172 sequences intron locations are coded phase 00, phase 1, phase 2

12a4m           ------------------------------------------------MLKVRSALSLIQ 12

12a5m           ------------------------------------------------MLKGRIALNILQ 12

12A4ps          ------------------------------------------------MLKVRTGLSIIQ 12

12A5ps          ------------------------------------------------MLKVRSGLSIIQ 12

12c1m           ------------------------------------------------MLRLTV-KHGLR 11

12c1ps          ------------------------------------------------MIRRAVVQQGIR 12

12e1m           --------------------------------------------------MLSTQWNANK 10

12e1ps          --------------------------------------------------MLSQQLNAKR 10

12d1m           -------------------------------------------------MNTLSSARSVA 11

12d1ps          ------------------------------------------------MNAWQSLTRRLA 12

12b2m           ---------------------------------------MWKYSNKIIYRNVSGNQLWFN 21

12B2ps          ---------------------------------------MWKNTMKTVRRQSAAHQLFNA 21

49A1m           MSGLRKTSIALMRRSTSS----TTILPHSG---GVGGAVSPPSSGVGVATEIEKSIAMQR 53

49A1ps          MSGLRKTSFALMRRSTYSGSATATMLPHAGPGPGTGVDGAAPPSGVGVATEIEKSIARQR 60

301a1m          ---MNNLSLKAWRSTVSC----G----------PNLRQCVPRISGAGSR-----RAQCRE 38

301A1ps         ------MNKLPVRACTAS----A----------SSLRRTVSRISGSGLLPNEKQRLEIRD 40

302a1m          ------------------------------------------------------------

302A1ps         ------------------------------------------------------------

314a1m          ------------------------------------MAVILLLALALVLGCYCALHRHKL 24

314a1ps         ------------------------------------MAVILLLALALVLGCYCAIHRHKI 24

315a1m          ----------------------------------------------MTEKRERPGPLRWL 14

315a1ps         ------------------------------------------------MNRKRTSLLHWL 12

6a2m            -----------------------------------------------------------M 1

6a2ps           -----------------------------------------------------------M 1

6a8m            --------------------------------------------------------MALT 4

6a18m           --------------------------------------------------------MQLT 4

6a8ps           --------------------------------------------------------MGVT 4

6a9m            --------------------------------------------------------MGVY 4

6a21m           --------------------------------------------------------MSVG 4

6a21ps          ------------------------------------------------------MAVGVG 6

6a17m           ------------------------------------------------------------

6a23m           -----------------------------------------------------------M 1

6A17ps          -----------------------------------------------------------M 1

6A23ps          -----------------------------------------------------------M 1

6a20ps          -----------------------------------------------------------M 1

6a20m           -----------------------------------------------------------M 1

6a19m           -----------------------------------------------------------M 1

6a22m           -----------------------------------------------------------M 1

6A22ps          -----------------------------------------------------------M 1

6a13m           -----------------------------------------------------------M 1

6A13ps          -----------------------------------------------------------M 1

6a14m           -----------------------------------------------------------M 1

6A14ps          ------------------------------------------------------------

6a15pm          ------------------------------------------------------------

6a16m           -----------------------------------------------------------M 1

6A16ps          -----------------------------------------------------------M 1

6u1m            -----------------------------------------------------------M 1

6u1ps           --------------------------------------------------------MDLL 4

317a1m          -------------------------------------------------------MWIIF 5

317a1ps         -------------------------------------------------------MWIIF 5

6g1m            ------------------------------------------------------------

6G1ps           ------------------------------------------------------------

6w1m            ------------------------------------------------------------

6w1ps           ------------------------------------------------------------

6v1m            -----------------------------------------------------------M 1

6v1ps           -----------------------------------------------------------M 1

6g2m            ------------------------------------------------------------

6g2ps           ------------------------------------------------------------

6t1m            ------------------------------------------------MIAVFSLIAAAL 12

6t2pm           -----------------------------------------------MVIAFFIFLCAAL 13

6t1ps           -------------------------------------------MILVIGVLFIAATVAAI 17

6t3m            -----------------------------------------------------------M 1

6t3ps           -----------------------------------------------------------M 1

9b1m            ----------------------------------------------------------MS 2

9b2m            ----------------------------------------------------------MA 2

9B2ps           ----------------------------------------------------------MV 2

9f2m            -----------------------------------------------------------M 1

9f3pm           -----------------------------------------------------------M 1

9F2ps           -----------------------------------------------------------M 1

9c1m            ----------------------------------------------------------MV 2

9c1ps           ----------------------------------------------------------MA 2

9h1m            ---------------------------------------------------------MDQ 3

9h1ps           ---------------------------------------------------------MEK 3

6d2m            ------------------------------------------------------------

6d2ps           -----------------------------------------------------------M 1

6d4m            -----------------------------------------------------------M 1

6d4ps           -----------------------------------------------------------M 1

6d5m            ------------------------------------------------------------

6D5ps           ------------------------------------------------------------

310a1m          ------------------------------------------------------------

310a1ps         ------------------------------------------------------------

28a5m           ----------------------------------------------------------MV 2

28A5ps          ----------------------------------------------------------MI 2

28d1m           --------------------------------------------------------MCPI 4

28d1ps          --------------------------------------------------------MCPI 4

28d2m           --------------------------------------------------------MCPV 4

28c1m           ----------------------------------------------------------MF 2

28c1ps          ----------------------------------------------------------MI 2

309a1m          -------------------------------------------------------MFTLV 5

309a1ps         -------------------------------------------------------MWTTV 5

309a2m          -------------------------------------------------------MYILA 5

309a2ps         -------------------------------------------------------MYILV 5

308a1m          ------------------------------------------------------------

308a1ps         -------------------------------------------------------MLLLL 5

4aa1m           -------------------------------------------MHLRLLSPPQLERTTNL 17

4aa1ps          ------------------------------------------MQFYTRMTVPQLERATRT 28

4C3m            ---------------------------------MSSKVITSLMAESILLSKVGQVISGYS 27

4C3ps           ---------------------------------MSSKVISSLMAESILLTKMAQVISGYS 27

4d1m            ---------------------------------------------------------MFL 3

4D1ps           ---------------------------------------------------------MFL 3

4d1malt         ---------------------------------------------------------MWL 3

4D1psalt        ---------------------------------------------------------MWL 3

4s3m            --------------------------------------------------------MSTL 4

4s3ps           --------------------------------------------------------MNTW 4

312a1m          ---------------------------------------------------------MFW 3

312a1ps         --------------------------------------------------------MVVW 4

4g1m            ----------------------------------MAVEVVQETLQQAASSSSTTVLGFSP 26

4G1ps           ----------------------------------MTVDTVQETLQHAATS--TSGLGFSP 24

4g15m           ------------------------------------MEVLKKDAALGSPS--S------- 15

4G15ps          ------------------------------------MEVLKKDAAMGSPS--S------- 15

4d2m            ------------------------------------------------------MLGVVG 6

4D2ps           --------------------------------------------------------MLAL 4

4d14m           ---------------------------------------------------------MYL 3

4d14ps          ---------------------------------------------------------MFV 3

4d8m            ----------------------------------------------------------ML 2

4d8ps           ----------------------------------------------------------ML 2

4ae1m           --------------------------------------------------------MLVV 4

4AE1ps          --------------------------------------------------------MLMA 4

4d20m           ---------------------------------------------------------MWL 3

4D20ps          --------------------------------------------------------MLLL 4

4d21m           ---------------------------------------------------------MWI 3

4e2m            -------------------------------------------------------MWFVL 5

4e2ps           -------------------------------------------------------MWFVL 5

4e1m            -------------------------------------------------------MWIVL 5

4e1ps           -------------------------------------------------------MWFAL 5

4e3m            -------------------------------------------------------MWLAV 5

4e3ps           -------------------------------------------------------MWLAV 5

4ad1m           -------------------------------------------------------MFLIA 5

4AD1ps          -------------------------------------------------------MFLIA 5

4p1m            -------------------------------------------------MIILWLILALS 11

4p3m            -------------------------------------------------MLILWLVGAFI 11

4p1ps           -------------------------------------------------MIVFLLTVALC 11

4P2ps           -----------------------------------------------TMIVVLWLTVALC 13

4P3ps           -------------------------------------------------MITLWLTVALC 11

4p2m            -----------------------------------------------MMICLLWISVAIL 13

4ac1m           ------------------------------------------------MWIALLGIPILL 12

4AC1ps          ------------------------------------------------MLIALLGTPLLL 12

4ac2ps          ------------------------------------------------MFELLLGVPLIV 12

4ac2m           -----------------------------------------------MFLEVLFAAPLVI 13

4ac3m           ------------------------------------------------MWIALLGSSLLI 12

311a1m          -----------------------------------------------------------M 1

311a1ps         ------------------------------------------------------------

316a1m          ---------------------------------------------------------MIL 3

316A1ps         ---------------------------------------------------------MIL 3

313a2m          ----------------------------------------------------------MI 2

313a3m          ----------------------------------------------------------MD 2

313a1m          ----------------------------------------------------------ML 2

313C1ps         ----------------------------------------------------------MY 2

313C2ps         ----------------------------------------------------------MI 2

313a5m          ----------------------------------------------------------ML 2

313a4m          ----------------------------------------------------------ML 2

313a4ps         ----------------------------------------------------------ML 2

313A4bps        ----------------------------------------------------------ML 2

313b1m          ----------------------------------------------------------ML 2

313b1ps         --------------------------------------------------------MLLG 4

318a1m          ----------------------------------------------------------MH 2

318A1ps         ----------------------------------------------------------MH 2

18a1m           -------------------------------MLADSYLIKFVLRQLQVQQ-DGDAQHLLM 28

18a1ps          -------------------------------MLADSYLIKFLLRQLQVQQQDAGAQHLLM 29

306A1m          -------------------------------------MSADIVDIGHTGWMPSVQSLSIL 23

306A1ps         --------------------------------MSASFATASASASVFDWLPLSGHSFCLL 28

303a1m          ----------------------------------------------------------MF 2

303A1ps         ----------------------------------------------------------MF 2

305a1m          --------------------------------------------------------MSAL 4

305A1ps         --------------------------------------------------------MSAL 4

304a1m          --------------------------------------------------------MITE 4

304a1ps         --------------------------------------------------------MLTE 4

307a1m          -------------------------------------MLAALIYTILAILLSVLATSYIC 23

307a1ps         ---------------------------------------MSAVYSVLAILLAIIITSYIR 21

307a2pm         -------------------------------------MLTSVFYVLFAIAITIILISYVF 23

307a2pps        -------------------------------------MFFSVCYLIIAIGITAIVISYIL 23

 

                           2A 2B                    2C 2D          2E

12a4m           SQKATLSLATQKR----WQTNVATAEARE--------DSEWLQAKPFEQIPRLN---MWA 57

12a5m           SQKPIVFSASQQR----WQTNVPTAEIRN--------DPEWLQAKPFEEIPKAN---ILS 57

12A4ps          AQKAALSVSCPLR----WQTTAAVAEPRN--------DEEWLQARPFKQIPST----TFL 56

12A5ps          AQKAALSVSSPLR----WQTTAAVAEPRN--------DEEWLQARPFEQIPST----TFL 56

12c1m           ANSQLAATRNPD---------ASSYVQQL--------ESEWEGAKPFTELPGP----TRW 50

12c1ps          ARSSLAEVQVISKKNLDPAAASSSYMEQL--------EGEWSTAKPFEEIPGP----TRW 60

12e1m           QISRQIYQLCR--------------------------VLNLEEAKPYADIPGP----SKL 40

12e1ps          QASCQIYQIYRNE------------------------TISLEQAKPYAEVPGP----SKF 42

12d1m           IYVGPVRSSRSAS--------VLAHEQAK--------SSITEEHKTYDEIPRP----NKF 51

12d1ps          VATGPIRSLRGSS--------AQAQAQRS---------VEDVEARPFSEVPRP----GRL 51

12b2m           RNSSVGGTLSQQT----QLELADS---RI--------DEKWQQARSFGEIPGP----SLL 62

12B2ps          RDLSLNRTLGQQT----HLELLDKSPPRT--------DERWQQAKSYGELPGP----NGW 65

49A1m           LRTGESSNPKKLNVSQQPVTSVATTRTTASSLPAETTSSPAAAVRPYSEVPGPYPLPLIG 113

49A1ps          LRQGQSETAKKLNVSHLAATAVPATETAT--ATATRTASPTAGVRPYSEVPGPYPLPLIG 118

301a1m          SSTGVATCPHLADSEEASAP---RIHSTS----------EWQNALPYNQIPGPKPIPILG 85

301A1ps         SSTGVAACPHLLEPEETAAPTTPRIHSTP----------EWQNALPYNQIPGPKPLPILG 90

302a1m          ---MLTKLLK------------ISCTSRQC-----------TFAKPYQAIPGPRGPFGMG 34

302A1ps         ---MLTKLLK------------ISCTSRQC-----------TFAKPFEAMPGPRGPWGLG 34

314a1m          ADIYLRPLLKNTLLEDFYHAELIQPEAPK------------RRRRGIWDIPGPKRIPFLG 72

314a1ps         GATYLKPLLKNTPLEDCYHATPVVPEQQKS-----------RRRRSIWDIPGPQRIPFLG 73

315a1m          RHLLDQLLVRILSLSLFRSRCDPPPLQRFP-------ATELPPAVAAKYVPIPR-VKGLP 66

315a1ps         QQLLRTLLVRLLCQFKSKAGLTKATAG-----------SNRCRSKGGEIVPIPR-VKGLP 60

6a2m            FVLIYLLIAISS---------LLAYLYHRN---------FNYWNRRGVPHDAP--HPLYG 41

6a2ps           LILIYLVIAVGS---------LVAYLLHRN---------FQYWKRKGVPHDPP--HPFYG 41

6a8m            YILFQVAVALLA---------ILTYYIHRK---------LTYFKRRGIPFVAP--HLIRG 44

6a18m           YFLFQVAVALLA---------IVTYILHRK---------LTYFKRRGIPYDKP--HPLRG 44

6a8ps           YVLLQVAVALLA---------IVTYYVYRR---------LSYFKSRGIPHDTP--HLILG 44

6a9m            SVLLAIVVVLVG---------YLLLKWRRA---------LHYWQNLDIPCEEP--HILMG 44

6a21m           TVLLTALLALVG---------YLLMKWRST---------MRHWQDLGIPCEEP--HILMG 44

6a21ps          ALLLWTLVALVV---------YLLLKWLLG---------RQYWQNLGIPCEEP--HWLLG 46

6a17m           MLLLALIVVILS---------LLVFAARRR---------HGYWQRRGIPHDEV--HPLFG 40

6a23m           SLLLTLIALLVS---------LLLFMARRR---------HGYWQRRGIPHDVP--HPIYG 41

6A17ps          SLVLALIAIVVS---------LVLFAARRR---------HGYWQRRGIPHDVP--HPLFG 41

6A23ps          SLVLALIAIVVS---------LVLFAARRR---------HEYWQNLGIPCEEP--HWLLG 41

6a20ps          AIIIVLLVGVIS---------LAVWWVHQN---------FSYWKRRGIPHDPP--NIPKG 41

6a20m           AVMIVLLIGVIT---------FVAWYVHQH---------FNYWKRRGIPHDEP--KIPYG 41

6a19m           AILLGLVVGVLT---------LVAWWVLQN---------YTYWKRRGIPHDPP--NIPLG 41

6a22m           LDVVALLLIALA---------VGFWFVRTR---------YSYWTRRGIGSEPA--RFPVG 41

6A22ps          LDVIALLLITLA---------IGFWYVRTR---------LSYWARRGIGHVRP--TFPMG 41

6a13m           LTLLVLVFTVGL---------LLYVKLRWH---------YSYWSRRGVAGERP--VYFRG 41

6A13ps          WTLLALVLVAGA---------LIYSRLLEH---------YDYWRRKGVAGEKP--VLFLG 41

6a14m           LFTIALVGVVLG---------LAYSLHIKI---------FSYWKRKGVPHETP--LPIVG 41

6A14ps          --------MALA---------LAYNFYRNT---------YSYWERKGVPNERP--LPLIG 32

6a15pm          ------------------------------------------------------------

6a16m           DFTLLLLTSLLS---------FLLGYLRYR---------FTYWELRGIPQLRP--HFLFG 41

6A16ps          GFVLILLTSLLS---------GVLGYLRCK---------YNYWQINGVKQLRA--HFLFG 41

6u1m            HRTLLTALGALS---------VVYALVKFS---------LGYWKRRGILHEKP--KFLWG 41

6u1ps           HRALLTAVGALS---------LFYALVKVS---------LGYWKRRGILHEKP--KFFWG 44

317a1m          LIIGLLVLGLLV---------LLIIAARYQ---------RDYWRYLDIPHERP--KKLWP 45

317a1ps         TIIGLVVLGLVI---------LLIMAARYQ---------RDYWHYLNIPHERP--KKLWP 45

6g1m            MVLTEVLFVVVA------ALVALYTWFQRN---------HSYWQRKGIPYIPP--TPIIG 43

6G1ps           MALTEALFLIVG------ALSAVYIWFQRN---------HSYWQRKGIPYIPP--TPIIG 43

6w1m            ---MLLLLLLGS------LTIVFYIWQRRT---------LSFWERHGVKYIRP--FPVVG 40

6w1ps           -MSTELLFLIAT------VAIVFYVWHKRR---------HSFWKRHGVKEIGP--LPILG 42

6v1m            VYSTNILLAIVT------ILTGVFIWSRRT---------YVYWQRRRVKFVQP--THLLG 44

6v1ps           VYSTNILLAIVT------ILTAVFVWSRRT---------YVYWQRRRVKFVQP--AHLLG 44

6g2m            -MELVLLILVAS------LIGIAFLALQQH---------YSYWRRMGVREIRP--KWIVG 42

6g2ps           -MVLGLFLLVVI------FLATICFLLQQH---------YAYWRRRGVRELRP--HWILG 42

6t1m            AVGSLVLLPVVLRGGCLLVVTIVWLWQILH---------FWHWRRLGVPFVP--AAPFVG 61

6t2pm           AVGSVVLLPLIA-------LLAVWLWQRRH---------FRIWRRLGVPYLP--AAPVLG 55

6t1ps           GLLFFVVFPLVCAAG-LIIFGIIWLWQRHH---------FCHWLRLGVPYIR--ATPFVG 65

6t3m            LLIWLLLLTIVT----------LNFWLRHK---------YDYFRSRGIPHLPPSSWSPMG 42

6t3ps           VSLWLLMLGILS----------IYLWLRQR---------YSYFERHNIVHLPVSAWTPLG 42

9b1m            FVEICLVLATIG--------LLLFKWSTGT---------FKAFEGRNLYFEKP--YPFLG 43

9b2m            LIEICLALVVIG--------YLIYKWSTAT---------FKTFEERKLYFEKP--YPFVG 43

9B2ps           CLEICLAILVLG--------FMIYKWSTAT---------HRAFDERGVYFEEP--KPFFG 43

9f2m            LWEFFALFAIAA--------ALFYRWASAN---------NDFFKDRGIAYEKP--VLYFG 42

9f3pm           LWEFLALFAIAT--------ALFYRWASAN---------NDFFKDRGIAYEKP--VLYLG 42

9F2ps           LLEFVALLGIAF--------ALFYRWATAN---------NEFFKEKGIPFAKP--KLYFG 42

9c1m            FVELSIFVAFIG--------LLLYKWSVYT---------FGYFSKRGVAHEKP--IPLLG 43

9c1ps           FEVLLALGALIG--------FLLYKWAEPP---------VRFFLKRGVVHEAP--VPLLG 43

9h1m            SMIALALFIILL--------VLLYKWSVAK---------YDVFSERGVSHEKP--WPLIG 44

9h1ps           WIVVLSLVAVLL--------VLLYKWSVAK---------YGILTERGVPHAQP--KPLLG 44

6d2m            MWTILLTILIAG---------LLYRYVKRH---------YTHWQRLGVDEEP--AKIPFG 40

6d2ps           WAILTLLTLALG---------LLYQFVRRH---------YSSWQRLGVDEET--PKIPMG 41

6d4m            FSLILLAVTLLT---------LAWFYLKRH---------YEYWERRGFPFEKH-SGIPFG 42

6d4ps           FSLIVLAGTLLA---------LGWFYLKHH---------YQYWERRGFPFDRQ-STIPFG 42

6d5m            MIGIYLLIAAVT---------LLYVYLKWT---------FSYWDRKGFPSTG--VSIPFG 40

6D5ps           MIGILLLVAAVS---------LLYVYLKWT---------FSYWDRQGFPSAG--VTIPFG 40

310a1m          -MWLLLPILLYS---------AVFLSVRHI---------YSHWRRRGFPSEK--AGITWS 39

310a1ps         -MWLLLPILLYS---------VLFLAVRHI---------YSHWRRKGFPSER--AGISWS 39

28a5m           LITLTLVSLVVG---------LLYAVLVWN---------YDYWRKRGVPGPKP--KLLCG 42

28A5ps          LITLALGLATVG---------LLYLLMTWN---------FDHWRKRRVPGPKP--KIPTG 42

28d1m           STALFVIAAILA---------LIYVFLTWN---------FSYWKKRGIPTAKS--WPFVG 44

28d1ps          CAVLLLLATLLT---------LIYIFLTWN---------FGYWKRRGIQTAKA--WPLVG 44

28d2m           TTFLVLVLTLLV---------LVYVFLTWN---------FNYWRKRGIKTAPT--WPFVG 44

28c1m           GSLLLGIATLLG---------AIYAFLVSN---------FGHWRRRGVTEPRA--LPLFG 42

28c1ps          GSLLLAVGALAT---------LVYGFLVWN---------FGHWRARGIKEPRA--LPLLG 42

309a1m          GLCLTIVHVAFA---------VVYFYLTWY---------HKYWDKRGVVTAEP--LTILG 45

309a1ps         GLLLGAVHVAFA---------AVYLYLTWH---------HKYWQKRGVLTAEP--LTILG 45

309a2m          SLALILLHLLVL---------PIYLYLTWH---------HKYWRKRGLVTARP--LTLLG 45

309a2ps         TLGLIVVHLLLL---------PLYVYLTWH---------HRFWRKRGLVTARP--LTMLG 45

308a1m          -MLPLVLFILLA---------ATLLFWKWQ---------GNHWRRLGLEAPFG--WPLVG 39

308a1ps         LLLLLLLLFFLG---------TLWRRLAWS---------NSHWRRRVVSGPQG--CPLVG 45

4aa1m           ELCSILILLVISLS------IYTFYATLNT---------YLRSVLLSLRLTGPPSLPFLG 62

4aa1ps          ELCSILALLVISLS------IYLFYAHLDT---------YLRSVILSLRLSGPPTLPILG 73

4C3m            PITVFLLGSILIFL------VVYNKRRSR-------------LVKYIEKIPGPAAMPFLG 68

4C3ps           PITIFLLASIALFL------VVYNKRRSR-------------LVKHIEKIPGPAAMPFLG 68

4d1m            VIGAILASALFVGL------LLYHLKFKR-------------LIDLISYMPGPPVLPLVG 44

4D1ps           LLGALLASGLFVAL------LVYQLKFKR-------------VIEVISYMPGPPVLPLVG 44

4d1malt         LLSLVLLLAIIALE------MRRFLRNMR-------------------TIPGPLPLPLLG 38

4D1psalt        SLVFGAVGTVLVLG------LFSWLPFCRR---------RRRISELAELLPGPKPWPLLG 48

4s3m            ALVAFVLWAAFLRY------LPKILNFLR-------------LQRFAKTLPGPTIGELIA 45

4s3ps           ALMAFALWALFLRY------LPQILTFLR-------------LQRFAKTLPGPSVSELIA 45

312a1m          LGFGLLLLALSLYL------LYVFERQSR-------------IDRLTHKWPAPPALPFIG 44

312a1ps         LGLCLLLIVLSLYL------LYAFERQTR-------------IDRLTHNWPAPPSLPILG 45

4g1m            MLTTLVGTLVAMAL------YEYWRRNSR-------------EYRMVANIPSPPELPILG 67

4G1ps           MLTTLVGTIVALGL------YEYWRRNTR-------------EYRMVANIPSPPGLPLLG 65

4g15m           VFYFLLLPTLVLWY------IYWRLSRAH-------------LYRLAGRLPGPRGLPIVG 56

4G15ps          VFYFLLLPTLVLWY------IYWRLSRAH-------------LYRLAGRLPGPRGLPIVG 56

4d2m            VLLLVAFATLLLWD------FLWRRRGN-------------------GILPGPRPLPFLG 41

4D2ps           VVFLVALTTVLVWD------YFWRKRRND--------------IL--HYMPGPRGLPLVG 42

4d14m           ELFAILLATALAWD------YMRKRRHNK--------------MYAEAGIRGPKSYPLVG 43

4d14ps          ELLVLLLTVALVWD------YLVGRKHKR--------------LFDRAGITGPKAWPLVG 43

4d8m            LFLLVVLLFGAGWI------IHLGQADRR--------------RK-VANLPGPICPPLIG 41

4d8ps           LLVLVLLLVAVGWL------VHRGQAERR--------------RA-VSNLPGPMCPPLLG 41

4ae1m           LLVALLVTRLVASL------FRLALKELR--------------HPLQGVVPSVSRVPLLG 44

4AE1ps          LLLTMALTLIVAWL------LQLALREMR--------------HPLRGFVPSVSRVPLVG 44

4d20m           TLITGALILLLTWD------FGRKRQRVL--------------AFEKSAIPGPISIPILG 43

4D20ps          TLAFGALAVLLTWD------FVRKRQRAA--------------TLERSKISGPLSLPVLG 44

4d21m           LLGIAVLIMTLVWD------NSRKQWRVN--------------TFEKSRILGPFTIPIVG 43

4e2m            YIFLALPLLLVAYL------ELS--TFRR--------------RRVLNKFNGPRGLPLMG 43

4e2ps           YLFLALPLLLVAYL------ELS--TFRR--------------RRALNKFKGPSRLPIVG 43

4e1m            CAFLALPLFLVTYF------ELG--LLRR--------------KRMLNKFQGPSMLPLVG 43

4e1ps           YLVLALPLLWLAYL------ELK--SLRR--------------RRVLNKFKGPKVLPVVG 43

4e3m            LALLVLPLITLVYF------ERK--ASQR--------------RQLLKEFNGPTPVPILG 43

4e3ps           LALLALPLLVLVYF------ELR--ASRR--------------RRMLKVFNGPAPVPVLG 43

4ad1m           IAIILATILVFKGV------RIFNYIDHM--------------AGIMEMIPGPTPYPFVG 45

4AD1ps          IAIILATILVFKGV------KIFNYIDHM--------------AGIMEMIPGPTPYPFVG 45

4p1m            ALLYWLHRANKDYH------ILSFFTKRIR---------LKDGTPVEIIAPIAKGKTIFG 56

4p3m            VLIQWIYRLNRDYC------ILGFFAKRIR---------TKNGQNPESIAPLVKGSTIFA 56

4p1ps           ALVLWLYRINKDYY------ILAFFSRRVR---------TKDGRPVESILPSPKGRTIFA 56

4P2ps           VIVHWLYRVNKDYY------IMAFFSRRVR---------TKDGRPVESIVPMIKGRTVFA 58

4P3ps           VVIHWLYQVNKDYY------ILAFFSRRVY---------TRDDRPVESLVPSPKGRTIFA 56

4p2m            VVIHWIYKVNKDYN------ILAFFARRVQ---------TKDGKPLDSLVPMIKGRTVFA 58

4ac1m           AVLTLLLKHINKTY------FILSLTKRVR---------TEDGSPLESKVAIMPGKTRFG 57

4AC1ps          LGVWLLLQRLNRTY------FILSLTRRVR---------TEDGSPLESKVAVMPGTTRFG 57

4ac2ps          LLCCVLLRRLNRKY------FVLSLCKRLQ---------AEDGSPLESKIAVMPGRTRFG 57

4ac2m           FIFRKLWAHLNRTY------FILSLCKRIR---------TEDGSLLESKIYVAPSKTRFG 58

4ac3m           GALWLLLRQLNKTY------FILSLCKRVR---------TADGSPLESKVFVVPGKTRFG 57

311a1m          ALWPLLLITLTIWI------LVRKWTLLR----------------LGSSLPGPWAFPLLG 39

311a1ps         ------------------------------------------------------------

316a1m          TATFICFCLASAFN------YFRARRQRS----------------LIKNLKGPFTWPLMG 41

316A1ps         TTTFLCFCVASAIN------YFRTRRQRS----------------LIKNLGGPFSWPLMG 41

313a2m          VIQLLIAASLILWI------RFLWSRRKLY---------MLMMQLP-----GRMGLPLLG 42

313a3m          TFQLLLAVGVCFWI------YFLWSRRRLY---------MMHFKIP-----GPMGLPILG 42

313a1m          TINLLLAVGALFWI------YFLWSRRRLY---------FLMLKIP-----GPIGLPILG 42

313C1ps         SLHLWIAVGILAWI------YFLWSRRRFY---------LLMLRVK-----GPVGYPFLG 42

313C2ps         TLQLWIAVGILAWI------YFLWSRRRFY---------LLMLRVK-----GPVGYPFLG 42

313a5m          TLQIFEAFAIILCV------YFLWSRRRFY---------IMMLKLP-----GPMGFPFIG 42

313a4m          TWTLWCGLLFLLWI------YFLWSRRRFY---------LLTLKIP-----GPLGYPILG 42

313a4ps         TWTLWCGLLFVLWI------YFLWSRRRFY---------LLTLKIP-----GPIGYPLLG 42

313A4bps        TWSLWCGLLFVLWI------YFLWSRRRFY---------LLTLKIP-----GPIGYPFLG 42

313b1m          ASIILSGWLLLAWL------YFLWSRRRYY---------KVAWQLR-----GPIGWPLIG 42

313b1ps         TCIILAIWLLLVWT------YFLWTRRRYY---------KAAWQLK-----GPIGWPLIG 44

318a1m          LNIALWACGALLAV------LLAWQQRKCW---------RLIWQLNG--WRGVIQQPVLW 45

318A1ps         LYVALWVCGTALAL------LLGWQQRKCW---------RLIWQLNG--WRGVAQQPILW 45

18a1m           VFLGLLALVTLLQW-------LVRNYRELR-----------------KLPPGPWGLPVIG 64

18a1ps          VFLGFLALVSLLQW-------MLRHYRELR-----------------KLPPGPWGLPVIG 65

306A1m          LVPGALVLVILYLC-------ERQCNDLMG-----------------APPPGPWGLPFLG 59

306A1ps         VVPGLLILIILWLC-------DHQYDRVLG-----------------RPPPGPWGLPWLG 64

303a1m          YTVIWIFCATLLAI-------LFGGVRKPK-----------------RFPPGPAWYPIVG 38

303A1ps         YAVIWIFFATLLAV-------LLGGVRKPK-----------------RFPPGPRWYPIVG 38

305a1m          IFLCAILIGFVIYS-------LISSARRPK-----------------NFPPGPRFVPWLG 40

305A1ps         IFLCAILIGFVIYS-------LIKSVQRPK-----------------NFPPGPRFLPWLG 40

304a1m          TLLTICAAVFLCLS-------YRYAVGRPS-----------------GFPPGPPKIPLFG 40

304a1ps         LLLTICSAAFLYLS-------YRYAVGRPV-----------------GFPPGPPRIPFFG 40

307a1m          IIYGVKRRVLQPVK-------TKNSTEINHN-----------AYQKYTQAPGPRPWPIIG 65

307a1ps         ILYKSRRRVCVAIR-------NGKSSTESE--------------QIYEQAPGPRPWPIIG 60

307a2pm         LLLKCKQKAFVVIG-------LLYQEKKYQ---------------CFDQAPGPHPWPIIG 61

307a2pps        IIFKCNEKATVRIG-------LSNPEKAIR---------------KFGQAPGPQPWPIIG 61

 

                   3A            3D  3F 3G

                   3B    3C      3E     3H      3I         3J

12a4m           LSMKMSMPGGK--YKNMELMEMFEAMRQDYG----------DIFFMPGIMGNPPFLSTHN 105

12a5m           LFAKSALPGGK--YKNLEMMEMIDALRQDYG----------NIIFLPGMMGRDGLVMTHN 105

12A4ps          STVRNFMPGGK--YRKLDIVELFQALQDDYG----------DIFYLPGIMGGPSFLTTHN 104

12A5ps          STVRNFMPGGK--YSKLDIVNLFKALQDDYG----------NILYLPGMMGGTSYLMTHN 104

12c1m           QLFRGFQKGGE--YHQLGMDDVMRLYKKQFG----------DICLIPGLFGMPSTVFTFN 98

12c1ps          QLWRGFQKGGE--FHHLDMAELMDLYRSRFG----------DMVRVPGLFGMPTTVFTFK 108

12e1m           QLIRAFLPGGL--YKNLPVHEMFLDMNRQYG----------SIFRMPSVAG-TDLVLTMN 87

12e1ps          QMIRAFMPGGR--YKNAPAHEMFLDLSRQFG----------GLFRMPSIAG-TDMVLTMN 89

12d1m           KFMRAFMPGGE--FQNASITEYTSAMRKRYG----------DIYVMPGMFGRKDWVTTFN 99

12d1ps          QFMRSFMPGGE--FSDASIVEFSMGMRRRYG----------DIFILPGMFGRKDWVVTFN 99

12b2m           RMLSFFMPGGA--LRNTNLIQMNRLMREMYG----------DIYCIPGMMGKPNAVFTYN 110

12B2ps          RMISYFLPGGK--LHNTNLIQMNRRLRVMYG----------DIYRLPGLMGKPDIVFTYN 113

49A1m           NSWRFAPLIGT--YKISDLDKVMNELHVNYG----------KMAKVGGLIGHPDLLFVFD 161

49A1ps          NSWRFAPLIGT--YKISELDKVMNELHVNYG----------KMAKVGGLIGHPDLLFVFD 166

301a1m          NTWRLMPIIGQ--YTISDVAKISSLLHDRYG----------RIVRFGGLIGRPDLLFIYD 133

301A1ps         NTWRLMPIIGQ--YTISDVANISSLLHDRYG----------RIVRFGGLIGRPDLLFIYD 138

302a1m          NLYNYLPGIGS--YSWLRLHQAGQDKYEKYG----------AIVRETIVPG-QDIVWLYD 81

302A1ps         NLYNYMPIIGS--YSFLRLHQAGQDKYERYG----------AIVRETMAPG-QDIVWLYD 81

314a1m          TKWIFLLFFRR--YKMTKLHEVYADLNRQYG----------DIVLEVMPSN-VPIVHLYN 119

314a1ps         TKWIFFVFFRR--YKMTKLHEVYADLNRRYG----------DIVLEVMPSN-VPIVHLYK 120

315a1m          VVGTLVDLIAA--GGATHLHKYIDARHKQYG----------PIFRER-LGGTQDAVFVSS 113

315a1ps         VVGTLLDLIAA--GGATHLHKYIDSRHRQYG----------PIFRER-LGGTQDAVFVSS 107

6a2m            NMVGFRKN-----RVMHDFFYDYYNKYRKSGF-----------PFVGFYFLHKPAAFIVD 85

6a2ps           NLVGFRKN-----RVIHDIFYDYYNKFRTSGS-----------PFVGFFFLQKPAAFIVD 85

6a8m            NMEELQKT-----KNIHEIFQDHYNKFRESKA-----------PFVGFFFFQSPAAFVID 88

6a18m           NMEGYKKT-----RTVHEIHQEYYNKYRNSKA-----------PFVGFYLFQKPAAFVID 88

6a8ps           NMQGVFTK-----RNVHEILKKYYEKYRESKV-----------PFVGFYFFQKPSAFILD 88

6a9m            SLTGVQTS-----RSFSAIWMDYYNKFRGTG------------PFAGFYWFQRPGILVLD 87

6a21m           SMKGVRTA-----RSFNEIWTSYYNKFRGSG------------PFAGFYWFRRPAVFVLE 87

6a21ps          SMWGLRTT-----RTFNDVWTDYYKKYRLSG------------PFAGFYWFQRPAVFVLE 89

6a17m           NIKDWPNK-----RHIAEIFRDYYFKYKN-----------SDYPFAGFFFFFTRTAVVTD 84

6a23m           NMKDWPKK-----RHIAMIFRDYYTKYKR-----------SVYPFAGFYFFFTRSAVITD 85

6A17ps          NIGDWPKK-----RQIAVIFRDYYRKYKN-----------ANYPFAGFYFFFTRSAVVTD 85

6A23ps          SMWGLRTT-----RTFNDVWTDYYKKYR------------LSGPFAGFYWFQRPAVFVLE 84

6a20ps          NTSELMKT-----RQIADLFRETYFKYKG----------KTDGPFVGFYLYLKKIAIVTD 86

6a20m           NTSELMKT-----VHFADIFKRTYNKLRN----------KTDGPFVGFYMYFKRMVVVTD 96

6a19m           NTGELWRT-----MPLAGILKRTYLKFRK----------QTDGPFAGFYLYAMKYIVITD 86

6a22m           NMEGFRKN-----KHFIDIVTPIYEKFKG-----------NGAPFAGFFMMLRPVVLVTD 85

6A22ps          NMDGLRRT-----KHFKDIVTPLYERFKD-----------SGAPFAGIYMMLRPVVLVLD 85

6a13m           NMSGLGRD-----LHWTDINLRIYRKFRG------------VERYCGYFTFMTKSLFIMD 84

6A13ps          NMSGLGKG-----LHWTDINRRIYEKFSK------------TERFCGYFTFFSKAFFVMD 84

6a14m           NMRGIVKK-----YHFRDINQRIYKKFKG------------QGPIAGMYTFFKRTALITD 94

6A14ps          NVKGIGTK-----YHFRDINQRIYDKFKG------------VAPFAGMFTFFKRSALIID 75

6a15pm          ------------------------------------------------------------

6a16m           HFFRLQS------VHYSELLQETYDAFRG------------SAKVAGTYVFLRPMAVVLD 83

6A16ps          HFFKMKS------VRLTELLQETYDAFKG------------SALVAGTYVYLRPIAVILD 83

6u1m            NIKGVVSG----KRHAQDALQDIYTAYKGRA------------PFVGFYACLKPFILALD 85

6u1ps           NIKGVVGG----KRHLQDALQVIYAKYKGRA------------PFVGFFACLKPFVLVLD 88

317a1m          IIRQIMTQTLSTEAMKAEHYSAIYKKFKGSG------------PFCGFYALLQPRALILD 93

317a1ps         IVRQIVTQSLSTEAMKTAHYSALYSKFKGSG------------PFCGFYALLQPRALILD 93

6g1m            NTKVVFKMEN----SFGMHLSEIYNDPRLKDE-----------AVVGIYSMNKPGLIIRD 88

6G1ps           NTEPAFKLKN----SFGLHLSEIYSDPKMQDE-----------AVVGVYALNKPCLIIRD 88

6w1m            CTREFLTAKV----PFFEQIQKFHEAPGFENE-----------PFVGVYMTHRPALVIRD 85

6w1ps           DTVGFLTGRL----PFFDQIRKFHEAPGLENE-----------PIIGVYLAYRPALVIRD 87

6v1m            NLSRVLRLEE----SFALQLRRFYFDERFRNE-----------PVVGIYLFHQPALLIRD 89

6v1ps           NLSKVLRLEE----SFALQLRRFYFDERFRNE-----------PIVGIYLFHQPALLIRD 89

6g2m            NLMGLLNMRM----SPAEFISQLYNHPDAENE-----------PFVGIHVFHKPALLLRD 87

6g2ps           NLAGLLSMRD----SPADFMGQLYNHPDALNQ-----------PFVGIHVFHRPALLLRD 87

6t1m            NVWNLLRGAC----CFGDQFRELYESKEAAGR-----------AFVGIDVLHNHALLLRD 106

6t2pm           ---NVLNVEC----CFGDQFRELYERKEAAGR-----------AIVGINVLHSHALLLRD 97

6t1ps           NVWKLLRGSC----CFGDQFRQLYESKEAAGH-----------AYVGIHVLHNHALLLRD 110

6t3m            NLGQLLFLRI----SFGDLFRQLYADPRNGQA-----------KIVGFFIFQTPALMVRD 87

6t3ps           HLRKLLLLRI----SFGDLFHNIYADPRGGQA-----------KVVGFFLFQTPALMVRD 87

9b1m            N-MAASALQ-----KASFQKQISEFYNRTRHH-----------KLVGLFNLRTPMIQIND 86

9b2m            N-MAAAALQ-----KSSFQRQLTEFYERTRQH-----------KLVGFFNMRTPMITLND 86

9B2ps           N-IGTSMLG-----LTSFHKVLSAFYNRTRGH-----------KVVGFFNLRTPMIQLND 86

9f2m            N-MAGMFLR-----KRAMFDIVCDLYTKGGSK-----------KFFGIFEQRQPLLMVRD 85

9f3pm           N-MAGMFLR-----KRAMLDIVCDLYTKGGSG-----------KFFGIFAQRQPLLMVRD 85

9F2ps           N-MAQMFLR-----QKAMFDIVCDLYNKGGSN-----------KVYGIFEQRQPLMMIRD 85

9c1m            N-IPWSVLMG----KESYIKHSIDLHLRLKQH-----------KVYGVFNLRDPLYYLSD 87

9c1ps           N-IPLAVLMG----KASYLKHSIAVHMRLKQH-----------KVYGVFNLRDPLFFLSD 87

9h1m            N-IPLKAMIG----GMPVLKKMIELHTKHTGS-----------PVYGIYALRDAVFFVRD 88

9h1ps           T-IPIRGMFT----GLPVLKYMIEQHMQYQGS-----------RVYGVYALRDPLIFLRD 88

6d2m            VMDTVMKQER----SLGMALADIYARHEG--------------KIVGIYMLNKRSILIRD 82

6d2ps           ILDTVMKQEM----SLGMVLSDIYKRHKG--------------KIVGIYMMNKRSILVRD 83

6d4m            CLDSVWRQEK----SMGLAIYDVYVKSKE--------------RVLGIYLLFRPAVLIRD 84

6d4ps           CLDSVWRREK----GMGMAIYDAYQKSKE--------------RFLGIYLLFRPAVLVRD 84

6d5m            ALESVTKGKR----SFGMAIYDMYKSTKE--------------PVIGLYLTLRPALLVRD 82

6D5ps           ALDSVRRGKR----SFGMAIYDMYNATKE--------------PVMGMYLTLRPALLVRD 82

310a1m          FLQKAYRREF----RHVEAICEAYQSGKD--------------RLLGIYCFFRPVLLVRN 81

310a1ps         FLHQAYRREF----RHVEAICEAYQMGRE--------------RLLGIYCFFRPVLIVRN 81

28a5m           NYPNMFTMKR----HAIYDLDDIYRQYKNKYD------------AVGIFGSRSPQLLVIN 86

28A5ps          NYPHMYTMKR----HAIYDLNDIYVKYKNKYD------------AVGIFGGRVPQLLVIS 86

28d1m           SFPSVFTQKR----NVVYDIDEIYEQYKNTDS------------IVGVFQTRIPQLMVTT 88

28d1ps          SFPSVFTQKR----NMAYDIDEIYRQYKNTES------------VVGVFNTRIPQLMILC 88

28d2m           SFPSIFTRKR----NIAYDIDDIYEKYKDTDN------------MVGVFTTRVPQLLVMC 88

28c1m           SFPNMIWPRQ----HFTMDMRDIYMHYRNTHS------------YVGCYLLRAPKLLVLE 86

28c1ps          SFPNMVWPRQ----HFTMDMRDLYMKYRETDS------------YVGTFLLRSPKLLLLE 86

309a1m          SYPGILINKSR---SLILDVQDVYNKYKDKYR------------TVGTFITRQPQLLVLD 90

309a1ps         TYPGVLADKSR---SLILDVQEVYNKYKEKHR------------AVGTFLTRQPQLLVLD 90

309a2m          TYPGLLTRKS----NLVFDVQKIYDKYKGKHR------------AVGVFVTRQPQILVLD 89

309a2ps         TYPGLLTRTS----NLVEDVQKVYDKYKGKHR------------AVGVFVTRQPQILVLD 89

308a1m          NMLDFALGRR----SYGEIYQEIYTRNPGLKY------------VGFYRLFNEPAILVRD 83

308a1ps         NMASFALGQR----SYGEVYEQIYRQHPELRY------------VGFYRLFNEPAILVRD 89

4aa1m           N--CMLVT------DKDLMRRCAGKAFDLYG------------SLVRIWVLLFPFFAVLE 102

4aa1ps          N--CLLIK------DKDLMRNQAAKAFDLYG------------SLVRIWVLFFPFFVVLQ 113

4C3m            NAIEMNV-------DHDELFNRVIGMQKLWGTR-I--------GINRVWQGTAPRVLLFE 112

4C3ps           NAIEMNV-------DHDELFNRVIGMQKLWGTR-L--------GINRVWQGTSPRVLLFE 112

4d1m            HGHHFIGK------PPHEMVKKIFEFMETYSK--D--------QVLKVWLGPELNVLMGN 88

4D1ps           HGHHFIGK------PPHELVKQITEFMSKYAK--D--------ETLKVWLGPELNVLMAN 88

4d1malt         NAHIFLGL------TPAEACLKIGELAERHG------------DTFGLFLGPSYSVMLFN 80

4D1psalt        DAHLFFGL------SPAEACLMMGQLAEKYG------------DTFKLRLGPCFSVMFFH 90

4s3m            NV------------KKGEILNWLKELREKHG------------PVFRIWFGKDLMVMFTD 81

4s3ps           NV------------KKGEILNWLKELRERHG------------PVFRIWFGKDLMVMFSD 81

312a1m          HLHILAKL------VGPHPLRRATEMINEHLH--D--------HRAKLWMGTKLYLVDCN 88

312a1ps         HLHILAKL------VGPHPFRRATELVNTHLK--D--------HRGKLWLGTKLYLVDCN 89

4g1m            QAHVAAGL------SNAEILAVGLGYLNKYG------------ETMKAWLGNVLLVFLTN 109

4G1ps           QAHMVAGL------SNAEILNVGLGYLNKYG------------ETMKAWLGNVLLVFLTN 107

4g15m           HLFDVIG-------PASSVFRTVIRKSAPFE------------HIAKMWIGPKLVVFIYD 97

4G15ps          HLFDVIG-------PASSVFKTVIRKSAPFE------------HIAKMWIGPKLVVFIYD 97

4d2m            NLLMYRGL------DPEQIMDFVKKNQRKYG------------RLYRVWILHQLAVFSTD 83

4D2ps           NALMYRGL------DAEQIMGFVSKNRNKYG------------PLYKVWVLNQLAVFSTD 84

4d14m           NAPLLINE------SPKTIFDMQFRLIAEFG------------KNIKTQMLGESGFMTAD 85

4d14ps          NAPLMINE------SPKTVFDLQWRLIQTHG------------KNVRCQILQDRGFMTAD 85

4d8m            AMQLMLRL------NPKTFIKVGREYVLKFG------------HLQRVWIFNRLLIMSGD 83

4d8ps           ALHIMSSM------NPKTFIKVSGENMRKYG------------PLQRVWILNRLLIMSAD 83

4ae1m           AAWQMRSF------QPDNLHDKFAEYVKRFG------------RSFMGTVLGHVVMVTAE 86

4AE1ps          AAWQMRSF------QPDNLHEKFAEYVERFG------------RSFMASVCGQVIMVTAE 86

4d20m           CGLQALHL------GAENIIGWVGEKFDKYG------------KTFRFWILGESLIYTKD 85

4D20ps          NGLQALDL------GAENIVDWVEESFRLYG------------KTFRMWILGESLIYTKD 86

4d21m           NGLQALTL------RPENFIQRFGDYFNKYG------------KTFRLWILGECLIYTKD 85

4e2m            NAHQMGK-------NPSEILDTVFSWWHQYGK-----------DNFVFWIGTYSNVLVTS 85

4e2ps           NAHQAGK-------NPTEILDQVFSWWHQYGK-----------DNFRFWIGSYSNLIITN 85

4e1m            NAHQMGN-------TPTEILNRFFGWWHEYGK-----------DNFRYWIGYYSNIMVTN 85

4e1ps           NAHQLGR-------TPPEILGQMFEWWYQHDK-----------DNFRYWIGYYPNLMVTR 85

4e3m            NANRIGK-------NPAEILSTFFDWWYDYGK-----------DNFLFWIGYSSHIVMTN 85

4e3ps           NANRVGN-------TPAEILATIFDWWQEYGK-----------DNFVFWIGYTPHLAVTN 85

4ad1m           NLFQFGL-------KPAEYPKKVLQYCRKYDF-----------QGFRSLVFLQYHMMLSD 87

4AD1ps          NIFQFGL-------KPAEYPKKVLQYCRKYDF-----------QGFRSLVFLQYHMMLSD 87

4p1m            NTLDLYG-------RDHAGVFNYSRERAKEMGT----------SYIEYVFGKAIYNIIDA 99

4p3m            NSFDLYG-------KDHSGVFEHSRDCAKKLGK----------SYAEYAMGTAIYNVIDA 99

4p1ps           NCFDMYG-------KDLAGVFSYSRELSQRLGE----------SYLEYGMGVPLLNIIDA 99

4P2ps           NCFDLLG-------KDTDQVFTHLRQLAKNSGD----------SYLQYSMGFSNFNVIDA 101

4P3ps           HCFDLYG-------KDNAGVFKFTRDLSKTLGK----------SYVRYVVGMPIYNVIDA 99

4p2m            NCFDLLG-------KDTDQVFTHLRQLAKNSGD----------SYLQYSMGFSNFNVIDA 101

4ac1m           NNLDILN-------FTPASVFNFVRESTAKAKGQ---------NYLWYFLYAPMYNVVRP 101

4AC1ps          NNLDVLN-------CTPSSLFNFLRDSAAKAQGR---------NFLWYFLFAPMYNVIRA 101

4ac2ps          NNFDLLN-------FTPSTVFNFMRDSCANARGR---------NYLWYFFGSPMYNVIRA 101

4ac2m           NNFDLVN-------FTSESIFNFMRDASAKAKGR---------NYLWYFFHAPMYNIVRA 102

4ac3m           NNLDLLN-------LTPANIFSYIRESTAKANGQ---------NYIWNFLFAPEYNIVRA 101

311a1m          NAQMVGK------RLPEYIFLVFTELRDRFG------------ATYRLRLGPQLWVFLHS 81

311a1ps         ------------------IFLVFTELRDRFG------------ATYRLWLGPQLWVFLHT 30

316a1m          AMHKLLFL------TPINFFQRSTEYLTKYG------------TFSRCWVFHRLFIPLAD 83

316A1ps         AMHKLLFL------KPQNFFQRSHEYLAKYG------------AVTRLWVFHRLFMPLAD 83

313a2m          NSVRYLIIS-------RGRMSSRTTYMDKHG------------STYMAWIGTTPIVITRD 83

313a3m          IAFEYLITY-------KRKMSIRTKYMDIYG------------STCLVWVGPTPFVITRD 83

313a1m          SSLENIITY-------KRKLSFRTKYLNKYG------------STILTWMGPVPFIVTRD 83

313C1ps         VAVEYLRN--------KHNMEQRSKQFQEYG------------PTNLTWIGSVPVLVTCE 82

313C2ps         SVVGFLRN--------KRNIGLAGKVAEKYG------------PTFLTWMGTVPVLVTSE 82

313a5m          LAFEYIRL--------KRKIRLRTILFKIYG------------KTVLTWIGLTPVLVTCE 82

313a4m          MAHWLMRR--------EDILNAFGCFLDKHG------------PTIFSWLGPIPFMIVSD 82

313a4ps         MAHKLMRR--------EDILNEFGIYMAKHG------------PTIFSWLGPIPFMIVSE 82

313A4bps        MAHKLIHR--------EDILNEFGIYLAKHG------------PTIMSWLGPIPFVIASD 82

313b1m          MGLQMMNP--------ETFLQYMDGLSRQFK------------APFISWMGTSCFLYIND 82

313b1ps         MGLQMMNT--------ETFLQYMDKLSHKFK------------APFVSWMGTSCFLYVND 84

318a1m          LLLCINLHP-------NSILEKVSQYRVHFQ------------RPLAVLVGTRVLLYIDD 86

318A1ps         FLLCINLHP-------NSILERVTQMRKYFQ------------RPLAILVGTRVLVYIDD 86

18a1m           YLLFMGSEK----------HTRFMELAKQYGS------------LFSTRLGSQLTVVMSD 102

18a1ps          YLLFMGNEK----------HTRFMELAKQYGS------------LFSTRLGSQLTVVMSD 103

306A1m          YLPFLDARAP---------HKSLQKLAKRYGG------------IFELKMGRVPTVVLSD 98

306A1ps         YLPFLSRRAP---------HKSLQALARRYGG------------IYQLRMGSVKAVILSD 103

303a1m          SALQVSQLRC----RLGMFCKVIDVFARQYVNP---------YGFYGLKIGKDKVVIAYT 85

303A1ps         SALQISQLRC----RLGMFCKVIDVLASRYVNP---------YGFFGLKIGKDKVVIAYT 85

305a1m          NTLQFRKEAS----AVGGQHILFERWAKDFRS-----------DLVGLKLGREYVVVALG 85

305A1ps         NTLQFRKEAR----AVGGQHILFGQWAQRYQS-----------QLLGLKLGQEYVVVALG 85

304a1m          SYLFMLIINF----KY--LHKAALTLSRWYKS-----------DIIGLHVGPFPVAVVHS 83

304a1ps         SYLFLLLINY----KY--LHKAALTLTRWYKS-----------DIIGLHVGKFPVAVVHS 83

307a1m          NLHLLDRYRD----SP---FAGFTALAQQYGD------------IYSLTFGHTRCLVVNN 106

307a1ps         NLNVLDKYRD----NP---FEGFTELAKKYGD------------IYSLTFGHTRCLVVNN 101

307a2pm         NINLLGRFQY----NP---FYGFGTLTKKYGD------------IYSLSLGHTRCIVVNN 102

307a2pps        NLDLLGRFKS----NP---FEGLGALTKQYGD------------IYSLTLGHSRCLVVNS 102

 

                    4A                                    4F 4H

                     4B         4C    4D               4E  4G         4I

12a4m           PQDFEVVFRNEGVWPNRPGNYTLLYHREEYRKDFYQGVMGVIPTQGKPWGDFRTVVNPVL 165

12a5m           PKDFEVVFRNEGVWPFRPGSDILRYHRTVYRKDFFDGVQGIIPSQGKSWGDFRSIVNPVL 165

12A4ps          PKDFEVVFRNEGVWPNRPGSDTLRYHRQTHRKDFFQGVEGVIPTQGKTWSDFRSTVNPVL 164

12A5ps          PKDFEVVFRNEGVWPHRPGSDTLRYHRKTHRKDFFQGVEGAIPTQGKTWSDFRSAVNPVL 164

12c1m           VETFEKVYRTEGQWPVRGGAEPVIHYRNKRKDEFFKNCMGLFGN-GAEWGKNRSAVNPVL 157

12c1ps          VENFERIYRAEGQWPVRGGADPVLHYRANRKDGFFKDCVGLFSN-GPEWGRLRSAANPVL 167

12e1m           PQDYEVIFRNEGQYPYRRSFEVMDYFKRVHRREVFDGYDGLTSGNGPAWGKMRTAVNPIL 147

12e1ps          PQDYATVFRNEGQWPHRRSFTTVEYFRKVRRPEVFGEYDGLLSGNGAAWGKMRTAVNPIL 149

12d1m           TKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIF 159

12d1ps          TGDIATVFRNEGAWPHREAFDSIVHFRQHIRPDVYGRTLGLTVGQGEDWGKMRSAVNPIF 159

12b2m           PDDFEMTYRNEGVWPIRIGLESLNYYRKIHRPDVFKGVGGLASDQGQEWADIRNKVNPVL 170

12B2ps          PEDFELTYRNEGVWPIRIGLESFSYYRKVKRPDVFGGIGGLVSEQGKDWADIRNKVNPVL 173

49A1m           GDEIRNIFKKEEAMPHRPSMPSLRHYKGDLRRDFFGDVAGLIGVHGPKWEAFRQEVQHIL 221

49A1ps          GDEIRNIFKKEEAMPHRPSMPSLRHYKGDLRRDFFGDVAGLIGVHGPKWEAFRQEVQHIL 226

301a1m          ADEIEKCYRSEGPTPFRPSMPSLVKYKSVVRKDFFGDLGGVVGVHGEPWREFRSRVQKPV 193

301A1ps         ADEIEKCYRSEGPTPFRPSMPSLVKYKSVVRKDFFGELGGVVGVHGEPWRQFRSRVQKPV 198

302a1m          PKDIALLLNE-RDCPQRRSHLALAQYRKSRPD--VYKTTGLLPTNGPEWWRIRAQVQKEL 138

302A1ps         PKDIAKLLNE-RDCPQRRSHLALAQYRRQRPH--VYKTTGLLPTNGPEWWRLRSQLQKEL 138

314a1m          RDDLEKVLKYPSKYPFRPPTEIIVMYRQSRPD--RYASVGIVNEQGPMWQRLRSSLTSSI 177

314a1ps         REDLEKVLKYPSKYPFRPPTEIIVMYRQSRPD--RYASVGIVNEQGPMWQLLRTSLTSSI 178

315a1m          ANLMRGVFQHEGQYPQHPLPDAWTLYNQQHAC-----QRGLFFMEGAEWLHNRRILNRLL 168

315a1ps         APLMRGVFLHEGQYPQHPLPDAWTLYNQRHAC-----QRGLFFMEGAEWLHNRRILNHLL 162

6a2m            TQLAKNILIKDFSNFADRGQFHNGR--------DDPLTQHLFNLDGKKWKDMRQRLTPTF 137

6a2ps           TKLAKNILIKDFSNFADRGQFHNER--------DDPLTQHLFNLDGKRWKELRQRLSPTF 137

6a8m            LELAKQILIKDFSNFSNKGIFYNEK--------DDPISAHLFNLDGAQWRLLRNKLSSTF 140

6a18m           LELAKQILIKNFSNFTDKGIYYNEK--------DDPMSAHLFNLDGPQWRLLRSKLSSTF 140

6a8ps           LDLAKHILIKDFSNFSDKGLFYNEK--------DDPISAHLFNLDGPQWKVLRNKLTSTF 140

6a9m            ISLAKLILIKEFNKFTDRGFYHNTE--------DDPLSGQLFLLDGQKWKSMRSKLSYTF 139

6a21m           TSLAKQILIKEFNKFTDRGFFHNPE--------DDPLSGQLFLLDGQKWRTMRNKLSSTF 139

6a21ps          PSLAKLILIKEFNKFTDRGFFHNPE--------DDPLSGQLFLLDGHKWKSMRHKLSSTF 141

6a17m           MELLKRVLIKDFNHFENRGVFYNEI--------DDPLSATLFSIEGQKWRHLRHKLTPTF 136

6a23m           LELVKRVLIKDFNHFENRGIFYNEI--------DDPLSATLFSIEGQKWRHLRHKLTPTF 137

6A17ps          LDLVKRVLIKDFNHFENRGIFYNEI--------DDPLSATVFSIEGQKWRHLRHKLTPTF 137

6A23ps          PSLAKLILIKEFNKFTDRGFFHNPE--------DDPLSATVFSMKGQKWRHLRHKLTPTF 136

6a20ps          IDFVKTVLIREFDKFHDRGLFHNEK--------DDPLTNHLVAIEGQKWRQLRQKMTPTF 138

6a20m           IDFAKTVLIREFDKFHDRGVFHNER--------DDPLSANLVNIDGQKWKTLRQKLTPTF 148

6a19m           VDFVKTVLIRDFDKFHDRGVYHNEK--------DDPLTNNLATIEGQKWKNLRQKLTHTF 138

6a22m           LELAKQILIQDFANFEDRGMYHNER--------DDPLTGHLFRIDGPKWRPLRQKMSPTF 137

6A22ps          LDLAKEVLIRDFANFEDRGMYHNER--------DDPLTGHLFRIDGPKWRPLRHKMSPTF 137

6a13m           LELIRDIMIRDFSSFADRGLFHNVR--------DDPLTGNLLFLDGPEWRWLRQNLTQVF 136

6A13ps          LELIKKITISDFSSFADRGLFHNVK--------DDPLTGNLLFLDGPEWRWLRQNLTQVF 136

6a14m           LDFIKQVMIKDFSYFQDRGAFTNPR--------DDPLTGHLFALEGEEWRAMRHKLTPVF 146

6A14ps          LDLIKQVLIKDFQYFQDRGVFNNVR--------DDPLTGHLLTLEGDEWRSMRQKLTPVF 127

6a15pm          ------------------------------------------------------------

6a16m           LDLVKAVLIRDFNNFVDRRSFHG-----------DPLTANLFNLQGEEWRNLRTKLSPTF 132

6A16ps          LDLAKTILDKDFDKFVDRRNFHK-----------EPLMDNLFNAQGEEWCTLRKKLTPMF 132

6u1m            LKLVHQIIFTDAGHFTSRGLYSNPS--------GEPLSHNLLQLDGHKWRSLHAKSAEVF 137

6u1ps           LELVRHILVTHAGNFTTRGLYSNDG--------SEPLSGNLLQLDGHKWRALHAQSTGVF 140

317a1m          RELIRQIMIKDFWNFNDRGLYCNQK--------SDPLSGDLYALRGESWKEMRQKLDPSL 145

317a1ps         RELIRQIMIKDFWNFNDRGLYCNQK--------TDPLSGDLFAMRGQSWKEMRQKLDPSL 145

6g1m            IELIKSILIKDFNRFHNRYARCDPHG-------DPLGYNNLFFVRDAHWKGIRTKLTPVF 141

6G1ps           PELIKSVMVKDFNRFHNRYGRCDPHG-------DPLGSNNLFFVRDTHWKDIRTKLTPVF 141

6w1m            LELIKTVMIKKFQYFNNRVLQTDPHN-------DALGYKNLFFARSPGWRELRTKISPVF 138

6w1ps           LDLVKTVMIKKFSYFTNRKLQTDPHD-------DALGYNNLFFVRSPEWKELRNKISPVF 140

6v1m            LQLVRTVLVEDFVSFSNRFAKCDGRS-------DKMGALSLFLAKQPEWREIRTRLAPAF 142

6v1ps           LSLVRTVLVEDFVSFSNRFAKCDLRH-------DKMGSLNLFFAKQPEWREIRTRLSPVF 142

6g2m            PEMVRNILVKDFAGFSNRYSSSDPKG-------DPLGSQNIFFLKNPAWKEVRLKLSPFF 140

6g2ps           PDLIKRILIKDFGKFSNRYSNSDYKG-------DPLGSQNIFFLKNPAWKEVRFKLSPFF 140

6t1m            PALIKRIMVEDFAQFSSRFETTDPTC-------DTMGSQNLFFSKYETWRETHKIFAPFF 159

6t2pm           PALIRRILVEDFPEFSSSFKSTDAIR-------DTMGSGNLLFTKYKTWWETHKIFA--- 147

6t1ps           PALIKRILVEDFSQFSSRFETTDPIG-------DTMGAQNLFFSKHETWRETHKIFAPFF 163

6t3m            PELIRQVLIKNFNNFLNRFESADAG--------DPMGALTLPLAKYHHWKESRQCMSQLF 139

6t3ps           PELIRLVLIKHFNSFLNRYEAADAAG-------DPMGSLTLPLAKYHNWRESRQSMAQLF 140

9b1m            PQLIKKICVKDFDHFPNHQTLNIPN--------ERLVNDMLNVMRDQHWRNMRSVLTPVF 138

9b2m            PELIKKVCVKDFDHFPNHQPFITSN--------DRLFNDMLSVMRDQRWKHMRNTLTPVF 138

9B2ps           PEIIKKICIKDFDHFPNHQLFLESN--------ERLLNDMLSVMRDQRWKHMRNTLTPVF 138

9f2m            PDLIKQITIKDFDHFINHRNVFATSSDDDPHDMSNLFGSSLFSMRDARWKDMRSTLSPAF 145

9f3pm           PDLIKQITIKDFDHFINHRNEFDTSSDDDPHDMSNLFSSSLFSMRDARWKDMRSTLSPAF 145

9F2ps           PDLLRQITIKDFDHFINHRNLFGTGTDDDPHDMSNLFGSSLFSMRDARWKDMRSTLSPAF 145

9c1m            PELIRQVGIKNFDTFTNHRKGITEGFN-----DTSVISKSLLSLRDRRWKQMRSTLTPTF 142

9c1ps           PELIRQVGIKSFDNFANHRKGLGDAGGG---ANDSVLSKSLLSLRDRRWKQMRSTLTPTF 144

9h1m            PELIKLIGIKEFDHFVNHNS----MHNN---IQESILSKSLISLRDGRWKEMRNILTPAF 141

9h1ps           PDLIKLVGIKEFDHFVNHHS----MHNN---VQESILSKSLISLKDARWREMRYILTPAF 141

6d2m            AQLARQIMTSDFASFHDRGVYVDED--------KDPLSANLFNLRGASWRNLRQKLTPSF 134

6d2ps           AQLARQIMTSDFASFHDRGVYVDEK--------NDPLSANLFNLRGASWRNLRKKMTPSF 135

6d4m            ADLARRVLAQDFASFHDRGVYVDEE--------RDPLSANIFSLRGQSWRSMRHMLSPCF 136

6d4ps           AALARRVLAQDFASFHDRGVYVDEV--------NDPLSGSIFALRGQSWRSMRHKLSPCF 136

6d5m            AQLAHDVLVKDFASFHDRGVYVDEK--------NDPMSASLFQMEGASWRALRNKLTPSF 134

6D5ps           PQLAHDILVKDFASFHDRGIYVDEK--------NDPMSATIFAMEGSNWRNLRAKLTPSF 134

310a1m          VELAQTILQQSNGHFSELKWDY---------------------ISGYRRFNLLEKLAPMF 120

310a1ps         VELAQTILQQSNGHFNDLKWDY---------------------VKGYRRFNLLEKLSPIF 120

28a5m           PALARRVFVSNFKNFHDNEIAKNIDEKT-----DFIFANNPFSLTGEKWKTRRADVTPGL 141

28A5ps          PELARRVFVSDFKHFHDNEVSNLIDEKS-----DFIFANNPFSLTGDKWKQRRADVTPGL 141

28d1m           PEYAHKIYVSDFRSFHDNEMAKFTDSKT-----DPILANNPFVLTGEAWKERRAEVTPGL 143

28d1ps          PEYAHKIFAGEFRSFHDNEIGKFTNKKV-----DKILANNPFILTGEDWKERRAEITPGL 143

28d2m           PEYIHKIYATDFRSFHNNEWRNFVNKKT-----DMILGNNPFVLTGDEWKERRSEIMPAL 143

28c1m           PRLVYEIYVSAFSHFENNDASKMVDIAK-----DRLVALNPFVLEGEEWRHQRAVFSTLL 141

28c1ps          PRLVYEVFVSAFRHFEDNDAARMVDTGK-----DVLVCCNPFVLEGNEWRQQRGIFSSLL 141

309a1m          PALAHEILVDKFSHFRDTITSSFVGHNPD----DKYVAGSPFFSAGDKWKRLRSENVGGL 146

309a1ps         PALAHEVLVDKFSHFRDTVTSSFVGHNPD----DRFVQVSPFFSAGDDWKRRRTESGGGI 146

309a2m          PELAHEVLVSNFRCYKDSLQSSYLRHAKW----DKYARLNPFWASGQSWRRLRTDAQAGI 145

309a2ps         PELAHEILVLNFRCYKDSLTSSYIRHARW----DKYARRNPFWASGQSWRSLRTDAQAGI 145

308a1m          QELLRQILVG--RNFADCADNAVYVDHQR----DVLASHNPFIANGDRWRVLRADLVPLF 137

308a1ps         QRLVREVLVG--SSFLNCADNAVNVDAQR----DVLATCNPFIASGDRWRILRADLVPLF 143

4aa1m           PEDLQVILSSKKHTNKVF-FYRLMH---------NFLGDGLITSSGSKWSNHRRLIQPAF 152

4aa1ps          PEDLQVILSSQKHTNKVF-IYQLMH---------NFLGDGLITSSGLKWSTHRRLIQPAF 163

4C3m            PETVEPILNSQKFVNKSH-DYDYLH---------PWLGEGLLTSTDRKWHSRRKILTPAF 162

4C3ps           PETVEPILNSQKFVNKSH-DYDYLH---------PWLGTGLLTSTDRKWHSRRKILTPAF 162

4d1m            PKDVEVVLGTLRFNDKAG-EYKALE---------PWLKEGLLVSRGRKWHKRRKIITPAF 138

4D1ps           PKDVEVVLGTMRFNDKAG-EYKALE---------PWLKEGLLVSRGRKWHKRRKIITPAF 138

4d1malt         PRDVERVLGSSQLLTKSQ-EYSFLG---------RWLNEGLLVSNGRKWHRRRKIITPAF 130

4D1psalt        PSDVEQVLSSTQLVDKAD-EYDFLA---------RWLNEGLLVSTGRKWHKRRKIITPAF 140

4s3m            PEDIKQLLGNNQLLTKSR-NYELLE---------PWLGKGLLTNGGESWHRRRKLLTPGF 131

4s3ps           PEDIRQLLGNNSLLYKSR-NYALLE---------PWLGKGLLTNGGESWHRRRKLLTPGF 131

312a1m          PKDIQALCSAQQLLQKTN-DYRVFE---------NWLCEGLFTSGFEKWSHRRKIVMPAF 138

312a1ps         PKDIQALCSAQQMLQKTT-DYKVFE---------NWLCEGLFTADYDKWFQRRKTLTPAF 139

4g1m            PSDIELILSGHQHLTKAE-EYRYFK---------PWFGDGLLISNGHHWRHHRKMIAPTF 159

4G1ps           PNDIELILSGHQHLTKAE-EYRYFK---------PWFGDGLLISNGHHWRHHRKMIAPTF 157

4g15m           PRDVELLLSSHVYIDKAS-EYKFFK---------PWLGDGLLISTGQKWRSHRKLIAPTF 147

4G15ps          PRDVELLLSSHVYIDKAS-EYKFFK---------PWLGDGLLISTGQKWRSHRKLIAPTF 147

4d2m            PRDIEFVLSSQQHITKNN-LYKLLN---------CWLGDGLLMSTGRKWHGRRKIITPTF 133

4D2ps           PHDIEFILSSQQHITKNN-LYELLH---------CWLGTGLLMSTGKKWHSRRKIITPTF 134

4d14m           SKMIEAIMSSQQTIQKNN-LYSLLV---------NWLGDGLLISQGKKWFRRRKIITPAF 135

4d14ps          PKMIEAIMSSQQTIQKNN-LYGLLV---------NWLGDGLLLSKGKKWFRRRKIITPAF 135

4d8m            AELNEQLLSSQEHLVKHP-VYKVLG---------QWLGNGLLLSDGKVWHQRRKIITPTF 133

4d8ps           SEINEQLLSSQEHLVKHP-VYRVLG---------KWLGNGLLLSDGKVWHQRRKIITPTF 133

4ae1m           PRHIDALLQGQHQLKKGT-MYFALR---------GWLGDGLLLSRGKEWHTMRKIITPTF 136

4AE1ps          PSHVDALLHSQKQLRKSS-IYGALR---------GWLGNGLLLSQGEQWHGMRKIITPTF 136

4d20m           LQYFETILSSTTLLEKGQ-LYEYLR---------PFLNDGLLVSTGRKWHARRKIFTHAF 135

4D20ps          LKYFEAILGSTTLLQKGQ-LYKFLR---------PFLNDGLLLSVGKKWHARRKVFTNAF 136

4d21m           LKYFESILSSSTLLKKAH-LYRFLR---------DFLGDGLLLSTGNKWTSRRKVLAPAF 135

4e2m            SKYLEFILSSQTLITKSD-IYQLTH---------PWLGLGLLTSTGSKWHKHRKMITPAF 135

4e2ps           HKYLEFILSSQTLITKSD-IYNLTH---------PWLGLGLLTSTGSKWHKHRKMITPSF 135

4e1m            PKYMEFILSSQTLISKSD-VYDLTH---------PWLGLGLLTSTGSKWHKHRKMITPAF 135

4e1ps           TKYFEFILSSQTLISKAE-VYSLMQ---------PWLGLGLLTSTGSKWHKHRKMITPSF 135

4e3m            PKQLEYILNSQQLIQKST-IYDLLH---------PWLGHGLLTSFGSKWHKHRKMITPSF 135

4e3ps           PKYLEYILNSQSLIQKST-IYELLH---------PWLGYGLLTSHGSKWHKHRKMITPSF 135

4ad1m           PAEIQNILSSSSLLYKEH-LYSFLR---------PWLGDGLLTSSGARWLKHQKLYAPAF 137

4AD1ps          PAEIQNILSSSSLLYKEH-LYSFLR---------PWLGDGLLTSSGARWLKHQKLYMPAF 137

4p1m            DSAENVLN-HPNLITKGL-VYNFLH---------PFLRTGLLTSTGKKWHARRKMLTPTF 148

4p3m            DSAERVLN-DPNLINKGT-IYDFLH---------PFLRTGLLTSTGKKWHARRKMLSPTF 148

4p1ps           ENAENILN-HPKLITKSL-VYDFLQ---------PALRTGLLTSTEKKWHARRKMLTPTF 148

4P2ps           HNAANILN-HPNLITKGV-IYNFLH---------PFLRTGVLTATEKKWHARRKMLTRTF 150

4P3ps           ETAEMILTDQKSLIGKGC-VYNFLH---------PALKTGLLTSQGDKWHARRRMLTPTF 149

4p2m            HNAANILN-HPNLITKGV-IYNFLH---------PFLRTGVLTATEKKWHTRRSMLTRTF 150

4ac1m           EEAEEVFQ-STKLITKNV-VYELIR---------PFLGDGLLISTDHKWHSRRKALTPAF 150

4AC1ps          EEAEEIFQ-STKLITKNV-IYELLR---------PFLGEGLLISTDQKWHSRRKALTPAF 150

4ac2ps          EEAEEIFQ-STKLLTKNV-VYDLLR---------PFLGEGLLTSTDQKWHARRKALTPAF 150

4ac2m           EEAEEILQ-SSKLITKNM-IYELLK---------PFLGEGLLISTDQKWHSRRKALTPAF 151

4ac3m           EDAEEIFQ-STKITTKNM-SYELIR---------PFLGDGLLISIDQKWHTRRKTLTPAF 150

311a1m          AEETRQALHDP-TLRKAD-TFMQLE---------PLIGNGLLISHGAHWTRQRRLLTPAF 130

311a1ps         AEETREALHDP-TLRKAK-TFLQLE---------PLIGNGLLISHGSHWTQQRRLLTPAF 79

316a1m          LELSRQLLENDTHLETG---YELMK---------DWLVGGVLMCQSEQWQKRHSLISGLF 131

316A1ps         LELAKQVLQSEQHLETG---YELMR---------HWLGGGVLMCDKNQWTQRHGLIGSIF 131

313a2m          PKIAEKVLTSPFCINRSSQTTNALA---------LSMGYGLLTLQGSKWMARRKHMNPAF 134

313a3m          PKIAEEIFLSPECLNRSSIFSKPVN---------SCTGDGLLSLEASKWVDRRKNLNPAF 134

313a1m          PKVVEDIFSSPDCHNKSQHIVNAIT---------SCMGNGLLGKQDPHWLDRRKHFNPSF 134

313C1ps         PNVVQDVLTSPHCLDKSKIACNPLR---------LICGPATFALNGSHWVERRKQMNPSF 133

313C2ps         PNVIQDILTSPHCLDKSQTACNAII---------MNSGPGILALRGSHWVERRRKMIPSF 133

313a5m          PKILEDIFTSPNCSNRSSVVDKAIS---------SCLGLGLLTLKNNHWNERRKLLLPSF 133

313a4m          PQVVQDIFTSPHCVNKG-IIYKAVD---------DGAGVGLFSLKDPRWSIHRKLLNPAF 132

313a4ps         PQVVQDILTSPHCVNKG-IIYKAVD---------DGAGVGLFSLKDPRWSVHRKLLNPAF 132

313A4bps        PQVVQDILTSPHCVNKG-IIYRAVD---------DGMGVGLFSLKDPRWSVHRKLLNPAF 132

313b1m          PHSVEQILNSTHCTNKG-DFYRFMS---------SAIGDGLFTSSSPRWHKHRRLINPAF 132

313b1ps         PQTVEQVFNSNHCTNKG-DFYRFLS---------SAIGDGLFTFSAPRWHKHRRLINPAF 134

318a1m          PAGMECVLNAPECLDKT---FLQDG---------FFVRRGLLHARGQKWKLRRKQLNPAF 134

318A1ps         PAGMESILNAPECLDKT---FMQEG---------FFAKRGLLHARGQKWKLRRKQLNPAF 134

18a1m           YKMIRECFRR--EEFTGRPDTPFMQTLNG---------YGIINSTGKLWKDQRRFLHDKL 151

18a1ps          YKMIRECFRR--EEFTGRPDTPFMQTLNG---------YGIINSTGKLWKDQRRFLHDKL 152

306A1m          AALVRDFFRR--DVMTGRAPLYLTHGIMGG--------FGIICAQEDIWRHARRETIDWL 148

306A1ps         VTLVREFFRH--EVMAARAPLYLTHGIMGG--------YGIICAAGPIWKHQRRELIDWL 153

303a1m          NDAISEMMTN--EDIDGRPDGIFYRLRTFN------SRLGVLLTDGEMWVEQRRFILRHL 137

303A1ps         NDAISEMMTN--EDIDGRPDGIFYRLRTFN------SRLGVLLTDGEMWVEQRRFILRHL 137

305a1m          HEMVKEVQLQ--EVFEGRPDNFFLRLRTMG------TRKGITCTDGQLWYEHRHFAMKQM 137

305A1ps         HEMVREVQLQ--EVFEGRPDNFFLRLRTMG------TRKGITFTDGKLWYEHRNFAMKQM 137

304a1m          ADGVREILNN--QVFDGRPQLFVAAMRDPGQ-----DVRGIFFQDGPLWKEQRRFILRYL 136

304a1ps         GEGVREVLNN--QVFDGRPGIFLAAMRDPGD-----DVRGIFFQEGALWKEQRRFILRYL 136

307a1m          LELIREVLNQNGKVMSGRPDFIRYHKLFGG--------ERSNSLALCDWSQLQQKRRNLA 158

307a1ps         LELIREVLNQNGKVVSGRPDFLRYHKLFGG--------ERSNSLALCDWSQLQQKRRNMA 153

307a2pm         VDLIKEVLNKNGKYFGGRPDFFRYHKLFGG--------DRNN------------------ 136

307a2pps        LDLIREVLNKNGKFIGGRPDFIRYHKLFGG--------DRNNSLALCDWSNLQQKRRNLA 154

 

                              5C

                   5A       5B        5D   5E 5F                  5G

12a4m           MQPKNVRLYYKKMSQVNQEFVQRILELRDPD----------TLEAPDDFID 206

12a5m           MQPKNVRLYFKKMSQVNQEFVELIKEIRDAS----------TQEVPGNFLE 206

12A4ps          MQPKNVRLYYKKMSQVNQEFVQRIKTLRDVD----------TQEVPDDFIS 205

12A5ps          MQPKNVRLYYKKMSQVNQEFVQRIKALRDID----------TQEAPDDFLT 205

12c1m           MQHRNVAIYLKPMQRVNRQFVNRIREIRDKE----------SQEVPGDFMN 198

12c1ps          MQHRNANLYLEPMQRVNNQFIDRIRATRDKE----------SLEMPGDFLD 208

12e1m           LQPRNAKLYMTNLVQVSDEFLERIRIIRDPV----------TQEMPDDFAV 188

12e1ps          LQPRNAKLYLKNLVQVSDEFLERIRLIRDPV----------SQEMPDDFTE 190

12d1m           MQPRGLRMYYEPLSNINNEFIERIKEIRDPK----------TLEVPEDFTD 200

12d1ps          MQPRGLRMYFEPLSNINNEFIERIKEIRDPS----------TLEVPSNFND 200

12b2m           MKVQNVRQNLPQLDQISKEFIDKLETQRNPE----------THTLTTDFHN 211

12B2ps          MKVQNVRQNLPQLDQIAKEFIDKLESQRDPE----------THLLQDDFHD 214

49A1m           LQPQTAKKYIPPLNDIASEFMGRIELMRD-E----------KDELPANFLH 261

49A1ps          LQPQTAKKYIPPLNDIASEFMGRIEAMRD-E----------KDELPANFLH 266

301a1m          LQLSTIRRYLQPLEVITEDFLVRCENLLD-E----------NQELPEDFDN 233

301A1ps         LQLSTIRRYLQPLEAITDDFLVRCEHLLD-G----------NQELPKDFDN 238

302a1m          SAPKSVRNFVRQVDGVTKEFIRFLQESRNGG----------AIDMLPKLTR 179

302A1ps         SAPKSVRNFIPQVDGVTREFLTFLRESSDDGD---------AIDMLPKLTR 180

314a1m          TSPRVLQNFLPALNAVCDDFIELLRARRDPD-----------TLVVPNFEE 217

314a1ps         TSPRVLQNFLPALNAVCDDFIDLLRARRDPD-----------TLVVPNFEE 218

315a1m          LNGNLNWMDVHIESCTRRMVDQWKRRTAEAAAIPLAESGEIRSYELPLLEQ 219

315a1ps         LNGNLNWMDVHIESCTRQLVDQWRARTEEATAECDVP-GSPSYYELPNLEQ 212

6a2m            TSGKMK-FMFPTVIKVSEEFVKVITEQVPAAQN----------GAVLEIKE 177

6a2ps           TSGKMK-LMFPTVIKVSEEFASVMEEQVPPTQG----------GAIIEIKE 177

6a8m            TSGKMK-LMYPTVVSVANEFMTVMHEKVPKNS-------------VLEIRD 177

6a18m           TSGKMK-FMYPTVVSVAEEFMAVMHEKVSENS-------------ILDVRD 177

6a8ps           TAGKMK-FMYPTVVSVAEEFIDVMHEKMKQNS-------------VLEIRE 177

6a9m            TSGKMK-YMFPTVVKVGHEFIEVFGQAMEKSP-------------IVEVRD 176

6a21m           TSGKMK-YMFPTVVKVANEFTDVFGQNVAKSP-------------VVEVRE 176

6a21ps          TSGKMK-YMFPTVVKVSHEFTEVFGQMADKSP-------------IVEVRE 178

6a17m           TSGKMK-NMFPIVVKVGEEMDKVFRSKTAADR-----------GQVLEVVD 175

6a23m           TSGKMK-NMFPIIVKVGEEMEKIFSAKTTTGE-----------GQVLEIVD 176

6A17ps          TSGKMK-HMFPIVVKVGEEMDKVFSNKVGD-------------GKVLEIVD 174

6A23ps          TSGKMK-HMFPIVVKVGEEMDKVFSNKVGD-------------GKVLEIVD 173

6a20ps          TSGKMK-IMFPTVLEIGNEMIRVFAEKIGPQ------------P--LNVAD 174

6a20m           TSGKMK-TMFPTILTVGDELIRVFGETASAD------------SDSMEITN 186

6a19m           TSAKMK-SMFSTVLNVGDEMIRVVDEKISSS------------SQTLEVTD 176

6a22m           TSAKMK-YMFPTVCEVGEELTQVCGELADNAM-----------CGILEIGD 176

6A22ps          TSGKMK-FMFPTICEVGVDLAEVCGELAANAI-----------CGILEISD 176

6a13m           TSGKMK-FMFPNMVEVG-------EKLTQACRLQ---------VGEIEAKD 170

6A13ps          TSGKMK-FMFPTMLSVG-------EKLTQACELQ---------VGEIEAKD 170

6a14m           TSGKIK-QMSKVIVDVGLRLGDAMDKAVKEAKVE---------EGNVEIKD 187

6A14ps          TSGKIK-HMSGVVVEVGHRLAAAMDKAVSAAKVD---------DGDVEIKD 168

6a15pm          ---------------------------------------------------

6a16m           TSGKMK-YMFGTVSTVAQQLGGTFDELVGSQG------------AVLELHD 170

6A16ps          SSGNVK-CIFGTITEVARNLEESFQELVGTQG------------GVLDVHD 170

6u1m            TPANMQ-KLLVRLSQISS----RIQRDLGEKS-----------LQTINISE 172

6u1ps           TPANIN-KLLPRIVLISR----GVQRSLGKER-----------LQTLNINE 175

317a1m          EGDRMS-LLYDCLYEEAEQLLLTVNSTLMSQP-----------HSTVHIQK 184

317a1ps         ESDRMS-WLFGSLYEEAEQLLLTVTSTLMKQP-----------HSTLHIQK 184

6g1m            TSGKVK-QMYTLMQEIGKDLELALQRRGEKNS----------GSFITEIKE 181

6G1ps           TSGKVK-QMYTLMLEIAHDLEEHLKKHVQNNSNS--------GKYITEIKE 183

6w1m            TSGKIK-QMYPLMVKIGKNLQDSAERLGSGT--------------EVQVKD 174

6w1ps           TTGKIK-QMYPLMVKIGKNLEANVGREPKDS--------------IVTIKS 176

6v1m            AGAKLK-QMFSLMEEIGCDLEWYLKRLTRDLRRGDA----ERG-AIVSIKD 187

6v1ps           TGAKIK-QMFSLMEEIGCDLEYYLKRLTRDMRRSDA----SARGVIVSIKD 188

6g2m            TGNRLK-QMFPLIEEVGASLDAHLRQQPLHNER--------MRCFDLEAKE 182

6g2ps           TSNKLK-SMFPLIVEVGSNLDAYLREQPLHNER--------TRCFDLEAKE 182

6t1m            AAGKV-RNMYGLLENIGQKLEEHMEQKLSGRDS-----------MELEVKQ 198

6t2pm           --------LYGLLERIQNLEAHMKKKKLNGAES-----------VELEVKQ 179

6t1ps           AVSKV-RQMYGLLEHIGQQLEEHMEDQLNGKSE-----------IELEVKQ 202

6t3m            TSGRMRDVMYSQMLDVASDLEQYLNRKLGDRLE-----------RVLPLGR 179

6t3ps           TSGRMRESMYPLMMGVVIDLEQYLQRKLGDRSE-----------RMLPLSK 180

9b1m            TSAKMR-NMFTLMNESFAQCLEHLKSSQPIA-A-------GENAFELDMKV 180

9b2m            TAAKMR-NMFTLMNESFAECLQHLDSSSKTL-P-------GRKGFEVDMKV 180

9B2ps           TAAKMR-SMFALMNDSFGECLEHLSRLSDGS-K-------SGEGLEVDMKV 180

9f2m            TGSKMR-QMFQLMNQVAKEAVDCLKQDDS-----------RVQENELDMKD 184

9f3pm           TGSKMR-QMFQLMNQVAKEAVDCLKQDDS-----------RVQENELDMKD 184

9F2ps           TGLKMR-QMFQLMNQVAKEAVDCLKPDQQG----------SVQGTELDMKD 185

9c1m            TSLKIR-QMFELIHFCNVEAVDFVQRQLDAG------------TSELELKD 180

9c1ps           TSLKIR-LMFELIQVCNVEAVAYIERKLAEDG-----------ATELELKD 183

9h1m            TGSKMR-IMYDLIQSCSEEGVIHIQEQLELSQ---------DASIELEMKD 182

9h1ps           TGTKMR-VMYQLIQSCSEEAVRHIGEQLAQSN---------TGAIELEMKD 182

6d2m            SSGKIK-GMFGTIDDVGDKLVQHLEGALDQS-------------DEVEIKD 171

6d2ps           SSGKIK-GMFGTIDDVGDKMVQHLKGVLERAGAD----------NEIDIKE 175

6d4m            TSGKLK-SMFSTSEDIGDKMVAHLQKELPEEGF-----------KEVDIKK 175

6d4ps           TSGKLK-GMFSTSEEIANNMVNHLQKTLPEQGS-----------QEVDLKT 175

6d5m            TSGKLK-AMFETSDSVGDKLVDSIRKQLPANGA-----------KELELKK 173

6D5ps           TSGKLK-AMFSTSEAIGDKMVAHLNGKLPKEGS-----------QEIEMKE 173

310a1m          GTKRLS-EMFGQVQKVGDHLIHHLLDRQ-GQGCP----------QEVDIQQ 159

310a1ps         ATKRLS-EMFTHVQRVGDHLISYLLDIEQAQGGA----------LELDLQQ 160

28a5m           TMGRIK-TVYPVTNKVCQKLTEWVEKQLRLGSK----------DGIDA-KH 180

28A5ps          TMGRIK-TVYPVTNKVCQKLSEWVDKQIRLGAP----------EGINA-KD 180

28d1m           SANRVK-AAYPVSLRVCKKFVEYIRRQSLMAPA----------QGLNA-KD 182

28d1ps          SANRVK-AVYPVSQSVCKHFVEYIKRQQRMATS----------DGINA-KD 182

28d2m           SPNRVK-AVYPVSQSVCKKFVEYIRRQQQMATS----------EGLDA-MD 182

28c1m           TNGRIR-TTHAIMQRVCLDLCQFIAIKSAGG------------KDLDC-ID 178

28c1ps          TNGRIR-TTHTIMQRVCRDLCDFIAKESLKG------------EPQDG-MD 178

309a1m          TPSRLK-MAYSIWEQSGRKLVEYIERARREQGD----------IIETR--D 184

309a1ps         TPNKLK-MAFTIWEQSGKKLLEYIERVRQERGD----------IIETR--D 184

309a2m          SGSRLR-QAYNIWEQGGQMLTEYMTQQVAEKNN----------ILETR--D 183

309a2ps         SGHRLK-QGYAIWEEGGRMLTSYMTDRIKAPHN----------LLETR--D 183

308a1m          TPSRVR-QTLPHVARACQLLRDQVP------------------LGRFEAKD 169

308a1ps         TPSRLR-QTLPHVAAACQQLQEFVGRRLT--------------GERFEAKA 179

4aa1m           HHNLLEKFIDTFVDASQSLYENLDAEAVG---------------TEINIAK 188

4aa1ps          HLSLLEKFIGTFVDASQSLYESVGASAVG---------------TDINIVS 199

4C3m            HFKILDDFIDVFNEQSAVLARKLAVEVGS---------------EAFNLFP 198

4C3ps           HFKILDDFVDVFNEQSAVLARKLAVEVGS---------------EAFNLFP 198

4d1m            HFKILDQFVEVFEKGSRDLLRNMEQDRLKHG------------DSGFSLYD 177

4D1ps           HFKILDQFVDVFENGSRDLLRNMEMDRLRQG------------QTGFNLYD 177

4d1malt         HFRILEPYVEIFDRQSLRLVEELALRISR-G------------QERINLGE 168

4D1psalt        HFRILEQYVEIFDRQTHQFLSNLDLARGK-D------------DNLVNLGH 178

4s3m            HFRILSEFKEPMEENCRILVRRLRTKANG---------------ESFDIYP 167

4s3ps           HFRILSEFKEPMEENCRILVSQLKERANG---------------EAFDIYP 167

312a1m          NYTMIKQFVAVFEKQSRILLTNVAKFAES--------------GDQIDFLQ 175

312a1ps         NYTMIKQFVQVFERQSRILLPRVAEYAES--------------GKSVDFLD 176

4g1m            HQSILKSFVPTFVDHSKAVVARMGLEAGK----------------SFDVHD 194

4G1ps           HQSILKSFVPTFVDHSKSVVGRMGLETGK----------------SFDVHD 192

4g15m           HLNVLKSFIELFNENSRNVVRKLRAEDGR----------------TFDCHD 182

4G15ps          HLNVLKSFIELFNENSRNVVRKLRAEDGR----------------TFDCHD 182

4d2m            HFKILEQFVEIFDQQSAVMVEQLQSRADG--------------MTPINIFP 170

4D2ps           HFKILEQFVEIFDQQSAVMVGQLQQRADG--------------KTAINIFS 171

4d14m           HFKILEDFVEVFDQQSATMVQKLYDRADG--------------KTVINMFP 172

4d14ps          HFKILEQFVEVFDQQSAIMAKNLYDRADG--------------KTVINMFP 172

4d8m            HFSILEQFVEVFDQQSNICVQRLAQKAN---------------GNTFDVYR 169

4d8ps           HFSILEQFVEVFDQQSNVCVERLAPRAN---------------GQTFDVYR 169

4ae1m           HFSILEQFVEVFDRQSSILVERLRTLSYG--------------NEVVNIYP 173

4AE1ps          HFSILEEFVEVFDKQSQLLVERLQPLSNGG-------------MVAINIYP 174

4d20m           HFKVLEHYVEIMDRHSSVMVDNLRKVADG--------------KTAVDMLK 172

4D20ps          HFNVLGHYVDIMDRQAAVMVEKLRQVADG--------------ETTVDMLP 173

4d21m           HFKCLENFVEIMDRNSGIMVEKLKNYADG--------------KTCVDLFK 172

4e2m            HFNILQDFHEVMNENSTKFIKHLKTVAAG--------------DNIFDFQE 172

4e2ps           HFNILQDFHEVMNENSTKFIKQLKQVAAG--------------DSIFDFQN 172

4e1m            HFNILQDFHEVMNENSTKFIDQLKKVADG--------------GNIFDFQE 172

4e1ps           HFNVLQDFHEVMNEKSTKFIKHLKNVSGG--------------GSIVDFQE 172

4e3m            HFNILQDFHEVMNENSAKFMTQLKKASAG--------------DTIIDFQE 172

4e3ps           HFNILQDFHEVMNENSTKFIAQLRRDAAG--------------DSIIDFQD 172

4ad1m           ERSAIEGYLRVVHRTGGQFVQKLDVLSDT--------------QEVFDAQE 174

4AD1ps          ERSAIEGYLRVVHRTGGKFVQKLNELTET--------------LEVFDAQE 174

4p1m            HFNILNQFQEIFKTESQKFLLQFEGQDEV---------------TITLH-D 183

4p3m            HFNILNQFQEIFITESLKFLEQFKGNDEA---------------IISLN-E 183

4p1ps           HFNILGQFQEIFRAESLKFVQQFQSQDES---------------IVSLS-D 183

4P2ps           HFNILEQFQEIFQAESLKFVQQFQSQDES---------------IVSLS-D 185

4P3ps           HFNILGQFQEIFQAESLKFVQQFQSQDEN---------------IVSLS-E 184

4p2m            HLDILNQFQEIFIAESLKFVSQFQGQNEV---------------VVSLK-D 185

4ac1m           HFNVLQSFLGIFKEECKKFLNVLEKNLDA---------------ELELN-Q 185

4AC1ps          HFNVLQSFLAIFKEECNKLIKVLDKKVDG---------------ELDLN-Q 185

4ac2ps          HFNVLQSFLAIFKEECHKLVKVLHESVES---------------EALVLNQ 186

4ac2m           HFKVLQSFLIIFKEECNKLVKVLHQSVNM---------------ELELN-Q 186

4ac3m           HFNILQSFLSIFKEESKKFIKILDKNVGF---------------ELELN-Q 185

311a1m          QPQLLRSFAPAIGGHVERLVGRLGATRG----------------AFLEVTE 165

311a1ps         RPTLLRSFAPSVAKHADRLIQRLEETRG----------------SFLEVTD 114

316a1m          DKGNLEQLIDLSRHQTEQLLQKLAKQADQK---------------VFDIWY 167

316A1ps         NKGNMLPLTELCRQQAVLLQLTLADHAEQRD--------------VFDAWT 168

313a2m          KHSVLLSFLPIFNAETDLLVSVFDSFVGQG---------------EKDVLS 170

313a3m          KQNVLLSFLPIFNSEAKTLVAFLDSLVGQG---------------EKKVRD 170

313a1m          KQDLLLSFFHIFDAETKVLMNLLDTYVDKG---------------EIDVVP 170

313C1ps         RHNVLMSFFPLFNEETKNLISLLETFVGQG---------------EKKLLP 169

313C2ps         KKNVVMSFLPIFNEETNSLLSVLDTFVGQG---------------EREILP 169

313a5m          KNNAVLSFVPVLNNEANFLVTLLAEFVDGG---------------DINLLP 169

313a4m          GHKVLLSFLPIFNRETALLLDQLEPLQDDG---------------EKDLIP 168

313a4ps         GHKVLLSFLPIFNKETAQLLSQLDALPGGG---------------EKDLIP 168

313A4bps        SHKVLLSFLPIFNKETGQLLSQFDDLPSKG---------------EYNLIP 168

313b1m          GRQILSNFLPIFNAEAEVLLQKLELEGVQHG-------------KRLEIYQ 170

313b1ps         GRQILCNFLPIFNAEAEVLLLKLDLEGVQHG-------------KELEIYQ 172

318a1m          SHNIVASFFDVFNSVGNQMVEQFQTQTNLHGQA----------VKFTAAED 175

318A1ps         SHNIVASFFDVFNAVGNQMVEQFASQPHLHGRA----------VKFTDAED 175

18a1m           RQFGMTYMGN--------GKQQMQKRIMTEVHEFIG-HLHASDGQPVDMSP 193

18a1ps          RQFGMTYMGN--------GKQQMQKRIMTEVHEFIG-HLHASDGQPIDLSP 194

306A1m          KALGMTRRPGELRARLERRIARGVDECVRLFDT----EAKKSCASEVNPLP 195

306A1ps         KALGMTRRPGETRSRLEQRIGRGVDECVQLYET----DADVSPSSEFDPVP 200

303a1m          KNFGFAR--SGMMDIVHNEATCLLQDLKDKVLK------SGGKQTRIEMHD 180

303A1ps         KNFGFAR--SGMTDIVHNEATCLLQDLRAVVRR------EGGHQARIQMHD 180

305a1m          RNVGYGR--SQMEHHIELEAEELLGQLERTE------------EQPIEPVT 174

305A1ps         RHVGYGR--SQMESHIEREAEELLLQLGRTE------------EAPIEPVT 174

304a1m          RDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGGYRVLLPL 187

304a1ps         RDFGFGRRFDELELVIKEQITDMLDMIRNGPKYPHEHHLVKPGGYRVQLPL 187

307a1m          RRHCSPREFSCFYMKMSQIGCEEMEHWNRELGN------QLVPGEPINIKP 203

307a1ps         RRHCSPRESSSFYMQMSQIGCEEMEHFIREIDA------KMVPGEPFDVKT 198

307a2pm         ---------------------------------------------------

307a2pps        RRHCSPRESSPYFNKMSHIGCNEINHLMREL-N------KTQPGKPFDIKK 198

 

                6A 6B   6C 6D                         6E

12a4m           TINRWTLESVSVVALDKQLGLLKNS--NKESEALKLFHYLDEFFIVSIDLEMKPSPWRYI 264

12a5m           TINRWTLESVSVVALDKQLGLLRES--GKNSEATKLFKYLDEFFLHSADLEMKPSLWRYF 264

12A4ps          IINRWTLESVSVVALDKQLGLLKES--GDNDLAVLLFKHLDDFFELSADLEIKPSIWRYV 263

12A5ps          VINRWTLESVSVVALDKQLGLLKES--DDNDQAVLLFKYLDDFFELTADLEMKPSIWRYF 263

12c1m           TINHLTFESVATVALDRELGLLREA--NPPPEASKLFKNIEVLMDSFFDLGVRPSLYRYI 256

12c1ps          TINTLTFESVAVVALDRELGLLRDS--DQKPEAKELFRNIKIFLQSFFDLGIKPSVYKYI 266

12e1m           DIRHLVIESICSVALNTHLGLLGEQ--RNNKDIQKLVLALQDVVELGFQLDIMPAFWKYL 246

12e1ps          DIRNLVIESIGSVALNTHLGLLGEN--RYSDEANQLKAAMRDFVELGFQLDMMPAIWKYL 248

12d1m           EISRLVFESLGLVAFDRQMGLIRKN--RDNSDALTLFQTSRDIFRLTFKLDIQPSMWKII 258

12d1ps          EMQRLIFESLALVSFDRQMGIIRKH--RDNPDALALFRTSRDIFRYTFQLDVQPSAWKIV 258

12b2m           QLKMWAFESISFVALNTRMGLLSDN---PDPNADRLAKHMRDFFNYSFQFDVQPSIWTFY 268

12B2ps          QLKNWAFESISFVALNTRMGLLSDQ---PDPNAARLAKHMSDFVNYSFQYDVLPSIWPYY 271

49A1m           ELYKWALESVGRVSLDTRLGCLSP--E-GSEEAQQIIEAINTFFWAVPELELRMPLWRIY 318

49A1ps          ELYKWALESVGRVSLDTRLGCLSP--E-GSEEAQQIIDAINTFFWAVPELELRMPLWRIY 323

301a1m          EIHKWSLECIGRVALDTRLGCLESNLK-PDSEPQQIIDAAKYALRNVATLELKAPYWRYF 292

301A1ps         EIHKWSLECIGRVALDTRLGCLEANLS-PDSEPQQIIDAAKYALRNVATLELKAPYWRYF 297

302a1m          LN----LELTCLLTFGARLQSFTAQEQDPRSRSTRLMDAAETTNSCILPTDQGLQLWRFL 235

302A1ps         LN----LELTCLLTFGARLQSFSPEEQSPQSRSTHLMHAAETTNSCILPTDQGLQLWRLM 236

314a1m          LANLMGLEAVCTLMLGRRMGFLAIDTKQPQ-KISQLAAAVKQLFISQRDSYYGLGLWKYF 276

314a1ps         LANLMGLEAVCTLMLGRRMGFLAADAKQPQ-KISQLAAAVKQLFISQRDSYYGLGLWKYF 277

315a1m          QLYRWSIEVLCCIMFGTSVLTCPK---IQSSLDYFTQIVHKVFEHSSRLMTFPPRLAQIL 276

315a1ps         QLYRWSIEVLCCIMFGSNVLTCPK---IQSALDHFTQIVHKVFEHSSRLMTFPPRLAQLL 269

6a2m            LMARFTTDVIGTCAFGIECNT-LRT------PVSDFRTMGQKVFTDMRHG-KLLTMFVFS 229

6a2ps           MMARFTTDVIGTCAFGIECNT-LRT------PVTDFRTMGQKAFTELRHG-QLLTFFIFS 229

6a8m            LVARFTVDVIGTCAFGIQCNS-LRD------EKAEFLYFGKRSLVDKRHG-TLLNGFMRS 229

6a18m           LVARFTVDVIGTCAFGIKCNS-LRD------EKAEFLHFGRRALLDSRHG-NLVSGLMRS 229

6a8ps           LMARFTVDVIGTCAFGIKCNS-LRD------ENAEFLRFGKRTFVDKRHG-SFLTGFMTS 229

6a9m            ILARFTTDVIGTCAFGIECSS-LKD------PEAEFRVMGRRAIFEQRHG-PIGIAFINS 228

6a21m           LLARFTTDVIGTCAFGIECSS-LKD------PDAEFREMGRRSLTEQRLG-PVGIGFVNS 228

6a21ps          LLARFTTDVIGTCAFGIDCSS-LKD------PDAEFRKMGRRALTENRHG-SLGIAFLNS 230

6a17m           LVARYTADVIGNCAFGLNCNS-LYD------PKAEFVSIGKRAITEHRYG-NMLDIFLFG 227

6a23m           LVARYTADVIGNCAFGLNCNS-LQN------PNAEFVTIGKRAIIERRYG-GLLDFLIFG 228

6A17ps          LVARYTADVIGNCAFGLNCNS-QQN------PNADFVTFGKRALRERRYK-GLLDFFIFG 226

6A23ps          LVARYTADVIGNCAFGLNCNS-QQN------PNADFVTFGKRAIGERRYW-GLLDFFIFG 225

6a20ps          LVSRFSADVIGSCAFGLECNS-LRN------PNAEFVTMGKAAITERRYG-KTADLFFFG 226

6a20m           VVARFTADVIGSCAFGLDCHS-LSD------PKAKFVQMGTTAITERRHG-KSMDLLLFG 238

6a19m           IVSRFTSDVIGICAFGLKCNS-LRD------PKAEFVQMGYSALRERRHG-WLVDLLIFG 228

6a22m           LMARYTSDVIGRCAFGVECNG-LRN------PEAEFAIMGRRAFSERRHC-KLVDGFIES 228

6A22ps          IMGRYTSDVIGRCVFGLECNG-LRN------PEAQFAVMGRRAFTERRHN-QLIDGFIES 228

6a13m           LCARFTTDVIGSCAFGLECNS-LQD------PESQFRRMGRSVTQEPLHS-VLVQAFMFA 222

6A13ps          LCARFSTDVIGSCAFGLECNS-LND------PNSEFRRMGRSVTTNPLHT-GMVQGFMFA 222

6a14m           LCARFTTDVIGSCAFGLECNS-LQD------PSAEFRQKGREIFTRRRHS-TLVQSFIFT 239

6A14ps          ICARFTTDVIGTCAFGLECHS-LSD------PKAEFRSKGRMIFEKPRHS-PIVQFFVFT 220

6a15pm          -------------------------------------------------------AFTVT 5

6a16m           LMARYTTDVIGSCAFGTECSS-LRE------PQAEFRQVGRRIFRNSNRS-IRWRIFKMT 222

6A16ps          LLDRFSMDASATCAFGIQCSS-LKD------PQVEFRVHGRKIFHHSGDG-IRWRIFKFL 222

6u1m            LVGAYNTDVMASMAFGLVG-------------QDNVEFAKWTRNYWADFR-MWQAYLALE 218

6u1ps           LVDSYNLDVVASMAFGLS--------------ADRTEFRRWTQSYWGKFS-LWRAYLALE 220

317a1m          IMRRYVLSSLAKCVFGLNAEQRKTY------PLEDFEQMTELALNSHKHG-YLMNLMMIR 237

317a1ps         LMRRYVLSALAKCVFGLDAQQRLKY------SLEDFEKMTEMAVSSHKHG-YLMNLMMIR 237

6g1m            ICAQFSTDSIATIAFGIRANS-LEN------PNAEFRNYGRKMFTFTVAR-AKDFFVAFF 233

6G1ps           VCAQFSTDSIATIAFGIRANS-LQN------PNAEFRNHGRKLFSFTLSR-AKDFFVAFF 235

6w1m            LCSRFTTDLIATIAFGVEANA-LQD------AKSEFFYHNRAIFSLTLSR-GIDFAIIFM 226

6w1ps           LCARFTTDLIATIAFGLDANA-LQD------PKSEFFRHNQAIFAPSVSR-AIDFAIIFM 228

6v1m            VCDLYNTDMIASIAFGLRSYS-LRN------TQSEIGSHCQDLFRPNVRR-IIDLFVIFY 239

6v1ps           VCDLYNTDMIASIAFGLRSYS-LRS------TQSEIGSHCQDIFRPNVRR-IIDFFVIFY 240

6g2m            LCALYTTDVIATVAYGVSANS-FTD------PKCEFRRHGRSVFEFNLLR-AAEFTLVFF 234

6g2ps           LCALFTTDVIASVAYGVQANS-FTQ------PNGEFRRHGRAVFEFSLKR-AAEFTLVFF 234

6t1m            LCALFTTDIIASLAFGIEAHS-LQN------PEAEFRRMCIEVNDPRPKR-LLHLFTMFF 250

6t2pm           LCALFTTDILQ------SLQ----N------PEAEFRPMCIEVNDPKPK----RLS---- 215

6t1ps           LCALFTTDIIASLAFGLEAHS-LQK------PDAEFRRMCVEVNDPRPKR-LLHLFTMFF 254

6t3m            MCQLYTTDVTGNLFYSLNVGG-LRR------GRSELITKTKELFNTNPRK-VLDFMSVFF 231

6t3ps           MCQLYTTDVTGNLFYSMDVGG-LRR------GKSQLLKKTKELFDPDPRK-VLDFMSIFF 232

9b1m            LCNKLSNDVIATTAFGLKVNS-FDD------PENEFHTIGKTLAFSRGLP-FLKFMMCLL 232

9b2m            MCNKLSNDIIATTAFGLKVNS-YDN------PKNEFYEIGQSLVFSRGLQ-FFKFMLSTL 232

9B2ps           LCNKLSNDLIATTAFGLKVNS-FES------PDNEFYQIGQSLTFSRGSQ-LFKFLLATL 232

9f2m            YCTRFTNDVIASTAFGLQVNS-FKD------RENTFYQMGKKLTTFTFLQ-SMKFMLFFA 236

9f3pm           YCTRFTNDVIASTAFGLQVNS-FKD------RENTFYQMGKKLTTFTFLQ-NMKFILLFA 236

9F2ps           YCTRFTNDVIASTAFGLQVNS-FKE------RDNDFYSMGKKLTTFGFLQ-NLKFMLFFT 237

9c1m            FFTRYTNDVIATAAFGIQVNS-FKD------PNNEFFSIGQRISEFTFWG-GLKVMLYIL 232

9c1ps           FFTRYTNDVIATAAFGIQVNS-FKD------PNNEFFSIGQRISDFSLWA-VLKVMLFIL 235

9h1m            YFTRFANDVIATVAFGISINS-FRR------KDNEFFRIGQAMSRISAWS-VVKAMLYAL 234

9h1ps           YFTRFANDVIATVAFGLSVNS-FRR------KDNEFFRIGQALSKISVWS-IVKAVLHAL 234

6d2m            VMTTYAVDIIGSVIFGLEIDS-FRN------PKNEFREISSSTSRDESLLLKIHNMSMFI 224

6d2ps           MMTTYAVDIIGSVIFGLEIDS-FAN------PNNEFRAISNEEARSKSLLLKIHNMAMFI 228

6d4m            VMQNYAIDIIASTIFGLDVNS-FEN------PDNKFRKLVSLARAN-NRFNAMFGMMIFL 227

6d4ps           VMQTYAIDIIASTIFGLEMNS-YLT------PDNKFRNLVTIARRN-TRFTTMFGMMIFL 227

6d5m            LMATYAIDIIATTIFGLDVDS-FAD------PNNEFQIISKKVNRN-NIEDIIRGTSSFL 225

6D5ps           LLLTYAVDIIASTIFGLDVDS-FAD------PNNEFLSITKTINQN-TFTDILRGTTSFL 225

310a1m          KLRVYSVNIIANLIYGLDINN-FEH------------------EDH-ILTSYLSHSQASI 198

310a1ps         MLRVYAINVIGNLIYGLDVNN-FEQ------------------KDH-ILSSYVSAGHTSL 199

28a5m           MSLCFTTEMVTDCVLGLGAESFS--------DKPTPIMSKINDLFNQPWTFVLFFILTSS 232

28A5ps          MSLCFTSEMVTDCVLGLSAESFS--------DNPTPIMGHIKDLFSQSWSFLIYFVIIST 232

28d1m           LCLCYTTEVISDCVLGISAQSFT--------DNPTPMVGMTKRVFEQSFGFIFYTVVANL 234

28d1ps          LCLCYTTEVVSDCVLGISAQSFT--------ETPTPLVGMIKRVFEQSFGFIFYTMAANL 234

28d2m           LSLCYTTEVVSDCGLGVSAQSFT--------DTPTPLLKMIKRVFNTSFEFIFYSVVTNL 234

28c1m           LGLRFTGESLFDCVLGIQARTFT--------DNPLPVVRQNHEMSAENRGLAIAGAVHGL 230

28c1ps          LGLRFTGDSLFDCVLGIQARCFS--------DSPLPVIRHNREMSNENPGLAIAGALNGL 230

309a1m          LAYRFTANAMADFIWGIDAGSLSGKV-----GEIGDFQKTSTDWSAHAFSSMIRFNKTLV 239

309a1ps         LAYRFTANTMADFIWGIDAGTLTGAV-----GETSPFQKTSTDWTINAFKSIIRFNKSLV 239

309a2m          LCFRYTAHVMADFIWGIDAGTLTRPM-----EQPNKVQEMASKWTSYAFYMLTLFMATIV 238

309a2ps         LCFRYTAHVMADFIWGIDAGTLSRPQ-----EHPNKVQQMASKWTSHAFYMISVFMASIV 240

308a1m          LATRYTLQVVASAIFGLDAHCLGIHM--RVAHEPSRWLEWLAPLFQPSVWSLLETMSLLH 227

308a1ps         LATRYTLQVIASAVFGLDAHCLCYDE---DQEKGSQWLQRLLPLFQPSAWSLLETIALLH 236

4aa1m           YVNNCVLDILNEAVLGVPIKKRGQD---VAMMEDSPFRQGKIMMPARFTQPWLLLDGIYH 245

4aa1ps          IVNNCVVDILNEAVLGVPIKKKGLD---LVKIDESPFRQGKLMIPTRFSHPWLLFDGIYH 256

4C3m            YVTLCTLDIVCETAMGRRIYAQSN----SESEYVKAVYGIGSIVQSRQAKIWLQSDFIFS 254

4C3ps           YVTLCTLDIVCETAMGRRIYAQSD----SESEYVKAVYGIGSIVQSRQSKIWLQSDLIFR 254

4d1m            WINLCTMDTICETAMGVSINAQSN----ADSEYVQAVKTISMVLHKRMFNILYRFDLTYM 233

4D1ps           WINLCTMDTICETAMGVSINAQTN----ADSEYVQAVKTISMVLHKRMFNIFYRFDLTYM 233

4d1malt         AIHLCALDAICETAMGVSINAQSN----ADSEYVQAVKTISMVLHKRMFNILYRFDLTYM 224

4D1psalt        AVHLCALDVICETAMGVSINAQTN----ADSEYVQAVKTISMVLHKRMFNIFYRFDLTYM 234

4s3m            YITLFALDAICETAMGIKKHAQLQ----SDSEYVQAVQSICRVMHKQSFSFWQRLNVFFK 223

4s3ps           YITLFALDAICETAMGIKKHAQLQ----SESEYVKAVQTICRVMHKQSFSFWQRLNIFFK 223

312a1m          LISCFTLDTICETALGVSVGSQSS----AKSEYLDAVKSILVIIDKRLKNIFYRNSFIFK 231

312a1ps         LISCYTLDVICETALGVSVDAQSG----KRSSYLEAVREVLHVIDYRLKNLFYRHSFIYR 232

4g1m            YMSQTTVDILLSTAMGVKKLPEGN----KSFEYAQAVVDMCDIIHKRQVKLLYRLDSIYK 250

4G1ps           YMSTTTVDILLSTAMGVKKLPEGN----KSFEYAQAVVDMCDIIHKRQVKLLYRLDSIYK 248

4g15m           YMSEATVEILLETAMGVSKKTQDK----SGFEYAMAVMRMCDILHARHRSIFLRNEFVFT 238

4G15ps          YMSEATVEILLETAMGVSKKTQDK----SGFEYAMAVMRMCDILHARHRSIFLRNEFVFT 238

4d2m            VICLTALDIIAETAMGTKINAQKN----PNLPYVQAVNDVTNILIKRFIHAWQRVDWIFR 226

4D2ps           VVCLLALDIIAETAMGTKIQAQMS----PNLPYVQAVTDVTNIMTTRFIHAWQRIDWLFR 227

4d14m           VACLCAMDIIAETAMGVKINAQLQ----PQFTYVQSVTTASAMLAERFMNPLQRLDFTMK 228

4d14ps          VACLCAMDIIAETAMGVKINAQLQ----PNFPYVQSVKTASGMLAERFVNPAQRLDISMR 228

4d8m            SICAAALDIIAETAMGTKIYAQAN----ESTPYAEAVNECTALLSWRFMSVYLQVELLFT 225

4d8ps           PVCMAALDIIAETAMGTKIHAQAA----ESTPYAEAVNECTALLSWRFISVYLQVELLFT 225

4ae1m           LVGLAALDIITETAMGVNVDAQG-----ADSEVVHAVKDLTNILATRFMRPHLLFPHLFR 228

4AE1ps          YVGLAALDIITETAMGVCVNAQLD----ADSAVVQAVKAVTNTLATRFMRPHLLPPLLFR 230

4d20m           YVSLAALDVITEAAMGVQVNAQND----PDFPYIKALKSVVYIQPDRMFRFSRRYNWLFP 228

4D20ps          YVSLAALDVITEAAMGVQVNAQSD----SEFPYVQALKSVVYIQSDRMFRFLQRYDWLFR 229

4d21m           FVSLEALDVTTETAMGVQVNAQNE----PNFPYTKALKSVVYIESKRLASVSMRYNWLFP 228

4e2m            QAHYLTLDVICDTAMGVSINAMEN----RSSSIVQAFKDMCYNINMRAFHPLKRNELLYR 228

4e2ps           ETHYLTLDVICDTAMGVSVNAMEN----RSSSIVQAFKDMCYCINMRAFHPFKRNDLFFR 228

4e1m            EAHYLTLDVICDTAMGVSINAMEN----RSSSVVQAFKDITYTIKMRAFSPWKRNKYLFH 228

4e1ps           QAHFLTLDIICETAMGVSINAMEN----QDSELVQAFKDMCYNIKVRTFSSWKRNPTLYQ 228

4e3m            HANYLTLDVICDTAMGVPINAMEQ----RDSSIVQAFRDMCYNINMRAFHPFKRSNRVFS 228

4e3ps           HAHYLTLDVICDTAMGVPINAMEH----RNSAIVQAFKDMCLSVNMRAFHPFKRSNRIYS 228

4ad1m           LVAKCTLDIVCENATGQDSSSLNG----ETSDLHGAIKDLCDVVQERTFSIVKRFDALFR 230

4AD1ps          LVAKCTLDIVCENATGLVSNSLND----EPSDLHGAIKDLCDVVQERTFSIVKRFDALFR 230

4p1m            VIPRFTLNSICETAMGVKLDEMAE----KGDRYRENFSQIEECFIRRLSNPLLWGDKLFE 239

4p3m            VIPRFTLNSICETAMGVKLDEMAE----KGDRYRENFRQIEECFIRRMSNPLLWSDTLFK 239

4p1ps           LIPRFTLNSICETAMGVKLDEMAE----KGDRYREGIHMIEMSFIRRLSNPLLWNKTIYN 239

4P2ps           LIPRFTLNSICETAMGVKLDEMAE----KGDRYREGIHMIEMSFIRRLSNPLLWNKTIYN 241

4P3ps           LIPRFTLNTICETAMGVKLDEMAD----KGDRYRESFHMIEKSFVRRLSNPFLRSTTIYN 240

4p2m            RISRFTLNSICETAMGIKLDEMAE----KGDRYRANFHIIDEGLTRRIVNPLYWDDCVYN 241

4ac1m           VIPPFTLNNICETALGVKLDDMSE-----GNEYRKAIHAIEEVLIQRVCNPLMYYNWYFF 240

4AC1ps          VIPQFTLNNICETALGVKLDDMSE-----GNQYRRAIHAIEEVLIQRVCNPLMFYNWYFF 240

4ac2ps          VIPQFTLNNICETALGVKLDDMAE-----GFQYRESIHAIEAVILQRICNPFLYNSLYFY 241

4ac2m           VIPQFTLNNVCETALGVKLDDLSE-----GIRYRQSIHAIEEVMQQRLCNPFFYNIVYFF 241

4ac3m           IIPQFTLNNICETALGVKLDDMSE-----GNEYRKAIHDFEIVFNQRMCNPLMFFNWYFF 240

311a1m          PLFACLLDAIVDTSMGAQLDTQSV----DHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQ 221

311a1ps         PLFACLLDAIVDTSMGEQLETQSV----AHSPIIKAFHRSSQLLFKRMINPLLASDWVFK 170

316a1m          TVSPIVLDLMVMTTCGAKPSEEYS----------KNLKDLSEIYRKRFLSLQSANRFNYW 217

316A1ps         IVAPAVRDLMVLTTCGVRPSEGYS----------EAFTCLTEIYRKRFLSLQSVNRFTFW 218

313a2m          DLIRWSFAIATQTTLGTDVTKDDNF---ENDAILKTYQSMLRLTIINIFVPFVQNKIVSK 227

313a3m          DIVRWSFRIATQTTVGTDVKKDASF---KNDSVLKSYETFMKIIVMNVLLPFTHNKIFST 227

313a1m          EMLRWSFKIAAQTTMGSEVKHDEHF---KNGSLVESFESLISHSTLNILMPLVQNRMISK 227

313C1ps         EFINWSFRTSIQSTMGSDLKDNPSI---MNGAIQKKISNLIEVTYYLITFPWLQNRAIST 226

313C2ps         NVLNWSFRTAYQTTLGSDVKANTSF---KNGTLLKNFKYTMENTTLAILFPLVQNRIIAK 226

313a5m          ELNKWSFKIAAQITMGDEVRNQANY---QNGNLLESYKALNNLIPIGVVMPWLRNKYLGK 226

313a4m          LLQSFTLGIATQTTMGSDVKDEESF---RSNSLLGRYQCILETMTDMCFSPWLNSRFCRQ 225

313a4ps         LLQSLTLGIATQTTMGCDVKSEENF---MSNSLMERYQCCLETMTDMCFSPWLNSRWARQ 225

313A4bps        LLQNFTMGITTQTTMGLDVKSEANF---N--SIVESYHCCLETITDMCISPWLHFKWVRQ 223

313b1m          ILKKIVLEAACQTTMGKKMNFQHDG---S-LCIFKAYNGLTEVCVKRMLSPWLYPDLIYR 226

313b1ps         ILKKIVLEAACQTTMGRKMNFQQDG---S-AAIFEAYNGLTEVCVKRMLSPWLP-ELIYR 227

318a1m          LLSRAVLEVSCLTIMGTPTNFTQLD---D-AHIAHSYKRLLEISAVRVVKPWLQIRLLHR 231

318A1ps         MLSRAVLEVSCLTVMGTPTNFTQTD---D-AHIASSYKRLLEISAIRVVKPWLQIDLLHR 231

18a1m           VISVAVSNVICSLMMSTRFS--IDD-----PKFRRFNFLIEEGMRLFGEIHTVDYIPTMQ 246

18a1ps          VISVAVSNVICSLMMSTRFS--IDD-----PKFRRFNFLIEEGMRLFGEIHTVDYIPTMQ 247

306A1m          ALHHSLGNIINDLVFGITYK--RDD-----PDWLYLQRLQEEGVKLIGVSGVVNFLPWLR 248

306A1ps         ALQHTLGNIINDLVFGVTYE--RQD-----PDWLYLQRLQEEGVKLIGVSGVVNFLPWLR 253

303a1m          LTSVYVLNTLWCMLSGRRYE-PGSP-----EITQLLETFFELFKNIDMVGALFSHFPLLR 234

303A1ps         LTSVYVLNTLWCMLSGQRYD-PGSV-----EITELLETFFELFKNIDMVGALFSHFPLLR 234

305a1m          WLAQSVLNVLWCLIAGKRIARQEDG-----TLRRLLDLMNRRSKLFDICGGLLAQFPWLR 229

305A1ps         WLAHGVLNVLWCLIAGKRIASEGNS-----MLQRLLDLMNRRSKLFDVCGGLLAQFPWLR 229

304a1m          LFNPFSANAHFYIVYNECLSREEMG-----KLVKLCQMGIQFQRNADDYGKMLSIIPWIR 242

304a1ps         LFNPFSVNSHFHVVYNERQSREDMA-----GLVRLVQMGMQFQRHADDYGRLLSIMPWIR 242

307a1m          LILKACANMFSQYMCSLRFD--YDD-----VDFQQIVQYFDEIFWEINQGHPLDFLPWLY 256

307a1ps         FLLRACANMFSQYMCSQRFD--YDD-----EEFHKIVQYFDEIFWEINQGHPLDFLPWLY 251

307a2pm         ------------------------------------------------------------ 145

307a2pps        LILGASANMFCQYMCSIRFD--YND-----KEFRRIVRYFDEIFWEINQGYSLDFLPWML 251

 

                  7A 7B   7C    7D      7E

12a4m           KTPKLKRLMRAL---DGIQEVTLAYVDEAIERLDKEAK------------------------- 299

12a5m           KTPLLKKMLRTM---DSVQEVTLKYVDEAIERLEKEAK------------------------- 299

12A4ps          KTPKLMKLMKAL---DGVQEVTLAYVDEAIERLEKEAK------------------------- 298

12A5ps          KTPKLMKLMKAL---DGVQEVTLAYVDEAIERLEKEAK------------------------- 298

12c1m           PTPTYKKFSRAM---DEIFDTCSMYVNQAIERIDRKSS------------------------- 291

12c1ps          STPTYRKFSQAS---DAIFDTCSMYVNEAVARIDGQS-------------------------- 300

12e1m           PMPNFKKLMRSL---DTITDFCYFHIGNALKRIEEDAK------------------------- 281

12e1ps          PVPKFNQLMRSL---DTMTDFCVTHIEQALQRIEEDVK------------------------- 283

12d1m           STPTYRKMKRTL---NDSLNVAQKMLKENQDALEKRRQ------------------------- 293

12d1ps          STPTYRKMMRTL---NESLDVAQRVLAESQQLLEHRRR------------------------- 293

12b2m           KTAGFKKFLKTY---DNITDITSNYIETAMRGFGKND-------------------------- 302

12B2ps          KTRGFNRFLKTY---DDITEITTNYIEEAIQRFKIDD-------------------------- 305

49A1m           PTKAYRSFVKAL---DQFTAICMKNIGKTMDKADADEA------------------------- 353

49A1ps          PTKAYRSFVRAL---DQFTAICMKNIGQTMDKAEADEA------------------------- 358

301a1m          PTPLWTRYVKNM---NFFVGVCMKYIQSATERLKTQDP------------------------- 327

301A1ps         PTPLWTQYVKNM---NFFVGVCMKYIQSATERLKTQDP------------------------- 332

302a1m          ETPSFRKLSQAQ---SYMESVALELVEEN---------------------------------- 261

302A1ps         ETPSYRKLRQAQ---SYMESVALKLMES----------------------------------- 261

314a1m          PTKTYRDFARAE---DLIYDVISEIIDHELEELKKSAAC------------------------ 312

314a1ps         PTKTYRDFARAE---DLIYDVISEIIDNELEEHKKSAEC------------------------ 313

315a1m          RLPIWRDFEANV---DEVLREGAAIIDHCIR---------V---------------------- 305

315a1ps         RLRIWRDFESNV---NEVLREGAAIIDHCIGGEITEDGQLE---------------------- 307

6a2m            FPKLASRLRM-----RMMPEDVHQFFMRLVNDTIALRE------------------------- 262

6a2ps           FPKLARRLRM-----RIMPEDVHQFFMRLVNDTVAVRE------------------------- 262

6a8m            YPKLARKLGM-----VRTAPHIQEFYSRIVTETVAVRE------------------------- 262

6a18m           YPNLARRLGL-----CRNTAQIQEFYQRIVKETVTLRE------------------------- 262

6a8ps           YPKLARRLRL-----VRTPTHIRNFYERIVHETVAMRE------------------------- 262

6a9m            FQNLARRLHM-----KITLEEAEHFFLRIVRETVAFRE------------------------- 261

6a21m           FPNLARRLHM-----KMTAEPIERFFMRIVRETVAFRE------------------------- 261

6a21ps          FPKLSRKLHL-----KMTAEPIEQFFMRIVKETVKFRE------------------------- 263

6a17m           FPKLSRRLRL-----KLNIQEAEDFYTKIVRETIDYRL------------------------- 260

6a23m           FPKLSRRLRL-----KLNVQDVEDFYTSIVRNTIDYRL------------------------- 261

6A17ps          FPKLSRSLRL-----KLNVQEVEDFYTKIVRDTIDYRL------------------------- 259

6A23ps          FPKLSRSLRL-----KLNVQEVEDFYTKIVRDTIDYRL------------------------- 258

6a20ps          APKLAAKLRM-----KETVQKVEDFYMKIVRETVDYRL------------------------- 259

6a20m           APELAAKLRM-----KATVQEVEDFYMNIIRDTVDYRV------------------------- 271

6a19m           MPKLAVKLGF-----QFLLPSVQKFYMKIVQDTIDYRM------------------------- 261

6a22m           FPEVARFLRM-----RQIHQDITDFYVGIVRETVKQRE------------------------- 261

6A22ps          FPDLARRLRM-----CQIHQDITDFYLGIVKETVKLRE------------------------- 261

6a13m           QPELARKLRF-----RLFRPEVSEFFLDTVRQTLDYRR------------------------- 255

6A13ps          QPKLARMLHM-----RLFRPEVSEFFLETVRQTLAYRK------------------------- 255

6a14m           NARLARKLRI-----KVLPDDLTQFFMSTVKNTVDYRL------------------------- 272

6A14ps          NAKLAKKLRM-----KLLPDDVSEFFMNAVKNTVDYRM------------------------- 253

6a15pm          NSKLAKKLKM-----KILRDDLTDFFLSVVKPALSG--------------------------- 36

6a16m           YLSSLAKLGLPV---RILHPDITKFFNRIVRETVELRE------------------------- 257

6A16ps          YWSVLAKLKLSV---RFYDKIIADFFTRIVREKLELRQDL----------------------- 259

6u1m            FPLIARLLQY-----KSYAEPATAYFQKVALSQLQL-HRR----------------------- 252

6u1ps           FPLLAQLLNH-----KSYAVSAMTYFQKVVLGQLQE-QRR----------------------- 254

317a1m          FPNFCRMLRM-----RRTPKQAEEYFIKLLTSIVE--QRE----------------------- 270

317a1ps         FPNFCRVLRM-----RRTPKQAETYFLTLLSDIVG--QRE----------------------- 270

6g1m            LPKLVSLMRI-----QFFTADFSHFMRSTIGHVMEERE------------------------- 266

6G1ps           LPKLVSLLRI-----QFFTQEFAHFLRSTISHVMEERE------------------------- 268

6w1m            IPALASLARV-----KLFSRETTKFIRSSVNYVLKERE------------------------- 259

6w1ps           LPALTTLAKV-----KVFSKSTSQFIRSSINYVMAERE------------------------- 261

6v1m            LPKLVPLLRP-----KLFTEPHAEFLRRVIQLVIEERE------------------------- 272

6v1ps           LPKLVPLLRP-----RLFTEPHAEFLRRVIQLVIEERE------------------------- 273

6g2m            LPHLVPFVRF-----KVVPAEATRFLRKTINYVMSERE------------------------- 267

6g2ps           LPHLVPLFGF-----KVVPSEATRFLRNTINYVMAERE------------------------- 267

6t1m            FPRLSHRVGT-----HLYSEEYERFMRKSMDYVLSQRA------------------------- 283

6t2pm           -HHLFTRVRT-----HLYSEEYERFMRKSMNYVLAQRA------------------------- 247

6t1ps           FPRLSRMVRT-----HLYSDEYERFMRQSMDFVLAQRE------------------------- 287

6t3m            LPKWTGVLKP-----KVFTEDYARYMRH---LVDDHHE------------------------- 261

6t3ps           LPQWTNLLRA-----KVFSEEYAQFMRG---LVGHPRE------------------------- 262

9b1m            APKVFNFFKL-----TIFDSTNVEYFVRLVVDAMQYRE------------------------- 265

9b2m            VPKLFSLLKL-----TIFDSAKVDYFARLVVEAMQYRE------------------------- 265

9B2ps           IPKVFLFFNM-----KIFNGQKVEYFVRLVVDAMKYRE------------------------- 265

9f2m            LKGLNKILKV-----ELFDRKSTQYFVRLVLDAMKYRQ------------------------- 269

9f3pm           LKSLNKILKV-----EIFDRKSTQYFVRLVLDAMKYRQ------------------------- 269

9F2ps           LKSLNKYIKV-----DLFDKKSTEYFVRLVLDAMKYRQ------------------------- 270

9c1m            MPKLMKALRV-----PVMDMNNVDYFKKLVFGAMKYRK------------------------- 265

9c1ps           LPKLMKALRV-----SVMDMNNVDYFKKLVFGAIQHRK------------------------- 268

9h1m            FPRLMKVLRI-----QVLDTKNIDYFSSLVTAAMRYRQ------------------------- 267

9h1ps           VPRLMKLLRI-----QVLDFEKIDYFTSLVKVAMRYRK------------------------- 267

6d2m            CPPIAKLMNR-----LGYESRILTSLRDMMKRTIEFRE------------------------- 257

6d2ps           CPPIAKLMNR-----LGFESAILTALRDMMKRTIEFRE------------------------- 261

6d4m            VPSIAQFLFR-----IGFKNPVGLAMLQIVKETVEYRE------------------------- 260

6d4ps           VPSVAKFLFS-----LGFKNQVALAMLEIVKETIEYRE------------------------- 260

6d5m            YPGLEKFFVK-----IGWKQEATERMRELSNRTVDLRE------------------------- 258

6D5ps           FPGLEKIFVR-----LGWSQEGPERIRELSNRTVDLRE------------------------- 258

310a1m          QSFT---LGR-----LPQKSSYTYRLRDLIKQSVELRE------------------------- 229

310a1ps         QSFT---LSR-----LPQKSSFTYRLRDLIKQGVEHRE------------------------- 230

28a5m           FPSLSHLIKL-----RFVPVDVERFFVDLMGSAVETRRAQLAA-------------------- 270

28A5ps          FPSLSHLIKL-----RFVPPKVERFFIELMENAVKARRAQLVA-------------------- 270

28d1m           WPPITKFYSV-----SLFAKDVAAFFYDLMQKCIQVRRESPAA-------------------- 272

28d1ps          WPPIRKIYSV-----PLFAKEVEQFFFDIMEKCIILRRENPKQ-------------------- 272

28d2m           WQKVRKFYSV-----PFFNKETEVFFLDIIRRCITLRLEKPEQ-------------------- 272

28c1m           FPNLPRWLRP-----KVFPRSHDRFYGQMISEALRLRRSKHQ--------------------- 267

28c1ps          FPRLPRWLRP-----KIFPRSYDRFFGDLIRQAFSLRRGQHQ--------------------- 267

309a1m          AIFVRKLFSM-----RFFTKATDEFFLRLTQDAVNLRQGGS---------------------- 275

309a1ps         APFLRKVLQM-----RFFTKTAEQFYLQLTRDALRLRHSGS---------------------- 275

309a2m          APCSRLLLRF-----RFYPKETDEFFSNLTKESIELRLKAG---------------------- 274

309a2ps         APFSRLLLRL-----RFYPKETDEFFSRLTKESIDMRLSAGN--------------------- 277

308a1m          TPRLGRLIGH-----RYVPLPLQHWFRELVEARSGG--------------------------- 258

308a1ps         SSRLANILQH-----RYVPLSLQDWLCALVRARSGA--------------------------- 267

4aa1m           WTKMAN--DE-----LNQKKRLNDFTRKMIQRRRQIQNNN----------------------- 278

4aa1ps          WTKLAN--DE-----LNQKKRLHDFTRQMIKIRREILANTG---------------------- 290

4C3m            LTAEYKLHQ-------SYINTLHGFSNMVIRERKAELAILQENNNNNNNN------------- 297

4C3ps           LTADYKLHQ-------SYINTLHGFSNMVIRERKSELALLQDNNNNNNN-------------- 296

4d1m            LTPLARAEK-------KALNVLHQFTEKIIVQRREELIREGS---SQES-------------- 272

4D1ps           LTPLARAEK-------RALHVLHEFTEKIIVQRREELIRGGSKDAAAAS-------------- 275

4d1malt         LTPLARAEK-------KALNVLHQFTEKIIVQRREELIREGS---SQES-------------- 263

4D1psalt        LTPLARAEK-------RALHVLHEFTEKIIVQRREELIRGGSKDAAAAS-------------- 276

4s3m            HTKPGKERE-------AALKVLHDETNRVIRLRREQLIQER-----NEWK------------- 261

4s3ps           YTQAGQERD-------GALRVLHDETNRVIRLRREQLVKERQ----LQQR------------- 262

312a1m          RTSHYKREQ-------ELIKTLHGFTEGIIQKRIDEINQDAE----NRNY------------- 270

312a1ps         RTALFRREQ-------ELLKTLHGFTEGIVQERQHQFNLDEV----NRNT------------- 271

4g1m            FTKLREKGD-------RMMNIILGMTSKVVKDRKENFQEESRAIVEEISTPVASTPASKKEGL 306

4G1ps           FTKLREKGD-------RMMNIILGMTSKVVKDRKQNFQEESRAIVDEVQA--VSTPATKKEGL 302

4g15m           LTRYYKEQG-------RLLNIIHGLTTKVIRSKKAAFEQGTRGSLAQCELKAAALEREREQNG 294

4G15ps          LTRYYKEQG-------RLLSIIHGLTTKVIRSKKAAFEQGTRGSLAQCELKAAALERERGQEQ 294

4d2m            LTQPTEAKRQ-----DKAIKVMHDFTENIIRERRETLVNNSKETT-PEEE------------- 270

4D2ps           LVHPGMAKRQ-----DSAIKVMHDFTENIIKQRRQALVSAGKQEK-EKEE------------- 271

4d14m           LFYPKLLDKL-----NDAVKNMHDFTNSVITERRELLQKAIADG--GDAD------------- 271

4d14ps          LFFPSAFAKL-----SANIKAMQDFTNNVISERRDLLQKSISDGTYETTN------------- 273

4d8m            LTHPHLKWRQ-----TQLIRTMQEFTIKVIEKRRQALEDQQ-----SKLM------------- 265

4d8ps           LTHPYMKWRQ-----TQLIRTMHDFTTKVIEERRRTLEEQQG----SKLS------------- 266

4ae1m           LCWPSGFRKQ-----QAGVICLHEFTNGIIEQRRRLLAREA---------------------- 264

4AE1ps          LCWPSGFRKQ-----QEGIKCLHLFTNSIIEQRRQLLRREN---------------------- 266

4d20m           LAAPLLHRQL-----LSDIRVMHDFTDKVISERRETVRRAKADG-TYRPL------------- 272

4D20ps          LTCPVLRSKL-----LKDVRVMHDFTDKVIRERRAAVEQAKADG-SYRPL------------- 273

4d21m           LAAPLVYRRL-----QKDIAIMQDFTDKVIRERRAILERARADG-TYKPL------------- 272

4e2m            LAPDYPAYS-------RTLKTLQDFTNEIIAKRIEAHKSGA-------VS------------- 264

4e2ps           LAPDYPAYC-------KTLKTLQDFTNNIIEKRIKAHKDGT-------VS------------- 264

4e1m            FAPEYPEYS-------KTLKTLQDFTNEIIAKRIEVRKSGL-------EV------------- 264

4e1ps           FASDYPAYC-------KTLKTLQDFTHDVIEKRLNAHKEGT-------VL------------- 264

4e3m            LTPEFSAYQ-------KTLKTLQDFTYDIIEKRVYALQNGG-------SK------------- 264

4e3ps           LSPEYAAYQ-------RTLKTLQDFTYDIIEKRVETLQAGQ-------NS------------- 264

4ad1m           LTSYYMKQR-------RALSLLRSELNRIISQRRHQLAAEN-------TC------------- 266

4AD1ps          LTSYYMKQR-------RALSLLRREIYRIITQRRQQLADEN-------TC------------- 266

4p1m            MFAAK---DF-----ASALDVVHRFSSEIIAKRRDLLKDELDK--SSSTA------------- 279

4p3m            MFAEK---DY-----ASALDVVHGFSSEIIAKRRDQLNDEIDSRGNTQTA------------- 281

4p1ps           WFAAK---TY-----DAFLKTVHEFSSEIIAKRRILLEEELEHRRSTQTA------------- 281

4P2ps           WFAAK---TY-----DAFLKTVHEFSSEIIAKRRILLEEELEHRRLTQTA------------- 283

4P3ps           LFVAK---EY-----APFLKVVHDFSSEIIAKRRILLEEELEHRRSTQTA------------- 282

4p2m            MFTGH---KY-----NAALKVVHEFSREIIAKRRVLLEEELENRRATQTA------------- 283

4ac1m           VYGDYR--KH-----LQNLRIVHDFSSRIIERKRQQFQQKQLG-------------------- 276

4AC1ps          LIGDYR--KQ-----VQNLRIVHDFSSRIIERKRQQFKRKQLG-------------------- 276

4ac2ps          LYGDYR--KH-----IDSLKIAHDFSSSIIERRRRDIKRKELG-------------------- 277

4ac2m           LFGDYR--KQ-----VNNLKIAHEFSSNIIEKRRSLFKSNQLG-------------------- 277

4ac3m           LFGDYK--KY-----SRILRTIHGFSSGIIQRKRQQFKQKQLG-------------------- 276

311a1m          RTQLWR--DL-----DEQLQVIHSQMESVIEKRAKELLDMGE--------------------- 256

311a1ps         QTRLWR--EL-----SEQLQVIHTLMDSLIDRRSAQLQQQGN--------------------- 205

316a1m          LSSPFMRKRQ-----NRLIKRLNDEHNNLMAMHQ---SQNQLKIEN--G-------------- 256

316A1ps         VSSPLLRRRQ-----AQLIKQLNDEHKEHIDRFRRLQKQEEQLKAG--N-------------- 260

313a2m          LFGLEWLR-------RRDASAINKMINNILDKKLNSNPENYCE-------------------- 263

313a3m          LGGFETQK-------ALAKSNVNKMIGTIVDKKLMTKPESGSQ-------------------- 263

313a1m          ICGYDKLR-------ADNFSRIQKMLDNVVNKKVNPLPKTDSD-------------------- 263

313C1ps         LFGFEKRK-------SEAMIHLNASLQSILQEKLKTQGDESKE-------------------- 262

313C2ps         LLGIEKRR-------TEATFIVNELTKSLIEEKMTNKPDENQE-------------------- 262

313a5m          LFSYEKRR-------LEAATQSNAFIKDIIDKKLSSTDNSSEP-------------------- 262

313a4m          LAGKESHY-------YQAKTEIRQFIRKIIERKLAEDEMGALP-------------------- 261

313a4ps         LSGKEANY-------YRAKTEIRAFIRKLIQKRLSEDTEDSIK-------------------- 261

313A4bps        LTGREKNY-------HRSKTEIRAFLNKLIQKRLAEDTEDSIK-------------------- 259

313b1m          RSGLFRLQ-------QKVVGILFGFIEQLLEPIVSVVAANSNPDQQRSEM------------- 269

313b1ps         RSRLFVQQ-------TKVVGVLRGFIEQLLSPIVSVVDLDTS--KEPLQQ------------- 268

318a1m          LLAPELYEES-----KKCAKLLEDFVGGIVRTKHRNWRLRDAVGGEKS-G------------- 275

318A1ps         LLAPELYAEA-----EKCNQLLVEFVAGIVQSKHRNWQLRAALCEG---A------------- 273

18a1m           CFPSISTAKNK---IAQNRAEMQRFYQDVIDDHKRSFDP------------------------ 282

18a1ps          CFPSISTAKNK---IAQNRAEMQRFYQDVIDDHKRSFDP------------------------ 283

306A1m          HLPANVRNIRF---LLEGKAKTHAIYDRIVEACGQRLKEKQKVF------------------- 289

306A1ps         RLPWNRRNICF---LMEGKSRTHAIYDRIVESCENRLKELQEQY------------------- 294

303a1m          FIAPNFSGYNG---FVESHRSLYTFMSKEIELHRLTYKNYDE--------------------- 273

303A1ps         FIAPDYSGYNG---FVESHRALYSFMSKEIELHRRTYRSFDE--------------------- 273

305a1m          HVAPDRTGYNL---IQQLNTELYGFFMDTIEEHRRQLAKDPS--------------------- 268

305A1ps         HVAPDRTGYNL---IRQLNTELYGFFMDTIADHRRQLEKASDN-------------------- 269

304a1m          HIWPEWSGYNK---LNESNLFVRQFFADFVDKYLDSYEEGVE--------------------- 281

304a1ps         HVWPEWSGYKK---LNESNQFMRQYFAEIVDRHIETYEEGSE--------------------- 281

307a1m          PFYQR--HLNK---IINWSSTIRGFIMERIIRHRELSVDLDE--------------------- 293

307a1ps         PFYRR--HLNK---IVHWSSTIRSFIMDRIISHRELDIDVDE--------------------- 288

307a2pm         ---------------------------------------------------------------

307a2pps        PFYKN--HTQK---IVQWSTTIRKFILDRVIHQREEMLDLDE--------------------- 288

 

                                                         8A  8B

12a4m           -------------------------------------------------EGVVR--PENE 308

12a5m           -------------------------------------------------EGVVR--PEHE 308

12A4ps          -------------------------------------------------EGVVR--PESE 307

12A5ps          -------------------------------------------------EGVVR--PENE 307

12c1m           -------------------------------------------------Q--GD--SNDH 298

12c1ps          -------------------------------------------------A--AE--REGR 307

12e1m           -------------------------------------------------AGTLN-EIGLE 291

12e1ps          -------------------------------------------------AGKMSPEMGME 294

12d1m           -------------------------------------------------AG--EK--INS 300

12d1ps          -------------------------------------------------AG--EQ--VNS 300

12b2m           -------------------------------------------------DG--K-----T 306

12B2ps          -------------------------------------------------GR--K-----N 309

49A1m           -------------------------------------------------RGLSKSEADIS 364

49A1ps          -------------------------------------------------RALPKSEADIS 369

301a1m          ----------------------------------------------------SLRAGEPS 335

301A1ps         ----------------------------------------------------SQRAGEPS 340

302a1m          --------------------------------------------------VRNGSVGSSL 271

302A1ps         ----------------------------------------------------SSSEQSSL 269

314a1m          -------------------------------------------------EDDEAAGLRSI 323

314a1ps         -------------------------------------------------DDEGASGLRSV 324

315a1m          -------------------------------------------------QEDQRRPHDEA 316

315a1ps         -------------------------------------------------HLEQLEQREET 318

6a2m            -----------------------------------------------RENFKRNDFMNLL 275

6a2ps           -----------------------------------------------KENFKRHDFMDML 275

6a8m            -----------------------------------------------KEHIKRNDFMDML 275

6a18m           -----------------------------------------------KENIKRNDFMDML 275

6a8ps           -----------------------------------------------KENIKRNDFMDLL 275

6a9m            -----------------------------------------------KNNIRRNDFMDQL 274

6a21m           -----------------------------------------------QNNIRRNDFMDQL 274

6a21ps          -----------------------------------------------QNQIRRNDFMDQL 276

6a17m           -----------------------------------------------RTKEKRNDFMDSL 273

6a23m           -----------------------------------------------RTNEKRHDFMDSL 274

6A17ps          -----------------------------------------------KTKEKRNDFMDSL 272

6A23ps          -----------------------------------------------KTKEKRNDFMDSL 271

6a20ps          -----------------------------------------------KNNVKRNDFMDML 272

6a20m           -----------------------------------------------KNNVKRHDFVDML 284

6a19m           -----------------------------------------------KRKVTRNDFMDTL 274

6a22m           -----------------------------------------------EQGIVRSDFMNLL 274

6A22ps          -----------------------------------------------EQGIVRNDFMNLL 274

6a13m           -----------------------------------------------RENIHRN---DLI 265

6A13ps          -----------------------------------------------RENVQRS---DLI 265

6a14m           -----------------------------------------------KNGIKRNDFIEQM 285

6A14ps          -----------------------------------------------KNGIKRNDFLDEL 266

6a15pm          --------------------------------------------------------MTLW 40

6a16m           -----------------------------------------------RENIRRNDFMDLL 270

6A16ps          -----------------------------------------------RHNIKRNDFLELL 272

6u1m            -----------------------------------------------RDRQPLQTFLQLY 265

6u1ps           -----------------------------------------------RDRQPLQTFLQLY 267

317a1m          -----------------------------------------------TSGKPQKDYLQLL 283

317a1ps         -----------------------------------------------ASGVRHQDYLQLL 283

6g1m            -----------------------------------------------RSGLLRNDLIDVL 279

6G1ps           -----------------------------------------------RTGFVRNDLIDVL 281

6w1m            -----------------------------------------------RTGEKRNDLIDIL 272

6w1ps           -----------------------------------------------RSGLRRNDLVDVL 274

6v1m            -----------------------------------------------RGGDLRNDLIEML 285

6v1ps           -----------------------------------------------RGGDLRNDLIEML 286

6g2m            -----------------------------------------------KSGQKRNDLIDIL 280

6g2ps           -----------------------------------------------RSQQTRNDLIDIL 280

6t1m            -----------------------------------------------ESGENRHDLIDIF 296

6t2pm           -----------------------------------------------EN-EKRYDLIDMF 259

6t1ps           -----------------------------------------------KSGEKRHDLIDIF 300

6t3m            -----------------------------------------------PT--K-GDLINQL 271

6t3ps           -----------------------------------------------RS--K-GDLIDQL 272

9b1m            -----------------------------------------------KHNITRPDMIQLL 278

9b2m            -----------------------------------------------KHNITRPDMIQLL 278

9B2ps           -----------------------------------------------EHNINRPDMIQLL 278

9f2m            -----------------------------------------------EHNIVRPDMINML 282

9f3pm           -----------------------------------------------EHNIVRPDMINML 282

9F2ps           -----------------------------------------------EHNIIRPDMINML 283

9c1m            -----------------------------------------------EQSIVRPDMIHLL 278

9c1ps           -----------------------------------------------EHNIIRPDMIQQL 281

9h1m            -----------------------------------------------EHKVVRPDMIHLL 280

9h1ps           -----------------------------------------------EHNVLRPDMIHLL 280

6d2m            -----------------------------------------------EHNVVRKDMLQLL 270

6d2ps           -----------------------------------------------SNNVVRKDLLQLL 274

6d4m            -----------------------------------------------KHGIVRKDLLQLL 273

6d4ps           -----------------------------------------------KHGIVRKDLLQLL 273

6d5m            -----------------------------------------------QNNIVRKDLLQLL 271

6D5ps           -----------------------------------------------EKNIERRDLLQLL 271

310a1m          -----------------------------------------------DHGLIRKDILQLL 242

310a1ps         -----------------------------------------------EHGLIRKDILQLL 243

28a5m           -----------------------------------------------GKQFERSDFLDYI 283

28A5ps          -----------------------------------------------GKQFERTDFLDYI 283

28d1m           -----------------------------------------------QQ---RDDFLNYM 282

28d1ps          -----------------------------------------------Q----REDFLNYM 281

28d2m           -----------------------------------------------Q----RDDFLNYM 281

28c1m           -----------------------------------------------E----RNDFINHL 276

28c1ps          -----------------------------------------------E----RNDFINHL 276

309a1m          -------------------------------------------------GEGRTDYLSHL 286

309a1ps         -------------------------------------------------GSDRTDYLSHL 286

309a2m          -------------------------------------------------DSTRTDYLSHL 285

309a2ps         -------------------------------------------------DITRTDYLSHL 288

308a1m          -----------------------------------------------------DNLLQWL 265

308a1ps         -----------------------------------------------------NNFLHWL 274

4aa1m           -----------------------------------------------NGNSERKCLLDHM 291

4aa1ps          -----------------------------------------------NNNAERKCLLDYM 303

4C3m            ----------------------------------------APDAYDDVGKKKRLAFLDLL 317

4C3ps           ----------------------------------------TPDAYDDVGKKKRLAFLDLL 316

4d1m            -----------------------------------------SNDDADVGAKRKMAFLDIL 291

4D1ps           -----------------------------------------DDADADVGAKRKMAFLDIL 294

4d1malt         -----------------------------------------SNDDADVGAKRKMAFLDIL 282

4D1psalt        -----------------------------------------DDADADVGAKRKMAFLDIL 295

4s3m            ----------------------------------------PEAEQDDVGAKRRLAFLDML 281

4s3ps           ----------------------------------------TEAAQDDVGSKRRLAFLDML 282

312a1m          ----------------------------------------QSSDAELDGVKRTLCFLDTL 290

312a1ps         ----------------------------------------MSTKDAEMDKRPALSFLDTL 291

4g1m            R------------------------------------DDLDDIDENDVGAKRRLALLDAM 330

4G1ps           R------------------------------------DDLDDIDENDVGAKRRLALLDAM 326

4g15m           GVDQTPSTAGSDEKDREKDKEKASPVAGLSYGQSAGLKDDLDVEDNDIGEKKRLAFLDLM 354

4G15ps          KQEQKQEQAEMGSAGGGKAAGEGTPVAGLSYGQSAGLKDDLDVEDNDIGEKKRLAFLDLM 354

4d2m            -----------------------------------------VN---FLGQKRRMALLDVL 286

4D2ps           -----------------------------------------IKEDDDLGQKRRMALLDVL 290

4d14m           -----------------------------------------AALLNDVGQKRRMALLDVL 290

4d14ps          -----------------------------------------ASPLDDVGQKRRMALLDVL 292

4d8m            -----------------------------------------DTADEDVGSKRRMALLDVL 284

4d8ps           -----------------------------------------PSPDDDVGRKRRMALLDVL 285

4ae1m           ------------------------------------------NQDKPTKP---HALLDTL 279

4AE1ps          ------------------------------------------APGEPVARDRRNALLDTL 284

4d20m           -----------------------------------------SLGDAEIGSKSQMALLDIL 291

4D20ps          -----------------------------------------SLGDPEVGRKSQMALLDIL 292

4d21m           -----------------------------------------IMGDDDIGGKAKMTLLDIL 291

4e2m            -----------------------------------------TNAGDEFTRKK-MAFLDTL 282

4e2ps           -----------------------------------------ASQGDEFSRKK-MAFLDTL 282

4e1m            -----------------------------------------GIKADEFSRKK-MAFLDTL 282

4e1ps           -----------------------------------------ASHGDEFSRKK-MVFLDTL 282

4e3m            -----------------------------------------EDHDPSLPRKK-MAFLDTL 282

4e3ps           -----------------------------------------SSADSSSPRKK-MAFLDTL 282

4ad1m           -----------------------------------------QQ-GQPINKP----FLDVL 280

4AD1ps          -----------------------------------------GERTKKINKP----FLDVL 281

4p1m            ------------------------------------------DDDGFVS-KKRFAMLDTL 296

4p3m            ------------------------------------------EDELFTS-KKRFAMLDTL 298

4p1ps           ------------------------------------------DDDIFGSRKKRFAMLDTL 299

4P2ps           ------------------------------------------DDDIFVSRKKRFAMLDTL 301

4P3ps           ------------------------------------------DDDIFVSRHKRFAMLDTL 300

4p2m            ------------------------------------------DDDICVIRKKRFAMLDTL 301

4ac1m           -------------------------------------------EVDEFGRKQRYAMLDTL 293

4AC1ps          -------------------------------------------VVDDFGKKQRYAMLDTL 293

4ac2ps          -------------------------------------------VVDDFGKKQRYAMLDTL 294

4ac2m           -------------------------------------------QEDEFGKKQRYAMLDTL 294

4ac3m           -------------------------------------------QVDEFGKKQRYAMLDTL 293

311a1m          ------------------------------------------------PAGRAHNLLDTL 268

311a1ps         ------------------------------------------------EPRKALNLLDTL 217

316a1m          ---------------------------------------LDIYQLRPIPLKDHKSLLEIL 277

316A1ps         ---------------------------------------VVVDRIDPLPAQWHQSLLEIL 281

313a2m          ----------------------------------------------S--EL--KTVIHRA 273

313a3m          ----------------------------------------------P--EI--TSVINKA 273

313a1m          ----------------------------------------------P--ES--NIVINRA 273

313C1ps         ----------------------------------------------S--LASRNIVINRA 274

313C2ps         ----------------------------------------------S--FAIRNTVISRV 274

313a5m          ------------------------------------------------------ALIDRI 268

313a4m          ----------------------------------------------SIQSNDKNLFLNLV 275

313a4ps         -------------------------------------------------SKDKNIFLNLA 272

313A4bps        -------------------------------------------------SKDKNIFLHVT 270

313b1m          --------------------------------------------EM--RGKSKAIFIEQV 283

313b1ps         --------------------------------------------ES--KSKSKSIFIEQV 282

318a1m          --------------------------------------------EDASNGWQRRIFIEQI 291

318A1ps         --------------------------------------------GEDSTAWQRRIFIEQI 289

18a1m           --------------------------------------------------NNIRDLVDFY 292

18a1ps          --------------------------------------------------HNVRDLVDYY 293

306A1m          ----------K---------------------------------ELQEQKRLQRQLEKEQ 306

306A1ps         ----------Q---------------------------------EKQRQRQQQQDLQQYQ 311

303a1m          ----------------------------------------------------PRDLMDSY 281

303A1ps         ----------------------------------------------------PRDLMDSY 281

305a1m          --------------------------------------------------PAESDLIYAY 278

305A1ps         -------------------------------------------------EPVESDLIYAY 280

304a1m          -----------------------------------------------------RNFMDVY 288

304a1ps         -----------------------------------------------------RNFIDLY 288

307a1m          ---------------------------------------------------PDRDFTDAL 302

307a1ps         ---------------------------------------------------PDSDFTDAL 297

307a2pm         ------------------------------------------------------------

307a2pps        ---------------------------------------------------PENDFTDAL 297

 

                                            9A 9B     9C

12a4m           QSVLEKL---------------------------LKVDR--------------------- 320

12a5m           QSVLEKL---------------------------LKVDK--------------------- 320

12A4ps          QSVLEKL---------------------------LKVDK--------------------- 319

12A5ps          QSVLEKL---------------------------LKIDK--------------------- 319

12c1m           KSVLEQL---------------------------LQIDR--------------------- 310

12c1ps          RSILEQL---------------------------LQINR--------------------- 319

12e1m           TSLLEKL---------------------------ARFDR--------------------- 303

12e1ps          ASLLEKL---------------------------ARFDR--------------------- 306

12d1m           NSMLERL---------------------------MEIDP--------------------- 312

12d1ps          HSMLQRL---------------------------MDIDP--------------------- 312

12b2m           KCVLEQL---------------------------LEHNK--------------------- 318

12B2ps          KCVLEQL---------------------------LGLNK--------------------- 321

49A1m           IVERIVR---------------------------KTGNR--------------------- 376

49A1ps          IVERIVR---------------------------KTGNR--------------------- 381

301a1m          LVEKVIL---------------------------SQKDE--------------------- 347

301A1ps         LVEKVIM---------------------------SEKDE--------------------- 352

302a1m          ISAYVKN---------------------------PELDR--------------------- 283

302A1ps         ISTYLQN---------------------------PELDH--------------------- 281

314a1m          FLNILEL---------------------------KDLDI--------------------- 335

314a1ps         FLNILDL---------------------------KDLDI--------------------- 336

315a1m          LYHRLQA---------------------------ADVPG--------------------- 328

315a1ps         LFNRLQA---------------------------AEVPG--------------------- 330

6a2m            IELKQKGRV--------------TLDNG---EVIEGMDI--------------------- 297

6a2ps           IEIKQKGSV--------------TLENG---EVMKAMDI--------------------- 297

6a8m            IELKNQKEM--------------TLENG---DVVRGLTM--------------------- 297

6a18m           IGLKNQKNM--------------TLENG---EVVKGLTM--------------------- 297

6a8ps           IDMKNQK-V--------------KLENG---DLVDGLTI--------------------- 296

6a9m            IDLKNSPLT--------------KSESG---ESVN-LTI--------------------- 295

6a21m           IDLKNKPLM--------------VSQSG---ESVN-LTI--------------------- 295

6a21ps          IDLKNNQII--------------KTESG---DNIN-LTI--------------------- 297

6a17m           IEMYKNE----------------QS--G---NSEDGLTF--------------------- 291

6a23m           IEMYEKE----------------QA--G---NTEDGLSF--------------------- 292

6A17ps          IEMYQKE----------------QE--G---NSDEGLTF--------------------- 290

6A23ps          IEMYQKE----------------QE--G---NSDEGLTF--------------------- 289

6a20ps          IDMKINY----------------DK--G---NKQDGISF--------------------- 290

6a20m           IEMKLKF----------------DN--G---DKENGLTF--------------------- 302

6a19m           IDMKQQY----------------DK--G---DKENGLAF--------------------- 292

6a22m           IEMKQRG----------------E------------LTI--------------------- 285

6A22ps          IEMKHRG----------------E------------LTL--------------------- 285

6a13m           QLLMELGEE--------------G--------VKDALSF--------------------- 282

6A13ps          QLLMDLGEE--------------G--------TKDGLSF--------------------- 282

6a14m           IELRAEDQE--------------AAKKGQGIDLSHGLTL--------------------- 310

6A14ps          IELRAENQE--------------AAKHGKVIDLSHGLTI--------------------- 291

6a15pm          TSPPSGGRS--------------SRQGGSKFDLSHNWTL--------------------- 65

6a16m           LDLRR-----------------------------KGLTM--------------------- 307

6A16ps          MAS--------------------K--------DDNELTL--------------------- 283

6u1m            SNAEKP------------------------------LTD--------------------- 274

6u1ps           SNMDQP------------------------------LDD--------------------- 276

317a1m          IDVKALEFIT------------HQYEAD---KELGAHLQ--------------------- 307

317a1ps         VEIKALELIT------------HQYQAD---KELNTHLQ--------------------- 307

6g1m            VSLRKEAAAEPSK-------------------PHYAKNQ--------------------- 299

6G1ps           VGLRKEAAEEPSK-------------------PHYARNF--------------------- 301

6w1m            LALKREAAANPGK-------------------MSKEVDL--------------------- 292

6w1ps           LALKREAAASPDK-------------------NNKAKNM--------------------- 294

6v1m            LTLKKEADLQQDK-------------------SHFTHHR--------------------- 305

6v1ps           LTLKKEADLQKDK-------------------SHFTHHR--------------------- 306

6g2m            IEFRRSTQLAKASG----------------IKDQFVFEG--------------------- 303

6g2ps           IEFRRSTQQARAAG----------------DHGQFVFEG--------------------- 303

6t1m            LQLKRTEPAE-----------------------SIIHRP--------------------- 312

6t2pm           LQMHRTETAE-----------------------GIIHRP--------------------- 275

6t1ps           LQLKRTEPPT-----------------------SIIHRP--------------------- 316

6t3m            QHFQLSRSSN-----------------------HYSQHP--------------------- 287

6t3ps           LHLQSSRPSS-----------------------HYAQHP--------------------- 288

9b1m            MEAK--------------------------KESKDNWTD--------------------- 291

9b2m            MEAK--------------------------NESEDKWTD--------------------- 291

9B2ps           MESK--------------------------TESEDNWTD--------------------- 291

9f2m            MEARGIIQTE-----------------KTKASAVREWSD--------------------- 304

9f3pm           MEARGIIQTE-----------------KTKASAVREWSD--------------------- 304

9F2ps           MEARGLFQTE-----------------KTKTTVIREWSD--------------------- 305

9c1m            MEAQRQFKAEQEGSAE-----------SAAQQDKAEFND--------------------- 306

9c1ps           MEAQRLFRAEQEASQE-----------TTTQEDRAEFND--------------------- 309

9h1m            MEAKQQRLADLSDKSK-----------DELY--YSEFTA--------------------- 306

9h1ps           MEAKQLRHAELVNQSK-----------DSSR--YADFTD--------------------- 306

6d2m            IRLRNTGKIGEDDDQV-------WDM-ETAQEQLKSMSI--------------------- 301

6d2ps           IRLRNTGRIGEDDDEV-------WDM-ETVQEELKAMSI--------------------- 305

6d4m            IQLRNTGKIDENDEKS-------FSIQKTPDGHIKTISL--------------------- 305

6d4ps           MELRNTGAVDESDENI-------WKIQKSATDQIKCISL--------------------- 305

6d5m            LQLRNQGKIN-TDDNI-------WSA-ESTKNGVKSMSK--------------------- 301

6D5ps           LQLRNTGKIS-NDDNM-------WSA-QNDNKGLKSVSK--------------------- 301

310a1m          VRFRNGN--EVSGDK--------WQL-EPINDADKLLSI--------------------- 270

310a1ps         TRFRNGN--DISGDK--------WQI-DIDNEQDKLLSI--------------------- 271

28a5m           LQLGE----------------------------KRNLDN--------------------- 294

28A5ps          LQMAE----------------------------KRSLDT--------------------- 294

28d1m           LQLQE----------------------------KKGLNA--------------------- 293

28d1ps          LQLQE----------------------------KKGLDT--------------------- 292

28d2m           LQLQE----------------------------KKGLHT--------------------- 292

28c1m           LEMQR----------------------------ELDLSE--------------------- 287

28c1ps          LALKR----------------------------EHGLTE--------------------- 287

309a1m          IQLQ-----------------------------QRGNSI--------------------- 296

309a1ps         IQLQ-----------------------------QRGITL--------------------- 296

309a2m          LQLRD----------------------------QKQATH--------------------- 296

309a2ps         LQLRE----------------------------QKQASH--------------------- 299

308a1m          AESK------------------------------RGLGK--------------------- 274

308a1ps         GDKQ------------------------------GEQG---------------------- 282

4aa1m           IEISES---------------------------NRDFTE--------------------- 303

4aa1ps          IEISES---------------------------NPDFTE--------------------- 315

4C3m            IDASKEG---------------------------TVLSN--------------------- 329

4C3ps           IDASKDG---------------------------TVLTN--------------------- 328

4d1m            LQSTVDE---------------------------RPLSN--------------------- 303

4D1ps           LQSTIDE---------------------------KPLTN--------------------- 306

4d1malt         LQSTVDE---------------------------RPLSN--------------------- 294

4D1psalt        LQSTIDE---------------------------KPLTN--------------------- 307

4s3m            LLTQMEG--------------------------GAELSD--------------------- 294

4s3ps           LLTQLEG--------------------------GDELSD--------------------- 295

312a1m          LLSKGPD--------------------------GKPLTV--------------------- 303

312a1ps         LQAKTPE--------------------------GASLSV--------------------- 304

4g1m            VEMAKNP--------------------------DIEWNE--------------------- 343

4G1ps           VEMAKNP--------------------------DIEWNE--------------------- 339

4g15m           LESAQN---------------------------GALITD--------------------- 366

4G15ps          LESAQN---------------------------GALITD--------------------- 366

4d2m            LQSTID---------------------------GAPLSD--------------------- 298

4D2ps           LQSTID---------------------------GASLSN--------------------- 302

4d14m           LKSTID---------------------------GAPLSN--------------------- 302

4d14ps          LQSSID---------------------------GAPLSN--------------------- 304

4d8m            LMSTVD---------------------------GRPLTN--------------------- 296

4d8ps           LLATVD---------------------------GRPLTN--------------------- 297

4ae1m           LRATVD---------------------------GQPLTD--------------------- 291

4AE1ps          LRATVD---------------------------GQPLTD--------------------- 296

4d20m           LQSSIN---------------------------NQPLSD--------------------- 303

4D20ps          LQATIE---------------------------GQPLSD--------------------- 304

4d21m           LQATID---------------------------NKPLSD--------------------- 303

4e2m            LSSTID---------------------------GRPLNS--------------------- 294

4e2ps           LSSTID---------------------------GRPLTT--------------------- 294

4e1m            LSSKVD---------------------------GRPLTS--------------------- 294

4e1ps           LSATVD---------------------------GRPLTS--------------------- 294

4e3m            LSSTID---------------------------GRPLTR--------------------- 294

4e3ps           LSSTVD---------------------------GRPLTR--------------------- 294

4ad1m           LTAKLD---------------------------GKVLKE--------------------- 292

4AD1ps          LAAKLD---------------------------GRALKE--------------------- 293

4p1m            IYAEKD----------------------------GLIDH--------------------- 307

4p3m            ILAEKD----------------------------GLIDH--------------------- 309

4p1ps           ICAEKD----------------------------GLIDH--------------------- 310

4P2ps           ICAEKD----------------------------GLIDH--------------------- 312

4P3ps           ICAEKD----------------------------GMIDH--------------------- 311

4p2m            ICAEKD----------------------------GLIDD--------------------- 312

4ac1m           LAAEAD----------------------------GQIDH--------------------- 304

4AC1ps          LAAEAE----------------------------GQIDH--------------------- 304

4ac2ps          LAAEAD----------------------------GQIDH--------------------- 305

4ac2m           LAAEAD----------------------------GQIDH--------------------- 305

4ac3m           LAAEAE----------------------------GKIDH--------------------- 304

311a1m          LLAKFE---------------------------GQSLSR--------------------- 280

311a1ps         LLANID---------------------------GEPLSR--------------------- 229

316a1m          LE-SKD----------------------------PQLTG--------------------- 287

316A1ps         LAGNHN----------------------------PEISD--------------------- 292

313a2m          IELFRN----------------------------DEMSL--------------------- 284

313a3m          IELHRN----------------------------GEMSR--------------------- 284

313a1m          MELYRK----------------------------GDITY--------------------- 284

313C1ps         RDFLRS----------------------------GDFSY--------------------- 285

313C2ps         VEFLKS----------------------------GEFSY--------------------- 285

313a5m          LNLVRI----------------------------GELSY--------------------- 279

313a4m          TDLMRR----------------------------GVFTL--------------------- 286

313a4ps         TDLLRR----------------------------GVFDW--------------------- 283

313A4bps        TDLLKR----------------------------GVFDL--------------------- 281

313b1m          REHVER----------------------------GQLSW--------------------- 294

313b1ps         REHVER----------------------------GQLSW--------------------- 293

318a1m          FQLAAN----------------------------GEMTL--------------------- 302

318A1ps         FQLAAN----------------------------GELTL--------------------- 300

18a1m           LC--------------------EIEKAKAEGTDAELFDG--------------------- 311

18a1ps          LC--------------------EIEKAKAEGTDAELFDG--------------------- 312

306A1m          LR-------------QSKEADPSQEQSEADEDDEESDEEDTYEPECILEHFLAVRDTDSQ 353

306A1ps         QQDPQQDPEPESGSEQSLQQSPEQKEEKPKGEEEEDDDDDVYEPTCILEHFLINRVPFSE 371

303a1m          LRAQ-----------------------DEGNDEKGMFSD--------------------- 297

303A1ps         LRAQ-----------------------EAGNDDKGMFSD--------------------- 297

305a1m          LQEMKD---------------------RSAGGESSTFNE--------------------- 296

305A1ps         LQEMRD---------------------QSSDSESSSFNE--------------------- 298

304a1m          IAEMR-------------------------RGPGYGFNR--------------------- 302

304a1ps         ISEMK-------------------------SCPGHGFNR--------------------- 302

307a1m          LKS---------------------------LLEDKDVSR--------------------- 314

307a1ps         LKS---------------------------LVEDKDVSR--------------------- 309

307a2pm         ------------------------------------------------------------

307a2pps        LRS---------------------------LKEDQNVSR--------------------- 309

 

                    10B    

                   10A          10C 10D        10E      10F          10G

12a4m           ----KVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPE-KQARLREEVMKVLPNKNS--- 372

12a5m           ----KVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPE-KQARLREEVMKVLPNKDS--- 372

12A4ps          ----KVATVMAMDMLMAGVDTTSSTFTAALLCLAKNPE-KQAILREEVMKVLPEKDS--- 371

12A5ps          ----KVATVMAMDMLMAGVDTTSSTFTAALLCLAKNPE-KQAILREEVMKVLPEKDS--- 371

12c1m           ----KLAVVMAMDMLMGGVDTTSTAISGILLNLAKNPE-KQQRLREEVLSKLTSLHS--- 362

12c1ps          ----KFAVVMAMDLLFGAVDTTTSALAGVLLSLAKNPK-QQQMLREEIVSMLPHPDR--- 371

12e1m           ----QTAVIIAMDLLFAGADPTLVTLGGILFSLSKSPD-KQARLLEEIRGILPNKDS--- 355

12e1ps          ----KTAVIIAMDFLFAGTDPTLVSLVGILLSLAKNPD-KQARLLEEINQILPAKDS--- 358

12d1m           ----KVAVIMSLDILFAGVDATATLLSAVLLCLSKHPD-KQAKLREELLSIMPTKDS--- 364

12d1ps          ----KLALIMGLEILFAGVDATATLLSAVLLTLAKHPE-KQHKLRAEVRQVMPSKES--- 364

12b2m           ----KVAVTMVMDMLMAGIDTTSSACLTILYHLARNPS-KQEKLRRELLRILPTTKD--- 370

12B2ps          ----QVAVVMAMDMLMAGIDTTSSAFVTILYHLACNPS-KQSQLRRELLHILPDSKG--- 373

49A1m           ----KLAAILALDLFLVGVDTTSVAASSTIYQLAKNPD-KQKKLFDELQKVFPHREA--- 428

49A1ps          ----KLAAILALDLFLVGVDTTSVAASSTIYQLAKNPD-KQRRLFEELQRVFPHREA--- 433

301a1m          ----KIATIMALDLILVGIDTISMAVCSMLYQLATRPV-DQQKVHEELKRLLPDPNT--- 399

301A1ps         ----KIATIMALDLILVGIDTISMAVCSMLYQLATRPE-EQQKVHEELKRLLPDPNT--- 404

302a1m          ----SDVVGTAADLLLAGIDTTSYASAFLLYHIARNPE-VQQKLHEEARRVLPSAKD--- 335

302A1ps         ----SDVVGTAADLLLAGIDTTSYASAFLLYHVARHPE-VQQRLHAEARRVLPDPDQ--- 333

314a1m          ----RDKKSAIIDFIAAGIETLANTLLFVLSSVTGDPG-AMPRILSEFCEYRDTN----- 385

314a1ps         ----RDKKSAIIDFIAAGIETLANTLLFVLSSVTEEPS-AMTRILSEFCEYRDTN----- 386

315a1m          ----DMIKRIFVDLVIAAGDTTAFSSQWALFALSKEPR-LQQRLAKERATND--S----- 376

315a1ps         ----EMIKRIFVDLVIAAGDTTAFSSQWALFVLSREPQ-LQSRLARERVASE--S----- 378

6a2m            ----GELAAQVFVFYVAGFETSSSTMSYCLYELAQNQD-IQDRLRNEIQTVLEEQE---- 348

6a2ps           ----GELAAQVFVFYLAGFETSSSTMSYCFYELAQHQD-IQDKLRSEVLTVLAEHD---- 348

6a8m            ----EEVLAQAFVFFIAGFETSSSTMGFALYELAKNPD-IQDKVRAEVEEVIEQHD---- 348

6a18m           ----DEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPS-IQDKVRAELGQVLEQHD---- 348

6a8ps           ----DEILAQAFVFLIAGFETSSSTMGYALYELAKQPH-IQDKVRAEVEEVLEQHE---- 347

6a9m            ----EEMAAQAFVFFGAGFETSSTTMGFALYELAQHQD-IQDRVRKECQEVIGKYN---- 346

6a21m           ----EEIAAQAFVFFAAGFETSSTTMGFALYELAQNQD-IQNRVRKECQEVIEKCN---- 346

6a21ps          ----EEIAAQAFVFFAAGFETSSTTMGFALYELAQHPD-IQQRVREECQEVIQKYG---- 348

6a17m           ----NELLAQAFIFFVAGFETSSTTMGFALYELARNQD-VQDKLREEIGNVFGKHN---- 342

6a23m           ----NEILAQAFIFFVAGFETSSTTMGFALYELALDQD-IQDQLRAEINNVLSKHN---- 343

6A17ps          ----NEILAQAFIFFVAGFETSSTTMGFALYELAQNQD-TQDKLRNEINDVLAKHN---- 341

6A23ps          ----NEILAQAFIFFVAGFETSSTTMGFALYELAQNQD-TQDKLRNEINDVLAKHN---- 340

6a20ps          ----NELAAQAFIFFLAGFDTSSTSLGFALHELAVNQD-IQDKLRTEIDTVMAKHN---- 341

6a20m           ----NEIAAQAFIFFLAGFETSSTTMGFALYELACHQD-IQDKLRTEINTVLKQHN---- 353

6a19m           ----NEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQD-VQDKLRAEIDSVLERYN---- 343

6a22m           ----EEMAAQAFIFFAAGFDTSASTLGFALYELAKQPA-LQAKLREEIDQALRLHN---- 336

6A22ps          ----EEMAAQAFIFFAAGFDTSASTLGFALFELARQPQ-LQDKLRQEIDAALQLHQ---- 336

6a13m           ----EQIAAQALVFFLAGFDTSSTTMSFCLYELALNPD-VQERLRVEVLAVLKRNN---- 333

6A13ps          ----EQIAAQAMVFFLAGFDTSSTTMSFCLYELALNPD-VQDRLRSEILEVLAKNN---- 333

6a14m           ----EQMAAQAFVFFVAGFETSSSTMSLCLYELALQPD-IQQRLREEIESVLANVDG--- 362

6A14ps          ----EQMAAQAFVFFLAGFETSSSTMAYCLYELAQHPD-IQRRVREEIDAVLKNVEG--- 343

6a15pm          ----EQMAAQAIVFFLAGFETSSSTMSSCKYELALQPE-INQIR----DEIERVLEG--- 113

6a16m           ----EQMAAQAFVFFVAGFETSSSNMSYALFELAKNQD-VQQKLRMEINDSIGKHG---- 358

6A16ps          ----EQLTAHAFDFFVSGYETSSSTMSCALFELAKHPS-VQQKLRNEITGILHKHAP--- 335

6u1m            ----IEIAGQAFGFVLAGLGPLNATLAFCLYELARQPE-VQDRTRLEINKALEEHG---- 325

6u1ps           ----VQIAAQAFGFVLAGLVPLNATLSFCLYELARQPE-LQDRVRAEIRKTLEQHS---- 327

317a1m          ----NELAAHAVVFLKAGYEQTANTLSYVLYELALHPE-LQVRVREEVKKAIERHD---- 358

317a1ps         ----NELAAHAVVFLKAGYEQTANTLSYILYELAIHTD-VQATVREEIKKAMERHD---- 358

6g1m            ----DFLVAQAGVFFTAGFETSSSTMSFALYEMAKHPE-MQKRLRDEINEALVEGGG--- 351

6G1ps           ----DFLVAQAGVFFTAGFETSSSTMSFALYELAKNSH-LQTRLRQEINEALVEGGG--- 353

6w1m            ----DYLVAQAAVFQTAGFETSASTMTMTLYELAKNEA-LQDRLRQEIVDFFGDED---- 343

6w1ps           ----DYLVAQAAVFQTAGYETSSSTMTLALYEVAKNEE-IQNRLRQEIEEYFGDDD---- 345

6v1m            ----DFLAAQAASFEVAGIETCSASMSFALYELAKQPL-MQSRLRREIREAFASNPN--- 357

6v1ps           ----DFLAAQAASFEVAGIETCSSSLSFALYELAKQPL-MQARLRREIRETFEESPA--- 358

6g2m            ----DILVAQAVLFFTAGFESSSSTMAFAMYELAKDTD-VQQRLREEIKDALVESGG--- 355

6g2ps           ----DILVAQAVLFFTAGFESSSSTMAFAMYELAKDAD-IQLRVRHEIKEALIASGG--- 355

6t1m            ----DFFAAQAAFLLLAGFDTSSSTITFALYELAKNTT-IQDRLRTELRAALQSSQD--- 364

6t2pm           ----DFYVAQAAFLLLAGFDTSS---SFALYELAKNPT-IEHRLQAELRVDLQSSHN--- 324

6t1ps           ----DFFVAQASFLLLAGFDTSSSTITFALYELAKAPA-IQKRLRDELSDALRTNRH--- 368

6t3m            ----DFVASQAGIILLAGFETSSALMGFTLYELAKAPD-IQERLRSELREAFISTAT--- 339

6t3ps           ----DFIASQASIILLAGFETSSALLGFTLYELAKQPD-LQKRLREELAEAFSLAPT--- 340

9b1m            ----DEIVAQCFIFFFAAFENNSNLICTTAYELLRNLD-IQERLYEEVKETQEALKG--- 343

9b2m            ----DEIVAQCFIFFFAAFENNSNLICTTTYELLYNPD-VQERLYEEIVETKKALNG--- 343

9B2ps           ----DEIVAQCFIFFFAAFENNANLICTTSLELLENPD-IQQRLYEEAKEVQESLKG--- 343

9f2m            ----RDIVAQCFVFFFAGFETSAVLMCFTAHELMENQD-VQQRLYEEVQQVDQDLEG--- 356

9f3pm           ----RDIVAQCFVFFFAGFETSAVLMCFTAHELMENQD-VQQRLYEEVQQVDQDLEG--- 356

9F2ps           ----RDIVAQCFVFFFAGFETSAVLMCFTAQELMENED-VQQKLYEEVQQVDIDLDG--- 357

9c1m            ----DDLLAQCLLFFSAGFETVATCLSFTSYELMMNPE-VQEKLLAEILAVKEQLGE--- 358

9c1ps           ----EDLLAQCLLFFSAGFDTVATCLSFTSHELLMNPE-AQDKLYEEIMATEEQLGG--- 361

9h1m            ----DDLLAQCLLFFFAGFEIISSSLCFLTHELCLNPT-VQDRLYEEIISVHEELKG--- 358

9h1ps           ----EDLLAQCLLFFFAGFQIISSALCFLSYELCMNPE-VQSELYSEILSVDRELDG--- 358

6d2m            ----EKIAAQAFLFYVAGSESTAAASAFTLYELSMYPE-LLKEAQEEVDAVLMKHNLKP- 355

6d2ps           ----EKIAAQAFLFYVAGSESTAAAAAFTLYELAMYPE-LLKEARDELDTVLQRHNLEG- 359

6d4m            ----EAITAQAFIFYIAGQETTGSTAAFTIYELAQYPE-LLKRLQDEVDETLAKN----- 355

6d4ps           ----ESITAQAFIFYIAGQETTGSTAAFVLFELAQYPE-LLERLQTEVDETLAKN----- 355

6d5m            ----DLIAGQLFLFYVAGYETTASTTSFTLYELTQNPE-VMEKAKEDVRSAIEKH----- 351

6D5ps           ----DLIAGQLFLFFVAGYETTASTAAYTIYELTQNPE-VMARALEDVRSTLEKH----- 351

310a1m          ----KRLAKVAEDLLKVSLDAVASTVTFTLLEILQEPL-IVEKLRAEIKELSNEN----- 320

310a1ps         ----KRVAKVAEDLLKVSLDSISSNITLTLFEILQEPL-IVEKLQTEIKELSNEN----- 321

28a5m           ----RQLLAYSMTFLLDGFETTATVLAHILLNLGRNKE-AQNLLREEIRSHLQ------- 342

28A5ps          ----RQLLAHTMTFLLDGFETTATVLAHMLLLLGREPE-AQKRLREEILAHVK------- 342

28d1m           ----AELTSHTMTFLTDGFETTAQVLTHTLLFLARNPK-EQMKLREEIG----------- 337

28d1ps          ----TELTSHTMTFLTDGFETTALVLSHTLLLLGRNPA-EQRKVRDEIG----------- 336

28d2m           ----DNILINTMTFILDGFETTALVLAHIMLMLGRNPE-EQDKVRKEIG----------- 336

28c1m           ----EDMASHAMTFMFDGLDTTSNSIAHCLLLLGRNPD-CQRRLYEELQLVNP--G---- 336

28c1ps          ----PQLTSHAMTFMFDGLDTTSSTISHCLLLLGRYPE-CQQRLYEELDKASP--S---- 336

309a1m          ----HDSVGHALTVHLDGFETSGAVLYHMLYSLSEHHE-EQEKLRSEILEALA--S---- 345

309a1ps         ----TDAVGHALTVLLDGYETSAAVLYHMLYTLSEHPE-EQEKLRSELVEALA--A---- 345

309a2m          ----DDLVGHALTVMLDGYDTSGTALLHALYYLAENPA-VQQKLRVEILSCMA--S---- 345

309a2ps         ----DDLVGHALTVMLDGYDTTGTALLHALYYLAENPA-AQQKLRMEILQSLD--A---- 348

308a1m          ----EELAGHATTLLLEGYETSAMLLAFALYELALNED-AQRRLHIELDEVAQRHA---- 325

308a1ps         -----DLAGHATTLLLEGYETSAMLLAFALYELSRNES-AQRRVQTELEEVAQRHG---- 332

4aa1m           ----EDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPE-CQDRCVLELATIFE--DS--- 353

4aa1ps          ----QDIVNEACTFMLAGQDSVGGAVAFTIFLLAQNAE-CQEQCHEELERIFD--YS--- 365

4C3m            ----EDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPE-YQERVVEELDSIFG-DDK--- 380

4C3ps           ----EDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPE-YQEQVAEELDSIFG-NDK--- 379

4d1m            ----LDIREEVDTFMFEGHDTTSSALMFFFYNIATHPE-AQKKCFEEIRSVVG-NDK--- 354

4D1ps           ----LDIREEVDTFMFEGHDTTSSALMFFFYNVATHPE-AQKKCFEEISSVIG-QDK--- 357

4d1malt         ----LDIREEVDTFMFEGHDTTSSALMFFFYNIATHPE-AQKKCFEEIRSVVG-NDK--- 345

4D1psalt        ----LDIREEVDTFMFEGHDTTSSALMFFFYNVATHPE-AQKKCFEEISSVIG-QDK--- 358

4s3m            ----TDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPD-VQQRAFEEASELEG-REK--- 345

4s3ps           ----RDIREEVDTFMFEGHDTTSSAIAFALSLLSKHSE-VQQRAYEEARDLEG-REK--- 346

312a1m          ----KDIREEVDTIIFGGFDLTATTLNFFMYNMTLHPE-HQQRCREEVWSVCG-KDK--- 354

312a1ps         ----KEIREEVDTIIFGGFDLTATVLKFVMYNMTLHTD-HQQQCREEIWQICG-KDT--- 355

4g1m            ----KDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKD-IQAKVFAEQKAIFG-DNM--- 394

4G1ps           ----KDIIDEVNTIMFEGHDTTSAGSSFALCMMGIHKD-IQEKVFAEQKAIFG-DNM--- 390

4g15m           ----TEIKEQVDTIMFEGHDTTAAGSSFFLSLMGIHQD-IQDRVLAELDSIFG-D-S--- 416

4G15ps          ----TEIKEQVDTIMFEGHDTTAAGSSFFLSLMGIHQE-IQDRVIAELDGIFG-D-S--- 416

4d2m            ----EDIREEVDTFMFEGHDTTTSAISFCLYEISRHPE-VQQRLQQEIRDVLG-EDR--- 349

4D2ps           ----DDIREEVDTFMFEGHDTTTSAISFCLYEISRHPQ-VQQLLVEEIHEVLG-VDR--- 353

4d14m           ----DDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPE-VQARVFQEVRDVIG-DDK--- 353

4d14ps          ----EDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPE-VQARVFQEVRDVLG-DEK--- 355

4d8m            ----DEIREEVDTFMFEGHDTTTSALSFCLHELSRHPE-VQAKMLEEIVQVLG-TDR--- 347

4d8ps           ----DEIREEVDTFMFEGHDTTTSALSFCLHVLARHPQ-VQEKMLEEILRVIG-TDR--- 348

4ae1m           ----KQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEA-VQQKLFEELRMHYG-QDL--- 342

4AE1ps          ----KQIRDEVNTFIFEGHDTTTSAISFCLYLLSRHAA-VQERLFDEVKGHFG-REL--- 347

4d20m           ----ADIREEVDTFMFEGDDTTSSGVSHALYAIARHPE-VQQRIFEELQRVLG-PDA--- 354

4D20ps          ----ADIREEVDTFMFEGDDTTSSGVSFALYAIARHPQ-VQARIYRELLQVLG-RDP--- 355

4d21m           ----VDIREEVDVFIFAGDDTTTSGVSHALHAISRHPK-VQECIYEELVSVLG-PDP--- 354

4e2m            ----KELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQD-EQRKLFKEQREVMGNSEL--- 346

4e2ps           ----QELYEEVSTFMFEGHDTTTSGVSFAVFLLSRHKD-EQRKLFDEQREVMGDSGM--- 346

4e1m            ----QELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPD-EQEKLFNEQCDVMGASGL--- 346

4e1ps           ----QELYEEVSTFIFAGHDTTTSAISFTLYLVSRHQDDEQRKLFEEQRDVMGDSGL--- 347

4e3m            ----QEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPD-VQRKLYREQCEVMG-HDM--- 345

4e3ps           ----QEIYEEVSTFMFEGHDTTTSGVAFAGYLLSRHPE-AQQRMYQEQCNVMG-SEL--- 345

4ad1m           ----REIIEEVSTFIFTGHDPIAAAISFTLYTLSRHSE-IQQKAAEEQRRIFG-ENF--- 343

4AD1ps          ----REIIEEISTFIFAGHDPVAAAISFTLYTLSRHTE-IQQRVFEEQQRIFG-QDL--- 344

4p1m            ----IGICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPD-KQELCYQEIQEHIDDD----- 357

4p3m            ----IGICEEVDTLMFEGYDTTSIGLMFGLMNMSLYPE-EQEKCYQEIQANIDDE----- 359

4p1ps           ----AGICEEVDTLMFEGYDTTSIGLIFSLMNMSLYPE-KQELCYKEIEEHIDDS----- 360

4P2ps           ----AGICEEVDTLMFEGFDTTSIGLIFSLMNMSLYPE-KQELCYKELEEHIDDN----- 361

4P3ps           ----AGICEEVDTLMFEGYDVSSITLIFTLMNMSLYPD-KQELCFKEIQEHIEDD----- 361

4p2m            ----IGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAA-EQELCYQEIQEHILDD----- 362

4ac1m           ----QGICDEVNTFMFEGYDTTSTCLIFTLLMLALHED-VQKKCYEEVENLPED------ 353

4AC1ps          ----QGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEE-VQERCLEEVSTLPED------ 353

4ac2ps          ----QGICDEVNTFMFEGYDTTSTCLIFTLLMLSLHKD-VQERCLEEVSALPED------ 354

4ac2m           ----QGICDEVNTFMFEGYDTTSTCLIFTLLMLALHED-VQKKCYEEIKYLPDD------ 354

4ac3m           ----QGICDEVNTFMFGGYDTTSTSLIFTLLLLALHAD-VQERCYEELQDLPED------ 353

311a1m          ----REIRDEINTFVFAGVDTTTAAMSFVLYALAKFPE-TQTRLRKELQDVAL------- 328

311a1ps         ----KEIRDEINTFVFAGVDTTTAAMSFVLYALAMNPE-AQDRLQEELRQLPP------- 277

316a1m          ----EEICGELNTCNYLGYQLCSPALCFCLVTIARNPS-VQQKCLDELNLAQI------- 335

316A1ps         ----DDICAELNTCNYLGYLLCSSALCFSLVTISRHPA-VQQRCLEELRKAQR------- 340

313a2m          ----MELGAECSSMVLAAFETSAHTVYYALVLLAMFPE-HQEMVFNEIKEHFPLAKG--- 336

313a3m          ----EEVQSECCSFVVAAFETTGDTVYHALILLAMFPE-HQDTVYQELKELFPVAGD--- 336

313a1m          ----MDVKSECCIMIAAGYDTSALTVYHALFLLANHPE-HQEAVFEELNGVFPDAGH--- 336

313C1ps         ----EDVKSECILTIVAGFETSAITVFNTLILLAMFPE-YQETAFEELKDVFPHVGD--- 337

313C2ps         ----EDAEGECSIMVGASFETTAVTVFSTLTFLAMFPE-YQDAAFVELKDVFPNAGD--- 337

313a5m          ----DDVMGEFSNIIFAASDTLSITVNNVLILMAMFPK-YQDNVFEELAEVFPSGGE--- 331

313a4m          ----KNVEDESNIIVFGAFETTANAVYYTLMLLAMFPE-YQERAFEEIKTIFPNTGD--- 338

313a4ps         ----KNVEDESNIIVFGAFETTANTVYYVLMLLAMFPQ-YQERAFEEIKSLFPNSGD--- 335

313A4bps        ----TNVEDESNQVVFGAFETTAKTVYYVLMLLAMFPQ-YQEKVFEEIKSLFPDSGD--- 333

313b1m          ----QDVRDEANVTIAATFETTSTALYFTILCLAMHPC-YQEKLHKELVTELPPSG---- 345

313b1ps         ----QDVRDEANVTIAATFETTSTALYFTILCLAMHPT-YQEKLHKELVAELPPNG---- 344

318a1m          ----EEIMDEAQSMVLVSFETVSNSIMLALLCLATNKGDCQRRLLAEIRALVPDVG---- 354

318A1ps         ----QEIEDEAQSMVLVSFETVSNSIMLALLCLATHKGDCQQRLRAEIASVFPGQGQGST 356

18a1m           KNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPK-EMRRVQDELDQVVGRH----- 365

18a1ps          KNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPK-EMRRVQDELDQVVGRH----- 366

306A1m          LYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQR-CQRRLHELLLPLG-------- 404

306A1ps         LYCDEQLRHLLADLFGAGVDTSLATLRWFLLYMAREQS-SQRRLHELLLPLS-------- 422

303a1m          ----QSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPE-IQERAFQEIKEVVGLE----- 347

303A1ps         ----ESLLAICLDMFLAGSETTNKSLGFCFMHLVLRPD-IQERAYTEIKEVVGLE----- 347

305a1m          ----TQLVMTILDFFIAGSQTTSNTINLALMVLAMRPD-VQEKLFSQVTASVAAA----- 346

305A1ps         ----TQLVMTILDFFIAGSQTTSNTINLALMVLAMRSD-VQEKLFAEVSANVNSA----- 348

304a1m          ----DQLIMGLVDFSFPAFTAIGVQLSLLVQYLMLYPA-VLRRVQNEIDEVVGCG----- 352

304a1ps         ----DQFIMGLLDFSIPAFTAVGVQLTLLIQYLMLYPS-VMERIQQEIEEVVGCG----- 352

307a1m          ----N-TIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVD-IGRRIQEEIDAIIEEE----- 363

307a1ps         ----N-TIIFMLEDFIGGHSAVGNLVMLALAYIAKNPQ-VGRRIQDEVDAVSSKG----- 358

307a2pm         ------------------------------------------------------------

307a2pps        ----N-TIIFMLEDFIGGHSAVGNLVMLALAYIAKNPM-IGRRIEHEADIVTNKG----- 358

 

                                            11C

                        11A              11B               11D  11E

12a4m           ---E-FTEASM---KNVPYLRACIKESQRLHP-LIVGNARVLARDAVLSG-- 414

12a5m           ---E-FTEASM---KNVPYLRACIKESQRVYP-LVIGNARGLTRDSVISG-- 414

12A4ps          ---E-FTEASM---KNVPYLRACIKESQRLYP-LVIGNIRVLNRDSVLSG-- 413

12A5ps          ---E-FTEASM---KNVPYLRACIKESQRIYP-LVIGNGRVLNRDSVLSG-- 413

12c1m           ---E-FTVEDM---KSLPYLRAVIKESLRLYP-VTFGNARSAGADVVLDG-- 404

12c1ps          ---Q-FTLAEM---KSLPYLRACIKESMRMFP-VTFGNIRSAGTDVVLDG-- 413

12e1m           ---S-LTIENM---RNLPYLRACIKEGIRMYP-IGPGTLRRMPHDVVLSG-- 397

12e1ps          ---P-LTIENM---SNLPYLRACIKEGIRLYP-IGPGTVRRMPHDVVLSG-- 400

12d1m           ---L-LNEENM---KDMPYLRAVIKETLRYYP-NGLGTMRTCQNDVILSG-- 406

12d1ps          ---L-LNEDTM---RDMPYLRAVIKETLRFYP-NGLGTLRSCPTGVTLSG-- 406

12b2m           ---S-LTDQNT---KNMPYLRACIKEGLRITS-ITPGNFRITPKDLVLSG-- 412

12B2ps          ---S-LTDEST---KNMPYLRACIKEGLRITS-ITPGNFRITTKDLVLSG-- 415

49A1m           ---D-INQNVL---EQMPYLRACVKETLRMRP-VVIANGRSLQSDAVING-- 470

49A1ps          ---E-INQNVL---EQMPYLRACVKETLRMRP-VVIANGRSLQSDAVING-- 475

301a1m          ---P-LTIPLL---DQMHHLKGFIKEVFRMYS-TVIGNGRTLMEDSVICG-- 441

301A1ps         ---P-LTIQLL---DQMHHLKAFIKEVFRMYS-TVIGNGRTLQEDSVICG-- 446

302a1m          ---ELSMDALR---TDITYTRAVLKESLRLNP-IAVGVGRILNQDAIFSG-- 378

302A1ps         ---PLSADALR---TDITYTRAVLKESLRLNP-ISVGVGRVLNQDTVLSG-- 376

314a1m          -----ILQDAL---TNATYTKACIQESYRLRP-TAFCLARILEEDMELSG-- 426

314a1ps         -----ILQDAL---TNATFTKACIQESYRLRP-TAFCLARILEEDMELSG-- 427

315a1m          ----------------R-LMHGLIKESLRLYP-VAPFIGRYLPQDAQLGG-- 408

315a1ps         ----------------Q-LLHGLIKESLRLYP-VAPFIGRYLPQDAHLGD-- 410

6a2m            ---GQLTYESI---KAMTYLNQVISETLRLYT-LVPHLERKALNDYVVPG-- 391

6a2ps           ---GKLTYECV---KEMRYLDQVFSETLRLYT-LVPHLERRALSDYVVPG-- 391

6a8m            ---QNFTYECT---KDLKYLNQVLDETLRLYT-IVPNLDRMAAKRYVVPG-- 391

6a18m           ---QKFTYECI---KDLKYLDQVINETLRHYT-IVPNVDRVAAKRFVVPG-- 391

6a8ps           ---QKFTYEST---KDLKYLEQVIFETLRLHT-IVPHLDRMAHKRYVVPG-- 390

6a9m            ---GEITYESM---KDMVYLDQVISETLRLYT-VLPVLNRECLEDYEVPG-- 389

6a21m           ---GELNYESM---KDLVYLDQVVSETLRLYT-VLPVLNRECLEDYEVPG-- 389

6a21ps          ---GELTYESM---KELVYLDQVISETLRLYT-VLPVLNRECLEDFVVPD-- 391

6a17m           ---KEFTYEGI---KEMKYLEQVVMETLRKYP-VLAHLTRMTDTDFSPE--- 384

6a23m           ---NEFTYEGI---KEMKYLEQVVMETLRKYP-VLAHLTRMTQTDFSPE--- 385

6A17ps          ---NQFTYEGI---KEMKYLEQVVMETLRKYP-ALGHLTRKTRLDFSPE--- 383

6A23ps          ---NQFTYEGI---KEMKYLEQVVMETLRKYP-VLAHLTRKTQADFSPE--- 382

6a20ps          ---GQLNYDSM---RELTYLDKVIDETFRKNP-VVGHLIRICTQRYEHP--- 383

6a20m           ---GKLDYDSM---REMTYLEKVIDETMRKRP-VVGHLIRVATQHYQHT--- 395

6a19m           ---GKLEYDSM---QDLFYMEKVINESLRKHP-VVAHLARIATKPYQHS--- 385

6a22m           ---GEFTYDSM---QELRYMELVIAETLRKYP-ILPQLTRISRHLYAAKG-- 379

6A22ps          ---GQFTYDSM---QELRYMELVIAETLRKYP-PLPHLTRISKNLYTAKG-- 379

6a13m           ---QKLTYDSV---QEMPYLDQVVAETLRKYP-ILPHLLRRSTKEYQIP--- 375

6A13ps          ---HQLTYESI---QEMPYLDQVVAETLRKYP-ILPHIVRQTTKKYDVP--- 375

6a14m           ---GELNYDVL---AQMTYLDQVLSETLRKHP-LLPHLIRETTKDYQIP--- 404

6A14ps          ---GEITYDAL---AEMNYLEKVLAETLRKHP-IVPQLIREANQNYKVP--- 385

6a15pm          ---NAITYDAL---AKINYPEQVLSETLRKH--QLIKFLLETQESFRVR--- 164

6a16m           ----KLTYEAM---MEMPYLDQTITETLRKYP-ALSSLTRLASEDYEIPSPD 402

6A16ps          ----NLTYEAV---QEMRYLDQTITETLRKYP-ALASLTRIAAEDYTVPTAS 379

6u1m            ---GQVTPECL---RELRYTKQVLNETLRLHT-PHPFLLRRATKEFEVPGS- 369

6u1ps           ---GQLTTEGL---KELLYTKQVLNETLRLHT-PYPFLLRRATKEFELPGS- 371

317a1m          ---GHITHEGI---KSLSFMGQVINETLRMHP-ITPYILRRTLNDYAVPDHP 403

317a1ps         ---NNLNYECV---QSLAYLGQVINETLRVHP-ITPYILRRTLTDYQVPDHP 403

6g1m            ----SLSYEKI---QSLEYLAMVVDEVLRMYP-VLPFLDREYESVEGQPDLS 395

6G1ps           ----NLSYEKI---QSLEYLAMVVDEVLRMYP-VLPFLDREYNSIKDQPDLS 397

6w1m            ----HISYERI---QEMPYLSQVVNETLRKYP-IVGYIERECSQPAEGERFT 387

6w1ps           ----HISYERI---QEMPYLSKVVNETLRLYP-IVGYAERECAQPSQGERFT 389

6v1m            ---GRLTYEAV---ARMEFLDMVVEETLRKYP-IVPLLERECTPINKKRFYS 402

6v1ps           ---GSLSYELI---GRMQYLEMIVEETHRKYP-IVPLLERECTPINKKRFYS 403

6g2m            ----QVTLKMI---ESLEFMQMILLEVLRMYP-PLPFLDRECTS--GRDYSL 397

6g2ps           ----QVTLQLI---DSLEYMQMVLLEVLRMYP-PLPFLDRECTA--EDEDYS 397

6t1m            ---RQLSCDTV---TGLVYLRQVVDEVLRLYP-PTAFLDRCCNSRTGYDLSP 409

6t2pm           ---HQLSYDTL---TGLVYLRQVLEDLP------------------------ 346

6t1ps           ---QPLNFDSV---NGLSYLRQVVDEVLRLYP-PTAFLDRCCNDENGYDLSA 413

6t3m            -----LSYDTL---MTLPYLKMVCLEALRLYP-AAAFVNRECTSSASEGFS- 381

6t3ps           -----LTYETL---VTLPFLRKVCLEALRLYP-AAAFINRECTSSDPNGFS- 382

9b1m            ---APLTYDAA---QEMTYMDMVISESLRKWT-LSAAADRLCAK--DYTLTD 386

9b2m            ---APLTYDAV---QKMTYMDMVISESLRKWT-LAAATDRLCSK--DYTLTD 386

9B2ps           ---SSLTYDAV---QKMKYMDMVISESLRKWT-LAPVTDRICSK--DYTLTD 386

9f2m            ---KELTYEAI---MGMKYLDQVVNEVLRKWP-AAIAVDRECNK--DITFDV 399

9f3pm           ---K-----------ELKYLDQVVSEVLRKWP-PAIAFDRECN--------- 384

9F2ps           ---KELSYEAI---MGMKYLDQVVSEVLRKWP-AAIAIDRECNK--DITYEL 400

9c1m            ---KPLDYDTL---MGMKYLNCVVSESLRKWP-PAFIVDRMCGS--DFQLKD 401

9c1ps           ---KPLDYDTL---MGMKYMDCVVSESLRMWP-PAFVLDRMCGS--DFELRD 404

9h1m            ---QPLTYDKL---TKMKYLDMVVLEALRKWP-PSISTDRECRQ--DIDLFD 401

9h1ps           ---KPPTFDRL---TRMKYLDMVVQEGLRKWP-PSIATDRECNN--DIDLCD 401

6d2m            --KDRFTYEAV---QDLKFLDICIMETIRKYP-GLPFLNRECTEDYPVP--- 398

6d2ps           --TGKLTYEAV---HDLKFLDLCLKETLRKYP-GLPFLNRECTEDYLVP--- 402

6d4m            --DGKITYDSL---NKMEFLDLCVQETIRKYP-GLPILNRECTQDYTVP--- 398

6d4ps           --DGHITYDAL---QKMEFLDLCVQESLRKYP-GLPMLNRECTQDYTVP--- 398

6d5m            --GGKLTYDAI---SDMKYLEACILETARKYP-ALPLLNRICTKDYPVP--- 394

6D5ps           --DGKLSYDAI---QDMKYLEACVLETARKYP-ALPLLNRVCTKEYQIP--- 394

310a1m          ---GQLKFEEL---NGLRYMDMCLKETLRKYP-PLPIIERVCRKSYSLP--- 362

310a1ps         ---GSLKFEEL---DGLKYLDMCLKETVRKYP-PLPIIERICRKSYTLP--- 363

28a5m           --DGTIAFEKL---SDLPYLDACVQETIRLFP-PGFMSNKLCTESIEIP-NK 387

28A5ps          --DGIVSFEKL---NELPFLDACVQETIRIFP-PAFMSNKLCTEAIELP-NK 387

28d1m           --TAELTFEQI---SELPFTEACIHETLRIFS-PVLAARKVVTEPCELT-NK 382

28d1ps          --KGDLTFEQL---SELPYIDACIHETLRLFA-PLLSGRKLVTEAYDFV-NK 381

28d2m           --SADLTFDQM---SELPHLDACIYETLRLFS-PQVAARKLVTEPFEFA-NK 381

28c1m           --GYLPDLDAL---IDLPYLSACFNESLRIYP-AGGWASKTCTKEYELRGSH 382

28c1ps          --KELPDLDAL---NDLPYLSACFNESLRIYP-AGGWASKTCTEPYKLHGSH 382

309a1m          --EGQISYDQI---NNLPYLDQCFNESLRLTT-PIGFFMRICTKPTQIN-LG 390

309a1ps         --DEHLSYEQL---NALPYLDQCLNESLRLTT-PIGFFMRICTKATQLD-LG 390

309a2m          --EKSLDFEKL---SSLQYLEQVIYESLRLSS-LIPQYTKVCTLPTVIR-LS 390

309a2ps         --DKSLGFEKL---CALPYLEQVVYESLRLSS-LIPQYTKICTNATQIQ-LN 393

308a1m          --GNLIDPVAL---GELRYSEAALLEALRLHP-AMQALQKRCTKTFTLPDQK 371

308a1ps         --GLLVGHAAL---AELRYAEAALLETLRLHP-AMQALQKRCTKSFTLPPQR 378

4aa1m           --NRAPTMTDL---HEMRYMEMCIKEALRLYP-SVPLIARKLGEEVRLAK-- 397

4aa1ps          --DRAPTMSDL---REMRYLEMCIKEALRLYP-TVPLIARKLGEEVRLSD-- 409

4C3m            --ETPATMKNL---MDMRYLECCIKDSLRLFP-SVPMMARMVGEDVNIGG-- 424

4C3ps           --ETPATMKNL---MDMRYLECCIKDSLRLFP-SVPMMARMVGEDVNIGG-- 423

4d1m            --STPVSYELL---NQLHYVDLCVKETLRMYP-SVPLLGRKVLEDCEING-- 398

4D1ps           --STPVTYELL---NKLHYVDLCIKETLRMYP-SVPLLGRRVVEECEING-- 401

4d1malt         --STPVSYELL---NQLHYVDLCVKETLRMYP-SVPLLGRKVLEDCEING-- 389

4D1psalt        --STPVTYELL---NKLHYVDLCIKETLRMYP-SVPLLGRRVVEECEING-- 402

4s3m            --------------ESMPYLEAVIKETLRIYP-SVPFFSRKVLEDLEVGK-- 380

4s3ps           --------------ESMPYLEAIIKETLRLYP-SVPFFSRKVFEDIQVGK-- 381

312a1m          --SEPISIEQV---RQLEFLEACIKETLRMYP-SGPLTARKATANCTIND-- 398

312a1ps         --KEPITIEQV---QQLEFLEWCVKETLRMYP-PAPLLTRRATANCQIND-- 399

4g1m            --LRDCTFADT---MEMKYLERVILETLRLYP-PVPLIARRLDYDLKLASGP 440

4G1ps           --LRDCTFADT---NEMKYLERVILETLRLYP-PVPLIARRLDYDLKLASGP 436

4g15m           --QRPATFQDT---LEMKYLERCLMETLRMYP-PVPLIARELQEDLKLNSGN 462

4G15ps          --QRPATFQDT---LEMKYLERCLMETLRMYP-PVPLIARELQEDLKLNSGD 462

4d2m            --KSPVTLRDL---GELKFMENVIKESLRLHP-PVPMIGRWFAEDVEIRG-- 393

4D2ps           --HRPVTLRDL---GELKYLENVIKESLRLHP-PVPMIGRWFNEDVEIRG-- 397

4d14m           --SAPVTMKLL---GELKYLECVIKESLRLFP-SVPIIGRYISQDTVLDG-- 397

4d14ps          --DAPVNIQLL---GELKYLECVIKESLRLFP-SVPIIGRHIVEDTLLDG-- 399

4d8m            --SRPVSIRDL---GELKYMECVIKESLRMYP-PVPIVGRKLQTDFKYTHSV 393

4d8ps           --KRPVTIRDL---NEMKYLECVIKESLRLYP-PVPLVGRKLQTDFKYSHSK 394

4ae1m           --FRGVILSDF---ATLPYLSCVVKESLRLYP-PIPAVARCLEKDLVIDE-- 386

4AE1ps          --DRCVVYSDF---AALPFLNCVVREALRLYP-PIPALGRCLETDLAVEG-- 391

4d20m           --SAPVTQAQL---QDLKYLDCVIKETMRLYP-PVPAIGRHAQKELEIGD-- 398

4D20ps          --STPVTQAKL---QELKYLDCVIRETLRLYP-AVPAVGRYTSKEIQIGG-- 399

4d21m           --DASVTQTKL---LELKYLDCVIKETMRLHP-PVPILGRYIPEDLKIGE-- 398

4e2m            --GRDATFQEI---SQMKYLDLFIKEAQRVYP-SVPFIGRFTEKDYVIDG-- 390

4e2ps           --DRDATFQEI---SEMKYLDLFIKEAQRVYP-SVPFIGRYTEKDYIIEG-- 390

4e1m            --GRDATFQEI---STMKHLDLFIKEAQRLYP-SVPFIGRFTEKDYVIDG-- 390

4e1ps           --DREATFQEI---SEMKYLDLFIKEAQRVYP-SVPFVGRYTEKDYVIDG-- 391

4e3m            --NRSVSFQEI---AKMKYLDLFIKEAQRVYP-SVPFIGRYCDKDYDING-- 389

4e3ps           --DRDATFQEI---AQMKYLDLFIKEAQRVYP-SVPMIGRYADKDYMING-- 389

4ad1m           --AGEADLARL---DQMHYLELIIRETLRLYP-SVPLIARTNRNPIDING-- 387

4AD1ps          --TAEADIGRL---DQMRYLELVIRETLRLYP-SVPLIARTNRKPIDING-- 388

4p1m            --LSNLDVGQL---NKLKYLEYFMKETTRLFP-SVPIMGREAVQETELAN-- 401

4p3m            --LNILNIGQL---NKLKNLEYFIKETMRLFP-SVPAMGRETTRETELSN-- 403

4p1ps           --FDNLDNNQL---SKLKYLEYFIKETMRLFP-SVPIMARQTIQETELAN-- 404

4P2ps           --FDNLDHNQL---SKLKYLEYFIKETMRLFP-SVPIMARQTIQETELAN-- 405

4P3ps           --FSNLDINQM---SKLKYLEYFIKETMRLFP-PIPLMGRQAVQETELAN-- 405

4p2m            --LSNLNLSQL---SKLNYLGYFIKETMRLYP-SIPIMGRQTLQETELEN-- 406

4ac1m           --SDDISMFQF---NKLVYLECVIKESLRMFP-SVPFIGRQCVEETVVN--- 396

4AC1ps          --TDSISVFQF---NELVFLECVIKESLRMFP-SVPFIGRTCVEECVVN--- 396

4ac2ps          --TDSISVFQF---NELVFLECVIKESLRMFP-SVPFIGRQCTEECVVN--- 397

4ac2m           --SDDISVFQF---NELVYMECVIKESLRLFP-SVPFIGRRCVEEGVVN--- 397

4ac3m           --IDEVSMFQF---NELIHLECVIKESLRLFP-SAPIIGRTCIEESVMN--- 396

311a1m          --DETTDLDAL---NGLPYLEALIKEVLRLYT-IVPTTGRQTTQSTEIGG-- 372

311a1ps         --GISIDLDTL---NELPYLDALLKEVLRLYT-IVPTTGRQTTRSTVIGG-- 321

316a1m          ---KD-QGWDL---EKLNYLDAVLHETMRLYP-PQVIVGRQLKKDFPYN--- 376

316A1ps         ---ED-QSWDV---RRLPYLEAVLLETLRLYP-PQVIVGRHLTEDMPYN--- 381

313a2m          ---IEVTHTDL---QQLVYLDRVLNETLRLMP-SVPFSSRETLEDLRLSNG- 380

313a3m          ---FEVTYDDL---QRMVFLERVVNETLRLIP-SVPFTPRETIRDFRLSSG- 380

313a1m          ---FGITYPDM---QKLDYLERVIKETLRLIP-AIPITARETKNDVRLSNG- 380

313C1ps         ---FEVSYDDL---QKLVYMDRVLNESLRLLP-PLPLIPREVTEDLKLSNG- 381

313C2ps         ---FEVSNDEI---QKLVYLDRVLNESLRLIP-AIPLIARETSQEVKLSNG- 381

313a5m          ---FEASHADL---EKLVKLDRVLHETMRLIP-AVPLLIRQTSHSIQLSNG- 375

313a4m          ---FDVSYADT---QQMVYLDLILNESMRVIP-PVPVVSRQTSQDLKLSNG- 382

313a4ps         ---FEVTYEDT---QQMVYLDLVLNESMRVIP-PVPVVSRQTSQDLTLTNG- 379

313A4bps        ---FEVTYEDT---QQMVYLDLVINESMRVIP-PIPLVSRQTSGDLTLSSG- 377

313b1m          ----DINLEQL---QRLEYTEMVINEAMRLFA-PVPMVLRSADQDIQLKRGD 389

313b1ps         ----NISLDQL---ERLSYTEMAINEAMRLFA-PVPMVLRSAAQDFPLRRDD 388

318a1m          ----QVGLEQL---QQLRYLDAFVSESLRLLA-TVPMNLRHVSRDFRLAGRQ 398

318A1ps         SDAPHVGLEQL---QQLRYLDAFVSEALRLLA-TVPMNLRHVSRDFQLPG-- 402

18a1m           ---RLPTIEDL---QYLPITESTILESMRRSSIVPLATTHSPTRDVELNG-- 409

18a1ps          ---RLPTIEDL---QYLPVTESTILESMRRSSIVPLATTHSPTRDVELNG-- 410

306A1m          ---PSPTLEEL---EPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGD-- 448

306A1ps         ---ATPTLEEL---QPLAFLRACISEVQRIRSVVPLGIPHGAERDFTVGK-- 466

303a1m          ---RIPEWSRD--RTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSG-- 392

303A1ps         ---RIPEWTRD--RSKMPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLAG-- 392

305a1m          ---STDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGG-- 393

305A1ps         ---KSDAFPHLSRRESFDYMDAFIMEVQRFFHITPITGPRRALWPTQLGG-- 395

304a1m          ---RLPNLEDR---KNLPFTEATIREGLRIETLVPSDVPHKALEDTELLG-- 396

304a1ps         ---RLPTLEDR---KNMHYTEATIRESMRIETLVPSDVPHKALADTELLG-- 396

307a1m          ---NRSINLLD--MNAMPYTMATIFEVLRYS--SSPIVPHVATEDTVISG-- 406

307a1ps         ---QRKINLLD--MHQMPYTMATIFEVLRYS--SSPIVPHVATEDLVISG-- 401

307a2pm         ----------------------------------------------------

307a2pps        ---RRRINLYD--MDAMPYTMATIFEVLRYSS--SPIVPHVAMEDTAIAG-- 401

 

                                 12B

                                12A          12C 12D              12E   12F

12a4m           ------------YRVPAGTYVNIVPLNALT-RDEYFPQ-ASEFLPERWLRSPKDSESKCP 460

12a5m           ------------YRVPAGTIVSMIPINSLY-SEEYFPK-PTEFLPERWLRNASDSAGKCP 460

12A4ps          ------------YQVPAGTFISMVPTSLLS-SEEHFLK-ANEFLPERWMRSATDSTGECP 459

12A5ps          ------------YQVPAGTCVSMIPLRLLS-SEEHFPK-AAEFLPERWIRNATDSSGVCP 459

12c1m           ------------YRIPKGTKLLMTNSFLLK-DDRLYPR-AKEFIPERWLRRKDDDKSDVL 450

12c1ps          ------------YRIPQGTNLLMLSSNMLR-DERFYPR-PNEFLPERWARPQDDNSAESP 459

12e1m           ------------YRVVAGTDVGIAANYQMANMEQFVPK-VREFIPERWLRDESNSHLVG- 443

12e1ps          ------------YRIVAGTDVAIAANYQMANMEEYVPR-VREFLPERWLRDESNSKLVG- 446

12d1m           ------------YRVPKGTTVLLGSNVLMK-EATYYPR-PDEFLPERWLRDPETGKK--- 449

12d1ps          ------------YAVPPGTTVLLAANALMK-DPAHYPR-PDEFLPERWLRDPQSGQK--- 449

12b2m           ------------YQVPRGTGVLMGVLELSN-DDKYFAQ-SSEFIPERWLKSDLAPDIQAC 458

12B2ps          ------------YQVPRGTGVLMGVMELSN-SDEYFAQ-SADFIPERWLKADLAGDVLAC 461

49A1m           ------------YHVPKGTHVIFPHLVVSN-DPAYFPE-PKRFLPERWLKQSTD-AAGCP 515

49A1ps          ------------YHVPKGTHVIFPHLVVSN-DPAYFPE-PKRFLPERWLKQTAAVAVGCP 521

301a1m          ------------YQVPKGVQAVFPTIVTGN-MEEYVTD-AATFRPERWLKPQHGGTP--- 484

301A1ps         ------------YQVPKGVQAVFPTIVTGN-MEEYVTD-AATFRPERWLKPQHGGVP--- 489

302a1m          ------------YFVPKGTTVVTQNMVACR-LEQHFQD-PLRFQPDRWLQ------HRS- 417

302A1ps         ------------YFVPKGTTVVTQNMIACR-LEQHFPD-PLLFQPDRWLQ------QRN- 415

314a1m          ------------YSLNAGTVVLCQNMIACH-KDSNFQG-AKQFTPERWIDPATENFTVN- 471

314a1ps         ------------YSLNAGTVVLCQNMIACH-KDSNFQE-AKQFSPERWIDPVTENFTVN- 472

315a1m          ------------HFIEKDTMVLLSLYTAGR-DPSHFEQ-PERVLPERWCIGETEQ----- 449

315a1ps         ------------HFVEKDTLVLLSLYTAGR-DASHFEQ-PERVLPERWCVGR-------- 448

6a2m            ---------HEKLVIEKGTQVIIPACAYHR-DEDLYPN-PETFDPERFSPEKVAAR---- 436

6a2ps           ---------HPDLVIEKDTQIIIPACAYHR-DENLYPD-PLRFDPDRFSAEQVAAR---- 436

6a8m            ---------HPNFVIEAGQSVIIPSSAIHH-DPSIYPE-PFEFRPERFSPEESAGR---- 436

6a18m           ---------NPKFVIEAGQSVIIPSSAIHH-DPSIYPE-PNEFRPERFSPEESAKR---- 436

6a8ps           ---------HPNFVIEAGQSVIIPASAIHV-DPNIYPD-PYKFRPERFSPEESAKR---- 435

6a9m            ---------HPKYVIKKGMPVLIPCGAMHR-DEKLYAN-PNTFNPDNFSPERVKER---- 434

6a21m           ---------HPKYVIKKGMPVLIPCGAMHR-DEKLYAN-PNTFNPDNFSPERVKER---- 434

6a21ps          ---------NPKYVIKKGMPILIPAGAMHR-DERFYPN-PDAFNPDNFSPERVKNR---- 436

6a17m           ---------DPKYFIAKGTIVVIPALGIHY-DPDIYPE-PEIFKPERFTDEEIAAR---- 429

6a23m           ---------DPKYFIAKGTTVVIPALGIHY-DPEIYPE-PEKFKPERFTDEAIAAR---- 430

6A17ps          ---------DPKNFIAKGTTVVIPALGIHY-DPDIYPE-PEKFKPERFTEEAIASR---- 428

6A23ps          ---------DPKTFIAKGTVVVIPALGIHY-DPDIYPE-PEKFKPERFTEEAIASR---- 427

6a20ps          ---------NGKYFIEPGTGVVIPTLGIHH-DPEFYPE-PEKFKPERFDEDQVLQR---- 428

6a20m           ---------NPKYNIEKGTGVIVPTLAIHH-DPEFYPE-PEKFIPERFDEDQVQQR---- 440

6a19m           ---------NPKYFIEAGTGVLVSTLGIHH-DPEFYPE-PEKFIPERFDEEQVKKR---- 430

6a22m           ---------DRHFYIEPGQMLLIPVYGIHH-DPALYPE-PHKFIPERFLADQLAQR---- 424

6A22ps          ---------NRHFYIEPGQMLLIPVYGIHH-DPAIYPE-PHKFIPERFMGDQLAQR---- 424

6a13m           ---------NSNLILEPGSKIIIPVHSIHH-DPELYPD-PEKFDPSRFEPEEIKAR---- 420

6A13ps          ---------DSRLTLEPGMRVMIPVHSIQH-DPELYPE-PENFDPSRFEPDQVKAR---- 420

6a14m           ---------NSDIVLDKGILALIPVHNIHH-DPEIYPE-PEKFDPSRFDPEEVKNR---- 449

6A14ps          ---------NTDITIDKGTTVLIPVHSIHH-DPEIYPQ-PESFAPSRFEADQVKSR---- 430

6a15pm          ---------NTELIVEKGTSLLIPVHSVHY-DPHLYPH-PKLFDSSRLKAYKSNSR---- 209

6a16m           G--------GDPVVLEKGTSVHIPVLAIHY-DPEVYPE-PHEFRPERFAPDACRER---- 448

6A16ps          G--------DIPLVLDKGTIVHIPVRAIHY-DSEIYPE-PTIFRPERFETSTCLQR---- 425

6u1m            -----------VFVIAKGNNVLIPTAAIHM-DPGIYEN-PQRFYPERFEEQARRSR---- 412

6u1ps           -----------VFVIARGNNVLIPTAAIHR-DPAIYEE-PLRFDPDRFETEAKRTR---- 414

317a1m          -----------KYILVKELFLIIPTHAIHH-DPDIYPD-PEEFKPDRWSGPRDSLQ---- 446

317a1ps         -----------TYMLVKELFLIIPTHAIHH-DPDIYPE-PEEFKPDRWGGPRDSLQ---- 446

6g1m            LKP------FYDYTLENGTPVFIPIYALHH-DPKYWTN-PSQFDPERFSPANRKNI---- 443

6G1ps           LKP------YYDFTFEHGTPVFIPIYGLQH-DPKYWPK-PEQFDPERFSPENRKSI---- 445

6w1m            LEP------FHNMELPHGMSIYMSTVAVHR-DPQYWPD-PEKYDPERFNSSNRDNL---- 435

6w1ps           LAP------HHDMELPDGTPVYVSAVAIQR-DPKHWPE-PEKFDPERFDASNRDKL---- 437

6v1m            LRP------HAECYTRRGMPVFISNLAIHH-DPKYWPD-PDRFDPERFSAANKALQ---- 450

6v1ps           LRP------HAECYARRGMPIYISNLAIHH-DPKYWPD-PERFDPERFSAENKSHQ---- 451

6g2m            APF------HKKFVVPKGMPVYIPCYALHM-DPQYFPQ-PRKFLPERFSPENRKLH---- 445

6g2ps           LTP------YHGFRVPKGMPIYIPCYALHM-DPQYFPQ-PRKFQPERFSPTNRKLQ---- 445

6t1m            WNG------GSPFKLRAGTPVYISVLGIHR-DAQYWPN-PEVFDPERFSAEQRQQH---- 457

6t2pm           ------------------------------------------------------------

6t1ps           WNC------GRALKLPAGAPVYISVLGLHR-DPVHWPN-PNQFDPEHFSPEQREQH---- 461

6t3m            LQP------HVDFIVPPGMPAYISILGLHR-DERFWPE-PCVFDPERFGPERSRHI---- 429

6t3ps           LQP------HVDFVVPNGMPAYISILGLHR-DEKYWPE-PNRFDPERFDPDRSKDI---- 430

9b1m            DEG------TKLFEFKAGDNINIPICGLHW-DERFFPQ-PQRFDPERFSERRKKDL---- 434

9b2m            DDG------TKLFDFKVGDRINIPISGLHL-DDRYFPE-PRKFDPDRFSEERKGDM---- 434

9B2ps           DDG------TKLFDFKVGDRVNIPIAGLHW-DDKYFPE-PQKFDPERFSDERKNEI---- 434

9f2m            DG--------QKVEVKKGDVIWLPTCGFHR-DPKYFEN-PMKFDPERFSDENKESI---- 445

9f3pm           ------------------------------------------------------------

9F2ps           DG--------QTIEIKKGDYIWLPTCGFHR-DPKYFEN-PNKFDPERFSEENKANI---- 446

9c1m            EEG------EVVVNLREDDLVHINVGALHH-DPDNFPE-PEQFRPERFDEEHKHEI---- 449

9c1ps           EEG------KVVLTLKKDELINIPVIALHH-DPDNFPQ-PDEFRPERFDDDHKHEI---- 452

9h1m            ENG------QKLFSARKGDVLQIPIFSLHH-DPENFED-PEFFNPERFADGHALES---- 449

9h1ps           ESG------EKLFSAKKGDVLQIPIFPLHH-DPENFAE-PERFDPQRFSDERRDEI---- 449

6d2m            ---------GTNHIIAKGTPILISLFGMQR-DPVYFPN-PNGYDPHRFDSNNMNYD---- 443

6d2ps           ---------GTRHTITKGTPILISLFGIHR-DPVYFPN-PEGYDPHRFDADKMNYD---- 447

6d4m            ---------DTNHVIPKGTPVVISLYGIHH-DAEYFPD-PETYDPERFSEESRNYN---- 443

6d4ps           ---------DTDHVIPKGTPVVISLYGIHH-DAEYFPE-PETYDPDRYSEENRNFS---- 443

6d5m            ---------DSKLVIQKGTPIIISLIGMHR-DEEYFPD-PLAYKPERYLENGKDYT---- 439

6D5ps           ---------NSKLIVKKGTPIIISLIGMHR-DAENFPD-PLAYKPERYLDENKNFN---- 439

310a1m          ---------NSKFTIDEGKTLMVPLLAMHR-DEKYFSE-PMKYKPLRFLQTANDVGQC-- 409

310a1ps         ---------NTKFTIDEGKTLMVPLLAIHR-DEKYFSE-PMKYKPLRFLHSEKSG----- 407

28a5m           E--------GPNFVVEKGTTVVVPHYCFML-DEEFFPN-PQSFQPERFLEPDAA------ 431

28A5ps          D--------GPNFTVEVGTTIVIPHYCFML-DEDYFPD-SQSFQPDRFMEPDAA------ 431

28d1m           N--------GVSVKLRPGDVVIIPVNALHH-DPQYYEE-PQSFKPERFLNINGG-A---- 427

28d1ps          N--------GVTVRVHPGDVVIIPAHSMHH-DPEYYED-PEVFKPERFLEINGG-V---- 426

28d2m           N--------GRTVHLKPGDVVTIPVKALHH-DPQYYED-PLTFKPERFLESNGGGM---- 427

28c1m           H--------SEPLKLRPGDHVMVPIYALHN-DPDLYPE-PDVFRPERFLDGG---L---- 425

28c1ps          H--------SQPLQMLPGDNIMIPIYGLHH-DPQFYPE-PEEFRPERFLDGG---L---- 425

309a1m          D--------DKTLDLEPGVTVMVPAYQYHH-DNDIYPE-ASEFRPDRFENGAAS------ 434

309a1ps         Q--------GQVADIEPGASVMIPAYQFHH-DDAFYPE-ASLFQPDRFENGAAS------ 434

309a2m          E--------SKSLDVEVGMTIMIPNYQFHH-DKQYFPE-PEAFKPERFDNGAYQ------ 434

309a2ps         E--------SKTLEVEEGMTVMIPNYQFHH-DRKYFPD-PETFKPERFDDAAHL------ 437

308a1m          S------GASSELKVHLGTVLVLPVQAIHL-DPALYPA-PNQFRPERFLNQP-------- 415

308a1ps         SDTDTAVGSHGSIQVALGTVLVLPVQAIHM-DPNLYSD-PLKFQPERFMDTS-------- 428

4aa1m           ------------HTLPAGSNVFICPYATHR-LAHIYPD-PEKFQPERFSPENSEN----- 438

4aa1ps          ------------HTLPAGSNIFICPYATHR-LNNIYPE-PEKFNPERFSPENSKD----- 450

4C3m            ------------KIVPAGTQAIIMTYALHR-NPRVFPK-PEQFNPDNFLPENCAG----- 465

4C3ps           ------------KLVPAGTQAIIMTYALHR-NPRVFPK-PEQFNPDNFLPENCAG----- 464

4d1m            ------------KLIPAGTNIGISPLYLGR-REELFSE-PNIFKPERFDVVTTAE----- 439

4D1ps           ------------KRIPAGTNIGISPLYLGR-REELFSE-PNSFKPERFDVVTSAE----- 442

4d1malt         ------------KLIPAGTNIGISPLYLGR-REELFSE-PNIFKPERFDVVTTAE----- 430

4D1psalt        ------------KRIPAGTNIGISPLYLGR-REELFSE-PNSFKPERFDVVTSAE----- 443

4s3m            ------------LTVPKGASISCLIYMLHR-DPKNFPD-PERFDPDRFLVN--EK----- 419

4s3ps           ------------HTIPKGASVNCLIYMLHR-DCNNFPD-PERFDPDRFYLN--EK----- 420

312a1m          ------------FFIPKGSDVIISPIYMGR-CKDFFPD-PMVFKPDRWAIG-AEP----- 438

312a1ps         ------------FFIPKGNDVVISPMYMGR-CKDFFPE-PLVFKPERWARG-AEP----- 439

4g1m            ------------YTVPKGTTVIVLQYCVHR-RPDIYPN-PTKFDPDNFLPE-RMA----- 480

4G1ps           ------------YTVPKGTTVIVLQYCVHR-RADIYPN-PTKFDPDNFLPE-RMA----- 476

4g15m           ------------YVIPRGATVTVATVLLHR-NPKVYAN-PNVFDPDNFLPE-RQA----- 502

4G15ps          ------------YVIPRGATVTVATVLLHR-NPKVYTN-PNVFDPDNFLSE-RQA----- 502

4d2m            ------------KHIPAGTNFTMGIFVLLR-DPEYFES-PDEFRPERFDA-DVP------ 432

4D2ps           ------------KRIPAGTNYTVGIFVLLR-DPEYFES-PDEFKPDRFDS-TSP------ 436

4d14m           ------------KLIPADSNVIILIYHAQR-DPDYFPD-PEKFIPDRFSM-ERKG----- 437

4d14ps          ------------KLIPAKTDVMILIYHSQR-DPDYFPE-PNKFVPERFSP-ERKG----- 439

4d8m            H---------GDGVIPAGSEIIIGIFGVHR-QPETFPN-PDEFIPERHEN-GSR------ 435

4d8ps           Y---------GDGVIPAGSEFLIGIYGMQR-NKNEFAQ-SEEFIPERHEN-GER------ 436

4ae1m           ------------GYIPVGTNVVVLLWQLLR-DEAIFTD-PLVFQPERHLG-EEAP----- 426

4AE1ps          ------------GRIPAGTNVILLLWQLLR-DEMLFAD-PLIFRPERHLSNKATS----- 432

4d20m           ------------KTIPANTSIYLVLYYAHR-DANYFPD-PLSFRPERFLEDQE-Q----- 438

4D20ps          ------------QTIPANTSIYLVLYFAHR-EAEFFPD-PLAFKPERFLDRADSE----- 440

4d21m           ------------ITIPGNTSILLMPYYVYR-DPEYFPD-PLVFKPERWMDMKTTS----- 439

4e2m            ------------DLVPKGTTLNLGLVMLGY-NEKVFKD-PHKFRPERFELEKPGP----- 431

4e2ps           ------------DLVPKGTTLNLALVMLGY-NDRVFKD-PHKFRPERFELEKPGP----- 431

4e1m            ------------DIVPKGTTLNLGLLMLGY-NDRVFKD-PHKFQPERFDREKPGP----- 431

4e1ps           ------------DLVPKGTTLHMGIFMLGY-DDRVFKE-PHKFRPQRFEEEKPGP----- 432

4e3m            ------------SIVPKGTTLNLALILLGY-NDRIFKD-PHHFRPERFEEEKPAP----- 430

4e3ps           ------------TLVPKGTTINLALVLLGY-NDRIFKD-PHHFRPERFEEEKPGP----- 430

4ad1m           ------------TKVAKCTTVIMCLIAMGY-NEKYFDD-PCTFRPERFENPTGNV----- 428

4AD1ps          ------------TKVAKRTTVIMCLIAMGY-NEKYFEE-PCVFRPERFETAGADV----- 429

4p1m            -----------GLILPKGAQITIHVFDIHR-NAKYWDS-PEEFRPERFLPENVQD----- 443

4p3m            -----------GLILPKGSQIFVHVFDIHR-NPEYWDS-PEEFRPERFLPENSQN----- 445

4p1ps           -----------GLILPERSQITIHVFDVHR-NPKYWDS-PNEFRPERFLPENCQN----- 446

4P2ps           -----------GLILPERSQITIHIFDVHR-NPKYWDS-PNEFRPERFLPENCQN----- 447

4P3ps           -----------GLILPSGTQIHIHTFDIHR-NPKHWDS-PNEFRPERFLPENSQN----- 447

4p2m            -----------GLILPKRSQINIHVFDIHR-NPKYWES-PEEFRPERFLPQNCLK----- 448

4ac1m           -----------GMVMPKDTQISIHIYDIMR-DPRHFPK-PDLFQPDRFLPENTVN----- 438

4AC1ps          -----------GLILPKDTQISIHIYDIMR-DPRHFPN-PHEFQPERFLPENTVD----- 438

4ac2ps          -----------GLVMPKDTHINIHIYDIMR-DPRHFPN-PNAFQPERFLPENTVD----- 439

4ac2m           -----------GLIMPKNTQINIHLYEIMR-DARHFSN-PKMFQPDRFFPENTVN----- 439

4ac3m           -----------GLVLPKNAQISIHIYDIMR-DARHFPK-PNQFLPERFLPENSVN----- 438

311a1m          ------------RTYCAGVTLWINMYGLAH-DKEYYPD-PYAFKPERWLPEDGAV----- 413

311a1ps         ------------RTYCAGVTLWINMYGLAH-DASYFPD-PYVFKPERWMQETELQ----- 362

316a1m          ------------AELPCGSEIYINLYELQR-NEVRYPK-ANHFDAQRFLD---------- 412

316A1ps         ------------GTLPFGAEIYVNLFEMQR-NEDRYLN-ASHFRAERFLE---------- 417

313a2m          ------------VVIPKGMTISIDIFNTQR-NTDYWGSEAAQFNPENFLPEKIH------ 421

313a3m          ------------VVIPKGVGIGIDIFATHR-NRDHWGTDPSSFNPDHFLPDNVR------ 421

313a1m          ------------VLIPKGVVIGIDMFHTHR-NPEVWGPDADNFNPDNFLAENME------ 421

313C1ps         ------------ILIPKGVTVAIDIFNTHR-NKDFWGLGADTFNPDNFLPEHIQ------ 422

313C2ps         ------------ILLPKSLTLCLDIFHTHR-NKDSWGPEADKFNPDNFLPENIS------ 422

313a5m          ------------FYIPEGVTLMIDIFHTHR-NKDIWGPQANAFNPDNFLPENKR------ 416

313a4m          ------------IVVPKGVQIAIDIYHMHR-SKKIWGPDAETFNPDHFLPHNIQ------ 423

313a4ps         ------------IVVPKGVQIAINMFHMHR-SKKIWGPEAESFNPDNFLPHNTR------ 420

313A4bps        ------------TVIPKGVQIMIDIFHMHR-SKKIWGPEAETFNPDNFLAHHTGG----- 419

313b1m          ----------GEFLIPRGTQIGIDIYNMQR-DERVWGPLSRTYNPDAHFGLDSP------ 432

313b1ps         ----------GDFLIPRGTQIGIDIYNMQR-DERVWGPLARTYNPDAHFGPEAP------ 431

318a1m          ----------HETIVPQNSIVVLDTFNMQR-DERWWGANARQFDPQRFLDQEEEQLSKGH 447

318A1ps         ----------REAVVPQNSIIVLDTFNMQR-EEEWWGDNAKQFDPQRFLDQDDQPDQSPE 451

18a1m           ------------YTIPAGSHVIPLINSVHM-DPNLWEK-PEEFRPSRFIDTEG------- 448

18a1ps          ------------YTIPAGSHVIPLINSVHM-DPNLWEK-PEEFRPSRFIDTEG------- 449

306A1m          ------------YFIKGGSMIVCSEWAIHM-DPVAFPE-PEEFRPERFLTADG------- 487

306A1ps         ------------YRIAAGSMIVSLQWAIHM-DPAVWPE-PEQFRPDRFLNAEG------- 505

303a1m          ------------YEIPKDTMVIACFRGMLI-NPVDFPD-PESFNPDRYLFDG-------- 430

303A1ps         ------------YEIPKDTMVIACFRGMLI-NPVDFPE-PETFNPERYLFDG-------- 430

305a1m          ------------YDIPKNATILISLRSVHL-DKEHWKD-PLEFRPERFIDSAG------- 432

305A1ps         ------------YDIPKNATILINLRSVHL-DEKHWVD-PLQFRPERFIDVGG------- 434

304a1m          ------------YRIPKDTIVVPSLYAFHS-DARIWSD-PEQFRPERFLDADGK------ 436

304a1ps         ------------YHIPKDTIVVPSLYAYHS-DARVWSD-PEQFRPERFLDDQGE------ 436

307a1m          ------------YGVTKGTIVFINNYVLNT-SEKFWVN-PKEFNPLRFLEPSKE------ 443

307a1ps         ------------HGVTAGTIVFINNYVLNR-SREHWED-SHQFEPQRFLEPST------- 440

307a2pm         ------------------------------------------------------------

307a2pps        ------------FGVTRGTIIFINNYMLNM-SEKYWNS-PDHFEPERFLDENYRR----- 447

 

                               13A

12a4m           -----------------ANELKSTNPFVFLPFG-FGPR 480

12a5m           -----------------ANDLKTKNPFVFLPFG-FGPR 480

12A4ps          -----------------ANDLKLKNPFVFLPFG-FGPR 479

12A5ps          -----------------ANDLKLKNPFVFLPFG-FGPR 479

12c1m           -------------------MNKDLNAFIYLPFG-FGPR 468

12c1ps          -------------------LRNNLNPFVYLPFG-FGPR 477

12e1m           ---------------------ETATPFMYLPFG-FGPR 459

12e1ps          ---------------------DTATPFMYLPFG-FGPR 462

12d1m           ---------------------MQVSPFTFLPFG-FGPR 465

12d1ps          ---------------------MQVSPFTFLPFG-FGPR 465

12b2m           ------------------PAARTRNPFVYLPFG-FGPR 477

12B2ps          ------------------PEARTRNPFVYLPFG-FGPR 480

49A1m           ------------------HANQKIHPFVSLPFG-FGRR 534

49A1ps          ------------------HASHKIHPFVSLPFG-FGRR 540

301a1m          ---------------------GKLHPFASLPYG-YGAR 500

301A1ps         ---------------------GKLHPFASLPYG-YGAR 505

302a1m          ----------------------ALNPYLVLPFG-HGMR 432

302A1ps         ----------------------ALNPYLVLPFG-HGMR 430

314a1m          ----------------------VDNASIVVPFG-VGRR 486

314a1ps         ----------------------VDSASIVVPFG-VGRR 487

315a1m          ----------------------VHKSHGSLPFA-IGQR 464

315a1ps         ------------------------S-HGSLPFA-IGQR 460

6a2m            ------------------------ESVEWLPFG-DGPR 449

6a2ps           ------------------------DSVEWLPFG-DGPR 449

6a8m            ------------------------PSVAWLPFG-DGPR 449

6a18m           ------------------------PSVAWLPFG-EGPR 449

6a8ps           ------------------------NSLAWLPFG-DGPR 448

6a9m            ------------------------DSVEWLPFG-DGPR 447

6a21m           ------------------------DSVEWLPFG-DGPR 447

6a21ps          ------------------------DSVEWLPFG-DGPR 449

6a17m           ------------------------PSCTWLPFG-EGPR 442

6a23m           ------------------------PSCTWLPFG-EGPR 443

6A17ps          ------------------------PACAWLPFG-EGPR 441

6A23ps          ------------------------PACTWLPFG-EGPR 440

6a20ps          ------------------------PPCTFLPFG-DGPR 441

6a20m           ------------------------PACTFLPFG-DGPR 453

6a19m           ------------------------PTCAFLPFG-AGPR 443

6a22m           ------------------------PTAAWLPFG-DGPR 437

6A22ps          ------------------------PTAAWLPFG-DGPR 437

6a13m           ------------------------HPFAYLPFG-EGPR 433

6A13ps          ------------------------HPMAYLPFG-EGPR 433

6a14m           ------------------------HPMAYLPFG-DGPR 462

6A14ps          ------------------------HPMAYLPFG-DGPR 443

6a15pm          ------------------------HPFAYLPFGTFGPR 223

6a16m           ------------------------HPTAFLGFG-DGPR 461

6A16ps          ------------------------HSMAFLGFG-DGPR 438

6u1m            ------------------------PAAAFLPFG-DGLR 425

6u1ps           ------------------------PAMSFLPFG-DGLR 427

317a1m          ------------------------EQGTWFGFG-VGAR 459

317a1ps         ------------------------EQGTWFGFG-VGAR 459

6g1m            ------------------------VAMAYQPFG-SGPH 456

6G1ps           ------------------------EAMAYQPFG-SGPH 458

6w1m            ------------------------NMDAYMPFG-VGPR 448

6w1ps           ------------------------NMDAYMPFG-VGPR 450

6v1m            ------------------------APMSYMPFG-AGPR 463

6v1ps           ------------------------APMSYLPFG-AGPK 464

6g2m            ------------------------TPYTYMPFG-LGPH 458

6g2ps           ------------------------TPYTYMPFG-LGPH 458

6t1m            ------------------------HPMTYLPFG-AGPR 470

6t2pm           -------------------------------FG-AGPR 352

6t1ps           ------------------------HPMTYLPFG-AGPR 474

6t3m            ------------------------HPMTYIPFG-AGPH 442

6t3ps           ------------------------IPMTYIPFG-AGPH 443

9b1m            ------------------------IPYTYLPFG-VGPR 447

9b2m            ------------------------VPYTYLPFG-VGPR 447

9B2ps           ------------------------VPYTYLPFG-VGPR 447

9f2m            ------------------------QPFTYFPFG-LGQR 458

9f3pm           -------------------------------K------ 385

9F2ps           ------------------------QPFTYYPFG-LGQR 459

9c1m            ------------------------RQFTYLPFG-VGQR 462

9c1ps           ------------------------KPFTYLPFG-IGQR 465

9h1m            ------------------------R--VYMPFG-VGPR 460

9h1ps           ------------------------RPGTFLPFG-LGPR 462

6d2m            -------------------------QAAYMPFG-EGPR 455

6d2ps           -------------------------QAAYMPFG-EGPR 459

6d4m            -------------------------PTAFMPFG-EGPR 455

6d4ps           -------------------------PTAFMPFG-EGPR 455

6d5m            -------------------------QAAYLPFG-EGPR 451

6D5ps           -------------------------PTAYMPFG-EGPH 451

310a1m          --------------------EDKTKSNVFIGFG-IGGS 426

310a1ps         ----------------------DCKSNAFIGFG-IGGA 422

28a5m           --------------------KTFRERGVFMGFG-DGPR 448

28A5ps          --------------------KKFRERGTFMGFG-DGPR 448

28d1m           --------------------KKYRDQGLFFGFG-DGPR 444

28d1ps          --------------------RKYREAGVYYGFG-DGPR 443

28d2m           --------------------KSYRDRGVYLAFG-DGPR 444

28c1m           --------------------KNCKQQGIFLGFG-NGPR 442

28c1ps          --------------------KRFKQMGVFLGFG-NGPR 442

309a1m          ---------------------VLTKRGCFLPFG-DGPR 450

309a1ps         ---------------------VLTKRGCYLPFG-DGPR 450

309a2m          ---------------------ELMRKGIFLPFS-DGPR 450

309a2ps         ---------------------ELIRKGVFLPFS-DGPR 453

308a1m          -----------------------PMGCRFLGFG-AGPR 429

308a1ps         -----------------------PMGCRFLGFG-AGPR 442

4aa1m           ----------------------R-HPYAFLPFS-AGPR 452

4aa1ps          ----------------------R-HPYAFIPFS-AGPR 464

4C3m            ----------------------RH-PFAYIPFS-AGPR 479

4C3ps           ----------------------RH-PFAYIPFS-AGPR 478

4d1m            ----------------------KLNPYAYIPFS-AGPR 454

4D1ps           ----------------------KLNPYAYIPFS-AGPR 457

4d1malt         ----------------------KLNPYAYIPFS-AGPR 445

4D1psalt        ----------------------KLNPYAYIPFS-AGPR 458

4s3m            ----------------------QMHPFAFAAFS-AGPR 434

4s3ps           ----------------------QMHPFAFAAFS-AGPR 435

312a1m          ----------------------KIEATTFIPFM-AGAR 453

312a1ps         ----------------------KIEATTFIPFM-TGAR 454

4g1m            ----------------------NRHYYSFIPFS-AGPR 495

4G1ps           ----------------------NRHYYSFIPFS-AGPR 491

4g15m           ----------------------NRHYYAFVPFS-AGPR 517

4G15ps          ----------------------NRHYYAFVPFS-AGPR 517

4d2m            ----------------------QIHPYAYIPFS-AGPR 447

4D2ps           ----------------------QTHPYAYIPFS-AGPR 451

4d14m           ----------------------EISPFAYTPFS-AGPR 452

4d14ps          ----------------------EINPFAYTPFS-AGPR 454

4d8m            -----------------------VAPFKMIPFS-AGPR 449

4d8ps           -----------------------FSPFTFIPFS-AGPR 450

4ae1m           ----------------------RLSPYSYIPFS-AGPR 441

4AE1ps          ----------------------KKGAYSNIPFS-AGPR 447

4d20m           ----------------------GHNTFAYVPFS-AGPK 453

4D20ps          ----------------------DRETFAYLPFS-AGPK 455

4d21m           ----------------------NTPPLAYIPFS-SGPK 454

4e2m            --------------------------FEYVPFS-AGPR 442

4e2ps           --------------------------FEYVPFS-AGPR 442

4e1m            --------------------------FEYVPFS-AGPR 442

4e1ps           --------------------------FEYVPFS-AGPR 443

4e3m            --------------------------FEYLPFS-AGPR 441

4e3ps           --------------------------FEYVPFS-AGPR 441

4ad1m           ----------------------GIEAFKSVPFS-AGPR 443

4AD1ps          ----------------------GIEAFKSVPFS-AGPR 444

4p1m            ----------------------R-HTYAYVPFS-AGQR 457

4p3m            ----------------------R-HTYAYIPFS-AGQR 459

4p1ps           ----------------------R-HTYAYIPFS-AGQR 460

4P2ps           ----------------------R-HTYAYIPFS-AGQR 461

4P3ps           ----------------------R-SVYAYIPFS-AGQR 461

4p2m            ----------------------R-HPYAYIPFS-AGQR 462

4ac1m           ----------------------R-HPFAYVPFS-AGQR 452

4AC1ps          ----------------------R-HPFAFVP------- 446

4ac2ps          ----------------------R-HPFAFVPFS-AGQR 453

4ac2m           ----------------------R-HPFAFVPFS-AGQR 453

4ac3m           ----------------------R-HPFAFVPFS-AGPR 452

311a1m          ----------------------APPAFSYIPFS-GGPH 428

311a1ps         ----------------------AEVPFSYIPFS-GGPH 377

316a1m          ------------------------SPPELLSYS-LGPR 425

316A1ps         ------------------------SPPEIYSFS-MGPR 430

313a2m          ----------------------DRHPYAFIPFS-KGKR 436

313a3m          ----------------------DRHPYAYIPFS-KGRR 436

313a1m          ----------------------QKHPYAYIPFA-RGKR 436

313C1ps         ----------------------ERHPYVFIPFN-RGKR 437

313C2ps         ----------------------KIHQYAYIPFN-KGKR 437

313a5m          ----------------------ARPPYSYLPFS-KGKK 431

313a4m          ----------------------DKHPYAYIPFT-KGIR 438

313a4ps         ----------------------DKHPYA---------- 426

313A4bps        ----------------------EKHPYAFIPFT-KGIR 434

313b1m          ----------------------QRHAFAFVPFT-KGLR 447

313b1ps         ----------------------SRHAFAFVPFT-KGLR 446

318a1m          ---------NDSGSGEKRRQRDRRHSYSFLPFS-NGLR 475

318A1ps         GEDISGSSIPKTNGQQKQQKQQRRHSYSFLPFS-KGLR 488

18a1m           ---------------------KVRKPEYFIPFG-VGRR 464

18a1ps          ---------------------KVRKPEYFIPFG-VGRR 465

306A1m          ---------------------AYQAPPQFIPFS-SGYR 503

306A1ps         ---------------------HYSAPPQFIPFQ-TGKR 521

303a1m          ---------------------HLKLPEAFNPFG-FGRH 446

303A1ps         ---------------------QLKLPEAFNPFG-FGRH 446

305a1m          ---------------------KCFKDEYFMPFG-MGRR 448

305A1ps         ---------------------KCFKDEFFMPFG-IGRR 450

304a1m          ---------------------LCLKLDVSLPFG-AGKR 452

304a1ps         ---------------------LCLKLDVSFPFG-AGKR 452

307a1m          QSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFS-IGKR 465

307a1ps         EGRRDSRGSDSGIESDQKEFQLRKNIPHFLPFS-IGKR 477

307a2pm         --------------------------------------

307a2pps        --RRGSEGSDSGIEFEKDTHQLKKNIPHFLPFS-IGKR 506

 

                   14A           14B

12a4m           MCVGKRIVEMELELGTARLIRNFNVEFNYP-----T------------------------ 511

12a5m           MCVGKRIVEMELELGTARLIRNFNVEFNHS-----T------------------------ 511

12A4ps          MCVGKRIVDMELELGIARLIRNFSIEFNHP-----T------------------------ 510

12A5ps          MCVGKRIVDMELELGIARLIRNFNIEFNHP-----T------------------------ 510

12c1m           MCVGKRIVDLEMELTVANLVRNFHIEYNYS-----T------------------------ 499

12c1ps          MCVGKRIVDLEMELTVANLVRNFHIEFNYP-----I------------------------ 508

12e1m           SCAGKRIVDMMLEIAISRLVRNFKIGFDYP-----I------------------------ 490

12e1ps          ACAGKRIVDMMLEIGVARLVRNFEIGFDYP-----I------------------------ 493

12d1m           MCIGKRVVDLEMETTVAKLIRNFHVEFNRD-----A------------------------ 496

12d1ps          MCLGKRVVDLEVETSVAKLIRNFHVEFLHD-----A------------------------ 496

12b2m           TCIGKRIAELEIETLLVRLLRSYKVSWLPE-----T------------------------ 508

12B2ps          TCIGKRIAELEIETLLVRLLRRYHVNWLPN-----A------------------------ 511

49A1m           MCVGRRFAEIELHTLLAKIFRKYKVSYNS------G------------------------ 564

49A1ps          MCVGRRFAEIELHTLLAKIFRKYKVSYSS------G------------------------ 570

301a1m          MCLGRRFADLEMQILLAKLLRNYKLEYNH------K------------------------ 530

301A1ps         MCLGRRFADLEMQILLAKLLRNYKLEYNH------K------------------------ 535

302a1m          ACIARRLAEQNMHILLLRLLREYELIWSG-S---DD------------------------ 464

302A1ps         ACIARRLAEQNIHVLLLRLLRNFELIWRGGT---DA------------------------ 463

314a1m          SCPGKRFVEMEVVLLLAKMVLAFDVSFVK------------------------------- 515

314a1ps         TCPGKRFVEMEVVLLLAKLVVAFDVSFVK------------------------------- 516

315a1m          SCIGRRVALKQLHSLLGRCAAQFEMSCLNE-----M------------------------ 495

315a1ps         SCIGRRVALKQLHSLLGKCTTQFEMQCLNE-----Q------------------------ 491

6a2m            NCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPLK------------------------ 485

6a2ps           NCIGMRFGQMQARIGMAQLLSRFKLSLCDKTEIPLK------------------------ 485

6a8m            NCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLV------------------------ 485

6a18m           NCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLT------------------------ 485

6a8ps           NCIGLRFGKMQTTIGLALLIKNFKFSTCPKTPDTLS------------------------ 484

6a9m            NCIGMRFGQMQARSGLALLINRFKFSVCEQTTIPIV------------------------ 483

6a21m           NCIGMRFGQMQARIGLALLIKDFKFSVCEKTTIPMT------------------------ 483

6a21ps          NCIGMRFGQMQARIGMAMLLKDFKFSVCDETAFPMK------------------------ 485

6a17m           NCIGLRFGMMQTCVGLAYLIRGYKFSVSP-ETQIPM------------------------ 477

6a23m           NCIGLRFGLMQACVGLAYLIRGYKFSVST-ETQIPM------------------------ 478

6A17ps          NCIGLRFGLMQTCVGLAYLIKGYRFSVAP-ETQIPI------------------------ 476

6A23ps          NCIGLRFGIMQTCVGLAYLIKGYRFSVAP-ETQIPM------------------------ 475

6a20ps          TCIGLRFGRMQIVVGLALLIHNFKFEVHPTKTTVPL------------------------ 477

6a20m           NCIGLRFGRMQVIVGMALLIHNFKFEFHPTKTVVPL------------------------ 489

6a19m           NCIGLRFGRMQVIIGLALLIHNFRFELHP-KTPVPM------------------------ 478

6a22m           NCIGMRFGKMQTTIGLVSLLRNFHFSVCP-RTDPKI------------------------ 472

6A22ps          NCIGMRFGKMQTSIALVNLLRRFHFSVCP-RTESKI------------------------ 472

6a13m           NCIGERFGKLQVKVGLVYLLRDFKFSRSE-KTQIPL------------------------ 468

6A13ps          NCIGERFGKMQVKIGIAYILRDFQFRQSE-RTQIPL------------------------ 468

6a14m           NCIGLRFGKIQAKIGLVSLLRRFKFSVSN-RTDVPL------------------------ 497

6A14ps          NCIGLRFGKIQAKIGLVSLLRRFKFGISK-RTEIPL------------------------ 478

6a15pm          SCIGLRFGKMQAKIGIVSLCQRFKFGDSD-LTDIPL------------------------ 258

6a16m           NCIGLRFGRMQVKVGLITLLRRFRFSLPP-GSPTQL------------------------ 496

6A16ps          HCIGQQFGRMQIKIGLIALLTKYQFSSVP-GFPDEL------------------------ 473

6u1m            GCIAARFAEQQLLVGLVALLRQHRYAPSA-ETSIPV------------------------ 460

6u1ps           GCIAAQFVEQELLVGLVTLLQYHRYTPCS-KTAIPL------------------------ 462

317a1m          SCIGIQFAQLQLRLALALLLSEYEFSLNT-RKPLIN------------------------ 494

317a1ps         SCIGIQFAQLQLRLALALLLMEYEFTLNS-RKPLVS------------------------ 494

6g1m            NCIGSRIGLLQSKLGLVSLLKNHSVRNCE-ATMKDM------------------------ 491

6G1ps           NCIGSRIGLLQTKLGLVHILKNHSVKMCA-DTIKEM------------------------ 493

6w1m            NCIGMRLGLLQSKLGLVHILRNHRFHTCD-KTIKKI------------------------ 483

6w1ps           NCIGMRLGLLQSKLGLVHLLRNHRVLWCD-KTVKTI------------------------ 485

6v1m            NCIGMQIGLLQIKLGLVYFLHQHRVEICD-RTVERI------------------------ 498

6v1ps           HCIGMQIGQLQIKLGLIYFLRRHRVELCE-KTVERI------------------------ 499

6g2m            GCIGERFGYLQAKVGLVNLLRNHMITTSE-RTPHRM------------------------ 493

6g2ps           GCIGERFGLLQAKVGLVNLMRNHQVTTSE-RTPRRM------------------------ 493

6t1m            GCIGTLLGQLEIKVGLLHILNHFRVEVCE-RTLPEM------------------------ 505

6t2pm           GCIGTLLGQLGIKVGLLHTLKHFRVELCE-RTLPEM------------------------ 387

6t1ps           GCIGTLLGQLEIKVGLLHILKNFRVELCE-RTLPEM------------------------ 509

6t3m            GCIGSRLGVLQLKLGIVHILKQYWVETCE-RTVSEI------------------------ 477

6t3ps           GCIGSRLGSLQLKLGLAHILRLCRVEVCE-QTVPQI------------------------ 478

9b1m            SCIGNRYAVMQAKGMLYNLMLNYKIEASP-RTTRDM------------------------ 482

9b2m            NCIGNRYALMQVKGMLFNLLLHYKIEASP-RTIKDL------------------------ 482

9B2ps           NCIGNRYALMQVKGMLYNLLIRYKIERSP-KTVKDL------------------------ 482

9f2m            NCIGSRFALLEAKAVIYYLLKDYRFAPAK-KSCIPL------------------------ 493

9f3pm           ----------EAKAVIYYLLKDYRFAPAK-KSCIPL------------------------ 410

9F2ps           NCIGSRFALLEAKAVIYYLLKDYRFAPAK-KSCIPM------------------------ 494

9c1m            SCIGNRLALMEVKSLIFQLVLRYHLKPTD-RTPADM------------------------ 497

9c1ps           SCIGNRMALMEVKALLYGLVRRFRLEPAE-RTTTDM------------------------ 500

9h1m            NCIGNRMALMELKSIVYQLLLNFKLLPAK-RTSRDL------------------------ 495

9h1ps           NCIGSRLALMELKSIVYQLILGFRLVPAQ-KTSTNL------------------------ 497

6d2m            HCIALRMGKVNSKVAVAKILANFDLVQSPR--KEVE------------------------ 489

6d2ps           HCIALRMGEVNTKVAVAKILANFDLVQAPH--KEVG------------------------ 493

6d4m            ICIAQRMGRINSKLAIIKILQNFNVEVMS---RSEI------------------------ 488

6d4ps           ICIAQRMGLLNAKLAIINVLKNFNVEVMS---KRQL------------------------ 488

6d5m            MCIGARMGKVNVKIAIAKVLSNFDLEIRKE--KCEI------------------------ 485

6D5ps           NCIGLRMGKVNVKIAVAKILSNFSLEMSKE--KREI------------------------ 485

310a1m          QCVGQNFAKLVIKVALIKLLQNFHLELDANQVKTLK------------------------ 462

310a1ps         QCVGQNFAKMVIKVALIKLLQNFHLELDATLAETIE------------------------ 458

28a5m           VCIGMRFATVQIKAAIVELISKFNVKIND-KTRKDN------------------------ 483

28A5ps          VCIGMRFALAQIKAAAVELITKYNVKVNP-KTRKDN------------------------ 483

28d1m           ICPGMRFSLTQIKAALVEIVRNFDIKVNP-KTRKDN------------------------ 479

28d1ps          VCPGMRFALTQVKAALVEIVQNFEIKVNP-KTRSDN------------------------ 478

28d2m           HCPGMRFALTQLKAALVEILRNFEIKVNP-KTRSDN------------------------ 479

28c1m           QCVGMRLGLAMAKAALAAIVQRFEVVVSP-RTLNGT------------------------ 477

28c1ps          QCVGMRLGLAQAKAALAAIVQRFEVRVHP-RTADGL------------------------ 477

309a1m          ICLGMRVGQLSVKTAIVHILSNYQVEQMK-KVPLG------------------------- 484

309a1ps         ICLGMRVGQLSVKTAILHILSQYQVEQTT-KVPMD------------------------- 484

309a2m          ICMGVPLAMLTLKSALVHILSNFQVVRGR-DRLIPK------------------------ 485

309a2ps         ICMGMRLALLTLKSALIHILSDFQVVRGK-KRLVPN------------------------ 488

308a1m          MCPGMRLGLLQTKAALTTLLQDHCVQLAD-EDQCRV------------------------ 464

308a1ps         MCPGMRLGLAQTKAALVTLLRDYSFSLAD-QAQDPV------------------------ 477

4aa1m           YCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTT--------------------------- 485

4aa1ps          YCIGNRFAIMEMKTIVSRLLRSFQLLPVAGKTT--------------------------- 497

4C3m            NCIGQKFAILEEKAVISTVLRKYKIEAVDRR-ED-------------------------- 512

4C3ps           NCIGQKFAILEEKAVISTVLRKYKIEAVDRR-ED-------------------------- 511

4d1m            NCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEP-------------------------- 488

4D1ps           NCIGQKFAMLEIKAIVANVLRHYHIDFVGDTTEP-------------------------- 491

4d1malt         NCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEP-------------------------- 479

4D1psalt        NCIGQKFAMLEIKAIVANVLRHYHIDFVGDTTEP-------------------------- 492

4s3m            NCIGQKFAMLELKTSLAMLLRSYRFLPDKDH--Q-------------------------- 466

4s3ps           NCIGQKFAMLELKCSLSSLLRSFQFMPDEDH--Q-------------------------- 467

312a1m          SCMGQRYAMVMLKMVLAHLLRNFLFEPLGERQVK-------------------------- 487

312a1ps         SCLGQRYAMVMIKSVMAHLLRSYRFEPIGERQVK-------------------------- 488

4g1m            SCVGRKYAMLKLKVLLSTIVRNYIVHSTDTE-AD-------------------------- 528

4G1ps           SCVGRKYAMLKLKVLLSTIVRNYIVHSTDTE-AD-------------------------- 524

4g15m           SCVGRKYAMLKLKILLSTILRNYRVYSDLTE-SD-------------------------- 550

4G15ps          SCVGRKYAMLKLKILLSTILRNYRVYSDLSE-SD-------------------------- 550

4d2m            NCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRH-------------------------- 481

4D2ps           NCIGQKFALLEMKSTISKLLRNFELLPLGPEPRP-------------------------- 485

4d14m           NCIGQKFAMLEMKSTISKMVRHFELLPLGEEVQP-------------------------- 486

4d14ps          NCIGQKFAMLEMKSTISKMVRHFELLPLGEDVQL-------------------------- 488

4d8m            NCIGQKFAQLEMKMMLAKIVREYELLPMGQRVEC-------------------------- 483

4d8ps           NCIGQKFAQLEMKMMLAKIVREYELLPLGEPVEC-------------------------- 484

4ae1m           NCIGQKFALLEMKTMVTKVIRHYQLLPMGADVEP-------------------------- 475

4AE1ps          NCIGQKFAMFEVKTMIIKMLRNFILLPIGPDVEP-------------------------- 481

4d20m           NCIGQKFAVLEMKVLISKVLRFYELLPLGEELKP-------------------------- 487

4D20ps          NCIGQKFAMLEMKALVSKVLRCYELLPRGPEVKP-------------------------- 489

4d21m           NCIGQKFANLQMKALISKVIRHYELLPLGADLKA-------------------------- 488

4e2m            NCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKY 502

4e2ps           NCIGQKFALLEIKTVVSKIIRHFEVLPALDELASKDGYISTSLGYPPEERKKRDLLRHKY 502

4e1m            NCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTLGLQPAEKKSRDAHNHKY 502

4e1ps           NCIGQKFALLEIKTVVSKIIRHFEVLPALDELASKDGYIRTTLGLPPTEKRKRDLQQHKY 503

4e3m            NCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKREAGRHKY 501

4e3ps           NCIGQKFALLELKTVISKLVRSFEVLPAVDELLSTDGQLNTYLGLSPAEKQKREAGRHKY 501

4ad1m           RCIAEKFAMYQMKALLSQLLRRFEILPAVDGLPPGINDHSREDCVPQSE----------Y 493

4AD1ps          RCIAERFAMYQLKALLSQLLRNFEILPPVNGLSSGINDHSQVECVPQSE----------Y 494

4p1m            NCIGKKYAMQEMKTLMVVLLKQFKVLKAIDP-Q--------------------------- 489

4p3m            NCIGQKFAMQEMKTLMVALLKQFQILPEIDP-K--------------------------- 491

4p1ps           NCIGQKFAMQEMKTLIVVLLKKFRILPLIDP-K--------------------------- 492

4P2ps           NCIGQKFAMQEMKTLIVVLLKKFRILPLIDP-K--------------------------- 493

4P3ps           NCIAQKFAMQEMKTLMTVILKKFEIQPLVDP-N--------------------------- 493

4p2m            NCIGQKYAMQEMKTLMVVILKHFKILPVIDP-K--------------------------- 494

4ac1m           NCIGQKFAILEMKVLLAAVIRNFKLLPATQL-E--------------------------- 484

4AC1ps          ----------EIKVLLAAVLRNFRILPVTRL-E--------------------------- 468

4ac2ps          NCIGQKFAILEIKVLLAAVLRNFKILPDTRF-E--------------------------- 485

4ac2m           NCIGQKFAILEIKVLLAAVIRNFKILPVTLL-D--------------------------- 485

4ac3m           NCIGQKFGVLEIKVLLAAVIRNFKLLPATQL-E--------------------------- 484

311a1m          VCIGRRYSLLLMKLLTARLVREFQMELSPEQAP--------------------------- 461

311a1ps         VCIGRRYALLLMKLLTARIARAFQLELRLGQPE--------------------------- 410

316a1m          CCPARKFSMQLLKTLLAPILANFEVLPYGDEVR--------------------------- 458

316A1ps         CCPAKQFSMVLLKTLIAPILSNFELLPYGDAPR--------------------------- 463

313a2m          NCIGWRYGLMSSKLALVKILRNYKLKTSFPYEN--------------------------- 469

313a3m          NCIGWKYGLMSSKLALSKILRNCKVSTSFRYED--------------------------- 469

313a1m          NCIGSKYAMMSSKFALCRILRNYKISTSTLYKD--------------------------- 469

313C1ps         NCAGRKYAEISIKIALAKILRNFRLSTSFRFED--------------------------- 470

313C2ps         SCIGMKYAEIAAKVALSKILRNYKLSTSFRTED--------------------------- 470

313a5m          TCLGWKLSLISAKLALAKILRNYMLSTTFLYKD--------------------------- 464

313a4m          NCIGWRYALISAKVTLAKLLRNYRFKTSFPFEN--------------------------- 471

313a4ps         ------------------------------------------------------------

313A4bps        NCIGWRYASISVKVILAKLLRNFSYKTSFKFED--------------------------- 467

313b1m          MCIGYRYAQMLMKLLLARIFRSYRISTEARLEE--------------------------- 480

313b1ps         MCIGYRYAQMLMKLLLAKIFRSYRIITEARLDQ--------------------------- 479

318a1m          SCIGRRYGLFIMKVFLVKLITNFDFQSDFELEK--------------------------- 508

318A1ps         SCIGRRYGLFIMKVFLVKLIVAFDFSSDFQLDQ--------------------------- 521

18a1m           MCLGDVLARMELFLFFASFMHCFDIALPEGQ---------------------------PL 497

18a1ps          MCLGDVLAKMELFLFFASFMHCFDIALPEGQ---------------------------PL 498

306A1m          MCPGEEMARMILTLFTGRILRRFHLELPSG----------------------------TE 535

306A1ps         MCPGDELARMMLTLFAGRILRRFHVEMVPG----------------------------CD 553

303a1m          RCMGDLLGRQNLFMFTTTVLQNFKMVAIPG----------------------------QV 478

303A1ps         RCMGDLLGRQNLFMFTTTVLQHFKLVSIPG----------------------------QM 478

305a1m          RCLGDALARACIFSFLVRIVQHFSVVLPAG----------------------------ES 480

305A1ps         RCLGDALARACIFSFLVRIVQHFCIVLPPG----------------------------ET 482

304a1m          LCAGETFARNMLFLVTATMCQHFDFVLGPN----------------------------DR 484

304a1ps         LCAGETFARNMLFLMTAAMCQNFNYVLAPG----------------------------DQ 484

307a1m          TCIGQNLVRGFGFLVVVNVMQRYNISSHNP-----------------------------S 496

307a1ps         TCIGQNLVRGFGFLLLANLLQGYNVSSGDP-----------------------------T 508

307a2pm         ------------------------------------------------------------

307a2pps        TCIGQNLVRGFGFVLLANIVQSYNITSADI-----------------------------S 537

 

12a4m           ENAFRSALINLPNIPLKFKFIDLPN---------------- 536

12a5m           KNAFRSALINLPNIPLKFKFTDVPN---------------- 536

12A4ps          EKAFRSSLISLPNIPLKFKFTDLPN---------------- 535

12A5ps          ENAFRSAMISLPNIPLKFKFTDLPN---------------- 535

12c1m           EKPYKCRFLYKPNIPLKFKFTDLKY---------------- 524

12c1ps          ENAFKRSFLNMPNIPLRFKFTDVNYS--------------- 534

12e1m           ENAFKAQFFVQPNIPFKFKFIERNE---------------- 515

12e1ps          ENAFKTQFFVQPNIPFKFKFVERTA---------------- 518

12d1m           SRPFKTMFVMEPAITFPFKFTDIEQ---------------- 521

12d1ps          SRPYKTLFVMEPAIDFRFRFTDIQE---------------- 521

12b2m           PIEYESTIILSPCGDIRFKLEPVGDLM-------------- 535

12B2ps          PLQYKSTIILSPCGDIRFKFLPVEGVRESL----------- 541

49A1m           EFVYRVNSTYIPQSPLNFKLTLRDE---------------- 589

49A1ps          EFVYRVNSTYIPQSPLNFKLTLRED---------------- 595

301a1m          PLDYAVTFMYAPDGPLRFKMTRV------------------ 553

301A1ps         PLDYAVTFMYAPDGPLRFKMTRI------------------ 558

302a1m          EMGVKTLLINKPDAPVLIDLRLRRE---------------- 489

302A1ps         DLDVVTLLINKPDAPVMIELRSRSK---------------- 488

314a1m          PLETEFEFLLAPKTPLSLRLSDRVF---------------- 540

314a1ps         PLETEFEFLLAPKTPLSLKLRDRAI---------------- 541

315a1m          PVDSVLRMVTVPDRTLRLALRPRTE---------------- 520

315a1ps         PVDCMLRMVTVPDQTLRLALRPRSSE--------------- 517

6a2m            -YSPMSIVLG-TVGGIYLRVERI------------------ 506

6a2ps           -YEPKSFVLG-SIGGIYLRLERI------------------ 506

6a8m            -YDPKSFVLG-VKDGIYLKVETV------------------ 506

6a18m           -FDPHSAILLGIKGGIQLKVEAI------------------ 507

6a8ps           -YSPKSFVLA--VDGIHLKVEAV------------------ 504

6a9m            -YSKKTFLISS-ETGIFLKVERV------------------ 504

6a21m           -YNKEMFLIAS-NSGIYLKAERV------------------ 504

6a21ps          -YDLESFLIAS-KTGISLRVERV------------------ 506

6a17m           -KIVVKNILISAENGIHLKVEKLAK---------------- 501

6a23m           -KFVVKSILLSAENGIHLKVEKLSK---------------- 502

6A17ps          -KFVLKSFLLSAENGIYLKVETVSK---------------- 500

6A23ps          -KLILKSILLSAENGIYLKVKKVSK---------------- 499

6a20ps          -KFKVTDVLLCSEGGVHLNVSKVPR---------------- 501

6a20m           -EYRTDDFLLSSKGGIHLKVTRV------------------ 511

6a19m           -KYTINNLLLGSEGGIHLNITKVVRD--------------- 503

6a22m           -EFLKSNILLCPANGIYLKVQQLSQMSS------------- 499

6A22ps          -EFVKSNLLLCPANGIYLKVQEISKLK-------------- 498

6a13m           -KFSSRNFLISTQEGVHLRMEGLERP--------------- 493

6A13ps          -KFSSRTFLIGTQEGIHLIMEKLAAP--------------- 493

6a14m           -IFSKKSFLLTTNDGIYLKVERV------------------ 519

6A14ps          -ILDTRSFPLTTKNGIHLRVERI------------------ 500

6a15pm          -----------------------------------------

6a16m           -KVTKRNLILLPSDGVRLQVDPVESRLM------------- 523

6A16ps          -PISKGNVILRPRQGVLLKVHRVPE---------------- 497

6u1m            -EYDNRRLLLMPKSDIKLSVERVDKL--------------- 485

6u1ps           -EYDNGRLLLMPKTDIHLNVERVDN---------------- 486

317a1m          -LEDGIALTLMPLGVIEPGNEERAV---------------- 518

317a1ps         -LDDGIALQLTPLGVIEPGTEERAV---------------- 518

6g1m            -KFDPKGFVLQADGGIHLEIVNDRLYDQSAPSLQ------- 524

6G1ps           -KFDPKGFVLQSLTGIYLEIVNDRLYEESAARVH------- 526

6w1m            -EWAPTSPVMASKRDIILRVEKVSGKKDFGQK--------- 514

6w1ps           -EFAPFCGVLASKDEIYLRVERVSS---------------- 509

6v1m            -QFDAKFALLASEQRIYLKVDCL------------------ 520

6v1ps           -SFDAKFALLASEHRIYLKVADCL----------------- 522

6g2m            -QLDPKAIITQAKGGIHLRLVRDALGV-------------- 519

6g2ps           -KLDPKAIILQAQGGIHLRLVRDPLGI-------------- 519

6t1m            -RFDPKAFVLTAHNGTYLRFVKNSL---------------- 529

6t2pm           -RFDP-ASVLTAHNGTFLRFVRNSL---------------- 410

6t1ps           -VFDPKAFVLTAKGGTYLRFVKDTL---------------- 533

6t3m            -RFNPKSFMLESENEIYLRFCRSSL---------------- 501

6t3ps           -RFNPKTFMLESKDEIYLRFYRDKL---------------- 502

9b1m            -WESARGFNIIPTTGFWMQLVSRK----------------- 505

9b2m            -WGSASGFNFTPRSGFWMHLVPRK----------------- 505

9B2ps           -WEEARGFNLAPKAGYWMRLMPRK----------------- 505

9f2m            -ELITSGFQLSPKGGFWIKLVQRN----------------- 516

9f3pm           -ELISSGFQLSPKGGFWIKLVQRN----------------- 433

9F2ps           -ELASNGFQLTPKSGFWVKFVPRN----------------- 517

9c1m            -MSSISGFRLLPRELFWCKLESRGPA--------------- 522

9c1ps           -MGNIAGFRMMPRELFWCKFVARVDGEAKVQE--------- 531

9h1m            -LNDIRGHGLKPKNGFWLKFEARQ----------------- 518

9h1ps           -LDNIMGHNLQPKDGFWLKFESRK----------------- 520

6d2m            -FRFDAAPVLVTKEPLKLRLTKRK----------------- 512

6d2ps           -SASMLLPSWCPKRV-------------------------- 507

6d4m            -EFENSGIALIPKHGVRVRLSKRVPKLS------------- 515

6d4ps           -EFENSGIALLPKNGVKVRLSKRLPK--------------- 513

6d5m            -EFGVYGIPLMPKSGVPVRLSLKK----------------- 508

6D5ps           -EFSVHGIPLMPKGGVPVRISRKK----------------- 508

310a1m          -VSHRPAPFIHTKDGLKVKLKRREINTKFYS---------- 492

310a1ps         -ISHQPAPFIRTKDGLKVRLKRREIKPKFYN---------- 488

28a5m           -DYEPGQIITGLRGGIWLDLEKL------------------ 505

28A5ps          -LYDPMSFITSLQGGIWLDLEAL------------------ 505

28d1m           -EIDDTYFMPALKGGVWLDFVERN----------------- 502

28d1ps          -ELDDTFFMATLKGGIWLDFEARK----------------- 501

28d2m           -QIDDTFFMATLKGGIYLDFKDL------------------ 501

28c1m           -ELDPLIFVGVHKGGIWLQFVPRKNVTTK------------ 505

28c1ps          -ELDPYIFVGCHKGGIWLDFVSRPV---------------- 501

309a1m          ---ADSGMGIFLNGDVELKYTKLQK---------------- 506

309a1ps         ---ADTGLGIFLNGDVQLKYTKLQK---------------- 506

309a2m          ---GDSGFGVVLQGDVNLEYRRFFR---------------- 507

309a2ps         ---GDAGFGVVLQGNVHLEYRRFVR---------------- 510

308a1m          -EVSPLTFLTASRNGIWLSFKRRTRRY-------------- 490

308a1ps         -QVSPLTFLTASKHGIWLQLQKR------------------ 499

4aa1m           -IAATFRITLRASGGLWVRLKERDHPLIAH----------- 514

4aa1ps          -FDVSYRITLRASGGLWVRLKPRDHPISQTRDSDCFGL--- 534

4C3m            -LTLLGELILRPKDGLRVKITPRD----------------- 535

4C3ps           -LTLLGELILRPKDGLRVKITPRD----------------- 534

4d1m            -PVLIAELILRTKEPLMFKVRERVY---------------- 512

4D1ps           -PVLIAELILRTKDPLLFKLQDRVY---------------- 515

4d1malt         -PVLIAELILRTKEPLMFKVRERVY---------------- 503

4D1psalt        -PVLIAELILRTKDPLLFKLQDRVY---------------- 516

4s3m            -PKPLAELVTKSGNGIRLRILPRDENGTTA----------- 495

4s3ps           -PIPLAELVMKSGNGVRLRIQPRSQH--------------- 492

312a1m          -LKLNFVITLHTVEPYLCRAKNLD----------------- 510

312a1ps         -MKLNFVVTLHTVEPYYCRVRAVE----------------- 511

4g1m            -FKLQADIILKLENGFNVSLEKRQYATVA------------ 556

4G1ps           -FKLQADIILKLENGFNISLEKRKYATVA------------ 552

4g15m           -FKLQADIILKREEGFRVRLQPRTS---------------- 574

4G15ps          -FKLQADIILKREEGFRVRLQA------------------- 571

4d2m            ----SMNIVLRSANGVHLGLKPRA----------------- 501

4D2ps           ----AMNIVLRSANGVHLGLQPRSVLAS------------- 509

4d14m           ----VLNVILRSTTGINCGLKPRVY---------------- 507

4d14ps          ----VLNLILRSTTGINVGLKPRVY---------------- 509

4d8m            ----IVNIVLRSETGFQLGMRKRKHN--------------- 505

4d8ps           ----VINIVLRSDTGFQLGMRRRNDTQ-------------- 507

4ae1m           ----SIKIVLRSKSGVNVGLRPRLY---------------- 496

4AE1ps          ----SIKIVLRSRNGVHFGLRPRVY---------------- 502

4d20m           ----MLNFILRSASGINVGLRPRKALR-------------- 510

4D20ps          ----MMNFILRSSTGMNVGLRPRRSP--------------- 511

4d21m           ----TYTFILSSSTGNNVGLKPRTRVK-------------- 511

4e2m            DPILSAVLTLKSENGLYIRLKERH----------------- 526

4e2ps           DPLLSAVLTLKAENGLFIRLKERH----------------- 526

4e1m            DPILSASMTLKSENGLHLRMKQRLVCDST------------ 531

4e1ps           DPILLVAMSLKSENGIYLRLKERF----------------- 527

4e3m            DPILSAVLTLKSDNGLHLRLRERRS---------------- 526

4e3ps           DPILSAVLTLKSDNGLHLRLRERRH---------------- 526

4ad1m           DPVLNIRVTLKSENGIQIRLRKR------------------ 516

4AD1ps          DPVLNIRVTLKSENGIQIRLGKRAFVE-------------- 521

4p1m            KIVFHTGITLRTQDKIRVKLVRRT----------------- 513

4p3m            TIVFQTGLTLRTKNQIHVNS--------------------- 511

4p1ps           TIVFNVGITLRTQNNIQVKLVRRK----------------- 516

4P2ps           TIVFNVGITLRTQNNIQVKLVRRN----------------- 517

4P3ps           SIVFHVGITLRIKNHIRV----------------------- 511

4p2m            SIVFQVGITLRFKNKIKVKLVRRNCV--------------- 520

4ac1m           DLTFENGIVLRTQENIKVKLSKRVK---------------- 509

4AC1ps          DLTFENGIVMRTQQNVKVKLVRR------------------ 491

4ac2ps          DLTIENGIVLRTQQKVKVKLVQRVG---------------- 510

4ac2m           DLTFENGIVLRTKQNIKVKLVHRENK--------------- 511

4ac3m           DLTFENGIVLRTQQNIKVKFEARVK---------------- 509

311a1m          -LRLEAQMVLKAQQGINVSFLKQ------------------ 483

311a1ps         -LTLQAQMVLKTREGIHLAFTKR------------------ 432

316a1m          ---LDLRLVLGSSNGFQLALKPR------------------ 478

316A1ps         ---LDLRLSLGSSNGFQLALKPR------------------ 483

313a2m          -LEFVDHMVIKLAQSPQLAFERRTL---------------- 493

313a3m          -LEFVDNIGMELAQSPGLEFHRRT----------------- 492

313a1m          -LVYVDNMTMKLAEYPRLKLQRRG----------------- 492

313C1ps         -LSFVDNIVLEFKEQPLLELQHRR----------------- 493

313C2ps         -FVFIENLSIDFAKKPLLELQRRD----------------- 493

313a5m          -LRFIDNTTMKLAEQPLLAVKRRI----------------- 487

313a4m          -LYFVEDITMKLKSVPLLELQKRT----------------- 494

313a4ps         -----------------------------------------

313A4bps        -LVFIEDVTIKLKTVPKLQIQKRT----------------- 490

313b1m          -LLVKGNISLKLKDYPLCRVERR------------------ 502

313b1ps         -LLVKGNISLKLSNYPLCRVKRR------------------ 501

318a1m          -LQFVENISLKFKNADDILLTIQPKKEST------------ 536

318A1ps         -LQFVENISLKFNNVDDISLAIQP----------------- 544

18a1m           PSLKGNVGATITPESFKVCLKRRPLGPTAADPHHMRNVGAN 538

18a1ps          PSLKGNVGATITPEAFKVCLKRRPLAPTATDPHHMRNVGSN 539

306A1m          VDMAGESGITLTPTPHMLRFTKLPAVEMRHAPDGAVVQD-- 574

306A1ps         ADMEGECGITLAPAPYKLRFTKLPPMELQVEEQPLVQA--- 591

303a1m          PEEVPLEGATAAVKPYDIMLVAREQ---------------- 503

303A1ps         PEEVPLEGATAAVKPYEVMLVARTPEQEC------------ 507

305a1m          PSMVLLPGITLTPKPYKVQFVKRT----------------- 504

305A1ps         PSMVLLPGITLTPKPYKVKFVKRS----------------- 506

304a1m          LPDLSQNLNGLIISPPDFWLQLQDRH--------------- 510

304a1ps         LPDLSKNQNGLIITPPDFWVQLENRRCG------------- 512

307a1m          TIKISPESLALPADCFPLVLTPREKIGPL------------ 525

307a1ps         TIRITPASLALPASCFPLLLTRRA----------------- 532

307a2pm         -----------------------------------------

307a2pps        KININHESLALPADCFPLVLTPRA----------------- 561