ࡱ> jli Lbjbjв 2к_к_Crr8Pl}`````$i""``T7``RPM0} ""}rX :  22 Paramecium tetrauralia P450 sequences (A free-living alveolate). >CYP688A1 CYPA MDNIYQFQLIMMLLWVPLILSFPLLWIILYPLCICYFYKFKYGNKVYVLYF PFLGQFKYRMDGLKFQKDVIYFKRNIAYNHPEVELIXTHIFSRPYFIFIKPE NVKQMLYNYANHKKRTDEIFRD IIACKGLVYAEGQEWKDQKREISNFFTFEQLSSKIPVIKTLIQDTLQYKENQRVNIIKQC ARISLRAMQICFFNQMKDEQINGQHLSEEFQDLSRYFLYVNRKYLIRLHMVVQYIS RSFFGIKSLSTMKSYFMTANEKKFLQRVYVVRNYINNLINNHQKGSEKDVFSILLREPLTEEVR EQIIHQYVTFVFAGMDTT SHSAGLSIYMLGKHPQIQQRLREELTKINFDEIDQKLINPLPLLNAFLNE CLRTQTPSDGIIPRLAVKDHYVGQYLIKKDWYVDVGLQPMMTHPQYFHNHLEFNIERWLN QSEPEAFLPLSYGPRNCLGQHLARIEIKLTLIYIIKTYKVILDDQTDLVMDYTFLYAPSD DRLVKFIRI* FN0AA114CH06SP1 FN0AA133DH07SP1 FN0AA179CF11LM1.SCF FN0AA211BA12LP1 FN0AA303AA02SP1 FN0AA309DE05LP1 FN0AA331AE02SP1 FN0AA336BH11LP1 FN0AA372AF05SP1 FN0AC111DB10GGM1.SCF FN0AC28CB05GGM1.SCF FN0AC80BG04RRM1.SCF FN0AD83CD12GGM1.SCF >CYP688A1-like N-term frag 73% only seq of its kind, probably = CYP688A1 poor quality sequence NIYQFQLIIILFFFPLILSFPFLSIILYPLSISYFYKFNYXNKLYILYFPFLXQLKYR FN0AA378BE01SP1 >CYP689A1 CYPE similar to CYP3 MFQFTILEIILYLVLLLVLLILKPLFLMLIM KIKYGKKMHLMYFPLLGRIIEFSRGIKKHNDLLHFEKMIPQQHPGVEIVVSNTFLGLTHV FFKTEHIKFILNNQDLYKKTSKVLFGEKMLYK () GLAFQDGEDWRLARNVLAKSFEFEQLRARIPLIKRLCEEKFSKVPEDEPIDIINISGNIV GEVITQSFFSQSFKDLNGKTFLSELVDVMVGIISQYREAPIRSMSRT FIFGTKDYPNWTISKVEQRLLARLQKVKDILSDSIKERQSMENKPADFLTAYINTI (1) QQNPKLTEEHAIQQYIMLIFAGIDTTSNLFGACCYALSIHPEWQIKLREEVQKQYSTYEQLN SDNINVSNQITNFINECMRMYTPVPYFIEREVKQDHKVGDYFLKKNSEVSLCLFPNNYDS KNYKDPFTFNPDRWNQQGIDPFVFLPFSIGKRNCIGQHMALMELKCLLVYLLMNFEVNS VGEKQVWTFKFVYTIQNEKFIKLKRIGK* 190 FN0AC26CE07RRM1.SCF FN0AA321CC12SP1 FN0AA275CD02LP1 FN0AC144BB09GGM1.SCF FN0AD88BC04GGM1.SCF FN0AC79AD09GGM1.SCF FN0AC140DH06GGM1.SCF FN0AC97DC02RRM1.SCF FN0AA203CH05SP1 FN0AC238BC12GGM1.SCF FN0AC123BF12GGM1.SCF FN0AC103BH08GGM1.SCF FN0AD230CH07GGM1.SCF FN0AA180BB07LM1.SCF FN0AD225CB03RRM1.SCF FN0AD6AB09GGP1 FN0AC5DA09RRM1.SCF >CYP690A1 CYPF + CYPT 86% to CYPB MNLLILSYLGYLILALIAXFVIAPIPKLLYYKIKYGSAVEIYYFPFIGLIGQILIDLVFRSDVFYSQK RLVLKNNKVKLHISNDLKGGVHFTLIDPKLKKLVFFDQESYKKMEGMPFADTFADQGLLF QNGKSWHKSRQMLTKHFTNQDLLVMVETLKQECKKLQLKDGPIDILTVLKQLTSTTITKT FFGSENNEIADLGVQVNKNMEKIMLFLLNPLIVLRCFALKLNKSTTPSFLLS SGEKAFLRELQAQKQRIISEIEQGIKKIKENQTLQDNILTTMCKEIINNNITKEEAVHQYFTLL IAGIDTTSHIVKNFCYALGLHPEVQERLRKEINSHIQ*FDDLRPQQLSE FKLLDNFINEAYRQYTAAPSLFNRIA LKDIQLGEFTILKGQSMDLNMMMSHFDPSIFENPLKFDIDRWNSPVLDPYS FTPFSAGPRNCIGQHLATLELKTLLIFLIMNFNLELNNGKIQLGLSNLYGPTRRDFLVLKNINKQL* FN0AD191AA01RRM1.SCF FN0AA9DG10LP1 FN0AA168CC04LP1 FN0AA14AH02SP1 FN0AA14BF03SP1 FN0AD262DA10RRM1.SCF FN0AA249DB11SP1 FN0AD200BH03GGM1.SCF 3 diifs FN0AA217AC03SM1.SCF 86% to CYPB FN0AD109CE02GGM1.SCF FN0AD161DD10RRM1.SCF FN0AA9DG10SP1 FN0AC1DE07GGM1.SCF >CYP690A2 CYPB A second possible intact P450 of Paramecium 27% identical to CYPA MNLIILSYLGYAILALIAYLVIAPIP KLLYYKIKFGSAVDIYYFPIIGLIGQIIIDLIFRKDAFYSQKRYVLKNNKLKLHISNDLK GGVHFSLVDPKLKKLVFFDQESFKKMEGMPFAD TFMDQGLLFQNGKSWHTSRQMLTKHFT YQDLLVMVETLKQECKKLQLQDGPIDILTLLKQLTSTTITKAFFGSENNDVSDLGVEVN KNMEKMMLFFLNPLIVLRCFALKLNKTTTPSFLLSSGEKAFLRELQAQKQRISSQIDNGI KKIKENQTLQDNILTTMCKEIINNNITKEEAIHQYFTLLIAGIDSTSHVVKNFCYALGLYP EVQERLRKEIQSQVQQFDDLRPQQLSQFKLLDNFINESYRHYTAVPSLFNRVALKDIQLG EFTIQKGQSMDLNMMMSHFDPSIFENPLKFDIDRWNSPLLDPYSFNPFSAGPRNCIGQHL ATLEMKTLLVYLILNYKLELNSGKIILGLANMYGPTRRDFLVLKNINKQL* FN0AA259BE02SP1 FN0AA276AB05LP1 FN0AA63BA02LM1.SCF FN0AA91AG05LP1 FN0AC133DE08RRM1.SCF FN0AC15AF02RRM1.SCF FN0AC170BC07RRM1.SCF FN0AC43AA02GGM1.SCF FN0AC79AD06GGM1.SCF FN0AC95BC11RRM1.SCF FN0AD118BH02GGM1.SCF FN0AD207DE01GGM1.SCF FN0AD237CG08GGM1.SCF >CYP691A1 CYPG 84% to CYPC MIYIILGILALIYFITQPLIVVIYFKIKYGKRVIIQYAPMLGLLRTLSQSRAINGDAFQALSVL IKNNRQADILVTNLLFRPLIVFLKPNYYKIFMQQHEAYTKFPMIVDKRLVSKGMLMEGGAKWKQQ RKLLGAHFEYNKLINLIPMINDVAEKKLSGLPNSIFPAMNLASSITGEVVLRAFFGEDIA KLSLNGQDPSLCVTQLITRFGQLITESRFFQIKRALLEEKVFSLFPRKIEKDLFE LNTVMLDHMKKAIKGRMEKLKNCKDFVHQDYLDVYLDAYLNKNDQMDPPITEDEILQQ SITLYFAGTETTANLVTTACYFLAENPHLQQEIYQEILEILNGESIITAKHLQNLQ KVTGFLMECLRLKPVAPMLISKKALQDVYIMDIFIKK (1?) GWYVNYMVLSNAQNQNYFPNPKQIDITRWKSDGTLKDSTIDPFAFVPFSAGGRNCIGQ YLALIESKIVISKILMKYKLKLNEKLIKTEWIAKITYGLSNQDYITWEAR FN0AA365AD08SP1 FN0AD146BA04GGM1.SCF FN0AD156BA09RRM1.SCF FN0AC120DC02RRM1.SCF FN0AA229DA03LP1 FN0AC116AE02RRM1.SCF FN0AC167AG03GGM1.SCF FN0AD220DC04RRM1.SCF FN0AA46DH08LM1.SCF FN0AA47CA09LM1.SCF FN0AC156AE04GGM1.SCF FN0AA68AG08LM1.SCF >CYP691A2 CYPC MIYIIFGILALSYLITQPLLVVIYFKIRYGKRVIIQYAPMLGLLRTLSQSRAI NGDAFEALSKRIGDNRQADILVTGLLFRPMIVFLKPKYYRIFMQQHQDYTKFP MIVDKRLMTKGMIMEGGAKWLQQRRLLGTHFEYNKLINLIPMINDVAQRKLANLPNEVFP AMNLASSITGEIVLKAFFGEDIAQLSLNGQDPSQCVTQLITRFGQLTTESRFFQIKRALLEEKV FSLFPRKIEQDLYELNTVMLDHMKKAIKNRMEKLKNCKNIEHQDYLDVYLDVYLNK NDSMDPPITEDEILQQSITLYFAGTETTANLVTTACYFLAENQLLQEEIYQEILEVLNGE LIITAKHLQNLQRVAGFLMECLRLKPVAPMLISKQALKDLYIKDIFIKK (1) GWYVNYMVLSNAQDQKYFSNPTQIDITRWKADGTLKDSTIDPFAFVPFSAGGRNCIGQYLAI IESKIVISKILLNYKLXLNQKIAKAEWIAKFTYGLSNQDYITWEAR* FN0AA368AF02SP1 FN0AA278AD11SP1 FN0AD78CC01GGM1.SCF FN0AD108DA12GGM1.SCF FN0AA219CB03LM1.SCF FN0AD193DH08RRM1.SCF FN0AC87CA07RRM1.SCF FN0AD217AH01GGM1.SCF FN0AD22CA02FFP1 FN0AA226AA08SP1 FN0AA211CF03LP1 FN0AD164DE09RRM1.SCF >CYP692A1 CYPW 42% TO CYPR ONLY 27BP BETWEEN GENES CYPR AND CYPW MLLYIFIGLLILFIYFTCLRTYIKLILLK LTLGNKAIIRFYPLTGDFAQIPKSNRIYGDGLKHFQKRVFDNPNVKFVLSNLMHE PLIEIYDPEYYKEVFINHELYQRADVLYHE (2) KFTSRGILYSEGQ RFRQQRQILGNHFTYDKLKERMPKVNQVVIEKIKNQDINQLHQFLVDLTTEIVMRSFFGS EALEFKLNGQSVPAEILELDEEMAAQNLFNPYVVLK RLIFGRKGDKILPSPAQKHLNDRVDRLIDFIISQINKK LSNQQNKGDYFLDIYVDAYLKQEKEFQIEILEICSMFITMFAAGSGT SVALTMTLYFLGLEQEAQQEIRQQIVQV LNGQTEVLDIHLQQLTKLTAFIQEMFRFKAPLFAPFIRKAKKTHYIKNLKIEKGTNVLVL FAAPGWSNKHYDNPEKFDYKRWLNANPIKEDNGFVYMPFSAGMRNCIGQHMAQLNMKIIL SHILMNYKITLDPKQQVRFPINFQIDVEPGNIIQFERIK* FN0AC35DF03RRM1.SCF FN0AD148DA07RRM1.SCF FN0AC14BG01RRM1.SCF FN0AC2AF11RRM1.SCF FN0AA149CC07SP1 FN0AD190BG11RRM1.SCF HAS END OF CYPR and start of CYPW FN0AA172AA12SP1 HAS END OF CYPR and start of CYPW FN0AD55CE11RRM1.SCF >CYP692B1 CYPR 36% to CYPH MICYFCLAGLAI FLYVFVIHIFVKLMLLKLKHGKDVYISFIPLFGDYFFLQQSFKKYGXATEIFKQRCQKNP NIKFVASNILNKIFLFVHDPEYYKQVLVNHENYTKVEILYHP (2) KLSSTSILFGEPQKVKQQRSLLGEAFTFEKLKQRTPIINQVLLEKLQKEDKTNVLDF LTKTSSEIIIKXFFCKELQEIIVQGNDITTEMIDLITQLGDMQMNDLYVSIKLALLGRRS FGLFPSKNEKQLDARIDRLIDGTLMPIIKNKIANYXPNQNSDFLDIYIHAYLNQKPNEPK ITELELCXLFVSIVSAGTDTTSHQIAITLYYLGVERQAQEEIRQEILNVVGNEVDIQPQH LGKLVLLNAFIQEAFRIKNTVIQPLTRIAKETHYIKNLKVEK (1) GTYVAALTTAPSWNDKYFDDPNKFDYKRWLS QRPIKEDNGYVFVPFSAGGRNCIGQHMAMMTMKIMIGQILRQYDVVVDPSVKVTFPLVLF IQYSPQNLVQLKKRKE* FN0AA136DB09LP1 FN0AA248AD09LP1 FN0AA44BC09SM1.SCF FN0AD190BG11RRM1.SCF HAS END OF CYPR and start of CYPW FN0AD210DF06GGM1.SCF FN0AD45BD04GGM1.SCF >CYP692B2P pseudogene of CYPR 50% identical YFKKLSSTSIFFGEPQKVKQQRNLIVKTFGIEKLK (fs) LKSRIPVINQ (fs) VFEKLEQEDKSNVLKFLKKSSEIIIKLK (fs) no fs in FN0AA118AB07LP1 LQYIITTEIMIDLISFCNIVLR MKMNKFYVNIKLAYFGVREFG XXXXXXXXXXXXXXXXXXXX YMDISLDDHSKQQKEFQVLIFKICFIFITMFAAGS SKSDIVLTMALYLLGSEKEAQQEIRKQILLVFNGQTEELE IHLQQLTAFIKEIFRFKAPLFAPFIRAAKKTHY FN0AA118AB07LP1 FN0AA212AG01LP1 FN0AA299DF01SP1 FN0AA333DD12SP1 FN0AA275CB01LP1 FN0AA135BF02LP1 FN0AD230DF10GGM1.SCF FN0AA106CB12LM1.SCF FN0AA106DB02LM1.SCF >CYP693A1 CYPP 60% TO CYPD MLNWILLLISVVAVYLLVNPLVTMMKLKMQFG NAVYCKYFPIFGIIQVYRKSFKLTGNVHQWIMDIVAKHPEVKFVVANSINKPVIFIIDPE YYKQIYLDHHLVTKHDQSGIKD (2) FLLSGGLLFTEGPKWKQQRNLVGDHFLFQKLKARIPMINQVV KEKINGMPVAEKMFEFICTITGEVVIRSFFGVEAEGWKINGKEA QIELGSIFAAFIKLRVTNFFVYFKQKILGVKSWQYXFKKEKEIMDRVTKIKQDIREVIFK RRDKIKQQGNYQGSGDFLDVYLKIFMEQNVYSSDRIETDEIVSQFITLFLAGTDTTGALV ANSLLFISENKQYLQELRNEVNNVIGNGEITPENINQLVFVESFLKEVMRLKP SVVYPIARKAKQNLQIKDLHIKEGTILLLGNFLANLNSQNYDNPLEFNPRRWLQQ QPIKQDNGFINIPFAAGGRNCIGQHMAMIEARIILAYLIRNYDIVRNPQVPKVQWPSRGT QTYIPDNAVHLVKI* FN0AA148AF10LP1 FN0AA163BH04LP1 FN0AA208DA02LM1.SCF FN0AA213AH11LP1 FN0AA299BG12SP1 FN0AA35DF05SP1 FN0AA370CH11LP1 FN0AA49CH09LM1.SCF FN0AC101AH03RRM1.SCF FN0AC122AC07RRM1.SCF FN0AC243AD01GGM1.SCF FN0AC81CD11RRM1.SCF FN0AD153AA03GGM1.SCF FN0AD160AB12GGM1.SCF FN0AD167BG09GGM1.SCF FN0AD97AC04GGM1.SCF >CYP693A2 CYPD + CYPS 59% TO CYPP MIYKLMFLYFFLFLALIGTYLILRPLLIMIKLKVQFGKQVYF YYIPILGVIQIYRSSAKKGNPQQWVIDIITKHPEVKLIVSNSVTKPVFIIVDPEYYKPLY LDHHLLVKHDQSGIKEYIVILNISFLLSKGLLFAEGEKWKEQRSLLGDHFLFEKLKERIP MMNQVTRDAINNKQTVDQVFQYICSITGGVVIRSFFGQEAEGWLINDKPAQIELGEILKS FVLVRFSNFFIYFQIK LLGMKSWDYCLKAEKEILTRVIKFKQDLNQIISKRKSKIEKEGRKWENGDFLDVYLNKLS KSKDTQESYQYETEDIISQFITLFLAGTETTGALVSNSLLFLSENTSYLEELRNEAKSALVD GQVTADSLKKLVQLECFLKEVMRLKPSVVHPIVRQPKSDIQIKDLFIKKGSYILLGSFLA NINSNHYEKPLEFNPKRWLQSKPIQIDNGFVNIPFAAGGRNCIGQHMAMIEARIILAHVI LNYDVIKNPELTKVNWLSRGIQTYLPDDAIRLKKLE* FN0AA250BA01LP1 FN0AA375CB03LP1 FN0AC149CD12RRM1.SCF FN0AD131DA09GGM1.SCF FN0AD171AF02RRM1.SCF FN0AA82DA05LP1 FN0AD268DG03RRM1.SCF FN0AD135BF01GGM1.SCF FN0AA162AH05SP1 FN0AD168AA12GGM1.SCF FN0AD168AA12RRM1.SCF FN0AD170DG10GGM1.SCF >CYP694A1 CYPK 37% TO CYPH MYIYIGIGVSLILLY TLVIKPLISLLLIKIKFGKQAKIIFYPIVGDIMEIEGSFKKYNDHYESLRRY FTENKDLKFILLNVFKTPLILIGDPEINKMIHQDHENYKKIDFLNNN (2) SRLMGQGLLYQSGQKWKSQRKLLGKPFDYDKL KARIPMMNQVVKQKLKNTYNNPLDLTRSIAGEVVIQTFFGQEAQDAQLNNREAQAEIV ELFNDVAEAIYGSVYGFLKWMILGEKQW KLFPNKLERDINRRIDELTQFARKVIDNRITSIKQEGFKK NQDDFDFLDIHLQEFLGSKNESGITKDEIISQFITLFFAGTDTTSSVAAMCLFYLAQN PDVYDALIKELENVVGDGDGDVLDQHLPKLQELNSFIWEVLRVRNPASGPLVRVAKQDL VLKDLHIKKGWILMPANFVQQQTDKYFENFKEFDHKRFLKAQAIKEDNGYVNIPFSAGPRNCIGQ (0) HMALMEIKIILCHILKTFKVITVPDKIKDLKWRAKFLYFYEPLDCI* FN0AA186DA09SM1.SCF_1 FN0AA276CC07LP1 FN0AA355CC03LP1 FN0AA35CH10LP1 FN0AA370BB04SP1 FN0AA94BF01SP1 FN0AC107CH04GGM1.SCF FN0AC139CD11RRM1.SCF FN0AC61AC10RRM1.SCF FN0AC80DG01RRM1.SCF FN0AC83BH03RRM1.SCF FN0AD106DA07RRM1.SCF FN0AD113AE08RRM1.SCF FN0AD129AG11GGM1.SCF FN0AD141AD09GGM1.SCF FN0AD212DB07RRM1.SCF FN0AD35CF09RRM1.SCF FN0AD35CF09GGM1.SCF >CYP694B1 CYPUa + CYPUb 45% to CYPH and CYPL MIFYIIIIFVFYVLYRIVLKPLIPLLILKLQFGKEAYLWYAPIWGLLKYNFRS LKQNGDFLDDLRKRMRENPQVKILLTNFLDTPFINFVDSEYIKKMYLEYQNFPKFNLLRYD (2) NLIDKGLLMTEGEEWRFQRTLLGLAFTFEKLKSRIPMINQTVKERCILDPKT NSFDFISWITGEVVIHSFFGEIAKGLTINGKPGQVEIVKLVADIMLQRFKNAYTQIKLMI LGNKGWRILATKKEKDINNRVDTLRNTVKQLIETRIQQLKGETEARKEKDKDQCFLDIYLCELLKQ QNEGSK KNIDFEPVLQQFLTLFFAGTDTT ATMTVTCLVYLAKYPDVQNELLEEIKDLMQDSDVQDTHLPKLVKMNAFIN (0) EVFRLKNPAFSPFVRLVQQDMQFL XXXXXXGWMVVQXXXXXXLLNEHFSNPEVFDYKRWLTGQGAIQSDNGFVHIPFGAGGRNCI GQHMAQMELKIILCHIIRKFQVSLNPDVQLKFGIRFLYGAEPDNCLIYKTRR* FN0AA32DC07LP1 FN0AA341BD09SP1 FN0AA65AE09LM2.SCF FN0AC124DB08GGM1.SCF FN0AC168BG07GGM1.SCF FN0AA154BF12SM1.SCF FN0AC90DG12GGM1.SCF >CYP694C1 CYPL 53% TO CYPH MLSIYIALASLIIAIIYFLVLLPLIPLLKIKMQLGSKAALMFYPLSGLNKIFNDS LAKERDLLKIINNQLKKNPQTVVILSNFIHKPVLVWTGAEYIKDIYLDHTSY VKVDPFMVESIAQKGMVLSEGEAWKRQRKFLGTAFTFEKLTSRLPMINQVVEKV SKSDPKTNLNQFTSRITGEVVIHSFFGDLAKGFQIEGKDAQIAIVEILSEIFLMPMNNPF IQLKQMLFEYKSWSIFPTKKEKQLLKRISDFKQVIMAMIEKRIEQLKNQQIENQDKMVFL DLYVTEYLKQQKENKQDMDAEEILHQFITLFFAGTDTTATTSGT CLYYLAQFPEMQEEILKEVIEVVGEQGDIKEEHLNKLVRVNALIQEVLRLRNPAFSPVFR TVRQDKQLLDVKMKKGWFSVAYHIGPGLLDKHFENAQEFDYKRWLNKGNVIKNDNGFIHI PFAAGPRNCIGQHMAVMEVKMIVARLVRQYKITLNPEVKDITFGMKFLYCVEPDNCLLYE ERNLQ* FN0AA205CG06LM1.SCF FN0AA218AF07LM1.SCF FN0AA351DG09SP1 FN0AC61AE09RRM1.SCF FN0AC66AA02RRM1.SCF FN0AC6AC12RRM1.SCF FN0AD105DB01GGM1.SCF FN0AD180AG09GGM1.SCF FN0AD198AF04GGM1.SCF FN0AD38CD04GGM1.SCF >CYP694C2 CYPH 32% to CYPG MWNIALVFLCLLIIATYIFIIRPLIPLLLLKAKLGDKAIFMFYPLFGFIGLFMKSI KTKNDAMETVNAALRKNPKAKIILSNLLHKPCIMLTGSEYLKDALTEHQHYEKMNPFMID SFIQTGLILSEGDRWKRQRMFLGQAFTFEKLKSRIQMMNQVVKEIVDKDP KTNLNEFMSKITGEIVIKSXFGELAEGLRLEGKEAQVALIQLTTDINLIQFENPFVLI KSLIFKERMWDVLPTKQEKDIVRRVNEVRTKVKEIISRRIEQLQENPIQDEDKMVFLDLY VTEYIKQQKQQQQLINVNEILHQFITLFFAGTDTTATTCGTCLYYLAQYPEIQTEILEEI QEVAGLDEIKEQHLNKLVKINALVQEVLRFKNPAFATIFRIVKNDMQLQDLKLKKGWAV VEMLNASSVQENYFENATEFNYKRWLNTTNIIKNDNGFIYIPFSAGQRNCIGQHMAMMEAKV IIALIVRKYQIILNPEVKQIKFGIKFLQCVEPDNCLLFEKRL* FN0AA163BA11SP1 FN0AC120AB05RRM1.SCF FN0AA71AA01LM1.SCF FN0AC29CH08RRM1.SCF FN0AC142BD03GGM1.SCF FN0AA5BA07LP1 FN0AD58CG07RRM1.SCF FN0AC139CA11GGM1.SCF FN0AA108BB06LM1.SCF FN0AD80CB04RRM1.SCF FN0AD111AF05GGM1.SCF FN0AC63CE07GGM1.SCF FN0AC181BB05RRM1.SCF FN0AC120AB05RRM1.SCF FN0AD3BB02FFP1 FN0AC125BG07RRM1.SCF >CYP694C3 CYPM 61% TO CYPH 59% to CYPL MEPILIAIFSLIMLMV YFLIIKPLVPLLLLKLQLGDKAILMFYPIFGFLGVLTKSIQINNDLMHSINHALRKNPKA KVILSNHLTKPFIMLTGSEYIKDSFLDHHDYEKMNPXMIPSFLQKGLVMSEGESWKRQRK FLGTAFTFEKLKSRLPMMNKVIEYISENDDKSH LNDFMARITGXXVIRSFFGELVEGFQLEGKDAQVALIQLTGEISIMQLQSAYYFI KYLLFKDRMFEVFPCKKEKEILRRVENIRMKLNELILKRIQQLKENPVQDQEKMVFLDLY VTEYLKQQKQNEQQIDLEEILHQFITLFFAGTDTTATTSGTCLYYLAKYPEIQSEILEEV NQVVGNADINEDNLNXLTKVNALIQEVLRL RNPAFVTLFRTVKRDKQVQDIKLKKGWALVQMQNASSIQDSHFDNATEFNYKRWFDKGNV VKNDNGYINIPFAAGPRNCIGQHMALMEAKIIIALLVRKYKILLNPDVQEVRFGVKFLQTV EPDNCLFFKKRIQ* FN0AA10CE03LP1 PART IS INVERTED ON OPP STRAND FN0AA10CE03SP1 PART IS INVERTED ON OPP STRAND FN0AA126BB03LM1.SCF FN0AA12CB12SP1 FN0AA186AF07LM1.SCF FN0AD102BE05RRM1.SCF FN0AD108AE03RRM1.SCF FN0AD113AE04GGM1.SCF FN0AD137BE12GGM1.SCF FN0AD277DG09GGM1.SCF >CYP694C4 CYPJ different gene 84% to CYPI 91 MQTLVMAFIIILLLALFFIIIQPLVPLLLLRVKLGDKAIMMFYPIFGFIGIFMRSIKTNQ 270 271 DVTKSINVALRNNPRAK IILSNFLNKHCIMFAGTEYLRQSYQDHDDFEKLDPFMLPSFIQKGLVMSEG 474 ENWKRQRKFLAPAFTFEKLKSRLPMMN QVVEDIAEKYYKTNLNDFMSRITGEIIVKSSFGKLGEGFQLEGKEAWVALTKLTGEISLI MMDNLYAFVKSLLFGVKTWTILPTKQEKDVVRRVENVRIKLNELILNRVEQLKDSPVQDQ DKMVFLDLYVTEYLKQKKQNEQQIDLEEILHQFITLFFAGTDSTATICGTCLYYLAKYPE IQSEILEEVNEVIGNADINEDNLNKLIKVNALIQEVLRLRNPAFVTLFRTVKRDKQVQDI KLKKGWALV FN0AA216CA04SM1.SCF FN0AA190CC10SM1.SCF FN0AA190CH06SM1.SCF FN0AA377AB02LP1 FN0AA377AB02SP1 very like CYP694C5 except in 1st 45aa FN0AD130CC02GGM1.SCF FN0AC117AF02RRM1.SCF 2 diffs to CYP694C5 FN0AD211DF09RRM1.SCF 3 diffs to CYP694C5 >CYP694C5 CYPI + CYPV 72% to CYPM 88% to CYPJ MLTLFIAIVIVLSLALFFIFIQ PLVPLLLLKLKLGNKAIIRFNPILGFI GIFMRSIKTNQDVTKSINVALRNNPRAKIILSN FLNKPCIMFAGTEYLKQSYQDHDDFEKLDPFMLPSFIQKGLVMSEGENWKRQRKFLAPAF TFEKXKSRLPMMNQVVEDIAEKDDKTNLNDFMSRITGEIVVKGFFGKLAEGFQLEGKDAQ IALTNLTGEISLIVMENLYSFVKSLLFGVKMWKILPSKQEKDLVRRVENVRIKLNDLILK RIEQLKDNPVQDQDKMVFLDLYVTEYLKQQAQNEQQIDLE EILHQFITLFFAGTDTTATVCGTCLYYLAKYPEIQSEILEEVNEVIGNADINEDNLNKLI KVNALIQEVLRLXXXXFVXXFRXVKXDKQVQXIK LKKGWALVQMQNASSIQDTHFDNATEFNYKRWLSKDSIIKNDNGYIHIPFTAGPR NCIGQHMALMEAKIIIALLIRKYKILLNPAVQQIRFGIKFFQCVEPDNCVLFEKRI* FN0AA133CH05SP1 FN0AC35BE02RRM1.SCF FN0AD137BE12RRM1.SCF FN0AA63DH11SM1.SCF FN0AD277DG09RRM1.SCF FN0AD211DF09GGM1.SCF FN0AD162AE09GGM1.SCF FN0AD162AE09RRM1.SCF FN0AA190CH06LM1.SCF FN0AA98DA04LP1 FN0AC155CA06RRM1.SCF FN0AA322AH03LP1 presumed poor quality seq of CYPI = CYPIb FN0AA314DB09SP1 FN0AC238DA05RRM1.SCF 3 diffs FN0AA314DB09LP1 FN0AA63DH11LM1.SCF FN0AD121BE03GGP1 3 diffs, might be CYPJ C-term >CYP695A1 CYPX 37% to CYPN 35% to CYPK MLFQILLILLGLLISWFVIK PLVIMMKLKLQFGSTCKIQFGIFGILGLSSQSIIEKMKRKSIPKTVKFIVHNYASAVYIL IIDPDYYQFMLNNHENYSQINDLNT (2) SQLLDEGIMFQQGERWKQQRELLIQYFDIDKLKRNLPKLNEIIKQNFKQYDYQNDQIQT TLLIIISDILIQSFFGQDANKLLINNKCIGLETTDLFEALSKLSRKPYSICKNILFGVQA LKMFPSSEEQIIQTKINNIKFTIEKIIQKRIVQHELKLDEDENEISQMSEDI (fs?) LIYIFEPIFKLKXXNNRMSFEEI KQQYFTIFKIGSQTTNQIIQASLHYLAEQPQIQNELRQEILSICKTDIISYQE LKSLVKLSAFLNEVLRFVNPIPIVRKVQTTHFIKDLKLKR (1) NWVVMVDNSVT NSSEKYYDNPKEFNYQRWLQSESIKENNNYVFIPFSNGPRNCVGQSLATMIYQIILINIL RNFEVNVNEKSKNNKSITFVLQNSSFKLSPISQK* FN0AD274BG04RRM1.SCF 44% to CYPN FN0AA46AG10SM1.SCF FN0AA9AE11SP1 FN0AA266AC10LP1 FN0AD142AG12RRM1.SCF FN0AD49BC11RRM1.SCF FN0AD113AF08GGM1.SCF FN0AA334AB01LP1 FN0AD159BG08RRM1.SCF >CYP696A1 CYPQ 47% TO CYPN MIIYVLYAVLGLILYLFVMKPLTEMIKLKFQFGKECKICFTVFGKEIFDQLKETKENKNPRDIFNKQK TAYNKYQYKFFVTNMLWIIRISIADPLYQKEALINHDLYQKVDPVCHN (2) DLLSKGLVWSKGEQWKKQRKLLSSSFEFDALKKKVPMINEITQSKIEKFSNENV LSSLQSITGLIVIKSFFGIQTDQIYI NNTELQVEIANIMNEMAYMRFKSQIQSTKRLIFGTKAWKIFPTKEEKRLLQRVKDMRSIVGDLVQQRIKYFEDS NNSKNNTINENFLNILVNEYLKITNKQQQEATFDQIIQEFITLQFAGTDTTAVLLHHCLY FLASYPQAQDEIRGEVNRCCPSSFINENEINNLKRLSAFISEVLRLKNPAMRPIIRVATQ DHKIKDLQIKK (1) GWLVCIDYFLQNQSEKHFENAGQFDYTRWLQDS PIKDDNNLIYIPFSAGPRNCIGSQMALL EVKIILGQILKQYQITRNTNVEVSWEIHFNHQLSPTNAVILNKIK* FN0AA177DF04SP1 FN0AA227DG02LP1 FN0AA231BF11LP1 FN0AA240BE12LP1 FN0AA346DG10SP1 FN0AA79DD07SP1 FN0AA87BF11SP1 FN0AC119BC04RRM1.SCF FN0AC154AD07GGM1.SCF FN0AD128BB05RRM1.SCF FN0AD225AF01RRM1.SCF >CYP696B1 CYPYa + CYPYb 47% to CYPN MIIQIFAILIVLFFYVFVLKPLCPMIKLKMQFGQDCKMQYNFLGRDIWKRLRDLKI FNDIFWSDKEEYKRLPYKFKVSNSFWKIQIQVADPEYYKQILHNPHYYEKANNXADK (2) HLLQKGLVFETRDQWKAQRNILADQFQYQQLTSRLPMINKIILDGITKIGSANNLF EQLELMTGKVVIQSPFGDSIDGLKVNNKDLQVEVTELINDMGESRFKSKYVFIKRLLLGT WAWNIFPTQEEMMIQQRVFQLKTMIEKVIRKRLIELRQRNKQNDQKDLNLFLDILL NDYIKNDHKKQESQAIDEVIQQFITLLFT XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX LKQLIKLSALINEALRLKNPAVNLLMRNSTQTHQVKDLTIQK (1) NWRVIVNFQF QLLSEKNFKNPEDFDYKRWLTPSPILNNNNFVYLPFSAGQRNCIGQHMALMEAKIILSQI LKQYYIKPNMNVNPMWNLRFILQLQPGNCMKL FN0AA281CB07LP1 FN0AA367BD11SP1 FN0AD137AF02RRM1.SCF FN0AD162AB07GGM1.SCF FN0AA34CB12LP1 >CYP696C1 CYPN 37% TO CYPH MIIHIILALFLLMFYLLVV KPLVPMIKLKMQFGDACLMKYHLFGGELWEALKEMKTSKDLFKRHRDLYMNHPYKIFV TNFLWKVRINVADPEYYKLMLTNHQYYSKFNNINH (2) DNVIQNGLICQMGEK WRAQRLLLSESFDYHQLKSRLPMINEVCLDKINSIHGENILEFLELITGQVVIRSFFGKSAD GVQINKKKIQIEIADLLNELGEVRFKSKYLFVKRFFLGTKSWGFFPTNKEKELL QRISEMRLAIEKLIQKRIVEIELKMDENEDEIKQRETDFLDV LIKEYLKQKKQGTQKITIDEIIQQFITLFF AGTDTTAVLSYHCLYYMAQYPEMQDEIREEVLTICKNESILDDKIKQLHKLSAFINEVLR FKNPALRLMMRFCNQTHQVKDLTIQK (1) GWSVTIDYQFPQWLPKHFPNPEKFD YKRWLEKEPIKENHQFVYLPFSSGPRNCIGQHMALMEAKIILSQILRQYSIEINHD VDSRWTARFLYQLQPGNCVKLQKR* FN0AA12DB07LP1 FN0AA214BD08SM1.SCF FN0AA22BD12LP1 FN0AA238BG12LP1 FN0AA241AH11SP1 FN0AA28AG05SP1 FN0AA30DF10SP1 FN0AC45CB03RRM1.SCF FN0AC153DH12GGM1.SCF FN0AC75CH09RRM1.SCF FN0AC84DH09RRM1.SCF FN0AD102CF03GGM1.SCF FN0AD139BF07RRM1.SCF FN0AD233BB09GGM1.SCF FN0AD236DE03RRM1.SCF     FGHWX  M N   N O Y Z i j z {     + , ? 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