLFLHPLARYPGPTLWRAFRFPFLLANIGGQLPHRIHDFHAQYGDIVRVAPDELSFVDPRAWRDIYTSDREFV

RPHQYKDQPPGKTAANLIACSEAEHARLRKNLAPGFSEKFAALQEPILQKYIDTLFAKLDAKIASSEGDSASKGADVDLV

EWINYLAFDVIGDLTWGSSFGCLEGLRYHPWVQTVSQFKAAIVVGMIKFYPPLYRLLMAITPADALKPVMEMWKVTDERV

AERVATTAPSTTTRPDFVGIMMASGAMTQEEMEVNSMLIIAAGSESITTVITGVINYLLREQDQRSLRELVNLLHNTFPT

EEKITATRLKSVSYLDAVLMEGMRLCPTIPDAMRRQVPRGGAKVAGQFVPEGMIVSIPPLASYRAPGNFSSPTEFVPRRW

LGEDKQFDLSKQKKAFNPFSLGSHNCPGQNLAWIELRLILARLLWRYDLAAVDVPAWEKQGIWWFWDKKPLVVRIK

 

>CYP65AR1 Aspergillus niger

gw1.11.201.1|Aspni1

36% to CYP65AH1, top 21 hits are CYP65

MVTYNLFIHPLKEVPGPRMLAASRIPVTYASLKGIQTQWLHNLHLKYGPVLRVAPNELSFIDPQAWKDIYSSSPTEPQSM

RRGSDFFRYLEDDDNRPSILAANEIDHPRIRRAYVPAFSRRALARQESILAKYGDALVERLSGIEGQITNIRNMFHYTLF

DIVGHLHFGEELGVLRTGAHKSWVHSQHRLVRAATLLSALAEFSWINLLFRSTIPWMSKWLRKAYFKPSNDLIDRRLQLQ

SDEPDLIGLAFRNSRSLSLTEKDIRANAHIMMTGGAETTTALMTALTAYLLQHPECLARLKNDIRTAFHDKSQVSLESVS

NLAYLDACIKEALRLYPSVPGALHRATPAGGARIAGRWVSGNTRVYIPIFAATHSPTHFWSPDKFIPDRWLDGADDPYQK

DNKTAFHPFSTGPRGCIGQDMAYAMTKIVFCKFVTEFDCELAVNESSPWLAGHRSWTTWEVPPLMVRVSRCK

 

>CYP68D3 Aspergillus niger

e_gw1.6.1239.1|Aspni1

60% to CYP68D1

MPVPVLVSLALGLAFLLLQSFRYKDPALNPKKPFELTSTRVKQEYFSNARRLLWDWFTTHSNTPVLLHTDTGKVTILPPS

MANEIRNDDRLSFSRWTFEAFHGNLPGFDGFREGSQDSGIVQAVIGNDLTKYLNKVTEPLANETSVAVRELLTDNEEWHT

IQLRTVMVALISRISSRVFLGEKLCRNEEWLRVTQDYTTDGFLAAEELRMWPAAIRPIVHWFLPRCRKLRAQVKVARKVM

GPILEERRQFKKHLHAKGKQSQGFDDAIEWFEKAAKGRPYDPVSAQLILSVAAIHTTSDLTSQTMTHLVQNPEILEPLRK

EIVDTLQQHGWKKTALYNMKLLDSVIRESQRLKPINNASMRRVALKEVKLSDGTVIPKNGMLAVSAHKLWDDDTYENAAA

WDGYRFYKMREDPERQTKAQLVTTAPENLAFGHGKHACPGRFFAANEVKIALIYLLLRYDWKLLEGTVPKIRYGGFSMAV

DPSLKMEVKRRREEMGI*

 

>CYP68S1 Aspergillus niger

e_gw1.4.292.1|Aspni1

51% to CYP68L2

MELKVDVKEHGNPLSLGTSIFLLSLVLLFVFRWGDTPASQNGLPLINAKRRFEIVDLLAKKRFITNAQELLKAGLEKASV

FNIVTENGVMMVLDPKYADEIRNSKTLSLRKTLIEDMHVNVPGFEQQMQALEDDEIFQTTLKTKLTRNLEDLNEILSQEA

TVALQEHWTNNPEWHEIPLSRSMLKIIAQLSSRVFLGDKICHNPKWLRISVDYSIDLFQATFELRIYPRFLRPLASRFQP

SCRRLRADIREARSIIEPVIEERQLAKAIAKQEGRDPERHEDTIEWLEEVANGRQYNPVSAQLLLSSAAVHTSSDMLTQV

LYDLDGRQELIEALREEIRSVFENGWERSSLAKLRLMDSVLKESQRLKPISSVSMRRMAEAPVTLSDGTLIPKDCKVIVP

CLRQWDEKYYPDPETFIPDRFLKLRNEPGYEHTAAFANSSPNHLGFGLGRHACPGRFFAANEIKLALCHILMKYEFRVVG

KKPEKVVFGTMLAADPNGVIAVRRRK

 

>CYP68T1 Aspergillus niger

e_gw1.3.1460.1|Aspni1

51% to CYP68L2, 42% to e_gw1.4.292.1

MFAANIISYLAKLVPPRWIWAPILAAVFFWLLSAPSLKTSLPVINQRRRFEIGSLGSLKRFFKDAHGLVRAGLSQGSAFY

LYSEFGPKIVLASKYADDFRSHHALSLLDAVAEEYHAHIRGFDPFNRDPAIIIDMVRMKLTPHLGDLARPLSEETGRALG

ELFTDDPDWHDLELKPNMLDLISRLTSRVFLGEKLYRNPDWHRVTAGYVVHTFMSALFLRMFPRCTRPFVANLLPFCRKM

RKELQEAKDIITPVVEERRTAKQDAIRQGKEPERYVDAMQWMEECAKGRPYDPTLAQISLTLATIHTTSDLLTQTLFYLA

ERDEIIVALRNEVITVLQGDGWSKSTFNNLKLMDSILKESQRLKPHNMDVILSDGTVLPKGSISVLTTEAMRDPTIYPDP

EIFDAYRFLKLRETPGYETMVQAVSTTPQHLAFGLGKHACPGRFFAIALLKIILCHILLEYDFKIADGWSPTVRKYGFIW

QADPVAKVSVRRRKEEFTIL*

 

>CYP503A2 Aspergillus niger

e_gw1.4.275.1|Aspni1

54% to CYP503A1

MNKAETPSDSFSELHLIAAIGLSPALVGLLLGIYSLWYLVGPALKQHNTSNQPPIVGCRSRWEPTWLVRLRFIRGSRKII

GEGYERFKDTMFQVRRVGTDVLLVSSKYMDEIRTLTRDATGSVPPLVQDYPGEYTHGMPFLRSDLQNRVLQQKLTPNLPS

LVPVMVEELEFAMRMEMPECAADDWTTVDIMPILSRIITRITSRIFLGPKEGRNEEWLVATVEYTRNFFLTGMALRFFPR

FLRPLVAPLLPSYHHLWQNVATSRRIVGEIVRERREIEAAKPADYTKPADILQWMMDAATGQEAEPGDLAQRMLILSVTS

IHTTTLTMTQAIYDLCAHPQYLEPLRAEVEDVLCTDGGWGKLTVNHLRKMDSLLKESQRFNPVFLLTFNRILPKSITLSN

GVSIPVGSRIAVPSNAMLNDPSRVPGDAPTSFDAFRYSRLREEPENAQRHLFVMTDHNNLAFGYGKFACPGRFYAANEMK

MMLAHMLICYDMRFPDGRGRPRNFTIDSDMYPDPATRLLIRKR

 

>CYP503C1 Aspergillus niger

e_gw1.10.655.1|Aspni1

42% to CYP503B1

MVNDTELWTLVTTAHPLPVESIHWTYTLLFLAVGAYCCSIFWSQIFGYKLPIFGTKSPWEPVIISNFRFFHHAEQVLQQG

YNECKNRIFQFRRADTDMLVLPPKYVDEIRRLPNHIASPTLAHVHNLMGSRINMHIILRNNLHFRTLQVKLTPNLNSITL

PMQEEVNYAIEKDFTKSEDEWVTIKPYHTILDLVSRVSARIFLGQPLCRNPQWLELSTQFTENVFVSLVFLRLFPMWTHG

LLTWFMPSSYRGSAYIRQAKKLLVPEINRRRKLASEGIEEPAENKHNLLSWMMEIATPEESDPASLAHLEVVLSLAAIHT

SQMNAVHVLYDLLVHPEYLEPIRDEIRTTILENGPWMTWEKSAFSKLRKLDSFMRESQRVNPPTLLSMHRVLLQEVTLSD

STRLPKGAHISMAVNAIQNDPEVTTNPETFDGFRYYKLRQREGEAHLHQFSTTQDRILNFGHGANACPGRFFAALEIKII

LVRLLMDFEWKLKEPGKRPENLHAHEFIFPNPDAEILMRRRPASECLQL*

 

>CYP504A15 Aspergillus niger

fgenesh1_pm.C_scaffold_7000252|Aspni1

88% to CYP504A8

MAVQTILIAAAAVIYFLVRYMNRTDVPKIKGIPEIPGVPLFGNLLQLGTQHAVVARKWAKSFGPVFQVRMGNKRVVFANS

FDSVRQLWIKDQSALISRPTFHTFHSVVSSSQGFTIGTSPWDESCKRRRKAAATALNRPAVQSYMPIIDLECTASIKELF

KDSQNGARDINPKAYFQRFALNTSLTLNYGFRIEGNVNDELLHEIVNVERGVANFRSTSNNWQDYIPLLRIFPKQNREAQ

EFRERRDKYLSYLLEILKDRIAKGTDKPCITGNILKDPEAKLNEAEIKSICVTMVSAGLDTVPGNLVMGIAYLASEDGQR

IQQKAYDEIMKVYPNGDAWEKCLVEEKVPYVSALVRETLRFWTVIPICLPRESTKDIEYNGATIPAGTTFFMNAWAADYD

EDHFKMPEKFIPERYLDVGEGSGTPHYGYGAGSRMCAGSHLANRELFTAYVRLITAFTMHPSRDLADRPILDALECNEIP

TGLTTEPKPFKVGFTPRDPTKLQQWIAESDERTKDL*

 

>CYP504B7 Aspergillus niger

estExt_fgenesh1_pm.C_30542|Aspni1

85% to CYP504B5

MAIAAVLSFLQQSILESPLQSLAATAFIVPVLYIIINEFIRASARVSGLKGPRGLPLIGNLAQIRKNAAEQYRIWSRTHG

PVYQIQLGNIPVVVVNSAAAAKVLFGHNAQALSSRPEFYTFHKIVSNTAGTTIGTSPYSESLKRRRKGAASALNRPSVES

YISHLDVESRSFVDELYRYGNGGETPVDPMPMIQRLSLSLSLTLNWGVRVASQEEDLFAEITHVEEEISKFRSTTGNLQD

YIPLLRLNPFNSNSKVAKEMRDRRDRYLTALNRDLDDRMKKGIHKPCIQANVILDKEAKLNSEELISISLTMLSGGLDTV

TTLVAWSIGLLSQRPDIQEKAAKAIRDMYGHDQPLCDPMDDQRCAYVAALVRECLRYFTVLRLALPRTSIRDVVYNGTVI

PKGTVFFLNSWACNMDPEVWSDPEEFRPERWLEQPDAPLFTYGMGYRMCAGSLLANRELYLVFMRTLNGFRIEPLGETDW

HPVRGNSDPTSLVAIPKKYKVRFVPRDEKALAKALGR*

 

>CYP504E5 Aspergillus niger

gw1.9.669.1|Aspni1

84% to CYP504E1 aa 219-331

ERWWRQYGHSVFQIKLGNTRAVVFNSFEDCRTVLLGHQNAIIDRPKLYTFHGVISSTQGFTIGSSPWDDSCKRKRKAAGT

ALGRPALRNYHPMFDLESYCIVRDLFRDSKNGQPGSVTGASADPTRSYIKRGAPPPDIALPHLHQLSXQSTLFTPKMGSL

LTQDMMSVKGRVALVTGGSSGIGRMIAQPSYQGLVTNGAKAYIVALPGDPIDQTVQDLNACGIESGGSAEGYACDLSSKD

SIYQLAKSISQKETKLDMLISNAGIRRDPPIACNVLTATLAELQESMWSSRESDWADTFRINTTAHYFLSVAFLPLLAAA

AD

 

>CYP504E6 Aspergillus niger

e_gw1.112.2.1|Aspni1

84% to CYP504E2 aa 279-590

ISLLRSASENLQDYIPILRYAPNNEKTARSKELRERRDAYLNLLLNKVRDMIKKGTDKPCISAAILKDEETKLSGVEVSS

ICLSLVSGGFETIPGTLTSVIGSLSTPEGQIWQDRAYEDIKRYYADPGDAWLSSIHEEKVPYVNAIVKEAGRYYTVSSMS

LPRKTATEVNWNGAIIPPKTMILINAQAGNHDVDHFGPDAGKFDPERWLKSVDPPSEKEIQGLPHLSFGAGSRACSGQVI

AIRLLYTALVRILSSYKIVASEDQPPNTDYVEYNQFKTALVAIPRDFKVRLIPRDDVLTRQCLDAAELRTKE

 

>CYP505A15 Aspergillus niger

fgenesh1_pm.C_scaffold_7000162|Aspni1

72% to CYP505A13

MGSVKPVPIPGPKGVPFLGNVYDIDQEMPVRSFELMADQYGPIYRLTTFGLSRVVVSTQELVDEVCNEERFAKSVDGGLG

QLRNLLHDGLFTARYPGEENWALAHRVLIPAFGPLSIRGMFDEMQDIANQLVMKWARQGPETPIVVTEDFTRLTLDSIAL

CAMGTRFNSFYHDSMHPFVEAMVGGMQVASYRAQRPSFLNQLPTSENNAFWNDISYMRNLAKELIEDRRKHPSDKKDLLN

ALILGRDPQSGKGLSDESIIDNMITFLIAGHETTSGMLSFVFYYLLKNAHAYKKAQEEVDRVIGRRKITVDDLSKLPYIN

AVMREALRLNPPASVMRVHAHPTKNKEDPVTLGNGRYVLNKDEPITVLLPKLHRDPKVYGADAEEFKPERMLDENFNSLP

RNSWKPFGNGMRGCIGRPFAWQEGLLAIALLLQNFNFQLDDPSYDLRIKQTLTIKPKDFKMRATLRHGLDPITLEPALNS

GSVPRESSTVASRERKKDAALSEGDMKPMHIFFGSNTGTCEALARRLADDAVAWGFSAKVNSLDSATENVPKGDPVVFIA

ASYEGQPADNAAHFFEWLSAANDNELEGINYAVFGCGHHDWTATFYRIPKAINELVKEHGGNRLCDIGLVDTAIADMFTD

FDNWSESALWPAISSKFGSKSQGQAGKKASSGLQVELSSEKRVTTLGLQLQEGYVIENKLLTAPDVSAKRLVRIKLPSDM

TYQCGDYLAVLPVNPTSIVRRAMRRFKLPWDAFLTVRKSSQTQNGPSAIPTDTPISAFALLSSYVELSQPASKRDLTALA

DAAVADEESQAELRYMANSPSRFNEEVVTKRLSLLDILDRYPSIGLPLGDFLAMLPPMRVRQYSISSSPLTDPTECSITV

SVLNAPSLSGTDEPYMGVASTYLSILQADERIHIAVRPSHSGFKPPADLNTPMIMACAGSGLGPFRGFVMDRAEKILSRS

DSITEKPAPAILYVGCRTKGKDDIHAEELAEWSRQGIVDVRWAYSRPSDGSVAQHIQDRITSDRDEVVSLFEQGARIYVC

GSAEVGKAVRQAFKNIYVDVKQERRRVALETKQEEVPSEVNDEDVEKFFDDLKASMRYATDVFT*

 

>CYP505B2 Aspergillus niger

fgenesh1_pg.C_scaffold_1000650|Aspni1

62% to CYP505B1

MSDAKIIPIPGPRPLPLLGNILDFDLDNLTQSLDRLSKAHGPIYALTFGSSTEIMVTSRRIAEELCDETRFCKLVAGGLE

KMKPVVGDGLFTAQSDDPKWAIAHRILMPLFGTMKIREMFNDMKDICEQMCLKWARLGESFPLDVCKNFTTLTLDTISLC

TIDYRFNSFYRDGKEDPFVEAVIAVMTDAFTQSNLPDFVNNWFRHKAMADFHDHAQNLRRRTEEIIQERRRSPVERNDLL

NAMLTAVDPKTGERLSDQSVVDNLLTFLIAGHETTSSLLSFCFYYLLENPDVLQKARDEVDQVIGDGPMMVEHLQKLPYI

ESILRETLRLRDPGPGFYLKPLKDDILDGKYYVKKDQPIFIVFDSVHRDPETYGSDANNFRPSRMSQENFEKLPPCAWKP

FGNGVRSCIGRPFAWQQSLLAVAMILQNFDLIKDETYKLKYHVTMTVRPVGFHMKVRLRRQRRATDFAQKLHAPVASQVP

LINHHQSIRPNTVEGSRITILHGSNAGSCEALALRLAADAGEYGFTRSKIEPLGSAVGKLPTDNPVIIITASYNGEPADE

ASDFVAWLKTAGRDELSGVSFSVFGCGHRDWASTYFAVPKLLDAEMERAGGRRIAPLGTADSATSDLFTDLEKWSVTHLF

PGLGNTEHIRRDAQGVKVSSSCQVMLSDPPRVTLRKGFVPTSITESRCLSQPGVPEKRHLELRLPDGFTYQPGDHLYRVL

SRFHLEGDMLLTLTRSQSLGLPVNTPISASDLFGAYVELRQIASPKGILALADSTPDSCTQTILRDLAGDLFKVEIQDKY

VSVLDLLERFPTINPSIGLFLSLLTPMRPRAYSFSSSPNEKPGYGTLTYTVVGSARSTGNRIELLSLFTPSCDPLHSTTP

LYSGLSPLVMVAAGTGLAPFRGFIQERRFRQLAGKKVGPALLFYGCRGRDLDDMYRDEMDGYEKEGVVSIHRAYSRVKGA

DFRYIDSAIARFLDHVVSLWASGGVVRVCGGKKMSNSVFEVLGPALLERDRLDGKTDVTDVAEWKRDLPRGRYVEEIFL*

 

>CYP505E1 Aspergillus niger

fgenesh1_pg.C_scaffold_3000014|Aspni1

77% to CYP505E2, 48% to CYP505C3

revised 3/23/2009

MRDAERIPGPT (1)

PLPVVGNLFDIDLEHVLQSVIGLANKY (1)

GPLFQITINGEKQIFATSQALVDELCDESRFHKAVASGLEN

LRMLAHDGLFTAYHGERGWGIAHRILVPAFGPLRIQSMFDDMGDLAQQLCLKW

ARQGASNSINITDDFTRLTLDTIALCTMDFRLNSFYNNDTMHPFVESMLYVLREADVQSALPGIANSVRIMAHRRMLKNIEA

MRTIARDIIHDRRKKENPADDLLNTLLNGRDPVTGEGMSDESIIDNVITFLVAGHETTSGLLSFTFYYLVQHPDILKKAQ

KEVDETVGQAQISVQHLAELPYIDAILKESLRMMPTAPGFTVTPKKAETLGGKWLLNAGQPINVLLPACLRDRSIFGPNA

DEFSPERMLAENFSKLPPNSWKPFGNGERSCIGRAFAWQEAQLVVAMILQNFDLVPDDPSYTLRIKETLTIKPDGFRVRA

TLRHRQTATGLFQHTLSARNDTSLASSSAHFIKKSEDQAPAGGRPICFFYGSNSGTCKALAHRLASDLMPYGFTDQKLAV

LDTAVDNLPRDQPVIILTTTYDGQPTDDAKKFVAWLESGKVPALQGISYAVFGCGHHDWTQTFYRIPTLIDELMHKAGAT

RLAPRGTANAAVSDLFSDLEAWEETSLLPALRETFLLSSSSDLEPRNLHQLQISLSKPRRIDLHKDLMEARVTTVRILTN

PDTPEKRHIEFRFQGDTTLRPGDHVNVLPVNPPSTVLRVLAQFNLAPDYSITINSFNTLGLPQATPVSASELFSAYVELS

QPATRN (0)

NLRILAATAQSDEDKQELIHLQ

DSYDSLVRDKRVSVLDLLEQFPSVSLPIAAFISMLPALRLRTYSLSLAPSFKPSHGSLTFSVVNEPARNGNRRY

LGVGSNYLASLTPGSILYLSPRPAKEAFHLPVDQSRIPIIMICAGSGLAPFLSFIQDRMIWQQQDKPLARALLFFGCGGR

FLDDLYHEELSEFEAAGVVDVRRAYSKVLDYDMARGCKYVQDRLVAEANAIRHLWAQDATIYVCGSADMAKGVEGVLEKL

LGMLPRERYVTEIYQMQTRDNVSEWLI*

 

>CYP527D2 Aspergillus niger

e_gw1.21.29.1|Aspni1

59% to CYP527D1

MDFYKFATFIVCFFIGWYALTSVLAWYRLRKFPTPSWLAHFSYLWLGRLTYSGKQYWVHRELHRKYGPLVRIGPNEIMTD

DPDIIRSMSSTRSTFTRGEWYIAGRFNPHYDILFTVLGNDAHKKARSRVFEGYSGRETGIAVEHGMDRQVTRLIDLIRQK

YAVPGQDAPLLNIVDISSYFTMDVITELAFGQEFGYLQAEEDRYGFFHEVHSLWPQMSTVADVPWIRRIVFSKPFLKLLG

PRTTDSHGFGALMRVAHEHVQQKFSTLDNSKGDMMESFIRHGLTQEECEAEGLFTIIAGTESTAGTIRSILIHILSSPVV

YSKLKNEIHDAVQKGPISSPISNKEVRDLPYLQAVIQESIRMRPPLLGLFPKVVPAGGVEYHGQFIPGGTHICMNTSSLL

HSKSLFGNDPSVFRPERFMEASEDTCSERRKNLELAFGHGQNQCLGKTIAIMELSKVTFEMFRNFDFQTVSPWRVNHQVQ

SYGVFLESNMKFRVSQSE

 

>CYP532J2 Aspergillus niger

e_gw1.2.1446.1|Aspni1

63% to CYP532J1

MALLTTTLTYLSQHIPSILFTILIIHLARNYFKPGLSRIPGPFFAKITNLWRFVDVARGRAEVTHYQLHQKHGEYVRLGP

NVVSVWNVEALKVIYGIKRGYKKTAFYRVQQQLVKGKPTRTLFTTLDEDLHAKIKRPVSAAYSMSTVTEFEPFVDSTTQT

LFARLDELSEKGCVFDISTWLQYYAFDVIGEMTFSKQLGFLREGRDVEGIMESLEKMFDYAGKIGQMPWLDYVLIKNPLR

QLIRGGSTGAVARFARDRLHERLSQGGSKRDDIHERQKDFLTRFLEAKSIHPDVVDDAQVFSYTTSNVNAGSDTTAISLR

AILYYTLKNPRVFSKLQDELNGALQTGKVTIPVSWKQSQELPYLDAVIKEALRLHPAVGLLLERVVPAEGLQLPNGPFLP

AGTVVGVNPWIIHRHAIFGKEIDRFVPERWLRGNDESEAEFKMRRQNMLGATLTFGAGPRTCIGKNISLLEIYKLIPSLL

LAYKIELSEPEAEWEVVNAWFVRQ

 

>CYP537B3 Aspergillus niger

e_gw1.14.367.1|Aspni1

71% to CYP537B1

MLGLWCAAILILVFLYQRLSSPISKLPGPWYTKLTSLVIKYHEFSASRRVFIHQLHKRYGTIVRIAPNEVSFASLDAIRE

IYASGGSGYDKTEFYDLFRQ

TMFSTLDKQT (0)

HSERKRQLADRYAMSNILREHHISAIRHSAKAFVSKCAAVAKSVDVYVYL

HCYALDCVTHFMFSPSGLNSLTDDNDFELMEELTYHNSLQKNLLPYYLPRLAPYFPSWLLPRRAPKANMYVHRVTAETNP

DEHSLLARLLRKDASLSKSEAAAECKDHMAAGIDTTGDGLCFLMWELSQPHNFPFQDRLYEELRSAPEDTPIDRLPYLDS

VIKEALRCAPPIPMSFPRYVPRGGRTIDGVFIPEGNIVSCQPYTVHRLDTKVFPEPDMFNPDRWTKDEGFNERNRLFFAF

STGGRGCTGRNLATVEMKILLQEVYSRFRTTVAPDMTSSMEIDDQIIASRPKGQKCRLIFTPREI*

 

>CYP539D3 Aspergillus niger

e_gw1.4.261.1|Aspni1

67% to CYP539D1

MLEYLVGQMSPMKASACLVGIFLIACLVRKFQVSLEVSRLGLRAPRIRFRLPYALDNVYGYVMANSRGEDLTHWQNLMET

AHGASAIDHVQTAELDFGISNRAIVTKDPENIRALLTGQFADYGKGEPFHHDWKEFLGDSIFVTDGELWSRSRQLIRPMF

TRDRIVDTEIFEHHVQHLIPLLAGTKSNKVVDVTPLFLRYTLDAATAYLFGDGTNSLQNPATSFAEAFSYVQHRQSEIFC

YGYTSTNNRSISPFNPILSRTKFRQELKKMNDFMAPFIQRALSLSPEELDTSLSKQETFIHALARFTRDPKVIRDQLTAI

LLAGRDTTATTLAFCFFELARNPSVVAVLRSEIASRLGLGPSGRKPTYTDLKEMKYLTAVLNETNRLYPVVPFNVRYALK

DTTLPRGGGADGNGPVGIRANTRMIYSTMMMQRDPAHYPPPGSKNYFDPGKWVPERWTGDWVPKPWHFIPFNGGPRICLG

QQFAMIEMGYTVVRILQVYESLRAMPPAGKDKVEDPMLRFKITLNPGSELNCVFE*

 

>CYP540A4 Aspergillus niger

fgenesh1_pg.C_scaffold_1000410|Aspni1

85% to CYP540A3

MQCHFYLIGEAVATAQCLEVDTLWKFEDLQRAVGGVFHVVQPTGISFHASSNDTLKTVSEVLAAATSTSPVGLRIDGNAV

QAPQGPPGLPLVGSFYEIYPDHLGNHYRLFRKYGPVIKTTN MGKTIYLTDDPQVAAACFAESAYMTKKINSDHPLWGVKD

NTAIFIGDTETENWRLAHKFLPPAMGPKAVRHYTGLMQECARKSLPVFDELDVRDESWNVYQYMVKLASQTIGRFSLGKD

FGHFDAVDSPLHPIVTNIASLLSLNKKITARGEWYRHMPFGDPARLRHVQHTIYSLLQEQVDTVTAESCSTDAPMADAAL

SATCVVDYLLHAVDETGAHFPPSLILANMLIVTGAGFTTTSALMSWLIYCLVTYEGTQDRLYAELVEYGIVGPTGERNET

AWTPDLAHSLPYMDRFVKETQRLHNASFQPGRTTKTDVILPGGYLLPPNSVIVPALYAIHTNPKVWRDPFRFDPDRWDTD

EVKSRHRCAYVPFATGPRGCIGFNFALLEVKVLLGELVSRYEFVRDGQEAIDYDPEFQLIRPLNFYVRAKRRA*

 

>CYP540B12 Aspergillus niger

fgenesh1_pg.C_scaffold_3000327|Aspni1

76% to CYP540B7

MPSQTFYLLGESPSSAKEIQIDPSATIDDLKHLIAAHFAIVEPSGIGFQGYDAALSELSEVLAAPGPLPLTIDGHAVREP

PCPRELPFVGTFFEVYPDHLGNHQRLFERYGPIVKTNNLGRVTYQTNDPKIAAIAFAESDFFTKKINEAHPLAGLKTPSA

GIFLGDTDTEEWRVAHKFLPPALGPKAVRHYAPTMQKTVEDSFKVFDALDEQGEAWNVYQYMLKLGSQAVGKLVLGLDFK

HFEAPDAPVHEMVHNIAEMLSLNKKVTSMGNWYAGLPFGDPKRLRSLRTSIENMVAESMEAASRGGHEDLPLQDAALKAD

NMVDYAIRATDNKGQKLPQSSLTWALVVATGAGFTTTSSLLSWLIYGLCVYPGMQERLLQELVDHGFDENTEITADFTDK

LEFLDKYIKETQRRHNPSFQPGRTAKVDLVLPGGYKLPKESVIVPALHHIHNHPDLWDNPARFNPDRWDTEEVKSRHKAA

YIPFAMGPRMCIGFNFALQEVKVFLPKLVYRYKFSMEDNGPIEYDPMFQLIRPNNLYVRAERRVRWPPKSRATAA*

 

>CYP540B13 Aspergillus niger

fgenesh1_pm.C_scaffold_1000635|Aspni1

81% to CYP540B11

MSAKLFHLLGEPVANAREIEVDSSLDYDGLRNLIAAHFAIVDPNGIGFQSEDAVFTSVAEIIASETPISIAIDGKPVREV

PGPKGLPIIGNFFEIYPDHLGNHQRLFEQYGPLFMTTNYGRTVYHTNDPELSAIVFSESDFFTKKINESHPLHAIKNKEA

GVFLGDTDTPEWRTAHKFLPPAFGPKAVRHYAPVMQQTVEDAFKVFDAFDEQGEAWNVYQYMLKLGSQAVGKLVLGIDFQ

HFANMNAPPHELILLIAESLELNKKITARGDWYAKLPFGDPKRLQQIRGRVWNIVDESIQNASRGGVEDLPLQDAALKAH

NMIDYAIRATDNKGEKLPKTSLIQALVVATGAGFTTTSSLLSWLIYSLVNYPGVQDRLLQELVDNGIDADTQITADLTDR

LTFMDKFIKETQRRHNPSYQPARTAKVDMILPGGYKLPEDSVVIGALHHLHNNPEVWDNPTRFNPDRWDTEEVKNRHKSS

YIPFAAGPRMCIGFNFALQEVKVFLPKLVYRYRFTKETDGPIEYDPMFQLIRPNNLYVRAERRVKWPPKTESPLPTASL*

 

>CYP541B7 Aspergillus niger

estExt_GeneWisePlus.C_21802|Aspni1

67% to CYP541B3v1

MPSPIPKPPGVFLLGNVKDVDAANPWNSFNKLAAKYRPICKVTILGVDIVLITGAALLEEICDETRFQKCVAGPIIEIRE

AVHSSLFTAKINDKEMSQWGVAHRIMAPLLTPGAVDQVFADMREVSTDLIKKWTAGPRQRINVTNDLDRLNHAANMLCFF

DQRLHCLEGPEPSLIKAMENATTEAVRRSSRLKLVNWLFYQRKFNAYNKTLRDYSASCMDYRRAHPSAKKDMLYALMEGK

DPETGEGLNDEQIVDEIINVFIGSATAPNLVAFGLYYLMKNPHVIKRAREEIDAVVGGPGAKIEHEHLSRLPYCLAIAQE

TMRLAAPAPGFNREAIPNQEGPVLLAGGEYEVPRKQALIAVLYGVNRDPAVFEDPDAFKPERMMGEAYERLPSAVKKGFG

TGKRVCIGKKYAWEWSYFTLVSILKDVEFELADKDYVTDGAGNNYNGAFTVKPLDFSAITGPRPRAG*

 

>CYP547C4 Aspergillus niger

fgenesh1_pm.C_scaffold_14000128|Aspni1

75% to CYP547C3

MDSLVLLGASLVEGYLLQHSLLPDWAFRSVTLLALAGNLILRLVWGVVIYPYWVTPLRHLPTLPGNLNHARVLSDDPRGR

LPLRWMKTIPNNGLIHFRDIFNRSFLLATNHQALLDIMSTNTYDFEKPWRTREFLARIIGFGLILSEGSAHKKQRRALTP

SFNVRHIRALYGLMWEKTGLLMDELQKEMDANEGCVEMSVWASRLTLDIIGPAAMGRDFRSLHNPENKVADSFLAILEPT

REKIAFLAVNVLLPQWFARKLPWRLNKVIDTETGYLRDLCKDIVAEKRAAILETKATAAELEADILGTMMLGGDFSDDEL

VDQMLTFLAAGHETTASAFTWACYLLTLHPTYQPLLRDEIRSRIPTASSPITHADLESLPLLNGIVQEVLRLYPTVPLTL

RESIRDTTVANTAIPKGTRLLLCPYAINRSPEFWGEDADMFRPERWVDTDKEGNQIVNGHGGAGTNYAQITFLHGQRACI

GKDFAKAELRCALAGVLGRYEVEMKDPTQVIHIAGAVTTKPVEGMHLRMRRVEGW*

 

>CYP548C2 Aspergillus niger

gw1.16.377.1|Aspni1

54% to CYP548C1

AM270216.1

MIDSQVLLTFALKGLLLGLIVLSCTVAG

LCIYRLFFHPLAKYPGPWLAKTTKLYAGYHAWRGDLHLDMWRCHEKYGDFVRYGPNSLLVNTADGLHDIYSHGKNFKKAQ

RYAAMVHRAPNTLTVIDKKKHGKKRRVISQGFSDSALKNHEVVILEQIQHLCTQLKAGEGGKPVPADTWSTPKNMGRMTD

YLAFDVMSNIIFDCPWSTLRFPTFRFVPEVIERSNVRVGTLAQSPELSIFRLDKYLFPEAIKARDMFIGFVDVMLTQGIE

AASKTGKGVFALLAKAKDPETGLPLRNRELGGESATLIVAGTDTSSTAMAACFFYLSHNRAAYERAVNEVRSVFSSPEEI

RMGQQMSQCVFLRACIDESMRMSPSAAGSLWREAEEAGATVDGQYIPPGVDVGTCIYSIHHNPAYYPEPFCFQPERWIAD

ECRSVQGDVGRARSAFNPFSIGPRSCIGKSLAYVELHLVLARVLWEFDIRLPEGDLGKTGEGKVGAEYGRHRLDEYQLYD

HLTAAKVGPYLEFCPRK*

 

>CYP548D8 Aspergillus niger

fgenesh1_pg.C_scaffold_9000084|Aspni1

82% to CYP548D2

name typo: was labeled CYP584D3

MLAQIGWQALSVTRLGWGLLALLVGL (0)

NQSLIYATYNRFFHPL

RRIPGPLLASITPWVQLYHGLQGDRHLWLCALHEQYGSHVRVAPNFVSVNTAQGLHDIYG

HGKRLKKADFYNAFPAIKGVYNTHNVIDKVMHGRKRRVLSQAFSDHALKSMEDVMLLHVR

QLCAGLARAQQTGVVQDMGRWFSYLTYDVMGELCFGKSFDMLIESSRRRLIELVDRAANRHYV (0)

CGLWMPLDRWHLDQIFIHRLTNDRWNFIMNSRVEATKRAQE

RTKAGHDAKRDFFYYLLNARDPETGQGLTTPELWGEANVLMIAGSDTTSTTLAATIFYLV

RNPQAMAQLQKEVRENFTSVEEIVTGSKLNELVYLKACLDEALRLAPAVPGAPPREVMEG

GAVVDGVFLPGGTDCGTPTYSIHRQAAYYRQPGAYLPERWIEGAICQTGMEAWQTTREDV

EMARRAFCPFSIGPRGCIGKSMALMEMRLTIARLMFLFDMQLADRRGEDEEGHLALVDHF

TSAKEGPDVIVRARAV

 

>CYP548H2 Aspergillus niger

gw1.11.642.1|Aspni1

56% to CYP548H1

VYAIYHLFFHPLAHFPGPFWAKFTCLYSGYHAWKGDLHIDMQRCHEKYGDFVRYAPNQLLINTSIGLHDIYGFGRNTQKS

KLYSAMVHRAPNTLTLIDKKAHGRKRRIISQGLSDAALRRYQPAILKHINELCGALVGSKPSEWSVPRNVAHYFNFLTFD

IMSDVLFGEHYNMVTSEEHRYVVKAIEDSNVRTSVLAQAPLLAFRRWDRKIFAESILARNKFIQFVNTLLQRRFKAAKSA

RQDVFTFLLDAKDPETQQSLSLAEIGAETTTLVVAGSDTSSTAFSSCLFYLSHNKDWYNRVATEVRNTFSSPDEITLGPR

LSSCIYLRACIDESLRMSPPAGSALWREVGPGGATFDGHFIPAGCDVGTGIYAIHHNENYYPEAFNFRPERWILAGAEGD

TEAVGMADRDSLAKAQGAFNPFSIGPRGCIGKGLALAELTLGIATMLWRYDFALGEGKGMALGAGRKGLGPGRERENEYQ

LYDHITASKEGPMVCFRER

 

>CYP548L1 Aspergillus niger

gw1.12.692.1|Aspni1

51% to CYP548K1

VIYLLFLHPLAKFPGPIFASLTHGYGAYHSWKGDAHLDMWRLHEKHGDFVRYMPNSVFIRNADALHAIYSTKAYASVVKS

PHYEVLQAGSVGSTFSLRGGHEHLRRRRIVSTALSEKAQRGMDPRIAVHVRKFCEAVLPARQGELGEPMNMAEWCGYLTF

DLMSDLVFSASYNLLGREKFRYMPEVIDKSNVRMSVLAYMPILAAWRAVDGIFFRDALIARNRFLRFVVRAVRERANRAL

GKWAPDALDPCKPRDDIYSALATAKDPDTGEGFKPSEMVSESTTLVVAGSDTTSTAIAATLFYLADNRFAYEKAAQEVRT

VFAGKSLGSEEALSGPELSQCTYLRACIDEALRMSPPNGAALTREVLPGGLTVGDIHIPGGVTVAVPLYAIHHDERYYVD

PFTYRPERWLEDDGTGSIKRARLVFNPFSLGMRGCLGRSLAYHELMTTVATVLYLSDFEFAEGPMSKVGRGVPGAVYGRH

RENEYQLREHITGQKDGPWLRFSRRE

 

>CYP548M1 Aspergillus niger

e_gw1.8.742.1|Aspni1

67% to fgenesh1_pg.C_scaffold_4000313, 42% to CYP548A2

MDLLGCVVIAVAGYIIYQVWFHPLSSYPGPFVAKLTNLYSVVHAIRGDRHEDLYHLHQRYGPVVRVGPRRVSILDAKALE

PIYGFHANVQKAKSYNIFYGVSIFNAIDRTVHARKRRVMSHAFSSQALRGMEPHILSAIRDWCAALGDQHPDKQVLSACS

RPGSWSRPKNMVHWSACVVFDALGEICFGKTFNTSFSDANHFFFPLMALNLRIMNICGQMPILCSLGLERYLRRGTVANR

QRQIDFSRQQLQTRLAAESTQRRDIIFYLQQARDPKTNEGYSEAELMSEVMTLLGAGNDTTNTTLTAIFYYLAHNPAILA

RLSAEIRAVFPTLEAIVAGPDLSQMAYLHACIDETMRVCPPVPTDLPREVLPGGLRVGEWYFPAGTVVAVPTYALHHSED

HFYRAFVYDPSRWLLCGSKGTEQGEGVSAEVLSRQRQAFAPFSMGPRACIGRNVAILELELTISRALWLYDIRLAPGTEQ

LGVGYQGEYKIKDHFAVGKEGPVLQFRMRQK*

 

>CYP548M2 Aspergillus niger

fgenesh1_pg.C_scaffold_4000313|Aspni1

67% to CYP548M1, 44% to CYP548A1

MLDNFIQLVLGTISLGKLLFAILSAAGLSYVVYQVQFHPLAAYPGPFLAKLTNLYSVVHAMRGDRHEDLYKLHQRHGRIV

RIGPNRVTILDARALEPIYGHQANVQKSQWYHNFYSVSIFNAIDRNVHARKRRVMSQAFSDHALRGMEPHILSAIRDWCL

ALGDEHSNQSQGKQSQASSSSSSSSGGGWSRPKDMVHWSACLIFDALGEICFGKTFNTTRSDENTFFFRLMAVNVRILNI

CGQMPLLRRIGFDQYLRMGTAGDRERQIAFSRQQLSTRLAANPTERRDIIYYLQQARDPETGEGYSTQELISESTLLLGA

GAETANTALASTWFFLAHHPAIRQRLTNLIRAHFASLESIVSGPALSSGKMGYLRACIEESMRLCPPVPMDLPREVLPGG

LQVLEWEFPAGTIVGVPTYSLHHSPEHFDRPYEYDPNRWMLRGTEAADEGVGVSPEVMARQRAAFVPFSLGPRACIGRNV

AMLELEVSVARVLWLYDLRLAPGMEHLGVGREGEYKMKDNFIVGKEGPILEFRKRA*

 

>CYP573A7 Aspergillus niger

fgenesh1_pg.C_scaffold_11000284|Aspni1

77% to CYP573A3

MSVGEDLLSKVTVTNVILGVVVYVVLQFVRQIVYYHFFHPLSKFPGPFWGGVTRLWIAWHNLRETELQTVYDLTKKYGPV

VRITPTLLLVSDPKKLPDIYHRNADKTGHYITGSFGETESLFNMRSHKTHAAFRKHIAGPYSFSSVKRMEPLLDAHIEHW

LQKIDERFASTGAGFDFSWWAVYMAYDIISEVGFGAPFGFVEQGQDVGGLVQGFHDGLPAFGLLARLHPFTSWMKTTFMK

KYLVATPQDDSGIGVLMRFRDRLIDQRLRDLEEKKDIGRIDLLQTFLEARTEEGKPLDMDYIRAEVLLVLLAGADTTGTV

FQALVHNLMTHTEVYERMMAEIDDAARKGLISPMAQYQEIVEHLPYYAACVRETLRMNPAAPNIFPRYVSEPGIDLYGQF

APAGTEISSNPWIVQRDEGVFGADANVFNPERWLDPERAKVMNKYMFTFGYGTRVCLGKDIAMMELFKGPLQLFRKFKLH

SIAGKPSAHFVIKGGVGFWRDMWVTVDKRGAVKAT*

 

>CYP576A4 Aspergillus niger

e_gw1.20.142.1|Aspni1

68% to CYP576A3

METISERLPVYFHWAPLFILALLFFNYIIGVTKAIKSPLSRIPGPWYAPLTTLHLNYAFAKGTIWKAVERSHAKYGPIFR

LGPRQVWISDKEAIKAILMTVDLPKVTMYAEISRDRSSPGLFGEIRPDPHKRLKKFLSPAFTIAYVDGLEFLFSECVGDL

INRYVDLLSSPTSRGQKELVVTDLMQDLHSLALDIMGECSFGNGFGQTNKNKKLELELDEGIWRSIPTAIFKGMTRRYQF

VYIKRLLRRLGLNIEFDWPREMIAAISAVAGHRKAKPKSVRPDLLQHLLENGERPDSGVKMGTREVVDQMAEILLAGSET

TSGTIACFFLEILRNPEIKEKLLKSLPVLRPSDPIISSKTVRTSPEYEYLEACIKEVLRLHPIASEMGRRTGNTPVKLMG

YYLPAHTIVSASYRQLHRDPKYWVDPLRFWPERWLDPRPSDVPAPDMHAYYPFSAGKHSCIGKNFAMAEIRMLTANILSR

FDLDEVPGQNIDYRQYITMQFEHGSWKAFLTPRYEQSTPVS

 

>CYP578B5 Aspergillus niger

e_gw1.3.1489.1|Aspni1

56% to CYP578B3

MLSILLLAILPIIYLIHKYFTDPLSRIPPAHPLSPYTTKWITHHRDRTTEVKAIYTAHRARGPIIRLSPTELNVNSLEGL

RAIYTQGAFEKHAFYADTFMNFHTPNMVGMLENKPHGEQKRLLSGVYAKSYLLRSSDVKVLGREMVVGRLGEFLRGVVAK

GAVINVLPVFQAVGMDFTSGFVFGMQNGTRFLEDLTSWGVWLGQYEAFKSMSREERFMGFVERWCLGLCEGVGLSKQSGG

PVTQAVVYDRLREGLEEKKKVSGEDVDVNLAVASEVLDHLVAGHETTGITITYIMWELSKRPELQTRLRKELASLPGSLR

YTEGMEKGLPSLADIDALPFLDAIVRETLRLHAPAPAPLPRVTPPEGTWIHGYYIPGGVQVSSSAYSLHRIEEVFPSPEE

WIPWRWMDVKDDKIHDMRRLFYPFGTGGRMCLGSNFALLEIKLVIAMVYANFAPEVVDDEGIGQHLEFIALPKGRKLMVR

FVPV

 

>CYP578C6 Aspergillus niger

e_gw1.1.562.1|Aspni1

75% to CYP578C5

MTPTVSACEDYTDSSTLHHGRTVSMFTMTNNKAHSTRKRMLSNIYSKSFLQSSPHIHLISETILLDRLLPIIQDAASSGS

PIEMHDLDQGITMDFVSAYLYGLANGTNFLQDEAFRCKILRLYQSRKPFEFYHQEVPNLVSWTKRLGLRLIPKWCDEANE

VLDAWGLSFCDKADECLSSTQLNTEPMVYKQLKQSISKQLPPKEAASYNKLIEQQRLDIACELYDHLTAGHETSAVALTY

LFWELSKHPDLQSALREELHTLEPKILYPRPSSSRDLPTPKSIDSLPLLDAIVTETLRLHAPIPGIQPRVTPSPGCTLVG

YSDIPGNTRVSAQAYSLHRNPEVFPEPETWQPKRWLKDCNPSEVLEERRRWFWAFGSGGRMCVGSNLALQEMKLVVAAIY

TNYMTAIIDDEDIEAIDAYTVKPRGEKLVLKFESVA*

 

>CYP578F1 Aspergillus niger

e_gw1.1.426.1|Aspni1

46% to CYP578C4

MEASILPSVPACAGVALVAFFLYHFIIYPSFLSPLAKIPNAHPLAPYTSLWILWARYRIRENNTVLRAHQQHGEVVRLAP

NEVSINCVNDGIKTVYGKGFEKPPFYSVFVNYGALNMFSSLHSPEHAMRKKRISNIYSKSFLQSSPDAAAIIQEVVQRRL

LSQFASHAKSKQPLDIYPIYKATAMDLTTSYFFGLSAGTQFLIDPTAAARWQELYLDDQHPARHLAHDQIAAWCLNMSDG

AEKMLAKKAGGSSLPPGHLPVVYERLRQSTEKEGMSPQQLQVTSELLDQLIANNGTVATTLLYVTWQLSQNSAALARLQE

ELRSKLGPEAFAWSASKEEDTLPKAKDVDELPYLNAIIMETLRLHAPVAGSQPRITPENNKTTLGQYENIPGGVRVSAAA

WSLHRNPAVFPRPDEWHPERWLSENLEGADKKERWFWAFSSGSRMCIGSNLALYLLKYVVAAIYANFRTHIVNDEGIEQE

DGFISGPKGNQLTVRFESITVD*

 

>CYP584E6 Aspergillus niger

fgenesh1_pm.C_scaffold_19000013|Aspni1

67% to CYP584E2

MIALGAALCFFYVIKILRRKWIQSQIIRDTHCEPAALGSKDRLFGIDVLLQNFQAAKNHRLLELIQRRFQQYGNTFRVKR

FATPFIITCEPANLKAVLSVKFKDYGLGSRIETFGPLLGHGIFTSDGEHWAQSRAMVRPNFVKDQIADLEKLEELMLGLL

ELIPTDGSTVDLQDLFFCYTLDSATEFLFGHSVQSLNQLRSGVVSGENSFASAFNYAQHAIARNTRLGFLRRFVRDHKAM

RSNRICHNLVEQFIDKALKYREDYTKKTSGDEERRSRYLFLQGLAEHTGDRDRIRDELMNVLLAGRDTTASLLSNLFFML

ARKPNIWKKLREEVATLNGCAPTYQQLRNLTCLKHCLNESLRFHPVVPVNSRKALSNTVLPVGGGPGGKSPVFVPKGTIV

FYSVWAMHRRQDLYGPDANEFRPERWADLRPGWEYLPFNGGPRICIGQQYALTEAGYVTVRLAQQFSTLESRDSGPWEEA

LTLTLCSRNGTKVCLRN*

 

>CYP584E7 Aspergillus niger

estExt_fgenesh1_pm.C_10613|Aspni1

67% to CYP584E2

MAFDKVDHPVITIATVILVLWCTTTYLQRKWTHRRIIKANNCQPPPSYPQKDPIFGLDILFEQIKYSKKHKILERAIERF

KLYGNTFRQRRFTPFIITCEPENIKTVLSLRFKDYGLAGRIDAMGPLLGHGIFTTDGEHWAQSRAMVRPNFAKEQVAHLD

IFEELVNELISLIPTDGRTVDLQELFFELTIDSATEFLFGHSVHSLRKRRVGALDSTEQDFASAFNYAQKAIVADLRLGR

LKYLRRDRKVGECIRICHELVEQFVDSAMRVREQSSEQKAPPVGDSHDAKEKHKYLFLHGLAQQTGDRRRIRDELINILL

AGRDTTASLLSNLFFMLAKNPRIWNKLREEIAFLEGRAPSYEQLRNLTYVKYCLNESLRLHPVVPANLRFANTDTVLPRG

GGPDGKSPVFVPKGCTVAYNVYALHRREEIFGPDANEFRPERWAEIRPGWEYLPFNGGPRICVGQQYALTEAGYVTVRLA

QKFSVLESKDTGQWVEGYALTLCSRNGTKVALS*

 

>CYP584E8 Aspergillus niger

estExt_fgenesh1_pm.C_40266|Aspni1

76% to CYP584E5

MEFHPKLIILLLTALVIAGESFRRYLKRRQFARRHGCEPVARSFSKDPFLGLDTILGTMRTRREHRILERSCRLFRTLGN

TFTVKELGRSAILTIEPENIKTVLSLNFNDYSLKHRYEAMKPLLGEGIFNTDGHHWATSRALIRPSFAREQVTDLRLLEE

LIQDLFALLPRDGSTVDLQELFFRYTIDSATEFLFGQSVGALKESHSEVGFAEAFHYAQMAIPMRGMLGPLGVFFRDRKA

EECNRICRDFVQRFVDEALYAAATRKEDEATETKRKYIFSHELASRTSDKQRILDELMNVLLAGRDTTACLLGNMFFVLA

KNPAIWARLRAEVESLQSRPPTYEELRGLKYVQCCVNESLRLHPVVPRNEREAAKDTILPVGGGKDGLSPVFVPKGAVVG

YNVYAMHRRPDIYGPDAEVFRPERWEDGKLQPRWGYLPFNGGPRICIGQRYALTEVSYVLVRMVQEFRSLESRDPGPWVE

GLALTLCSRNGAKVGLIPSHTN*

 

>CYP584H1 Aspergillus niger

e_gw1.19.73.1|Aspni1

44% to CYP584E2

MALHGLHALAVIALLWPLLLQAIYRAFRASSCQRFRLLHGCQSAPKGGRRSLPFGIDNLAVLWRATRENRVLETVESDFR

SSGHTTMVQRHLNRRMVITCEPENIRTILSLKSEDYSVESRNQAFGPLVNTGILISDGVTWAHSRGILRRNFTRSHLANF

EPLEQTLQDLISLLPRDGVTVDLQPLFLRYTLDIASGLHLGQSLHSLRQKAASNGKPTRIDEFKEAMGHAAKDVARRHHL

GVLRYFFIDLRARKSYRTYQAFVDQLVEEALRDSKKSSLASESSCASSGPYVALHEWLEQTTDRRRLRDEVILMLLTSGD

TTASLLGNLFSMLARHPTVWQKLRAEISSTLQGRRPTYEELPRLQYLRYCINETLRLIPSIPLVDRVARRDTVLPVGGGP

DGKSPLMVPQGSQMVCCMYSLHRRVNHFGSDAEEFRPDRWATRQPGDEFMPFSTGPRACPGRQFALTVTEYVTVRLVQLF

PRLEGRDAQPWQGDLSAMLLPKNGVKVALWS

 

>CYP586C3 Aspergillus niger

e_gw1.3.1357.1|Aspni1

63% to CYP586C2

MFAQTILLILLPLVVSYFITRIRYSRFKKYADWPQLPTSLVWGHMKALHEFIVRGEEKRHIDIVFGEIQEHLGNPPLMFF

DLRPVQFRLCVVGSHEIAEQVSRSTKSFPYSMQKSPTMGALEPLLGPYSIITQEGEHWKGLRKRFNPGFAPQHLITLLPC

ILDKAIQFTDILDAYARSGEELSLDERCVSLTFDIIGAVTMDKDFHAQLDRSKQDELVRLYRELTTSYRSGSGIQWGWLD

VRVLWRRRVLTRRIDHLISEHIKTKFDELKSKSTEKRSRSVLSLSLQDIDQLNTRVIQETCHQLKSFLFAGHDTTSIVLQ

WSFYVLSRTPRVLDKLRRELDDLFGPDPSPAAVQEKLLAPGGDDLLKRMSYTSAVIKEILRLYPPSGSARYMPPGTGFTV

QLPDGKTLCLDGVVVYNNSTLVHRDEKVYGPTKDEFIPERWLGDADTGLGLSTDNVEDKGNGPVATACIPASAWRPFERG

PRNCIGQELANLEARVILACTVRRFDFEKVGVGAIARDATGAPILDAKGQYEVESELFNTMQVTAKPIDGTVVKVHLAER

AS*

 

>CYP586D1 Aspergillus niger

estExt_Genewise1.C_70085|Aspni1

44% to 586B1

MLLLLLLTTIFLTSVWICRWIWYERFIKFAQFPQLPPSLLWGHLRIYHEVMQSGSLDRDHDHIFSQIHESLGRPPIVLFD

YRPICRPVLVIANHEVGEQISRSSKQFRSSVPKLGLSFLEPVIGHTSILSAEGEKWKALRKTFNPWFSLQHLMSLMPSIL

GKIEIFVTQLDALSVSGDEVSLVTLTTNLMYDIIGNAIFDIDMDAQHLEPGHQGELVRAFNDLINAYWDDKIHLPWFFTP

VNALKRRRLGNRVHRIMKSIVRRKHEEHLWRQQQQRRTNGYEKRPQPQLPPSITLLSLQETTHTGGILTPELLDQTCDQL

RTFLLGGHDSPSATLAWAFYELSRTPRAQAAVHAELDGLFGPGRDAAAVRTALASPTEGPDLLRRMVYVEAVLKETLRLH

PPASTARYSPKGSGFVVRLPTTGEELCLDDLILYNCSAIMHHDRGVFGSTANQFMPERWLMAEDEKNTNQRTIPPSAWRP

YERGPRACIGQEFARITMRVVLAVVARQYEFIKVGIGALARDASTGLPILRPDGRYEVDSQVYTTRQITARPVDGLKVKVK

 

>CYP613C3 Aspergillus niger

fgenesh1_pg.C_scaffold_11000488|Aspni1

53% to CYP613C1

MDTTILLAGQAVLIVVILVAVKFRTPITNRINRLISAILRWPDGQGDGAKFLQGQSNSERWERQFGAIYRLWSGMNPEVV

LTRPEHIQAVFKDSHTHLKAKNNNSGYLLGELLGQCVGLVSQDQWQRVRAIMEKPFHRNASTTYLPLVKRRTEQFFQELW

DTRDLSRGLLDPADDLKLLPFLVVAEVVYGRLAPDVEAELRRLAPQRENLMKHVIKGGLTRFAWSRFLPTQANRELAAFQ

QRWLAFNELAHRRAVEQKLNAPIIDFFAARDAGQISTQELLHTLDEMLYANLDVTIGGVSWNVVFLAAYRDIAKRLREEV

EQQRAISVDGEVDAYLLDNSTLLAACVEESARLRPLAAFSVPQAIPTARTVGGYHFPAGTNFVVDSYALNIRNPYWGEER

HLYQPDRFLARSLTQARYHFWRFGFGPRQCMGKFVASVVIRAILVHLVEGYDLRMVKPEAMEEWGRNKEIWINHPDMKVR

S*

 

>CYP617D6 Aspergillus niger

e_gw1.4.269.1|Aspni1

61% to CYP617D2

MAGLPWNAIHVGIAVFTYFRSTFRNFLLLSAVTLVLRVFYRLALYPVYFTPLKHIPTPPGRAWFTGNNDSFILVNPYERM

RRWNQDIPNDGLIRFYLAGNLERMIATNPKVLSELLVQKVYDFEKPKIVRQSLGRITGEHGVLLVEGAEHKQQRKLLMPA

FSYRHIKNLYPVFWSKGIEMVKLIEADLQRRANPADNVIRVASWSSRATLDIIGLAGMNRDFDSLQNPTNQLAVAYHKLN

SVPPTPLEKGLFVIGLILNVPHLVHKLPFKRNRYIRESAAYIRNVAQEMIHDARQSIEGEKTHQTTDAVDILSVAIESGG

FTDEELIDQMMTFLAAGHETTSGALQWCVYALSQYPDIQTRLREEIRANLPPISVEAPEPISAATLDSLPYLHAVCQEVF

RFHPSVPNTVRIANRDTTLVGQKVPKGTVIQIVPALTNHDKSLWGPDADQFNPDRWLGPGKANTGGATSNYAFLTFIHGP

RSCIGQGFAKAELACLLAAFVGRFQFELEDPKKELILREAATVTPKDGVRVKVTPLEGW*

 

>CYP617E2 Aspergillus niger

estExt_GeneWisePlus.C_100429|Aspni1

80% to CYP617E1

MMITFLEFWLCTLCLTSGGVVHQVFTGGQHIALLFQVLGGHLVTLLGFALYWTVLYPRYFTPLSNIPTPSHRSIFTGNYP

VLFPDNAWVPLRRLAETTPNDGLLRIYSALSGEALLVTSPPAIRDMLTVNAFDFAHQDLVKIAIKRFTGSNLGFLSNDDF

KIHRKNMMPAFTVPHVRELTSIFWTKAKEMVHCMSTELRADPLAPINFREYVSRATLDNIGLAGMGHDFQTLKQPDNDLR

SHYRKLILDPTRVFSWVGLLSRYFDMRLLMRVPLKKLIEVSQSASYLRSVTKKVIRERSEKLFESDDGRTKDIITVALTS

GVFEERHLVDHVMTFLTAGHESTATAFEWTMYELGRRPEMQTRLRDELRESIGTNDLGATDFGSQVQALPYLNAFCSEVL

RCYPFSPIIVKVAQQDTTIMSHPIPKGTVVLYSAEVSNHDKKLWGPDADQFNPERWMGEGTAKSGGSSSNYAMLTFGAGP

RNCIGANFARATLECLVAAVVTTFEIELANPHTAGRLKFGQTKKSAEGVYGKLRFVQPVEA*

 

>CYP617F2 Aspergillus niger

e_gw1.1.329.1|Aspni1

54% to 617F1

MSGIVSGGATLLTAILSYDSPKISLGTIWFQIPLLLLLTWVTWRRLVWPNFFSPLRHLPSPHNRGWGMNQRLRVYTEPRG

MPQCDWVNSIPNNGLIRYRTLLNSDRLLVTSPEALAEVLTTKCYDFKKPKWLANELKKVLGVGLLLAEGDEHRAQRKILA

PAFSFRHIKNLYGVFWDKSCEVVTAMTDQLSCKEGPKTYGPRESSIVNTGVLDIAEWSHRATLDMIGIAGMGRDFGAVHN

PNADLVRAYALVFQPSKQDIMLAVLRLLLPNWMVDWLPLRRNEEIRCAVQRIRGECADLIRQKSKHQRKYHTSQHRDILD

VALSYGGFSDTLLIDQLMTFLAAGHETTATAITWAVYLLCVHPEVQTALRSEIREKLPSLEDSGSNLTSDNIDTMTYLNA

VCDEVLRYAAPVPLTFREAVIDTNILGQPVPKGTKIILVPRATNRDANLWGPDAQQFKPDRWLEGGIRSNYATLTFLHGP

RSCIGRSFAKAEFSILLAALVGRFEFQLEDDQLLDEKRMKVTRTVTARPANGLLVKVTSLAGW*

 

>CYP619D1 Aspergillus niger

gw1.16.300.1|Aspni1

50% to CYP619B2

GPPGAPLIGNILQLPKVRAHQKFTEWARTYGGLYSFRIGPATAAVVTDRALVKELFDKRSALYSSRPTSYVGQNIITRGD

HLLVMDYSDNWRLFRKAINQHFMASMCEKTHVRLLEAEHTQMMRDFLLHPEKHMLHTKRTTNSIIMSLLFGIRTPSWDTP

HMQELYEIMEIWSQIMETGATPPVDIFPWLHWVPQQWLGHWVDRSQTVARGMKRLYSSFHRRAIEARRKAESTSQSRART

FLDDVLDLQEKLGLTDNQVDFLGGVMMEGGSDTGSTMLLVMIQALALHPEIQQRARAELDAVCGEHRSPTWEDFPRLPYI

NMIVKETMRWRPVTPLAFPHALNKDDWVNGYFLPKGTTVFLNVWGLHHDENIFPNPDQFDPSRFEGRHKLAFDYAASPDY

MQRDHYIYGAGRRLCPGIHLSERSMFLGAAKLLWAFNFEPARDEDGNPIRIDTDPVTGYTEGFLVCPRPYQCNVTPRSPA

HAETILREFSRAESEVLSQYAMP

 

>CYP620G2P Aspergillus niger

gw1.10.879.1|Aspni1

60% to CYP620G1 partial C-term seq Pseudogene

IQAKAQEELDRVIGTNLPTTEDRTHVPYINAVIKEVLRWNPVTPLGVAHASTKEDVYEGYSIPKDATMVPTIWAFLHDPK

VYSDPMTFNPERFLTTESYQAERDPHNLAFGFGRRICPGRGFADSTIFLVRSLQAFRVAKIFEDGREIGPVVDYLPGVMG

HPKPFAISITPRSKEHESFIRSIEIEHPWERGNLVLV*

 

>CYP620H5 Aspergillus niger

e_gw1.10.144.1|Aspni1

59% to CYP620H4

MWTGAFIAITSVYIFFAVLTRKSKRPPLPPGPRRKPIVGNLWDLPDPSQQDWQHWLKHKDRYGPISSLSIMGQTIIVLND

ARLAVELLESRSSIHSSRPQQHFAEMAGWNNVLGAVKQSQRFRATRKNLHREIGSNVSVARFNEIQTAEVGRFLLRVLDA

PDKLMKHIRKEAGAIILKVGYGYTIEPHDQDPLVDLADKAMMDFSMAMLPATWAVDFFPPLKYLPSWFPGTEFMKIAQRY

RKNVTAFSDIPYAFVKEQMRTGRFVPSFLSNLLESSDLEPGSEEENTVKWSAGSLYAGGADTTVSSIASFFLAMALFPEV

QRKAQQELDTVIGTDRLPQYADREQLPYINALVKETFRWHPVVPMSLTHTSTADDVCEGYFIPKGSSVLANIWAFTHDPA

AYHDPMSFKPERFLGPKPERDPHFLVFGFGRRVCPGRTLADVNVYLTVAQALAVFEISKPVENGKVKDVQPEFLPGVISH

PAPFDVSIRPRSAKHLELLRSLEQKYPWEKSNAEDLK

 

>CYP620H6 Aspergillus niger

fgenesh1_pm.C_scaffold_4000144|Aspni1

60% to CYP620H1, 41% to CYP64A1

MLSIASLLVGLASIYVLYVFLGPKKTSAPLPPGPPPKPVIGNLNDLPPPGSKDWQHWLDHKEKYGPISSVTIFGQTLVVL

NDPDMALEMLEKRSAKHSSRPHLPIADLSGWDKTLGLLPYNNRFRAYRKATYRELGSANAVAKFDGIVDKEVTRFLLRVI

RSPNDLIDHLRKEAGAIILRIGYGYTIEPNARDPLVDLVDKAMDDFSQIVLPGAWLVNFVPFLKYLPTWLPGGKENQIAK

EYKERLTIMHDKTYDFVKNQMARGVHQPSYVSGLLEKDTVLPGSEEEIVVKYSAGALYGGGADTTVSALSCFFMAMALNP

SVQKKAKEEIDQVIGTSRLPDLSNQNDLPYINAVVQEVFRWHPVTPLSVSHASSEEDIFNGYLIPKGAIIVPNVWAFTHD

PTNYRNPETFNPDRFLGAAPEPDPRLYAFGFGRRICPGRLLAEKSIFLTVARALAVLDIRKKVRDGKEVPIRVEFSSGTI

SHPVPFEVDLKPRSKGHEKLVGAVEREFRGRRVMRRSWGSEDMDDWYIAR*

 

>CYP620H7 Aspergillus niger

e_gw1.1.1438.1|Aspni1

53% to CYP620H1

MSLLVRAITGLLGLLILKSFLTRKKFLAPLPPGPKPKPIIGNLLDLPSKGEADWLHWYKHKKIYGPISSVQVFGETLIIV

NDARIAVELMEKRSVIHSDRPSLTFIEMSGFKDIFSMRNNNDPRVRAERKLFYQQIGSNNSVARFNYIQEAEVGRFLVRV

RDNPEGLQDHIRKQAAAIILKLAYGYSVVPHGDDPLVDLIGRAMGNFGAALVPGVWLVDFVPFLRHIPTWFPGATFARVA

ETFRESARAWNCQPYEFVRYQMSQKKHAPSYISGLIEEKGVPEPGSFDEVVMKWSAAAMYGGGSDTATTISTMGGLFLAM

VLYPDVQRKAQEEIDRVVGTDRLPGFDDRDNLPYINAMVKESLRWHSVLPMGVAHCSSEDDMCEGYFIPKGSQILPNQWA

FTHDPDVYPDPMAFKPERFLATENHTPERDPHLLAFGFGRRICPGRTLADANIYLSIAQSLAVYRFTKAIKNGKEVDVEP

KFLTGAISHVAPFEVGIKPRSQQHEALLQALEAKFPWEKGHAEELSQVKF*

 

>CYP620H8 Aspergillus niger

e_gw1.6.1233.1|Aspni1

54% to CYP620H3

MSILTAVAFTCLILLPVYLLINHQIASLPLPPGPKGKPIIGNLSDLPPPDTPEWQHWLEHKKRYGPITSVTILNQPIIIL

HDAQIAIELLEKRSLKYSSRSQTVFVGEMIGWKDTLGMQPYNARFRAYRKAMHQVLGTKALVSKFNTLQELEARRLLRRM

LEDPGEWVQHLKTEAGAIILKIGYGYDINPHGRDKLVDLADDSMETFSAVMNQVWLVDLVPVLKYLPSWLPFSAQRKSQF

WRTQLLTTIETPYRMVREQMASGIAPPSYLSNLLQEEDTKEEKTLTAEEEFTAKWTAGSLYIAGADTTVSALRTFILSMA

LNPAIQEKAQAELDTVLGPHTLPKLSDRDKLPYVNAVVKESLRWYPVGPMGIPHLCVEEDVYDGYRIPKGAIVMGNIWAI

THDPNIYPHPEKFDPERFLGENPQPDPSGWVFGFGRRVCPGRVLADASVFVTVGMVLSAMRISLEKGDGEREEVRFTPGV

VSHPVLAGLKVEARSARHEGVIREVSI*

 

>CYP628D1 Aspergillus niger

gw1.4.1072.1|Aspni1

36% to CYP628B1, 38% to gw1.13.785.1s, 39% to CYP628C1

C-term is short

ILGITAHLTYFIHADLEKHVVFLVNCLIFWPSLGLIALFILGYRDISQWIGPAILSFHFSLLASIAIYRYFFHALDGFPG

PKLARITALWDFKNTVLNAKWYIKVKEMHGVYGDVVRIKPRELSINDPSAIKDIYGVGTTCVKGPFYDLHYPHRSLQMAR

DKAFHSKRRRLWDRGFTSKXALAGYEPYLLEHCKDIVRVIESRSSQAQEATALIDGFAWDSMGIFAFGKSFNMLHGEPPK

MLQMMRMMGRGASALLSSSWLVILMRGMVGVRRFTDRWLEWCAQCVEERSRVETNRRDLFSYLIEELSSEGDQSIGGVDG

DLVRDSELAITAGSDTAASTLNALFYLLARHPDKLRRLQEEIDTAVPADEELSHAALVKKPYLEGCINESLRLCPAVLSG

LQRETGPEGLRTAGVYIPPGMIVSVPTYTVQRDPRNFPRPNEFIPERWSTQPELVIHKEALNAFSSGTYSCAGKAFAMME

MRLLVSTIVRHFDIEFPPGE

 

>CYP630B14 Aspergillus niger

fgenesh1_pm.C_scaffold_20000049|Aspni1

77% to CYP630B11

MYIPIVILLLSLLTIYYFIIPIINYFRDPKGFQKYPNLTFWSGISDLPLVYFSHKGIRYKRLLEAHKTHPVVRIGPNYLS

YADPDAIKDIYGHGTTCTKDLFYSTLGGSHFHLADVVDKEEHARKRKVLSSAYALKNLETWEYKVADMTNRLIKAFDARC

TDPLPKGHRPLEKDLTIDYRMWTNLFTIAAIANIGLSEDIKFLDQGNDLITSESMDGMTKKVHFRDCLFATGSATATLVW

SYDWYKTLARASKILSPTYHRKWKLNKDWDGIVYNRATTRWKRYQNGEQLDDFFSALMADKSDVPHNLEWGEIVAEISIM

MNAGSDTTGISLSNVMLLLLNNPACLEKLQEEVDGVLDDDEIVAPYDKVKHLPYLRACLDESLRLYPPVSFALPRRTPPE

GTMILSDHIAGNTSVGMSAYVVHRNESIFPDPEAFRPERWLGEKGKELQPYFIPFSTGARGCIGRNISYLEQTILVASLV

HRFDFALPYPGWEPERHETTNLGSGPMPMKVWRREVAA*

 

>CYP630B15 Aspergillus niger

fgenesh1_pm.C_scaffold_9000258|Aspni1

88% to CYP630B12

MWSLFTIAPYAFFIGIVGISYFLVWPFVQYIRDPKGLRKYPNLTPISGMSAIPFMLMASRGFRSRELQELHQEKPVIRTG

PNTLSYGDVRAIKDIYGHNTKCIKDPSYVVTAGTHYHLADVVDKGDHARKRKVLSSAYALKNLETWEHKVSDKVEKVVAH

FDKVCTAAPSAAVASGKVAPDPKDLTVDFRAWTNYFTLDAIADIGLSEKLGFLDQGSDVCIAERKDGSTYTVHLREALYP

TARKQSLILWNYEWYPVLNKLVNVIPFFGRMQKSSDNWDNIVWRRSIERLRRYEAGEKLDDFFQALMEDKNGRANNLEWG

DVVSEVNIMMNAGSVTTAIAIANVMYQLLRNPECLAKLREEIDAVLDADEVVAPYDKVKHLPYLRACLDESLRIFPPTSH

GLPRETPEEGMEILGQWVPGKTTVSMSAYVAHRDERAFPKADQYIPERWLGEEGKALQPYFVAFSAGARSCIGRNISYLE

QTKILATLVHRYEFALPYPGWELKRLETMNLILGDMPVKVWRRQVPATD*

 

>CYP630D3 Aspergillus niger

fgenesh1_pg.C_scaffold_2000776|Aspni1

54% to CYP630D1

MALLLTLTLIILALLIKALLTYLLNTKTITLTKYPPLNPLSNLTTLSYTYEHRHPFRTQRLYNLHRQHNHPIIRLSPTAL

SIADPKAIPAIYGHGTPCLKDDVYALTKGTHTHSNMLNTISRDDHSRKRRMLANAFSTKNLENWEFKIVDKVERLLRQLD

GRCSSSSNGEMDGNEVDLRFWLNLFTIDAIADIGLSVQLGLLDRGSEEVDVDGEVVRYIECLHRGNRVSSWVIGASGWVG

FLRGVSRVVSPYLREQWECGRRFGRVVRSLVEQRVSVQEGRETLSDFLGCLNEDKRGVGRELEKGEIEAEAGLLLDAGSD

TTAIALTNVMYYLIKNPQSLIKLREEVSGAILENGVAPYVKVRNLPYLKACLEESLRLSPPVPRGLERKTPPEGMYILGE

RIPGNFTVSVPTYAVHRDPEIFPDPEAFRPERWLEDDEKIKQMRAVFIPFSSGARACIGRNITFMEQQILVATLVHHYEF

ALPSKDWMLEWEEAFNLWPGRMPVRIWRRDE*

 

>CYP643C1 Aspergillus niger

fgenesh1_pg.C_scaffold_4000279|Aspni1

44% to CYP643B1

MRQAVQLTGADMATLYKYIVEQVAEAPAAKGLSIICCTAAVATLVIVALLKPLYYRTWHPLSRFPGPPAAASSRHWIYRV

TDRGFPEEDLEKLHKKYQTQALRIGPNELHITDVSKYKVIYSQSKPFPKHEEFYEAFNTPHTVFTEIDAGMHKERRRLLN

PFFSRAG VFKLEPIIHDKVDILINKIRRLENSHNINVYDAFR

CLTTEVIMEFAFARSASMLEESETTFESWFLVAFDAVA

RSLWKMQEWPIARKALGVMPVNVIGLLDSNIVNVLKMLKFAESCLKHYEEHGNTTSHPVVFENLSSLPHDLKVTEAVDIF

IAGADTTASTLTAGFMHILSNPAIYAKLADALRGMDITSNDPSAAQLQELEKIPYLTACVKESLRIAMPVPGRLPRVVPQ

DLAEPFVVDGQVIPPGTIVSMSTYTMHTNEEVWGPDARVFNPDRWLQPGAKSLEQYLCTFSKGARMCIGQ

NVAYAEVTIVMAYLFRNFDIQLPPGFRAPEKKDLFTMEYSKPGLPLRFSSLKAK*

 

>CYP646A3 Aspergillus niger

fgenesh1_pg.C_scaffold_3000278|Aspni1

66% to CYP646A2

MFLSISIASWLVIGIIGVGLCLVVKLFETSSVPNGIPRVLNREDLVGRAVERFVGVNPIGFIREGYQKYSKHQKPFVLPS

VAEGDEVLLPKDLAKHVLFSKENEYSFKAYITDFFQLKYTSWPLAFAKKYDFYVKLISKDLTETLKTDSVARSLAEEARS

CLADLWGEDSETWVDISLYCAMEKMASRMINVLAIGPGHSDETLLNAMAHCSDAIVFGASIIKAFPSFLHPIIGPIVGMI

NRYFEVIFHKRMKPIIESKIKEQQKQRDPEAQEETLKSVDSLLDLLIRAGLRSKWPIEATSMWLSYRIFMINFPGVHTTA

VSATSVLLDILSDPIDENLVNHLRAEIESIAGNSSGYWNAEDLERAALLDSAVKESLRLNGINAASPTRKVVAPNGVSLA

NGLFLPCGTKVGIPQYALHRDEEIYPEADRYNPYRFYIENASESAIRQSSMTTTSDEYVVFGHGRRQCPGRFIFAHIVKV

FIAEMLLNYDVQPILVRPKIHRWGRFQLPPLTTKLTVRRKKRN*

 

>CYP657B5 Aspergillus niger

estExt_GeneWisePlus.C_50091|Aspni1

Supercontig 5: 118325-119770 (+) strand

60% to CYP657B1, no introns

note name typo: called CYP675B2

WPAIVAILVSICVVTRLITEFQSRPRGISEGRPRPVRTVPYWLPWLGHGPA

FAWDHVDLLQKSRFSMKEAVFGIYMGGTKHDIVVSPSMVNSVLTARGTSSTDLINYALEKIFGDRGVIRNLNPVDHHTLN

HNIPNLLMREPFLTEGTRNATRLIEREIPNLVTNCRSIVDQMLWERGSQAIVVDGEDSLACEVNFFALIRRFVGHVTTAI

FMGEAILEAFPALLEDVFTLDNQFVLLSMGIPRLAHPGVSAAHVARRRLLDSLTAYHQAFVSWDDGIDPGLTFRDLDDIS

EPIKERIRKCKELGLSARSSAPAHLSLLWAMNGNSPNVVFWHLLRMYASPTLLEEIRKEVAPYVKIVRQESGFAFLEAPK

LSIDTEALVKSCPLLKASFYETLRLHSAPLSFRGVTADLTITESAEDAAIAGVAQPRSYELKRGDTVAIPHAVLHTDPKY

FANPRDFDPMRFISTDSETGQRKANVHTIKPFGGGVSGCKGRAFAERKLLAFAAAIITMWDVKPAQEGGFTVPEHRPSGA

AYLPRKDVRVRITQRA*

 

>CYP660A2 Aspergillus niger

fgenesh1_pm.C_scaffold_22000016|Aspni1

53% to CYP660A1

MLDFYTRLAVLGLLAVFGYAFTRREKPDPREPPLVRSSIPVVGHLLGFLWYGLSYFTMMTEKHAYPIFGLNMIFTKSYLV

TSPSILQSIQRNKKSLSFDPFLSMAAERMVGIRGPTLELMREKQSGGQGLKQAVIHAMQPTLIGASLDRMNERMARLLRP

LVDDLASTSTVDLYGWCRHAITVASTNAS YGPLNPYQDAKIEESFW SFESHLSPLMANFLPWLTARTAWRGREAVVAGLV

RYYEQGGHEDGSEMTQVRWKTMREAGVATEEIAREEVGMGIGLLSNTVPAAFWVLYELYSRPDLLEEIREEIRRNALRVD

ADQRHII DISAIRDNCPLVVSSFQEI LRVQSASAPTRFVMEDVMLADQYFLKAGSMINMPAATLGRMPEAWGETAREFDA

RRYMRSDEKNPRRTGGFMTFGVSPVICPGRHFASSEILGLAALLVLRYDIAPVDGQWRTPRLNSMAVASNMRPLKDEFPV

TVRPRSEYAGVQWDCTVQPGSGVFNLMVG*

 

>CYP663B1 Aspergillus niger

e_gw1.10.193.1|Aspni1

43% to CYP663A1

MPTILLTLLALLTLRLLYEYKRDRNLPPGPRRLPLIGNLHQAPQTLPWRVFDQWSKTYGPIMSAQFGRQTLVLITSPTIA

RDLLDKRGSIYADRPDLVMANNITKGLHMLIRQYDDWLRLHQRLDAPLLSPRASNTYHPIQDLESKQLMFDLLRSNDFDA

HFERYSGSLMFALAYGFRLLSPKGQELRDMRTIQGNFTYAARVGTWIVDAIPVLNYLPAVVATWKRLAEKLFKLEASVHT

RHLEKGLNSEPWNWSKEFAASKHAEGMPRLDLAYNLGILVDAGFETTWAVMKIFVLAIRSDSRFVAVARKELDEVVGEDR

MPTFEDQEKLVYIQAVVDETLRWRSMAPGGIPHATRKEDTYMGYRIPKGATVIPLFWSMSLTDEPWDDPLEFRPERWFEA

TEKEEGRFRNFFGYGRRICTGRHIARNSLFLLMARILWAFDIQAPLGDDGKPVPVDDMAFDSAFVSTPEPFEALFVPRSE

KTKEIVEREWNEMEKDMAVLMGQVRESQR

 

>CYP666B2 Aspergillus niger

fgenesh1_pg.C_scaffold_12000110|Aspni1

59% to CYP666B1

MIAYTLVLGFIGLVVFDYIWNLAQNIRKAQRTKLPYVASPYNVSIIFIILFGWLLPLLAEYCLPQWMGDLLYDNVGTYRW

TVRNRQVKRYGKVYILVNPRGVFCSVADASVVCQIVNARQDFPKPNNALVWEESIQQTQDMIAQWAEASPLDSTRGSGFT

VESTRDDIHKLTLNVLSGAGFGVKAPFKLLPQESLKNPEDIFRDSPTPPTGFDFTFRSVVAYMNLHIPTMALANNMLPKW

VPRPLVPFFKQDFAAHRDLDKYLQRLITTTESRLSGEENPSNLIEGMLISRKPGDAKDAGLSDREIISNMHLFTIAGHET

TATTLRFALVLLALHQNVQDWVHNGIAEATKDKLPNIEDWNYDDAFPKFVTPLCVMLETMRLYPPVITIPKFTGDSPSVI

HYDGKDYVLEPGTYINLNTNGLHYSEEYWGDDATLFQPQRWDARNKGSFLARNTDLPGLAGPGLEYPTIHKPVRGAYIPF

SDGFRACLGKKFSQVEFVAALTTVLRQYRIELADSSEKGRINAERVLNQSTSIITLAMGEEVPLLFRRR*

 

>CYP669A3 Aspergillus niger

e_gw1.4.1307.1|Aspni1

65% to CYP669A1P

MSTAIRQYHHRIIRKVEKLVNLIQAEGHRPILINEVMYWFAFDSMGDFAFSMDFKMMENQEWHQVILLFRSALALLGPLS

PAIWIPRLAFAFAPGLLWAKWWFQMLAFCDQCMERRMKQTLKDKDIASFFIEDHSTSTDKRRKMWLSGDTATLVVAGMGL

SKLSHLNGAINETMRLLPAVLTFGTRVTPPEGLTIADTFIPGGTKICAPRYTIGRLESAYERPKEFIPERWYSQEELIRD

RRAFAPFGVGNTSCVGKNLALTQIRLVAAALVIRYRISFAARNPDGERVEGEMKDQLTAQPGPCWLEFSPRDD*

 

>CYP671B3 Aspergillus niger

fgenesh1_pg.C_scaffold_9000394|Aspni1

65% to CYP671B1

MQLSSSVVSLADIRAVLESDLLSLAASAAGFGLLSHVSLFRTNFPVEDYLFILLALYAVAVLSTAYAYLTLTQFSVAQAL

LRVILISSAFNTGLISSIGIYRLFFHRLHHFPGPVGAKISRFYNAYLAGKDLQYNVEIARLHHEYGDFIRTGPREVCIVR

KSAIPLLFGPQSKCNKSTWYAHVSTNPKYCSVHCTRDHDDHRKRRKAWDQGFSIKALGIYEPRVKSKADLLASHVAKNLG

QPIDVTAWTMFLSFDIMGDVGFGKDFHNLTTGVEHPAIKGVHDHMAAGATLLQVPWLLNILCRIPGAVSGYSSFFKWCAD

EIERKQKTWDANAYPEDVVSWLLKAYVERSVSAAPSRMALNEDSRAVIIAGSETTATTLATVLYYLAKHPSVLAKLHQKL

DEAMPGGADDWGYDKVKDITFIDDIINETLRLRPAVMTGGYRVTPAEGLQVDEVHIPGDTIVFVPVQLIQTDERYYESAK

EFIPERWSEKRYEMKTDGAPFIPFLTGPYICPGKNLAMISLRTSISTIAQQYNFSFAPGETGEAFETGAQDTFTTSLPPL

QLAFQRRQK*

 

>CYP671E1 Aspergillus niger

gw1.5.1493.1|Aspni1

43% to 671C1

WLDVALLTGLFGNIVVYRLFFHRLRNMPGPIAARVSRHYAAYHTIKDAQMHYTVQRLHQQYGDVVRIGPREVSVCRASAI

RAIYGPPSRCIKGPWYDQVTNENDKKPLFTIRDPRVHSKRRRQWDQAAKGINHYHNALQKQSRILIEKIREHQGRPMDVT

NWINCYTFDVMGHIVLGAELGMLKTGKKIPELQVIDEGQRYIAVAGTMPWFPPLMLGIPGLSAILNPFRHHCHKLFDAKR

AAMTKGSEPKDIISWLIQAQDNGDPGAPPTDQAIKDDAWFIIAAGSDTTASALINAVYYLATHPGAQAQLQREIDERLPE

GIEGLSYENVKDLPYLTAVINETLRLKPSVLDGLVRVTPPQGLKVDEDLHLPGDVVVSVPTFAIQRDGRYWEDADQFRPE

RWASIENPANMPFIPFSRGSYDCVGKSIAWMEMRMALAMLVGEYHIQLSDEEQRAFDGKELDNFAMSVPALWATFRPR

 

>CYP672A3 Aspergillus niger

fgenesh1_pg.C_scaffold_20000080|Aspni1

75% to CYP672A2

MVFAMALPSGQMPEINPSNLSLPVMAVVIIATKFNFVTGRSAHYFNSLHVSYGKVVRFAPGQATTNTIKGLRNIYGAGSG

KGSTFLKTGFYKGISRRNIFTASDPVYHASVRKLFNPSMTPSSMQAHANVVLECTSRLHDVINATLKSTDTISLNRLLYC

HSVDTVSEVLLGKSLGCLKRGKPYFWTEQLSRIFFWATIRDQFAGSGVPTMIKMMLRYLIRKGVRSRAEQARMRLINEQL

TASHNRRDIMVEVMERAATSDLPVDEIAENFSAIMLAGFHTTQNALCATIYFVLTHPEAHAKLISELQTAFASPEDVSGD

VAANLPYLNAIITESLRLYPPVPLGGPRVSPGAYVDGTYIPAGTEICTSLFALHHNPEYFNEPYEFIPERWTDPESTDKK

EAVQPFLVGSRSCVAKYFAKQMMQLTLASFFLEYEAEYIGPVKDWQRESRCYAFWEVPDLKLKLRKREAI*

 

>CYP673C2 Aspergillus niger

e_gw1.1.1529.1|Aspni1

70% to CYP673C1

MTVFIQTITSTPMTSAGLFLALILIVYSIYQRYLHPLAKYPGPFLACLTDLWQVYQFLTLKQPYNLTELHAKYGPIVRYG

PDKLSITHEGAIQAIYQKGGRGMPKTECYDAYGAAHPNVFGMRDEEQHSIRRRHMSHGFSMSYVKEMEQYLDVNIRILRD

KIREHSSHNRAFDLKKALHYYVVDVLGELAFSQSFGIQETDDEARVPPVIEHSLLAAVTGAWPAMTTTLKKYFPLVPYKP

LQQLFAGRKACADLASECVRRRLGDFGGNGMSKSDDRKDILTNLISAKHPDTGKHLTQTDLETEAFGFIIAGTHTTSATT

TLLFYHLLHNPRYMEECVKEIETNLPPLTYGETAYSVSAAEAALPFLRNCIRENFRITPVFTMPLARRVMRPTGVMIDGQ

HIPQGTSIAVCNHAFHHNPDVWGDDHNIFNPYRWENTEIAAKARLLMHFGLGGRQCIGKTIAMTNIYKIMSTLLREFNFE

LADKQAQRNGMPELISVGISDLKEPLMVRAHVRVQEKVEWAHNL*

 

>CYP676A2 Aspergillus niger

gw1.2.1506.1|Aspni1

62% to CYP676A1, revised 2/10/2009

XP_001399153.1

MPVLFASAWLPGSLTSLPVSLPFLLFVFVVAIAVKRRYATSIRDIPGPWLASISSLWQVYQLIKGHTEQEIVKLHRRY (1)

GSFVR

IADNEVSVAHPDAVRLLLHANIAKGSWYSIFSLPDYHYVNQMSELDPQRHIRKSRNVASGYALSNIIKSEPFVDALLGLL

EEQFDKLIASGQPVEFDRWFNYFAFDVVGEVTFSSPFRFLETGTDIRNAIANTRALALYIAIMGHYVWLHNLTLGNPLLS

RIGLQPSSHIFDTCLAAIDSRKKNPDVRLDMMERWLHVRREYPDRMDEAEVFGAAVANIGAGADTTSATLQAFFYYLLRH

PQYLQKLRQEVDEAHTRGDLSHVVSYAEAAKLPYLQACIKETYRYHPATGTGLPRVVPAGGLTIGGRHFTEGTLLSINPW

AFHRNPDLFGPDCDDFNPERWLDPDRARQMDPFLIHWGAGYNQCPGRNLAHFEISKVTATILRDYDIEQVDPKKPWSFET

HFTAVPYGWPCWLRRRQPAA*

 

>CYP680A3 Aspergillus niger

e_gw1.1.1307.1|Aspni1

63% to CYP680A1

MISVHVLLLTVSVLSIVLLLRCVWTIAYRLFFHPLAHLPGPLLARATHLYAFWYNMQGGSFYLQVQKLHEQYGPVVRITP

DEIHLSDPENCEKIYYIGSRYGKDPQFYGAFGTHKATFTAPSPDVHRVKRSALNPFFSRKKVLELEDIVQDKADKLVRRM

RESFSSTGCIDLHHAFRAISVDVISDYAFGNCYGFLGKKNFGAEFFEMIRGFGPAFWFFQQFPAIQGLSLGTPFWLAKLT

SEPLTRMMLHREGSRRQILKVKDAVDRGEKGSRTTIFHQLLHPEAAEGHVVPTVEELEDEAYIMLAAAADTTGNALTIAA

YNVVRNAKIYKRLTEELKQAFHDSEAQIDFVALERLPYLTAVIKEALRLSCGVPGRLPRVVPDVGAEFNGYHVPPGVCNK

HGTIIVNFANIFLDCSSLSRSTCSLSARGLDNVSGCRICTDFCRLAYCELYVTLGRLFRQFDNLKTAQKSREELRYNDYF

SSYHPAEYNK

 

>CYP680A4 Aspergillus niger

fgenesh1_pg.C_scaffold_71000001|Aspni1

67% to CYP680A1 aa 316-512 seq gap upstream

PFWLAKLTSEPLTRMMLHRE (0)

GSRRQILKVKDAVDRGEKGSRTTIFHQLLHPEAAEGHVVPTVEELEDEAYIMLAAAADTTGNALTIAAYNVVRNAKIYKRLTEELKQAFHDSEAQIDFVALERLPYL (0)

TAVIKEALR (2)

LSCGVPGRLPRVVPDVGAEFNGYHVPPG

TVVSMSSWTMHHNEELFPKSETFDPNRWTDPVMSKSLEKYLFSFGKGSRQCIGMPLAYCELYVTLGRLFRQFDNLKTAQK

SREELRYNDYFSSYHPAEYNKFIFEKAS*

 

>CYP682F1  Aspergillus niger

          XM_001397274

          43% to 682C2, 42% to 682D2, 41% to 682D1

          35% to cytochrome P450 Myrothecium roridum tri4 gene CYP58A2

          60% to DQ054596 mid region fragment of Aspergillus ochraceus in

          ochratoxin synthesis

MSIDTLLYTSLAVGAVYLASVALYELYWSPLAHIPGPKLAACTR

LYEFFYDVVCGGQYTFKIADLHKQYGPIIRISPREIHIHDPNYYETLYATNSPRNKDP

WFTAHFGVDESAFSTLDYRLHRSRRAMIAPFFAKARMDGAQPLIKANLAKLIRHLDAH

ASSQSVLKVEVAYNSFTGDVITGYTSYRSFEYLETTDMVPIWSETVRNLVESGMLSRH

LPGFFPLLAWAGSRCIAAVYPKLLPVIAFRMKCAQEVNFMWTNSEEGKKEAIQSGCSE

PALFPELVSRASSAPDITEERLLHEFITIVAAGTETTAHTMTVCTFHIAHNQSILDKL

REELDNRFHSNADMDLQTLEQLPYLTGIIYEGLRLSYGLSHRLQRISPIDPLKYKDIA

IPPNTPVGMSSALMHHDESIFPQSHEFIPERWTDPNDRRRLNKYMVSFSKGSRQCIGM

NLAFAELYLGIATLFRRYDMKLHDTTLDDVQLHGDKMLPRAKNGSKGVRVTLRRAQSVG

 

>CYP682G1 Aspergillus niger

e_gw1.2.437.1|Aspni1

44% to CYP682B1

MTLFGELSYLSLASITLTVFLAYVIGCIVYRLYLSPIAAFPGPPLAAVTWYYEFYYDAICGGRYIFKIKDMHKRYGPIVR

INPEELHIETSTFYDELYAPGGKKRRNLNPQFEHQFGAPNSTFATVDHDLHRMRRSALSPFFSKASVRRLQPVIWEKVDK

LLRRLDEFKNTGQPVRMDIAYAAFTNDVDVIMEYSFNHSRDRLQKPDFGEPAQEAVLAMSKVVHWMKHYHWLIYLAQLIP

PWIVSWISPTLQSFTRENVAQVHQIMNDKDRLGVGKQSKTIFHDLLANPDLPVSEKSVEQLGQEAKILVAGGTETTSWTL

SVITYYLLSQPHTLSRLRAELIASIPDPTASVGIEVLEHLPYLTAVIQEGLRLSYGSVGRLARVSPDEAVTFHDEKRAKD

WIIPPGTPMSMNSVFVHHDPTIFPEPSKFSPERWIEAEKEGKRLNRYLVSFTKGSRSCVGINLAYAELYICVSRIFRLYS

CTEDEMSGKGGWLELFETSNEDVEFATDMFIPATRQGSKGVRMLVKGI*

 

>CYP684A3 Aspergillus niger

e_gw1.8.1151.1|Aspni1

66% to CYP684A2

NPLSSIPGPFLCKWTDIFVRYQTVTGNRPRYVQALHKIYGPVVRVGPNAVDIAKIAEAREIHRIGSGFLKSPVYELLKHD

NAKSIFSTTDPKFHSKHRRLLSSPFADANLHSLEPLIEARIRLTMQRMREEMTTRKVADVQKWFFFMSSDIIGELSFGDS

FRMLEQGKKDQHIKDLEIAALVGESRVAFPFIFRLAEFLPLPILREANKSRNRFGNYADECVNRYKRLLAASPEDVKPTL

FTKLYNAGKEGLSDAEIRDDASDLIIAGSDTTANTLTYLTWAVCKAPVIRQALVAEVATLPERFSDKDVQSLSYLNQVID

EALRLYPAVPCALPRVVPPQGATFSDHWVPGGSTVTTQIWSLHRDPVAFPEPEKFDPSRWASPTKEMKDAFMPFGAGTRN

CLGLHLARIELRLATAHFFRQFPRSEVSSREGMSDEDMEQVLHFLLSTKGHRCLLEV

 

>CYP684C1 Aspergillus niger

fgenesh1_pg.C_scaffold_11000386|Aspni1

44% to CYP684A2

MESLAQLPGIFLPLAGCVLALSLSALLAVGPIVRVTPTEVDICDLPAVREIHRVRGGYLKSEWYKSLTPPGVTSLLTLIE

PTQYSEWRRLLAGPLSDTSLGKVEPMVTNHVHATIDRIASDLQSQGVSDLYKWWTYMATDVVSELSFGEPIGLLARPKET

AWVMDYLDKVGIMHAWRTTFPFVFVLGRFMPVHPFKHAIQAIGLLGKWARRSIQQYRQHIQEQPESPKPTLFTKLFKADK

FDDFQLTYLAGSYITAGSHTTAVTLLYLIYAICRDNEIRQKLLAEIRTLPENFRHDELRHLPYLNQVITETLRKYAVVSS

ALPRVVPAGGATLAGYYLPGGTTVSTQAYTLHRNEAIFPNPEKYKPNPKYSYLSMLSVWLIECRFDPSRWESPTQEMKDA

YMPFGGASRMCIGNSLALMEIRLTTTLFLRRFPEVQMSRQNGMRDEDLAQEQYLIMAPRGHRLLVEA*

 

>CYP5042A4 Aspergillus niger

fgenesh1_pg.C_scaffold_8000113|Aspni1

82% to CYP5042A2

MSKSVHAQISGIAREYPFSATLVTIAAFLATIFLVIREIFTPVGKRRPPPGKRCKLPPGPRGIPIFGSLLDVRKVRDDQD

HIINNDLAKYGEMTTLHLGSKTWILLNSKRVVSEIIAKRGTLTNGRSPMPIASGIVSRNGRSLLLPPSGWTEKRRVMHSL

LSGTALKQYASWQELESTQLLAEYLFQPERWYRHHYRYANSVVHRIALGERLVKSGKELEDLQNVVTYFVGSIGSSLIDW

FPELDRLPRALQPWRKHWEKLGNWNEEVYKSWWIPVRDKVEQGTAPPSWVRDVLLHPDTKFTGDDQEAMYVAMQLLEAGS

DTTREVLNIFVMAALCYPRVFQKAREEVDRLCCTEGGLRLPGIEDLEHMPYICALIKELLRWRPIFVLTPDHVLTSDMEF

EGYHFPAGVGFVINEVPVCNECEDPEEFKPERWLDGHETDAAHGLWQFGGGRRICVGYRLAFRGLFINVARLVFCYNYAA

AGPYNPKRLNHHKTDEPFPVKVTPRSEDHVNLILREGESLQVLEDAKRRV*

 

>CYP5054A2 Aspergillus niger

e_gw1.6.818.1|Aspni1

63% to CYP5054A1

MVALLDYYWPFNLVIVSVVAAGVLTIAILSYLRYLYVDFPSIQGIPEIPGGEILAGHLYQLGNDHATTAERWSLKFGWPV

FQIRMGHRRAVVINSFNAARDWMIKNQSATLDRPSFYTFHKVVSATSAATIGTSPWNERTKKQRRVVGSLTTGPAIQKLR

PMLDLETFSMVSGIYNDSENGRIGIVPHIYQKRLALNIMMMFCYGTRFESITDPLLLQILEDASTIASFRSTNSNPQDFI

PYLRYWRKEGRTATALEVRERRDKWLATMLDGARESIRLRTGDRKCVAKLLLTDEQEGLTKLDVKTILGGLMSGGFETVF

STAIIAIGVLSTPQGQYIQERAYADILNVYKSSEDAFELCVSEEKCAYISSIVKETLRFYPPLKLLPARQSFKEFMYQEA

VIPEGVLIYLNAQAANHQTVYGPDADEFRPDRWLKAEHDIPPPYHFAFGAGSRMCTAVKFSNRVLYATILRLIVSFRIVE

EEECPPNTHYVHYKRDPTASNAIASDFKVRFIPRDENALQRMFERSQELCAATIAETAGTVMGIP*

 

>CYP5055A3 Aspergillus niger

fgenesh1_pg.C_scaffold_2000945|Aspni1

56% to CYP5055A1

MLYLVLALSVPGYLIALTCYNLFFHPLRSFPGPPLAKVSKLWSRIGNRTGRKSDRIHEAHLKYGPVNPPPREPYIHRMHW

SDSMCASHVLIVPRDVQAHRQRRKFFARGYSQAAMLEFEPHISNKIDMVLKQWKARLVDGPIDVYPWLHWLAFDVVYHLM

FDDDPGQVTSGRSHEVMAYLQAWKPTYIYKEFFPQLDRWGVYVPGYVGDYFRKVQAWKNYSVNLIQRSRERGTKTPFLRS

ALNGDEDAFLGRPLTNSELAEECMGGMFAGSGTTANTFAFLLWACLRKPDVVARLKAELREAFPDPSIVPDHRTCSALPY

LQAVISEAFRRYPAAIAILPRTAVRDTTIAGVPISKGTVVGAQNRTVHFDEKAFPDAQDFRPERWLEKENEALRKEALAP

FSLGPRKCVGLNLAQMELNKLTAAFFRRFDGEVDGSMGEEDMRMYDTFTASPAGGRLLVRLRESV*

 

>CYP5061B6 Aspergillus niger

fgenesh1_pg.C_scaffold_4000153|Aspni1

73% to CYP5061B1

MAVILEVLDNQHLLQGVVLALVLVFVSSFYHEIADSFPYKNIPLVGKGKWEITNTKAKHRFVTSAKELFAEGFSQGRKAF

QVHFSARPTIVLHPSLTNEVKNNPLLDFNEANKKSFFGSKIPGFEPFDGLDHEGIFLEVINKKITQGLGQLTTPLSRETI

AVLNEKLPDSGEWLPFTFAQEIPHIVARLSSLVFLGEKICRDKQWLDVSVNYTIHAFVAARDLRLYPTVLRPFVHWFLSS

TRRTRQDIRVASAIINREVEKRKLIREGKLPEEDPPRTHADTLDWFEEVAAGRPLDLAVAQVGLSLAAIYTTSNLLTNIM

YDLTAYPEHIQPLRDEIKAIISEDGGLKKTSLTKMKMMDSVLKESQRMHPAGVAFINRVAMGDITLSDGTRIPKGASIAV

SAHNMEDESLYPNAKTYDGFRFYKKRQEPGNEHRFQFVTTSPEHLGFGHGMHACPGRFFASNEVKILLIHFLMRYDWKFA

DGRTTRPMNFMHGTESICDPTVEFLFKPRQPEVDLS*

 

>CYP5061B7 Aspergillus niger

fgenesh1_pg.C_scaffold_15000297|Aspni1

52% to CYP5061B3

MSRWFLFDRHANVCFMASARALIREGFEQVVPSWTYLSFGLIRWDTARIGPHDVPSNVSPRPYYVDEVRRHPSLSLEEAV

KESLPVGDYPGFEAFRGTENHHILLDVINQKITRNLKQYTIPLARETELTLDEHFGQPQEWKSYCFASEVPYIVARLSTL

VFLGEQVCRDTEWLDISVNYTLDIFGAITALRGWPPILRPVVHWFLEPAQKLRKRVQVARRIVQREMRRRQHEHKPRQPD

ALDWLHEVAGGRHLDVTTAQIGLTLVTIHTTSNLLTNVIYDLAANPQYLPPLREEIQSVLETDGTFHKTSLTKMKLLDSV

VKESQRLNPPGLTSLHRYAMEEITLSDATVIPKGASLVVSAHTMQDESIYLNAHTYDGYRFYRKRQEPGHENKHQLVMTS

AEHYGFGHGVRACPGRFFATNEIKILLAHIILKYDIRFPDGQSRPANWEIGQDLVCDQTVQVLFRAR*

 

>CYP5063A3 Aspergillus niger

e_gw1.8.180.1|Aspni1

70% to CYP5063A2

MIANLAIVVVFSIGVITLLYVITSHQPNRRAATDEKRPPLKLPLIGDLHSSPIDKPLANWDDWARQNGPITVSKLFGIVP

IVVLNSYEAATELFSRRSQWYSNRPRSATMEMITGAKPGQSRFTLMHDYDDYLRLHHRLLAPSLGALAAPRYQPLMELEN

NQLLCDLCDALHGCPDGATISTATIYPLLERTQSSIILGLHYGLRILHPEDDLLQEIIGTQAQVTHLAANPGLPDLIPTL

RQLPGFLSPWKRAADELFATQSNLYMRLFHRGRDSDSWNATKQALATAERYTAVPDLDLAFTLATSIQGGMETSPRQMLW

LFIAMLHRPSVLSRAHAVLDAVVGRSRAPRFSDRPKLVYIDAIAHELFRWRPISPGSIPRRADRDDEFQGVKISQGVTIM

ANAWAVGRDAQIFNSALGDLPDFVPDRWLLQGNPHNAEAQLRSDLPLPVFGQGRRICQGKRIATDGAFLQVANLLWAFDI

MSAEGEEMDPWAMTVVGFMTMPKELKMRLKPRGDWVMEAIKREPKIGSEDLDQVMGSVNDVE

 

>CYP5068C1 Aspergillus niger

e_gw1.19.56.1|Aspni1

40% to CYP5068B1

MDKHLNLFVFISIFASFLLVTYSLVSKKRNHNLPDGPRPLPIIGNIHQMLSQRLMEVVHKWHQDYGTMVAFRYGQQQAIS

ISSFEIIQDLLVKRGAIYSSRPPFIIASRMSLGFNSAIMPYGKQWQNHHRIMSSFLDTTAVGRYRSLEDMESKQALAELL

ESDDFEASLSRYAGSILMTLGYGIRLETTDNDIPAKLHAMNRHPFEAMGNTYYSLVELFPVLDKLPSCLAPWKQFSANVE

REAAEFHMEHFEIGKSASTWNWVQNALHSSAGSRVSSKELAYVIGTLQQAGFEATLTILRLVVKTIVLHPHCLREAQQEL

DRVVGPDRLPSFGDIPQLSYINAILNEAMRWQTPIPFAIPRTTTQDDEYKGYHIPSGTVIIPNVWAMMLNPEVFPDQDKF

KPERWIENPNLDHSPFGFGRRICPGRHLGWDSVFILTARLLWAYNITHSYKDGKRIEIDPRDIELTFTAAPRPFKASFQV

RGSKRQEIIE

 

>CYP5075A2 Aspergillus niger

estExt_GeneWisePlus.C_90633|Aspni1

72% to CYP5075A1

MILEALGLLALAYLAWSMVTMEINYRRASSMGIPLVRLYIDPQNVLWMVFEPIIWPWLNKLPINWRNYSFGRYSRRGWYF

ADRGESHKRYGPMWALVTPRDIYINVADPNAIHDIFQRRTDFIRPSQMYKVLEVYGPCISTASWNDWPRHRKVLATPFNE

NAMSFVWDESVEQTRQMLQVWGSSADGHIPSVAKDPRTLSLNVLAATGFRKSFPFQSAKDHQVKSKSPATSEDESEGYRD

ALQTVLDNCILLMVMPRKLLTLPFAPESWHHLGKAAADFKNYMVQMLNEETKALNTGSAGSGGLMTSFVRAMDLKQKVDG

EGKTKTSGSPPKGLTVDEIFGNIFVINFAGHDTTANTLSFGLLLLAAYPEVQDWVAEELDGLDEDNIKEHYGELFPRLLR

CRAVLLETLRLFPPIVSLPKWTNDEPQSLRLGERDIMIPPHVGVHPSLLDMHIHPQYWEDPLTWKPSRWITKSASGDASE

AIITPSRSTYFPWSDGPQNCPGNKFSQVEFVAVMAALLRSHRVHPVANPGESPKETRARVLATTQDVDLQLLLRMTNADQ

VRLACSRVA*

 

>CYP5076A2 Aspergillus niger

estExt_GeneWisePlus.C_200209|Aspni1

51% to CYP5076A1 (ferricrocin hydroxylase?, check for NRPS neighbor)

MVSSMLTAALVGVFSHLTYFRRGEHQLYGTTYTQVFGVLNATAVAYLHVSWGIAWQEALVTVSLHAASYLLGIFSSLLLY

RLAFHPLGAFPGPWPARISDLWLCSQMKNNNRHIKLTELHEKYGPYVRIGPSTLSVIDPKAVNIIHGPSSRCLKSGWYDH

SHPNKSLQTSRDPAEHQQRRRLWSTAFGSKQLRGYEHRVRKYRQQLVDRFVEREGQPVDVTKWFDLYTYDVMGDLAFGEG

FGCLEQGEYHWATQIMMETMDFVGSNLPMWLFRMVLEVPGLKSGWYKFLDYCETRLVERMRNEPDVPDISAALLAPFKGK

EPGKEDQQWLGGDSRLIIVAGSDTTASTLVSLFYELCHHPDEVEKLRAELAPVVNEHGRLGDFYDSDIGHLAHLNGAINE

AMRLYPAVPSGVQRIMPPEGITVDGVSIPGNTTVINPVLAMGRSELSYKKPLEFIPERWYQQPELINDQSAFVPFNIGTY

NCIGKPLALQNLRATVAHLVTTFNVKFAPGNAEKDLIQRSKDCFVLYHGELDLIFTRRK

 

>CYP5076C3 Aspergillus niger

fgenesh1_pg.C_scaffold_5000548|Aspni1

57% to CYP5076C1

MSLFRFPLLSLRVLPLLHKICSDSCDMNLENGLQLKAGAFVLGVLAHSVYFRSGEHHLHPVRYLYAYGSLGILVAAILYY

AHNISLTRASTASLSLISTHLLGLYCSLIIYRALLHPLRRFPGPFGARLFGFWLPAKLFHRPLYQVLADLHKYYGPFVRI

GPSDLSIIHPDAVNIIYGFRSACTKAPFYDLGAPVQSLHAHRDKEAHDQRRSVWSLGFSDKSLRAYEKRIQVYRQKLIDL

LTSAGDDEAINISNYLTWYSYDVMGDLAFGRTFGMLDASANHWAIQILNDMLKPLEYSVPIWALRLLGSLPGMNEDALRY

EEFSHRRLKRRMGEKPEIPDISSSLLEELQGRDPTTKEYYQLLGDVELIIAAGSDTTAAALITVIYELAKHPVHVDIIRE

ELSLCAVEPSGEYMHEKIAGLSHLNGFINEVLRLHPPIGSIIPRKTPSEGITIGDTYIPGNMTVSCPQWVIGRSDLFYEN

AHQLLPERWYKYPEAMKHKSAYAPFSVGPYACIGKPLALINMRTTVARIIMAFDLQLPLDDVGTLLDKNMKEHFSSYVEG

IYIIFRKRSRNFQTD*

 

>CYP5076E1 Aspergillus niger

fgenesh1_pm.C_scaffold_3000040|Aspni1

44% to CYP5076C2

MILGSHLMLFAAGALSYHLFFKHEEHHLRIVRYIQVLAATFLGMVVCFQHGYRLDFSSSLTQAARIQGSFLSGYYTSILI

YRMFFHHLNFFFSVIFRHSDGFRQVQRLHDQYGPFVRLRPNYLSIAHPKAVNVIYGLGSRCMKADWYDISCPMVSLQTLR

DRKAHDERRRVWSAAFGDKAVRGYEQRLLPYLNHLMAYFSSQAVANKPVNVIKWFELYSYDFMGNLTFGKSFGMLEAHQD

HWAIDSLKKVMIPLGFAFPTWFFRVVISIPGLSRAWQRLFDFCGQRMLERIKTPAEIPDIASVLVAPLKGQQPSQEQWEL

LRGDAQLVVLAGGDTTATTLSAAVYQLVQHPEQVQRLRDEVSPYIAGPSHEVLHEKIANLPHLNAIINETLRLHPPAATA

LQRKTPPEGIIVDGVHIPGNMTVMCPQNVLGRSEAVYERPMEFLPERWYLQPELVKDKSAFVPFSIGPYGCIGKPLALLT

IRNTLVRLVTMFNFEYAHGEDGMAFEGKAKDRFTMSFGDLQILFSERSDM*

 

>CYP5080D2P Aspergillus niger

gw1.11.656.1|Aspni1

52% to CYP5080D1, frameshift and deletion before PERW

AIPGPLWSRLTNLWYLRQMVKGDFHNTNIKLHRQKGTIVRIAPNYYSLSDPACLKTIYGLGTKYVKSSWYDAWNTEEDLT

WTNLFSERDPKKHAANRHKVASMYSMTTLTSYEPFVDSCIGLFRRQLDQAGSSDSAVNLAHWVQCYAFDVIGYITFGERF

GFLDNMLDVSNIMKNLDAAISAATYIGLFIMLRPLIMKILRLMGLLGTDALADFAERNVKMGGSRKATYGAESIGSYSPM

LNKLLEAKKAAPGKFTEWDIMANVISNVGAGSDTTAISLSAVFYFIYSNPETLQRLRDEINVAGIDGIPRFSDTQSLPYF

QAVLKECLRLHPGTGFPMFREVPEGGAVISGQFFP

XXXXXXXXXXXXXXXXXXXXXXXXXX

RPERWLHASEAEKALMERSYMPFGMGSRTCIG

KNISLEMNKLIPLVVREYDVEILGHGQGLKTCNHWFVKPV

 

>CYP5080F1 Aspergillus niger

fgenesh1_pg.C_scaffold_7000061|Aspni1

50% to CYP5080D1

MILAPIPTFSALALGLFLWVFVKRALSSDRDIPGPFLARFTRLWYLRQMTRGDFQYTNIRLHRDHGKIVRIAPGWYSLTG

LDAIKTIYAHGSKFIKSEWYEAWNFSPDTRDHNLFSVQNVADHSSARRKVAAMYAMSAIVSYEPYVDNCIRRLRKKLDST

AKDGSTLDLGHWLQCFAFDTISEITYGERFGFLDNGKDINNLIANLDQSFVISSLVGLLIWLRPLALFLGSFFATSDALY

VARFNAQKFKELSQEYLKNPSPPGLIPMVRRLLHARQEDVKGLTDKDIQTSAASNIGAGSDTTAIGLSSVVFYSYRFPET

LKKLRQEIQDAGLGSEPSFQETQKLPYLQAVIKESMRLHPGVGFPLFRIVPKGGAVICGRFFPEGTNVGVNSWVIHRDES

IWGSNADDFVPERWLTEDSEKLRIMEQCLVPFGIGSRTCIGKNISLYEINKLIPQLVRDYDIDIQQEGGTDVRSNNMWFV

KPVQFDIKIKQRSDGSGV*

 

>CYP5087B2 Aspergillus niger

e_gw1.3.514.1|Aspni1

71% to CYP5087B1

MTALLLSGPSKSNGLLLALAVIAVGVAITLLANNFNQRRRSRQLEQLHGCEKPPNESDRFRYDIFGIAKSIELAYHFRRR

TSLSYTNALFKRYGETYASNVLGFRLLFTCNADNIKHLLSAAFIDFDSSPLRRPLFEPITPHGIFTLDGAAWKTSREQLR

SRLSNLRKAIDLSLCEQHFQDFLRHIPLNGRPFDIQSCAFGLSLDMQTLFSLGESVDALSFTQSQEKKQFFKDLLLVKNR

IVQDGFRGPLRHLVPKRSFLQACKSSRAYVMARVVRDLERQGSVDKEADELPTLESYSDTNRVSQLTDQALSILLANDSM

STTLSGLFYCLAQNERVVHKLRASIIDAIGLTPPTWGQLGTLHYVRWVLQEAMRLFPPVVLNARVANKESTLPTGGGAHG

DKPVLVMKGDIVVFSTWARHRLGKDFGEDPEEFRPERWEQLSGDMAGYIPFNKGPRICPGRK

 

>CYP5089A3 Aspergillus niger

e_gw1.3.357.1|Aspni1

57% to CYP5089A2

MASLIVVIAQLTVLTLASRMVYLCYFHPLAPYPGPFWARCTNLWRFFTFMTGRLHLAEQQLHQKFGPVVRVAPNWLSFSS

LEDFDAIYGFNKSVEKGDFYAFGRSPSQREASIFSTKSDTIHRHKKRKVLGPALSSSKVARYEPVIEEHVAILLARLEAS

RQPAGTAIATANVAPLISRFTLDTMLEILFGSAIASNPYTDSAAAGAICSQLRKMTKRAWSYSLWPIYGRIMNSWAINYL

LRSLFYNGDGAQTGMTGLAAAVHRAIMRDPQHVMQSPKPGIVKSWLEVPVDDVNRMKQPEVLAEAMNMVFAGPGSMAAAL

TAIVYHLGSEEGQVWQDKIRRKGAVSSQSITAATIPLELQAVMKEAMRFQGVFPTAFPRVIMSGAERVIPSLSTPLPVGT

TVSANTYVLSRSREIWGDDADQWIPERWIGDAEHRRQMETKFVAFSKGPRGCVGKDLALIVLAKAVMGLILQWQIISVGS

LRGKSWLEMQYDDCWLELRRLSTAP*

 

>CYP5092A2P Aspergillus niger

fgenesh1_pg.C_scaffold_3000010|Aspni1

41% to CYP5092A1 aa 241-396

MAKQAPEEYNQVGVLGATLTIIGAGSGTTEYLLAFLLRSI V*CPRIKQRLRNELRLAISEGRLPQLPEWAEVSKLQYLGTIVREGLRL

HTPVQSTMNRVIGPGGLDLCSRWIHAGTTVGCFLQAFHLNKDVYGTDAREFGPKRWVEVLEEHVKSMERGGFWFGSGKHV

CLGQHVARMGITKLVASIFMRLENALFMMIGPKKVPEVSPGASLQMSPSVSSRLW*

 

>CYP5095A2 Aspergillus niger

fgenesh1_pg.C_scaffold_15000164|Aspni1

67% to CYP5095A1

MGLIQGLVAGLSSVADSPIALCAVLTATLIVYSVGLGIYRLTFHPLAKFPGPKLAALTYWYETYYEVFKSPGGQFLFQYH

KLHDKYGPIVRISPNEIHIRDASFFEEMFSNSLPWNKPEHLQYRFDNALGTFSTPKHEAHKPRRAALNPFFSKRAITNAT

PMMQDKLYKLCDRLRREYQGTGKVLRLDWMWGCIASDIIVHYCFNDGYGFINAPDFRSVFIQAMFDLLDMVHVLVQFPWV

GVILNRLPQKFVEAVNPGLKSINHYNREMASQITDILRSKEYGTMKESQRKTVFNALLEGGLPPEELTLRRLREEAFTVI

GAGFETTRYALAVASYHILSTPSIYKRLREELITAIPDPTNFPPLSELEKLPYLTGCLQECIRMSYGIVQRSPRVSDKFP

LIYKTWTIPAGTIISMDNYSVSHDEAIFPDSFTFKPERWLDDPVAPDGRKLTRYLVSFGRGTRSCLGINLAYAEMYISLA

NVYRNFEFELFETSRESVDVYRDMFLPHPKPGTQGVRVKVL*

 

>CYP5096B1 Aspergillus niger

e_gw1.2.1500.1|Aspni1

47% to CYP5096A1

MNIPQGLPTLKWSGIVSIGLTRGAFVCLFAIFVVAYVVGLVFYRLCLSPLAKFPGPRLAAATGLYETYYDVIRDGQFTWH

IERLHQKYGPVVRINPWEVHVKDADKYNTLYSGPTRKRNKDAWFSFVGWPQAIVSTEQHALHRTRRSVLRQFFSDQAILS

SEPLIRANIQALCRHFRSAQSRHYSLELHTAFLCFTSDTISQYAFGKRIGFHSLDQPELSTASKTKLNSTFELVQTTRHF

PWLCKLAHVFPWPAKLLNADFVGAYLQEKEVQDMVRKTITERDTGSSEEHRAIYPAILDDEKVPEDEKKFTRLTDDAIFL

LLAGTDAPGRALVMNLYYILQHPEVYERVRAELCASWTDASTEPRLTTLKQLPYFTAVLKEGLRLSALVTTRLPRAAPDE

ILQFHGWEIPRETPVSMTTYFILRDPEIFPEPSRFIPERWLLEPEDLRKLERYLVPFSKGTMGCLGPNMAWAWLYLVLGT

LLRKFEMKLHDTTERNVEMVRDKFLGQTERGMNRVQIKVLREYA*

 

>CYP5098B1 Aspergillus niger

gw1.3.1436.1|Aspni1

51% to CYP5098A1

RRQAAKLPPSPLPSLPIIGSLHQLGKAWLRQSRDWHRNYGPLITLKLGGQTIVLVGSQEAASELLGKRGRLYSSRPHFVM

ALDLMSKGDHTVFLPYGPKWKLHNRLQMSILGVRASRQYHSLQELETQQTLLDFVEGDNYELIFQRFQASLIHTMAYGRR

LPKQNDQRLHEVEALSKAFINAATAGNYLVNIFPILKHTPTCLAPWKKYAQQIHDRTISLNRGHILEAEKTMAWNWVKHI

RSLKESESLTDHELTFVIGSIYQAGVDTMTNLLRLFLMASVLNPVAVRRAQAELDKVVGNRLPSFDDMERLPFINAYVKE

VIRWRPVAGLGAPHCVIQDDVYHGFTIPKGTTILANQFAMELDPELWEEPEEFMPERWLQRPDQELDIFGYGRRKCTGQY

QAMDSAYIVMSRMLWAFQFNHRYEHGRKVELGPWDLKQDGNLYVAKPFRADIKPR

 

>CYP5100A2 Aspergillus niger

fgenesh1_pg.C_scaffold_9000313|Aspni1

61% to CYP5100A1

MNTAIIPGAAAALALIFFILRALSARSRVLNKKPAAAPLTVPYTIPFLRSTFSFVFDGPNFFIRASRFCQGRWPLRVGLL

GDEVYLVQGHKNISSIFSNPKLTVTRAYGVVLKYCCGMDQKAVDVYVSDTSGSRERPIPGSRIPSNRRVGYHTHENLFHG

LLGRGLGHTTERFDAAIKSSLDNAVPTGPTWTYVDDLTEFFEDHLGAAILETLFGPLLLTESPGFHRTLWKYDRYIMSMA

KRLPSWMIPEGYRLRDKVLSGIMKWHKRATELSAKHSADVGEDDPYWGSAMMRERHKMLLGIDEQDLRSVASTDLALIWA

DSSLVAELRSSLQDSIQPESGSLHYNMDKISKKPLLLSLYAETLRYGVQIHIPRCSPQQPLEIGKGVIQPDKLILINTAL

AHTDEEVWNTRDGQYPLDTFWGRRFLVDPLDPQSGPLKPSSAAYEFMKEQMRDKNSSTTGEQFTVQGLEGIWIPYGGGQN

ACPGRLLAKRIMLLTTAMMVTMFDVELLEPIPHFDSRRFGFGVRKPVTKVPFRIRRRC*

 

>CYP5104A3 Aspergillus niger

e_gw1.9.635.1|Aspni1

58% to CYP5104A2P

MQLLSLLVNPFTAGILLLLSTGGYVIYQCFLCPLARFPGPFLAKLTNWHRAYLTYEGRSHHRYLAFHRKYGAVVRTGPNV

LSVADPTAFREIYKAGGKFAKSASYSVPKESQAFDLFRQRNEKIHGEQRKLVARAYSMDSMVHLEPNVSSILTSMVQKLD

TLSGVVDLGAFLQLFAFDVIGAVSFSRPFGYVIAGDDNGVFSRLKQSLRSMSWLMSVPWFYDIHQKLKPFIGNWLAVNDR

NGYFYQFATQEIVSRKDRGGDDRDIINQLFAIQKTKPHFSDTDMAFMMTANVFAGSDTTATSLNAIFYLLLKNPTVYQRL

MQELEEKKSKGELSDLVTFQQAESCPYLQAVMYEALRLYPAAGLQLNRDVPEGGMKIGNYYVPEGVMVGSSAWVIHRLPE

IWGPDFEEFRPERWLEGDATAHTVSERFYFSFGDGSRTCVGRSKYFFFFFFFLTNCLLVVTMLTSCQT*

 

>CYP5104B1 Aspergillus niger

e_gw1.3.2127.1|Aspni1

47% to CYP5104A2P missing C-term

MGIISDLTRPDSTHHEPITYLLAYIACLSLLSVIPYVLYIRYYSSLAKVPGPFWASLSRWWLVLFSDKGNMHRLYPRLHE

EYGKLVRVGPNEVSVADLNAIQLIYGAGNKFAKSDWYSVWQGRRKFDLFAERNETIHGAQRRLVNNIYSMSSLKDFEHGV

DAVVERLMQCMQRQGSDATVDLGKWVQLFAFDVIGEITFSKSFGFLENGTDGGAFRQIENALRSASWVGQVPWVYWLHDY

MTPIIGSRLGIAARHGTIRQIAAREIMARREGKHVEEAKEEQDILSKLFDVQKKKENQLSDDDVLSMATSNVFAGSDTTA

ISIRSIFYHLLKNPTCLKKLRDEIEDRKRQGRFSDPVTLDQANDMPYLQACMWEGLRLHPAVGMSLPRVVPKGGIMIDGC

FLPEGTTVGVNAWVVHRDASIFGDDVEAFRPERWLGEKTGDM (1)

RRYFFAFGGGSRLCIGK (1)

NISWMEMSK (0)

MIPTLLNRFDIQLANPDEPWQETCW (2)

WFVKQEGLLVKLSPRKS*

 

>CYP5105A3 Aspergillus niger

fgenesh1_pg.C_scaffold_8000274|Aspni1

66% to CYP5105A1

MSLLWNVGVAALLAVLWTASEAVRRLYFHPLAHIPGPRLAALTWWYEFYFDVIRPGQYVFKIQELHTRYGPIIRITPDEV

HVNDVGFLDTIYAPSMIRRDKYGYQLRSLRVPGGLGTTTDHDLHKVRRESLTPFFSKKNIQYMEGLITDKVDQLKQLIST

HVARDTPVNLSDVFFAFSNDVVNNFLFAHRTDVLASEPKAATLRQNSKELLMGININKHFPQIPDFLESLPMSISRPVMP

PGLIDLLALFDVRLCAEQMNQRVREEIFMIKKDKESSVAHKKNIGPTGKASVFDSLVDNPNLPASEKTLLRLQQEGALLV

LAGTESPAQTLNIIFYHLLANPALLEKLRRELRAVPVPSSWTQLEQLPYLSAVIEEGNRLSFGVTARSARIAYEPLTYTP

SAYVSSTCPPSTRSKSYIIPASTPVCTTTLSAHTADTVFPDPFVFDPERWLGDAGKERRRFQMAFNKGGRRCLGIELARA

ELYHVVAALVREFDMALFETDADDVAFMYDYQVAMPKMGSKGVRIMAKLAH*

 

>CYP5108A2 Aspergillus niger

fgenesh1_pg.C_scaffold_10000032|Aspni1

57% to CYP5108A1

MASMIEAIQARLADDEHLLAQPMIVAGALFFLLVVFQLRRAGGSKAFPSPRLGYPLVGDALAFLNRPVAFVQDATRKCGP

IFHVKILFANIVYLRGTQLNRMYVDVKEDIWSFGGGIGIFLKKIAIPGYFDHFRNLVGSLNRGINRKVTLDRYTELAGEE

ADKALLKWSQQSDVKVFEEASKYVHRVIVRTLMGQDFYDEHIDELYDLLHRMEDEIGHPLNLLLPDWFPHPPARRLGKAR

DRFAEIFAQQMAIRRQNPEKWKGSLDYITYTLEDPRTAHLQEYYPSHHTVLMFAAHTSTVASIAWTAMELIRNPEYVEAI

RQSFQTNEDVHQSPVLLACVKESGRHYSGVHMWRTTHRPVQLEDGYTVPENWVVCTSPYLTHHDPEIYEQPQQWLPERWL

RPTARLQNLNNATDAAFLQFGAGSHRCPGENMAGIIARELVSRLVKNYDFQWGSQGPAKIDVSNMDFSKVGSPWLQGDAL

IRIQPRKSAAM*

 

>CYP5108A3 Aspergillus niger

fgenesh1_pg.C_scaffold_4000032|Aspni1

54% to CYP5108A1

MWRIPVIVA

LVAGLLYWVRKQGSQPSRKIPQPRIGLPVVGDAHAFGKSPISYIRQATARCGPV

FQINLLLTKIVMLRGAQLNRFYVDTREEVWSFGDGM (0)

GLFLEKVVVPGYLSHLKE

MVSSLNRGVNRSIALEHYTRIAGEEARKIATNWAEKPDIEVFEQMSRYTHRVIVRCLMGQDFYDHHLDELLDLLHRMEAD

IGHPFHFLLPNWVPHGPARRLHHARDRMAAIFNERLQAREQNPEKWQDSLDYIAYTLKDSRTAHLRQYFAAHHTLLMFAA

HTSTVASIAWTVLELLRNPTHLEALKTALATDADIHRSPTLIATLKETSRRYSGVNMIRWARQPHQLPADAAPGKGNIVV

PENCIVSISPYLTHHDPETYADPHIWDPTRWLEGGRLSETQKSNRSEVTYFPFG

AGCHRCPGEQMAGMIAREMVAHM

VKTYDVRWSSTGPPEDFEQLDFSRVGSAWLKGDARVTVKRDKQGEMEEA*

 

>CYP5110A3 Aspergillus niger

fgenesh1_pg.C_scaffold_22000006|Aspni1

71% to CYP5110A2

MAVHVPFSIHHVVDIGISTGPVVIVLVLLFGLAVVGSDSLDGWWQKRALRGIPIVDEGSYMRPKLRWKRFDAEKEYARAY

QQSAALSLRDAQFADMNMYCDVTDRTPIEAVHSCNNAESLNILNKLLARETDTALSQIFEQPTGKDWKELNTLQTILSLC

STVTMALLLGPDTAPDPVLHHHSTSFGEAIMSSCYRRTGYPRILRPFVWRFSSECRNLRKHLSLVRERLVPEVARRVAAA

RAADKTKDVRPSSLLDALIAAAFDNGSLSPDDQGRNDAAQVQLLADDLIFYHFELCKPTAFNIIFQLYAIMDHPEYKAPL

REEALQALKLTNGDWTVETLKHAPKLESFTKETFRLYDISGFVSFRRVMKPLTLNSIGLSLRPGTILLSPCRNVHLDPEI

YEDPTTFNGYRFYDSSREVCSPRVATTSLTFLTFSHGAGSCPARVLATQICRTIFIKFLLQYDVEPVQKEILPYGFTSGP

VYMPNPSVMMRIRPRSDGK*

 

>CYP5128A3 Aspergillus niger

estExt_GeneWisePlus.C_70180|Aspni1

69% to CYP5128A2

MAHIENLQGLIAQSLLLAAFAIVSAIFCRCFYRIYLHPLSSVPGPKLAACTSLWLAYHTYIGDECTVVCDLHRKYGAVLR

VAPNDVDIADKDALEPIYIARGGFPKTPAYSKFDIDGHTTIFSSLTLPERATRAKAVAPLFSTASIRSSQEALREVFDDF

AKRLQAEARTGRPVNVLNVTRAMAIDAVTTYLFHERYGAITEKTESMSASPFVDSFAGVGAFFNIVPGKIGDFVMEVIER

WSTTKNVEQSHGLIDQYNRRLIQTAIPKSGSYQSRLLEKSTIAQSQIELKDVCFAGTDSTGMNTATILWYLAKHPEIYDR

 

>CYP5156C1 Aspergillus niger

fgenesh1_pg.C_scaffold_15000299|Aspni1

34% to CYP4F11 aa 375-490 52% to 5156A2 frameshift after TTNY

M P  L  A  S  T  V  I  Y  V  A  I  I  T  S  I  V  V  V  L  F  H  R  V

F  K  P  Q  N  N  K  K  P

ATRSQNTLPPELRWSVAQLAHSFFTAQFDFIKEGFRVTGSKAFRFQLRKNQVIVVSGDEA

RRTFFGAKSLNLYEGFQVLIGT (0)

I  P  T  G  L  N  P  R  V  L  H  G  I  Y  K  R  L  N  N  L  Q

R  P  D  N  L  Q  N  (1)  

S  Y  I  A  P  V  L  P  Q  L  I  T  D  C  H  Q  K  M  N  S 

W  D  N  L  I  I  D  P  C  S  S  L  H  D  (0)

VTFQMIIRAVTSYEVAEDTRLVSRLKYFYDIIDASVKPLHLWAWVPGLATFYKLRASMYVY

WTFHQAVKRRVHSGVRRDDSLQQLLDSGESFQCIVG

FMMGLPIAGARSTGT

SGTWLLLYLASEPSWSRAVHNEIKDLTTNY

XXXXXXXXXXXXXXXX

AIPLAAWESQTPQLDLCIRETLRRAQPHTAVRRNIGPDLPIGAYTIPSNAFVLYPFSDAALNPTLY

PDPLRWDPGRTVVDNNAFIGWGGGTHLCKGQRLANLTLKIIVAYTLMSYKIDFVSKNGDVVTGVPVPDWNDYLTCRPQGD

CTLRFTKCRE*

 

>CYP5167A1 Aspergillus niger

fgenesh1_pg.C_scaffold_3000005|Aspni1

38% to CYP5068B1

MTLSALIFVLCMGIATWLLVSYYGKRQRLPPGPAKIPILGNIHQMSQGNRFKLYEQFHERHGPIISLQIGMADMIVLGSH

RVAQRLLGDKGARYSSRPRAVMADDLATKGMNMVLMPYGAKWQTHNRATVSLLNSRAVGCYEPVFDLQSRQLMCELLATN

DFSPRLRRYIDALVLTLAYGKWVREEDEIRLEVDRIIDVATETLTVGISWIDQFPALLYLPRLVSPWKKTGDHIHRITQK

VFDQLWKAGLESPSWNWSKKLHQACSSSSGTQSAGLYLAPEEQSYLMGVLLEGGTETSTTTLRNFFLAILIRPECAVRAQ

QELDAVVGSARMPELGDMEKLPYLNAMILEVLRWSPPTYTAQPHAGSEDGEIDGYYIPSQTPLLMNFRAMTLDKEYYSDP

RKFLPERWPQQGKNNATKLPLPVFGYGRRACAGRLFALRGIYFAVSRLLWAFNVKPAPHLTADGLQFLVDNYVDHGATQE

PPPFEVVIEPRSSQRRQHLEQAWKNTEAMDLDEILDEIGSKVDKL*

 

>CYP5168A1 Aspergillus niger

gw1.13.785.1|Aspni1

36% to CYP670A1, 38% to gw1.4.1072.1, AM270073.1, REVISED 2/10/2009

MIHLVSFLYLIVNVPTSWQIISGYLL

YLVGLFSSILSYRLFFHRLNGFPGPRWASVSKIWHLWKTRRSQNHFFMAKLHAQYGDFVRTGPSEITVFHPDVFMAVDGP

RSKCMKGEWYDLLHPDRSLVNARTSDIHRPRRRVWMQGFTSKALVGKEEQTLGLIEQMDQCIQDDMAAGRSSNVTDMIYW

LSFDRMAQFVLGKKFNMLTNPDWRFAIRTVQKALSILGPLSPAPWLVQIVLRLLPRVWILKDWFRTMAMTKGELRNVPTD

MSKATSLGAFLMESSQKDSTQDQWLGGDSLLAFVAGSDPTAGILHGLFYELARHPEQADLIYRELQQLQPEELSDVNAVR

RCKHLEAAIFESLRLYPSLPTGGNRKTPANEGITVAGVYIPPDTTVVAPRFCISRREDCYVKPNEFIPERWTTRPELVLN

RSAFVPFGTAFRSCLGRGLAMNDMMLIGAHMIQHYRMSFPAGDTGDRVFNDWKDQFTSCLGRLELRFERRTA* 41791

 

>CYP5169A1 Aspergillus niger

e_gw1.18.102.1|Aspni1

37% to 630B11

MYKEIIVLVYILIVLRVVLAPIYTYLRDPKGLKRFPGVSVAPITDLWGVLQQYLRTRTLAVHKAHRKYGSIVRVGPTNIS

FSTPEAIRDIYGHGTPALKDDFYQTFNSTHLNVSDAQDRDVHSIKRKRFAIAFSQKRIVELEPVVQDHLQRVFHILDSAN

GKEVDMKQIMMHLMYNLIFIHHLLSSTLHISTSLGWAPRIRSLLKHLTCCHSGWKHGTQLQHITTHFVRERVNMDIERRP

LCLELGELVTEAQNLFSAAGGNTEIALTSIIWYLAGNPHIVRRLRAELADAILPQTDPSALISYDLVKNLPYLRACIDEG

LRLRPSIRGGLPRVVPKGGMMVSGEWLDEGITVSVSTYTVHRDPDIFGADPERYIPERWLQPDARDMQRGFLAFSQGGRG

CLGRNIAYFQMQLVIAALVWRYDFALREEGWELEVMETFSAHTVSLPVVATRRE*

 

>CYP5170A1v1 Aspergillus niger

estExt_GeneWisePlus.C_30253|Aspni1 revised

40% to CYP5102A1 aa 98-492

MGVGAVAVLLLAVLTVLRALRNYSRLCAIPGPSVAGWSDFWRICVRNKSHYGRRLSSLHRIYGTVVRLGPRFLSVADGTII

GHLDHGVDGG (0)

SPELQHRNTVPLNSVTISSDTLQTTHPTWERSQGIPE

YEGVIDPSTKQLIKAIRRYRVLDITSSLRIFAMTFINQLTADGLLQEKHNNSTGSGSRWLGVFSTVEYMLIRS

PVTALKRDRGRRLATCATLPVAATTVSVGENGAGSSTGTSPSQQRPCDGSRMKPSPNALRGAHGAAATFISLFYFLLRHQ

DYLDRLRFEIDTSFGIGSLSDIPRWRELNRLSYLDAVLKETMRLSVDFEEEIKAAVDGVTVAGFSVRKNTTLTWNSHVLH

FDSETFGNDVHSFRPERWLMADTQQRSRMEQGLISFNRCVRDHPEAQVVWMELKKVVVLILMKFNVSCTREILPAHH*

 

>CYP5170A1v2 Aspergillus niger CBS 513.88

XM_001390853.1|

93% to estExt_GeneWisePlus.C_30253 (allele)

MGVGAVAVLLLAVLTVLRALRNYSRLRAIPGPSVAGWSDFWRIC                   VRNKSHYGRRLSSLHRIYGTVVRLGPRFLSVADGTIIGHLDHGVDGGSPELQHRNTIP                    LNSVTISSDTLQTTHPTWERSQGIPEYEGVIDPSTKQLIKAIRRYRVLDITSSLRIFA                   TTFINQLTADGLLQERHNNWKGSGSRWLSVFSTVEYMLIRSPVTALKRDRGRRLATCA                   TLPVAAPTVSVGENGAGSSTGTLPSQQRQCDGSRTRPSPNAVRGAHGAAATFVSLFYF                    LLRHQDSLDRLRFEIDTSFGIGSLSDIPRWRELNRLSYLDAVLKETMRLSVDFEEEIK                    AAVDGVTVAEFSVRKNTILTWNSHVLHFDNETFGNDVHSFRPERWLMADAQQRSRMEQ                 GLISFNRCVRDHPEAQVVWMELKKVVVLILMKFNTQLLHAAEPSIDAEDNFTPPSLMV

GFTPRVPGF

 

>CYP5171A1 Aspergillus niger

fgenesh1_pg.C_scaffold_4000449|Aspni1

37% to CYP590A1

MAEISLRTALTILVGIYLLYKLLSFVRFYIIGRRSGYPLVVTPLFTQHTLWQIVGPTFQVQLKRYLPTWLHEHVDIHIHG

WEFRHKNAMHRRYGKVFAIVSPDECSLWIADPTVGATVLQRRKDFIQPDVVAKFMGVFGPTLIQSNGEDWTRQRRIIAPQ

LNETIMGEVWEESCRQARAMLEHLLQHPGG

X

DTLTGLRSIAINVLGQAGYGQNQTWSPDFVEALGEDWQGPRVSYFKTIAM

VTDRFVEAVLIPNSLKMLPCMPQSLRQLGRQMGKVPEYIKEILNEERNTKSS

EVSKTRHNLLDMLVRFADRGEEDS

XXXXXXXXXX

SKLS

LSEAEISGNLWVFTAAGF

DTTANTMGYAVMFLAQYPQWQDWMREELSQLDANTSSWGYETFSQCPRVLAVMFETLRLFTP

VLHSTRCVAATQQIADSDGTHVLTPPMNVFVSQQSIHRDPNIWGSDVDEFRPTRWLDDAGQVVTPAKGTFIPWSAGPRIC

PGMKMSEVEFVGAMATLFRHARCEPMQKGKLLQQMDDSISKLTLQVRELREVQLRWVPA*

 

>CYP5172A1 Aspergillus niger

e_gw1.9.995.1|Aspni1

37% to CYP5112A1

MTTWGIYSLALLIYRLWLSPLSRFPGSSLARVTYWYEFYYDWFRPGQYFRRINEMHQRYGPIIQVTPDELHISDPSYYKH

LFVTGGSRKTDMYPGTFRGTPFEGYIQIIKTHNVHRFLRGPIERYFSRRSMIAAEPRVKSCIKRFNSRMEEFEDTGRPVN

MNYALLSLTVDLVSATVCEKPTKYLSDPDFNAAWFRTRMKGIMAVPLLAMLPEPLRYGTASLFMWFVQFISSHTLVKKEY

ADCKYEQSFKDALQPSPTVNFDNTERTDAPKQQFGDDIYDLGGQLIQEGGIYPMSNCLQTIIINMALDSKKLHNLQNEIK

TFLIENPETEVTWKEIEKLPYLDACLKEGLRLVGGGMRRTTREFPDTDLHVEGWTVPRGTPVGMSSYWMHMNPETFPEPE

KFRPERWLQSEKNQDPLQHEYFVPYSKGSRDCLGKYLAHMGLCHIMFELYRPGALRLELYDTDEEIMKMGRGYLFSLPEM

ESEGVRVLV

 

>CYP5173A1 Aspergillus niger

e_gw1.6.1215.1|Aspni1

38% to CYP526A2

MAPSYIASFVELFHGYPAVFSITICLVGLYVLYRWLLPSPLPGIPYNKQAATSILGDVPALRGDPAGLAKWCSKQLEEHG

SPICQALMGPLSKPVVLVADVGQTRELLMGRSDFDRSSYIIDRFPLFGEFHLNMKTGDSWRTSRSWLKDLLAPHYLHQTV

GPIIHSSVLNLIHLWESKARVANGRPFSMLADLKTLALDVIVRFHFGQDFQDSALRRQIEFVEQLDNSQLGVGKHTDVIF

PQASLHPFQQGLTDVGDRMAAIYTTKWPPSIVSWWARYMSPYYRKFFVGKDRFIRKHINLALQRFGNDEEAKTGIDYMVY

REQKASRKADRQPMYGKQIMIDEAYGNLIAGQHTTSAALVWILKLLAEHPAVQTRLRDELQTVCAAAVQEGRLPTAAEII

QFRLPYLDAVLEETLRLRAAMLVPRDATRDTELLGRRIPKGTVVLLVCQGPDYSSSPSSLYWSDVKTTRKYPGGGNPDLE

AFDPERWLVQNERGELEFDGSSYPQLAFGLGIRACWGRRLAQLEMRIMTVMMTWKFDFLDVPEALAGHEATYDISYRAKK

GYLRLRSR*

 

>CYP5174A1 Aspergillus niger

fgenesh1_pg.C_scaffold_5000290|Aspni1

34% to CYP578C1

MLAVVVGFTFLVSWIVASIHRNRNSSLKDIPNAHFSAPYSRLWLLSLRWRNLENRTRIQLHRRLGPVIRIGPRDVSVNCI

DDGVRTIYSSKFDKDESFYHELFDQVGYMVTMTGNDEHRERKRMLSRPYSNSYILNSQTLGSVLSRVSSHLREKMEEWAS

TSTSVNVYQQAKCCTLDVASGWLFGSENATDTLRDPGFENDLTTLAAAASKIVSVRTTLYWPFTYFASLVGNRLPNPDAT

GRWQAWLTRAITDAYRRHPTKPSSTASLYDSFYDAFKAANPKMPRNEMASFIAVECDDHLSASHLGLGTLLAYTMYELSR

HPDYQRALRKELLSLAEPSDQSLAHRLAALPVLDAIVTETMRTRAPCPGPFPRVVPDSGCRLAGKFDVPGGTIVSSSAWA

LHFNPVPFPSPEEWRPGRWLEADESTVAEMRKWVWTFGSGARVCIGTHFSMRVIGELLATVYTDYETYLDDEFRGNVEQV

DAFSAGPIAGCLKLKFRRYT*

 

>CYP5175A5 Aspergillus niger

fgenesh1_pg.C_scaffold_2000360|Aspni1

34% to CYP54B1 aa 171-515, 44% to gw1.4.1134.1

MYEEMEYALDRELGNPHEWHPLPTFPTILRIIALVSGRINIGLPLSRDPTWLTLYTKYPLTMMESVSLMKYPSILRPLAQ

HFTPSLRELDSIRDEITALLTSEYEAILSEKSDRNTMVRWLWENCEEHERTITYQSQVQAMMSIGTVLANAAAAAQCLED

LAEHEEMIPLLRGEFEGVVGGDGKDEISKQALTSLSMMDSFMKESQRFKPPGAGSLFFIGLTNNVGTIVTFERKVLEPFT

LPDGTRLHAGEHIAAPAFHVGWDPEYIENPEVFDGLRFHRLRNQGGLSATTAAGKYHYVSVNETSLHFGYGRNACPGRWF

TAIQIKLLLGRLLVRYDVTSGEGSDTVLIRRRKGGEDGV*

 

>CYP5175B1 Aspergillus niger

gw1.4.1134.1|Aspni1

36% to CYP54C1 aa 275-516, 44% to fgenesh1_pg.C_scaffold_2000360

SNKPNTMLQWVWDDSTEKDRTDEHQSMIQILATVPSTYTVAFAATQALFDLAARPEYIPIIREEFESVCDSCEEKRLTKE

AFGKMTKLDSFLKESQRITPLALISFERKTLENIDLADGTHIPKGSHIAAPSYHIGLDESHFSSPETFDGLRFHNLQQAE

FERTGKPSTKHQYVTVNESSLHFGYGLQACPGRWFAAIVLKLLLGLMVTEFDVKLMDKGEGRPKSEIDRFFIYPDSTKMV

VLRKREDV

 

>CYP5176A1 Aspergillus niger

e_gw1.4.1066.1|Aspni1

32% to 671A1

MALFFDLLDIAKEKGPLLAAAGISAHVFYWSRGERSAKEGRAWVYANLIVNTLALLTTINNHGSWTSIYAWVLGISTVFV

LNICFYFSLFTSVLTYRAFFHRLHHFPGPFSLKLSKFVTGYENLEKNRNFERVWNLHKQYGDIVRTGPQELSILSAEAID

VIYGPSSKCTRGPWYDRLKGSGDFTHDYAVFHMRDPAVHSQRRKALWDKVFSGRALKSYQPMVIRTTEQFLDAVAQRVNQ

PLSVPSTMSLLSYDLMGVVGWGHSFNNIETWELNPSLHFIKNMRAGQHVMVHTPWLISLLMSLPGAGSAIREYGNWIQDR

IQEKRQQEERNEVPGEDIMTRMLPSMRGLSKKALYSEGELLVIAGGDTSSVTMSVIIYHLASNPSLQRKLQAELDSAAAK

RQKDPAPPTESPEDTYYRSISSLPYLNGCVSEALRIQPPVHGGIQRKTPPEGIHIPNEKGTSTFIPGHTLVSVPILPVQN

DPRYYRNPEEYVPERWTDEKPDWIMNRAAYFPFVGGAYSCVGKGLAYIELRVVVAMLFGRFNVRLAEGEDGRRFREETRD

TFVASLGEFRVVFSERAE*

 

>CYP5177A1 Aspergillus niger

fgenesh1_pg.C_scaffold_6000319|Aspni1

35% to CYP5116A1

MTITTLMKFILAKYPYSKLCHCPYPKMFSGILKGIALLILILFVRFKYTHSFLHKTTIFKTPKQCHMIIAADGQFFDKRN

LLSPYEARTFSNSRFKSAFCIQNAFTSSDQDFVNEHVKNIKVLINLTPLEWNHLSQSLQQTARYWVNSSEGTVHLAVITQ

TLSLRLVLVGVCKLDSRISVSEDPYFADFARCINKSWILAKGPDILPFEDNEELQDYIGIFFPSCGPIQPEENPLNVILP

GYETSWRVALRMFLEIRRAENQVWVDKMVSFALHPTKVQFQDNSDGISAEALLSEALRLYPPTRRIRRTFRFENGRNGAV

DEDTFAADIEACHLDKSIWGTDALEYKPSRFATLTDEQKEAYMPFGSSPFLCPAKPVFGPRMIGMVVGILFFALQEVGSW

RLVGRDTHSANGYVSGERLNNDRGAFDDLLLYLNTK*

 

>CYP5178A1 Aspergillus niger

e_gw1.16.101.1|Aspni1

31% to CYP680A1

MALFSVLSNALSELPVSIWLAAAATFAVYHAIRAVYLIFFSPLAIFPGSPWAALGEYWEAYWNIGVRPGHKGQTLFKLEQ

MHKRLGPALRMGPNEVHIYDPAFYHELYRPGSRYYKDPSMHKVLGAPTSTLAESDPVRHKQRKAPLEPLFSKKNILSLEN

MLMEHVDHCCQRFDELYSQGKPVSMEWALKSLAMDMVSQFAFGQSLNAIADPEFKSLPVRVFQQYLPSLHVIKAFPFVRL

LSSLPLWIARRISHSVEMGHELEQFAARRIDEYIEAAAQGKTPNFPTVMERLLIPIPEKGYEVPDKQGLRDEILTLISAG

DDTTGIANTVTLFNIIHNRTIHDRLLAELKTVMPTPTSHAQYIQLEQLPYLTAVIKEGLRYSSPAASRTPRLVPPGGVRL

PDGRFIPAGTRVGMAIYHIHYNEGLFENPHEFDPERWLQGPEITAKRAKFLVPFSRGSRSCLGINLAYMEMYMAIAYIVR

RFDLELVGTTPEDMKWDDMVVPQFHGEFRALTKRRVD*

 

>CYP5179A1 Aspergillus niger

gw1.5.246.1|Aspni1

29% to CYP547C2

boundary between first and second exon not clear

MRYLGIFPRDPLLLIGAVIVSWSTSFPLTVCATTLLKRQRSTFNDLPGPQ VRANTASLIFSPADANRC &

SVNWLYDRVFDVFDEPLAKNVTAWVNERAYPGGLMHFFGLFGSEY

IVPTDHEGLVEVLSTRSYDFEKSRAFRRYSVRFFGDSLVTQEQEVH

NRNRKTFMPVFNQTNINAVRPPLTSKSRQFNDYISSLLKMSGESQRSSEGRGTAVVPVTDVVFRATMDTGSILALGIDLE

TIKGRNTHILQAFKTLFASNRQKKIRFILHNLLPGWLDQLVPSTEAKDMDRARILLVESVVNMMQGKLAKNERTGDHLTY

LSNLEQSGPFNHDEYIGQLRTIIAAGFESSGGSLSFVIYCLAANRDAQQSVREELRNAKRGRMELDXDEYERLPVLNAVV

MESLRLFPSFGLLLRRAIRDTTIKGRLIPRGTHIGICPKAINCSRELWGDDAEEFNFERWIDRSDPHNPTQVPTGGAPST

ACMLSFGYGTRSCVGRHLAMAQIKRQIALITERFYVETEDDKVPHPSGLFASTPPLDFRLRFTEVE

 

>CYP5180A1 Aspergillus niger

fgenesh1_pg.C_scaffold_9000194|Aspni1

28% to CYP5125A1

MTEALCSWLLAVACVLLIANALYYSLFQNISISSIRVVVRDFRDHRYYRPWAPKPIMIPARKRIMTELSETSVLSQRAVY

SDLFGFKHTLNGVDHNEINTRKSRLLSRVLQVRGPTEFEKLYPYLLRNLKAILDAELSSASDSLLRNALLNHPRQIKACS

AAFQLTPRFLAPLVHAIITWRGSAMHLIQDRLINTITAGIDDLDEKPEIKKLTLLYHMVDLSAADRSYWTPERLSQSILG

LWLAASHQPWVNLHAILVELCLRPEWQDLLRDEALQNQRNLARNMNELPLLDSFMRETARVNSLDRVAIRRKALKDYSFS

SAPLSIAAGSILCVSSYDVARNEHIYPDPEQFDGGRFLTGRCKDTSRKFTDVSENHLIWGYGSLAWFAQFFPGRHHAAFM

IKMVVVHIVTNFTLQLADPEAPRWWTWEDFRMPYASTRVLFSKRTTKTDAIS*

 

>CYP5181A1 Aspergillus niger

estExt_fgenesh1_pg.C_100184|Aspni1

31% to CYP534C1

MDVFIWRLFLGSATVLAGFTSWSLVCLILNVREARSTGLPYVILPCSLLGAPWLLSQPVVLPLLKALPRTWTSKWLPLLI

FNDGWHLGYTPFEQVGADTFLAVSPGGFVLYTCDRHVSTQLFQDGRFGKPAHLMQVLNIYGPTITGTDGPESRLYRRITA

PFFREDTLRQVFTHAIEGAQVLGLALNQPAAYHQLRTLAARLSLNLLTRILRLTTMWSTVVMALLIKAVSAWSPLKSHRQ

AIRAYDDLGQYMHELKTTTESRLQDKEYLLNQKGTASLGDLIVQAGISTDSSTSPILQPHQVMGNVFLFMFAGHEANANT

LTFVILLLACHPTIQTAVQSDLDKILENTPPSHWSYDTHYEPLMRSLVGAVIKEALRLFTVLPVLPKYVPPSGPAIPIVV

SGQSHPLPPGTVAFVNTSATHRHPHYWPTVNDKSAKSTNQEDPTLRPYPTTDFNPYRWLETQPSGSAPDNETRLRSSTGF

TPAPGTFVPFSEGSRKCLGHKFALVELCAVVALLFHQNSVSLLTDPADPSDTWAAARIRADRALSEGVKFNMSLRITQDV

PIRFATRKTKAT*

 

>CYP5182A1 Aspergillus niger

fgenesh1_pg.C_scaffold_11000427|Aspni1

33% to CYP609A1

MFGAACYALTQCLYLIAVLLLVQCLRLLWKHPFPANAPKLVSGYPLLGALQFFSDRNGFCRISKAASPSGNYSYYLGRHR

MVGLCGPQGRKVFFESQDLDVDEGVAVLLPFVNLVEASNDPSSDTHTAYLRSTLRTRLLRTQSLEFVPHTIGTYITATLN

HIEAEGLIDPFPEMNLYYTQSTMAVLGVEKVARSPELSRKIGELLGLLEGTFSATDIVIPWLLNPSHLRTVIGVARLYVM

LWQIIGNQKMEQQQQPLSHKQESENVGILQDLITKGRSMRAMLQANSPTVTSWMLIMLATNTHWMARVRQELNQVVSKHR

KDGESADQVLQGLGVSTWEHEFPLLHACLLETVRLVLGLVTIRKNISPNDIPIGDKGEVIPSGAYATYDLQEVFQDPAIY

PDPQRWDPGRFLSDRAEHMKEYLAFCGFGAGRRKCRECASYIYHDSIF*

 

>CYP5183A1 Aspergillus niger

e_gw1.7.1018.1|Aspni1

34% to CYP660A1

MVLDCTQDSREPPAVDLSIPFISPFFRMCWTGFDYYRKNRRFPIYTIRLPGLRLYVVNSTSLISAVQHHPRTLSFSPILA

RVAGTLIGATKPGCKVLGDDDENGFIRRFHDFNQSALSAGPGLEAIRTRFWELVTLSQSRQYTDSPGYPGMYEWISHEVM

MATSEAMYGVQNPFRDPGNRAAWQQYQIGTTRLTIGWLPSIIANQPLRAREALVQSFEQYYSKRGFEADQASSYMKDQYL

VFSRSGLSDSDIARTQAAFSIAILGNTIPAAFWLLYHIYSNEIILQDCRKELYAALQKRSQENDDHRPMLDLSSLEQSCP

ILASTFKETLRTHSMGTSVTQVVQDQVINNQYLLKKGSMVMIPAIIQHSDPSVWGDDVNEFNYRRFVRQNTNDRKRSHNP

VGFRVFGGGWTLCPGRHVAASVILGFAACTILNFDMKPRSGEWVMPTVEKSHLGAAIAPPDEDIDIEL

 

>CYP5184A1 Aspergillus niger

gw1.4.1747.1|Aspni1

32% to CYP640A1

GHTFSFLRNIEKTIDNAMPYLKTEDTPFRLHVGGRSLYVVQDVRLISEIHKQTKLIGNDHFLDILMAASGVLGPTRARLW

STITAKRQEPIPRAITENVRRGLRAQPQNNPLTLTILAQMDKTLTPLAASDSLRRSLAEPGKVSLFKWTVDAFTVTVSDG

AFGKVCLDMFPEVVDTMFLLQTNIYSIFTRRPRILAPKAYAASDKLACILAKYFALPTEKKLDCAEFVTMTEDEIRAAAV

TKEELAMMYVWVFWGMLDNPSTAAFWVLCRVLYNPELLATIREECEEAFVRNKPGAPSDIPARLECCPILKSTFEETMRL

HSGTHVFRHISEDTEIGPYRLRKGSNILIPYNRIQVSKTHW

 

>CYP5185A1 Aspergillus niger

gw1.1.1982.1|Aspni1

45% to CYP5083A1 aa 298-455

M  T  L  T  V  S  P  N  L  F  A Y  P  S  S  L  H  K  P  S  P  E  G  L  P  P  A  L  L  S

GPVVRIGPSELSFATHSAFDTIYGPYGDKNFSLYGS

RKGLLGSLGGMAESLGNSTDKEN

RRKLRPLVATSLNELLAAKGEEYCHLAMDEQLASHHVGQTEATPVSLSTLNNRYLW

QFASMAANGNRGDETDRGTSFTNIFMGLSFMALTQVIVSFDPHVDWLDRFMCFLETLFIF

FSIYGTADNMLNALFYFLLRNPQCLKRLEEEVSCVGATVNELSDDRLAKLPYLNACINET

FRIAPAFNGGILQRVSCGATVDGVYVPPGVA

VSVDHYTLGHDPQYWVKPDVFNPERWIDPDCKDNFKASRPFLIGARQCPGRQMAYQMFRVCVAKLVYLYTFEL

LNKDFDIERDTFSSYHWTGVKLDVTMKPRTPGVLGY*

 

>CYP6001A1 Aspergillus niger

Supercontig 17: 397517-401111 (+) strand

76% to CYP6001A1 Aspergillus oryzae

MSGANNHSIVNGIGSTISQVEKAISASLRPLPTATGNGTYITEPDQTGIVKDL

SHVDFTDIKALLEVVKDAVTGQPVDDRHYIMERVIQ (0)

LAAGLPSTSKNGKDLTNAFLKQLWNDLEHPPIS (2)

YLGRDSSYRKADGSGN (0)

NFLWPHIGAAGSHYARSVRPTTVQSPSLPDPS

TLFASLLERKEYKEHPNKISSVLFYLASVIIH (1)

DLFQTDRSDFTLNKTSSYLDLSPLYGNNQDEQDLVRTFK

DGKLKPDCFSSKRVLGFPPGVGVLLLMFNRFHNYVVENLATINEGGRFTKPDESDVDAST

KYDNDLFQTGRLVTCGLYINIILKDYVRTILNINRTDSLWSLDPRADIQDSLLGSAPAEA

TGNQVSAEFNLVYRWHACISQRDEKWTQDLYKDLFPGKDPNNVSLQEFIRGVAKWEASLP

EQPPDRPFAGLQRNADGAFDDGDLANMFADGVEDCAGAFGAGNIPSVFRNIEALGILQAR

SWNLATLNEFRKFFDLAPYKTFEEINPDPYIAAQLKNLYDEPDLVEMYPGVIVEATKDAI

VPGSGLCTNFTISRAILSDAVSLVRGDRFYTVDYTPKHLTNWAYNEIQPQDSVDQGQVFY

KLVLRAFPSHFKGDSVYAHFPLVIPSENKKILEKLSVAQDYSWGRPSYTPSPQFVSSNAA

CISVLNDQEAFKVTWGSKIEFLMRHNNHPYGRDFMLSGDKPPNAASRRMMGSALYRDKWE

SEVKRFYEDITIKLLRQHSYQLGGVNQVDIVRDVANYAQVHFCANVFSLPLKTESNPRGI

FAESELYEILALVFASIFYDADVGTSFQLNQTARDVTQQLGELTMANVDFVNKAGFIANL

VSSLHRHDVLSEYGEHMIQRLLHSNVPPAEIVWTHLLPTAGGMVANQAQLFSQCLDYYLS

DEGSIHLPDIKRLAKENTSEADALLLRY (2)

FMEGARLRSSVGLPRLVAKPTVVDDGGSKYTLKPGQSVLCNL (0)

VSASMDPRSFPEPEKVKLDRDMSLYAHFGFGPHQCLGMGICKLALTTMLRVVGRL

DNLRRAPGSQGQLKKIAGPGGISMYMTADQSSYWPFPSTMKIQWDGDLPSLATN*

 

>CYP6001C15 Aspergillus niger CBS 513.88

72% to CYP6001C12 Aspergillus oryzae

An02g07930

MLRRFSSTFKRSSKGDRDSKPNGTQ  

VNGQKRQSKVPAPRKSSSDESHSDHGVESDDGVSVFEKYAQVLHASRRPLPNQNG

DGTYLEQEHSGSLFKDLRALGFKDIGTLKDLIKTKAKGEYIDDKTMLMERIIQLVSSLPGNSKTRVDLTNAFLDELWGSL

PHPPLSYMGEEYAYRSADGSNNNPTLPWLGAAGTPYARSIAPLTIQPGGLPDAGLVFDCLFAREKFTPHPNKVSSLFFDW

ASLVIHDIFQTDYTNSHVNKTSAYLDLSILYGDDQEDQNLVRTFKDGKLKPDTFSEQRLQAFPPACSVLMVMLSRFHNWV

VEELAAINENGRFNKPDPRLDEEKARKAWEKYDNDLFQTGRLVTCGLFINITLYDYLRTIVNLNRSNSTWCLDPRVQMEG

TKSTPSGLGNQCSVEFNLAYRWHSAISANDEKWTEEIYEELMGKPASEVSMRELLVGLGKYEREIPKDPSKRTFAGLKRQ

EDGTFKDEDLVRILANAIEDVASSFGARNVPKVLRSVEILGIEQGRKWNVGSLNEFRKFFDLKPYETFEEINSDPDVADS

LRHLYEHPDYVELYPGIVAEEAKEPMIPGVGIAPTYTISRAVLSDAVALVRGDRYYTIDYNPRNLTNWGYNEVRYDLNIN

QGCVFYKLAMRAFPNYFKPDSIYAHYPMTIPSENRNIMKNLGRESHYSYDRPRYTEPVPNLLSYANAKLVLNNQKDFTVP

WGGLSSIHAGKGGADFWSKSFDNEQWRNSVKEFYEDATLKLLNEKSCKLAGNKQVDIARDVGNLVPVHFVSKVFSLPLKT

KSNPRGIFTEHEMFMIMAVVFNSTFFDVDPTKSFPLQHAARAVSQELGKVVEAHVKSINHPGFLHGIIDSFRDDHNALKD

YGDQLIKRLLESGLGVSDVTWGQILPAAVEMVHTQSQMFTQIIHFYLTEGQKYLPEINRLANENTAEANDRLTRFCLEAV

RLNGNLGIYREAQADINVSDETGQYSVKSGEKVFVGSSKANRDPQAFPSPDEVRLDRPLDSYLHYGLGPQSGLGKDATLA

AVTAMVRVVARLDTLRPAPGAQGQLKKIPQEAGFSVYMREDYGSYSPFPTTYKVHYNGDVPAPKRQVTTA*

 

>CYP6003B3 Aspergillus niger CBS 513.88

fusion with diooxygenase, P450 (C-term) part may act like a hydroperoxide isomerase

XM_001395183.1 (An12g01320)

MGSIFAALLLCLLSYLYLRVFADDLTRPFQILAKFFSSHQHPAW

KLRPRFLPKATRAALSSIAGTGEGLWQRLYARTFHAQELAEVEDDVKYQAGEPYGDPD

VLATGLVKDLSALGLKGKRNDLRTLIQLVKAKGKPIDDRQMLMEKVIAIVSMLPRTSK

SRQRLTGILIDQLWQSLEHPPLSYFGNKYQYRTPDGSYNNPLEPDLGKAGSPYARSVP

RLKALHGVQPDPGLLFDLLMARDDTTFRENPAGISSVLFYHASIIIHDVFCTNRRDPN

ISDTSSYLDLAPLYGSSYEDQLRVRTMQRGMLKPDTFHEKRLLGQPPGVNVILVMYNR

FHNYVADVLLKINENGRFTLPPTTSEDAKRKALAKQDEDLFQVTRLIVNGLYVNISLH

DYLRGLTNTHHSASDWTLDPRVAVSRAFDADGVPRGVGNQVSAEFNLLYRFHSVISRR

DEQWTNEFLKSLFPDLKKPLEQLTPQELMQGLINYERSIDKDPSKREFGGLKRNQDGR

FNDAELVQILKDSMEDPAGLFGARMVPKALRMVEIAGILTARKWNLASLNEMRDFFKL

KRHSSFEDINPDPNIADLLRKLYDHPDMVEMYPGIFLEDAKPAMDPGCGGCPPYTVGR

AVFSDAVTLVRSDRFLTLDYTASNLTNWGIREVQQDYDILGGSMFHKLIQRALPGWFP

YNSLHATQPMFTRKMNEQIAKEIGTIDRYSQEDPKPPPRTVMLANHATIIEVLKDQDT

FRVPWARYLNDMIPGKRFNDYMLGGDGPVNAAQKKLVKSILFSPDQFNQLLSQTTVRL

GKELLELNALQLSKDLNQVDIIRDVAIPLNARIMADLFCLDMKTPENESGSMNAATVY

KHLMNVRTWGFNNTDPGLMLQRRKWASESAEALVKTTLKVVNEQAQPQKTRMLGKLTG

YQQSEVSTLRWYGNNVVKQMMEMDMTAAGTAEVCWLTAVGGVGAPVGLIADVLQYYLR

PENIDHWKRIQNLVSQPDNSGSIDKLLRQYVLEAQRLTSMECTVRVCKAHRTINDQEF

KPGDVVITLLGPACRDPTSIPDAETFKLDRPSNAYIHFGYGAHECLGKEIGLTFAVSM

LRVLAGLKYLRPAPGDMGMLKSIIVDGRRVYLNDSWSWMTRDPTNGGIGMSTQYSFGQ

HHHHQYHEITRTSSSSLPSMLGDDESYGRFSGTLN