Kluyveromyces waltii P450s

 

D. Nelson

 

August 9, 2009

 

3 sequences

 

>CYP51F1  Kluyveromyces waltii

77% to CYP51F1 S. cerevisiae kwal_154-g13.1

MDSTNSSVVGKIFSKGIEIGSALLSRFLALSIAQQASLIIAAPFVYVIVWQFLYSMRKDRVPLAFYWIPWVGSAVTYGMR

PYEFFAECQEKYGDVFSFVLLGRVMTVCLGPKGHEFVLNAKLADVSAEAAYTHLTTPVFGKGVIYDCPNARLMEQKKFVK

GALSTESFRGYVPLIAEEVYQYFRNSKNFDMNHKKSGVANVMVTQPEMTIFTASRSLLGKEMRNLLNTDFAYLYSDLDKG

FQPINFVFSHLPLEHYRKRDHAQQTISSTYMKLIKQRRENNDIQDRDLIDTLMKNSTYKDGTKMTDQEIANLLIGVLMGG

QHTSAATSAWMLLHLAERPDLQEELYAEQMEVLDNGKKELTYELLQQMPLLNQTIKETLRMHHPLHSIFRRVERDLPVPK

TQYVVPRGHFVLVSPGYCHLQDEYFPKANTFDPHRWNNDYKSSYATGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHF

AYCQLGVLMSVYIRTVKWKFTPKMHGVPKPDFASMVTLPLCPAEIEWEKRDPQQAL

 

>CYP56A11 Kluyveromyces waltii

59% to CYP56A10 Saccharomyces kluyveri kwal_162-g20.1

similar insertion as in 56A10

MNSILWGLIGVIFFLILRIVVPPFNFPRNIPTIPFYVTFLATIWDLDQEDIFNLYLREPLEKYGAVKLYFGSRWNIVVSR

PEFLAQMFKDEDTFAKSGNHKKIPYGVIAAYTGENVISAHGAIWKTFRRAITPGLQLFDHTPLVKNADLFCSLISKRLTK

SGSSSIGGSTSSLDEKESWQFPTA

ASGTLLMSELIQRLSLANISEVALGLDIGTLTEESPELHLKLKNVKSHIFKSLYLN

FPLLDKLPIPSRQRARGYVEDFRRCLMKAVEMNLLNNYTFEQTSFSSSDLIRSYNREEISKKQLIDNIVIIMVAGHENPQ

LLLTTCFYMFGKNRKWQDLVREEVQGCGIENLNDLPLLNSFIFECIRMYPPLSQIINRCTTKKCVLGTDIVLPENVYLGY

NVYSTGRYKSAWGDNADCFIPERWGNNIEEITKEWRHRKNTCAMAAFHGGRRACLGEKLALMEVRIAMAAVLKNFEWTLA

ASWVDKVTPAGPLCPAGLEIEISELSKH

 

>CYP61A1 Kluyveromyces waltii

82% to CYP61A1 S. cerevisiae kwal_095-g1.1 C-term part only

MCALSLKAFCGDYITESQIRKVADDYYLVTAALELVNFPIILPFTKTWYGQRTADMTMKIFEKCAQMAKDHIAAGGKPKC

VMDAWCELMHNAKNKNDEDSRLFHREFTNREISEAVFTFLFASQDASSSLACWLFQIVADRPDVMQKIREEQLRVRNNDP

SKPLSLDLIDEMKYTYMVVKETLRYRPPVIMVPYVVKNKFPIAPNYTAPKGAMLIPTLYPALHDPEVYDDPEEFIPERWV

EGSPANEAKKNWLVFGSGSHVCLGQTYVMMTFTALIGKFAMYTNWEHKVTPL