55 590
513F1     -------MILSLLFLFVITLYFLIPSR-----ISKINKNIPGP-IGYPIVGNLFQINK---
513G1P    -------MIYFIIIVLIIFLIIKNL----NNRIYQINSKIPGPGFSLPILGNLHSMNN---
513E1     -------MNLYISILILIISLIIFFKN--NNRISKINSKIPGP-IRLPIFGNLLQINK---
513A1     -------MNYLVGLVLIFT-IFYFFLQ---KNDKNMNSKIPGP-KGIPILGNLLSMKG---
513A2P    -------MNFLIILINIIIVLTTIIFLK--KIIKKKNKYIPGP-IGLPILGNLLSLKG---
513A3     -------MTSLTLYLIIFSIILYLFVN----RNKRKNLKIPGP-NGIPIFGNLLSLSG---
513B1     -------MNLLVLSVILAIIIYLIFKRNYKYSPSKINSKIPGP-IGLPIFGNILSLDNK--
513C1     -------MNYLVLILVSLVSIYFLFIKN-QDRKKKINSKIPGP-KG-FLFGNLIELARTK-
513E2P    -----------------------------KNRINKINSKIPGP-IGLPIIGNLHQLKNNP-
513E3P    -------------------------------------------------------------
513D1     -------MGISSIIIILFIIVLLKKLIKKEDRIHRINKNIPGP-KSKLLVGNLFDLKG---
514A1     ----MNTIFTIILTITILVLSLILKDLLFEGRIKKINKLIPGP-STIPVFGNLLQINA---
514A2     ----MNLIYTIILTIIILVLIISIKDLFFEDKIKKINKSIPSP-PTIPIFGNLLQINS---
514A3P    -------------------------------------------------------------
514A4     ----MNTIFTIILTITILVLSLILKDLLFEGRIKKINKLIPGP-STIPVFGNLLQINA---
515A1    MILGIILGLFIYIYLINIKFFNRAVPSSLLVGENKLKCKFPSGP-LILPIIGSLYKLSL---
515A2P    -------------------------------------------------------------
515B1     -----------MATLLLVIIFMITFIIYKNFDSKRKNKYPPGP-INLPFIGGLYKLKP---
516A1     --------MIILLLSIIIFILYIVKIFKNKSCCGNEIILPPGP-ISLPFIGNLHQLAI---
516A2P    -------------------------------------------------------------
516B1     ---------------MYLILSLIIFLAYVAFHKKRTNGMPPGP-FPLPIIGNLHQLGK---
516B2P    ---------------MFLILSLIIFWAFVAFHKKRPKGLPPGP-FPFPILGNLHQWGR---
508A1     ---------MALFEIIISLFVVYIIHNAISKYKKIHVNELCGP-TPIPILGNLHQFG----
508A2     ----------MIFGIIGYLFLIYILHNAYSKYKRLNENQLPGP-FPIPILGNIYQLT----
508A3     ---------MEFLKLILFLIIFYIIHNTYIKFKKINKNELKGP-IPIPILGNLYQLTS---
508A4     --------MIMLIKVFVLLLVVYILHNSYKKYKKLDKNELKGP-TPIPVLGNLHQLS----
508C1     -----------------------MGPWGYIKNKRIHKNEAKGP-IGFPLIGNMIQIGK---
555A1     -------------MIIIVIVVFLFYFSFLNLNLNPKKKRPPSP-ITLPVIGNLISLLN---
508B1     ----------MLFNIFLYLFIFCIVSSGIKKYKKIHKNELSGP-FPIPLLGNLHQLGK---
508B2P    -------MIETFVFIFISILMFQFFIKCYILYRPKFKNELDGPSFPIPFFGNNLQIGK---
508D1     --------MVYLNNIFIFFIIFFIYSFVKKNKKSTKENDLKGP-IALPIIGNLFGLRN---
508E1     ---------MNIINIVIFLIIFYLFKSNYKKYIKKNKFEVNGP-FPLPIIG--FTSNY---
554A1     ---------MDLLLFIFFLI-LFYYSVKYYKADNQNSLSLSGP-TPVPILGNIHQVGK---
517A1     ---------MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGP-IAFPILGNVVQIRFWEL
517A4     ---------MEIVNVLLFLIILFLVKDFVKKNKKIHTKSPSGP-IAFPILGNVVQIRFWEL
517A3P    ---------MEIVNVFIILIILFLVKDFVKKNKKIHTKSPSGP-IAFPILGNVVQIRFWEL
517A2     ---------MRILIIIILIIIVFLVKDTIKKNKKVNSKSPCGP-FAFPILGNIIQYFFYQI
518A1     ---------MSILIILIISIIFYLIFDFLYKNFSN--RQFKGP-LALPLVGSLLHLKDDT-
518A2P    -------------------------------------------------------------
518B1     -----------MLTNIIILIILYLFYDFCYKNFKY--RNYGSP-WALPVIGHFIHVIN---
519A1     --------MESIINLIFYIIIFLILIDFLKKNISFRKNEPPRGGVAFPIFGDLPKLGE---
519E1     ---------MGIGLIILYLLIGLLAYDFTKKNKKISKNDPKQP-LAIPVLGHLHLFGS---
519B1     ---------MNLINLILYFILFWIVFDFIRKNRRISFNDPPSP-WALPIIGHLHKLSL---
519D1     ---------MNVFVLTVFICIIYLLFDLIKKNKKLKDEPPTPK-LALPLIGHLYLLGD---
519C1     ---------MNILLLIFYFLVCFLIFDFIKKNKVKKYDVPTLS-YALPIIGHLYKLGV---
519C2P    --------------------------------KIKKNDIPTLP-FALPIIGHLYRPGS---
519F1     --MEILTFIIYLITFFILFDFKKKKFKKNKRYSKSPNKEANGP-WSLPIIGGLHLIGD---
519G1     --MNYLLIIICIIFFSLFFDF-KIRKNWNLNFKRLFKKDVNGP-WSLPIIGGIYLIND---
519H1P    --------MFIIYFIFLFLLIISLFIDFIKKNLKKSNNDPPGP-ISLPLLGNLHNLTKN--
525A1     ----------MEDYSVQSVVSLVVFLLVLQILKYYNKTNKNNK-YNLP-KGPSFLKCQEEL
521A1     ---------MILLTLLYLIIFYIIIDFIKKNYKTKNQLPSPLG-IALPIIGHLHLLRT---
522A1     ---------MILTIVIIILTVIFVNKYLLNNGGKNDLRKVQGP-FNLPLLGALYAFDKE--
CYP51     --------------MIGTIAVLVIAILVIFAFKKSPSNIPPIV-ETIPFIGCFYQFAKN--
524A1     ----------------MKTPTKYFIIFILLAALAVFKGSLPGPSFVPPFFGMLFQLIFT--
556A1     -------------MFLTSILYTIIIILIFYKGLEYLIEKRSFP-LVHPIKGVMNGTKPYFI

513F1     ---NVVKSIDGFYKEFGP-VYRLRMGNIETVVLTGIDTLEESFLFNKHSFVDRFVKKSRK
513G1P    --NEPHLKIHEWYNKYGN-IFRIKMANIETVVLTEKPLLKKAFIDNSNLFKKRYLYLNKN
513E1     ---DPHIQFQKWYEKYGV-IYSIRLGNIETVVFTGYPIFKKAFIENSQIFAPRFQHLSRF
513A1     ---DLHLKLQEWYKQYGV-IYRIKMGNVETVVLTEYPIIREAFIGNSNSFVNRFQRKSRL
513A2P    ------ISFQEFYKQYGP-IYRIRMGSIETIVLTESSTLKEAFIGNSYIFENRFQKERNN
513A3     ---EMHLTLQEWYKTYGS-VFSIRMGNIDTVVLTEYPTIRKAFVDNSLAFASRYQLKSRV
513B1     --NGIHTTFQKWFKIYGP-IYSVNMGNKSAVVLTGFPIIKKAFIDNSEAFAPHYTFESRY
513C1     --KNLHLKYLEWFEKYGP-VFRVSIGSLETVVLTGYPILREAFIDNSDTFTSRFQRENAR
513E2P    -----NKVFKKWYKKYGP-IYRIRMGNIETIILTGYPIIKKSFIDNSNVFQKRYEYRSKI
513E3P    ------------------------------------------------------------
513D1     ---QVHEKLKEWYEQYGS-VYRIEFGSVSTVVLTEYATLKEAFVDNGEIFQSRFQRKSRT
514A1     --KDFPKSVNDFYERYGK-VFRLRLGSVEIVVLTGPEVIDECFNKKHREIFKERYIKFSR
514A2     --KDVATCFNDFYKQYGK-VYRLRLGSVETVVLTGGDIIDECFNKKYRDFLKARYVKFSR
514A3P    ------------------------------------------------------------
514A4     --KDFPKSVNDFYERYGK-VFRLRLGSVEIVVLTGPEVIDECFNKKHREIFKERYIKFSR
515A1     --KYPHLSFKQLSDKYGK-VFSLKMGSIDTIVINDINFLQKSFRDNPTFFSQRFHLPSFY
515A2P    ------------------------------------------------------------
515B1     --GKQHLSLNELYQKYGK-VFSMKFGSYDTVILNEPDVIVEAFHLNSTSFMDRILLPSFE
516A1     ---DPHLAIQKLMFKYGN-VMTVYFANIKTVVISDPNYLKEVFVNQSHKTSDRYLMGTSR
516A2P    ------------------------------------------------------------
516B1     ---SPYKSLKSFSDKYGG-LTTIFLGSVPTVLISEPNILREIIIKNNDSIIDRYISDSGL
516B2P    ---SPFKSLKSFSAKFGG-WPPIFWGGVPPVLIGDPNFLREIFIKN--------------
508A1     --ELPHRVLTKMTKKYGH-ILRVYMADMYTVVVSDPLLIREMYVDNSDIFTDRVKKPS-V
508A2     --NLPHFDLTKMSEKYGK-IFRIYLADLYTVIVCDPIIARELFVDKFDNFIDRPKIPS-V
508A3     --GLPHRDLTKISEKYGG-IYRFWFADLYTVVLSDPILIREMFVNNGDYFLDRPKIPS-I
508A4     --SLPHRDLSKMTKDYGD-IFRVWFADLYTVVISDPVLIRKIYVENHESFRDRPKIPS-M
508C1     --TKPHIELMKLEKIYNQRILKIWLGDYYSVFLSDIDLIKDIFINKFENFSSRPKSPLTR
555A1     --NQPQNILFNYYKKYGK-IYQLQYGIVNTVVLSEFDILKEAFIENGEVFIERYNKITKK
508B1     ---EPHYTLTKMHNVYGE-IFRLHFGDVYTVVVSDPILIREMFVDNHENFKYRPLLPT-F
508B2P    -NKILYFHKLENYFKKG--IFRVWIGEVFTVIISDPLIEKEMKKTIKEKPKYIKRDIF-I
508D1     ---DTYSIMDFYHKMYGG-IYRLWFGDYFVVSLNDPEIIREIFIKNYSNFSSRPFLPTIT
508E1     --IKPHIKCHELVKQYGD-IFRVYLGDNKTIMVSDYKIIEELFIKNHNSFLERPITPS-F
554A1     ---DAHLTIPIISKKYHG-LFRMWFGGTYYVVVSDYKLIREMYIENFENFKNRIATFK-T
517A1     FKIQEHELFGGYSKKYNG-VVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWR
517A4     FKIQEHELIGNYSKKYNG-VVRAWIGERLFLFVSNYDVVKYFQKDENFLYRPSLLVPGWR
517A3P    FKIQEHEL-----------IVRAWIGERLFLFVSNYDV-KYFQKDENFLYKPSLLVPGWR
517A2     LNIKEHSIIERYSRKYDG-ITRIWFGDIFILYVSNYEIVKCFQKEENFFDRPSTFVPTWR
518A1     HLVFQNDSKLYKDGDNNGKIIKYWFCDQLTLAIYDTNTMKEIYLKNPESLNTRVKSPSTN
518A2P    ------------------------------------------------------------
518B1     ---QPHLVVHNDRMKY-GRFVNYWFGDYLSIAITDPILYKKIYLNFPKQINSRLKSPTVL
519A1     ---NPHRYLTNLAMKKGG-IYSVWLGDEKVFILTDPEAVRDAWVKQFRNFSDHPKTKSVR
519E1     ---QPHRSLTELAKKFGG-IFTLWMGDERSMVITDPNILRELYVKNHLNFYNRASSESIR
519B1     ---NPHRSLTELAKVYGG-VYSLHIGDSKTVVITDVSAFKDVTIKQFKNFANRPQPKSIR
519D1     ---RPNRSFLELSKRYGG-IFKIWMGEYPTVVLTDPDHVNEVWCKQFLNFTNRPHFNSLD
519C1     ---NPHRNLTKLVEKNGG-IFSLWLGDIKTVIVTDPSINKEIMVKQFTNFSDRPRLKSFE
519C2P    ---NPHRDLTKLVEKNGG-IISLCLGDIKTVIFTDPSITKEL------------------
519F1     ---RPNRSFSELSKIYGG-IYKIWLAERMLMIVTDPEIIQDIWIKQHDKFVNRPHNITSQ
519G1     ---NPNRALTKLSKKYGG-IYKIWLGESFSMVVSDPEIVNEIWVKQHDNFINRPKNITHK
519H1P    ----PHRGLKNLSDKYGG-IFRCYLGDHYSIVVSDPVIINEIYIKKFEKVCTRPNNDTFK
525A1     -DTSENTVLKWFNQLNSD-NYSVSFFGRPMIFTRDTTISKYILSSNNIDNYTKPPDSSGV
521A1     -DPYKTLAKASKKTEHG--ILKCWNGEHLMVVVDNPSIIKQMYVN-TNNFTDRPQTKVFE
522A1     ---RFHKSFDKFYDKYKD-FYFIKFGQHDCIVLNSPKLIKQVVIEQSDSVFERFHTPSIK
CYP51     ----PLQLVRNSYDRLGE-IFTLHLMGFKMTFVLGPEAQALFFRGTDEELSPKEAYRFVT
524A1     -----PFSFYEKQEKYGP-ISWTSIMNKFVLFVTDAEINRQVFKEENAKLYLSLGAKKIL
556A1     -PFQRLLNLKPKLKELGS-IYFRWFFWYPIVEIKDINAIQYVYNEKSNNYSLYWNLNKSS

513F1     --INNGLDIIHSNG-EYWKILKTIFQTQMTPRKIKSYQFEIQSQVDLMAEQLYKSKNNDN
513G1P    ------AGIILSNG-EVHNKIKTAVLSTITNSKIKSIKDHHFNRELLKLIEILDEIANQG
513E1     -EANGCKNLIGSND-EIHSTLKKLILTEITSNKIKKMENHIVL-ECENLCKQLDKHCQDG
513A1     -KLNNGENLVIVNG-DIHNKLKTLVLSEMTNQRIKKYETSFIDNEIKKLFKVLDEHADTG
513A2P    -CENVLLANGEMF-------------------------------KLFKELDNLAEIGEPI
513A3     -VLTGAKDLAIQNG-EIHSLLKKVVLSEMTTTKIKRMEIHIIK-ETEKILKILDKHAERG
513B1     -KLNKCSDITQENG-KNQSALKRIFLSELTVTRIKKQESHIQN-EIVKLMKVLDKHSEDG
513C1     -SINGYKGLINSNG-DYHKNLKSVILSEMTATKIKKMESHINQ-ESKRLCELLDQHAKQG
513E2P    -NLIHCSDFPFTNG-ETHSNLKKIILSEMTLTKLKKQENYIIL-ECEKLCKHLDNHCESG
513E3P    ------------------------------------------------------------
513D1     -TCNKGLNLANSNG-EYFNHLKKTLSNEITNQKMKKNE-KIIKIQVGLLSEFFNEISGGG
514A1     -FFGKDYNIISSNG-DYHYVLRGILTSEITTRKLNNGRLESNK----FILEMFSNLCKDN
514A2     -YLGKDTNILHSNG-DYHFLLKGVLSSQVTVRKLNNGRLEFNK----YILQMFNNLNNND
514A3P    ------------------------------------------------------------
514A4     -FLGKDYNIFSSNG-DYHYVLRGILTSEITTRKLNNGRLESNK----FILEMFSNLCKDN
515A1     -YMGKYQGIIFGNG-SHWRKLKDILSSSITKSKSRQMEELFYNEYFKAEEYLLKKINQDN
515A2P    ------------------------------------------------------------
515B1     VVGKNQNIGFTQTE--YWKKIRGILNISLTKSKTRLLEGLFNQEYFRFDQFIKKQLKSKS
516A1     IIGNEKDILFSNGQ--YWKNYRQILAQSFLKLRDHKGITEKISLESVKLSQAFEWYATSG
516A2P    ------------------------------------------------------------
516B1     IIGGERNLLFSKGS--FWIKYRKIFSSAMTNARKFN-IASRIEQQAISLNNYFGTYANSK
516B2P    ------------------------------------------------------------
508A1     EHGTFYHGTVTSYG-EHWKNNREIVGKAMRKTNLKHIYELLDK-QVDVLIRSMKSIETSG
508A2     KHGTFYHGTVASMG-DNWKNNKEIVGKAMRKTNLKHIYQLLDD-QVDVLIESMRTIESSG
508A3     RHATHYHGIATSSG-EYWLKIRDIINKAMRKTNLKLIYDSLDQ-QVDNLIESMNKIESDG
508A4     KYGTYYHGTAASMG-EDWVRNRGIVSSAMRKSNIKHIYEVINN-QVDVLMSTMKKYEKRS
508C1     LGTNDFRGINGSSG-ETWFKNKNIIVNAMKRANTKTIYTLLDN-QVNDLIKEISKFESQN
555A1     FKS-SEN-IVNSNG-LIWKKLQSISIQELSPNIKIKKYEPMII-NETNKLIDSFNEHIKS
508B1     KFGAGGDHGLSLSN-ERWERTRELVQNAMKRTSIKKIYDMLDS-QVYELIKSMKQYQVTG
508B2P    ---------------------------LNLKSNLINLVFNEST---INLIQSMNCSIKNN
508D1     FGSFNYRGISGSNG-DYWKRNRNLLLNAMKKSNLKQTYDNLSD-SVNSLINLMKEFQSSN
508E1     SHCSDNQNGILLSN-EKWVNNREMIQKAMKKGIVKSVYELLNK-QINDLIQSVKPFSESG
554A1     MTGDDSRGIIGCNG-DIWDSNKELIMKSYKKVLNKDMNDFILL-KSKELFNFFEKNGIKN
517A1     YASSNGLGVMSSSD-DKWKRAKSSVSQSLR---VRTTKKLMEE-KAIEFIDSLEKISNNN
517A4     YASSNGLGVMSSSD-DEWKRAKSSVSQSLR---VHTSKKLMEE-KAIEFIDSLEKISNNN
517A3P    YASSNGLGVMSSSD-DEWKRAKSSVS**LR---VHTSKKLMEE-KAIEFIDSLEKISNNN
517A2     YMSSNGGGIMSSND-EKWKRAKTTFLKSLK---IHGKKYLIEK-KSIEFVNSIEKFSNSN
518A1     VIGNRFRGIVTADE-NYWQFHRDILMKSFTGRKVKS-LSSSIEKETIDLITYMKFIEKSG
518A2P    ------------------------------------------------------------
518B1     NISERFRGIISSNE-NNWDFHHGILSKLFNGHKAKI-NNFLFEKETKFIIEYMKKISKSG
519A1     IFSGNFNDMAFAEY-SQWKINSKWVSSAFTKTKLKT-IGDLIEKESNYFIEHLKAYSNSG
519E1     IYSGNLVDISFSVG-ESWKNRRRYVSAALTKTKVLN-VITLIEEQANFLINSMQYYAKSG
519B1     VITN-FKGLAFADY-DQWQKTRKLVSSALTKTKIKT-FNNLIEKQTENLIESMNEFSNKN
519D1     QFSSGFRNLSFSDY-PLWSELRKLVSSSFTKSKVKG-ISNLLETQTNYLINTMNNYSINN
519C1     SFTGGGVNLIFIDYNEKWPVIRKIVSSSITKTKIISNYKEVIENQTKILINSMRTHSKIN
519C2P    ------------------------------------------------------------
519F1     IFSLNHKSLVFGDV-DEWNKVRPKMTCHFTKIKLNSTK-QIVNDQLKKMLKIMTTHSLDS
519G1     MFSSNYRSLNFGDN-PNWKFNRSMASSHFTKTKLLSSK-TVVEKKLNKLIETMEYHSINK
519H1P    MFSSGFKDLAFSDNYNIWSKIRTIVNSNFTKTKLTKTIYNYLEDQTNQLIENMGNYSKSG
525A1     LIRLAQNSILMSEG-DQWRYHRSIINQPFSSKNVKLMIPTIITTINKLINHLTIIIDIHS
521A1     IISRNYKNSGFANG-EKWKHLRGLYAPSFTKIKSRPHENIILK-YVNFEIKSLKNHAITN
522A1     RYAQGKSILGCSPD--EWKKLRSFIVISFSKNKMGQQVLDKIFHTQYLKFENHIKKLIKS
CYP51     PVFGKGVVYDSETE-IMYEQLRFVKNGLVLSQLKKAVGIIQEETEKYFETKW---GDSGE
524A1     TEKAIPFIEGAP-----HRQLRKQLLPLFTIRALSSYLPIQESIVDEHIAMWIKNGKADI
556A1     NFILTGSEIKRFFR-IYYWAFNCKDSLQRIMPVIKSQVFDFIHSHKFQNSTLSTNDDVTN

513F1     IVTNI--NENMKFMLFNIMSILIFGKQSIYCNNT-KDDDDVDKEKKHIIFSIGRFFKTSG
513G1P    KPVQL--ISLIKQFTLNITCSLIFGFSFPI------KVENDGEASKLVNGVNNFLN----
513E1     LPFSL--NMYFKLFSLNIILRFLFGTINN-------SYQDKSNQ--DIVDVIIEFLHYGG
513A1     KPIIL--NNHIKMFSMNIVLCFTFGLNYSY------PYDEFEKAS-EFIKLMVEFFNIAG
513A2P    ILNRY---IKLISSNVMLTFTYGDKLLY--------KYNEIETFE-EYLKNLSNYLKVTG
513A3     EPFII--NNYLNMFSMNVILRFLLGIDY--------PYENVDETV-GYVKSIKSFFAVAG
513B1     KPFLL--NNYFSMFSINIISRFLFGIDF--------PYQDFEETS-DLMVGIRDLLIASG
513C1     TPFTM--NKYLNLFSINIILRFLFGVNY--------PYTELDDGSSSIIQVIQQFLKLVS
513E2P    LPFKF--KFYGKLFSLNIIFRFLFGLNY--------QYDNEKIIE--IINLILELVEGAG
513E3P    ------------------------------------------------------------
513D1     -KEPI--NNIIKMYSLNVMLSLLFNIHF--------PYNNNSYQD-ELMSTITRYFKSTG
514A1     KE-------TLVKNTPNQIRILAVKLILNFTL----GIEENDETILIIVEKIKCIFEAAG
514A2     EGSTM----FLANDVPSQIKKLILKVVLNFTL----GIEENDDINLSLFQNGSNIFKAAG
514A3P    ------------------------------------------------------------
514A4     KE-------TLVKNTPNQIRILAVKLILNFTL----GIEENDETILIIVEKIKCIFEAAG
515A1     NIDMGP---IFKRILLNILYRFLF------------GVSFEYDDNLLSKEFYSFIQSYNK
515A2P    --DMGP---IFKRILLNILYRFLF------------GVSFEYDDNLLSK*FYSFIQSYNK
515B1     DTMFIR--PYLKRLSFNIIYSYLF------------SETIPYEDELIPSDILDFIHASEE
516A1     QVVNP--CSLFKMYTLNVIMQLLYSHRSSY----------DLKGQHPIIDALKMVEESLA
516A2P    ------------------------------------------------------------
516B1     QAIN---HDYIRRYSLNGVIDYSFSDSVEY----------ESDTHHIVIRAAEIMEEILA
516B2P    ------------------------------------------------------------
508A1     KTFDT--RYYITKFTMSAMFKFLFNHDIPE------DEDINKGDTQKLMGPMSEVFQNAG
508A2     ETFDP--RYYLTKFTMSAMFKYIFNEDISK------DEDVHNGQLAQLMKPMQKVFKDFG
508A3     QVFEP--RIYFKKYTMAAMYKFIFNEEIN-----------FNNEISELIGPIEQVFKDLG
508A4     EPFEP--RYYMTKYTMAAMFKYIFNEDIGE------DEDIHTGEIQKIMGPMNQVMEDFG
508C1     KSFNP--KYYFRKFVLSTMFKYIFNEDVPY------DENLENGKLSELTMEMENIFKTLK
555A1     NESID--PTLNIKICFLNIIISFLFNFRY--------NDYKDEKVIQLVDYIHSIFRMGS
508B1     NPFEI--HLYAQRFTLSIMFKYIFNEDISY------DEDITKGKIAELVQPMDQIFKSLG
508B2P    KEFEP--KLLCSIFSFSIIFKLLFNIDLKN------ENYKEIKKIMKLVNEIN-KEKSNS
508D1     ESFQP--DMYLRKYALTTMFKYVFNETVSF------ENKIVQGEEAELIDNINEAFNFMT
508E1     EPLNF--RLFATRFTLSTMMTYIFNEPLSY------NENLENG--TVLYMFLENIFVLAD
554A1     E-INN-TRFYFQSLTLTVMFKMIFNENKSF-----QLYSDSTEFKLIFKTILNLLNSLNV
517A1     EIFYP--KGHIQGYACSMLFKYMFNQDLS----------VESGMSRTIGNAVEHVFGNLS
517A4     EIFYP--KGHIQGYACSMLFKYMFNQDLS----------VESGMSRTIGNAVEHVFGNLS
517A3P    EIFYP--KGHIQGYACSMLFKYMFNQDLS----------VESGLSRTIGNAVEHVFGNLS
517A2     QVFYP--KQYSQGFTSSIFFKYMFNEDIS----------IDNKFLKEIGTAVGMVFTKNS
518A1     QSFSP--RSNFMNFYSNIIFDYVFSRRIE-----NIYEGVNEEQGK-VLLAIRELFDYLA
518A2P    ------------------------------------------------------------
518B1     ENFDT--RSNFLYFYSNILFDYILGKRVE-----NIYENELRKDRKKFMVSIQEVMDSVG
519A1     QPIFP--KPYISKFGINVISGMMFSQVIS------KDESVDKGAMEKLTVPIQAVFKRLG
519E1     EPFFP--HKYYNKYTMNIVMSIGFSKTIS------ENESVEEGPISQLIIPFYNILENLG
519B1     ELFHP--RKYLTKYSLNIILSMLFSKEIG------KNESINKGTMERLTIPFNEAFKKVG
519D1     KPFNP--KKYIHKLTLNVVCMIAFSKEIK------NDEDVNEGDMARLTKPKEMILKHLG
519C1     EPFKS--KKYFGKFSISIVLGIMFKQDNDEKQININDNNIDNDPITKLTEPIQQVFLLLG
519C2P    ------------------------------------------------------------
519F1     KPFNQ--YVYLNTYSMNIILGLMLSIELPHS-----NSNDKDGQFSKVLHSIDEIFKSIG
519G1     LPFDS--YVGFSEYSLNIILNMLVSMDIDEC----------ENSTQNVIYSINEIFKMLS
519H1P    EPVFLSTITIYMKISLNVICKLFFSKEILQ------NESFDNGKMRRIAVPIQIVCKELG
525A1     YCTKLTFDIIGKLSIGYDFNSIESSDNDNDNNDDDDISKQFDFILNEMIRPIRRFSSYLP
521A1     SIYNPFLIENINSFGTKVITEIIFGREFSE------------NEVYSLIGPMNKLFGILD
522A1     NNNIVTLEPEFKRLTISIIFNFQFGTDLEFT----------DPLIDSLLVCTEKIIASCQ
CYP51     ----IDLLYEMNKLTILTASRCLMG----------------KSINKSLGQSGQLADLYHE
524A1     NARNN--CRDLNMAISTGVFVGNNTPES-------------------VRDDIAKNFFVMN
556A1     ---------FMLKLLSRVYLGSSDEAYHC------------FKANYKKFNKSYLDFFHYL

513F1     SLFYSDFIPILLPFDL----INLSRNNFFKDFQVLTNFVSKNVN-QQLSKLNDNNN-NNK
513G1P    ------------------------------------------------------------
513E1     NPIMSDFIPILKPFYK---QNKFFKFYP-ILCDHLNKLIENYKNNK--QLQKQQKQQQNE
513A1     QPIISDFIPSLEPFID----TSNYLNTYKRIFNYTSDLITKFKN----ENEIHNNI-NDN
513A2P    RPILSDFIPFLKPFSK----NVNIEEWDDFFYINSNKYIEKFK----------SGK-NSK
513A3     LPILSDFIP--IPLKK----SGVFFDSYKELEIETDKLIEKFK-----KSRNEKIE-NGT
513B1     EIVLSDFLP--IPHSK----RSKLYTSYQALVVQIETLVKSHK-----------------
513C1     QPSITTYFPILSPFMND--RSKEFYDIHKLLSNHIINLIERYKDSK--QHQQQEQE-PID
513E2P    DPIISDFIP--LVKYF----ENINQNKFLKIYKKLIILIENIINNL--KLKFIENN-YDD
513E3P    ------------------------------------------------------------
513D1     LPYPSDFIPILYPFLKN--KPKEYFEDYESVKKLITRITNEYQLKH--MTEISNKS-TIE
514A1     LLIYSDYLPFLFPLDIKSMSKNDIISSYFFLKDFIGIKLDAIKIKYEKENELKNET-TDE
514A2     LFIYSDYLPFLFPLDIKSMAKSNMISSYVFVRDYLAKKLEEVKKKEYIIN-----G-DDD
514A3P    ------------------------------------------------------------
514A4     LLIYSDYLPFLFPLDIKSMSKNDIISSYFFIKDFIGIKLDAIKIKYEKENELKNET-TDE
515A1     LFEYLAKQPADFIPILKPFNNYKEIEKEYNNCLNFFQPLIDNILKNISDD------DDDG
515A2P    LFEYLAKQPADFIPILKPFNNYKEIEKEYNNCLNFFQPLIDNILKNIIDD------DDDG
515B1     LLVVLSRMPSDYIKVLRPFESHKKIKEICDRMSKFIKPRVDKKVELLDQD-------NPK
516A1     VGNVLDLFPILNIFLKKNKLKLVNNLQQVWSYSQDSIKEHREKLLIN---------PEKI
516A2P    ------------------------------------------------------------
516B1     TGNPHDYLPFLKPFYTKKRNTLAMAVGQVWDYCNDAITVHRKTLDH-----------EKP
516B2P    ------------------------------------------------------------
508A1     RGSLFDVINITQPLYLLYLEMFDQSFKDIMKYHREKYNEHLKTFDPD-----------VE
508A2     TGSLFDVLEITRPLYFLYLEWFTSHYYQVINFGKMKIYKHLETYKPD-----------VQ
508A3     SGSLFDVLLISRPLYYQWIEHTDKNYPKILNFLKKKYHQHLKTYNPE-----------IQ
508A4     TGSLFDVLEISQTFYLKWLELTEKNFPLLLKFFNGRYEQHLETIKPE-----------SP
508C1     VGKLANSIEILETPYYYYLQKTDKVFKNIKKLIIEKYKNHNLSINPE-----------KP
555A1     -----HPIPQDYIPILNKFYINKTTKIHQKIFENIYEYIENQVQKRLEILNKNN-NNNIN
508B1     SGKLGDFISIAQPFYYQWLKFSDKQFNGPFSTVKKFIYKRYLEHINT-------IDHDNP
508B2P    SDLNSITNFIENQFYYHISNIDQRLVDFFFFYNLIINNIIYNLYFNL----------ISL
508D1     LGNAGDFFKILQPLYYQYLLYRGGCFNRIRTLIRNRYIEHRKTIDIE-----------NP
508E1     VGHIGDYISFLKPIYSLFLKLTDSNVPLARDYVYKKFYEHLKTIDNEKE---------EN
554A1     YNVIYDFLGIFQPILLKFTKILDKNSFLSKIATEKFNSRIKEIDFTSDDFKAN-----DL
517A1     KLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPS-----------KP
517A4     KLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPS-----------KP
517A3P    KLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHFKSIDPS-----------KP
517A2     HLTVFDCFGILSPFYDLFFKFRLRPIEILKKTIDKQLTNHLNSMDSKMGDH-------QS
518A1     DTLIVNYLIFTKPFYFLYLKMFGHPADSLKKILTKYYLEHFESIDLN-----------NA
518A2P    ------------PFYFIYSKIFGHPSDPLKNIINKYY*EHCETIYID-----------NP
518B1     LIKFLNYLILSYPFLSIYLRYFTYTTFNLKKILKQYYDEHLETIDLN-----------KP
519A1     ADNLDDFISILQPVFYFQNEKFKRQVQEIYDYLEGIYNQHDTNLDT------------EN
519E1     SGNLGDYVWYTQPFFYFKNKKLEQDTKKVYTFLEEIYNEHIKNLDE------------SN
519B1     --KVDDFLWFLSPFFYFSNKQYKKYIFDIYYFMEEIYDQHLLDLDY------------NE
519D1     SSNFCDFVPLVRPLFYLKNKRFDQTLKQVIEYIKEIYDDHLLNLDLN-----------SS
519C1     TGNISDFIKILRPFFKNEYKKLNNSASKVFKFMEEIYDQHLLKFDK------------SN
519C2P    ------------------------------------------------------------
519F1     TNGPEDIFPTLLPFFKNRISTFTNHLNVIKDFIRSIYKQQIKTFDIN-----------IE
519G1     TNSPQYSFPYLKFFFKKDLNNFKFHLDKIKSFIHSIYLKQLESYDP------------SN
519H1P    AGNFGDFVGILSPLLYFTKKKYQKNSSTSTDFIGEINDEHLKNLDHD-------------
525A1     -LYNDIKLFKFLNELESIIKGAINSRSLITDNNNNKTYKKNFLLDNL-----------LD
521A1     TPFPSESISFLKPFYRRSYKECDKQCEELFKLVEKVYDDHLLNLDKD-----------NP
522A1     KASDLMPIFEIFTSYKDIDGVVKEMYALVKPFLEKYLKQHDRNNPKC-------------
CYP51     LEEGLNPISFFFPNLPLPSFKKRDAARAKVAAIFHSIIQERRRSTDD-----------SV
524A1     EGFLCLPIDLPGTTLRKAINARVRLVEIFTDIIAKSRKRMGDGEKPQ-------------
556A1     ---FPTLLKIPSKFLRKYIKNKNKRALYQVLAMKAYYGVVKQSSDDH------------I

513F1     EKEGEERKSIVEAYLENYLNGEIKFESVLSSCTNLLLAGTDSSANT--LSFLLVSLINNP
513G1P    ------------------------------------------------------------
513E1     DDDDDDDGTIIGKLLKEYHNGKISWTSVVSTCVDVFLAGVDSTSNS--TIFTLIALVNNS
513A1     NKSLADKP-ILSKLLQSFENGEISWDSVVSTCIDLQTAGADTSANT--ILYCLLELINNP
513A2P    QSKTENKP-IISKLLSLYENGEISWASVIGSCIDMQASSTDT------IMFCLIELTNLK
513A3     YNEEEDES-ILSKLLKEYEHGNITWECVSHTCIDIISAGTDTSANT--LVMALIELINNQ
513B1     -YKEDDEC-MLSKLMIEHDKGNIPWDAVISNCNTIITAGSDSTSST--ALFFLIEMMNNP
513C1     GATEPTVT-ILDKLLIEVENNRITQNALISICIDVLIAGTDTVGQT--LSFAIVALVNNA
513E2P    DNDENNIT-IFLKLFKEFKNGKITWDNLVGTCVDLTVGGTDTVSDS--LNFSLIALINNP
513E3P    ------------------------------------------------------------
513D1     EIENYQPTNILESLLKQYRLNKIPYDGVIGCLMDLILAGSDTTGNT--CLFSLVALVNNS
514A1     TSSKLNNIPIIENYYKNYLDGSIHYDSILFSISDIIFAAVDSTSNG--FSLLIGQLINKP
514A2     GGVDTSQTPLIESYYKLYLQGLIGYDSILLSIVDIIIASVDTTSNS--ISFIIARLTNHQ
514A3P    ----LSGIPFVEDCYESYLDGSVRYDSFLFSVSDVVFAAVDSASNG--FSLLIGQLFNRP
514A4     TSSKLNNIPIIENYYKNYLDGSIHYDSILFSISDIIFAAVDSTSNG--FSLLIGQLINKP
515A1     NEPKCFLEYFISEIRKDTS-NLIKITDLPYICFDIIVAGIVTTSTT--MDWMLLYLTNYP
515A2P    SEPKCFLEYFISEIRKDTS-NLIKITDL-------------TTSTT--MDWLLLYLTNYP
515B1     CFIDYLILQI----RSDPSQ-TIKIDAIQYIVLDLLVGGTDSTSSA--LEWMILFLSNHE
516A1     DDLLDLFINEIKLSKNSEFFD---DEGLYRVCSDLLLSGTETSSST--MSWLLLFLINNP
516A2P    ------------------------------------------------------------
516B1     RDLLDLILMEIEKSEEKQFYD---DDSLSKCLTDLIVAGHETVAIT--LGWMILFLSNHQ
516B2P    ------------------------------------------------------------
508A1     RDLLDILIKEYGTDNDDKI-----LSILAT-INDFFLAGVDTSSTA--LESMVLMLTNYP
508A2     RDLMDLLIKEYGTETDDQI-----LSISAT-VSDFFLAGVDTSATS--LELIVMMLINYP
508A3     RDLLDLLIKEYYSGSDDDI-----LTIIAT-INDLFLAGTDTSSAS--LEYMVMMLVNYP
508A4     RDLLDILINEYGTNTHDDY-----LNIAST-VLDFFFAGTDTSSTT--LEYLFLMMANYP
508C1     RDLLDILINEYGT-TDDDV-----LNITQV-TLDMFMAGTDTTANT--LEWIIIKLCNSP
555A1     ECFVDLLLLKFKSNLLTW------NEVIKT-TTDLMIAGSDTNSLF--TIHLIIALTNRE
508B1     RDLMDLLINEFSNDKNLI------PTILQT-SLDMFLAGNDTTAAS--IIWFVLRMQEHP
508B2P    KDFMDIIIYKENSFETKEK---IKKQVVYK-CTDYILNKSESISKV--IENFFVLIAQDQ
508D1     RDLLDLLIIEYGDHSDEN------MISIVQVCFDVILAGVDTLASS--LEWFLVMLCNNQ
508E1     YDLLHTFIKEVGIKDKES------VKSIVSNSLDLLVAGTDTAAKG--IEWIILRIANNQ
554A1     LDSLIMTINEDENGLNEKQ-----IENIKSICIDFLMAGTDTTGST--IEWIILKLVNNP
517A1     RDLMDDLLIEYG-LNEITK---EDTMQINQICFDIFGPAVGTVTIT--MNWVILQLCNRP
517A4     RDLMDDLLIEYG-LNEITK---EDTMQINQICFDIFGPAVGTVTIT--MNWVILQLCNRP
517A3P    RDLMDDLLIEYG-LNEITK---EDTMKINQICFDIFGPAIGTVTIT--MNWVILQLCNRP
517A2     RDIMDDLLIEYGSLNEISN---QDRIQINQICFDVMSTDIGTVATT--IDWVLLQLCNRQ
518A1     RDVLDSLIIEYRKVGGK-----EEQSSIIPMVNELILAGTETNSST--AEWFILTMVNNL
518A2P    RDVLDSIISEYRKVNGK-----EE------------------------------------
518B1     RDVLDNLIMEYKNQNAI------ECDKSFVAIAIELLAAGDTNSST--SEWFLTYLVNNP
519A1     PKDLMDLLIISTEGK--------ERDMIIHIGMDCLLAGSDSTSAT--CEWFCLFMINNP
519E1     PRDLMDQLIISTGGK--------EKDMVIHVSTDFLLAGSDTNAST--LEWFCIFLANNP
519B1     PKDLLDQLIIASQGR--------EKETVILVGMDFLLAGSDTQKAT--QEWFCLYLINNP
519D1     PKDIMDLLIMSTNDS--------KEDIIIHTCIDLLIAGSDTVGVT--FRVFRFIYPNNP
519C1     PRDLMDYFIEYEFTNSPNTTLEEKKISIIKGCMSFVFAGDDTVAAT--LEWVCLYLINNP
519C2P    ------------------------------------------------------------
519F1     PRNIMDCLISEYYEDDDQEDEVAKQELIIQLCIDMLVAATDTSAST--LEWFMLFMINNP
519G1     PRNILDSFISDLQSNDI--------DILLQICIDIVVAGTDTVANL--LQWFVLFCINYP
519H1P    PKDLMDMLIIDST------------KGKDEDKEPIVHIGYDFLMVD---QIRHL-VLWN-
525A1     -----------DNVK--------EKDII-GNINTFLLAGHETSANL--LTFIFYLLSTHN
521A1     KDVMDVMIVETDFKE---------KDHVICICCDLLMGTKDTFNTI--VLWFFVLMINYQ
522A1     --ALDHMINCILDQDEPKL---ITYEHLPHFLMDMFIGGTESTART--MDWFTLMMTNRK
CYP51     DDVLYTLMNSKYKDGSVLE-----DEQIVGLMIGLLFAGQHTSSIT--LTYTIFYLLNNL
524A1     --SLIDLWVEHFLNCPKEERDELSNDTIIFTLLSFMFASQDALTSS--LVWTVQLMAEHP
556A1     EESMINIIAETSYNDKEGL-----SLEEIKMPSYLL------NASS---IKGPMIMVENL

513F1     EIQEKVYNEII--------------------TNLKNDEISINDRFKCPYTCAVIKETHRL
513G1P    ------------------------------------------------------------
513E1     NCQEKLFNEIKNNLKKSDDGHDE------------IVIRHSLYRSSIPYLSLVMKEVYRL
513A1     NIQSKVYDDIKQAIIQSKENENQNDNENQEQTEEIITLSFNKYRTLAPYLSMVVKETFRK
513A2P    NIQNKVYNEIKQEIKKQNINNNNNEDE--------VLIQYNKYRNSLPYFSMVIKETFRK
513A3     EIQSKAFSSIRSSCLNDSNDDDDDDE---------IVITHSKYRSLLPYISMIIKETFRK
513B1     TIQTKVYNDIVVSFEQNQQADDYMNES-------MVILKYSKYRSLIPYLSLALKENYRK
513C1     EIQEKLSRNIIDSMEKGDN-----------------HYSYSKYRNGIPYLALVVKEVFRM
513E2P    NCQEKLYNEIKNELLKNNNNNNIDDL---------IILKHSLYRLSIPYLSMVMKETYRN
513E3P    ----------------------------------------------ITYPSMIMKEVYRL
513D1     NIQEKLFNEISNAFNDDDGDELNGANDISN---SLLKLSYFSDRIKTPYLVAFIKEVKRY
514A1     EIQDKIYEEIMRNDENNNTNN-----------------ISFADHTKYPYIISVMNESYRY
514A2     EIQSKIYEEIMSNDINNNSNN-----------------ISFSDHSKYPYIISIMNETYRY
514A3P    GIQDGIYEGIMRNDEVSNADD-----------------MSFADRAECPCVFSVMDESYRF
514A4     EIQDKIYEEIMRNDENNNTNN-----------------ISFADHTKYPYIISVMNESYRY
515A1     NIQEKLFFEINTPN-----------------------HPLHKDKLQFPYLNSIIKETLRI
515A2P    NIQEKLFFEINTPN-----------------------HPLHKDKLQFPYLNSFIKETLRI
515B1     SIQEKLYNEICKNTNTNTTATTTENDNESY-------FPKLIEKNNYPLFNACVKETLRR
516A1     NFQDKVRTELLEATGGKK-------------------TIGLTEKSKTPFFNACIKEALRI
516A2P    ------------------------------------------------------------
516B1     DVQQKVYDELINVVGKGN-------------------LPALVHRKDTSYLNACIQETMRI
516B2P    ------------------------------------------------------------
508A1     EIQEKAFDEIKTVVNG-------------------RSKVNLSDRQSTPYLVAVIKETLRY
508A2     EYQEKAYNEIKSALSSNGGGGGGGL--------TQRNKVLLSDRQSTPFVVSLFKETLRY
508A3     EIQEKVYDEIKLTVNG-------------------RNKVLLSDRQFTPYTVSFIKETLRY
508A4     EIQDKVHQEVKSYLKQIG-----------------KDKVELNDRQSLPYVVAVIKETLRF
508C1     IHQEIAYNELKKVVSSKVIIDDS-----------IKREITLSDRPNTPYIQAIIKETMRM
555A1     NIQNKVFNEILNFYILN-----------------ENNKITFSNKSKTPYYNSVLKEVERR
508B1     EIQLKAYNEIKDAVGD-------------------RDRVLLSDRPKTPYLNAIIKEILRL
508B2P    DYQYLAFNELKSVINTKLLYNGVG-----------ENIIKLSDKSYTPITNSICKEVLRL
508D1     QIQDTVYNELKETVVG--------------------PVVTLNDRPSTPYTMACIKETIRL
508E1     DVQELIFKELKSIVDSCG---------------RVEDRIYLSDRSSTPYLNATIKESMRI
554A1     EFQELIFQELKKLNKSEI---------------------PAKNKINTPFLNSFIKETNRL
517A1     ELQEIAYQEIKKAVKDDE-------------------YVNLNHKQNAPYIVAFIKETMRL
517A4     ELQEIAYQEIKKAVKDDE-------------------YVNLNHKQNAPYIVAFIKETMRL
517A3P    EPQEIAYLEIKKAVKDDE-------------------YVNFNHKQNAPYIVAFIKETMRL
517A2     DLQEIICNEIQDTIKIKRNNVINDGGGGAD---TDNLFINLCDKQSIPYLIAFIKETMRV
518A1     DYQDKIYNELKSTLET------------------TTAMIKLSNRNQTPLFNAALKEVLRL
518A2P    -----------------------------------CSLINLSHRPLTPLFNASLKEVLRL
518B1     IYQDKIYDELIGALKINKPLKG------------SDVLINLSHRPLTPLFNATLKEVLRL
519A1     DVQKKAYQELINALKD-------------E---DNKKFIPISKKDNCPYMLSIFKEVLRL
519E1     EIQKKAYEELISVVGK------------------DCKAVTTKYRDDCPYLVGAIKETLRM
519B1     DVQKKAYQELISVVG------------------KDCKFVTSNHIENCPYFISIIKEVFRI
519D1     IIQEKCFNELFNAFSNSNNTDNNNNNST-I---TAAIGFGDEYSSKTPFLNACIKEVLRI
519C1     AIQEKCYNELISVLGDNNNE-------------SKIKFISLKERDNCQYLINVIKEVLRI
519C2P    ------------------------------------------------------------
519F1     NLQEDLYEEVVNVVG------------------KDCPYVTFDDVPKLALIKACYFEILRI
519G1     EIQEKLYNEIIEVVG------------------KDCKVLKYEHISKMPYLYGCFRESLRI
519H1P    DCQEKAYNEIVSVMG------------------EDCNKISYADRPKLPYLVACINECLRM
525A1     NVQNDLYNHLIENQKKKIN-------------KDNKFTEEDEDYQSIEFLDWVIYETLRL
521A1     DVQLKGYQEIIKVLECTG-----------------RDHVTIEDIDKLPYIDGIIKEISRI
522A1     EMQDRIRTELLDVGIRLP---------------------VLVDKQKYPLLNASIKEIHRL
CYP51     EYFDETQKDINDIVQKENQ-----------------GEINFDGLKRMNRLETVIREVLRL
524A1     DILAKVRAEQASLRPNNE-------------------KLDLDTMRQATYTRMVVSEILRF
556A1     MFQLIEKSEIESKIRKEIKLVFE-------KNGKDVNSFDFDDIMEMKYLEATLDEINRL

513F1     YSIAPLSEPHYC------SNDVEIKG--FKIAKGTQIIQNIYSSSRSEQYWDK-PLSFIP
513G1P    ------------------------------------------------------------
513E1     YSVILIGLPHIT------SEDVEIEG--YKIAKGTQIIQNVFSTHLCEKTFPM-SKSFIP
513A1     YPSGTIGLPHVT------SEDVELNG--YKICAGTQIIQNIWATHRNEKQFSE-PDSFIP
513A2P    HP----VTAHET------SNDVEFRG--YKISKGTQIIKNIWATHRNEKIFQS-PNSFIP
513A3     HPIALLGLPHVT------TEDVEIDG--YKIEAGTYIIQNIFSSHRSDKIFQS-PNEFIP
513B1     HPAAPFGAPHET------TQETVIEG--YTIAKGTMIFQNIYATQRSDTFYSQ-PDEFIP
513C1     YPAGILGLPHMT------SEDCEIQG--HKIAKGTQIIQNIYSTHRSESFWPN-PNNFIP
513E2P    FPVALLGL----------------------------------------------------
513E3P    YPVGVLGLPVLI------DNDIEIDG--FKIKKGTQIIKNFYQSHRHEDFFKL-PNHFIP
513D1     YPCAPLSVPHLL------TEDCEIQG--YKIAKGTQVIQNIYSTHLSQSFCSN-PLEFSP
514A1     NSSVPITEPNKT------TEDVEVNG--YKIAKGTMIIKNLRGTHLSKEFWGEDALEFKP
514A2     YASVPLPEPNMT------TEDIEVDG--YKIAKGTQIYKNIRGTLISKEFWGEDALEFKP
514A3P    YSSVPITEPNVA------TGDVEVNG--YRIAEGAMII-NLRGAHFSRGFWG--------
514A4     NSSVPITEPNKT------TEDVEVNG--YKIAKGTMIIKNLRGTHLSKEFWGEDALEFKP
515A1     SPPAPFALPHIC------TDDIVIDD--IFIPKNTQVIPNIYGCNRSNIESSE-SNVFNP
515A2P    SPPAPFALPHIC------TDDIVIDD--IFIPKNTQVIPNLYGCNRSNIESSE-PNIFNP
515B1     SPPVPLGLPHLC------SEDTEIGG--YLIPKGTQIISNIYSASNCDKVFTD-PLEFNP
516A1     RPVGALSLPRIA------SEDVTCGP--YTIEKGSQIIMNVYGLAMDPTVWED-PETFNP
516A2P    ---------KMA------REDGTWGP--XXXRGGQIKKERVRGLGRGPTVWGG-PETFLP
516B1     RTAAPLALPRIA------SEDIKVGG--YTIPKGTQVMMSVYGMASDERYWKD-PHIFNP
516B2P    ------------------------------------------------------------
508A1     KPMSPFGLPRSS------SKDCMIG--GHFIPKNAQILINYQALGMNEEYYEN-PEQFDP
508A2     KPISPFGLPRST------TSDIILNN-GQFIPKNAQILINYHALSRNEEYFEN-PNQFDP
508A3     KPPSSVGVPRTT------SQDIIIG--DKFIPKDAQIFINYYGLSRNQDYFEN-PEQFEP
508A4     KPVTPFGVPRSC------VNEITIDE-KYFIPKGAQVIINYPSIFENEKYFKN-ANQFDP
508C1     HPVVVFGLPRYC------ENDIFIGDENYFIPKGCKVFINFHSIGYNEKYFKD-PYKFEP
555A1     FTVSPLSQPHRT------NKDIILNG--YFIPSGSQIIQNVYSCHLNDKDWEN-PFQFNP
508B1     NPVGPFGLPHRS------SNDIVIGNGKYFIPKDSQILVNYRGLGFNEKYFEN-PSQFDP
508B2P    NPVDQLSSPITC------KKDSLVNG--YFIPKDSQIIINHKSMNLNEKYFND-PFNFNP
508D1     KAPAPFGLPHTT------DQDIIVKG--HFIPKDSMVLINFYSLGRNPKDFPD-PLKFDP
508E1     TPITPYGIPRVV------GKDLIIKG--HFIPKGSHVVINYRALNHDESIYKN-PNQFNP
554A1     YPIAPLSLPKSN-LNFGIINEMIIGDNKYYIPANTNILMDVKGFSLDENNYKD-PNEFKP
517A1     CSNG-FGLPRTA------KNDQICGD--FFIPKDAIIFINYLEISQNEEIFKN-AKEFNP
517A4     CSNG-FGLPRTA------KNDQICGD--FFIPKDAIIFINYLEISQNEEIFKN-AKEFNP
517A3P    CSNG--------------------------------------------------------
517A2     FSNG-WSLPKTS------KHDQICAN--YFIPKGSILFINYFSIHLNEEFFKN-PREFNP
518A1     YPPVPFGVPRQVN-----QSFEINGGS-LKIPKGTQIIQSLYSIFRDENYWDS-PDQFKP
518A2P    YPPVSIGVSRLVI-----EEFTIDNGK-YTFLKGAQIIQSLYSIFRDEKYWSS-PNEFIP
518B1     IPATP--FSVPRM----SNEGFEVDG--IKIPKGTYLFPSMYSIFRDEKYWGENANKFYP
519A1     RPVGVLGIPRVA------LEETTIMG--YTIPKGSQIFQNVYGMS--HLFVSD-PYKFKP
519E1     RTPAPLSLIRVS------EEDFMTSGG-IFIPKGTQIVPNLYGIG--QNFVDD-PSSYKP
519B1     RSPGPLGLPRIS------IDDTYLSNG-MFIPKGTQILLNIFGMG--NLLVSE-PDQFKP
519D1     KPVTSLGLPRIA------NDDTFVNG--YRIPKGTPIIENIYGLSNSDQLIDD-PTTFNP
519C1     RTPLPLSVPRIA------TQNCEING--FFIEKGTQILSNAFGMS--HLYVDE-PNVFNP
519C2P    ------------------------------------------------------------
519F1     RPVTSLSLPRVS------MEDTTTLN-DIFIPKDTIIIQNIFGMGNSEKFVSN-PTVFNP
519G1     RPVTPLSLPRVA------KCDTYIKD-DIFIPKGATIIQNIFGMGNDEKYISE-PNKFKP
519H1P    RTEDPLGIPRGA------VEDIEING--YFMPKGAKVHHYLYAFGMNETVFEN-VNKFQP
525A1     FPPAPMIGRTSK------NDDILKSG-NISIPSETLILISVYAIHRDPKLWKD-PNIFNP
521A1     HPAGPLSVPRTA------INDIMING--YFIPKGCHVFQNTYGAVYNYMKESDEPCKMKP
522A1     RPIQPIIASRVVNDPIVLKHECSAKGESYTIPVGTLIIPNAHSFNFDPQYHKD-PLTFNP
CYP51     HPPLIFLMRKVMT-------PMEYKG--KTIPAGHILAVSPQVGMRLPTVYKN-PDSFEP
524A1     RPPAVMVPHENI-------EDIVIGDN-VHVPKGTMILPSIWSAHFQEGGYSD-PYKFDP
556A1     YPPFPKLMPRQT-------KESDRILG-YHIPKGTMISCPVADILRDPSNFQD-PLTFKP

513F1     ERFIDNANIKEK--------------------NKNIVSFGLGLRGCIGKSFAEYMIFLTV
513G1P    ------------------------------------------------------------
513E1     ERFIETGSNNMFGGG-----------------QTNLVHFGTGVRDCVGKSLADCEIFTVL
513A1     ERFISQQQSA----------------------NSNLIHFGCGVRDCIGKSLADSEIFTML
513A2P    ERFLEELP------------------------NSNLVHFGVGVRDCMGKSLAESQIFTIL
513A3     ERFFESSQ------------------------NQGLIHFGLGVRDCVGKSLAECEIFTLI
513B1     ERWNGDEN------------------------SQTLISFGTGIRDCIGKSLAYNEIFTII
513C1     ERHIQNDVS-------------------------KSVHFAVGTRNCMGMSLSEAEVHTAM
513E2P    ------------------------------------------------------------
513E3P    ERNIESGNKFIYGCG-----------------DTNMVQFGLGNRDCIGKSLATSEIFTLL
513D1     ERFLDSTNE------------------------PKIITFGIGQRKCPGENIFEIEIYIFL
514A1     ERFKNQPLY-----------------------QKGLFHFGAGPRGCPGGRFTESFTFTFL
514A2     ERFKTQTLN-----------------------QKGLLHFGAGPRGCPGARFTECFFFTLM
514A3P    ------------------------------------------------------------
514A4     ERFKNQPLN-----------------------QKGLFHFGAGARACPGGRFTESFTFTFL
515A1     DHFLS-KDE----------------------LNIGQCAFSFGSRQCPGANVADSIMFLVS
515A2P    DRFLS-KDE----------------------SNIGQCAFSSGLRQCPGANVADSIMFLVS
515B1     LRFIENSP-------------------------PQTVTFSTGPRVCPGKNLSEDELFSFG
516A1     YRWLSSDIS---------------------QSTYSFIPFGCGSRVCVGSSLARDEIFLGI
516A2P    XXXXXXXXX---------------------XXXXSVIPCGWGSRGWGGSSLAREEILVGM
516B1     ERWLSSNHSTENGGGGGG-------VVGNSSQSEVFIPFGVGPRMCVGMGVAKDELYYCA
516B2P    ------------------------------------------------------------
508A1     SRFLKV------------------------ESNVAFLPFSIGIRSCVGQSFAQDELYICI
508A2     TRFLNS------------------------DSNPAFMPFSIGPRNCVGSNFAQDEIYIAL
508A3     SRFMNP------------------------DTNIAFLPFSIGTRNCVGQNFALDEMFLAF
508A4     SRFLQTTTTNTASNEE-----------SSFNSNLAFIPFSIGPRNCVGMQFAQDELFLAF
508C1     NRFLENSN----------------------NSMDSFFPFGLGNRVCLGRQLANDQLYLVI
555A1     DRFLNNNQ-----------------------LEKKLITFGMGPRNCLGFQFALMSIWIVN
508B1     SRFLNKNN-------------------------DAYMPFGVGDRKCVGLQLAGDEQYLSF
508B2P    KRFLNYNN--------------------------QSINF--------------DEIYIAI
508D1     NRFIGSTP-------------------------DSFMPFGTGPRNCIGQALGMDQIYLLL
508E1     NRFLDN-------------------------NIESFIPFSIGNRNCVGQQIANHELFLFV
554A1     DRFLNSK-------------------------VSDTLNFGIGPRNCIGQTIAMNQIHIFL
517A1     TRYLDES------------------------LPVPNIHFGVGQRACPGRFVAIDKMFLGI
517A4     TRYLDES------------------------LPVPNKHFGVGQRACPGRFVAIDKMFLGI
517A3P    ------------------------------------------------------------
517A2     ARYLDDS------------------------IPIPDLHFGIGQRGCPGRFVAMDQVFLCI
518A1     ERFLDQDS-----------------------HSNNYFPYGIGVRNCIGMGFSQDELYISL
518A2P    ERFIYQNN-----------------------*SNNWFPYSIGVRNCVGMGFSQDELYLLL
518B1     ERFLTDS------------------------HSNNYFPYGVGKRMCLGSNFSQHELYICL
519A1     ERWIEYKKQKDLLKEKEM-KPNSKTNSIFDDLDKVSIPYSVGNRKCPGASLSELALFSLC
519E1     ERWVEYYKNKTPTREMEATKSNITTEILPNDLDKVVLPFSIGPRNCPGNIISEINLFLAC
519B1     ERWINYKNQQQQKQQQQQ-SSESSNLEFFDDLEKVSNPFSLGPRNCVGMAIAKSSIYSVC
519D1     YRWLEYQKLKSFQNDLKQ-NNSNNKHKYYNDLDKISIPFSTGRRGCVGVQLGEAELYIVC
519C1     DRWINYYNQKQQQQQQQQQPQPIQNNNYFNDLDRVCLPFSTGPRNCVGISIAELNLFSVC
519C2P    ------------------------------------------------------------
519F1     SRWLEYKKMKDLNQFGNR-TLNGTTSKYYNDLERVSIPFGVGKRRCMAPSMADHNVLIAM
519G1     ERWVEYIKNKKVNKNGN----ENSVNKYFNDLDKISIPFGVGKRQCLSPAMAEQESLLSI
519H1P    DRWLTNDQVHLK------------------QMLNHLVPFSVGPRSCFGKNLSELEVFVVC
525A1     YRWKNIENIN---------------------NRSDFIPFSSGGRVCVGQKFSIVEARIII
521A1     ERWIENEKLRKDGKLDPTN-----------DLALISLPFSSGIRNCPGVGFAEYELFLLF
522A1     NRYIGDNPE------------------------ILHMTFDIGIRTCPFMSFAIDELFIIF
CYP51     KRFDVEDKTP-----------------------FSFIAFGGGKHGCPGENFGILQIKTIW
524A1     QRFDSVRKED-------------------VTCAKNSLVFGAGPHFCIGKELAKNQIEVFL
556A1     ERQLIFSNPKFASPSITSI--QEINGLSKRNQIIKNLPWGIGSKKCLGKELAKLIVKTII

513F1     VRLIKNYKFSNPSP-NQPLKEIGEYGLVMNCANYNAKIEKRK-------
513G1P    -------------------------------------------------
513E1     ATLINRYQFINPT--LEPLNDIGSFGIAYQPP-INNFIIKKRL------
513A1     ASLINRYEFTNPNP-STPLNEIGKFGITYSCP-ENKIIIKKRF------
513A2P    ASFINRYEFLNPNP-SIPLNDVGKFGLAFSCP-QNKIIIKKRK------
513A3     ATLLNRYQFINPNN-SKKLNDIGTFGLAQVCP-DTNIILKKRI------
513B1     ASVLNRYEFINPNP-SIPFDDNGIPGLTTQCK-NTVVQIKKR-------
513C1     AELFGNFKFTNPS--NIPLNDQGTFSVALNCP-DFFVKIERRN------
513E2P    -------------------------------------------------
513E3P    ATLINRYEF*NPKP-SIPLNDKGKLS-----------------------
513D1     VYLIKKFKFSHPIDDNLQLNDRGQFGLSLQCP-QLNIKVESR-------
514A1     VIMLKNFKIVNPTD--IPIDVEGEVGLAMQCK-PFDALFIKRN------
514A2     VLLFKNYKLQNPND--NPIDDRGDVGLSMQCK-PYDALFIKRN------
514A3P    -------------------------------------------------
514A4     VIMLKNFKIVNPTD--IPIDVEGEVGLAMQCK-PFDALFIKRN------
515A1     TKLYKTFKFERTTT--QLNDENGHFTRSLSPF-EFKSKLIIRK------
515A2P    TKLYKTFKFERTTT--QLNDENGYLTKTLCPL-EFKSKLIIRK------
515B1     TKLFKTFKFSRPNK-NQLYDEVAILGITLEPK-PFITKVSLRS------
516A1     GNILLNYIFESQNG--KPINEKGHFGIALQTV-DYNVKLTKI-------
516A2P    GNV*LNYIWESQKG--KPIKEKGHLGSALQTG-DYNVKVTKI-------
516B1     SQMFMNFKWSPVND--KPIDDEGVARIALEYK-EYQVVLERRK------
516B2P    -------------------------------------------------
508A1     SNILLNFKLKSIDG--KKIDETEEYGLTLKTKNRFNVTLEKRII-----
508A2     SNMILNFKFKSIDG--KPVDETQTYGLTLKPN-PFKVILEKRK------
508A3     SNIILNFKFSSIDG--KQIDETELYGVTLRCKNKFNVSIKKRI------
508A4     ANIVLNFTIKSVDG--KKIDETISYGVTLKPKTRFKVLLEKRLI-----
508C1     ANLILKYKLKTIDE--NKINEDGIFGLTVSPN-KYKINLESR-------
555A1     LILFKSIKFSSNKL---IEEEIREGGTTLSPF-PFKINLIKR-------
508B1     SNILLNFNLKNI-G--TPVSDYEEFGLTLKPN-KFKVLLESRK------
508B2P    SNILLNFKIT-------AVKNHYNFNVFDDNL-QSSVLIEKR-------
508D1     SNIFLNFKITSENG-KKLDDTDYVSGLNLKPA-KYKVCLEKR-------
508E1     SNFILNYKITPITN--EPIDTTENFGINIRPN-SFKINVYKRN------
554A1     SNLILNYRMFSIDC--LPLPENLILSVSVRPT-EYSLKLIKRV------
517A1     SNLLLKYKLKSQNG--EKIDDTIHFSVSLKAK-DYGIKLEKRI------
517A4     SNLLLKYKLKTQNG--EKIDDSIQFSVSLKAK-DYGIKLEKRI------
517A3P    -------------------------------------------------
517A2     ANTLLKYKIKSIDG--KKIDDTIQFSVYLKPK-DFGILLEKRNKLFVND
518A1     SNLVLNFKLLPLIE-NSKICDKPIFGFSFKPN-EFKINLEKRNN-----
518A2P    TNLVLNFHILPPFE-NTKIDGTPIFGFSFKPK-LR--------------
518B1     TNIVLNFKIKSIDG--KPLNEIPNYGITFRPN-IFEVKLENR-------
519A1     SNILLNFELKSIDG--KPIDDTEVYGLTIHTK-VHPISLTLRP------
519E1     SNILLNFEFSNG-G--KKIDETEVFGITIHPK-DFSIQLKKRE------
519B1     SNILLNFELSSINN--QIIDDNEVFGVSINPK-EFSIKLTKR-------
519D1     ANLVYNFKIESWDG--KKINELEDFGIIIHPS-SHNLKITKRNNK----
519C1     ANIILNFQIKSIDG--MQLKDIEVSGISIHPI-PFSIKLISRN------
519C2P    -------------------------------------------------
519F1     ANIVLNFTMKSSDP--KQMPLSEEEQYAITIKPKYPFKVLFEKRS----
519G1     ATVVLNYKLKS-NG--QKKLNEKEVYSITIKPQPFKLFLEKRV------
519H1P    SNILLNFELSSYNG-----KPVDDFEIFGIHPPEFPVKLIKRK------
525A1     SKLILNFELSFNNL--KSKPFKIYQRATLPPKYPVFLNFKKRENN----
521A1     SNIILNFHLSSPNN--LKLNESGHFGLTMKPF-PFLVDLN---------
522A1     SRLFQSFEFQPIDN--TPISEEAFTINSIRPK-QWSCQVIERDHK----
CYP51     TVLSTKYNLEVGPV-----PPTDFTSLVAGPKGPCMVKYSKKQK-----
524A1     TKLAMSTEWTHNKT---PGGDEIIFGPTIFPKDGCNITIKARN------
556A1     VILYSQYTFDKHLD----ENDEELCDTNNQPKIQITFNPEIKPPLLLK-