This alignment contains 122 sequences and is 746 characters long
Numbers after CYP names refer to Fugu Scaffold numbers
There are 60 human 54 Fugu and 8 other fish sequences included. 

2C9       -------------------------MDS------------
2C19      -------------------------MDP------------
2C18      -------------------------MVP------------
2C8       -------------------------MEP------------
2E1       -------------------------MFALGV---------
2F1       -------------------------MDSI-----------
2W1       -------------------------MALL-----------
2B6       -------------------------MELS-----------
2A6       -------------------------MLASGML--------
2A7       -------------------------MLASGLL--------
2A13      -------------------------MLASGLL--------
2G1P      -------------------------MELGGAV--------
2G2P      -------------------------MEMGGAV--------
2M1  trout-------------------------MDVLHILQTN-----
2J2       -----------------------MLAAMGSLAAALWAVVH
2X2   4007-------------------------MV-------------
2X3       -------------------------ML-------------
2X1catfish-------------------------ML-------------
2V1  Danio---------------------MALENILLHLNSKVWTDAG
2Z2  2993b-------------------------MHWIFDLIGSFLAGD
2P3  killi-------------------------MEAIRSVLGLEWID-
2P4       -------------------------MEAILSTLGLEWMD-
2N2  killi-------------------------MWFYNLLLSLD----
2N11 3261c-------------------------MWPLQLLLDFD----
2N10 3261b-------------------------MWLYSVLSWD-----
2N12 3261d-------------------------MILQKIFAYMD----
2N9  3261a-------------------------MWLWDLVLWLRL---
2Y2  39b  -------------------------ME-------------
2R1  7138 --------------------MVPAQSPPLVPPSRDQALLG
2U1  8899 -------------------------MMSLSWLQSLSSS--
2U1       -------MSSPGPSQPPAEDPPWPARLLRAPLGLLRLDPS
2Z1  2993a-------------------------MGLIVSVFGSHADWS
2K9  12487-------------------------MIEDLFESSTSG---
2K6  Danio------------------------MALIEAFLLQGSPTGA
2Y1  39a  -------------------------MDLT-----------
2K10 19693-------------------------MSLQDFLLSLGPS--
2K11      ----------------------MGIVDLFLQASSSVSLLL
2R1       -------------------------MWKLWRAEEGAAA--
2S1       -------------------------MEATGT---------
2T2P      ----------------------------------------
2D6       ----------------------------MGLEALV-----
1A1       ----------------------MLFPISMSATEFL-----
1A2       --------------------MALSQSVPFSATELL-----
1B1       -----------MGTSLSPNDPWPLNPLSIQQTTLL-----
1B3  3008a-----------MG-DFGLKSSSITREWSGHV---------
1B2  3008b---------MALDTEFGVKSSSITREWSGQV---------
1B1  1553 -----------MKVIQEEVSPE------------------
17        ----------------------------------------
17A1 4175 -------------------------MDWV-----------
17A2 8086 ----------------------------------------
21        ----------------------------------------
21   15   -------------------------MCSFLFCSS------
3A4       -------------------------MAVIPDLAME-----
3A5       -------------------------MDLIPNLAVE-----
3A7       -------------------------MDLIPNLAVE-----
3A43      -------------------------MDLIPNFAME-----
3A47 600  -------------------------MNYLPLFALE-----
3B1  2213a-------------------------MFEFVLFSGT-----
3B2  2213b-------------------------MFVFMCFSAT-----
3A48      -------------------------MDLLPNFSIE-----
3A49      ----------------------------------------
3A50P     -------------------------MNFLPDFFLN-----
3A27 trout-------------------------MMSFLPYFSAE----
5A1       -------------------MEALGFLKLEVNGPMV-----
5A1  1244 -------------------MSQLIFNIKFLE---------
4A11      -------------------------MSVSVLSPSRLLGD-
4A22      -------------------------MSVSVLSPSRRLGG-
4A20      -------------------------MEPSWLQEL------
4B1       -------------------------MVPSFLSLS------
4F2       -----------------------MSQLSLSWLGLCDVAAS
4F3       -----------------------MPQLSLSSLGLWPMAAS
4F8       -----------------------MSLLSLSWLGLRPVAAS
4F11      -----------------------MPQLSLSWLGLGPVAAS
4F12      -----------------------MSLLSLPWLGLRPVAMS
4F22      ---------------------MLPITDRLLHLLGLEKTAF
4F28 2425 -------------------------MSVLQLALS------
4X1       -------------------------MEFSWLETRWAR---
4V2       -------------------------MAGLWLGLVWQK---
4V5  485  -------------------------MADLL----------
4T5  8637 -------------------------MEITRALVV------
4T2seabass-------------------------MELTEAFLTLH----
46        ----------------------------------------
46   4537 -------------------------MGVFNLIFGW-----
20        ----------------------------------------
20   486  ----------------------------------------
26A1      -------------------------MGLPALLA-------
26A1 12575-------------------------MAVSALLA-------
26B1 4267 --------------------MLFDSFDLVSALA-------
26C1 11741------------------------MLGLVSALA-------
26B1      -------------------------MLFEGLDLVSA----
26C1      -------------------------MFPWGLSCLSV----
11A1      --------------------------MLAKGLPPRSVLVK
11A1 1630 --------------------------MARWSVWRSPVVLP
11B1      --------------------------MALRA---------
11B2      --------------------------MALRA---------
11B1 fugu ----------------------MWLPAGAGVRARSARGFR
27A1      ---------------MAALGCARLRWAL---RGAGRGLCP
27A1 FUGU ---------------MSACLCVNSCGRK---EAGCCGLWP
27A2 697  --------------------------MASFTALR------
27A3      ----------------------MFRNRLLTVGLRASVPHR
27B1      --------------------------MT------------
27B1 470  --------------------------MLQQALRV------
27C1      ----MQTSAMALLARILRAGLRPAPERGGLLGGGAPRRPQ
27C1 1410 --------MSVMNKLTTTCWTNFYGDRRNKQMLFVLRCLH
24        ---------------MSSPISKSRSLAAFLQQLRSPRQPP
24   1804 ----------------------------------------
19        --------------------------MVLE----------
19ov 7098 --------------------------MAAVGLDAEVLV--
19br 4200 --------------------------MKPKE---------
8A1       -------------------------MAW------------
8A2  5061 ----------------------------------------
8A1  4451 ----------------------------------------
8B1       -------------------------MVLWGP---------
8B1  7782 -------------------------MASVLL---------
8B2  21917-------------------------MASLLL---------
7B1       ------------------------MAGEVSAATGRFSLER
7A1       --------------------------MMTTSLI---WGIA
7A1  5172 --------------------------MILSIA--LIWAVV
7C1  16085----------------------------------------
39A1      --------------------------MELISPT---VIII
51        -------------MAAAAGMLLLGLLQAG-GSVLGQ----
51   437  -------------MSAHLYEMSSKL---------------

2C9       ---LVV-LVLCLSCLL--L-LSLWR-------------QSSGRGKLPPGPTPL-PVIGNI--LQIGIKDI
2C19      ---FVV-LVLCLSCLL--L-LSIWR-------------QSSGRGKLPPGPTPL-PVIGNI--LQIDIKDV
2C18      ---AVA-LVLCLSCLF--L-LSLWR-------------QSSGRGRLPSGPTPL-PIIGNI--LQLDVKDM
2C8       ---FVV-LVLCLSFML--L-FSLWR-------------QSCRRRKLPPGPTPL-PIIGNM--LQIDVKDI
2E1       ---TVA-LLVWAAFLL--L-VSMWR-------------QVHSSWNLPPGPFPL-PIIGNL--FQLELKNI
2F1       ---STA-ILLLLLALV--C-LLLTL-------------SSRDKGKLPPGPRPL-SILGNL--LLLCSQDM
2W1       ---LLL-FLGLLGLWG--L-LCACA------------QDPSPAARWAPGLRPL-PLVGNL--HLLRLSQQ
2B6       ---VLL-FLALLTGLL--L-LLVQR-------------HPNTHDRLPPGPRPL-PLLGNL--LQMDRRGL
2A6       ---LVA-LLVCLTVMV--L-MSVWQ-------------QRKSKGKLPPGPTPL-PFIGNY--LQLNTEQM
2A7       ---LVA-LLACLTVMV--L-MSVWQ-------------QRKSKGKLPPGPTPL-PFIGNY--LQLNTEHI
2A13      ---LVT-LLACLTVMV--L-MSVWR-------------QRKSRGKLPPGPTPL-PFIGNY--LQLNTEQM
2G1P      ---TIF-LALRLSCLL--I-LIAWK-------------RMDKAGKLPPGPTPI-LFLGHL--LQVRTDAT
2G2P      ---TIF-LALCLSCLL--I-LIAWK-------------*MNKAGKLPPGPTPI-PFLGNL--LQVRTDAT
2M1  trout---FVS-IIIGFVVII--L-LWMNR-------------GKQSNSRLPPGPAPI-PLLGNL--LRMDVKAP
2J2       ---PRT-LLLGTVAFL--L-AADFL-------------KRRRPKNYPPGPWRL-PFLGNF--FLVDFEQS
2X2   4007---TSV-ILLCLGVVV--L-VL-LL-------------RSQRPKNFPPGPPVL-PLLGSI--LELALDNP
2X3       ---VSL-ALLLAAAFG--L-WV-FF-------------QIQRPKNFPPGPPPI-PLFGNL--LEIQLDNP
2X1catfish---GSW-LLVVFCVCL--L-FL-FI-------------RIQRPKNFPPGPRPI-PIFGNL--FQFNIKNP
2V1  Danio---TIL-LLFILFLLV--S-VKLRN-------------RNKPTKTFLLGPTPL-PFIGNV--FNLDTSQP
2Z2  2993b---FKS-LLFFLLIFI--L-TADYL-------------RNRRSGSFPPGPMAI-PIIGNM--LSLDRSRT
2P3  killi---ARG-VLLFFFVFL--L-LSDVL-------------RNRKPKNFPPGPLAL-PFIRDL--HRIRPARL
2P4       ---GRT-ILIFLLVFV--L-LADYI-------------KNRVPSNFPPGPWPL-PLIGDL--HRINPSRL
2N2  killi---VKG-LFLFIFLFL--L-IADFY-------------KSRKPANFPPGPKAL-PFVGNF--FSLDSKHP
2N11 3261c---IRA-LLLFISVLL--L-IGDYF-------------RYKNPPNFPPGPMSL-PFVGSF--FSVDSKHP
2N10 3261b---FTS-LLLFFFVLI--L-FANYL-------------KNRDPPNFPPGPFAF-PIVGNF--FTMDSKNL
2N12 3261d---FSS-WVLLIFLVL--L-ITDVI-------------RNWTPHNFPPGPWAM-PFVGNI--FTGVD---
2N9  3261a---TGF-LLPVLIVLL--I-IMYSL-------------RQKDPPNFPPGPPAL-PLLGNI--FNIEAKQP
2Y2  39b  ---FSV-TLILAGLVL--A-FFWFI-------------LQKRKYNLPPGPTTL-PLVGNL--PQLDKKQP
2R1  7138 ---LAC-LTVAFLAVL--L-VRQLV-------------KQRRPPGFPPGPSPI-PIIGNI--MSLAT-EP
2U1  8899 ---ILT-LVIMIILHH--L-FKCYQ-------------KRHGFANIPPGPKPW-PVVGNF---GGFL-NA
2U1       ---GGA-LLLCGLVAL--L-GWSWL-------------RRRRARGIPPGPTPW-PLVGNF---GHVLLPP
2Z1  2993a---IST-LLLFTAVFI--L-MVNWI-------------RNRRPPSFPPGPWTL-PVVGNM--HNLAHHRM
2K9  12487---FLM-VAIVSLLLL--Q-LCFSF-------------ISREKRKDLPGPEAL-PLLGNL--HQLDLKRL
2K6  Danio---ILG-ALLLFLVIY--L-FSSSS-------------SSQDKEKYPPGPKPL-PLLGNL--HILDLKKT
2Y1  39a  ---VML-LTATLLLVV--L-WILNA-------------HTRKHTRLPPGPRGI-PVLGNL--LQLDKKAP
2K10 19693---TLM-GSVALLLLL--C-LVSRS-------------FGRATRREPPGPRAL-PLLGNL--LQLDLSRP
2K11      ---LGA-LALLLFVYF--I-SSVSF-------------SSKKDRKCPPGPKPL-PILGNL--LQFDLKRP
2R1       ---LGG-ALFLLLFAL--G-VRQLL-------------KQRRPMGFPPGPPGL-PFIGNI--YSLAASSE
2S1       ---WAL-LLALALLLL--L-TLALS-------------GTRARGHLPPGPTPL-PLLGNL--LQLRPGAL
2T2P      --------------------------------------RAQMRGSLPPRPRPL-PLLGNL---QLQSGGL
2D6       ---PLA-VIVAIFLLL--V-DLMHR-------------RQRWAARYPPGPLPL-PGLGNL--LHVDFQNT
1A1       ---LAS-VIFCLVFWV--I-RASRP-------------QVPKGLKNPPGPWGW-PLIGHM--LTLG-KNP
1A2       ---LAS-AIFCLVFWV--L-KGLRP-------------RVPKGLKSPPEPWGW-PLLGHV--LTLG-KNP
1B1       ---LLL-SVLATVHVG--Q-RLLRQ-------------RRRQLRSAPPGPFAW-PLIGNA--AAVG-QAA
1B2  3008a---QPA-LVAFFVFLF--C-VEACL-------------WAKNLKRRLPGPFAW-PVVGNA--MQLG-QMP
1B3  3008b---QPA-LVASFLFLF--C-LEACL-------------WVRNLKRRLPGPFAW-PVVGNA--MQLG-QMP
1B1  1553 ---AGA-LLLACATLLV-S-LQLWR-------------WRRRRPGCPPGPRAW-PIIGNA--AQLG-HAP
17        --MWEL-VALLLLTLA--Y-LFWPK-------------RRCPGAKYPKSLLSL-PLVGSL-PFLPRHGHM
17A1 4175 LFVYAF-SAVNLALLA--L-HLKFR-------------TPASGPRGPPRLPAL-PLIGSL-LSLRSPHPP
17A2 8086 MVTVGS-FLIFRRPVR--G-SEPGS-------------EAGPPRVKVPCISWV-PVLGSL-PWLRGGRPL
21        -------MLLLGLLLL--P-LLAGA-------------RLLWNWWKLRSLHLPPLAPGFL--HLLQPDL-
21   15   ---FSA-PPAVKRNLP--L-SLWQL-------------PLRPSSPPIPGPPCR-FLIGNM--TELMHDHL
3A4       --TWLL-LAVSLVLLY--L-YGTHS-------------HGLFKKLGIPGPTPL-PFLGNI--LSY-HKGF
3A5       --TWLL-LAVSLVLLY--L-YGTRT-------------HGLFKRLGIPGPTPL-PLLGNV--LSY-RQGL
3A7       --TWLL-LAVSLILLY--L-YGTRT-------------HGLFKKLGIPGPTPL-PFLGNA--LSF-RKGY
3A43      --TWVL-VATSLVLLY--I-YGTHS-------------HKLFKKLGIPGPTPL-PFLGTI--LFY-LRGL
3A47 600  --TWIL-LITFTCLFV--M-YGKRT-------------FGIFEKLGISGPKPT-MYFGSI--CKY-NN-V
3B1  2213a--TWAL-LALFFALLL--L-YGVWP-------------YHHFKKLGIRGPRPL-PFMGST--FYY-RKGI
3B2  2213b--TWTI-LVLFSTLLL--L-YGHWP-------------YRLFRKNGIPGPMPL-PFIGTM--WNL-LKGN
3A48      --TWTL-LTLIFTLII--V-YGYAP-------------YGFFKKVGIPGPKPW-PFIGTF--LNY-RRGI
3A49      --------------------YGYAP-------------YGFFKKVGISGPKPW-PFIGTF--LNY-KKGV
3A50P     --TWTF-LILVIVLST--T----------------------IKRVGIRGPTPWAPLIGD---IFY-----
3A27 trout--TWTL-LALLITLIV--V-YGYWP-------------YGVFTKMGIPGPKPL-PYFGTM--LEY-KKGF
5A1       --TVAL-SVALLALLK--W-YSTSA-------------FSRLFKLGLRHPKPS-PFIGNL--TFF-RQGF
5A1  1244 --VTIR-LSVNTVLSF--R-YSVRP-------------FSVLSRNGIKHPKPL-PFFGNL--FMF-RQGF
4A11      VSGILQ-AASLLILLLLL----IKAVQLYLHRQ-----WLLKALQQFPCPPSH-WLFGHIQELQQD-QEL
4A22      VSGILQ-VTSLLILLLLL----IKAAQLYLHRQ-----WLLKALQQFPCPPSH-WLFGHIQEFQHD-QEL
4A20      MAHPFL-LLILLCMSLLL----FQVIRLYQRRR-----WMIRALHLFPAPPAH-WFYGHKEFYPVK-EFE
4B1       FSSLGL-WASGLILVLGF----LKLIHLLLRRR-----TLAKAMDKFPGPPTH-WLFGHALEIQET-GSL
4F2       --PWLL-LLLVGASWLLA----HVLAWTYAFYD-----NCRRLRCFPQPPRRN-WFWGHQGMVNPTEEGM
4F3       --PWLL-LLLVGASWLLA----RILAWTYTFYD-----NCCRLRCFPQPPKRN-WFLGHLGLIHSSEEGL
4F8       --PWLL-LLVVGASWLLA----RILAWTYAFYH-----NGRRLRCFPQPRKQN-WFLGHLGLVTPTEEGL
4F11      --PWLL-LLLVGGSWLLA----RVLAWTYTFYD-----NCRRLQCFPQPPKQN-WFWGHQGLVTPTEEGM
4F12      --PWLL-LLLVVGSWLLA----RILAWTYAFYN-----NCRRLQCFPQPPKRN-WFWGHLGLITPTEEGL
4F22      -RIYAVSTLLLFLLFFLFRLLLRFLRLCRSFYI-----TCRRLRCFPQPPRRN-WLLGHLGMVSPNEAGL
4F28 2425 -WTSVCPLLAVLAAAPVALLTFWTAKLLVRHAW-----YTHRMACFSKPHARS-WLLGHLGQMQSTEEGL
4X1       --------PFYLAFVFCLALGLLQAIKLYLRRQ-----RLLRDLRPFPAPPTH-WFLGHQKFIQDDNMEK
4V2       ---LLLWGAASAVSLAGASLVLSLLQRVASYAR-----KWQQMRPIPTVARAY-PLVGHA--LLMKPDGR
4V5  485  ---GGFTLPLLGASVFVAALTCFTYRMLSDYLH-----KWFQMKPIPELEGTY-PLIGNA--LQFKPNAG
4T5  8637 ---LGWSHFYQLLALFCLAIVLYKLTVLLMLKR-----ALIRNFESFPGPPGH-WLFGNI--LEFKQDGN
4T2seabass---WGLPRLHHLLALLCLVAVVYKLATLLAKRR-----DVFRSYEDFPGPPTH-WLFGHV--LEFKQDGT
46        ---------MSPGLLLLGSAVLLAFGLCCTFVH-----RARSRYEHIPGPPRPSFLLGHLPCFWKKDEVG
46   4537 ---------ISQASIFLLLLLFIALLGYCMYIK-----YTHMKYDHIPGPPRDSFFSGHSSKLLDIMKDD
20        ----------MLDFAIFAVTFLLALVGAVLYLY-----PASRQAAGIPGITPTEEKDGNLP-DIVNSGSL
20   486  ----------MLDFAIFAVTFVIVLVGAVLYLY-----PSSRRASGIPGLNPTDEKDGNLQ-DIVGRGSL
26A1      SALCTF-VLPLLLFLAAL----KLWDLYCVSSR-----DRSCALPLPPGTMGF-PFFGET--LQM-VLQR
26A1 12575TFLCTI-VLPLLLFLVTV----KLWEVYVIRER-----DSACPSPLPPGTMGL-PFIGET--LQL-ILQR
26B1 4267 TLAACL-VSMALLLAVSQ----QLWQLRWTATR-----DRNCKLPMPKGSMGF-PFIGET--CHW-LLQG
26C1 11741TALTTL-LLLLLLLALTR----QLWSFRWSLTR-----DRRCELPLPKGSMGW-PLVGET--FQW-LFQG
26B1      LATLAACLVSVTLLLAVS---QQLWQLRWAATR-----DKSCKLPIPKGSMGF-PLIGET--GHW-LLQG
26C1      LGAAGTALLCAGLLLSLA---QHLWTLRWMLSR-----DRASTLPLPKGSMGW-PFFGET--LHW-LVQG
11A1      GYQTFL-SAPREGLGRLRVPTGEGAGIS-TRSP-----RPFNEIPS-PGDNGW-LNLYHF-WRETGTHKV
11A1 1630 LSRMEV-PMTGARHSSTMPVARQTYSDS-SSFV-----RSFNDIPG-LWKNGV-ANLYNF-WKLDGFRNL
11B1      KAEVCM-AVPWLSLQRAQALGTRAARV--PRTV-----LPFEAMPR-RPGNRW-LRLLQI-WREQGYEDL
11B2      KAEVCV-AAPWLSLQRARALGTRAARA--PRTV-----LPFEAMPQ-HPGNRW-LRLLQI-WREQGYEHL
11B1 fugu TAAGAV-VDGKVGACKGAEVPESKKGV--DGQV-----RSFEEIPH-TGRNSW-VNLLRF-WREDRFRHL
27A1      HGARAK-AAIPAALPSDKATGAPGAGPGVRRRQ-----RSLEEIPR-LGQ----LRFFFQ-LFVQGYAL-
27A1 3437 --------GLAPAPGAQGGSPQSQRLPPISASN-----HGRWRTFH-ASA----SGSCLQ-INVSGFHS-
27A2 697  CAAIGA-RNSALRPATLPSRNLNLQATSEAANL-----KGIADLPG-PNT----YKILYW-LFVKGYGE-
27A3      EGLHRT-AVNYAGARRRHASSAATEITEHNVRQ-----KTMEDLGG-PSF----LTTLNW-LFLKGYLP-
27B1      QTLKYA-SRVFHRVRWAPELGASLGYREYHSAR-----RSLADIPG-PST----PSFLAE-LFCKGGLS-
27B1 470  SCRSAS-PLVKWMERWAECASARPQAV-----------KPLGDMPG-PSV----ASFAWD-LFAKRGLS-
27C1      PAGARL-PAGARAEDKGAGRPGSPPGGGRAEGP-----RSLAAMPG-PRT----LANLAE-FFCRDGFS-
27C1 1410 KSATSG-TFGVAREEPLPERLITSTDATKKRLP-----KTLAEMPG-PGT----ISNLFE-FFWRDGFS-
24        RLVTST-AY-TSPQPREVPVCPLTAG-GETQN------AAALPGPT-SWPLLA-SLLQIL-WKGGLK---
24   1804 --------------MLWRLRGALTLP-PELTV------LDAIPGPT-NWPLVG-SLFELL-RKGGLT---
19        ---MLN-PIHYNITSIVPEAMPAATMSVLLLTGLFLLLWNYEGTSSIPGPGYC-MGIGPL--ISH-GRFL
19ov 7098 ---SVS-PNATEAESPGSSAGTRALIILTCLLLLVWSHTEKKSVPSLLGPSFC-LGFGPL--LTY-VRFI
19br 4200 ---TLN-ITASGPFTPLPLPLMMMMMMLLLMMMMLFLTWNRPQRQHVPGPLFL-AGLGPL--LSY-CRFM
8A1       --AALL-GLLAALLLLL----------LLSRRR-------TRRPGEPPLDLGSIPWLGYA--LDF-GKDA
8A2  5061 --MIWA-ALLGGLLTLV----------LLYFSR-------RRQDNEPPLDKGALPWLGHA--LEF-GRDA
8A1  4451 --MIWT-VLLLVHALL-----------LYFILR-------HRSRNEPPLDKGLIPWLGHA--LEF-GKDA
8B1       --VLGA-LLVVIAGYLC----------LPGMLR-------QRRPWEPPLDKGTVPWLGHA--MAF-RKNM
8B1  7782 --ILLT-FLVALLGGLY----------LLGVFR-------QRRPGEPPLDKGLIPWLGHV--LEF-RRNT
8B2  21917--ILLT-FLVALLGALY----------LLGVFR-------QRRPGEPPLDKGLIPWLGHV--LEF-CRNT
7B1       --LGLP-GLALAAALLLLALC------LLVRR--------TRRPGEPPLIKGWLPYLGVV--LNL-RKDP
7A1       IAACCC-LWL-----------------ILGIR--------RRQTGEPPLENGLIPYLGCA--LQF-GANP
7A1  5172 VGFCCL-LWL-----------------AVGIR--------HRHSSEPPVENGLIPYLGCA--LQF-GANP
7C1  16085----------------------------------------------------------------------
39A1      ---LGC-LAL-----------------FLLLQ--------RKNLRRPPCIKGWIPWIGVG--FEF-GKAP
51        --AMEKVTGGNLLSMLLIACAFTLSLVYLIRLAAGHLVQLPAGVKSPPYIFSPIPFLGHA--IAF-GKSP
51   437  --IGDTVGRVHDNLTTVVLAASFITLSLGYVSKLLLRQSFVTDAKHPPYIPSCIPFLGHA--ISF-GKSP

2C9       ----SKSLTNLSK--VYG------PVFTLYFGL-KPIVVLHGYEAVKEAL-IDLGEEFSG-----------
2C19      ----SKSLTNLSK--IYG------PVFTLYFGL-ERMVVLHGYEVVKEAL-IDLGEEFSG-----------
2C18      ----SKSLTNFSK--VYG------PVFTVYFGL-KPIVVLHGYEAVKEAL-IDHGEEFSG-----------
2C8       ----CKSFTNFSK--VYG------PVFTVYFGM-NPIVVFHGYEAVKEAL-IDNGEEFSG-----------
2E1       ----PKSFTRLAQ--RFG------PVFTLYVGS-QRMVVMHGYKAVKEAL-LDYKDEFSG-----------
2F1       ----LTSLTKLSK--EYG------SMYTVHLGP-RRVVVLSGYQAVKEAL-VDQGEEFSG-----------
2W1       ----DRSLMELSE--RYG------PVFTVHLGR-QKTVVLTGFEAVKEAL-AGPGQELAD-----------
2B6       ----LKSFLRFRE--KYG------DVFTVHLGP-RPVVMLCGVEAIREAL-VDKAEAFSG-----------
2A6       ----YNSLMKISE--RYG------PVFTIHLGP-RRVVVLCGHDAVREAL-VDQAEEFSG-----------
2A7       ----CNSIMKFSE--CYG------PVFTIHLGP-RRVVVLCGHDAVREAL-VDQAEEFSG-----------
2A13      ----YNSLMKISE--RYG------PVFTIHLGP-RRVVVLCGHDAVKEAL-VDQAEEFSG-----------
2G1P      ----FQSFMKLRE--KYS------PVFTVYMGP-RPVVVLCGHEAVKEAL-IDQADEFSG-----------
2G2P      ----FQSFMKLRE--KYS------PVFTVYMGP-RPVVVLCGHEAVKEAL-VDQADEFSG-----------
2M1  trout----YKLYMELSK--KYG------SVFTVWLGS-KPVVVISGYQAIKDAF-VTQGEEFSG-----------
2J2       ----HLEVELFVK--KYG------NLFSLELGD-ISAVLITGLPLIKEAL-IHMDQNFGN-----------
2X2   4007----LQDFERLRK--KYG------NVYSLFLGT-RPAVVISGLKNIKEAL-VTKGSDFSG-----------
2X3       ----IADLERLAK--RYG------NVYGLFLGS-RPAVVINGVSAL-------------------------
2X1catfish----LKDFEKLAE--QYG------NICSLYIGT-KPAVVLNGLKVIREAL-VTKSADFSG-----------
2V1  Danio----HICLTKMSD--HYG------NIFSLRLGS-LNTVVVNTYSMVKKVL-NDQGNSFMY-----------
2Z2  2993b----HESLTQLAE--TYG------NVYSLRTGQ-TWMVVVNSFKVVREAL-VTHGESVSD-----------
2P3  killi----HLQLTEFAE--TYG------DIYSLHLFG-GRAVIINGYKHVKEAL-VQKGEDFMD-----------
2P4       ----HLQFAEFAG--KYG------NIFSLRLFG-GRVVVLNGYKTVREAL-VEKGENFVD-----------
2N2  killi----HVYFQKLAE--IYG------NVFSFRLGR-DSIVFLNGYKAVREAL-VTQAENFVD-----------
2N11 3261c----HNYFIQMAE--LYG------KLFSIRLGS-GKIVFACGYKMVKEAI-VTQADNFVD-----------
2N10 3261b----HLYFNKLAD--VHG------NVFSFRLGG-DKMVCVSGHKMVKEAI-VTQADNFVD-----------
2N12 3261d----FRTIEKLSQ--KYG------PVFSLRRGN-TRTVFINGYKMVKEAL-VSQLDSFED-----------
2N9  3261a----HLYLTKLAD--VYG------SVFCIRLGR-HKTVFVSGWKMVKEAI-VTQADSFVD-----------
2Y2  39b  ----FKSFTELSK--SYG------PVMTLYLGW-QRTVVLTGYEVVKEAL-VDQAEDFTG-----------
2R1  7138 ----HVFLKKQSE--VHG------QIFSIDLGG-ILTVVLNGYDCIRECL-YNQSEVFAD-----------
2U1  8899 ----AAVLTELAK--VYG------NVYSIYVGS-QLVVVLNGYKVVRDAL-SNHPDVFSD-----------
2U1       ----QVLLAHLAR--VYG------SIFSFFIGH-YLVVVLSDFHSVREAL-VQQAEVFSD-----------
2Z1  2993a----HLNLMELAE--TYG------NVFSIQLGQ-EWMVVLNGPTILKEAL-VNQGDSVAD-----------
2K9  12487----DCHLVQLSQ--KYG------PIFRVYLAS-KKVVVLAGYTAVKQAL-VNQAEDFGE-----------
2K6  Danio----YLSLLELSK--KYG------PIYTVYLGP-KKVVILSGYKIVKEAL-VNLSEEFGD-----------
2Y1  39a  ----FKSLLKLSE--NYG------PVLTVALGP-QRTVVLVGYEAVKDAL-VDHADDFTG-----------
2K10 19693----HQTLYQLSK--KYG------PVFKVHFGP-RKVVVLAGHKTVKEAL-VGNAEQFGD-----------
2K11      ----YNTLMKLSK--TYG------SVFTVYLGP-KKVVVLAGYKTVKEAL-IDHAEEFGE-----------
2R1       --LPHVYMRKQSQ--VYG------EIFSLDLGG-ISTVVLNGYDVVKECL-VHQSEIFAD-----------
2S1       ----YSGLMRLSK--KYG------PVFTIYLGPWRPVVVLVGQEAVREAL-GGQAEEFSG-----------
2T2P      ----DRALHSLSG--RWG------RVFTVRLGP-RPAVGLCGYAALRDAL-VLQADAVSG-----------
2D6       ----PYCFDQLRR--RFG------DVFSLQLAW-TPVVVLNGLAAVREAL-VTHGEDTAD-----------
1A1       ----HLALSRMSQ--QYG------DVLQIRIGS-TPVVVLSGLDTIRQAL-VRQGDDFKG-----------
1A2       ----HLALSRMSQ--RYG------DVLQIRIGS-TPVLVLSRLDTIRQAL-VRQGDDFKG-----------
1B1       ----HLSFARLAR--RYG------DVFQIRLGS-CPIVVLNGERAIHQAL-VQQGSAFAD-----------
1B2  3008a----HITFSKLAK--KYG------NVYQIRLGC-SDIVVLNGARVIRQAL-IEHSTEFAG-----------
1B3  3008b----HITFAKLAK--KYG------NVYQIRLGC-SNIVVLNGDQAIHQAL-IEHSTEFAG-----------
1B1  1553 ----HLYFTRMAQ--RFG------NVFQIKLGS-RTVVVLNGD-AIKQAL-VRKGLEFAG-----------
17        ----HNNFFKLQK--KYG------PIYSVRMGT-KTTVIVGHHQLAKEVL-IKKGKDFSG-----------
17A1 4175 ----HVLFKELQG--KYG------QTYSLMMGS-HRVIIVNHHAHAKEVL-LKKGKIFAG-----------
17A2 8086 ----HLIFTQLSY--RYG------PLFALYLGP-HLTVVVNNHQHAREVL-LLRGKDFAG-----------
21        ----PIYLLGLTQ--KFG------PIYRLHLGL-QDVVVLNSKRTIEEAM-VKKWADFAG-----------
21   15   ----PIHLTNLAK--RYG------NIYRLKCGNTTAMIVLNSSDIIREAL-VKKWSDFAG-----------
3A4       ----CMFDMECHK--KYG------KVCGFYDGQ-QPVLAITDPDMIKTVL-VK--ECYSV-----------
3A5       ----WKFDTECYK--KYG------KMWGTYEGQ-LPVLAITDPDVIRTVL-VK--ECYSV-----------
3A7       ----WTFDMECYK--KYR------KVWGIYDCQ-QPMLAITDPDMIKTVL-VK--ECYSV-----------
3A43      ----WNFDRECNE--KYG------EMWGLYEGQ-QPMLVIMDPDMIKTVL-VK--ECYSV-----------
3A47 600  ----YYLDQECAQ--KYG------KIWGTYELR-KPMLVVMDPDLLKTIL-VK--ECFTH-----------
3B1  2213a----IPFESWCQA--EYG------DVWGMFEGR-TPVLMVSDPEILKTVL-VK--ECYSV-----------
3B2  2213b----MVFDRECQS--KYG------DVWGVFEGR-TPVLMVSDPGMIKTIL-VK--ECYSV-----------
3A48      ----HHFDEECYK--KYG------KVWGLYDGR-QPLMCIMDTGMIKTVL-VK--ECYSN-----------
3A49      ----HHFDEECYK--KYG------KVWGLYDGR-QPLMCIMDTGIIKTIL-VK--ECYSN-----------
3A50P     ----STRRGKCCK--RYG------KVWGLYEGR-IPVMFIVDTAMIKTVF-VK--EGYSV-----------
3A27 trout----TNFDTECFQ--KYG------RIWGIYDGR-QPVLCIMDKSMIKTVL-IK--ECYNI-----------
5A1       ----WESQMELRK--LYG------PLCGYYLGR-RMFIVISEPDMIKQVL-V---ENFSN-----------
5A1  1244 ----FNPLNDLIK--THG------RVCGYYLGR-KPVVVVADPEMLRQVM-V---KDFSS-----------
4A11      ----QRIQKWVET--TFP------SACPHWLWGGKVRVQLYDPDYMKVIL-GR--SDPKS-----------
4A22      ----QRIQERVKT---FP------SACPYWIWGGKVRVQLYDPDYMKVIL-GR--SDPKS-----------
4A20      -----VYHKLME---KYP------CAVPLWVGPFTMFFSVHDPDYAKILL-KR--QDPKS-----------
4B1       ----DKVVSWAH---QFP------YAHPLWFGQFIGFLNIYEPDYAKAVY-SR--GDPKA-----------
4F2       ----RVLTQLVA---TYP------QGFKVWMGPISPLLSLCHPDIIRSVI-NA--SAAIA-----------
4F3       ----LYTQSLAC---TFG------DMCCWWVGPWHAIVRIFHPTYIKPVL-FA--PAAIV-----------
4F8       ----RVLTQLVA---TYP------QGFVRWLGPITPIINLCHPDIVRSVI-NT--SDAIT-----------
4F11      ----KTLTQLVT---TYP------QGFKLWLGPTFPLLILCHPDIIRPIT-SA--SAAVA-----------
4F12      ----KNSTQMSA---TYS------QGFTIWLGPIIPFIVLCHPDTIRSIT-NA--SAAIA-----------
4F22      ----QDEKKVLD---NMH------HVLLVWMGPVLPLLVLVHPDYIKPLL-GA--SAAIA-----------
4F28 2425 ----LQVDELVQ---MFT------YCCSWFIGPFYHLVRVFHPDYVKPLL-MA--PASIV-----------
4X1       ----LEEIIE-----KYP------RAFPFWIGPFQAFFCIYDPDYAKTLL-SR--TDPKS-----------
4V2       EFFQQIIEYTEEY--RHM------PLLKLWVGPVPMVALYNAENVEGILT-SS--KQIDK-----------
4V5  485  DFFNQIVEYTREN--YHR------PLFKIWVGPVPFVVLFHPETVEPVLT-NA--VHMEK-----------
4T5  8637 ---DLDKLVKFGQ--KYP------YCFPLWFGPFVFLNIHHPEYVKTILA-ST------E-----------
4T2seabass---DFDTLMAWTK--QYP------YAFPLWFGPFCVLNIHHPDYVKTILA-ST------E-----------
46        GRVLQDVFLDWAK--KYG------PVVRVNVFHKTSVIVTSPESVKKFLM-ST--KYNKD-----------
46   4537 G-VVHDMFLKWAE--TYG------PVYKIYFLHHVMVFVSCPETTKEMLM-SP--KYTKD-----------
20        ----HEFLVNLHE--RYG------PVVSFWFGRRLVVSLGTVDVLKQHIN-PN--KTSDP-----------
20   486  ----HEFLVSLHQ--EFG------PVASFWFGSRPVVSLGSLQQLRQHIN-PN--HSTDS-----------
26A1      ----RKFLQMKRR--KYG------FIYKTHLFG-RPTVRVMGADNVRRIL-LG--DDRLVS----------
26A1 12575----RKFLRMKRQ--KYG------YIYRTHLFG-NPTVRVTGANNVRHIL-LG--EHRLVA----------
26B1 4267 ----SGFHASRRQ--KYG------NVFKTHLLG-RPLIRVTGAENIRKVL-MG--EHTLVT----------
26C1 11741----SNFHISRRK--RHG------NVFKTHLLG-KPLVRVTGAENIRKIL-LG--EHSLVC----------
26B1      ----SGFQSSRRE--KYG------NVFKTHLLG-RPLIRVTGAENVRKIL-MG--EHHLVS----------
26C1      ----SRFHSSRRE--RYG------TVFKTHLLG-RPVIRVSGAENVRTIL-LG--EHRLVR----------
11A1      ----HLHHVQNFQ--KYG------PIYREKLGN-VESVYVIDPEDVALL--FKSEGP--------------
11A1 1630 ----HHIMVQNFN--TFG------PIYREKIGY-YESVNIINPEDAAIL--FKAEGH--------------
11B1      ----HLEVHQTFQ--ELG------PIFRYDLGG-AGMVCVMLPEDVEKL--QQVDSL--------------
11B2      ----HLEMHQTFQ--ELG------PIFRYNLGG-PRMVCVMLPEDVEKL--QQVDSL--------------
11B1 fugu ----HKHMERNFN--SLG------PIYREPVGA-PNSVNIMLPSDISEL--SRSEGL--------------
27A1      --QLHQLQVLYKA--KYG------PMWMSYLGP-QMHVNLASAPLLEQV--MRQEGK--------------
27A1 3437 --HMHELQILEKG--RYG------PIYR---NG-MNAVSVSTAKLLGEV--LRNDDK--------------
27A2 697  --RSHLLQGKLKN--IYG------PMWRWKLGP-YDFVSVASPELIARV--IQQEGR--------------
27A3      --KTQQMQVEHSK--IYG------PLWKSKYGP-MVVVNVASADLIEQV--LRQEGR--------------
27B1      --RLHELQVQGAA--HFG------PVWLASFGT-VRTVYVAAPALVEEL--LRQEGP--------------
27B1 470  --RLHELQLEGVR--RYG------PMWKASFGP-ILTVHVADPALIEQV--LRKEGQ--------------
27C1      --RIHELQQKHTR--EYG------KIFKSHFGP-QFVVSIADRDMVAQV--LRAEGA--------------
27C1 1410 --RIHEIQIEHSK--MYG------KIFKSRFGP-QLVVSVADRDLVAEV--LRAEGV--------------
24        --KQHDTLVEYHK--KYG------KIFRMKLGS-FESVHLGSPCLLEAL--YRTESV--------------
24   1804 --RQHEALVDYHK--KFG------KIFRLKLGS-FESVHIGAPCLLESL--YRTEGS--------------
19        WMGSRSACNYYNR--VYG-----EFMRVWISGE-ETLIISKSSSMFH-I--MKHNHYSSRFG---------
19ov 7098 WTGIGTASNYYNK--KYG-----DIVRVWVNGE-ETLVISRASAVHH-V--LKSRQYTSRFG---------
19br 4200 WTGIGTACNFYNN--KYG-----SLVRVWINGE-ETLILSRSSAVYH-V--LRSAHYTARFG---------
8A1       ----ASFLTRMKE--KHG-----DIFTILVGG--RYVTVLLDPHSYD-A--VVWEPRTRL-----------
8A2  5061 ----AKFLARMKE--KHG-----DVFTVRVAG--QYITVLLDANSFD-S--VLNDTVSL------------
8A1  4451 ----SKFLERMKR--KHG-----DIFTVRAAG--RYVTVLLDPHSYD-Q--VIHDQDCL------------
8B1       ----FEFLKRMRT--KHG-----DVFTVQLGG--QYFTFVMDPLSFGPI--LKDTQRKL------------
8B1  7782 ----WRFLERMEK--KHG-----DVFTVQLAG--FYITFIQDPMSFGAF--VKESREKL------------
8B2  21917----WRFLERMEK--KHG-----DVFTVQLAG--FYITFIQDPMSFGAF--VKESREKL------------
7B1       ----LRFMKTLQK--QHG-----DTFTVLLGG--KYITFILDPFQYQLV--IKNHKQLS------------
7A1       ----LEFLRANQR--KHG-----HVFTCKLMG--KYVHFITNPLSYHKV--LCHGKYFD------------
7A1  5172 ----LQFLRSRQK--KYG-----HIFTCKIAG--QYIHFLCDPFSYHSV--IRQGRHLD------------
7C1  16085--------------------------SCAPAG--KYMTFIMDPLMYPNI--IKHGRQLD------------
39A1      ----LEFIEKARI--KYG-----PIFTVFAMG--NRMTFVTEEEGINVFL-KSKKVDF-------------
51        ----IEFLENAYE--KYG-----PVFSFTMVG--KTFTYLLGSDAAALLF-NSKNEDLNA-----------
51   437  ----IEFLENAYE--KYG-----PVFSFTMVG--STFTYLLGSDAAALLF-NSKNEDLNA-----------

2C9       -----RGI-FPLAERANR-------GFG-IVFS--NGKKWKEIRRFSLMTLRNFGMGK---------RSIE
2C19      -----RGH-FPLAERANR-------GFG-IVFS--NGKRWKEIRRFSLMTLRNFGMGK---------RSIE
2C18      -----RGS-FPVAEKVNK-------GLG-ILFS--NGKRWKEIRRFCLMTLRNFGMGK---------RSIE
2C8       -----RGN-SPISQRITK-------GLG-IISS--NGKRWKEIRRFSLTTLRNFGMGK---------RSIE
2E1       -----RGD-LPAF-HAHR-------DRG-IIFN--NGPTWKDIRRFSLTTLRNYGMGK---------QGNE
2F1       -----RGD-YPAFFNFTK-------GNG-IAFS--SGDRWKVLRQFSIQILRNFGMGK---------RSIE
2W1       -----RPP-IAIFQLIQR-------GGG-IFFS--SGARWRAARQFTVRALHSLGVGR---------EPVA
2B6       -----RGK-IAMVDPFFR-------GYG-VIFA--NGNRWKVLRRFSVTTMRDFGMGK---------RSVE
2A6       -----RGE-QATFDWVFK-------GYG-VVFS--NGERAKQLRRFSIATLRDFGVGK---------RGIE
2A7       -----RGE-QATFDWVFK-------GYG-VAFS--NGERAKQLLRFAIATLRDFGVGK---------RGIE
2A13      -----RGE-QATFDWLFK-------GYG-VAFS--NGERAKQLRRFSIATLRGFGVGK---------RGIE
2G1P      -----RGE-LASIKQNFQ-------GHGGVALA--NGERWRILRRFSLTILRDFGMGK---------QSIK
2G2P      -----RGE-LASIKQNFQ-------GHG-VALA--NGERWRIL*RFPLTILRDFGMGK---------RSIE
2M1  trout-----RAN-YPVIMTVSK-------GYG-VLVS--SGKRSKDLRRFSLMTLKTFGMGR---------RSIE
2J2       -----RPV-TPMREHIFK-------KNG-LIMS--SGQAWKEQRRFTLTALRNFGLGK---------KSLE
2X2   4007-----RPQDMILSIDAIK-------TNV-IMQD--YNLVWKEHRRFALTTMRNFGMGK---------TSME
2X3       ----------------------------LLLSP--YNSGWREHRRFTLMTLRNFGLGK---------QSME
2X1catfish-----RPQNMLKDVTEGK-------GIV-IA-D--YGRQWKEHRRFALMTLRNFGLGK---------QSME
2V1  Danio-----RPSNDITERILSK-------CQG-LTFN--NGYSWKQHRRFTLSTLKFFGVGK---------RSLE
2Z2  2993b-----RPD-LPLQDEIAH-------GKG-VISS--NGHLWKQQRRFALSTLRLFGFGK---------KSLE
2P3  killi-----RPN-IPLFADFFN-------NKG-LVMS--NGYQWKVQRRFALHTLRNFGLGK---------KAME
2P4       -----RPL-IPLFEAFAG-------NRG-LVIS--NGNPWKHQRRFALHTLRNFGIGK---------KSLE
2N2  killi-----RPFNAITDRFYTEP------SAG-IFMS--NGEKWKKQRRFALSTLRNFGLGK---------NSLE
2N11 3261c-----RPF-NAFGDRIYMGQ-----RDG-LFQN--NGEVWKRQQHFALSTLRNFGLGK---------NILE
2N10 3261b-----RPY-DPISARVYGGQ-----TDG-LFQS--NGEVWKRQRRFALSTLRNFGLGK---------NILE
2N12 3261d-----RPV-VPLFHVVFKGI-------G-IALS--NGYMWKKQRKFAHTHLRYFGEGQ---------KLLE
2N9  3261a-----RPY-SPMATRIYSGN-----SAG-LFFS--NGHVWRKQRRFAMATLRSFGLAN---------GSME
2Y2  39b  -----RGP-LPFLLKATN-------GYG-LGIS--NGERWRQLRRFTLSTLRDFGMGR---------KGME
2R1  7138 -----RPS-LPLFKKMTKM------GGL-LNCK--YSKGWIEHRKLACNSFRYFGSGQ---------RLFE
2U1  8899 -----RPD-IPAISIMTKI------SGI-VFAP--YGPLWQKHRRFCLSTLRNFGLGR---------LGLE
2U1       -----RPR-VPLISIVTKE------KGV-VFAH--YGPVWRQQRKFSHSTLRHFGLGK---------LSLE
2Z1  2993a-----RPN-LQLIIDSCH-------GLG-LGFS--SGHLWKQQRQFAISTLRYFGSGS---------KSLE
2K9  12487-----REI-FPIFHDFNK-------GNG-ILFT--NGDQWKEMRRFALMTLKDFGMGK---------RTIE
2K6  Danio-----RDI-SPIFHDFNR-------GYG-IAFS--NGENWREMRRFALSTLRDFGMGR---------KRSE
2Y1  39a  -----RGP-VPFLMKVTR-------GYG-LAIS--NGERWRQLRRFTLTTLRDFGMGR---------KGME
2K10 19693-----RDI-SPIFYDMNQ-------GHG-ILFS--NGETWKEMRRFALSTLRDFGMGK---------RMIE
2K11      -----RDP-IMLVQNANH-------EHG-VLWS--NGESWKEMRRFALTNLRDFGMGK---------KACE
2R1       -----RPC-LPLFMKMTK-------MGG-LLNS-RYGRGWVDHRRLAVNSFRYFGYGQ---------KSFE
2S1       -----RGT-VAMLEGTFD-------GHG-VFFS--NGERWRQLRKFTMLALRDLGMGK---------REGE
2T2P      -----RGS-MAVFERFTR-------GNG-ILFS--NRPCWWTLRNFALGALKKFGLGT---------RTVE
2D6       -----RPP-VPITQILGFGPR----SQG-VFLAR-YGPAWREQRRFSVSTLRNLGLGK---------KSLE
1A1       -----RPD-LYTFTLISN-------GQS-MSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTS--CYLE
1A2       -----RPD-LYTSTLITD-------GQS-LTFSTDSGPVWAARRRLAQNALNTFSIASDPASSSS--CYLE
1B1       -----RPA-FASFRVVSG-------GRS-MAFG-HYSEHWKVQRRAAHSMMRNFFTRQPRSR-----QVLE
1B2  3008a-----RPN-FVSFQNVSG-------GKS-MAFT-SYSKQWRMHRKIAQSTIRAFSSANSQTK-----KVFE
1B3  3008b-----RPN-FVSFQMISG-------GRS-LTFT-NYSKQWKVHRKLAQSSLRAFSSANKQTK-----IAFE
1B1  1553 -----RPD-FTSFKYISN-------GHS-LAFG-TVTDWWKSHRRVAQSTVRMFSTGNLQTK-----KTFE
17        -----RPQ-MATLDIASNN------RKG-IAFA-DSGAHWQLHRRLAMATFALFKDGD---------QKLE
17A1 4175 -----RPR-SVTTDVLSRD------GKD-IAFG-DYSATWRFHRKIVHGALCMFGEGS---------ASIE
17A2 8086 -----RPR-MVTTDLLTRG------GKD-IAFS-DYCPLWKSHRRLVQNSFTLFGEGT---------SRLQ
21        -----RPE-PLTYKLVSKN------YPD-LSLG-DYSLLWKAHKKLTRSALLLGIRDS-----------ME
21   15   -----RAV-SYTADIVSGG------GRN-ISLG-DYTEEWKALRRLVHGALQRCCKHS-----------LH
3A4       -----FTN-RRPFGPVGFM------KSA-ISIA--EDEEWKRLRSLLSPTFTSGKLKE-----------MV
3A5       -----FTN-RRSLGPVGFM------KSA-ISLA--EDEEWKRIRSLLSPTFTSGKLKE-----------MF
3A7       -----FTN-RRPFGPVGFM------KNA-ISIA--EDEEWKRIRSLLSPTFTSGKLKE-----------MV
3A43      -----FTN-QMPLGPMGFL------KSA-LSFA--EDEEWKRIRTLLSPAFTSVKFKE-----------MV
3A47 600  -----FTN-RRNFCLNGDL------YDA-VNIA--EDDDWRRIRNVLSPLFTTGRIKQ---------IFSL
3B1  2213a-----FTN-RR-DSFAGPL------EDS-VSAV--KDERWKRIRSTISPCFTSGRLKN---------AFPI
3B2  2213b-----FTN-HRVRIFSGPL------ETS-VFSA--KDETWKRMRTSISPCFTSGRLRQ---------AFPI
3A48      -----FTN-RRDLGVNGPL------SDA-VSVA--EDEQWKRIRGILSPSFTSGRLKE---------MYTI
3A49      -----FTN-RRDLGLNGPL------RDA-VSVA--EDEQWKRIRGILSPSFTSGRLKE---------MYTI
3A50P     -----FLN-RKSIGPNGIL------STG-LPFL--RDDNWKRVHKIVSPAFSSGRMKD---------MFSI
3A27 trout-----FTN-RRNFHLNGEL------FDA-LSVA--EDDTWRRIRSVLSPSFTSGRLKE---------MFGI
5A1       -----FTN-RMASGLEFKSV-----ADS-VLFL--RDKRWEEVRGALMSAFSPEKLNE-----------MV
5A1  1244 -----FPN-RMSLRFITKPM-----SDC-LLML--RNERWKRVRSILTPAFSASKMKE-----------MV
4A11      -----HGS-YRFLAPWI--------GYG-LLLL--NGQTWFQHRRMLTPAFHYDILKP-----------YV
4A22      -----HGS-YKFLAPRI--------GYG-LLLL--NGQTWFQHRRMLTPAFHNDILKP-----------YV
4A20      -----AVS-HKILESWV--------GRG-LVTL--DGSKWKKHRQIVKPGFNISILKI-----------FI
4B1       -----PDV-YDFFLQWI--------GRG-LLVL--EGPKWLQHRKLLTPGFHYDVLKP-----------YV
4F2       --PKDKFF-YSFLEPWL--------GDG-LLLS--AGDKWSRHRRMLTPAFHFNILKP-----------YM
4F3       --PKDKVF-YSFLKPWL--------GDG-LLLS--AGEKWSRHRRMLTPAFHFNILKP-----------YM
4F8       --DKDIVF-YKTLKPWL--------GDG-LLLS--VGDKWRHHRRLLTPAFHFNILKP-----------YI
4F11      --PKDMIF-YGFLKPWL--------GDG-LLLS--GGDKWSRHRRMLTPAFHFN-LKP-----------YM
4F12      --PKDNLF-IRFLKPWL--------GEG-ILLS--GGDKWSRHRRMLTPAFHFNILKS-----------YI
4F22      --PKDDLF-YGFLKPWL--------GDG-LLLS--KGDKWSRHRRLLTPAFHFDILKP-----------YM
4F28 2425 --VKDELI-YDHLRPWL--------GNS-LLLS--NGEAWSRRRRLLTPAFHFDILKN-----------YV
4X1       -----QYL-QKFSPPLL--------GKG-LAAL--DGPKWFQHRRLLTPGFHFNILKA-----------YI
4V2       -----SSM-YKFLEPWL--------GLG-LLTS--TGNKWRSRRKMLTPTFHFTILED-----------FL
4V5  485  -----SYS-YSFLHPWL--------GTG-LLTS--TGPKWRRRRKMLTPTFHFSILAD-----------FL
4T5  8637 --PKDDLA-YSFIQNWI--------GNG-LLVS--QGQKWFRHRRLLTPGFHYDVLKP-----------YV
4T2seabass--PKDDVS-YRFILSWI--------GEG-LLVS--SGQKWFRHRRFLTPGFHYDVLKP-----------YV
46        -----SKM-YRALQTVFGERLF---GQG-LVSE-CNYERWHKQRRVIDLAFSRSSLVS-----------LM
46   4537 -----KFL-HNRIGSLFGQRFL---GNG-LVTV-RDHEKWYKQRRIMDPAFSSLYLRS-----------LM
20        -----FET-MLKSLLRYQS------GGG-SVSE------NHMRKKLYENGVTDSLKSN-----------FA
20   486  -----FET-MLKSLLGYHS------GGG-GAST------DSIIRKKVYQGAIDTT-KN-------------
26A1      -----VHW-PASVRTIL--------GSG-CLSN-LHDSSHKQRKKVIMRAFSREALEC-----------YV
26A1 12575-----VQW-PASVRTIL--------GSD-TLSN-VHGAQHKTKKKAIMQAFSREALEF-----------YI
26B1 4267 -----VDW-PQSTSTLL--------GPN-SLAN-SIGDIHRKKRKVFAKVFSHEALES-----------YL
26C1 11741-----TQW-PQSTRIIL--------GPN-ALVN-SIGELHKRKRKILAKVFSRKALES-----------YL
26B1      -----TEW-PRSTRMLL--------GPN-TVSN-SIGDIHRNKRKVFSKIFSHEALES-----------YL
26C1      -----SQW-PQSAHILL--------GSH-TLLG-AVGEPHRRRRKVLARVFSRAALER-----------YV
11A1      -----NPE-RFLIPPWVAYHQYYQRPIG-VLLK--KSAAWKKDRVALNQEVMAPEATK-------NFLPLL
11A1 1630 -----YPK-RLKVEAWTSYRDYRNRKYG-VLLK--NGEEWRCNRVLLNKEVISPKVLE-------NFVPLL
11B1      -----HPH-RMSLEPWVAYRQHRGHKCG-VFLL--NGPEWRFNRLRLNPEVLSPNAVQ-------RFLPMV
11B2      -----HPC-RMILEPWVAYRQHRGHKCG-VFLL--NGPEWRFNRLRLNPDVLSPKAVQ-------RFLPMV
11B1 fugu -----HPR-RMTLQPWATHRETRKHGKG-GFHK--NGEEWRADRLLLNKEVMMSEAVR-------RFIPLL
27A1      -----YPV-RNDMELWKEHRDQHDLTYG-PFTT--EGHHWYQLRQALNQRLLKPAEAA-------LYTDAF
27A1 3437 -----FPN-RGDMSIWKEYRDLRGYGYG-PFTE--KDERWYNLRAVLNKRMLRPKDAL------QYGDTIG
27A2 697  -----YPV-RVQLPHWKEYRDLRGQAYG-LHVE--TGPEWSRLRSALKPRMLKLREVV-------ALSPDE
27A3      -----HPV-RTDMPHWRRYRALRNQAHG-PLTE--XXXXXXXIRSILNPRMLKPQHVS-------SYGITI
27B1      -----RPE-RCSFSPWTEHRRCRQRACG-LLTA--EGEEWQRLRSLLAPLLLRPQAAA-------RYAGTL
27B1 470  -----HPM-RSDLSSWKDYRRLRGHHYG-LLTS--EGEEWQSIRSLLGKHMLRPKAVE----------AYD
27C1      -----APQ-RANMESWREYRDLRGRATG-LISA--EGEQWLKMRSVLRQRILKPKDVA---IYSGEV----
27C1 1410 -----APQ-RANMESWHEYRDMRRRSTG-LISA--EGEDWLRMRSVLRQLIMRPRDVA---VFSDDVSEVV
24        ------PQ-RLEIKPWKAYRDYRKEGYG-LLIL--EGEDWQRVRSAFQKKLMKPGEVM-------KLDNKI
24   1804 -----YPQ-RLEIKPWTAYRDMRDEAYG-LLIL--EGKDWQRVRRAFQQKLMKPTEVV-------KLDRKI
19        -----SKL-GLQ--CIGMH------EKG-IIFN-NNPELWKTTRPFFMKALSGPGLVR-----------MV
19ov 7098 -----SKQ-GLS--CIGMN------ERG-IIFN-NNVTEWRKIRGYFTKALTGPAVQN-----------TV
19br 4200 -----SRA-GLE--CIGME------GQG-VIFN-SDVQLWRRARVYFSKALTGPGLQR-----------TV
8A1       -------D-FHAYAIFLMERIF---DVQ------LPHYSPSDEKARMKLTLLHRELQA-----------LT
8A2  5061 -------D-FVKSKNQLLERIF---FLK------LPGLQPAAEREWMEQHFHGFRLSN-----------LS
8A1  4451 -------D-FHSYAKVLMERIF---QLR------LPNHEPAKEKAVMTQHFLGMNLCG-----------LN
8B1       -------D-FGQYAKKLVLKVF---GYR------SVQGDHEMIHSASTKHLRGDGLKD-----------LN
8B1  7782 -------D-FRKFASHLVRRVF---GYS------SIQNDHDILNASSNRHLKGDGLEV-----------MT
8B2  21917-------D-FRKFASHLVRRVF---GYI------ATKADHEMLNASSNRHLKGDGLEV-----------MT
7B1       -----FRV-FSNKLLEKAFSIS-----Q-LQKN--HDMNDELHLCYQF--LQGKSLDI-----------LL
7A1       -----WKK-FHFATSAKAFGHR-----S-IDPM--DGNTTENINDTFIKTLQGHALNS-----------LT
7A1  5172 -----WRK-FHFATSVKAFGHD-----S-FDPR--HGHTTENLHQTFLKTLQGEALPS-----------LI
7C1  16085-----FHS-FSDSMAPVVFGYP-----P-VRSW--KTPSLHEDIQRAFKLLQGDHLCA-----------LT
39A1      -----ELA-VQNIVYRTASIPK-----N-VFLA-LHEKLYIMLKGKMGTVNLHQFTGQ-----------LT
51        -----EDV-YSRLTTPVF-------GKG-VAYDV-PNPVFLEQKKMLKSGLNI-----------AHFKQHV
51   437  -----EDV-YSRLTTPVF-------GKG-VAYDV-PNPIFLEQKKMLKTGLNI-----------AHFKEHV

2C9       DRVQEEARCLVEELRKTKASPCD---------PTFIL-GCAPCNVICSIIF-------HKRF--DYKDQQF
2C19      DRVQEEARCLVEELRKTKASTCD---------PTFIL-GCAPCNVICSIIF-------QKRF--DYKDQQF
2C18      DRVQEEARCLVEELRKTNASPCD---------PTFIL-GCAPCNVICSVIF-------HDRF--DYKDQRF
2C8       DRVQEEAHCLVEELRKTKASPCD---------PTFIL-GCAPCNVICSVVF-------QKRF--DYKDQNF
2E1       SRIQREAHFLLEALRKTQGQPFD---------PTFLI-GCAPCNVIADILF-------RKHF--DYNDEKF
2F1       ERILEEGSFLLADVRKTEGEPFD---------PTFVL-SRSVSNIICSVLF-------GSRF--DYDDERL
2W1       DKILQELKCLSGQLDGYRGRPF----------PLALL-GWAPSNITFALLF-------GRRF--DYRDPVF
2B6       ERIQEEAQCLIEELRKSKGALMD---------PTFLF-QSITANIICSIVF-------GKRF--HYQDQEF
2A6       ERIQEEAGFLIDALRGTGGANID---------PTFFL-SRTVSNVISSIVF-------GDRF--DYKDKEF
2A7       ERIQEESGFLIEAIRSSHGANID---------PTFFL-SRTVSNVISSIVF-------GDRF--DYEDKEF
2A13      ERIQEEAGFLIDALRGTHGANID---------PTFFL-SRTVSNVISSIVF-------GDRF--DYEDKEF
2G1P      ERIQEEASYLLEEFQKTK-----------------------------------------------------
2G2P      ERIQEEASYLLEEFRKTKGAPID---------PIFLL-SRTVSNVISSVVF-------RSRF--DYEDKQF
2M1  troutERVQEEAKMLVKAFGEYRDSVVN---------PKELL-CNCVGNVICSIVF-------GHRF--ENDDPMF
2J2       ERIQEEAQHLTEAIKEENGQPFD---------PHFKI-NNAVSNIICSITF-------GERF--EYQDSWF
2X2   4007DRIHGEIEYIVNTLEKNNGKTLS---------PHLMF-HNAASNIICQVLF-------GTRY--EYDDHFI
2X3       DRILGEMRRVMEFLEQSDGEPIN---------PETLF-HKAASNIIFQVLF-------AKRF--DNEDDSM
2X1catfishNRILGEIEHLVAKLEKYAGSSMY---------PQTLF-HDAASNIIYLVLF-------GTRY--DYGDETL
2V1  DanioFIIMEEYKFLHQSILDTNGLPFN---------PHYII-NNGVSNIICSMVF-------GRRF--EYTDQRF
2Z2  2993bPFITDEFTHCANIFRSYKGKPLP---------PHLIL-NNVVSNIICSLVF-------GHRF--EYGDKNF
2P3  killiRYIQQECQYLNEAFSEQQGKPFN---------GQALI-NNAVSNIICCLVF-------GNRY--EYNDKQY
2P4       PSIQQECHYLAEAFAQHKG----------------------------------------------------
2N2  killiQSVSEEIQHLQEEMEIEKGKPFN---------PSGLF-TNAVSNIICQLVM-------GKRY--DYTDHRF
2N11 3261cQSICEEAQHLLEEMRSHGGKPFD---------PASLF-TRAVSNIICQLVM-------GKRF--EYSDHKF
2N10 3261bQSICEEAQHLLEEMRSHGGKPFN---------PARLF-NNTVSNIICQLVM-------GKRF--EYSDHKF
2N12 3261dNHIQMESKFMCEAFKDEQGKPFD---------PQYTI-TNAVGNIISALVF-------GHRF--EYSDASF
2N9  3261aLSICEESRHLQEAMESQKGEPFD---------PVPLL-NNAVANIICQIVF-------GRRF--DYTDHMF
2Y2  39b  EWIQEESKHLTARIKTLKVKPFD---------PTFLL-GCTVSNVICCMVF-------GERF--SYDDKQF
2R1  7138 RKISEECMFLVDAIDQHKGKAFN---------PKHLV-TNAVSNITNLIIF-------GQRF--TYDDHNF
2U1  8899 PCIVEGLTNIKTELLRLEEESGGAGVD-----PAPVI-SNAVSNVICSLVL-------GHRF--NHDDQEF
2U1       PKIIEEFKYVKAEMQKHGEDPFC---------PFSII-SNAVSNIICSLCF-------GQRF--DYTNSEF
2Z1  2993aPVVLEEFAHCAKQFSEFKGKPFA---------PQLMF-YNIVTNIICSLVF-------GHRF--EYGDKNF
2K9  12487EKIIKECQYLIEAFEQHQGEAFS---------NAQVI-SYATSNIISAIMY-------GRRF--DYKDPTF
2K6  DanioELIIEEIKYVKEEFEKFGGNPFE---------TKLPL-ALAISNIIASIVF-------SVRF--EYSNTKL
2Y1  39a  EWIQEESKHLVTRIKSTEGAPFD---------PTFFL-SCTVSNVICCLVF-------GQRF--SYDDEHF
2K10 19693DKIAEECQyliqkfeeheektfd---------tsrla-nYATSNIISSIVY-------GSRF--DYDDPRF
2K11      NKIIEECSYLMEELKKWKGEPFD---------TTHPI-NYAVSNIICSMVY-------GNRF--EYDDPEF
2R1       SKILEETKFFNDAIETYKGRPFD---------FKQLI-TNAVSNITNLIIF-------GERF--TYEDTDF
2S1       ELIQAEARCLVETFQGTEGRPFD---------PSLLL-AQATSNVVCSLLF-------GLRF--SYEDKEF
2T2P      ARVLEEAACLLDEFQATIGAPFD---------PVRLL-DNAVSNVICSLVF-------GNRY--RYGDPEF
2D6       QWVTEEAACLCAAFANHSGRPFR---------PNGLL-DKAVSNVIASLTC-------GRRF--EYDDPRF
1A1       EHVSKEAEVLISTLQELMAGPGHFN-------PYRYV-VVSVTNVICAICF-------GRRY--DHNHQEL
1A2       EHVSKEAKALISRLQELMAGPGHFD-------PYNQV-VVSVANVIGAMCF-------GQHF--PESSDEM
1B1       GHVLSEARELVALLVRGSADGAFLD-------PRPLT-VVAVANVMSAVCF-------GCRY--SHDDPEF
1B2  3008aQQIVAEATELVEVFLKLGARGQHFN-------PAHEL-TVAAANVICALCF-------GRRY--GHDDQEF
1B3  3008bQHVTAEANELVQAFLRYSTDGRYFD-------PAHEF-TVAAANVMCALCF-------GKRY--GHDDHEF
1B1  1553 RHLTCEVRELLHLFLGKTKELQYFQ-------PMNYL-VVSTANVISAVCF-------GKRY--SYEDEEF
17        KIICQEISTLCDMLATHNGQSID---------ISFPV-FVAVTNVISLICF-------NTSY--KNGDPEL
17A1 4175 KIICAEAASLCSILSEAWTAGLALD-------LSPEL-TRAVTNVICSLCF-------SSSY--RRGDAEF
17A2 8086 DMVLAAVDSLCEELLSME--GRGFD-------PAPAV-TRAVTNVVCMLVF-------SATY--RHGDSEL
21        PVVEQLTQEFCERMRAQPGTPVA---------IEEEF-SLLTCSIICYLTF-------GDKI---KDDNLM
21   15   NVIERQALQLRKVLVDYRGGAVD---------LSEDF-TVAASNVIITLVF-------GKEY--DKSSSEL
3A4       PIIAQYGDVLVRNLRRE-AETGKPVT------LKDVF-GAYSMDVITSTSF-------GVNI--DSLNNPQ
3A5       PIIAQYGDVLVRNLRRE-AEKGKPVT------LKDIF-GAYSMDVITGTSF-------GVNI--DSLNNPQ
3A7       PIIAQYGDVLVRNLRRE-AETGKPVT------LKHVF-GAYSMDVITSTSF-------GVSI--DSLNNPQ
3A43      PIISQCGDMLVRSLRQE-AENSKSINL-----KEDFF-GAYTMDVITGTLF-------GVNL--DSLNNPQ
3A47 600  MKRQSSKLTSSLEPK---AENEEIIS------IKDFF-GAYNMNVATGVLF-------GMEM--E---P--
3B1  2213aVARYADRITKKLEQ----SNLDEPIN------VKEFL-APYSLDAVTSVSF-------SVEA--DSIN---
3B2  2213bIARYADRFIAKLEQ----TKLEDSTD------IKKLF-GPYSLDVIASSSF-------SVDA--DSIN---
3A48      MLQHSKNLLNFLNKKVE-ADEVID--------VKDVF-GPYSMDVVTSTAF-------SVDI--DSIN---
3A49      MLQHSKNLLNFLHKKVE-ADEVID--------VKDVF-GPYSMDVVTSTAF-------SADI--DSIN---
3A50P     MLQHSNILM-----------------------------------------F-------SIDI--ESLN---
3A27 troutMKQHSSTLLSGMKKQAD-KDQTIE--------VKEFF-GPYSMDVVTSTAF-------SVDI--DSLNNPS
5A1       PLISQACDLLLAHLKRY-AESGDAFD------IQRCY-CNYTTDVVASVPF-------GTPV--DSWQAPE
5A1  1244 PLINTATDALIKNLDAF-AESAEAFN------IHKCF-GCFTMDVVASVAF-------GTQV--DSQN---
4A11      GLMADSVRVMLDKWEELLGQDSP-------LEVFQHV-SLMTLDTIMKCAFSHQ----GSIQV-DRNSQSY
4A22      GLMADSVRVMLDKWEELLGQDSP-------LEVFQHV-SLMTLDTIMKSAFSHQ----GSIQV-DRNSQSY
4A20      TMMSESVRMMLNKWEEHIAQNSR-------LELFQHV-SLMTLDSIMKCAFSHQ----GSIQL-DRSSYLK
4B1       AVFTESTRIMLDKWEEKAREGKS-------FDIFCDV-GHMALNTLMKCTFGRG----DTGLG-HRDSSYY
4F2       KIFNESVNIMHAKWQLLASEGSA------CLDMFEHI-SLMTLDSLQKCVFSFD----SHCQE-KPSEYIA
4F3       KIFNESVNIMHAKWQLLASEGSA------RLDMFEHI-SLMTLDSLQKCVFSFD----SHCQE-KPSEYIA
4F8       KIFSKSANIMHAKWQRLAMEGST------CLDVFEHI-SLMTLDSLQKCIFSFD----SNCQE-KPSEYIT
4F11      KIFNKSVNIMHDKWQRLASEGSA------RLDMFEHI-SLMTLDSLQKCVFSFE----SNCQE-KPSEYIA
4F12      TIFNKSANIMLDKWQHLASEGSS------CLDMFEHI-SLMTLDSLQKCIFSFD----SHCQE-RPSEYIA
4F22      KIFNQSADIMHAKWRHLAEGSAV------SLDMFEHI-SLMTLDSLQKCVFSYN----SNCQE-KMSDYIS
4F28 2425 TKFNTSTNTLHDKWHRLLVEGTT------NIEVFEHF-TLMTLDSLLKCAFSYD----SDCQQ-SSSEYAS
4X1       EVMAHSVKMMLDKWEKICSTQDT------SVEVYEHI-NSMSLDIIMKCAFSKE----TNCQT-NSTHDPY
4V2       DIMNEQANILVKKLEKHINQEAF--------NCFFYI-TLCALDIICETAMGKN----IGAQS-NDDSEYV
4V5  485  EVMNEQAEILVEKLDQQAGKGPF--------NCFSYV-TLCALDIICETAMGKK----IYAQS-NSESEYV
4T5  8637 KLMAHSTKTMLDKWESYAKTNKP-------LEVFEYV-SLMTLDTILNCAFSYD----SNCQT-ERKNTYI
4T2seabassKLMSDSTKTMLDKWGSYANSNES-------FELFQHV-SLMTLDSILKCAFSYN----SNCQTESGTNVYI
46        ETFNEKAEQLVEILEAK---------------ADGQT-PVSMQDMLTYTAMDIL----AKAAF-GMETSML
46   4537 GNFNETADKLMDKLSEI---------------ADNKT-TANMLHLVNCVTMEVL----AKVAF-GVDLDLL
20        LLLKLSEELLDKWLSYPE------------TQHVPLS-QHMLGFAMKSVTQMVM----GSTF---EDDQEV
20   486  NFPLLVDELVGKWKSFPE------------DQHTPLC-AHQLVLAMKTITQLAL----GESF---SEDARV
26A1      PVITEEVGSSLEQWLSCGERG---------LLVYPEV-KRLM-FRIAMRILL------GCEP---QLAGDG
26A1 12575PAMQHEVQAAVQEWLAKDSC----------VLVYPEM-KRLM-FRIAMQILL------GFQL---EQIKTD
26B1 4267 PKIQQVIQESLRVWSSNPEP----------INVYRES-QRLS-FTMAVRVLL------GFRV---SEEEMK
26C1 11741PRLQEVIKCEIAKWCAEPGS----------VDVYAAT-RSLT-FRIAIGVLL------GLHL---EEERID
26B1      PKIQLVIQDTLRAWSSHPEA----------INVYQEA-QKLT-FRMAIRVLL------GFSI---PEEDLG
26C1      PRLQGALRHEVRSWCAAGGP----------VSVYDAS-KALT-FRMAARILL------GLRL---DEAQCA
11A1      DAVSRDFVSVLHRRIKKAGSGNYS------GDISDDL-FRFA-FESITNVIF------GERQ---GMLEEV
11A1 1630 DEVGNDFVVRVHKKIARSGQNKWT------TDLSQEL-FKYA-LESVSSVLY------GERL---GLFLDY
11B1      DAVARDFSQALKKKVLQN----ARGSLT--LDVQPSI-FHYT-IEASNLALF------GERL---GLVGHS
11B2      DAVARDFSQALKKKVLQN----ARGSLT--LDVQPSI-FHYT-IEASNLALF------GERL---GLVGHS
11B1 fugu DEVAQDCHMMQTKVEREGRGERGKRSLT--INPSPDL-FRFALEFASCHVLY------GERI---GLFSSS
27A1      NEVIDDFMTRLDQLRAESASGNQV------SDMAQLF-YYFA-LEAICYILF------EKRI---GCLQRS
27A1 3437 GEVVTDFIRRIYFLRQRSPTGDVV------TDLNNEL-YHFS-LEAIASILF------ETRL---GCLEEE
27A2 697  ------------------------------SREVDGD------LLGISAILF------ETRL---GCLGEK
27A3      NDVVTDFLEKLVWLRAKDGGGVMV------NDVAGEL-YKFA-FEGISSVLF------ESRM---GCLNDE
27B1      NNVVCDLVRRLRRQRGRGTGPPAL------VRDVAGE-FYKFGLEGIAAVLL------GSRL---GCLEAQ
27B1 470  QTLNSVVDDLITKLRLRRSSQGL-------VTDIASE-FYRFGLEGVSSVLF------ESRI---GCLDKI
27C1      NQVIADLIKRIYLLRSQAEDGETV------TNVNDLF-FKYS-MEGVATILY------ESRL---GCLENS
27C1 1410 DEVVDDLIKRIVCLRSQSSDGTTI------CNINDLF-FKYA-MEGIAAILY------ECRL---GCLSQK
24        NEVLADFMGRIDELCDERGHV---------EDLYSEL-NKWS-FESICLVLY------EKRF---GLLQKN
24   1804 NEVLEDFVSRIGKTNIG-GKI---------EDLYFEL-NKWS-FESICLVLY------DKRF---GLLQDK
19        TV----------CAESL-KTHLDRLE-------EVTN-ESGYVDVLTLLRRVMLD---TSNT--LFLRIPL
19ov 7098 EV----------CNSST-QAHLDRLE-------DLAQ-----VDVLSLLRCTVVD---ISNR--LFLDIPI
19br 4200 GV----------CVTST-AKHLDCLV-------DMTD-ASGHVDALNLLRAIVVD---ISNR--LFLRVPL
8A1       EAM--YTNLHAVLLGDATEAGS----------GWHEM-GLL-DFSYSFLL----------RA--GYLTLYG
8A2  5061 GTM--KANIESLLLSDVKGGSAS---------GWRQD-GLF-NFCYSLLF----------RA--GYLTLFD
8A1  4451 SSM--SRHMLEVAKAEMPQNQK----------DWKED-GLF-NLSYSLLF----------KV--GYLTLFG
8B1       ETM--LDSLSFVMLTSKGWSLDA--------SCWHED-SLF-RFCYYILF----------TA--GYLSLFG
8B1  7782 QAMMVNLQNLMLHNVDSSSDQVT----------WREE-KLF-AYCYNIVF----------RA--GYLSLYG
8B2  21917QAMMINLQNLMLHNVDSSSDRVT----------WREE-KLF-AYCYNIVF----------RA--GYLSLYG
7B1       ESMMQNLKQVFEPQLL---KTT----------SWDTA-ELY-PFCSSIIF----------EI--TFTTIYG
7A1       ESMMENLQRIMRPPVSSNSKTA----------AWVTE-GMY-SFCYRVMF----------EA--GYLTIFG
7A1  5172 KTMMGHLQDVMLKSDTLRRSKD----------HWEVD-GIF-AFCYKVMF----------ES--GYLTLFG
7C1  16085EGMMGNLMMLLRQDHLGRRPGAGP--------GWKSG-DMY-EFCSRVMF----------EA--TFLTLYG
39A1      EELHEQLENLGTHGTMDLNNLV----------RHLLY-PVT-VNMLFNKS----------LF-STNKKKIK
51        SIIEKETKEYFESW--GESGE---------KNVFEAL-SELIILTASHCLH-------GKEI---------
51   437  KIIEAETREYFQRW--GDSGE---------RDLFEAL-SELIILTASSCLH-------GKEI---------

2C9       LNLMEKLNENIK----------ILSSPWIQI-CNNFSPIIDY----FPGTH-------------------
2C19      LNLMEKLNENIR----------IVSTPWIQI-CNNFPTIIDY----FPGTH-------------------
2C18      LNLMEKFNENLR----------ILSSPWIQV-CNNFPALIDY----LPGSH-------------------
2C8       LTLMKRFNENFR----------ILNSPWIQV-CNNFPLLIDC----FPGTH-------------------
2E1       LRLMYLFNENFH----------LLSTPWLQL-YNNFPSFLHY----LPGSH-------------------
2F1       LTIIRLINDNFQ----------IMSSPWGEL-YDIFPSLLDW----VPGPH-------------------
2W1       VSLLGLIDEVMV----------LLGSPGLQL-FNVHPWLGAL----LQLHR-------------------
2B6       LKMLNLFYQTFS----------LISSVFGQL-FELFSGFLKY----FPGAH-------------------
2A6       LSLLRMMLGIFQ----------FTSTSTGQL-YEMFSSVMKH----LPGPQ-------------------
2A7       LSLLSMMLGIFQ----------FTSTSTGQL-YEMFSSVMKH----LPGPQ-------------------
2A13      LSLLRMMLGRFQ----------FTGTSTGQL-YEMFSSVMKH----LPGPQ-------------------
2G1P      ----------------------------------------------------------------------
2G2P      LNLLRLINESFI----------EMSTPWAQL-YDMYSGIMQY----LPGRH-------------------
2M1  troutQLIQKAVDAYFN----------VLSSPIGAM-YNMFPRIVWC----FPGNH-------------------
2J2       QQLLKLLDEVTY----------LEASKTCQL-YNVFPWIMKF----LPGPH-------------------
2X2   4007REIVRCFTENAK----------ISNGPWAML-YDSIP-LVRY----LPLPF-------------------
2X3       KFFTNFFRETSQ----------IINGPWSLL-YDSFP-AVRY----LPLPF-------------------
2X1catfishKVYVRLYSENAK----------LANGTWSII-YDALP-ILRS----LPLPF-------------------
2V1  DanioLNMLSLISKALK----------LQTSVFIQL-YAAFPRLMDL----LPGPH-------------------
2Z2  2993bKNLIKLFDQSLQ----------IEASVWAEL-YNSFPLLMKH----VPGPH-------------------
2P3  killiQTILQYFNEAVR----------LQGDLSVQI-YNSIPGLMRW----LPGSH-------------------
2P4       ------------------------------V-YNTFPWLLKW----LPGTH-------------------
2N2  killiQMMLRCMSEAVL----------LEGNVWGQL-YMAFPSVMRY----MPGPH-------------------
2N11 3261cQMLLKYLSELLV----------LEGSFWGQL-YQAFPSVMKH----LPGPH-------------------
2N10 3261bQMLLKYLSEVLV----------LEGSFWGQL-YEAFPSVMKH----LPGPH-------------------
2N12 3261dRRILELDNEAVV----------LAGSARTQL-YDSFPSLMKH----LPGPH-------------------
2N9  3261aQRMLHHLTEMAY----------LEGSIWALL-YDSFPALMKH----LPGPH-------------------
2Y2  39b  LELLRVIAEVLR----------FNSSFLGQM-YNVFPWILEH----LPGPQ-------------------
2R1  7138 QHMIELFSENVE----------LAVSGWALL-YNAFPWIEYL----PFGKH-------------------
2U1  8899 RSMLRLMDRGLE----------ICVNSPAVL-INVFPLLYHL----PFGVF-------------------
2U1       KKMLGFMSRGLE----------ICLNSQVLL-VNICPWLYYL----PFGPF-------------------
2Z1  2993aEKLMNSFGRCLQ----------IEASVCAQL-YNSFPRLMGC----LPGPH-------------------
2K9  12487QAMIERDHEVIH----------LTGSPSIQI-YNIFPWLGPF----LKTWR-------------------
2K6  DanioHRMVGRAYENMK----------LTGSPSVQI-YNMFPWLRPI----VANRN-------------------
2Y1  39a  LSLLHIISETIQ----------FGSSASGLM-YNLFPRLMEW----LPGRH-------------------
2K10 19693INMVNRVNEVIR----------LTGSAPIQL-YNIFPGLANW----IKNRQ-------------------
2K11      TSLVDRTNTLIQ----------ISGSPSVLV-YDLFPWIGPL----VNNKK-------------------
2R1       QHMIELFSENVE----------LAASASVFL-YNAFPWIGIL----PFGKH-------------------
2S1       QAVVRAAGGTLL----------GVSSQGGQT-YEMFSWFLRP----LPGPH-------------------
2T2P      LRLLNLFSDNFC----------------IIS-SRWGESLMDW----LPGPH-------------------
2D6       LRLLDLAQEGLK----------EESGFLREV-LNAVPVLLH-----IPALA-------------------
1A1       LSLVNL-NNNFG----------EVVG-SGNP-ADFIPILRY-----LPNPS-------------------
1A2       LSLVKN-THEFV----------ETAS-SGNP-LDFFPILRY-----LPNPA-------------------
1B1       RELLSH-NEEFG----------RTVG-AGSL-VDVMPWLQY-----FPNPVRTV----------------
1B2  3008aRDVLRR-IDKFG----------QTVG-AGSL-VDVMPWLQS-----FPNPVRSM----------------
1B3  3008bRCLLKK-LNKFG----------ETVG-AGSL-VDVMPWLQS-----FPNPVRSL----------------
1B1  1553 QQVVGR-NDQFT----------RTVG-AGSI-VDVMPWLQY-----FPNPVKSI----------------
17        NVIQNY-NEGII----------DNLS-KDSL-VDLVPWLKI-----FPNKT-------------------
17A1 4175 EAMLHY-SQGIV----------DTVA-KDSL-VDIFPCLQI-----FPNAD-------------------
17A2 8086 QEVLRY-NDGIV----------QTIA-GGGL-VDIYPWMKV-----FPNKT-------------------
21        PAYYKCIQEVLK----------TWSH-WSIQIVDVIPFLRF-----FPNPG-------------------
21   15   QQLHRCLNEIVA----------LWGS-TWISALDTFPLLRK-----FPNPVF------------------
3A4       DPFVENTKKLLR----------FDFLDPFFLSI-IFPFL-------IPILE-------------------
3A5       DPFVESTKKFLK----------FGFLDPLFLSIILFPFL-------TPVFE-------------------
3A7       DPFVENTKKLLR----------FNPLDPFVLSIKVFPFL-------TPILE-------------------
3A43      DPFLKNMKKLLK----------LDFLDPFLLLISLFPFL-------TPVFE-------------------
3A47 600  SLPIKHASKLFKFP--------IPLFMIQGASPRCFPIL-------LPLLQ-------------------
3B1       NPNDPLIVNLKKV---------FKFNFVVFFLVAFFPFC----------AR-------------------
3B2       NPDDPFIINIKKV---------LNLNFWLLLIKNVLPFS----------SY-------------------
3A48      NPSDPFVANIKEM---------TQFSFLNPLVVLFPFLV--------PIFK-------------------
3A49      HPSDPFVANIKKM---------VKFNFLNPLLIFVVLFPFT-----QPIFD-------------------
3A50P     NPSSPFLHYLQEV---------SKYNYMNLWRLLGAIFPFL-----TPLMD-------------------
3A27 troutHPSDPFVANIKKMVK-------FNFLNPLLIFVVLFPFT-------QPIFD-------------------
5A1       DPFVKHCKRFFE----------FCIPRPILVLLLSFPSI-------MVPLA-------------------
5A1  1244 NCDDPFVRHAQLFFS-------FNFFRPIMLFFAAFPSL-------AAPLV-------------------
4A11      IQAISDLNNLVFSRV-------RNAFHQNDTIYSLTSA-GRW----THRA--------------------
4A22      IQAISDLNSLVFCCM-------RNAFHENDTIYSLTSA-GRW----THRA--------------------
4A20      --AVFNLSKISNQRM-------NNFLHHNDLVFKFSSQ-GQI----FSKF--------------------
4B1       -LAVSDLTLLMQQRL-------VSFQYHNDFIYWLTPH-GRR----FLRA--------------------
4F2       --AILELSALVSKRH-------HEILLHIDFLYYLTPD-GQR----FRRA--------------------
4F3       --AILELSALVTKRH-------QQILLYIDFLYYLTPD-GQR----FRRA--------------------
4F8       --AIMELSALVVKRN-------NQFFRYKDFLYFLTPC-GRR----FHRA--------------------
4F11      --AILELSAFVEKRN-------QQILLHTDFLYYLTPD-GQR----FRRA--------------------
4F12      --TILELSALVEKRS-------QHILQHMDFLYYLSHD-GRR----FHRA--------------------
4F22      --AIIELSALSVRRQ-------YRLHHYLDFIYYRSAD-GRR----FRQA--------------------
4F28 2425 --AIIELSDLIIERR-------QRILHHWDWIYWRTQQ-GKR----FKKA--------------------
4X1       AKAIFELSKIIFHRL-------YSLLYHSDIIFKLSPQ-GYR----FQKL--------------------
4V2       -RAVYRMSEMIFRRI-------KMPWLWLDLWYLMFKE-GWE----HKKS--------------------
4V5  485  -KCVSKMSDIISRRQ-------RTPWFWPNFAYYSIGD-GRE----HDST--------------------
4T5  8637 -KAVYELSNLINLRF-------RIFPYHNDLIFYLSPH-GFR----YRKA--------------------
4T2seabass-KAVYELSDLINLRL-------RTFPYHSDLIFYLSPH-GYR----YRKA--------------------
46        -LGAQKPLSQAVKLM-------LEGITASRNTLAKFLP-GKR----KQLREVRES---------------
46   4537 -RKSSPFPRAVELCL-------KGMVFSIRDTFFMLNP-KNW----SFIREVRGA---------------
20        -IIRFQKNHGTVWSE-------IGKGFLDGSLDKNMTR-KKQ----YEDA--------------------
20   486  -DAFRKNHDVVIWSE-------IGKGYMDGSLEKSTSR-KGH----YEKGA-------------------
26A1      --SEQQLVEA------------FEEMTRNLFSLPIDVP-FSG----LYRGMKARNL--------------
26A1 12575---EQKLVEA------------FEEMIKNLFSLPIDMP-FSG----LYRG--------------------
26B1 4267 -----HLFST------------FQDFVDNLFSLPIDLP-FSG----YRKG--------------------
26C1 11741-----YLAQI------------FGQLMSNLFSLPIDAP-FSG----LRKG--------------------
26B1      -----HLFEV------------YQQFVDNVFSLPVDLP-FSG----YRRG--------------------
26C1      -----TLART------------FEQLVENLFSLPLDVP-FSG----LRKG--------------------
11A1      VNPEAQRFIDAI----------YQMFHTSVPMLNLPPDLFRL----FR----------------------
11A1 1630 IDPEAQHFIDCI----------SLMFKTTSPMLYIPPALLRK----VG----------------------
11B1      PSSASLNFLHAL----------EVMFKSTVQLMFMPRSLSRW----TS----------------------
11B2      PSSASLNFLHAL----------EVMFKSTVQLMFMPRSLSRW----IS----------------------
11B1 fugu PSLESQKFIWAV----------ERMLATTPPLLYLPHRLLLH----LG----------------------
27A1      IPEDTVTFVRSI----------GLMFQNSLYATFLPKWTRPV----------------------------
27A1 3437 IPTGTQDFINAI----------SQMFSNNFQVFLMPKWSRGV----------------------------
27A2 697  VDPNVQRFISGV----------NDMLSLSDITYLFPRWTRSF----------------------------
27A3      VPEETQKFIYSV----------GEMFRLSAVVVLFPQSVWPY----------------------------
27B1      VPPDTETFIRAV----------GSVFVSTLLTMAMPHWLRHL----V-----------------------
27B1 470  VPEETERFIQCI----------NTMFVMTLLTMAMPSWMHQL----F-----------------------
27C1      IPQLTVEYIEAL-------ELMFSMFKTSMYAGAIPRWLRPF----I-----------------------
27C1 1410 IPQETEDYIDAL-------HLMFSSFKTTMYAGAIPKWLRPV----F-----------------------
24        AGDEAVNFIMAI----------KTMMSTFGRMMVTPVELHKS----LN----------------------
24   1804 VNEEAMNFITAV----------KTMMSTFGLMMVTPVELHKS----LN----------------------
19        DESAIVVKIQGY----------FDAWQALLIKPDIF---FKI----------------------------
19ov 7098 NEKELLLKIHKY----------FDTWQTVLIKPDIY---FKF----------------------------
19br 4200 NEKDLLTKIHNY----------FETWQAVLIKPDIF---FKI----------------------------
8A1       IEALPRTHESQAQDRVH-----SADVFHTFRQLDRL---LPK----LARGSLSV----------------
8A2  5061 SADN------------------VTAIYKEFRKFDKL---LSK----LVRGSLKK----------------
8A1  4451 GEQNNNCSD-------------LASIYEEYKKFDGL---LTK----MARGTLKS----------------
8B1       YTKDKEQDLLQAGELFM-----EFRKFDLLFPRFVY---SLL----WPREWLEV----------------
8B1  7782 QEKAKEKDRAESEALYH-----EFRKYDQLFPRLAY---GVL----PPKKQREA----------------
8B2  21917QEKAKEKDRAESEALYH-----EFRKYDQLFPRLAY---GVL----PPKKRREA----------------
7B1       KVIVCDNNKFI-----------SELRDDFLK-FDDK---FAY----LVSNIP------------------
7A1       RDLTRRDTQKAH----------ILNNLDNFKQFDKV---FPA----LVAGLP------------------
7A1  5172 KELARQAAQKAL----------VLNALENFKEFDKI---FPA----LVAGLP------------------
7C1  16085IPQEGGRHDG------------MDELRKDLFQFDGW---FPW----LVAGVP------------------
39A1      EFHQYFQVYDED----------FEYGSQLPECLLR-----------------------------------
51        RSQLNEKVAQLY----------ADLDGGFSHAAWLLPGW-------LP----------------------
51   437  RSMLDERVAQLY----------ADLDGGFTHAAWLLPGW-------LP----------------------

2C9       ---NKLLKNVAFMKSYILEKVKEHQESMDMNNPQD------FIDCFLM-KMEKEK--HNQPSE----FTIESL
2C19      ---NKLLKNLAFMESDILEKVKEHQESMDINNPQD------FIDCFLI-KMEKEK--QNQQSE----FTIESL
2C18      ---NKIAENFAYIKSYVLERIKEHQESLDMNSARD------FIDCFLI-KMEQEK--HNQQSE----FTVESL
2C8       ---NKVLKNVALTRSYIREKVKEHQASLDVNNPRD------FIDCFLI-KMEQEK--DNQKSE----FNIENL
2E1       ---RKVIKNVAEVKEYVSERVKEHHQSLDPNCPRD------LTDCLLV-EMEKEK--HSAERL----YTMDGI
2F1       ---QRIFQNFKCLRDLIAHSVHDHQASLDPRSPRD------FIQCFLT-KMAEEK--EDPLSH----FHMDTL
2W1       ---PVLRKIEEVRAILRTLLEARRPHVCPGDPVCS------YVDALIQ-QGQGDD--PEGL------FAEANA
2B6       ---RQVYKNLQEINAYIGHSVEKHRETLDPSAPKD------LIDTYLL-HMEKEK--SNAHSE----FSHQNL
2A6       ---QQAFQLLQGLENFIAKKVEHNQRTLDPNSPRD------FIDSFLI-RMQEEE--KNPNTE----FYLKNL
2A7       ---QQAFKLLQGLENFIAKKVEHNQRTLDPNSPQD------FIDSFLI-HMQEEE--KNPNTE----FYLKNL
2A13      ---QQAFKELQGLEDFIAKKVEHNQRTLDPNSPRD------FIDSFLI-RMQEEE--KNPNTE----FYLKNL
2G1P      -------------------------------------------------------------------------
2G2P      ---NLIYYLVEELKDFIASRVKINEASFDPQNPRD------FIDCFLI-KMHQDK--NNPRTE----FNLKNL
2M1  trout---HEMFAIVNKAKVYIQEQAEIRLKTLNISEPQD------FIEAFLV-KMLEEK--DDPNTE----FNNGNM
2J2       ---QTLFSNWKKLKLFVSHMIDKHRKDWNPAETRD------FIDAYLK-EMSKHT--GNPTSS----FHEENL
2X2   4007---KNAFKNVETAENLVKDLFVEHKKTRMSGDPRD------FVDCYFD-ELDKR---GKDRSS----FSENML
2X3       ---KRGFEMFKMSHERYLEMFVETKKTRVPGKPRH------FVDAYMD-ELEKR---GDEAF-----FSEDQL
2X1catfish---KKAFDNYSTLKILTANMINKHRTTRVPGKPRD------LVDCYLD-EIDKK---DNEST-----FSEEQL
2V1  Danio---KELFSCFHQVRAFIKEEVDKHRADWDPSSPRD------FIDCYLT-EIEKMK--DDLEAG----FHDEGL
2Z2  2993b---QTVKKIWNEVKDFVRNELKEHRKNWDPSDPRD------YIDCYLR-EIQAS---GQSDST----FDEENL
2P3  killi---KKIFMILQKLVDFVEIRIKEHRENLDPSSPRD------YIDSFLI-EMGEK---EDKDSG----FELSNL
2P4       ---QTIFSEIKTVINFVDLKIQEHKRNFDPSSLRD------YIDCFLA-EMGEK---EDVESG----FDMKNL
2N2  killi---NKIFSHFSSVEQFLYEEVEQHKKDLDRDNPRD------YIDTFLI-EMENH---KESDLG----FTEANL
2N11 3261c---NKVFSHYNHLKDFMNEEIQNHKKNLNHNNPRD------YIDAFII-EMEKNK---DTNLG----FTETNL
2N10 3261b---NKVFSHFNHLKDFMNEEIQNHKKDLDHNNPRD------YIDAFII-EMEKNK---DTNLG----FTETNL
2N12 3261d---QTVHANYGKITDFLKKEVDKHMEEWNPEDPRD------YVDTYLS-EMEKMN--QDPQGG----FNVETL
2N9  3261a---NGIFSSSSSLQGFIWREIQRHKSDLDPSNPRD------YIDAFLI-EEGNG----NNQLG----FEERNL
2Y2  39b  ---HTMFSHVNFLREFIKKKIQEHKESLDPSSPRD------YIDTFLI-RMEQEK--NLPNTE----FHYENL
2R1  7138 ---QKLFFNAAEVYDFLLRVTKEFSQGRVPHMPRH------YVDAYLD-ELERNA--GDPNSS----FSYENL
2U1  8899 ---RELRQVERDITAFLKRFIANHQETLDPNNPRD------LTDMYLK-EISARREAGDVDSG----FTEDYL
2U1       ---KELRQIEKDITSFLKKIIKDHQESLDRENPQD------FIDMYLL-HMEEER-KNNSNSS----FDEEYL
2Z1  2993a---QTVKRIYQNIRDFIREEMKEHKKGLDPSTPRD------YIDCYLN-KIKKS----GAPHT----FHEENL
2K9  12487---YIMKKVEINIES-TRRIIGEMKETRNPGTCRC------FVDAFLI-HKENQEESDVNAHY----YHEDNL
2K6  Danio---QIVKNLRDTFKQ-NEELINGVMKTLDPFNPRG------IVDSFLI-RQQKDEESGKTDSL----YNSNNL
2Y1  39a  ---REMFGKIEKVRAFTMEKIEEHQDTLDPSSPRD------YIDCFLM-RLQQEKP--QPNTE----FNYDNL
2K10 19693---LLLKQVAMNLRD-MTDLIQQLKDTLNPGVCRG------FVDCFLL-RKQKAVDSGVIDSL----YNEKNL
2K11      ---LFQSLFAANKKQ-NLQLFAAAKEMLNPQMCRS------FVDSFLA-RQQILEKSGTNVH-----FHDENL
2R1       ---QQLFRNAAVVYDFLSRLIEKASVNRKPQLPQH------FVDAYLD-EMDQGK--NDPSST----FSKENL
2S1       ---KQLLHHVSTLAAFTVRQVQQHQGNLDASGPARD-----LVDAFLL-KMAQEE--QNPGTE----FTNKNM
2T2P      ---HRIFRNFSELRV-ISEQIQRHWQMRQPAEPRD------FIDCLTR-WVRHGQ--QDPESH----FQE*TS
2D6       ---GKVLRFQKAFLTQLDELLTEHRMTWDPQPPRD------LTEAFLA-EMEKAK--GNPESS----FNDENL
1A1       --LNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRD------ITDSLIE-HCQEKQLDENANVQ----LSDEKI
1A2       --LQRFKAFNQRFLWFLQKTVQEHYQDFDKNSVRD------ITGALFK-HSKKGP-RASGNL-----IPQEKI
1B1       --FREFEQLNRNFSNFILDKFLRHCESLRPGAPRD------MMDAFIL-SAEKKAAGDSHGGGAR--LDLENV
1B2  3008a--FRSFEALNREFFGFVQLKVEQHRETFDPEVTRD------MSDAIIS-VLEKSD--GETA------LTKDYT
1B3  3008b--YENFKSLNEEFFNFVKNKVQEHRESFDPNVTRD------MSDAMIN-VIEERK--DGT-------LSKEFA
1B1  1553 --FDNFKRLNKEFSDFIRDKVTEHRKSIRPSSVRD------MTDAFIV-SLDKLS--EKTGVP----LWKDYV
17        --LEKLKSHVKIRNDLLNKILENYKEKFRSDSITN------MLDTLMQ-AKMNSDNGNAGPDQDSELLSDNHI
17A1 4175 --LRLLKRCVSVRDKLLQKEYDKHKAAYSDHVQRD------LLDALLR-AKCSAENNNTTGINAESVLTDDHL
17A2 8086 --LSKLKACIAVRDRLLTHKLEEHKATLTDNQPRD------LLDALLM-GQVGRGRRKGSGRVEEDIITEDHV
21        --LRRLKQAIEKRDHIVEMQLRQHKESLVAGQWRD------MMDYMLQ-GVAQPSMEEGSGQ-----LLEGHV
21   15   --SRLLREVSRRDEIIRKHLNQFKCVLCCAQSEGH------RRTDVIT-GSLLEGV-----------LTDMHV
3A4       --VLNICVFPREVTNFLRKSVKRMKESRLEDTQKH------RVD-FLQLMIDSQN-SKETESHKA--LSDLEL
3A5       --ALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKH------RLD-FLQLMIDSQN-SKETESHKA--LSDLEL
3A7       --ALNITVFPRKVISFLTKSVKQIKEGRLKETQKH------RVD-FLQLMIDSQN-SKDSETHKA--LSDLEL
3A43      --ALNIGLFPKDVTHFLKNSIERMKESRLKDKQKH------RVD-FFQQMIDSQN-SKETKSHKA--LSDLEL
3A47 600  --LMGFSLFPRDSFAFVKKIVEKIRAERDGGSHQ-------EFD-FLQHMISTQKNDGIYAVTSG--LTDHEI
3B1  2213a--LFQFLGIDPIPRSSVNYFYNVIKNFKDQHHADT------RGD-FLQVLIQSEIPQSEIKSPKG--LTEHEI
3B2  2213b--LFEFLHIDIIPRSIVDYFFNLIKQLKAQHDQSI------KGD-FLHVMIQNEIPQSEIKSPKG--LTEQEI
3A48      --KMNVSTFPAHVIDFFFNFLRQIKSDRNKDKKKS------RVD-FMQLMVNAQMQEGNEEGSSQKGLTDNEI
3A49      --KVDFSFFPAHVIDFFYNFLRQIKSDRNKDKKKS------RVD-FMQLMVNAQMQEGNEEGSSQKGLTDNEI
3A50P     --KMNITVNSSEALQFFISVIKKIKEERKNNPKD-------RVD-FMQLMLNAQAPDGSNKDCDSAGLSDEEI
3A27 trout--KMKFSFFPTAVTDFFYASLAKIKSGRDTGNSTN------RVD-FLQLMIDSQKGSDGEEQTKG--LTDHEI
5A1       --RILPNKNRDELNGFFNKLIRNVIALRDQQAAEE------RRD-FLQMVLDARHSASPMGVQDFD-LTVDEI
5A1  1244 --GIIPNRRRDFLQLMLDARTSDESVSIEHFDTAH-----PVGEAHNRSEQNQDNQVGPQERPQMKMITEDEI
4A11      --CQLAHQHTDQ--VIQLRKAQLQKEGELEKIKRKR-----HLD-FLDILLL--AKMENGSI-----LSDKDL
4A22      --CQLAHQHTDQ--VIQLRKAQLQKEGELEKIKRKR-----HLD-FLDILLL--AKMENGSI-----LSDKDL
4A20      --NQELHQFTHLEKVIQDRKESLKDKLKQDTTQKR------RWD-FLDILLS--AKVENTKD-----FSEADL
4B1       --CQVAHDHTDQ--VIRERKAALQDEKVRKKIQNRR-----HLD-FLDILLG--ARDEDDIK-----LSDADL
4F2       --CRLVHDFTDA--VIQERRRTLPSQGVDDFLQAKAKSK--TLD-FIDVLLL--SKDEDGKK-----LSDEDI
4F3       --CRLVHDFTDD--VIQERRRTLPSQGVDDFLQAKAKSK--TLD-FIDVLLL--SKDEDGKK-----LSDEDI
4F8       --CRLVHDFTDA--VIQERRRTLTSQGVDDFLQAKAKSK--TLD-FIDVLLL--SEDKNGKE-----LSDEDI
4F11      --CHLVHDFTDA--VIQERRRTLPTQGIDDFLKNKAKSK--TLD-FIDVLLL--SKDEDGKE-----LSDEDI
4F12      --CRLVHDFTDA--VIRERRRTLPTQGIDDFFKDKAKSK--TLD-FIDVLLL--SKDEDGKA-----LSDEDI
4F22      --CDMVHHFTTE--VIQERRRALRQQGAEAWLKAK-QGK--TLD-FIDVLLL--ARDEDGKE-----LSDEDI
4F28 2425 --LSIVHKFTRD--VVQKRLALISQKGVAELAAHR------KRD-FVDIILL--TKDEDGKG-----LTDEEL
4X1       --SRVLNQYTDT--IIQERKKSLQAGVKQDNTPKRK-----YQD-FLDIVLS--AKDESGSS-----FSDIDV
4V2       --LQILHTFTNS--VIAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLS--VTDDEGNR-----LSHEDI
4V5  485  --LKVLHSFTYK--VITERAENVSSVESDSDSDHGR----KKRQAFLDMLLK--TTDEDGNK-----MSHRDI
4T5  8637 --CMVAHSHTEE--VIKKRREALKKEKELERIQAKR-----NLD-FLDILLF--AKDENQQG-----LLDEDI
4T2seabass--IKVAQSHTEE--VIKKRKEALKEEKELDRIQAKK-----NLD-FLNILLL--ARDEKQQG-----LSDEDI
46        --IRFLRQVGRD--WVQRRREALKRGEEV----------------PADILTQ--ILKAEEGA-----QDDEGL
46   4537 --CRLLRQTGAQ--WIQQRKTAMRNGEV-----------------PKDILTQ--IIKSAGKE-----EDEEFM
20        --LMQLESVLRN--IIKERKGRNFSQHI-----------------FIDSLVQ--GN-----------LNDQQI
20   486  --LSEMESTLLS--VVKERKSQRNKSV------------------FVDSLIQ--ST-----------LTERQI
26A1      --IHARIEQNIR--AKICGLRASEAGQG-------------CKD-ALQLLIE--HSWERGER-----LDMQAL
26A1 12575--LKARNFIHAK--IEENIKRKLRESNSDSK----------CRD-ALQQLID--SSKKSGQV-----LSMQVL
26B1 4267 --IRARDTLQKS--IEKAIREKPLCSQGKD-----------YSD-ALDVLME--SAKENGSE-----LTMQEL
26C1 11741--IKARKILHAN--MEKIIEKKMERQQEEEE----------YRD-AFDYMLS--TSKEQGQQ-----ISIQEL
26B1      --IQARQILQKG--LEKAIREKLQCTQGKD-----------YLD-ALDLLIE--SSKEHGKE-----MTMQEL
26C1      --IRARDQLHRH--LEGAISEKLHEDKAAE-----------PGD-ALDLIIH--SARELGHE-----PSMQEL
11A1      --TKTWKDHVAAWDVIFSKADIYTQNFYWELRQKGSVHHD----YRGMLYRL--LGDSK--------MSFEDI
11A1 1630 --AKVWRDHVEAWDGIFNQADRCIQNIYRRLRQETGPSKK----YPGVLASL--LLRDK--------LSIEDI
11B1      --PKVWKEHFEAWDCIFQYGDNCIQKIYQELAF-SRPQQ-----YTSIVAEL--LLNAE--------LSPDAI
11B2      --PKVWKEHFEAWDCIFQYGDNCIQKIYQELAF-NRPQH-----YTGIVAEL--LLKAE--------LSLEAI
11B1 fugu --APLWWDHIFTHAEERIQRGYQRLSHSQSRGP-EGGGR-----YKGVLGQL--MAKGQ--------LSLELI
27A1      --LPFWKRYLDGWNAIFSFGKKLIDEKLEDMEAQLQAAGPD----GIQVSGY--LHFLLASGQ----LSPREA
27A1 3437 --LPYWRRYVAGWDGIFSFATRLIDRKMEFIQQHLDN-------NQNVEGEY--LTYLLSNTQ----MSIKDV
27A2 697  --VPVWKRFAQAWDDISDVASSLIDRRIAEIDARVAN-------GQSVEGLY--LTYLLSSDK----MSRAEI
27A3      --LPLWKKFVAAWDYLFKVAEQMVQKKMEEIQNKVDL-------HQDVEGAY--LTHLLLSEK----MTVTEI
27B1      --PGPWGRLCRDWDQMFAFAQRHVERREAEAAMRNGGQPEK---DLESGAHL--THFLFREE-----LPAQSI
27B1 470  --PKPWNVFCQCWDYMFDFAKGHIDQRMAAEAEKIARG------EEVEGRYL--TYFLSRTS-----LPMKTV
27C1      --PKPWREFCRSWDGLFKFSQIHVDNKLRDIQYQMDRG------RRVSGGLL--TYLFLSQA-----LTLQEI
27C1 1410 --PKPWEEFCDSWDGLFRFS-VHVDKRLKQIESQLQRG------EKVTGGLL--TYMLVAKE-----MSVEEI
24        --TKVWQGHTLAWDTIFKSVKACIDNRLE---------KYS----QQPSADF--LCDIYHQNR----LSKKEL
24   1804 --TKTWQDHTAAWDRIFSTAKVYIDKKLK---------RNS----VIAPDDL--IGDILHQSR----LSKKEL
19        --SWLYKKYEKSVKDLKDAIEVLIAEKRCRISTEEKLEECMD---FATELIL--AEKRGD-------LTRENV
19ov 7098 --GWIHQKHKTAARELQEAIEGLVEQKRRDLEQADKLENIN----FTAELLF--AQNHGE-------LSAENV
19br 4200 --GWLFDKHRRAAQELQDTMAALLKVKRKLVHEAEKLDDVLD---FATELIL--AQEAGE-------FSADNV
8A1       ---GDKDHMCSVKSRLWKLLSPARLARRAHRSKW----LESY---LLHLEEMG--------------VSEEMQ
8A2  5061 ---GETHTVNSSRKRLWELLSADWLSRASGSISW----QQSY---NRFLEKEG--------------VDMEMQ
8A1  4451 ---YEKKTAQSARQRLWELLAPARLAKGSGSTPW----LHAY---RRLLREEG--------------VDNEMQ
8B1       ---GRLQHLFHKMLSVSHSQEKEGISNWLGNMLQ-----------FLREQG----------------VPSAMQ
8B1  7782 ---TKLLEYFWNVLSVQKLKGRDNISRWIWDVQE-----------GKDNAG----------------VKEDMI
8B2  21917---TKLLEYFWNVLSVQKLKGRDNISRWIWDVQE-----------GKDNAG----------------VKEDMI
7B1       --IELLGNVKSIREKIIKCFSSEKLAKMQGWSEV----FQSR---QDVLEKYYV-------------HEDLEI
7A1       --IHMFRTAHNAREKLAESLRHENLQKRESISEL----ISLR---MFLNDTLST-------------FDDLEK
7A1  5172 --IHVFKSAYSARENLAKTMHAEKLSKRENVSDL----ISMR---MILNDSLST-------------FNDVSK
7C1  16085--IGLLRQAKTSRNKLTRSLLPMRISSWSNRSQF----IRRR---QELVEKVDA-------------LKDVDR
39A1      --NWSKSKKWFLELFEKNIPDIKACKSAKDNSMT-----------LLQATL--DIVETE--------TSKENS
51        --LPSFRRRDRAHREIKDIFYKAIQKRRQSQ-EK----IDD----ILQTLL--DATYKDGRP-----LTDDEV
51   437  --LPSFRKRDRAHREIKKIFFKVIEKRRRSG-EN----TDD----ILQTLV--DATYKDGRP-----LSDDEI

2C9       ENTAVDL---FGAGTETTSTTLRYALLLLLKH-PEVTAKVQEEIERVIG----RNR-------SPCMQDRSHM
2C19      VITAADL---LGAGTESTSTTLRYALLLLLKH-PEVTAKVQEEIERVIG----RNR-------SPCMQDRGHM
2C18      IATVTDM---FGAGTETTSTTLRYGLLLLLKY-PEVTAKVQEEIECVVG----RNR-------SPCMQDRSHM
2C8       VGTVADL---FVAGTETTSTTLRYGLLLLLKH-PEVTAKVQEEIDHVIG----RHR-------SPCMQDRSHM
2E1       TVTVADL---FFAGTETTSTTLRYGLLILMKY-PEIEEKLHEEIDRVIG----PSR-------IPAIKDRQEM
2F1       LMTTHNL---LFGGTKTVSTTLHHAFLALMKY-PKVQARVQEEIDLVVG----RAR-------LPALKDRAAM
2W1       VACTLDM---VMAGTETTSATLQWAALLMGRH-PDVQGRVQEELDRVLG----PGR-------TPRLEDQQAL
2B6       NLNTLSL---FFAGTETTSTTLRYGFLLMLKY-PHVAERVYREIEQVIG----PHR-------PPELHDRAKM
2A6       VMTTLNL---FIGGTETVSTTLRYGFLLLMKH-PEVEAKVHEEIDRVIG----KNR-------QPKFEDRAKM
2A7       MMSTLNL---FIAGTETVSTTLRYGFLLLMKH-PEVEAKVHEEIDRVIG----KNR-------QPKFEDRTKM
2A13      VMTTLNL---FFAGTETVSTTLRYGFLLLMKH-PEVEAKVHEEIDRVIG----KNR-------QPKFEDRAKM
2G1P      -------------------------------------AKIHEEINQVIG----PHR-------LPRVDDRVKM
2G2P      VLTTLNL---FFAGTETVSSTLRYGFLLLMKH-PEVEAKIHEEINQVIG----PHR-------LPRVDDRVKM
2M1  troutVMTAWSL---FAAGTETTSSTLRQSFLMMIKY-PHIQESVQKEIDEVIG-----SR-------VPTVDDRVKM
2J2       ICSTLDL---FFAGTETTSTTLRWALLYMALY-PEIQEKVQVEIDRVIG----QGQ-------QPSTAARESM
2X2   4007TMYALDL---HFAGTDTTSNTLLTGFLYLMNY-PHIQERCHQEIDKVLQ----DNE-------TVTYDARNQM
2X3       CAIILDL---HFAGTDTTANTLLSGLLYLMKY-PHIQEYCQQEIDKVMQ----GKN-------EVSFEDRVQM
2X1catfishVVYIMNL---HIAGTDTTSNTLLTSILYLMAH-PDIQKRCQKEIDVVLE----GNS-------QPSFEDRHNM
2V1  DanioQYAVLDL---FVAGTETTSTTLLWAFVYMMKY-QKS-KKVQAEIDKVVG----RYR-------RPSMDDRPCM
2Z2  2993bVICVMDL---FVPGSETTSTTLRWAFLYMAKY-PEIQEKVQAEIDRVVG----QSR-------PLTMDDRVNL
2P3  killiCACTLDL---FGAGTETTTTTLHWGLLYMIYY-PQIQERVQAEIDAVIG----PSR-------QPSVADRENM
2P4       SICTMDL---FGAGTETTTTTLQWGLLYMIYY-PHIQEKVYAEISAVIG----SSR-------EPSITDRDNM
2N2  killiVYCAIDL---FLAGTETTATTLLWALVFLVKY-PEVQEKVQAEIDSVIE----QAR-------LPSMADRSSM
2N11 3261cVLCSLDL---FLAGTQTTATTLLWALVYLINN-PDIQEKVQAEIDQVIG----QTR-------QPTMADRPNL
2N10 3261bAMCSLDL---FIAGTETTATTLLWDLVYLINN-PDIQGKVQAEIDQVIG----QNR-------QPTMADRPNL
2N12 3261dLICILDL---IEAGTESAATTLRWGLVFILNY-PDVQEKVQEEIDRVIG----QSR-------QPAMADRPNM
2N9  3261aVLCCLDL---FLAGSETTSKTLQWGLIYLIRK-PHIQEKVQVEIDRPIG----RTR-------QPTMADRPNL
2Y2  39b  VSTVLNL---FLAGTETTSSTLRYALGVLIKH-PNVQEEMQREIDNVVR----QDQ-------CPKMEDRKSL
2R1  7138 IYSVGEL---IIAGTETTTNTLRWAMLYMALY-PNIQGRVHREIDSVLA----NGR-------MPTLEDKQKM
2U1  8899 FYIIGDL---FIAGTDTTANSVLWVILYMASY-PDIQ-KVQAEIDGVVG----PLR-------TPSLSDKGKL
2U1       FYIIGDL---FIAGTDTTTNSLLWCLLYMSLN-PDVQ-KVHEEIERVIG----ANR-------APSLTDKAQM
2Z1  2993aVICVWDL---FLAGTDTTTSTLHWLFLFMAKY-PEMQEKVQAEIDEVIG----QSR-------RATMDDCVNM
2K9  12487LHCAMNL---FGAGTDTTATTLQWGLLYITKY-PHIQDGVQEELRRVVG-----NR-------QVRVEDRKNL
2K6  DanioYCTVNNL---FGAGTDTTVTTLRWGLLLMAKY-PEIQAKVQDEIERVIG----GRQ--------PVVEDRKNL
2Y1  39a  VSTVLNL---YLAGTETTSSTIRYALNVLIRH-PKIQEKMQEDIDSVIG----QGR-------CPYVEDRKSL
2K10 19693LYSLSNL---FGAGTDTTATTLRWGLLLMAKY-PRIQGQVQQELSMVVG-----NR-------RVCVEDRKNL
2K11      MSTVMNL---FNAGTDTTATTLRWGLLLMAKY-PLIQDQVQEELRRVIG-----SR-------QVQVEDRKSL
2R1       IFSVGEL---IIAGTETTTNVLRWAILFMALY-PNIQGQVQKEIDLIMG----PNG-------KPSWDDKCKM
2S1       LMTVIYL---LFAGTMTVSTTVGYTLLLLMKY-PHVQKWVREELNRELG----AGQ-------APSLGDRTRL
2T2P      VMT-THF---FFGVTETTSTTLCYGLLILLKY-LEVAAKVQ-ELDPVVG----WRP-------APSLDYRVCL
2D6       RIVVADL---FSAGMVTTSTTLAWGLLLMILH-PDVQRRVQQEIDDVIG----QVR-------RPEMGDQAHM
1A1       INIVLDL---FGAGFDTVTTAISWSLMYLVMN-PRVQRKIQEELDTVIG----RSR-------RPRLSDRSHL
1A2       VNLVNDI---FGAGFDTVTTAISWSLMYLVTK-PEIQRKIQKELDTVIG----RER-------RPRLSDRPQL
1B1       PATITDI---FGASQDTLSTALQWLLLLFTRY-PDVQTRVQAELDQVVG----RDR-------LPCMGDQPNL
1B2  3008aEVTMADL---IGAGLDTVSTALHWMLLLLVKH-PELQSKLHQLIDRVVG----RNR-------LPSIEDRSSL
1B3  3008bEATITDL---IGAGQDTVSTVLQWIVLLLVKH-PDKQAKLHELMDKVVG----QDR-------LPTTEDRSSL
1B1  1553 IPTVGDV---FGASQDTLSTALQWIFLVLVRY-PDMQQRLQEEVDLVVG----RQR-------LPCIEDQQQL
17        LTTIGDI---FGAGVETTTSVVKWTLAFLLHN-PQVKKKLYEEIDQNVG----FSR-------TPTISDRNRL
17A1 4175 LMTVGDI---FGAGVETTTTVMKWAITYLIHH-PQIQSRIQEELDSRVG----MDR-------SPQLSDRGSL
17A2 8086 LMTAAEA---FGAGVETTSTTLLWILAYLLHH-PQVQERVQKELDDHVG----SER-------PVRVSDRARL
21        HMAAVDL---LIGGTETTANTLSWAVVFLLHH-PEIQQRLQEELDHELGPGASSSR-------VP-YKDRARL
21   15   HMATVDL---LIGGSETTAAWLNWTVAFLLHR-PEFQTKVYEELCTVL-----EGR-------YPKYSDRQRL
3A4       VAQSIIF---IFAGYETTSSVLSFIMYELATH-PDVQQKLQEEIDAVLP----NKA-------PPTYDTVLQM
3A5       AAQSIIF---IFAGYETTSSVLSFTLYELATH-PDVQQKLQKEIDAVLP----NKA-------PPTYDAVVQM
3A7       MAQSIIF---IFAGYETTSSVLSFIIYELATH-PDVQQKVQKEIDTVLP----NKA-------PPTYDTVLQL
3A43      VAQSIII---IFAAYDTTSTTLPFIMYELATH-PDVQQKLQEEIDAVLP----NKA-------PVTYDALVQM
3A47 600  VSQLTVL---LTGGYETSTLALTLSIYSLATN-PGSMNRLQEEIDATFP----DAA-------PVTYEALMQM
3B1  2213aLSQAFIF---IFGGYETTTTTLTNVLYGLAIN-PDVLQVLHKEIDTNIP----SDA-------PISYEDLMGL
3B2  2213bLSQSVLF---IFGGYDTTTITITYLLYNLAIN-PDVLQILHSEIDSNFP----KDT-------PFSYEDLVGF
3A48      LAQAMIF---IFGGYETTSSSLGFLAYNLATN-PKIQKKLQEEIDKTFP----GKV-------RPNYDDLMQL
3A49      LAQAMIF---IFAGYETTSSSLGFLAYNLATN-PKIQKKLQEEIDKTFP----GKV-------RPNYDDLMQL
3A50P     MVQALIF---ALVGNGNMAYLVAFTAYNLAVH-PQTQTRLQAEIDRTFP----GKV------SPNSYEELLQL
3A27 troutLSQAMIF---IFAGYETSSSTMSFLAYNLATN-HHVMTKLQEEIDTVFP----NKA-------PIQYEALMQM
5A1       VGQAFIF---LIAGYEIITNTLSFATYLLATN-PDCQEKLLREVDVFKEK---HMA-------PEFCSLEEGL
5A1  1244 VGQAFVF---LVAGYETSSNTLAFACYLLAIN-PECQRELQKEVDHFFT----RHE-------SPDYTNVQEL
4A11      RAEVDTF---MFEGHDTTASGISWILYALATH-PKHQERCREEIHSLLG----DGA-------SITWNHLDQM
4A22      RAEVDTF---MFEGHDTTASGISWILYALATH-PKHQERCREEIHGLLG----DGA-------SITWNHLDQM
4A20      QAEVKTF---MFAGHDTTSSAISWILYCLAKY-PEHQQRCRDEIRELLG----DGS-------SITWEHLSQM
4B1       RAEVDTF---MFEGHDTTTSGISWFLYCMALY-PEHQHRCREEVREILG----DQD-------FFQWDDLGKM
4F2       RAEADTF---MFEGHDTTASVSPGSCTTLQST-QNTRSVCRQEVQELLK----DRE-----PKEIEWDDLAHL
4F3       RAEADTF---MFEGHDTTASGLSWVLYHLAKH-PEYQERCRQEVQELLK----DRE-----PKEIEWDDLAQL
4F8       RAEADTF---MFGGHDTTASGLSWVLYNLARH-PEYQERCRQEVQELLK----DRE-----PKEIEWDDLAQL
4F11      RAEADTF---MFEGHDTTASGLSWVLYHLAKH-PEYQEQCRQEVQELLK----DRE-----PIEIEWDDLAQL
4F12      RAEADTF---MFGGHDTTASGLSWVLYNLARH-PEYQERCRQEVQELLK----DRD-----PKEIEWDDLAQL
4F22      RAEADTF---MFEGHDTTSSGISWMLFNLAKY-PEYQEKCREEIQEVMK----GRE-----LEELEWDDLTQL
4F28 2425 QAEANTF---MFAGHDTTASAICWSLYNLAHH-NHYQEQCRQEVMDLME----GRD-----VDEIKWEDLSSL
4X1       HSEVSTF---LLAGHDTLAASISWILYCLALN-PEHQERCREEVRGILG----DGS-------SITWDQLGEM
4V2       REEVDTF---MFEGHDTTAAAINWSLYLLGSN-PEVQKKVDHELDDVKS----DRP--------ATVEDLKKL
4V5  485  QEEVDTF---MFRGHDTTAASMNWVLHLMGSH-PEAQSKVHQELQEVFG----ESN------RPITTEDLKKL
4T5  8637 RAEVDTF---MFEGHDTTASGISFLLYNLACH-PKHQKLCRKEIMQVLH----GKD-------TMDWEDLNKI
4T2seabassRAEVDTF---MFEGHDTTASGISFILYSLACH-PEHQKICRDEIMQVLD----GKD-------TMDWEDLSKI
46        LDNFVTF---FIAGHETSANHLAFTVMELSRQ-PEIVARLQAEVDEVIG----SKR-------YLDFEDLGRL
46   4537 LDNFLTF---FIAGQETTANQLGFCIMELGRH-PDILERVKKEVDEAIG----MKQ-------DISYDDLGHL
20        LEDSMIF---SLASCIITAKLCTWAICFLTTS-EEVQKKLYEEINQVFG----NGP--------VTPEKIEQL
20   486  MEDCMVF---MLAGCAITANVCIWALHFLSTS-EEVQDRLYKEFEEVLG----SSP--------VSLEKIPQL
26A1      KQSSTEL---LFGGHETTASAATSLITYLGLY-PHVLQKVREELKSKGLLCKSNQDN------KLDMEILEQL
26A1 12575KESATEL---LFGGHETTASTATSLIMFLGLN-PEVLDKLRHELSDKVMHKGFLDLR------SLNLETLEQL
26B1 4267 KESTIEL---IFAAFATTASASTSLIMQLLRH-PPVLERLREELRARGLLHNGCLCPEG----ELRLDTIVSL
26C1 11741KETAVEL---IFAAHSTTASAATSLVLQLLHH-PEVVERVRVELEAQKLCTFPQSQCHAS---NLSLDKLNQL
26B1      KDGTLEL---IFAAYATTASASTSLIMQLLKH-PTVLEKLRDELRAHGILHSGGCPCEG----TLRLDTLSGL
26C1      KESAVEL---LFAAFFTTASASTSLVLLLLQH-PAAIAKIREELVAQGLGRACGCAPGCGCEPDLSLAALGRL
11A1      KANVTEM---LAGGVDTTSMTLQWHLYEMARN-LKVQDMLRAEVLAARH-----QAQG-----DMATM-LQLV
11A1 1630 KASITEL---MAGGVDTTSITLLWTLYELARH-PNLQEELRAEVAAART-----ESQ------GDMLEMLKRI
11B1      KANSMEL---TAGSVDTTVFPLLMTLFELARN-PNVQQALRQESLAAAA-----SISE-----HPQKA-TTEL
11B2      KANSMEL---TAGSVDTTAFPLLMTLFELARN-PDVQQILRQESLAAAA-----SISE-----HPQKA-TTEL
11B1 fugu KANITEL---MAGAVDTTAVPLQFALFELGRN-PEVQQRVRQQVQESWA-----QAGG-----DPQKA-LQEA
27A1      MGSLPEL---LMAGVDTTSNTLTWALYHLSKN-PEIQEALHEEVVGVVP-----AGQV------PQHKDFAHM
27A1 3437 YGSVSEL---LLAGVDTTSNTLTWTLHLLSKY-PQCQEILFKEVSTSVP-----ADRA------PSAEEVTRM
27A2 697  STCITDL---LLGGVDTTSNTLSWALYHLAKD-PVAQDRLYDEVNSVCP-----NHHQ------PTTDDLANM
27A3      LGSITEL---LLAGVDTTSNTISWALYQLAQN-PSIQDQLYHEVRSVCP-----GNKM------PDSDDIAQM
27B1      LGNVTEL---LLAGVDTVSNTLSWALYELSRH-PEVQTALHSEITAALS-----PGSS----AYPSATVLSQL
27B1 470  YSNVTEL---LLAGVDTISSTLSWSLYELSRH-QAVQASLREEVLSVLG-----GRRV------PTAADVAQM
27C1      YANVTEM---LLAGVDTTSFTLSWTVYLLARH-PEVQQTVYREIVKNLG-----ERHV------PTAADVPKV
27C1 1410 YANVTEM---LLAGVDTTSFTLSWASYLLARH-PDVQQQIHAEVMRVLG-----SEKV------ATAEDVQHL
24        YAAVTEL---QLAAVETTANSLMWILYNLSRN-PQVQQKLLKEIQSVLP-----ENQR-----PREED-LRNM
24   1804 YAAITEL---QIGGVETTANSMLWAIFNLSRN-PGAQRRLLEEIRTVVP-----PEQ------DPCGEHIKSM
19        NQCILEM---LIAAPDTMSVSLFFMLFLIAKH-PNVEEAIIKEIQTVIG-----ER-------DIKIDDIQKL
19ov 7098 MQCVLEM---VIAAPDTLSVSLFFMLLLLKQN-PDVELQLLQEIDAVVG-----KR-------QLQNGDLQKL
19br 4200 RQCVLEM---VIAAPDTLSISLFFMLMLLKQH-PDVELRIVEELSTV-------SR-------TEGEENIDYQ
8A1       ARALVLQ---LWATQGNMGPAAFWLLLFLLKN-PEALAAVRGELESILWQAEQPVSQTT----TLPQKVLDST
8A2  5061 RRASLLQ---LWTTQCNNGPAAFWLLGFLLTH-PEAMEALKSEIRQFNLQDPAVRHRTS------GSPDSRRT
8A1  4451 TRALLLQ---LWATQGNVGPAAFWMLGYLLTH-PEALTAVKTEMEALQLSPLDSSVV---------------T
8B1       DKFNFMM---LWASQGNTGPTSFWALLYLLKH-PEAIRAVREEATQVLGEARLETKQSFA---FKLGA-LQHT
8B1  7782 TRYMFVL---LWASQGNTGPSSFWLLLFLMKH-PEAMRSVKEEIDKVVRESGQEVKPGGPLV-NLSREMLMKT
8B2  21917TRYMFVL---LWASQGNTGPSSFWLLLFLMKH-PEAMRSVKEEIDKAVRESGQEVKPGGPLV-KMSREMLMKT
7B1       GAHHLGF---LWASVANTIPTMFWAMYYLLRH-PEAMAAVRDEIDRLLQSTGQKKGSGFPI--HLTREQLDSL
7A1       AKTHLVV---LWASQANTIPATFWSLFQMIRN-PEAMKAATEEVKRTLENAGQKVSLEGNPI-CLSQAELNDL
7A1  5172 ARTHVAL---LWASQANTLPATFWSLFYMIRS-PDAIKAAREEAQKVFETFGVKIDPHNPTL-NLTRDVLDNM
7C1  16085AAHHFAM---LWASVANTIPACFWSMYNLVSH-PDALQVVRQQILDELKLSGVQFSTDTDV--TLSRDLLDKL
39A1      PNYGLLL---LWASLSNAVPVAFWTLAYVLSH-PDIHKAIMEGISSVFGKAGKDKI-------KVSEDDLENL
51        AGMLIGL---LLAGQHTSSTTSAWMGFFLARD-KTLQKKCYLEQKTVCGE---NLP-------PLTYDQLKDL
51   437  GGMLIGL---LLAGQHTSSTTSAWMGFFMARD-RRLQERCYAEQKAACGE---DLP-------PLSFDQLKDL

2C9       PYTDAVVHEVQRYIDLLPTSL--PHAVTCDIKFRN--------YLIPKGTTILISLTSVLHDNKE-FPNP
2C19      PYTDAVVHEVQRYIDLIPTSL--PHAVTCDVKFRN--------YLIPKGTTILTSLTSVLHDNKE-FPNP
2C18      PYTDAVVHEIQRYIDLLPTNL--PHAVTCDVKFKN--------YLIPKGTTIITSLTSVLHNDKE-FPNP
2C8       PYTDAVVHEIQRYSDLVPTGV--PHAVTTDTKFRN--------YLIPKGTTIMALLTSVLHDDKE-FPNP
2E1       PYMHAVVHEIQRFITLVPSNL--PHEATRDTIFRG--------YIIPKGTVIVPTLDSVLYDNQE-FPDP
2F1       PYTDAVIHEVQRFADIIPMNL--PHRVTRDTAFRG--------FLIPKGTDVITLLNTVHYDPSQ-FLTP
2W1       PYTSAVLHEVQRFITLLPHV---PRCTAADTQLGG--------FLLPKGTPVIPLLTSVLLDETQ-WQTP
2B6       PYTEAVIYEIQRFSDLLPMGV--PHIVTQHTSFRG--------YIIPKDTEVFLILSTALHDPHY-FEKP
2A6       PYMEAVIHEIQRFGDVIPMSL--ARRVKKDTKFRD--------FFLPKGTEVYPMLGSVLRDPSF-FSNP
2A7       PYMEAVIHEIQRFGDVIPMSL--ARRVKKDTKFRD--------FFLPKGTEVFPMLGSVLRDPSF-FSNP
2A13      PYTEAVIHEIQRFGDMLPMGL--AHRVNKDTKFRD--------FFLPKGTEVFPMLGSELRDPRF-FSNP
2G1P      PYTDVVIHEIQRLVDIVPMGV--PHNIIQDTQFRG--------YLLPKGTDVFPLLGSVLKDPKY-FRYP
2G2P      PYTDAVIHEIQRLVDIVPMGV--PHNLIRDTQFRG--------YLLPKGTDVFPLLGSVLKDPKY-FRYP
2M1  troutPYTDAVIHEVQRYMDLSPTSV--PHKVMRDTEFYN--------YHIPEGTMVLPLLSSVLVDPKL-FKNP
2J2       PYTNAVIHEVQRMGNIIPQNV--PREVTVDTTLAG--------YHLPKGTMILTNLTALHRDPTE-WATP
2X2   4007PYMQAVIHEVQRVANTVPLSV--FHCTTKDTEFMG--------YSIPKGTLIIPHLASVLKEEGQ-WKFP
2X3       PYVQAVIHEIQRTANTVPLSV--FHCTTRDTELMG--------YSIPKGTLIIPNLSSVLNEKGQ-WKSS
2X1catfishPYTQAVVHECQRIARTVPLSV--FHCTTRDTELMG--------YTIPKGTMIIPNLSSVLSEEGQ-WKFP
2V1  DanioPYTDAVIHEIQRMGNVVPLSV--PRMTNEDTLLEG--------Y-IPKGTQIIPNLTSVLFDQTK-WKTQ
2Z2  2993bPYTDAVLHEIQRFGNIVPLSL--PHVTNKAIQLEG--------YNIPKGIMIIPNLTSALFDKNE-WETP
2P3  killiPYTDAVIHEIQRMGNIIPLNL--PRMANKDTTLDK--------YSIPKGTIIIPTLHSVLQDKSI-WETP
2P4       PYTNAVIHEMQRMANIIPLNV--VHMASSDTTIGN--------YTIPKGTIIMPTLNSVLHDESM-WETP
2N2  killiPYTDAVIHEIQRIGNILPLNG--MRVAAKDTTLGG--------YFIPKGTSLMPVLTSVLFDKAE-WACP
2N11 3261cPYTDAVIHEIQRMGNIVPLNA--SRMAAKDTTLGG--------YFIPKGTSLLPILTSVLFDKNE-WETP
2N10 3261bPYTDAVIHEIQRMGNIVPLNG--PRMAAKDTTLGG--------YFIPKGTSLMPILTSVLFDKNE-WETP
2N12 3261dPYTDAVIHEIQRFANVVPAGF--PKMATKDTTVGG--------YFIPKGLAITTMLSSVLFDKNE-WETP
2N9  3261aPYTDAVIHEIQRMGNIVPLNG-PSNGCQGTRPWRG--------YFIPKGTSVMPNLTSVLFDKNE-WETP
2Y2  39b  PFTDAVIHEVQRFLDIVPFGL--PHYALKDITFRG--------YSIPKGTVIIPLLHSVLKG-DQ-WETP
2R1  7138 PYVEAVLHEVLRFCNIVPLGI--FRATSQDANVNG--------YTIPKGTMVITNLYSVHFDEKY-WSDP
2U1  8899 PFTEAAIMEVQRLTTVVPLAI--PHMTS-ETEFMG--------YTIPKGTVVLPNLWSVHRDPTE-WDDP
2U1       PYTEATIMEVQRLTVVVPLAI--PHMTS-ENTLQG--------YTIPKGTLILPNLWSVHRDPAI-WEKP
2Z1  2993aPYTNAVIHESLRMGNVVPLSL--LHATGRDIQLEG--------YTIPKGTTVIANLTSALFDKNE-WETP
2K9  12487PYMEAVIHETQRMANIVPMSL--PHRTS-DT-FQG--------YVIKKGTMVIPLLTSVLYDESQ-WEKP
2K6  DanioPYTDAVIHEIQRFADISPIGA--PRQTTCDVHLNG--------YFIKKGTPVFPLLVSVLRDE-E-WETP
2Y1  39a  PFTDAVLHEIQRYLDMIPFSI--PHYALQDISFRG--------YTIPKDTLIIPLLHSVLKDDKM-WETP
2K10 19693PYVDAVIHEIQRLGNIAPMAV--PHKTARDVEFRG--------YFIEKGTTVFPLLTSVLYDENE-WETP
2K11      PFTDAVIHETQRLANIVPMAL--PHKTSQDVTLQG--------FFIEKGTTVYPLLTSVLYDETE-WEKP
2R1       PYTEAVLHEVLRFCNIVPLGI--FHATSEDAVVRG--------YSIPKGTTVITNLYSVHFDEKY-WRDP
2S1       PYTDAVLHEAQRLLALVPMGI--PRTLMRTTRFRG--------YTLPQGTEVFPLLGSILHEPNI-FKHP
2T2P      PYANAVLLEIQCFISVVPLGL--PRTLTLDTHLHS--------HCLPKGTFVIPLLVTAHRDPTQ-FKDP
2D6       PYTTAVIHEVQRFGDIVPLGM--THMTSRDIEVQG--------FRIPKGTTLITNLSSVLKDEAV-WEKP
1A1       PYMEAFILETFRHSSFVPFTI--PHSTTRDTSLKG--------FYIPKGRCVFVNQWQINHDQKL-WVNP
1A2       PYLEAFILETFRHSSFLPFTI--PHSTTRDTTLNG--------FYIPKKCCVFVNQWQVNHDPEL-WEDP
1B1       PYVLAFLYEAMRFSSFVPVTI--PHATTANTSVLG--------YHIPKDTVVFVNQWSVNHDPVK-WPNP
1B2  3008aAYLDAFIYETMRFTSFVPVTI--PHSTTSDVTIEG--------LRIPKDTVVFINQWSVNQDPLM-WKDP
1B3  3008bAYLDAFIYETMRFTSFVPVTI--PHSTTSDVTIEG--------LRIPKDTVVFINQWSVNHDPLK-WKDP
1B1  1553 PWVMAFIYEVMRFTSFVPLTI--PHSTTTDTTIMG--------YTIPKNTIIFINQWSINHDPTI-WSHP
17        LLLEATIREVLRLRPVAPMLI--PHKANVDSSIGE--------FAVDKGTEVIINLWALHHNEKE-WHQP
17A1 4175 PYLEATIREVLRIRPVAPLFI--PHVALSDTSIGD--------FAVKKGTRVVINLWSLHHDEKE-WENP
17A2 8086 TYLDCVINEGMRIRPVSPVLI--PHTAMTDSRIGG--------HHISRGTRVLVNMWSIHHDSAH-WDKP
21        PLLNATIAEVLRLRPVVPLAL--PHRTTRPSSISG--------YDIPEGTVIIPNLQGAHLDETV-WERP
21   15   PILCSLIHEVLRLRPVAPLAV--PHKAIRDSSIAG--------YFIPRNTIIIPNLFGAHHDPEV-WSDP
3A4       EYLDMVVNETLRLFPIAMRLE--RVCK-KDVEING--------MFIPKGWVVMIPSYALHRDPKY-WTEP
3A5       EYLDMVVNETLRLFPVAIRLE--RTCK-KDVEING--------VFIPKGSMVVIPTYALHHDPKY-WTEP
3A7       EYLDMVVNETLRLFPVAMRLE--RVCK-KDVEING--------MFIPKGVVVMIPSYVLHHDPKY-WTEP
3A43      EYLDMVVNETLRLFPVVSRVT--RVCK-KDIEING--------VFIPKGLAVMVPIYALHHDPKY-WTEP
3A47 600  EYVDCVINECLRLYPPAARLE--RTAK-ETVEISG--------ITIPKNMTVTVPIFALHRDPEH-WPEP
3B1  2213aQYLDQVLNESQRLYPTAPRLE--RACK-KTVQIHG--------LTILEGTIVGIPVHLLHKDPRF-WSSP
3B2  2213bQYLDQVLNESQRLIPTAPALE--RFCK-KTVQIHG--------LTIPEGTVVAVPVHLLHKDPRF-WSSP
3A48      EYLDMVVNESMRVFPILSRLE--RMTK-TSVEING--------FTIPKGTVVAIPVYVLQHDKAY-WPEP
3A49      EYLDMVVNESMRLYPIANRLE--RMTK-TSVEING--------LTIPKGTVVAIPVYALQRDPVL-WPEP
3A50P     KYLDMVVTETSRLYPLGNRIE--RVAK-STVEVSG--------VIIPEGVAVAVPIYTLHRDPTV-WPDP
3A27 troutDYLDCVLNESLRLYPIAPRLE--RVAK-KTVEING--------IVIPKDCIVLVPTWTLHRDPEI-WSDP
5A1       PYLDMVIAETLRMYPPAFRFT--REAA-QDCEVLG--------QRIPAGAVLEMAVGALHHDPEH-WPSP
5A1  1244 KYLDMVISETLRLYPPGFRFA--REIE-RDCVVNG--------QSFPKGATFEIPAGFLHRDPEH-WPDP
4A11      PYTTMCIKEALRLYPPVPGIG--RELSTPVTFPDG--------RSLPKGIMVLLSIYGLHHNPKV-WPNP
4A22      PYTTMCIKEALRLYPPVPGIG--RELSTPVTFPDG--------RSLPKGIMVLLSIYGLHHNPKV-WPNL
4A20      PYTTMCIKECLRLYAPVVNIS--RLLDKPITFPDG--------RSLPAGITVFINIWALHHNPYF-WEDP
4B1       TYLTMCIKESFRLYPPVPQVY--RQLSKPVTFVDG--------RSLPAGSLISMHIYALHRNSAV-WPDP
4F2       PFLTMCMKESLRCIPPVPVIS--RHVTQDIVLPDG--------RVIPKGIICLISVFGTHHNPAV-WPDP
4F3       PFLTMCIKESLRLHPPVPAVS--RCCTQDIVLPDG--------RVIPKGIICLISVFGTHHNPAV-WPDP
4F8       PFLTMCLKESLRLHPPIPTFA--RGCTQDVVLPDS--------RVIPKGNVCNINIFAIHHNPSV-WPDP
4F11      PFLTMCIKESLRLHPPVPVIS--RCCTQDFVLPDG--------RVIPKGIVCLINIIGIHYNPTV-WPDP
4F12      PFLTMCVKESLRLHPPAPFIS--RCCTQDIVLPDG--------RVIPKGITCLIDIIGVHHNPTV-WPDP
4F22      PFTTMCIKESLRQYPPVTLVS--RQCTEDIKLPDG--------RIIPKGIICLVSIYGTHHNPTV-WPDS
4F28 2425 PFTTMCIRESLRLHSPVQAVT--RRYIQDVKLPGE--------RTVPKGAICLVSIYGTHHNPAV-WTNP
4X1       SYTTMCIKETCRLIPAVPSIS--RDLSKPLTFPDG--------CTLPAGITVVLSIWGLHHNPAV-WKNP
4V2       RYLECVIKETLRLFPSVPLFA--RSVSEDYFLTAG--------YRVLKGTEAVIIPYALHRDPRY-FPNP
4V5  485  KYLESVIKEALRLFPSVPFFA--RSLGEDC-HING--------FKVPKGANAVIITYALHRDPRY-FPEP
4T5  8637 PYTTMCIKESLRMHPPVPGIS--RKTTKPITFFDG--------RTLPAESRIGTSVFGIHRNASL-WENP
4T2seabassPYTTMCIKESLRIYPPVPGMS--RKITKPITFCDG--------RTLPEGSYIGTSVFGIHRNGIV-WENP
46        QYLSQVLKESLRLYPPAWGTF--RLLEEET-LIDG--------VRVPGNTPLLFSTYVMGRMDTY-FEDP
46   4537 GYLSQVLKETLRLYPTAPGTS--RDLKEDM-VIGG--------VHVPGGVVCVFSSYGMGRMETF-FKDP
20        RYCQHVLCETVRTAKLTPVSA--QLQD-IEGKIDR--------FIIPRETLVLYALGVVLQDPNT-WPSP
20   486  RYCQQVLNETLRTAKLTPIAA--RLQE-VEGKVDQ--------HLIPKESLVIYALGVILQDSDT-WNAP
26A1      KYIGCVIKETLRLNPPVPGGF--RVAL-KTFELNG--------YQIPKGWNVIYSICDTHDVAEI-FTNK
26A1 12575KYTSCVIKETLRMNPPVPGGF--RVAL-KTFELGG--------YQIPKGWNVIYSICDTHDVAEI-FPNK
26B1 4267 KYLDCVIKEVLRLFTPVSGAY--RTAM-QTFELDG--------VQIPKGWSVMYSIRDTHDTSTV-FKDV
26C1 11741HYIDCVIKEVLRFLPPVSGGY--RTAL-QTFELDG--------YQIPKGWTVMYSIRDTHETAEI-FQNP
26B1      RYLDCVIKEVMRLFTPISGGY--RTVL-QTFELDG--------FQIPKGWSVMYSIRDTHDTAPV-FKDV
26C1      RYVDCVVKEVLRLLPPVSGGY--RTAL-RTFELDG--------YQIPKGWSVMYSIRDTHETAAV-YRSP
11A1      PLLKASIKETLRLHPISVTLQ--RYLV-NDLVLRD--------YMIPAKTLVQVAIYALGREPTF-FFDP
11A1 1630 PLVKGALKETLRLHPVAVSLQ--RYIA-EDIIIQN--------YHIPAGTLVQLGLYAMGRDPKV-FFRP
11B1      PLLRAALKETLRLYPVGLFLE--RVAS-SDLVLQN--------YHIPAGTLVRVFLYSLGRNPAL-FPRP
11B2      PLLRAALKETLRLYPVGLFLE--RVVS-SDLVLQN--------YHIPAGTLVQVFLYSLGRNAAL-FPRP
11B1 fugu PLLKGTIRETLRLYPVGTTVQ--RYPV-KDIVLQN--------YHIPAGTMVQACLYPLGRSAEV-FEDP
27A1      PLLKAVLKETLRLYPVVPTNS--RIIE-KEIEVDG--------FLFPKNTQFVFCHYVVSRDPTA-FSEP
27A1 3437 PYLRAVVKESLRMFPVIPMNG--RILADKDVMIGG--------YQFSKNTAFNFSHYAIGRDEDT-FPEP
27A2 697  PFLKAVIKEVLRLYPVVHQNA--RFISENDVILND--------YWFPKKTQFHLCHYSVCHDETQ-FKHA
27A3      PYLKAVIRETLRLYPVVPGNA--RVTVDKEIVVGG--------YLFPKQTLFHLCHYCVSHDENI-FPNS
27B1      PLLKAVVKEVLRLYPVVPGNS--RVPD-KDIHVGD--------YIIPKNTLVTLCHYATSRDPAQ-FPEP
27B1 470  PLLKATIKEVLRLYPVIPANA--RVITERDIQVGG--------YLIPKNTLITLCHYATSRDPAV-FPRP
27C1      PLVRALLKETLRLFPVLPGNG--RVTQ-EDLVIGG--------YLIPKGTQLALCHYATSYQDEN-FPRA
27C1 1410 PFIRGLVKETLRLFPVLPGNG--RITQ-DDMVLGG--------YFIPKGTQLALCHYSTSLDDEN-FPSS
24        PYLKACLKESMRLTPGVPFTT--RTLD-KATVLGE--------YALPKGTVLMLNTQVLGSSEDN-FEDS
24   1804 PYLKACLKESMRISPSVPFTS--RTLD-KDTVLGD--------YAIPKGTVLMINSHALGSSEDY-FDDG
19        KVMENFIYESMRYQPVVDLVM--RKAL-EDDVIDG--------YPVKKGTNIILNIGRMHR-LEF-FPKP
19ov 7098 RVLETFINECLRFHPVVDFTM--RRSL-SDDVIEG--------YRVPKGTNIILNTGHMHR-TEF-FLRP
19br 4200 KVMESFINESMRFHPVVDFTM--RKAL-EDDTIEG--------IRIRKGTNIILNIGLMHK-TEF-FPKP
8A1       PVLDSVLSESLRLTAAPFIT---REVV-VDLAMPMADGREF--NLRRGDRLLLFPFLSPQRDPEI-YTDP
8A2  5061 PVFDSILSETLRLTAAVLIS---RVVV-GDKVLRMASGQQY--KLRRGDKAILFPFLSPQMDPEI-HLEP
8A1  4451 PVFDSALDEALRLTAAPFIT---REVL-QDKVLHMADGQQY--LLRKGDRVCLFPFISPQMDPEI-HQEP
8B1       PVLDSVVEETLRLRAAPTLL---RLVH-EDYTLKMSSGQEY--LFRHGDILALFPYLSVHMDPDI-HPEP
8B1  7782 PILDSAVEETLRLTAAPLLT---RAVL-QDMTLKMADGQQY--FIRQGDRVALFPYSAIQMDPEI-HPDP
8B2  21917PILDSAVEETLRLTAAPLLT---RAVL-QDMTLKMADGRQY--FIRQGDRVALFPYSAVQMDPEI-HPDP
7B1       ICLESSIFEALRLSSYSTTI---RFVE-EDLTLSSETGDY---CVRKGDLVAIFPP-VLHGDPEI-FEAP
7A1       PVLNSIIKESLRLSSASLNI---RTAK-EDFTLHLEDGS----YNIRKDSIIALYPQLMHLDPEI-YPDP
7A1  5172 PVLDSIIKEAMRLSSASLNI---RVAK-EDFLLHLDNQEA---YRIRKDDVIALYPPMLHYDPEI-FEDP
7C1  16085LYLESSVNESLRLSSASMNI---RVAQ-EDFSLHLKNERS---ANVRKGDIIVLYPQSLHMDPEV-YEDP
39A1      LLIKWCVLETIRLKAPGVIT---RKVV-KPVEILN--------YIIPSGDLLMLSPFWLHRNPKY-FPEP
51        NLLDRCIKETLRLRPPIMIMM--RMAR-TPQTVAG--------YTIPPGHQVCVSPTVNQRLKDS-WVER
51   437  SLLEGCLKETLRLRPPIMTMM--RMAR-SPQTAAG--------YTIPVGHQVCVSPTVNHRLGDA-WEQR

2C9       -EMFDPHHFLDEGG--------------------NFKKSKYFMPFSAGKRICVGEALAGMELFLF-LTSI
2C19      -EMFDPRHFLDEGD--------------------NFKKSNYFMPFSAGKRICVGEGLARMELFLF-LTFI
2C18      -EMFDPGHFLDKSG--------------------NFKKSDYFMPFSAGKRMCMGEGLARMELFLF-LTTI
2C8       -NIFDPGHFLDKNG--------------------NFKKSDYFMPFSAGKRICAGEGLARMELFLF-LTTI
2E1       -EKFKPEHFLNENG--------------------KFKYSDYFKPFSTGKRVCAGEGLARMELFLL-LCAI
2F1       -QEFNPEHFLDANQ--------------------SFKKSPAFMPFSAGRRLCLGELLARMELFLY-LTAI
2W1       -GQFNPGHFLDANG--------------------HFVKREAFLPFSAGRRVCVGERLARTELFLL-FAGL
2B6       -DAFNPDHFLDANG--------------------ALKKTEAFIPFSLGKRICLGEGIARAELFLF-FTTI
2A6       -QDFNPQHFLNEKG--------------------QFKKSDAFVPFSIGKRNCFGEGLARMELFLF-FTTV
2A7       -QDFNPQHFLDDKG--------------------QFKKSDAFVPFSIGKRYCFGEGLARMELFLF-FTTV
2A13      -QDCSPQHFLDEKG--------------------QFKKSDAFVPFSIGKRYCFGEGLARMELFLF-FTTI
2G1P      -DAFYPQHFLDEQG--------------------RFKKNEAFVPFSSGKRICLGEAMARMELFLY-FTST
2G2P      -DAFYPQHFLDEQG--------------------RFKKNEAFVPFSSGKRICLGEAMDRMELFLY-FTST
2M1  trout-DEFDPENFLDENG--------------------VFKKNDGFFAFGVGKRACPGEALARVELFLF-FTSV
2J2       -DTFNPDHFL-ENG--------------------QFKKREAFMPFSIGKRACLGEQLARTELFIF-FTSL
2X2   4007-NEFNPDNFLNDDG--------------------EFVKPEAFMP-STGPRVCLGEGLARMELFLI-IVTL
2X3       -HEFNPENFLNENG--------------------EFVQPEAFMPFSTGPRVCLGEGLARMELFII-LVSL
2X1catfish-HDFNPSNFLNEQG--------------------QFEKPEAFIPFSAGPRVCLGEGLARMELFLF-LVTL
2V1  Danio-HSFDPQNFLNAQG--------------------K-EKPEAFIPFSLGKRSCPGESLARMELFLF-FTSF
2Z2  2993b-CTFNPGHFLDNEG--------------------KFRKRAAFIPFSAGKRLCLGENLARMELFLF-FTSF
2P3  killi-QTFNPQHFLDQDG--------------------QFRKRDAFMPFSTGKRVCLGEQLARMELFLF-FTSL
2P4       -HSFNPQHFLDQDG--------------------KFRKREAFLPFSAGKRVCLGEQLARMELFLF-FTSL
2N2  killi-DTFNPGHFLDDNG--------------------KFVKRDAFLPFSAGKRACIGESLAKMELFLF-LVAL
2N11 3261c-DKFNPGHFLDAEG--------------------KFKKREAFLPFSAGKRVCLGEGLVKMELFLF-FVSL
2N10 3261b-DKFNPGHFLDAEG--------------------KFKKREALLPFSAGKRVCLGEGLAKMELFLF-FVSL
2N12 3261d-DVFNPNHFLDSEG--------------------RFRKRDAFIPFSAGKRVCIGENLAKMELFLF-FTSI
2N9  3261a-DTFNPEHFLDAEG--------------------KFVRREAFLPFSAGRRACLGEGLARMELLLF-FVSL
2Y2  39b  -WAFNPKHFLDQNG--------------------SFKKNSAFLPFSAGKRSCVGESLARMELFIF-LVTL
2R1  7138 -GVFSPQRFLDANG--------------------NFVRREAFLPFSLGRRQCLGEQLARMEMFLF-FTTL
2U1  8899 -DSFDPTRFLDEDG--------------------TLLRKECFIPFGIGRRVCMGAQLAKMELFLT-VTNL
2U1       -EDFYPNRFLDDQG--------------------QLIKKETFIPFGIGKRVCMGEQLAKMELFLM-FVSL
2Z1  2993a-FAFNPGHFLDEEG--------------------RFRKRTAFLPFSAGRRLCLGENLARMMLFLF-FTSF
2K9  12487-HTFNPAHFLDDEG--------------------RFVRRDAFMPFSAGRRMCLGEGLARMELFLF-FASL
2K6  Danio-DSFNPKHFLNKQG--------------------QFVKKDAFMPFGAGRRVCIGESLARMELFLF-FTSL
2Y1  39a  -GSFNPQHFLDGNG--------------------SFKKNPAFLPFSAGKRACVGESLARMEIFLF-VVSL
2K10 19693-HTFNPSHFLDKDG--------------------KFIKRDAFMPFSAGRRLCLGEGLAKMEIFLF-FTSL
2K11      -LNFYPAHFLDKDG--------------------KFVKREAFLPFSAGRRICLGEGLAKMELFIF-FSTL
2R1       -EVFHPERFLDSSG--------------------YFAKKEALVPFSLGRRHCLGEHLARMEMFLF-FTAL
2S1       -EEFNPDRFLDADG--------------------RFRKHEAFLPFSLGKRVCLGEGLAKAEVFLF-FTTI
2T2P      -DCFNPTNFLD-KG--------------------KFQGNDAFMPFAPAKQMCLGTGLAHSGIFLF-LTAT
2D6       -FRFHPEHFLDAQG--------------------HFVKPEAFLPFSAGRRACLGEPLARMELFLF-FTSL
1A1       -SEFLPERFLTPDG------------------AIDKVLSEKVIIFGMGKRKCIGETIARWEVFLF-LAIL
1A2       -SEFRPERFLTADG-----------------TAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLF-LAIL
1B1       -ENFDPARFLDKDG------------------LINKDLTSRVMIFSVGKRRCIGEELSKMQLFLF-ISIL
1B2  3008a-HVFDPSRFMDEEG------------------SLDRDLACNVMIFSAGKRRCIGDQIAKVEVFLF-FAVL
1B3  3008b-HVFDPSRFLNENG------------------DLNKDLTSGVMIFSSGKRRCIGSQIAKVEVFLF-AAIL
1B1  1553 -ETFDPNRFLNPSG------------------SLNKDLTSRMLIFSMGKRRCIGEELSKLHLFLF-TALI
17        -DQFMPERFLNPAG------------------TQLISPSVSYLPFGAGPRSCIGEILARQELFLI-MAWL
17A1 4175 -ERFDPGRFLNSEG------------------TGLVIPSSSYLPFGAGVRVCLGEALAKMELFLF-LSWI
17A2 8086 -DLFNPDRFRDHQG-------------------QRVTP-SCFLPFGAGPRVCVGESLARLELFLF-LSSL
21        -HEFWPDRFLEPGK------------------------NSRALAFGCGARVCLGEPLARLELFVV-LTRL
21   15   -YSFKPERFLEGGG----------------------GSTRALIPFGGGARLCLGETVAKMELFLF-TAYL
3A4       -EKFLPERFSKKNK--------------------DNIDPYTYTPFGSGPRNCIGMRFALMNMKLA-LIRV
3A5       -EEFRPERFSKKK---------------------DSIDPYIYTPFGTGPRNCIGMRFALMNMKLA-LIRV
3A7       -EKFLPERFSKKNK--------------------DNIDPYIYTPFGSGPRNCIGMRFALVNMKLA-LVRV
3A43      -EKFCPERFSKKNK--------------------DSIDLYRYIPFGAGPRNCIGMRFALTNIKLA-VIRA
3A47 600  -EEFKPDRFSKQNK--------------------GRINPYTYLPFGIGPRKCLGMRLALVIVKLA-LVET
3B1  2213a-EEFRPERFSKDST--------------------EEVNPYAFMPFGLGPRNCVGMRYAILVMKML-IVRL
3B2  2213b-EEFRPERFSKDNI--------------------EEVNPYAFMPFGLGPRNCIGMRYAILVMKMI-LVRV
3A48      -EAFKPERFSKENK--------------------DNVDPYAYLPFGAGPRNCIGNRFALVLMKLA-IAEI
3A49      -EAFKPERFSKENK--------------------DNVDPYAYLPFGAGPRNCIGNRFALVLMKLA-IAEI
3A50P     -DSFKPERFSKDNR--------------------DNIDPYGLL----GPRSCTGTRMSMLVVKLT-LVEI
3A27 trout-EEFKPERFSKENK--------------------ESIDPYTYMPFGAGPRNCIGMRFALIMIKLA-MVEI
5A1       -ETFNPERFTAEAR--------------------QQHRPFTYLPFGAGPRSCLGVRLGLLEVKLT-LLHV
5A1  1244 -DKFIPERFTPEAK--------------------ASRHPFVYIPFGAGPRNCVGMRLAQLEMKMA-LVRL
4A11      -EVFDPFRFAPG----------------------SAQHSHAFLPFSGGSRNCIGKQFAMNELKVA-TALT
4A22      -EVFDPSRFAPG----------------------SAQHSHAFLPFSGGSRNCIGKQFAMNQLKVA-RALT
4A20      -QVFNPLRFSRENS--------------------EKIHPYAFIPFSAGPRNCIGQHFAIIECKVA-VALT
4B1       -EVFDSLRFSTENA--------------------SKRHPFAFMPFSAGPRNCIGQQFAMSEMKVV-TAMC
4F2       -EVYDPFRFDPENI--------------------KERSPLAFIPFSAGPRNCIGQTFAMAEMKVV-LALT
4F3       -EVYDPFRFDPKNI--------------------KERSPLAFIPFSAGPRNCIGQAFAMAEMKVV-LGLT
4F8       -EVYDPFRFDPENA--------------------QKRSPMAFIPFSAGPRNCIGQKFAMAEMKVV-LALT
4F11      -EVYDPFRFNQENI--------------------KERSPLAFIPFSAGPRNCIGQAFAMAEMKVV-LALT
4F12      -EVYDPFRFDPENS--------------------KGRSPLAFIPFSAGPRNCIGQAFAMAEMKVV-LALM
4F22      -KVYNPYRFDPDNP--------------------QQRSPLAYVPFSAGPRNCIGQSFAMAELRVV-VALT
4F28 2425 -HDFDPLRFDPKNQ--------------------EGLSSHAFIPFSSGPRNCIGQKFALAELRVV-VALT
4X1       -KVFDPLRFSQENS--------------------DQRHPYAYLPFSAGSRNCIGQEFAMIELKVT-IALI
4V2       -EEFQPERFFPENA--------------------QGRHPYAYVPFSAGPRNCIGQKFAVMEEKTI-LSCI
4V5  485  -EEFRPERFLPENS--------------------VGRPPYAYLPFSAGLRNCIGQRFALIEEKVV-LASI
4T5  8637 -NVFDHWRFLPENV--------------------SKRSPHAFVPFSAGPRNCIGQNFAMNEMKVV-IAMT
4T2seabass-DVFDHWRFLPENV--------------------SKRSPHAFVPFSAGPRNCIGQNFAMNEMKVV-IALT
46        -LTFNPDRFGPG----------------------APKPRFTYFPFSLGHRSCIGQQFAQMEVKVV-MAKL
46   4537 -LKFDPDRFDPD----------------------APKPYYCYFPFSLGPRSCLGQNFAQMEAKVV-MAKL
20        -HKFDPDRFDDE----------------------LVMKTFSSLGFS-GTQECPELRFAYMVTTVL-LSVL
20   486  -YRFDPDRFEEE----------------------SVKKSFHLLGFS-GSQTCPELRFAYTVATVL-LSVL
26A1      -EEFNPDRFIAPHPED--------------------ASRFSFIPFGGGLRSCVGKEFAKILLKIF-TVEL
26A1 12575-EDFQPERFMMKNCGD--------------------SSRFQYIPFGGGSRMCVGKEFAKVLLKIF-LVEV
26B1 4267 -DVFDPDRFSQERGED-------------------KEGRFHYLPFGGGVRSCLGKQLATLFLRIL-AIEL
26C1 11741-ELFDPDRFVTAQVES-------------------RSSRFSYVPFGGGVRSCVGKELAQIILKTL-TIEL
26B1      -NVFDPDRFSQARSED-------------------KDGRFHYLPFGGGVRTCLGKHLAKLFLKVL-AVEL
26C1      -PEGFDPERFGAAREDSRG----------------ASSRFHYIPFGGGARSCLGQELAQAVLQLL-AVEL
11A1      -ENFDPTRWLSKDK---------------------NITYFRNLGFGWGVRQCLGRRIAELEMTIF-LINM
11A1 1630 -EQYQPSRWLRS-----------------------ETHYFKSLGFGFGPRQCLGRRIAEAEMQLF-LIHM
11B1      -ERYNPQRWLDIKG---------------------SGRNFYHVPFGFGMRQCLGRRLAEVEMLLL-LHHV
11B2      -ERYNPQRWLDIRG---------------------SGRNFHHVPFGFGMRQCLGRRLAEAEMLLL-LHHV
11B1 fugu -LRFDPGRWGKSREEGQRG----------------GGTGFRSLAFGFGARQCVGRRIAENEMQLL-LMHI
27A1      -ESFQPHRWLRNSQPATPR----------------IQHPFGSVPFGYGVRACLGRRIAELEMQLL-LARL
27A1 3437 -ATFMPERWLQDSHN--------------------RPNAFGAIAFGFGVRGCVGRRIAELEMYSF-LCHL
27A2 697  -ERFLPERWLRHSAPLSGYY---------------QHHPYSFIPFGVGVRACVGKRVAELEMYFA-LTR-
27A3      -RVFQPERWLRGREEKS------------------KQHPFGSVPFGFGVRACLGRRVAELEMYLL-LSR-
27B1      -NSFRPARWLGEGP---------------------TPHPFASLPFGFGKRSCMGRRLAELELQMA-LAQI
27B1 470  -DEFLPQRWLNKEQ---------------------SHHPYASVPFGVGKRSCIGRRIAELELYLA-VARI
27C1      -KEFRPERWLRKGDLD-------------------RVDNFGSIPFGHGVRSCIGRRIAELEIHLV-VIQL
27C1 1410 -LEFRPDRWIRKHSSD-------------------RLDNFGSIPFGYGIRSCIGKRIAELEMHLA-LIRI
24        -SQFRPERWLQEKE---------------------KINPFAHLPFGVGKRMCIGRRLAELQLHLA-LCWI
24   1804 -KKFKPERWLREHG---------------------TINPFAHVPFGIGKRMCIGRRLAELQMSLF-L-QL
19        -NEFTLENFAK------------------------NVPYRYFQPFGFGPRGCAGKYIAMVMMKAI-LVTL
19ov 7098 -TEFCLQNFEK------------------------NAPRRYFQPFGSGPRACVGKHIAMVMMKSI-LVTL
19br 4200 -REFSLTNFEQK-----------------------TVPSRFFQPFGCGPRSCVGKHIAMVMMKAI-LATL
8A1       -EVFKYNRFLNPDGSEKKDFYKDG-----------KRLKNYNMPWGAGHNHCLGRSYAVNSIKQF-VFLV
8A2  5061 -QSFKYDRFLNIDMSMKDTFYKNE-----------GRLKYYTMPWGAGRHACVGKEFAVATIKQF-VFFI
8A1  4451 -QKYKFNRFLNEDGSVKKDFYKGG-----------RRLKYYSMPWGAGANGCVGKQFAISTMKQY-IYVL
8B1       -TVFKYDRFLNPNGSRKVDFFKTG-----------KKIHHYTMPWGSGVSICPGRFFALSEVKLF-ILLM
8B1  7782 -RSFKYDRFLNPDGSKKTDFYKAG-----------NKVKYYTMPWGSGISMCPGRFFATNELKQF-AFLM
8B2  21917-RSFKYDRFLNPDGSKKTDFYKAG-----------NKVKYYTMPWGSGASMCPGRFFATNELKQF-AFLM
7B1       -EEFRYDRFIED-GKKKTTFFKRG-----------KKLKCYLMPFGTGTSKCPGRFFALMEIKQL-LVIL
7A1       -LTFKYDRYLDENGKTKTTFYCNG-----------LKLKYYYMPFGSGATICPGRLFAIHEIKQF-LILM
7A1  5172 -YEYKFDRFLDENNQEKTTFTRNG-----------RKLRYFYMPFGSGVTKCPGRFFAVYEIKQF-LTLV
7C1  16085-QTFQFDRYVQDSKGGFFKGG--------------QRLKYYLMPFGSGSSMCPGRHFAVNEIKQF-LCLM
39A1      -ELFKPERWEKGKFRRKH-----------------SFLGTASWAFGAGSSQCPGKVFALLEVQMC-IILI
51        -LDFNPDRYLQDNPA--------------------SGEKFAYVPFGAGRHRCIGENFAYVQIKTI-WSTM
51   437  -LEFKPDRYLDDNPA--------------------AGEKFAYIPFGAGRHRCIGENFAYVQIKTI-WSTL

2C9       LQNF-NLKSLVDPKNLDTTPVVNGFASVPPFYQLCFI-PV*--------------------------
2C19      LQNF-NLKSLIDPKDLDTTFVVNGFASVPPFYQLCFI-PV*--------------------------
2C18      LQNF-NLKSQVDPKDIDITPLPMHLVGVPPLYQLCFI-PV*--------------------------
2C8       LQNF-NLKSVDDLKNLNTTAVTKGIVSLPPSYQICFI-PV*--------------------------
2E1       LQHF-NLKPLVDPKDIDLSPIHIGFGCIPPRYKLCVI-PRS*-------------------------
2F1       LQSF-SLQPLGAPEDIDLTPLSSGLGNLPRPFQLCLR-PR*--------------------------
2W1       LQRYRLLPPPGSPASLDTTP-ARAFTMRPRPRALCAV-PRP*-------------------------
2B6       LQNF-SMASPVAPEDIDLTPQECGVGKIPPTYQIRFL-PR*--------------------------
2A6       MQNF-RLKSSQSPKDIDVSPKHVGFATIPRNYTMSFL-PR*--------------------------
2A7       MQNF-RLKSSQSPKDIDVSSKHVGFATIPRNYTMSFL-PR*--------------------------
2A13      MQNF-RFKSPQSPKDIDVSPKHVGFATIPRNYTMSFL-PR*--------------------------
2G1P      LQNF-SLCSLVPLVDIDITPKLSGFGNITPTYELCLV-AR*--------------------------
2G2P      LQNF-SLHSLVPPVDIDITPKLSGFGNIPPTYELCLV-AR*--------------------------
2M1  troutLQRF-TFTGTKPPEEINIEPACSSFGRLPRSYDCYIK-LRTEK*-----------------------
2J2       MQKF-TFRPPNNEKLSLKFRM--GITISPVSHRLCAV-PQV*-------------------------
2X2   4007LHKF-QFIWPEDAGEPDYTPIF-GATQTPKPYRMKIQ-LRK*-------------------------
2X3       LRKF-RFIWPEDAEEPDLTPVF-GVTQTPKPYSLKVQ-VRSRC*-----------------------
2X1catfishLRRF-QFIWPEDAGEPDFTPIF-GLTLTPKPYRMGVK-LRQPAREK*--------------------
2V1  DanioLQSF-SLSAPDETQTSLDFKC--GMTLSPKPFKICFT-PR*--------------------------
2Z2  2993bMQHF-TFSMPAGVK-PDMSFRF-GVTLAPKPYEICAI-PR*--------------------------
2P3  killiLQRF-TFSAPAGEE-PSLEFKL-GATRSPKPYRLCAT-PR*--------------------------
2P4       LQRF-SFSMADGEQPSLDFQLG-GARFPKPYRLRAIL-R*---------------------------
2N2  killiLQKF-TFSVPEGVE-LSTEGIT-GTTRVPHPYKVSAK-IR*--------------------------
2N11 3261cFQKF-SYSVSGGAELSTEGIT--GITRVPHPFEIHTR-PRSF*------------------------
2N10 3261bFQNF-TFFVPGGAELNTEGIT--GTTRVPHPFEILAR-PR*--------------------------
2N12 3261dLQHF-NLSPVPGQMPSLEGIL--GFTYSPQPFRMIVA-PR*--------------------------
2N9  3261aCQRF-HFSTLDRVELSTEGIT--GATRTPYPFKIYAQ-VR*--------------------------
2Y2  39b  LKDF-TFSCIEGPDSISLNPQYSGFANLPRNYEIVAT-PR*--------------------------
2R1  7138 LQRF-HLQFPVGTIPTIAPKL--GMTLQPKPYSICAV-RRHQKSLISVTTPCHK*------------
2U1  8899 LQTF-HFRLPEGAPRPPLQGRF-GLTLAPCPYTVCIN-PR*--------------------------
2U1       MQSF-AFALPEDSKKPLLTGRF-GLTLAPHPFNITIS-RR*--------------------------
2Z1  2993aMQDF-TISFPAGVSP-AMEYHHFGVTLAPHPFDICAV-SR*--------------------------
2K9  12487LQHF-RFKPAGVSDSLDLTPVV-GITLNPLTHKLRAI-SRF*-------------------------
2K6  DanioLQYF-RFTPPGVSEDDLDLTPVVGFTLNPKPHQLCAV-KRS*-------------------------
2Y1  39a  VQHF-TLSCPGGPDSVDLTPEYSSFANVPRKYKIIAT-PRWQ*------------------------
2K10 19693LQQF-RFTPGVGEDELDLTPVVG-FTLSPSPHKLCAI-PRQ*-------------------------
2K11 10791LQHF-RFRPGVSEDHLDLTPRVG-LTLNPSAHKLCAV-SCL*-------------------------
2R1       LQRF-HLHFPHELVPDLKPRL--GMTLQPQPYLICAE-RR*--------------------------
2S1       LQAF-SLESPCPPDTLSLKPTVSGLFNIPPAFQLQVR-PTDLHSTTQTR*-----------------
2T2P      LQRF-CLLPVVRPGTINLTQCT-GLGSVPPDFQLQPV-AC*--------------------------
2D6       LQHF-SFSVPTG-QPRPSHHGVFAFLVSPSPYELCAV-PR*--------------------------
1A1       LQRV-EFSVPLG-VKVDMTPIYGLTMKHACCEHFQMQ-LRS*-------------------------
1A2       LQQL-EFSVPPG-VKVDLTPIYGLTMKHARCEHVQAR-LRFSIN*----------------------
1B1       AHQC-DFRANPN-EPAKMNFSYGLTIKPKSFKVNVTL-RESMELLDSAVQNLQAKETCQ*-------
1B2  3008aLHQC-SFESSAD-EDLTLNCSYGLTLKPLDFSITAKL-RGKLLKSP*--------------------
1B3  3008bLHQC-SFESDPS-DPLTLDCSYGLTLKPLRCFVSAKP-RGKLLGLVSPA*-----------------
1B1  1553 GHQC-HITDDPA-KPTTMDYNYGLTLKPRGFYVALTL-RGDMRLLDEAASRPPAEEPGRGPLADP*-
17        LQRF-DLEVPDD-GQLPSLEGIPKVVFLIDSFKVKIK-VRQAWREAQAEGST*--------------
17A1 4175 LQRF-TLTVPSG-HSLPSLEGKFGVVLQPTKYKVNAT-PRPGWEGKCKACWN*--------------
17A2 8086 LQRM-SFRLPNG-ASPPDLQGRMGVVLQPVPYKVVVT-PRVG*------------------------
21        LQAF-TLLPSGD-ALPSLQPLPHCSVILKMQPFQVRLQPRGMGAHSPGQNQ*---------------
21   15   LRDF-CFVLPDS-EAPLPDLRGVASVVLKIKSFTVIARPRTGP*-----------------------
3A4       LQNF-SFKPCKE-TQIPLKLSLGGLLQ-PEKPVVLKVESRDGTVSGA*-------------------
3A5       LQNF-SFKPCKE-TQIPLKLDTQGLLQ-PEKPIVLKVDSRDGTLSGE*-------------------
3A7       LQNF-SFKPCKE-TQIPLKLRFGGLLL-TEKPIVLKAESRDETVSGA*-------------------
3A43      LQNF-SFKPCKE-TQIPLKLDNLPILQ-PEKPIVLKVHLRDGITSGP*-------------------
3A47 600  LQKY-SFSVCKE-TEIPFKMDPNTFVG-PINPIKLRVVRR*--------------------------
3B1  2213aLQSY-TVETCKD-TMIPLEFDWKS--Q-PLKPIKLSFIPRQK*------------------------
3B2  2213bLQSY-TVETCKD-TMIPLEFDWKL--Q-PTKQIKLRLVPRQK*------------------------
3A48      LQHY-SFVPCKE-TDIPMVLNTEGLVA-PKNPIKLKLKPRAV*------------------------
3A49      LQHY-SFVTCPE-TDIPMVLGNEGFVT-PKNPIKLKLKLRDVSN*----------------------
3A50P     LQHF-SFVACKE-TMIPMVLDDNGFVH-PKTPIMLIPARTPGSCFSACTYVINVLLTVRRLICSLIN
3A27 troutLQSF-TFSVCDE-TEIPLEMDNQGLLM-PKRPIKLRLEARRNTPSNTTATTLKSPTT*---------
5A1       LHKF-RFQACPE-TQVPLQLESKSALG-PKNGVYIKIVSR*--------------------------
5A1  1244 FRRF-NLLACTE-TKVPLELKSSSTLG-PKNGVFVKIERRHWDESQVNSPSED*-------------
4A11      LLRF-ELLP--DPTRIPI-PIARLVLK-SKNGIHLRLRRLPNPCEDKDQL*----------------
4A22      LLRF-ELLP--DPTRIPI-PMARLVLK-SKNGIHLRLRRLPNPCEDKDQL*----------------
4A20      LLRF-KLAP--DHSRPPQ-PVRQVVLK-SKNGIHVFAKKV*--------------------------
4B1       LLRF-EFSL--DPSRLPI-KMPQLVLR-SKNGFHLHLKPLGPGSGK*--------------------
4F2       LLAF-RVLP--DHTEPRRSRSWSCAQR-ADFGCGWSP*-----------------------------
4F3       LLAF-RVLP--DHTEPRR-K-PELVLR-AEGGLWLRVEPLS*-------------------------
4F8       LLRF-RILP--DHREPRR-T-PEIVLR-AEDGLWLRVEPLG*-------------------------
4F11      LLHF-RILP--THIEPRR-K-PELILR-AEGGLWLRVEPLGANSQ*---------------------
4F12      LLHF-RFLP--DHTEPRR-K-LELIMR-AEGGLWLRVEPLNVSLQ*---------------------
4F22      LLRF-RLSV--DRTRKVR---PELILR-TENGLWLKVEPLPPRA*----------------------
4F28 2425 LLRF-RLLP--GNDPKRET--PFEKVR-AEGGLWLQIKPVTQTQ*----------------------
4X1       LLHF-RVTP--DPTRPLT-FPNHFILK-PKNGMYLHLKKL*--------------------------
4V2       LRHF-WIES--NQKREELGLEGQLILR-PSNGIWIKLKRRNADER*---------------------
4V5  485  LRKF-NVEA--CQKREELRPVGELILR-PEKGIWIKLEKRKPLIPPS*-------------------
4T5  8637 LLKY-ELLE--EPTLKPKIIPR-LVLR-SLNGIHIKIKNANQN*-----------------------
4T2seabassLKKY-HLIE--DPNWKPKIIPR-LVLR-SLNGIHIKIKPVDPQV*----------------------
46        LQRL-EFRL--VPGQRF-GLQEQATLK-PLDPVLCTLRPRGWQPAPPPPPC*---------------
46   4537 IQRF-DFTL--LPGQSF-DILDNGTLR-PKSGVLCSLRHRDHKK*----------------------
20        VKRL-HLLS--VEGQVI--ETKYELVT-SSREEAWITVSKRY*------------------------
20   486  VRQL-KLHR--LKDTLM--EVRSELVS-TPRDETWITFNLRN*------------------------
26A1      ARHC-DWQL---LNGPPT-MKTSPTVY-PVDNLPARFTHFHGE*-----------------------
26A1 12575VTKC-HWSL---LNGPPT-MKTGPTVY-PVDNLPTKFNTYVQN*-----------------------
26B1 4267 ASTS-RFELA--TRQFPR-VITVPVVH-PVDGLKVKFYGLDSNQNEIMAKSEELLGAAV*-------
26C1 11741IRTC-KWTLA--TEKFPK-MQTVPIVH-PVNGLHVNFMYKNLHEIDH*-------------------
26B1      ASTS-RFELA--TRTFPR-ITLVPVLH-PVDGLSVKFFGLDSNQNEILPETEAMLSATV*-------
26C1      VRTA-RWELA--TPAFPA-MQTVPIVH-PVDGLRLFFHPLTPSVAGNGLCL*---------------
11A1      LENF-RVEIQ-HLSDVG-TTFNLILM--PEKPISFTFWPFNQEATQQ*-------------------
11A1 1630 LENF-RVEKQ-RHMEVQ-STFELILL--PDKPIILTLKPLSS*------------------------
11B1      LKNF-LVETL-EQEDIK-MVYRFILM--PSTLPLFTFRAIQ*-------------------------
11B2      LKHF-LVETL-TQEDIK-MVYSFILR--PGTSPLLTFRAIN*-------------------------
11B1 fugu LLGF-DLSVP-SSEDIK-TMCTLILM--PETPPKITFTKL*--------------------------
27A1      IQKY-KVVLAPETGELK-SVARIVLV--PNKKVGLQFLQRQ*-------------------------
27A1 3437 MRHF-EIKPDPKMGELK-SVCRTVLI--PDKPVSLRFLDRGSGHAA*--------------------
27A2 697  -------------------------------------------------------------------
27A3      IRRF-EVRPDPNGAEVK-PITRTLLC--PATPINLQFLDRGAQRAPGPAAGASL*------------
27B1      LTHF-EVQPEPGAAPVR-PKTRTVLV--PERSINLQFLDR*--------------------------
27B1 470  LLEF-DIKPDPEGISVK-PMTRTLLV--PENVINLQFTER*--------------------------
27C1      LQHF-EIKTSSQTNAVH-AKTHGLLT--PGGPIHVRFVNRK*-------------------------
27C1 1410 IQKF-HVCVSPLTTDVK-AKTHGLLC--PGAPINLQFIDREI*------------------------
24        VRKY-DIQAT-DNEPVE-MLHSGTLV--PSRELPIAFCQR*--------------------------
24   1804 VRDF-EIVAT-DNEPLD-VIHSGLLV--PNRELPVAFIKR*--------------------------
19        LRRF-HVKTLQGQCVESIQKIHDLSLH-PDETKNMLEMIFTPRNSDRCLEH*---------------
19ov 7098 LSQY-SVCPHEGLTLDCLPQTNNLSQQ-PVEHQEEAQQLSMRFLPRQRGSWQTV*------------
19br 4200 LSRY-TVCPRHGCTLTSIRQTNNLSQQ-PVEDEHSLAMRFIPRTIQSPS*-----------------
8A1       LVHL-DLELINAD--VEIPEFDLSRYGFGLMQPEHDVPVRYRIRP*---------------------
8A2  5061 LTHF-DLETCDPQ--AKLPPVNPSRYGLGMLQPEGELQVRYRLKRSQPET*----------------
8A1  4451 LTNY-DLELCDPC--ALMPGVNASRYGFGMLQPEGDLLVRYRPRQKL*-------------------
8B1       VTHF-DLELVDPD--TPLPHVDPQRWGFGTMQPSHDVRFRYRLHPTE*-------------------
8B1  7782 LLYF-EFELINPD--EEIPEIDYSRYGFGTMQPDRDLQFRYRLRY*---------------------
8B2  21917LLYF-EFELINPD--EEIPEIDYSRYGFGTMQPDRDLQFRYRRRY*---------------------
7B1       LTYF-DLEIIDDK---PIGLNY-SRLLFGIQYPDSDVLFRYKVKS*---------------------
7A1       LSYF-ELELIEGQ--AKCPPLDQSRAGLGILPPLNDIEFKYKFKHL*--------------------
7A1  5172 LTYF-DMELLDPA--IQVPPLDQSRAGLGILQPTYDVDFRYKLKLAY*-------------------
7C1  16085LLYF-NLEL-EPG--QTRATVDSSRAGLGILFPSAKVHFRYRLRCV*--------------------
39A1      LYKY-DCSLLDP-LPKQSYLHLVGVPQPEGQCRIEYKQRI*--------------------------
51        LRLY-EFDLIDG-YFPTV-NYTTMIHTPENPVIRYKRRSK*--------------------------
51   437  LRMY-EFDLVDG-YFPTI-NYTTMIHTPHNPVIRYKRRHE*--------------------------