>4C3m AC014779 73845-80196 also AC008219
MSSKVITSLMAESILLSKVGQVISGYSPITVFLLGSILIFLVVYNKRRSRLVKYIEKIPG
PAAMPFLGNAIEMNVDHD (1)
ELFNRVIGMQKLWGTRIGINRVWQGTAPRVLLFEPETVE (0)
PILNSQKFVNKSHDYDYLHPWLGEGLLTSTDRKWHSRRKI (0)
LTPAFHFKILDDFIDVFNEQSAV
LARKLAVEVGSEAFNLFPYVTLCTLDIVC (1)
ETAMGRRIYAQSNSESEYVKAVYG (2)
IGSIVQSRQAKIWLQSDFIFSLTAEYKLHQSYINTLHGFSNMVIRERKAELAILQENNNNNNNNAPD
AYDDVGKKKRLAFLDLLIDASKEGTVLSN (0)
EDIREEVDTFMFEGHDTTSAAISWTLFLLGC
HPEYQERVVEELDSIFGDDKETPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNI (1)
GGKIVPAGTQAIIMTYALHRNPRVFPKPEQFNPDNFLPENCAGRHPFAYIPFSAGPRN
CIGQKFAILEEKAVISTVLRKYKIEAVDRREDLTLLGELILRPKDGLRVKITPRD

>4C3ps D. pseudoobscura ortholog of Cyp4c3 94% intron 3 missing
MSSKVISSLMAESILLTKMAQVISGYSPITIFLLASIALFLVVYNKRRSRLVKHIEKIPG
PAAMPFLGNAIEMNVDHD (1)
ELFNRVIGMQKLWGTRLGINRVWQGTSPRVLLFEPETVE (0)
PILNSQKFVNKSHDYDYLHPWLGTGLLTSTDRKWHSRRKILTPAFHFKILDDFVDVFNEQSAV
LARKLAVEVGSEAFNLFPYVTLCTLDIVC (1)
ETAMGRRIYAQSDSESEYVKAVYG (2)
IGSIVQSRQSKIWLQSDLIFRLTADYKLHQSYINTLHGFSNMVIRERKSELALLQDNNNNNNNTPDA
YDDVGKKKRLAFLDLLIDASKDGTVLTN (0)
EDIREEVDTFMFEGHDTTSAAISWTLFLLGCH
PEYQEQVAEELDSIFGNDKETPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNI (1)
GGKLVPAGTQAIIMTYALHRNPRVFPKPEQFNPDNFLPENCAGRHPFAYIPFSAGPRNC
IGQKFAILEEKAVISTVLRKYKIEAVDRREDLTLLGELILRPKDGLRVKITPRD

>4d1m AC017770 49988-51720
MFLVIGAILASALFVGLLLYHLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKK
IFEFMETYSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKEGLL
VSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWIN
LCTMDTIC (1)
ETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARA
EKKALNVLHQFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDERP
LSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSY
ELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEI (1)
NGKLIPAGTNIGISPLYLGRREEL
FSEPNIFKPERFDVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVD
FVGDSSEPPVLIAELILRTKEPLMFKVRERVY

>4D1ps ortholog with one N-terminal exon found by Michael Mohler 86%
MFLLLGALLA SGLFVALLVY QLKFKRVIEV ISYMPGPPVL PLVGHGHHFI GKPPHELVKQ
ITEFMSKYAK DETLKVWLGP ELNVLMANPK DVEVVLGTMR FNDKAGEYKA LEPWLKEGLL
VSRGRKWHKR RKIITPAFHF KILDQFVDVF ENGSRDLLRN MEMDRLRQGQ TGFNLYDWIN
LCTMDTIC (1)
ET AMGVSINAQT NADSEYVQAV KTISMVLHKR MFNIFYRFDL TYMLTPLARA
EKRALHVLHE FTEKIIVQRR EELIRGGSKD AAAASDDADA DVGAKRKMAF LDILLQSTID
EKPLTNLDIR EEVDTFMFEG HDTTSSALMF FFYNVATHPE AQKKCFEEIS SVIGQDKSTP
VTYELLNKLH YVDLCIKETL RMYPSVPLLG RRVVEECEI (1)
N GKRIPAGTNI GISPLYLGRR
EELFSEPNSF KPERFDVVTS AEKLNPYAYI PFSAGPRNCI GQKFAMLEIK AIVANVLRHY
HIDFVGDTTE PPVLIAELIL RTKDPLLFKL QDRVY

>4d1malt splice AC017770 48817-51720
MWLLLSLVLLLAIIALEMRRFLRNMRTIPGPLPLPLLGNAHIFLGLTPAEACLKIGELAE
RHGDTFGLFLGPSYSVMLFNPRDVERVLGSSQLLTKSQEYSFLGRWLNEGLLVSNGRKWH
RRRKIITPAFHFRILEPYVEIFDRQSLRLVEELALRISRGQERINLGEAIHLCALDAIC (1)
ETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALNVLH
QFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDERPLSNLDIREE
VDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYV
DLCVKETLRMYPSVPLLGRKVLEDCEI (1)
NGKLIPAGTNIGISPLYLGRREELFSEPNIFKP
ERFDVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPP
VLIAELILRTKEPLMFKVRERVY

>4D1psalt ortholog with alternative splice exon 1 found by Michael Mohler 80%
MWLSLVFGAVGTVLVLGLFSWLPFCRRRRRISELAELLPGPKPW
PLLGDAHLFFGLSPAEACLMMGQLAEKY
GDTFKLRLGPCFSVMFFHPSDVEQVLSSTQLVDKADEYDFLARWLNEGLLVSTGRKWHKR
RKIITPAFHFRILEQYVEIFDRQTHQFLSNLDLARGKDDNLVNLGHAVHLCALDVIC (1)
ETAMGVSIN AQTNADSEYV QAVKTISMVL
HKRMFNIFYR FDLTYMLTPL ARAEKRALHV LHEFTEKIIV QRREELIRGG SKDAAAASDD
ADADVGAKRKMAFLDILLQSTIDEKPLTNLDIREEVDTFMFEGHDTTSSALMFFFYNVAT
HPEAQKKCFE EISSVIGQDK STPVTYELLN KLHYVDLCIK ETLRMYPSVP LLGRRVVEEC
EI (1) 
NGKRIPAG TNIGISPLYL GRREELFSEP NSFKPERFDV VTSAEKLNPY AYIPFSAGPR
NCIGQKFAML EIKAIVANVL RHYHIDFVGD TTEPPVLIAE LILRTKDPLL FKLQDRVY

>4d2m AC017770 comp(32267-34028)
MLGVVGVLLLVAFATLLLWDFLWRRRGNGILPGPRPLPFLGNLLMYRGLDPE (1)
QIMDFVKKNQRKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGR
KWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIA (1)
ETAMGTKINAQKNPNLPYVQAVND (2)
VTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAI
KVMHDFTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDED
IREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGE
LKFMENVIKESLRLHPPVPMIGRWFAEDVEI (1)
RGKHIPAGTNFTMGIFVLLRDPEYFESPD
EFRPERFDADVPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPR
HSMNIVLRSANGVHLGLKPRA

>4D2ps ORTHOLOG 79% TO 4D2
MLALVVFLVALTTVLVWDYFWRKRRNDILHYMPGPRGLPLVGNALMYRGLDAE (1)
QIMGFVSKNRNKYGPLYKVWVLNQLAVFSTDPHDIEFILSSQQHITKNNLYELLHCWLGTGLLMSTG
KKWHSRRKIITPTFHFKILEQFVEIFDQQSAVMVGQLQQRADGKTAINIFSVVCLLALDIIA (1)
ETAMGTKIQAQMSPNLPYVQAVTD (2) 
VTNIMTTRFIHAWQRIDWLFRLVHPGMAKRQDSAIKVMHDFTENIIKQRRQALVSAGKQEKEKEEIK
EDDDLGQKRRMALLDVLLQSTIDGASLSNDDIREEVDTFMFEGHDTTTSAISFCLYEISRH
PQVQQLLVEEIHEVLGVDRHRPVTLRDLGELKYLENVIKESLRLHPPVPMIGRWFNEDVEI (1)
RGKRIPAGTNYTVGIFVLLRDPEYFESPDEFKPDRFDSTSPQTHPYAYIPFSAGPRNCIG
QKFALLEMKSTISKLLRNFELLPLGPEPRPAMNIVLRSANGVHLGLQPRSVLAS*

>4d8m AC017388 comp(37292-39859) also AC010557 AC010112 AC010113
MLLFLLVVLLFGAGWIIHLGQADRRRKVANLPGPICPPLIGAMQLMLRLNPK (1)
TFIKVGREYVLKFGHLQRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWLGNGLLLSDGK
VWHQRRKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKANGNTFDVYRSICAAALDIIA
ETAMGTKIYAQANESTPYAEAVNE (2)
CTALLSWRFMSVYLQVELLFTLTHPHLKWRQTQLIR
TMQEFTIKVIEKRRQALEDQQSKLMDTADEDVGSKRRMALLDVLLMSTVDGRPLTNDEIR
EEVDTFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELK
YMECVIKESLRMYPPVPIVGRKLQTDFKY (1)
THSVHGDGVIPAGSEIIIGIFGVHRQPETFP
NPDEFIPERHENGSRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQR
VECIVNIVLRSETGFQLGMRKRKHN

>4d8ps orth  D. pseudoobscura Van Alstine and We Liu 79%
MLLLVLVLLLVAVGWLVHRGQAERRRAVSNLPGPMCPPLLGALHIMSSMNPK (1)
TFIKVSGENMRKYG
PLQRVWILNRLLIMSADSEINEQLLSSQEHLVKHPVYRVLGKWLGNGLLLSDGKV
WHQRRKIITPTFHFSILEQFVEVFDQQSNVCVERLAPRANGQTFDVYRPVCMAALD
IIAETAMGTKIHAQAAESTPYAEAVNE (2)
CTALLSWRFISVYLQVELLFTLTHPYMKWRQTQLIRTMHDFTTKVIEERRRTLEEQQ
GSKLSPSPDDDVGRKRRMALLDVLLLATVDGRPLTNDEIREEVDTFMFEGHD
TTTSALSFCLHVLARHPQVQEKMLEEILRVIGTDRKRPVTIRDLNEMKYLECVIKESLRL
YPPVPLVGRKLQTDFKY (1)
SHSKYGDGVIPAGSEFLIGIYGMQRNKNEFAQSEEFIPERHENGERFSPFTFIPFSA
GPRNCIGQKFAQLEMKMMLAKIVREYELLPLGEPVECVINIVLRSD
TGFQLGMRRRNDTQ*

>4d14m AC017770 35699-37438 missing intron 3
MYLELFAILLATALAWDYMRKRRHNKMYAEAGIRGPKSYPLVGNAPLLINESPK (1)
TIFDMQFRLIAEFGKNIKTQMLGESGFMTADSKMIEAIMSSQQTIQKNNLYSLLVNWLGDGLLISQ
GKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKTVINMFPVACLCAMD
IIAETAMGVKINAQLQPQFTYVQSVTT (2)
ASAMLAERFMNPLQRLDFTMKLFYPKLLDKLND
AVKNMHDFTNSVITERRELLQKAIADGGDADAALLNDVGQKRRMALLDVLLKSTIDGAPL
SNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMK
LLGELKYLECVIKESLRLFPSVPIIGRYISQDTVLDGKLIPADSNVIILIYHAQRDPDYF
PDPEKFIPDRFSMERKGEISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPL
GEEVQPVLNVILRSTTGINCGLKPRVY

>4d14ps D. Pseudoobscura K. Earhart 79%
MFVELLVLLLTVALVWDYLVGRKHKRLFDRAGITGPKAWPLVGNAPLMINESPK (1)
TVFDLQWRLIQTHGKNVRCQILQDRGFMTADPKMIEAIMSSQQTIQKNNLYGLLVNWLGDGLLLSK
GKKWFRRRKIITPAFHFKILEQFVEVFDQQSAIMAKNLYDRADGKTVINMFPVACLCAMD
IIAETAMGVKINAQLQPNFPYVQSVKT (2)
ASGMLAERFVNPAQRLDISMRLFFPSAFAKLSA
NIKAMQDFTNNVISERRDLLQKSISDGTYETTNASPLDDVGQKRRMALLDVLLQSSIDGA
PLSNEDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVLGDEKDAPVN
IQLLGELKYLECVIKESLRLFPSVPIIGRHIVEDTLL (1)
DGKLIPAKTDVMILIYHSQRDPDYFPEPNKFVPERFSPERKGEINPFAYTPFSAGPRNCIG
QKFAMLEMKSTISKMVRHFELLPLGEDVQLVLNLILRSTTGINVGLKPRVY

>4d20m AC019509 comp(19731-21636)
MWLTLITGALILLLTWDFGRKRQRVLAFEKSAIPGPISIPILGCGLQALHLGAE (1)
NIIGWVGEKFDKYGKTFRFWILGESLIYTKDLQYFETILSSTTLLEKGQLYEYLRPFLNDGLLVST
GRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALDVIT (1)
EAAMGVQVNAQNDPDFPYIKALKS (2)
VVYIQPDRMFRFSRRYNWLFPLAAPLLHRQLLSDIRVMHDFTDKVISERRETVRRAKADGTYRPL (1)
SLGDAEIGSKSQMALLDILLQSSINNQP
LSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQ
AQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKTIPANTSIYLVLYYAHRDANY
FPDPLSFRPERFLEDQEQGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLP
LGEELKPMLNFILRSASGINVGLRPRKALR

>4D20ps ORTHOLOG 74% TO 4D20 same as below Contig1058_Contig8213.5
MLLLTLAFGALAVLLTWDFVRKRQRAATLERSKISGPLSLPVLGNGLQALDLGAE (1)
NIVDWVEESFRLYGKTFRMWILGESLIYTKDLKYFEAILGSTTLLQKGQLYKFLRPFLNDGLLLSV
GKKWHARRKVFTNAFHFNVLGHYVDIMDRQAAVMVEKLRQVADGETTVDMLPYVSLAALDVIT (1)
EAAMGVQVNAQSDSEFPYVQALKS (2)
VVYIQSDRMFRFLQRYDWLFRLTCPVLRSKLLKDVRVMHDFTDKVIRERRAAVEQAKADGSYRPL (1) 
SLGDPEVGRKSQMALLDILLQATIEGQP
LSDADIREEVDTFMFEGDDTTSSGVSFALYAIARHPQVQARIYRELLQVLGRDPSTPVTQ
AKLQELKYLDCVIRETLRLYPAVPAVGRYTSKEIQIGGQTIPANTSIYLVLYFAHREAEF
FPDPLAFKPERFLDRADSEDRETFAYLPFSAGPKNCIGQKFAMLEMKALVSKVLRCYELL
PRGPEVKPMMNFILRSSTGMNVGLRPRRSP*

>4d21m AC020004 55466-57280
MWILLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPFTIPIVGNGLQALTLRPE (1)
NFIQRFGDYFNKYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGDGLLLST
GNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTT (1)
ETAMGVQVNAQNEPNFPYTKALKS (2)
VVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIAIMQDFTDKVIRERRAILERARADGTYKPL (1)
IMGDDDIGGKAKMTLLDILLQATIDNKP
LSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQ
TKLLELKYLDCVIKETMRLHPPVPILGRYIPEDLKIGEITIPGNTSILLMPYYVYRDPEY
FPDPLVFKPERWMDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYELL
PLGADLKATYTFILSSSTGNNVGLKPRTRVK

>4e1m AC020402 44580-46698
MWIVLCAFLALPLFLVTYFELGLLRRKRMLNKFQGPSMLPLVGNAHQMGNTPT (1)
EILNRFFGWWHEYGKDNFRYWIGYYSNIMVTNPKYME (0)
FILSSQTLISKSDVYDLTHPWLGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENST
KFIDQLKKVADGGNIFDFQEEAHYLTLDVICDTAMGVSINAMENRSSSVVQAFKD (2)
ITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEIIAKRIEVRKSGLEVGIKADEFSR
KKMAFLDTLLSSKVDGRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQ (0)
EKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVI (1)
DGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQ
PERFDREKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGY
ISTTLGLQPAEKKSRDAHNHKYDPILSASMTLKSENGLHLRMKQRLVCDST

>4e1ps D. pseudoobscura ortholog of 4e1 T. Liu INTRON 4 MISSING 73% to 4e1
MWFALYLVLALPLLWLAYLELKSLRRRRVLNKFKGPKVLPVVGNAHQLGRTPP (1)
EILGQMFEWWYQHDKDNFRYWIGYYPNLMVTRTKYFE (0)
FILSSQTLISKAEVYSLMQPWLGLGLLTSTGSKWHKHRKMITPSFHFNVLQDFHEVMNEKS
TKFIKHLKNVSGGGSIVDFQEQAHFLTLDIICETAMGVSINAMENQDSELVQAFKD (2)
MCYNIKVRTFSSWKRNPTLYQFASDYPAYCKTL
KTLQDFTHDVIEKRLNAHKEGTVLASHGDEFSRKKMVFLDTLLSATVDGRPLTSQELYEE
VSTFIFAGHDTTTSAISFTLYLVSRHQDDEQR
KLFEEQRDVMGDSGLDREATFQEISEMKYLDLFIKEAQRVYPSVPFVGRYTEKDYVI (1)
DGDLVPKGTTLHMGIFMLGYDDRVFKEPHKFRPQRFEEEKPGPFEYVPFSAGPRNCIGQKFAL
LEIKTVVSKIIRHFEVLPALDELASKDGYIRTTLGLPPTEKRKRDLQQHKYDPILLVAMS
LKSENGIYLRLKERF*

>4e2m AC020402 41848-44099
MWFVLYIFLALPLLLVAYLELSTFRRRRVLNKFNGPRGLPLMGNAHQMGKNPS (1)
EILDTVFSWWHQYGKDNFVFWIGTYSNVLVTSSKYLE (0)
FILSSQTLITKSDIYQLTHPWLGLGLLTST
GSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLD
VICDTAMGVSINAMENRSSSIVQAFKD (2)
MCYNINMRAFHPLKRNELLYRLAPDYPAYSRTL
KTLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKELYEE
VSTFMFEGHDTTTSGVSFAVYLLSRHQDEQ (0)
RKLFKEQREVMGNSELGRDATFQEISQMKY
LDLFIKEAQRVYPSVPFIGRFTEKDYVI (1)
DGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKPGPFEYVPFSAGPRNCIGQKFALLE
IKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRLKERH

>4e2ps pseudoobscura Ajit Narang INTRON 4 MISSING 86% to 4e2
MWFVLYLFLALPLLLVAYLELSTFRRRRALNKFKGPSRLPIVGNAHQAGKNPT (1)
EILDQVFSWWHQYGKDNFRFWIGSYSNLIITNHKYLE (0)
FILSSQTLITKSDIYNLTHPWLGLGLLTST
GSKWHKHRKMITPSFHFNILQDFHEVMNENSTKFIKQLKQVAAGDSIFDFQNETHYLTLD
VICDTAMGVSVNAMENRSSSIVQAFKD (2)
MCYCINMRAFHPFKRNDLFFRLAPDYPAYCKTL
KTLQDFTNNIIEKRIKAHKDGTVSASQGDEFSRKKMAFLDTLLSSTIDGRPLTTQELYEE
VSTFMFEGHDTTTSGVSFAVFLLSRHKDEQRKLFDEQREVMGDSGMDRDATFQEISEMKY
LDLFIKEAQRVYPSVPFIGRYTEKDYII (1)
EGDLVPKGTTLNLALVMLGYNDRVFKDPHKFR
PERFELEKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRHFEVLPALDELASKDGY
ISTSLGYPPEERKKRDLLRHKYDPLLSAVLTLKAENGLFIRLKERH

>4e3m AC020324 73117-75125
MWLAVLALLVLPLITLVYFERKASQRRQLLKEFNGPTPVPILGNANRIGKNPA (1)
EILSTFFDWWYDYGKDNFLFWIGYSSHIVMTNPKQLE (0)
YILNSQQLIQKSTIYDLLHPWLGHGLLTSF
GSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLD
VICDTAMGVPINAMEQRDSSIVQAFRD (2)
MCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTL
KTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSSTIDGRPLTRQEIYEE
VSTFMFEGHDTTTSGVSFSVYLLSRHPDVQ (0)
RKLYREQCEVMGHDMNRSVSFQEIAKMKYL
DLFIKEAQRVYPSVPFIGRYCDKDYDI (1)
NGSIVPKGTTLNLALILLGYNDRIFKDPHHFRP
ERFEEEKPAPFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRL
NTYLGLAPDEKLKREAGRHKYDPILSAVLTLKSDNGLHLRLRERRS*

>4e3ps D. pseudoobscura ortholog of Cyp 4e3 M. Nooh 81% 
MWLAVLALLALPLLVLVYFELRASRRRRMLKVFNGPAPVPVLGNANRVGNTPA(1)
EILATIFDWWQEYGKDNFVFWIGYTPHLAVTNPKYLE (0)
YILNSQSLIQKSTIYELLHPWLGYGLLTSH
GSKWHKHRKMITPSFHFNILQDFHEVMNENSTKFIAQLRRDAAGDSIIDFQDHAHYLTLD
VICDTAMGVPINAMEHRNSAIVQAFKD (2)
MCLSVNMRAFHPFKRSNRIYSLSPEYAAYQRTL
KTLQDFTYDIIEKRVETLQAGQNSSSADSSSPRKKMAFLDTLLSSTVDGRPLTRQEIYEE
VSTFMFEGHDTTTSGVAFAGYLLSRHPEAQ (0)
QRMYQEQCNVMGSELDRDATFQEIAQMKYLDLFIKEAQRVYPSVPMIGRYADKDYMI (1)
NGTLVPKGTTINLALVLLGYNDRIFKDPHHFRP
ERFEEEKPGPFEYVPFSAGPRNCIGQKFALLELKTVISKLVRSFEVLPAVDELLSTDGQL
NTYLGLSPAEKQKREAGRHKYDPILSAVLTLKSDNGLHLRLRERRH

>4g1m AC020093 comp(33262-34932) no introns
MAVEVVQETLQQAASSSSTTVLGFSPMLTTLVGTLVAMALYEYWRRNSREYRMVANIPSP
PELPILGQAHVAAGLSNAEILAVGLGYLNKYGETMKAWLGNVLLVFLTNPSDIELILSGH
QHLTKAEEYRYFKPWFGDGLLISNGHHWRHHRKMIAPTFHQSILKSFVPTFVDHSKAVVA
RMGLEAGKSFDVHDYMSQTTVDILLSTAMGVKKLPEGNKSFEYAQAVVDMCDIIHKRQVK
LLYRLDSIYKFTKLREKGDRMMNIILGMTSKVVKDRKENFQEESRAIVEEISTPVASTPA
SKKEGLRDDLDDIDENDVGAKRRLALLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDT
TSAGSSFALCMMGIHKDIQAKVFAEQKAIFGDNMLRDCTFADTMEMKYLERVILETLRLY
PPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRPDIYPNPTKFDPDNFLPERMA
NRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYIVHSTDTEADFKLQADIILKLE
NGFNVSLEKRQYATVA

>4G1ps ortholog NO INTRONS 93% IDENTICAL TO 4G1
MTVDTVQETLQHAATSTSGLGFSPMLTTLVGTIVALGLYEYWRRNTREYRMVANIPSPPG
LPLLGQAHMVAGLSNAEILNVGLGYLNKYGETMKAWLGNVLLVFLTNPNDIELILSGHQH
LTKAEEYRYFKPWFGDGLLISNGHHWRHHRKMIAPTFHQSILKSFVPTFVDHSKSVVGRM
GLETGKSFDVHDYMSTTTVDILLSTAMGVKKLPEGNKSFEYAQAVVDMCDIIHKRQVKLL
YRLDSIYKFTKLREKGDRMMNIILGMTSKVVKDRKQNFQEESRAIVDEVQAVSTPATKKE
GLRDDLDDIDENDVGAKRRLALLDAMVEMAKNPDIEWNEKDIIDEVNTIMFEGHDTTSAG
SSFALCMMGIHKDIQEKVFAEQKAIFGDNMLRDCTFADTNEMKYLERVILETLRLYPPVP
LIARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRADIYPNPTKFDPDNFLPERMANRHY
YSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYIVHSTDTEADFKLQADIILKLENGFN
ISLEKRKYATVA

>4g15m AC013897 comp(8972-10574 and 5306-6643) two pieces
MEVLKKDAALGSPSSVFYFLLLPTLVLWYIYWRLSRAHLYRLAGRLPGPRGLPIVGHLFDVIGPAS (1)
SVFRTVIRKSAPFEHIAKMWIGPKLVVFIYDPRDVELLLSSHVYIDKASEYKFFKPWLGDGLLIST (1)
GQKWRSHRKLIAPTFHLNVLKSFIELFNENSRNVVRKLRAEDGRTFDCHDYMSEATVEILL (1)
ETAMGVSKKTQDKSGFEYAMAVMRMCDILHARHRSIFLRNEFVFTLT
RYYKEQGRLLNIIHGLTTKVIRSKKAAFEQGTRGSLAQCELKAAALERER
EQNGGVDQTPSTAGSDEKDREKDKEKAS
PVAGLSYGQSAGLKDDLDVEDNDIGEKKRLAFLDLMLESAQN
GALITDTEIKEQVDTIMFEGHDTTAAGSSFFLSLMGIHQDIQDRVLAELDSIFGDSQRPATFQ (0)
DTLEMKYLERCLMETLRMYPPVPLIARELQEDLKLNSGNYVIPRGATVTVATVLLHR
NPKVYANPNVFDPDNFLPERQANRHYYAFVPFSAGPRSCV (1)
GRKYAMLKLKILLSTILRNYRVYSDLTESDFKLQADIILKREEGFRVRLQPRTS

>4G15ps ortholog (94%) intron #4 missing, black region does not match
MEVLKKDAAMGSPSSVFYFLLLPTLVLWYIYWRLSRAHLYRLAGRLPGPRGLPIVGHLFDVIGPAS (1)
SVFKTVIRKSAPFEHIAKMWIGPKLVVFIYDPRDVELLLSSHVYIDKASEYKFFKPWLGDGLLIST (1)
GQKWRSHRKLIAPTFHLNVLKSFIELFNENSRNVVRKLRAEDGRTFDCHDYMSEATVEILL (1)
ETAMGVSKKTQDKSGFEYAMAVMRMCDILHARHRSIFLRNEFVFTLT
RYYKEQGRLLSIIHGLTTKVIRSKKAAFEQGTRGSLAQCELKAAALERER
GQEQKQEQKQEQAEMGSAGGGKAAGEGT
PVAGLSYGQSAGLKDDLDVEDNDIGEKKRLAFLDLMLESAQN
GALITDTEIKEQVDTIMFEGHDTTAAGSSFFLSLMGIHQEIQDRVIAELDGIFGDSQRPATFQ
DTLEMKYLERCLMETLRMYPPVPLIARELQEDLKLNSGDYVIPRGATVTVATVLLHR
NPKVYTNPNVFDPDNFLSERQANRHYYAFVPFSAGPRSCV (1)
GRKYAMLKLKILLSTILRNYRVYSDLSESDFKLQADIILKREEGFRVRLQA

>4p1m AC018129 comp(67703-69662)
MIILWLILALSALLYWLHRANKDYHILSFFTKRIRLKDGTPVEIIAPIAKGKTIFGNTLDLYGRDH (1)
AGVFNYSRERAKEMGTSYIEYVFGKAIYNIIDADSAENVLNHPNLITKGLVYNFLHPFLRTGLLTST (1)
GKKWHARRKMLTPTFHFNILNQFQEIFK (2)
TESQKFLLQFEGQDEVTITLHDVIPRFTLNSIC (1)
ETAMGVKLDEMAEKGDRYRENFSQIEECFIRRLSNPLLWGDKLFEM
FAAKDFASALDVVHRFSSEIIAKRRDLLKDELDKSSSTADDDG (2)
FVSKKRFAMLDTLIYAE
KDGLIDHIGICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPDKQELCYQEIQEHID (1)
DDLSNLDVGQLNKLKYLEYFMKETTRLFPSVPIMGREAVQETELANGLILPKGAQITIHVFDIHR
NAKYWDSPEEFRPERFLPENVQDRHTYAYVPFSAGQRNCI (1)
GKKYAMQEMKTLMVVLLKQFKVLKAIDPQKIVFHTGITLRTQDKIRVKLVRRT

>4p1ps D. pseudoobscura ortholog of Cyp4p1 Jie Shen 72% to 4P1
MIVFLLTVALCALVLWLYRINKDYYILAFFSRRVRTKDGRPVESILPSPKGRTIFANCFDMYGKDL (1)
AGVFSYSRELSQRLGESYLEYGMGVPLLNIIDAENAENILNHPKLITKSLVYDFLQPALRTGLLTST (1)
EKKWHARRKMLTPTFHFNILGQFQEIFR (2)
AESLKFVQQFQSQDESIVSLSDLIPRFTLNSIC (1)
ETAMGVKLDEMAEKGDRYREGIHMIEMSFIRRLSNPLLWNKTIYNW
FAAKTYDAFLKTVHEFSSEIIAKRRILLEEELEHRRSTQTADDDI (2)
FGSRKKRFAMLDTLICAEKDGLIDHAGICEEVDTLMFEGYDTTSIGLIFSLMNMSLYPEKQELCYKEIEEHID (1)
DSFDNLDNNQLSKLKYLEYFIKETMRLFPSVPIMARQTIQETELANGLILPERSQITIHVFD
VHRNPKYWDSPNEFRPERFLPENCQNRHTYAYIPFSAGQRNCI (1)
GQKFAMQEMKTLIVVLLKKFRILPLIDPKTIVFNVGITLRTQNNIQVKLVRRK

>4p2m AC018129 comp(70087-72192) revised 9/11/2000
MMICLLWISVAILVVIHWIYKVNKDYNILAFFARRVQTKDGKPLDSLVPMIKGRTVFANCFDLLGKDT (1)
DQVFTHLRQLAKNSGDSYLQYSMGFSNFNVIDAHNAANILNHPNLITKGVIYNFLHPFLRTGVLTAT (1)
EKKWHTRRSMLTRTFHLDILNQFQEIFI (2)
AESLKFVSQFQGQNEVVVSLKDRISRFTLNSIC (1)
ETAMGIKLDEMAEKGDRYRANFHIIDEGLTRRIVNPLYWDDCVY
NMFTGHKYNAALKVVHEFSREIIAKRRVLLEEELENRRATQTADDDI (2)
CVIRKKRFAMLDTLICAEKDGLIDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQEIQEHIL (1)
DDLSNLNLSQLSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPKRSQINIHV
FDIHRNPKYWESPEEFRPERFLPQNCLKRHPYAYIPFSAGQRNCI (1)
GQKYAMQEMKTLMVVILKHFKILPVIDPKSIVFQVGITLRFKNKIKVKLVRRNCV

>4P2ps ORTHOLOG FOUND BY B. WU 78% to 4p2
TMIVVLWLTVALCVIVHWLYRVNKDYYIMAFFSRRVRTKDGRPVESIVPMIKGRTVFANCFDLLGKDT (1) 
DQVFTHLRQLAKNSGDSYLQYSMGFSNFNVIDAHNAANILNHPNLITKGVIYNFLHPFLRTGVLTAT (1)
EKKWHARRKMLTRTFHFNILEQFQEIFQ (2)
AESLKFVQQFQSQDESIVSLSDLIPRFTLNSIC (1)
ETAMGVKLDEMAEKGDRYREGIHMIEMSFIRRLSNPLLWNKTIY
NWFAAKTYDAFLKTVHEFSSEIIAKRRILLEEELEHRRLTQTADDDI (2)
FVSRKKRFAMLDTLICAEKDGLIDHAGICEEVDTLMFEGFDTTSIGLIFSLMNMSLYPEKQELCYKELEEHID (1)
DNFDNLDHNQLSKLKYLEYFIKETMRLFPSVPIMARQTIQETELANGLILPERSQIT
IHIFDVHRNPKYWDSPNEFRPERFLPENCQNRHTYAYIPFSAGQRNCI (1)
GQKFAMQEMKTLIVVLLKKFRILPLIDPKTIVFNVGITLRTQNNIQVKLVRRN*

>4p3m AC018129 comp(65426-67385) revised 9/11/2000
MLILWLVGAFIVLIQWIYRLNRDYCILGFFAKRIRTKNGQNPESIAPLVKGSTIFANSFDLYGKDH (1)
SGVFEHSRDCAKKLGKSYAEYAMGTAIYNVIDADSAERVLNDPNLINKGTIYDFLHPFLRTGLLTST (1)
GKKWHARRKMLSPTFHFNILNQFQEIFI (2)
TESLKFLEQFKGNDEAIISLNEVIPRFTLNSIC (1)
ETAMGVKLDEMAEKGDRYRENFRQIEECFIRRMSNPLLWSDTLFKM
FAEKDYASALDVVHGFSSEIIAKRRDQLNDEIDSRGNTQTAEDEL (2)
FTSKKRFAMLDTLILAEKDGLIDHIGICEEVDTLMFEGYDTTSIGLMFGLMNMSLYPEEQEKCYQEIQANID (1)
DELNILNIGQLNKLKNLEYFIKETMRLFPSVPAMGRETTRETELSNGLILPKGSQIFVHVFDI
HRNPEYWDSPEEFRPERFLPENSQNRHTYAYIPFSAGQRNCI (1)
GQKFAMQEMKTLMVALLKQFQILPEIDPKTIVFQTGLTLRTKNQIHVNS

>4P3ps L. Hunt 66% to 4p3
MITLWLTVALCVVIHWLYQVNKDYYILAFFSRRVYTRDDRPVESLVPSPKGRTIFAHCFDLYGKDN (1)
AGVFKFTRDLSKTLGKSYVRYVVGMPIYNVIDAETAEMILTDQKSLIGKGCVYNFLHPALKTGLLTSQ (1)
GDKWHARRRMLTPTFHFNILGQFQEIFQ (2)
AESLKFVQQFQSQDENIVSLSELIPRFTLNTIC (1)
ETAMGVKLDEMADKGDRYRESFHMIEKSFVRRLSNPFLRSTTIYN
LFVAKEYAPFLKVVHDFSSEIIAKRRILLEEELEHRRSTQTADDDI (2)
FVSRHKRFAMLDTLICAEKDGMIDHAGICEEVDTLMFEGYDVSSITLIFTLMNMSLYPDKQELCFKEIQEHIE (1)
DDFSNLDINQMSKLKYLEYFIKETMRLFPPIPLMGRQAVQETELANGLILPSGTQIHIHTF
DIHRNPKHWDSPNEFRPERFLPENSQNRSVYAYIPFSAGQRNCI (1)
AQKFAMQEMKTLMTVILKKFEIQPLVDPNSIVFHVGITLRIKNHIRV

>4s3m AC018488 comp(98620-101060) also AC015418 AC018487
MSTLALVAFVLWAAFLRYLPKILNFLRLQRFAKTLPGPTIGELIANVKKG (1)
EILNWLKELREKHGPVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNYELLEPWLGKGLLTNGGESW
HRRRKLLTPGFHFRILSEFKEPMEENCRILVRRLRTKANGESFDIYPYITLFALDAICET
AMGIKKHAQLQSDSEYVQAVQS (2)
ICRVMHKQSFSFWQRLNVFFKHTKPGKEREAALKVLHD
ETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEGGAELSDTDIREE
VDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASELEGREKESMPYLEAVIKETLR
IYPSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNFPDPERFDPDRFLVNEKQ
MHPFAFAAFSAGPRNCI (1)
GQKFAMLELKTSLAMLLRSYRFLPDKDHQPKPLAELVTKSGNG
IRLRILPRDENGTTA

>4s3ps D. pseudoobscura ortholog of Cyp4s3 L. Yang
MNTWALMAFALWALFLRYLPQILTFLRLQRFAKTLPGPSVSELIANVKKG (1)
EILNWLKELRERHGPVFRIWFGKDLMVMFSDPEDIRQLLGNNSLLYKSRNYALLEPWLGKGLLTNGGESW
HRRRKLLTPGFHFRILSEFKEPMEENCRILVSQLKERANGEAFDIYPYITLFALDAICET
AMGIKKHAQLQSESEYVKAVQT (2)
ICRVMHKQSFSFWQRLNIFFKYTQAGQERDGALRVLHD
ETNRVIRLRREQLVKERQLQQRTEAAQDDVGSKRRLAFLDMLLLTQLEGGDELSDRDIRE
EVDTFMFEGHDTTSSAIAFALSLLSKHSEVQQRAYEEARDLEGREKESMPYLEAIIKETL
RLYPSVPFFSRKVFEDIQVGKHTIPKGASVNCLIYMLHRDCNNFPDPERFDPDRFYLNEK
QMHPFAFAAFSAGPRNCI (1)
GQKFAMLELKCSLSSLLRSFQFMPDEDHQPIPLAELVMKSGNGVRLRIQPRSQH*

>4aa1m AC020355 comp(15477-16779) and AC007579 comp(38212-38842)
MHLRLLSPPQLERTTNLELCSILILLVISLSIYTFYATLNTYLRSVLLSLRLTGPPSLPFLGNCMLVTDKD (1)
LMRRCAGKAFDLYGSLVRIWVLLFPFFAVLEPEDLQVILSSKKHTNKVF
FYRLMHNFLGDGLITSSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEAV
GTEINIAKYVNNCVLDILN (1)
EAVLGVPIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLL
DGIYHWTKMANDELNQKKRLNDFTRKMIQRRRQIQNNNNGNSERKCLLDHMIEISESNRD
FTEEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMT
DLHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIY
PDPEKFQPERFSPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPV
TGKTTIAATFRITLRASGGLWVRLKERDHPLIAH

>4aa1ps  S. Yu 79% 
MQFYTRMTV 
PQLERATRTELCSILALLVISLSIYLFYAHLDTYLRSVILSLRLSGPPTLPILGNCLLIKDKD (1)
LMRNQAAKAFDLYGSLVRIWVLFFPFFVVLQPEDLQVILSSQKHTNKVFIYQLMHNFL
GDGLITSSGLKWSTHRRLIQPAFHLSLLEKFIGTFVDASQSLYESVGASAVGTDINIVSI
VNNCVVDILN (1)
EAVLGVPIKKKGLDLVKIDESPFRQGKLMIPTRFSHPWLLFDGIYHWTKL
ANDELNQKKRLHDFTRQMIKIRREILANTGNNNAERKCLLDYMIEISESNPDFTEQDIVN
EACTFMLAGQDSVGGAVAFTIFLLAQNAECQEQCHEELERIFDYSDRAPTMSDLREMRYL
EMCIKEALRLYPTVPLIARKLGEEVRLSDHTLPAGSNIFICPYATHRLNNIYPEPEKFNP
ERFSPENSKDRHPYAFIPFSAGPRYCIGNRFAIMEMKTIVSRLLRSFQLLPVAGKTTFDV
SYRITLRASGGLWVRLKPRDHPISQTRDSDCFGL*

>4ac1m AC017771 comp(24745-26507)
MWIALLGIPILLAVLTLLLKHINKTYFILSLTKRVRTEDGSPLESKVAIMPGKTRFGNNLDILNFTP (1)
ASVFNFVRESTAKAKGQNYLWYFLYAPMYNVVRPEEAEEVFQSTKLITKNVVYELIRPFLGDGLLIST (1)
DHKWHSRRKALTPAFHFNVLQSFLGIFK (2)
EECKKFLNVLEKNLDAELELNQVIPPFTLNNIC (1)
ETALGVKLDDMSEGNEYRKAIHAIEEVLIQRVCNPLMYYNWYFF
VYGDYRKHLQNLRIVHDFSSRIIERKRQQFQQKQLGEVDEFGRKQRYAMLDTLLAAEADG
QIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEVENLPEDSDDISMF
QFNKLVYLECVIKESLRMFPSVPFIGRQCVEETVVNGMVMPKDTQISIHIYDIMRDPRHF
PKPDLFQPDRFLPENTVNRHPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFKLLPA
TQLEDLTFENGIVLRTQENIKVKLSKRVK*

>4AC1ps D. pseudoobscura Y. Zhuang deletion at heme 82%
MLIALLGTPLLLLGVWLLLQRLNRTYFILSLTRRVRTEDGSPLESKVAVMPGTTRFGNNLDVLNCTP (1)
SSLFNFLRDSAAKAQGRNFLWYFLFAPMYNVIRAEEAEEIFQSTKLITKNVIYELLRPFLGEGLLIST(1)
DQKWHSRRKALTPAFHFNVLQSFLAIFK(2)
EECNKLIKVLDKKVDGELDLNQVIPQFTLNNIC (1)
ETALGVKLDDMSEGNQYRRAIHAIEEVLIQRVCNPLMFYNW
YFFLIGDYRKQVQNLRIVHDFSSRIIERKRQQFKRKQLGVVDDFGKKQRYAMLDTLLAAE
AEGQIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEEVQERCLEEVSTLPEDTDSI
SVFQFNELVFLECVIKESLRMFPSVPFIGRTCVEECVVNGLILPKDTQISIHIYDIMRDP
RHFPNPHEFQPERFLPENTVDRHPFAFVP 
EIKVLLAAVLRNFRILPVTRLEDLTFENGIVMRTQQNVKVKLVRR*

>4ac2m AC017771 comp(22220-24109) revised 9/8/2000
MFLEVLFAAPLVIFIFRKLWAHLNRTYFILSLCKRIRTEDGSLLESKIYVAPSKTRFGNNFDLVNFTS (1)
ESIFNFMRDASAKAKGRNYLWYFFHAPMYNIVRAEEAEEILQSSKLITKNMIYELLKPFLGEGLLIST (1)
DQKWHSRRKALTPAFHFKVLQSFLIIFK (2) 
EECNKLVKVLHQSVNMELELNQVIPQFTLNNVC (1)
ETALGVKLDDLSEGIRYRQSIHAIEEVMQQRLCNPFFYNIVYF
FLFGDYRKQVNNLKIAHEFSSNIIEKRRSLFKSNQLGQEDEFGKKQRYAMLDTLLAAEAD
GQIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEIKYLPDDSDDISV
FQFNELVYMECVIKESLRLFPSVPFIGRRCVEEGVVNGLIMPKNTQINIHLYEIMRDARH
FSNPKMFQPDRFFPENTVNRHPFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNFKILP
VTLLDDLTFENGIVLRTKQNIKVKLVHRENK

>4ac2ps Contig3635_Contig7816.24 75% to 4ac2 74% to 4ac1
MFELLLGVPLIVLLCCVLLRRLNRKYFVLSLCKRLQAEDGSPLESKIAVMPGRTRFGNNFDLLNFTP (1)
STVFNFMRDSCANARGRNYLWYFFGSPMYNVIRAEEAEEIFQSTKLLTKNVVYDLLRPFLGEGLLTST (1)
DQKWHARRKALTPAFHFNVLQSFLAIFK (2)
EECHKLVKVLHESVESEALVLNQVIPQFTLNNIC (1)
ETALGVKLDDMAEGFQYRESIHAIEAVILQRICNPFLYNSLYFYLY
GDYRKHIDSLKIAHDFSSSIIERRRRDIKRKELGVVDDFGKKQRYAMLDT
LLAAEADGQIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLSLHKDVQER
CLEEVSALPEDTDSISVFQFNELVFLECVIKESLRMFPSVPFIGRQCTEE
CVVNGLVMPKDTHINIHIYDIMRDPRHFPNPNAFQPERFLPENTVDRHPF
AFVPFSAGQRNCIGQKFAILEIKVLLAAVLRNFKILPDTRFEDLTIENGI
VLRTQQKVKVKLVQRVG*

>4ac3m FROM DROSOPHILA 
MWIALLGSSLLIGALWLLLRQLNKTYFILSLCKRVRTADGSPLESKVFVVPGKTRFGNNLDLLNLTP (1) 
ANIFSYIRESTAKANGQNYIWNFLFAPEYNIVRAEDAEEIFQSTKITTKNMSYELIRPFLGDGLLISI (1) 
DQKWHTRRKTLTPAFHFNILQSFLSIFK (2) 
EESKKFIKILDKNVGFELELNQIIPQFTLNNIC (1)
ETALGVKLDDMSEGNEYRKAIHDFEIVFNQRMCNPLMFFNWYFF
LFGDYKKYSRILRTIHGFSSGIIQRKRQQFKQKQLGQVDEFGKKQRYAMLDTLLAAEAEG
KIDHQGICDEVNTFMFGGYDTTSTSLIFTLLLLALHADVQERCYEELQDLPEDIDEVSMF
QFNELIHLECVIKESLRLFPSAPIIGRTCIEESVMNGLVLPKNAQISIHIYDIMRDARHF
PKPNQFLPERFLPENSVNRHPFAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNFKLLPA
TQLEDLTFENGIVLRTQQNIKVKFEARVK

>4ad1m AC020402 comp(36565-39829)
MFLIAIAIILATILVFKGVRIFNYIDHMAGIMEMIPGPTPYPFVGNLFQFGLKPA (1)
EYPKKVLQYCRKYDFQGFRSLVFLQYHMMLSDPAEIQ (0)
NILSSSSLLYKEHLYSFLRPWLGDGLLTSSGARWLKHQKLYAPAFERS
AIEGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIVC (1)
ENATGQDSSSLNGETSDLHGAIKD (2)
LCDVVQERTFSIVKRFDALFRLTSYYMKQRRALSLLRSELNR (0)
IISQRRHQLAAENTCQQGQPINKPFLDVLLTAKLDGKVLKEREIIEEVSTFIFT (0)
GHDPIAAAISFTLYTLSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPLIARTNRNPIDI (1)
NGTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERFENPTGNVGIEAFKSVPFSAGPRRCI (1)
AEKFAMYQMKALLSQLLRRFEILPAVDGLPPGINDHSREDCVPQSEYDPVLNIRVTLKSENGIQIRLRKR

>4AD1ps of D. pseudoobscura R. Aziz 87%
MFLIAIAIILATILVFKGVKIFNYIDHMAGIMEMIPGPTPYPFVGNIFQFGLKPA (1)
EYPKKVLQYCRKYDFQGFRSLVFLQYHMMLSDPAEIQ (0)
NILSSSSLLYKEHLYSFLRPWLGDGLLTSSGARWLKHQKLYMPAFERSAIEGYLRVVHR
TGGKFVQKLNELTETLEVFDAQELVAKCTLDIVC (1)
ENATGLVSNSLNDEPSDLHGAIKD (2)
LCDVVQERTFSIVKRFDALFRLTSYYMKQRRALSLLRREIYR (0)
IITQRRQQLADENTCGERTKKINKPFLDVLLAAKLDGRALKEREIIEEISTFIFA (0)
GHDPVAAAISFTLYTLSRHTEIQQRVFEEQQRIFGQDLTAEADIGRLDQM
RYLELVIRETLRLYPSVPLIARTNRKPIDI (1)
NGTKVAKRTTVIMCLIAMGYNEKYFEEPCVFRPERFETAGADVGIEAFKSVPFSAGPRRCI (1)
AERFAMYQLKALLSQLLRNFEILPPVNGLSSGINDHSQVECVPQSEYDPVLNIRVTLKSENGIQIRLGKRAFVE*

>4ae1m old 4e4 AL009194 16210-17867
MLVVLLVALLVTRLVASLFRLALKELRHPLQGVVPSVSRVPLLGAAWQMRSFQPD (1)
NLHDKFAEYVKRFGRSFMGTVLGHVVMVTAEPRHIDALLQGQHQLKKGTMYFALRGWLGDGLLLS
RGKEWHTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRTLSYGNEVVNIYPLVGLAAL
DIITETAMGVNVDAQGADSEVVHAVKD (2)
LTNILATRFMRPHLLFPHLFRLCWPSGFRKQQA
GVICLHEFTNGIIEQRRRLLAREANQDKPTKPHALLDTLLRATVDGQPLTDKQIRDEVNT
FIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEELRMHYGQDLFRGVILSDFATLPYLSCV
VKESLRLYPPIPAVARCLEKDLVI (1)
DEGYIPVGTNVVVLLWQLLRDEAIFTDPLVFQPERHLGEEAPRLSPYSYIPFSAGPRNCIG
QKFALLEMKTMVTKVIRHYQLLPMGADVEPSIKIVLRSKSGVNVGLRPRLY*

>4AE1ps ortholog Stephanie Nance 71%
MLMALLLTMALTLIVAWLLQLALREMRHPLRGFVPSVSRVPLVGAAWQMRSFQPD (1)
NLHEKFAEYVERFGRSFMASVCGQVIMVTAEPSHVDALLHSQKQLRKSSIYGALRGWLGNGLLLS
QGEQWHGMRKIITPTFHFSILEEFVEVFDKQSQLLVERLQPLSNGGMVAINIYPYVGLAA
LDIITETAMGVCVNAQLDADSAVVQAVKA (2)
VTNTLATRFMRPHLLPPLLFRLCWPSGFRKQ
QEGIKCLHLFTNSIIEQRRQLLRRENAPGEPVARDRRNALLDTLLRATVDGQPLTDKQIR
DEVNTFIFEGHDTTTSAISFCLYLLSRHAAVQERLFDEVKGHFGRELDRCVVYSDFAALP
FLNCVVREALRLYPPIPALGRCLETDLAV (1)
EGGRIPAGTNVILLLWQLLRDEMLFADPLIFRPERHLSNKATSKKGAYSNIPFSAGPRNCIG
QKFAMFEVKTMIIKMLRNFILLPIGPDVEPSIKIVLRSRNGVHFGLRPRVY*

>6a2m AC007549 comp(100072-101661)
MFVLIYLLIAISSLLAYLYHRNFNYWNRRGVPHDAPHPLYGNMVGFRKNRVMHDFFYDYY
NKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQHLFN
LDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMA
RFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMR
MMPEDVHQFFMRLVNDTIALRERENFKRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGEL
AAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVIS (1)
ETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNP
ETFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTT
EIPLKYSPMSIVLGTVGGIYLRVERI

>6a2ps orth found byu F. Cao
MLILIYLVIAVGSLVAYLLHRNFQYWKRKGVPHDPPHPFYGNLVGFRKNRVIHDIFYDYY
NKFRTSGSPFVGFFFLQKPAAFIVDTKLAKNILIKDFSNFADRGQFHNERDDPLTQHLFN
LDGKRWKELRQRLSPTFTSGKMKLMFPTVIKVSEEFASVMEEQVPPTQGGAIIEIKEMMA
RFTTDVIGTCAFGIECNTLRTPVTDFRTMGQKAFTELRHGQLLTFFIFSFPKLARRLRMR
IMPEDVHQFFMRLVNDTVAVREKENFKRHDFMDMLIEIKQKGSVTLENGEVMKAMDIGEL
AAQVFVFYLAGFETSSSTMSYCFYELAQHQDIQDKLRS EVLTVLAEHDGKLTYECVKEMRYLDQVFS (1)
ETLRLYTLVPHLERRALSDYVVPGHPDLVIEKDTQIIIPACAYHRDENLYPDP
LRFDPDRFSAEQVAARDSVEWLPFGDGPRNCIGMRFGQMQARIGMAQLLSRFKLSLCDKT
EIPLKYEPKSFVLGSIGGIYLRLERI

>6a8m AC020447 comp(122688-124264)
MALTYILFQVAVALLAILTYYIHRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQ
DHYNKFRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAH
LFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVA
RFTVDVIGTCAFGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMV
RTAPHIQEFYSRIVTETVAVREKEHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEV
LAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLD (1)
ETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEP
FEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKT
PNPLVYDPKSFVLGVKDGIYLKVETV

>6a8ps D. pseudoobscura ortholog of 6a8 76% found by K. Cheng and Marie van der Merwe
MGVTYVLLQVAVALLAIVTYYVYRRLSYFKSRGIPHDTPHLILGNMQGVFTKRNVHEILK
KYYEKYRESKVPFVGFYFFQKPSAFILDLDLAKHILIKDFSNFSDKGLFYNEKDDPISAH
LFNLDGPQWKVLRNKLTSTFTAGKMKFMYPTVVSVAEEFIDVMHEKMKQNSVLEIRELMA
RFTVDVIGTCAFGIKCNSLRDENAEFLRFGKRTFVDKRHGSFLTGFMTSYPKLARRLRLV
RTPTHIRNFYERIVHETVAMREKENIKRNDFMDLLIDMKNQKVKLENGDLVDGLTIDEIL
AQAFVFLIAGFETSSSTMGYALYELAKQPHIQDKVRAEVEEVLEQHEQKFTYESTKDLKYLEQVIF (1)
ETLRLHTIVPHLDRMAHKRYVVPGHPNFVIEAGQSVIIPASAIHVDPNIYPDPY
KFRPERFSPEESAKRNSLAWLPFGDGPRNCIGLRFGKMQTTIGLALLIKNFKFSTCPKTP
DTLSYSPKSFVLAVDGIHLKVEAV*

>6a9m AC020447 comp(115043-116610)
MGVYSVLLAIVVVLVGYLLLKWRRALHYWQNLDIPCEEPHILMGSLTGVQTSRSFSAIWM
DYYNKFRGTGPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYHNTEDDPLSGQL
FLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDILAR
FTTDVIGTCAFGIECSSLKDPEAEFRVMGRRAIFEQRHGPIGIAFINSFQNLARRLHMKI
TLEEAEHFFLRIVRETVAFREKNNIRRNDFMDQLIDLKNSPLTKSESGESVNLTIEEMAA
QAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEITYESMKDMVYLDQVIS (1)
ETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNT
FNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSVCEQTTI
PIVYSKKTFLISSETGIFLKVERV

>6a13m AC020451 3757-5238 also AC007085 126189-124714 no introns
MLTLLVLVFTVGLLLYVKLRWHYSYWSRRGVAGERPVYFRGNMSGLGRDLHWTDINLRIY
RKFRGVERYCGYFTFMTKSLFIMDLELIRDIMIRDFSSFADRGLFHNVRDDPLTGNLLFL
DGPEWRWLRQNLTQVFTSGKMKFMFPNMVEVGEKLTQACRLQVGEIEAKDLCARFTTDVI
GSCAFGLECNSLQDPESQFRRMGRSVTQEPLHSVLVQAFMFAQPELARKLRFRLFRPEVS
EFFLDTVRQTLDYRRRENIHRNDLIQLLMELGEEGVKDALSFEQIAAQALVFFLAGFDTS
STTMSFCLYELALNPDVQERLRVEVLAVLKRNNQKLTYDSVQEMPYLDQVVAETLRKYPI
LPHLLRRSTKEYQIPNSNLILEPGSKIIIPVHSIHHDPELYPDPEKFDPSRFEPEEIKAR
HPFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRDFKFSRSEKTQIPLKFSSRNFLISTQ
EGVHLRMEGLERP

>6A13ps ortholog Contig3531_Contig5436.180 77% to 6A13 no introns
MWTLLALVLVAGALIYSRLLEHYDYWRRKGVAGEKPVLFLGNMSGLGKGL
HWTDINRRIYEKFSKTERFCGYFTFFSKAFFVMDLELIKKITISDFSSFA
DRGLFHNVKDDPLTGNLLFLDGPEWRWLRQNLTQVFTSGKMKFMFPTMLS
VGEKLTQACELQVGEIEAKDLCARFSTDVIGSCAFGLECNSLNDPNSEFR
RMGRSVTTNPLHTGMVQGFMFAQPKLARMLHMRLFRPEVSEFFLETVRQT
LAYRKRENVQRSDLIQLLMDLGEEGTKDGLSFEQIAAQAMVFFLAGFDTS
STTMSFCLYELALNPDVQDRLRSEILEVLAKNNHQLTYESIQEMPYLDQV
VAETLRKYPILPHIVRQTTKKYDVPDSRLTLEPGMRVMIPVHSIQHDPEL
YPEPENFDPSRFEPDQVKARHPMAYLPFGEGPRNCIGERFGKMQVKIGIA
YILRDFQFRQSERTQIPLKFSSRTFLIGTQEGIHLIMEKLAAP*

>6a14m AC007085 33266-34850 frameshift at amino acid 73 possible pseudogene
MLFTIALVGVVLGLAYSLHIKIFSYWKRKGVPHETPLPIVGNMRGIVKKYHFRDINQRIY
KKFKGQGPIAGMY 
TFFKRTALITDLDFIKQVMIKDFSYFQDRGAFTNPRDDPLTGHLFAL
EGEEWRAMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGNVEIKDLCA
RFTTDVIGSCAFGLECNSLQDPSAEFRQKGREIFTRRRHSTLVQSFIFTNARLARKLRIK
VLPDDLTQFFMSTVKNTVDYRLKNGIKRNDFIEQMIELRAEDQEAAKKGQGIDLSHGLTL
EQMAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVL
AQMTYLDQVLS (1)
ETLRKHPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIY
PEPEKFDPSRFDPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVS
NRTDVPLIFSKKSFLLTTNDGIYLKVERV

>6A14ps ortholog Contig3531_Contig5436.179 no frameshift as in D. melanogaster
MALALAYNFYRNTYSYWERKGVPNERPLPLIGNVKGIGTKYHFRDINQRI
YDKFKGVAPFAGMFTFFKRSALIIDLDLIKQVLIKDFQYFQDRGVFNNVR
DDPLTGHLLTLEGDEWRSMRQKLTPVFTSGKIKHMSGVVVEVGHRLAAAM
DKAVSAAKVDDGDVEIKDICARFTTDVIGTCAFGLECHSLSDPKAEFRSK
GRMIFEKPRHSPIVQFFVFTNAKLAKKLRMKLLPDDVSEFFMNAVKNTVD
YRMKNGIKRNDFLDELIELRAENQEAAKHGKVIDLSHGLTIEQMAAQAFV
FFLAGFETSSSTMAYCLYELAQHPDIQRRVREEIDAVLKNVEGGEITYDA
LAEMNYLEKVLA (1)
ETLRKHPIVPQLIREANQNYKVPNTDITIDKGTTVLIP
VHSIHHDPEIYPQPESFAPSRFEADQVKSRHPMAYLPFGDGPRNCIGLRF
GKIQAKIGLVSLLRRFKFGISKRTEIPLILDTRSFPLTTKNGIHLRVERI*

>6a15pm this is a pseudogene on AC020451 2595-3373 with in frame 
AFTVTNSKLAKKLKMKILRDDLTDFFLSVVKPALSGMTLWTSPPSGGRSSRQGGSKFDLS
HNWTLEQMAAQAIVFFLAGFETSSSTMSSCKYELALQPEI*NQIRDEIERVLEGNAITYD
ALAKINYPEQVLS (1)
ETLRKH
QLIKFLLETQESFRVRNTELIVEKGTSLLIPVHSVHYDPHLYPHPKLFDSSR
LKAYKSNSRHPFAYLPFGTFGPRSCIGLRFGKMQAKIGIVSLCQRFKFGDSDLTDIPL

>6a16m AC004721 comp(2956-5070) note 1 extra intron 
MDFTLLLLTSLLSFLLGYLRYRFTYWELRGIPQLRPHFLFGHFFRLQSVHYSELLQETYD
AFRGSAKVAGTYVFLRPMAVVLDLDLVKAVLIRDFNNFVDRRSFHGDPLTANLFNLQGEE
WRNLRTKLSPTFTSGKMKYMFGTVSTVAQQLGGTFDELVGSQ (0)
GAVLELHDLMARYTTDVI
GSCAFGTECSSLREPQAEFRQVGRRIFRNSNRSIRWRIFKMTYLSSLAKLGLPVRILHPD
ITKFFNRIVRETVELRERENIRRNDFMDLLLDLRR
KGLTMEQMAAQAFVFFVAGFETSSS
NMSYALFELAKNQDVQQKLRMEINDSIGKHGKLTYEAMMEMPYLDQTIT (1)
ETLRKYPALSS
LTRLASEDYEIPSPDGGDPVVLEKGTSVHIPVLAIHYDPEVYPEPHEFRPERFAPDACRE
RHPTAFLGFGDGPRNCIGLRFGRMQVKVGLITLLRRFRFSLPPGSPTQLKVTKRNLILLP
SDGVRLQVDPVESRLM

>6A16ps ortholog Contig4092_Contig573.216 61% to 6A16
MGFVLILLTSLLSGVLGYLRCKYNYWQINGVKQLRAHFLFGHFFKMKSVR
LTELLQETYDAFKGSALVAGTYVYLRPIAVILDLDLAKTILDKDFDKFVD
RRNFHKEPLMDNLFNAQGEEWCTLRKKLTPMFSSGNVKCIFGTITEVARN
LEESFQELVGTQGGVLDVHDLLDRFSMDASATCAFGIQCSSLKDPQVEFR
VHGRKIFHHSGDGIRWRIFKFLYWSVLAKLKLSVRFYDKIIADFFTRIVR
EKLELRQDLRHNIKRNDFLELLMASKDDNELTLEQLTAHAFDFFVSGYET
SSSTMSCALFELAKHPSVQQKLRNEITGILHKHAPNLTYEAVQEMRYLDQTIT (1)
ETLRKYPALASLTRIAAEDYTVPTASGDIPLVLDKGTIVHIPVRAIH
YDSEIYPEPTIFRPERFETSTCLQRHSMAFLGFGDGPRHCIGQQFGRMQI
KIGLIALLTKYQFSSVPGFPDELPISKGNVILRPRQGVLLKVHRVPE

>6a17m AC020447 109264-110826
MLLLALIVVILSLLVFAARRRHGYWQRRGIPHDEVHPLFGNIKDWPNKRHIAEIFRDYYF
KYKNSDYPFAGFFFFFTRTAVVTDMELLKRVLIKDFNHFENRGVFYNEIDDPLSATLFSI
EGQKWRHLRHKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRSKTAADRGQVLEVVDLVARY
TADVIGNCAFGLNCNSLYDPKAEFVSIGKRAITEHRYGNMLDIFLFGFPKLSRRLRLKLN
IQEAEDFYTKIVRETIDYRLRTKEKRNDFMDSLIEMYKNEQSGNSEDGLTFNELLAQAFI
FFVAGFETSSTTMGFALYELARNQDVQDKLREEIGNVFGKHNKEFTYEGIKEMKYLEQVVM (1)
ETLRKYPVLAHLTRMTDTDFSPEDPKYFIAKGTIVVIPALGIHYDPDIYPEPEIFKPER
FTDEEIAARPSCTWLPFGEGPRNCIGLRFGMMQTCVGLAYLIRGYKFSVSPETQIPMKIV
VKNILISAENGIHLKVEKLAK

>6A17ps Ortholog of D. pseudoobscura JUN SHEN
MSLVLALIAIVVSLVLFAARRRHGYWQRRGIPHDVPHPLFGNIGDWPKKRQIAVIFRDYY
RKYKNANYPFAGFYFFFTRSAVVTDLDLVKRVLIKDFNHFENRGIFYNEIDDPLSATVFS
IEGQKWRHLRHKLTPTFTSGKMKHMFPIVVKVGEEMDKVFSNKVGDGKVLEIVDLVARYT
ADVIGNCAFGLNCNSQQNPNADFVTFGKRALRERRYKGLLDFFIFGFPKLSRSLRLKLNV
QEVEDFYTKIVRDTIDYRLKTKEKRNDFMDSLIEMYQKEQEGNSDEGLTFNEILAQAFIF
FVAGFETSSTTMGFALYELAQNQDTQDKLRNEINDVLAKHNNQFTYEGIKEMKYLEQVVM (1)
ETLRKYPALGHLTRKTRLDFSPEDPKNFIAKGTTVVIPALGIHYDPDIYPEPEKFKPERF
TEEAIASRPACAWLPFGEGPRNCIGLRFGLMQTCVGLAYLIKGYRFSVAPETQIPIKFVL
KSFLLSAENGIYLKVETVSK*

>6a18m AC008285 85740-87319
MQLTYFLFQVAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEIHQ
EYYNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAH
LFNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVA
RFTVDVIGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLARRLGLC
RNTAQIQEFYQRIVKETVTLREKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEI
VAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVIN (1)
ETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEP
NEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSAT
PDPLTFDPHSAILLGIKGGIQLKVEAI

>6a19m AC020447 113084-114646
MAILLGLVVGVLTLVAWWVLQNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGILKRTY
LKFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPLTNNLA
TIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSR
FTSDVIGICAFGLKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQF
LLPSVQKFYMKIVQDTIDYRMKRKVTRNDFMDTLIDMKQQYDKGDKENGLAFNEVAAQAF
VFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVIN (1)
ESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPE
RFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMKY
TINNLLLGSEGGIHLNITKVVRD*

>6a20ps Contig3531_Contig5436.184 71% to 6A20 65% to 6A19 
MAIIIVLLVGVISLAVWWVHQNFSYWKRRGIPHDPPNIPKGNTSELMKTR
QIADLFRETYFKYKGKTDGPFVGFYLYLKKIAIVTDIDFVKTVLIREFDK
FHDRGLFHNEKDDPLTNHLVAIEGQKWRQLRQKMTPTFTSGKMKIMFPTV
LEIGNEMIRVFAEKIGPQPLNVADLVSRFSADVIGSCAFGLECNSLRNPN
AEFVTMGKAAITERRYGKTADLFFFGAPKLAAKLRMKETVQKVEDFYMKI
VRETVDYRLKNNVKRNDFMDMLIDMKINYDKGNKQDGISFNELAAQAFIF
FLAGFDTSSTSLGFALHELAVNQDIQDKLRTEIDTVMAKHNGQLNYDSMR
ELTYLDKVID (1)
ETFRKNPVVGHLIRICTQRYEHPNGKYFIEPGTGVVIPTL
GIHHDPEFYPEPEKFKPERFDEDQVLQRPPCTFLPFGDGPRTCIGLRFGR
MQIVVGLALLIHNFKFEVHPTKTTVPLKFKVTDVLLCSEGGVHLNVSKVPR*

>6a20m AC020447 117416-119045 this seq has a frame shift at NKLR-NKTD
MAVMIVLLIGVITFVAWYVHQHFNYWKRRGIPHDEPKIPYGNTSELMKTVHFADIFKRTY
NKLR 
NKTDGPFVGFYMYFKRMVVVTDIDFAKTVLIREFDKFHDRGVFHNERDDPLSANLV
NIDGQKWKTLRQKLTPTFTSGKMKTMFPTILTVGDELIRVFGETASADSDSMEITNVVAR
FTADVIGSCAFGLDCHSLSDPKAKFVQMGTTAITERRHGKSMDLLLFGAPELAAKLRMKA
TVQEVEDFYMNIIRDTVDYRVKNNVKRHDFVDMLIEMKLKFDNGDKENGLTFNEIAAQAF
IFFLAGFETSSTTMGFALYELACHQDIQDKLRTEINTVLKQHNGKLDYDSMREMTYLEKVID (1)
ETMRKRPVVGHLIRVATQHYQHTNPKYNIEKGTGVIVPTLAIHHDPEFYPEPEKFIPE
RFDEDQVQQRPACTFLPFGDGPRNCIGLRFGRMQVIVGMALLIHNFKFEFHPTKTVVPLE
YRTDDFLLSSKGGIHLKVTRV

>6a21m AC020447 comp(120585-122149)
MSVGTVLLTALLALVGYLLMKWRSTMRHWQDLGIPCEEPHILMGSMKGVRTARSFNEIWT
SYYNKFRGSGPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDDPLSGQL
FLLDGQKWRTMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPVVEVRELLAR
FTTDVIGTCAFGIECSSLKDPDAEFREMGRRSLTEQRLGPVGIGFVNSFPNLARRLHMKM
TAEPIERFFMRIVRETVAFREQNNIRRNDFMDQLIDLKNKPLMVSQSGESVNLTIEEIAA
QAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCNGELNYESMKDLVYL
DQVVS (1)
ETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNT
FNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSVCEKTTI
PMTYNKEMFLIASNSGIYLKAERV

>6a21ps Contig3531_Contig5436.185 78% TO 6A21 
MAVGVGALLLWTLVALVVYLLLKWLLGRQYWQNLGIPCEEPHWLLGSMWG
LRTTRTFNDVWTDYYKKYRLSGPFAGFYWFQRPAVFVLEPSLAKLILIKE
FNKFTDRGFFHNPEDDPLSGQLFLLDGHKWKSMRHKLSSTFTSGKMKYMF
PTVVKVSHEFTEVFGQMADKSPIVEVRELLARFTTDVIGTCAFGIDCSSL
KDPDAEFRKMGRRALTENRHGSLGIAFLNSFPKLSRKLHLKMTAEPIEQF
FMRIVKETVKFREQNQIRRNDFMDQLIDLKNNQIIKTESGDNINLTIEEI
AAQAFVFFAAGFETSSTTMGFALYELAQHPDIQQRVREECQEVIQKYGGE
LTYESMKELVYLDQVIS (1)
ETLRLYTVLPVLNRECLEDFVVPDNPKYVIKKG
MPILIPAGAMHRDERFYPNPDAFNPDNFSPERVKNRDSVEWLPFGDGPRN
CIGMRFGQMQARIGMAMLLKDFKFSVCDETAFPMKYDLESFLIASKTGIS
LRVERV

>6a22m AC020447 106987-108653
MLDVVALLLIALAVGFWFVRTRYSYWTRRGIGSEPARFPVGNMEGFRKNKHFIDIVTPIY
EKFKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHLFR
IDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDLMAR
YTSDVIGRCAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARFLRMRQ
IHQDITDFYVGIVRETVKQREEQGIVRSDFMNLLIEMKQRGELTIEEMAAQAFIFFAAGF
DTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIA (1)
ETLRKYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQ
LAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEFLKSNIL
LCPANGIYLKVQQLSQMSS

>6A22ps ortholog Contig3531_Contig5436.181 82% to 6A22
MLDVIALLLITLAIGFWYVRTRLSYWARRGIGHVRPTFPMGNMDGLRRTK
HFKDIVTPLYERFKDSGAPFAGIYMMLRPVVLVLDLDLAKEVLIRDFANF
EDRGMYHNERDDPLTGHLFRIDGPKWRPLRHKMSPTFTSGKMKFMFPTIC
EVGVDLAEVCGELAANAICGILEISDIMGRYTSDVIGRCVFGLECNGLRN
PEAQFAVMGRRAFTERRHNQLIDGFIESFPDLARRLRMCQIHQDITDFYL
GIVKETVKLREEQGIVRNDFMNLLIEMKHRGELTLEEMAAQAFIFFAAGF
DTSASTLGFALFELARQPQLQDKLRQEIDAALQLHQGQFTYDSMQELRYMELVIA (1)
ETLRKYPPLPHLTRISKNLYTAKGNRHFYIEPGQMLLIPVYGIHH
DPAIYPEPHKFIPERFMGDQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTS
IALVNLLRRFHFSVCPRTESKIEFVKSNLLLCPANGIYLKVQEISKLK

>6a23m AC020447 111145-112718
MSLLLTLIALLVSLLLFMARRRH GYWQRRGIPHDVPHPIYGNMKDWPKKRHIAMIFRDYY
TKYKRSVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDPLS ATLFS
IEGQKWRHLRHKLTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTT GEGQVLEIVDLVAR
YTADVIGNCAFGLNCNSLQNPNAEFVTIGKRAIIERRYGGLLDFLIFGFPKLSRRLRLKL
NVQDVEDFYTSIVRNTIDYRLRTNEKRHDFMDSLIEMYEKEQAGNTEDGLSFNEILAQAF
IFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVM (1)
ETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYPEPEKFKPE
RFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVSTETQIPMKF
VVKSILLSAENGIHLKVEKLSK

>6A23ps ortholog Contig3531_Contig5436.183 76% to 6A23
MSLVLALIAIVVSLVLFAARRRHE
YWQNLGIPCEEPHWLLGSMWGLRTTRTFNDVWTDYYKKYRLSGPFAGFYWFQRPAVFVLE
PSLAKLILIKEFNKFTDRGFFHNPEDDPLS
ATVFSMKGQKWRHLRHKLTPTFTSGKMKHMFPIVVKVGEEMDKVFSNKV
GDGKVLEIVDLVARYTADVIGNCAFGL
NCNSQQNPNADFVTFGKRAIGERRYWGLLDFFIFGFPKLSRSLRLKLNVQ
EVEDFYTKIVRDTIDYRLKTKEKRNDFMDSLIEMYQKEQEGNSDEGLTFN
EILAQAFIFFVAGFETSSTTMGFALYELAQNQDTQDKLRNEINDVLAKHN
NQFTYEGIKEMKYLEQVVM (1)
ETLRKYPVLAHLTRKTQADFSPEDPKTFIAK
GTVVVIPALGIHYDPDIYPEPEKFKPERFTEEAIASRPACTWLPFGEGPR
NCIGLRFGIMQTCVGLAYLIKGYRFSVAPETQIPMKLILKSILLSAENGI
YLKVKKVSK*

>6d2m AC020206 comp(66328-68065) also AC008350
MWTILLTILIAGLLYRYVKRHYTHWQRLGVDEEPAKIPFGVMDTVMKQERSLGMALADIY
ARHEGKIVGIYMLNKRSILIRDAQLARQIMTSDFASFHDRGVYVDEDKDPLSANLFNLRG
ASWRNLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTTYAVDI
IGSVIFGLEIDSFRNPKNEFREISSSTSRDESLLLKIHNMSMFICPP (2) 
IAKLMNRLGYESR
ILTSLRDMMKRTIEFREEHNVVRKDMLQLLIRLRNTGKIGEDDDQVWDMETAQEQLKSMS
IEKIAAQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFT
YEAVQDLKFLDICIM (1)
ETIRKYPGLPFLNRECTEDYPVPGTNHIIAKGTPILISLFGMQRD
PVYFPNPNGYDPHRFDSNNMNYDQAAYMPFGEGPRHCI (1)
ALRMGKVNSKVAVAKILANFDL
VQSPRKEVEFRFDAAPVLVTKEPLKLRLTKRK

>6d2ps Drosophila pseudoobscura ortholog of 6d2 Nawazi 80%
MWAILTLLTLALGLLYQFVRRHYSSWQRLGVDEETPKIPMGILDTVMKQEMSLGMVLSDI
YKRHKGKIVGIYMMNKRSILVRDAQLARQIMTSDFASFHDRGVYVDEKNDPLSANLFNLR
GASWRNLRKKMTPSFSSGKIKGMFGTIDDVGDKMVQHLKGVLERAGADNEIDIKEMMTTY
AVDIIGSVIFGLEIDSFANPNNEFRAISNEEARSKSLLLKIHNMAMFICPP (2)
IAKLMNRLGFESAILTALRDMMKRTIEFRESNNVVRKDLLQLLIRLRNTGRIGEDDDEVWDMETVQEEL
KAMSIEKIAAQAFLFYVAGSESTAAAAAFTLYELAMYPELLKEARDELDTVLQRHNLEGT
GKLTYEAVHDLKFLDLCLK (1)
ETLRKYPGLPFLNRECTEDYLVPGTRHTITKGTPILISLFG
IHRDPVYFPNPEGYDPHRFDADKMNYDQAAYMPFGEGPRHCI (1)
ALRMGEVNTKVAVAKILANFDLVQAPHKEVGSASMLLPSWCPKRV

>6d4m AC017250 37993-39657 also AC008197 AC009846
MFSLILLAVTLLTLAWFYLKRHYEYWERRGFPFEKHSGIPFGCLDSVWRQEKSMGLAIYD
VYVKSKERVLGIYLLFRPAVLIRDADLARRVLAQDFASFHDRGVYVDEERDPLSANIFSL
RGQSWRSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELPEEGFKEVDIKKVMQNY
AIDIIASTIFGLDVNSFENPDNKFRKLVSLARANNRFNAMFGMMIFLVPS (2)
IAQFLFRIGFKNPVGLAMLQIVKETVEYREKHGIVRKDLLQLLIQLRNTGKIDENDEKSFSIQKTPD (1)
GHIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGKIT
YDSLNKMEFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHVIPKGTPVVISLYGIHHD
AEYFPDPETYDPERFSEESRNYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNV
EVMSRSEIEFENSGIALIPKHGVRVRLSKRVPKLS

>6d4ps ortholog found by Yi Jin
MFSLIVLAGTLLALGWFYLKHHYQYWERRGFPFDRQSTIPFGCLDSVWRREKGMGMAIYD
AYQKSKERFLGIYLLFRPAVLVRDAALARRVLAQDFASFHDRGVYVDEVNDPLSGSIFAL
RGQSWRSMRHKLSPCFTSGKLKGMFSTSEEIANNMVNHLQKTLPEQGSQEVDLKTVMQTY
AIDIIASTIFGLEMNSYLTPDNKFRNLVTIARRNTRFTTMFGMMIFLVPS (2)
VAKFLFSLGFKNQVALAMLEIVKETIEYREKHGIVRKDLLQLLMELRNTGAVDESDENIWKIQKSAT (1)
DQIKCISLESITAQAFIFYIAGQETTGSTAAFVLFELAQYPELLERLQTEVDETLAKNDGHIT
YDALQKMEFLDLCVQESLRKYPGLPMLNRECTQDYTVPDTDHVIPKGTPVVISLYGIHHD
AEYFPEPETYDPDRYSEENRNFSPTAFMPFGEGPRICIAQRMGLLNAKLAIINVLKNFNV
EVMSKRQLEFENSGIALLPKNGVKVRLSKRLPK*

>6d5m AC018176 comp(132649-134791)
MIGIYLLIAAVTLLYVYLKWTFSYWDRKGFPSTGVSIPFGALESVTKGKRSFGMAIYDMY
KSTKEPVIGLYLTLRPALLVRDAQLAHDVLVKDFASFHDRGVYVDEKNDPMSASLFQMEG
ASWRALRNKLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKKLMAT (2)
YAIDIIATTIFGLDVDSFADPNNEFQIISKKVNRNNIEDIIRGTSSFLYPG (2) 
LEKFFVKIGWKQEATERMRELSNRTVDLREQNNIVRKDLLQLLLQLRNQGKINTDDNIWSAESTKNGVKSMS
KDLIAGQLFLFYVAGYETTASTTSFTLYELTQNPEVMEKAKEDVRSAIEKHGGKLTYDAISDMKYLEACIL (1)
ETARKYPALPLLNRICTKDYPVPDSKLVIQKGTPIIISLIGMHRDEEYF
PDPLAYKPERYLENGKDYTQAAYLPFGEGPRMCI (1)
GARMGKVNVKIAIAKVLSNFDLEIRKEKCEIEFGVYGIPLMPKSGVPVRLSLKK

>6D5ps ortholog Contig7891_Contig7492A.fa.196 75% to 6D5
MIGILLLVAAVSLLYVYLKWTFSYWDRQGFPSAGVTIPFGALDSVRRGKR
SFGMAIYDMYNATKEPVMGMYLTLRPALLVRDPQLAHDILVKDFASFHDR
GIYVDEKNDPMSATIFAMEGSNWRNLRAKLTPSFTSGKLKAMFSTSEAIG
DKMVAHLNGKLPKEGSQEIEMKELLLT (2)
YAVDIIASTIFGLDVDSFADPNN
EFLSITKTINQNTFTDILRGTTSFLFPG (2)
LEKIFVRLGWSQEGPERIRELS
NRTVDLREEKNIERRDLLQLLLQLRNTGKISNDDNMWSAQNDNKGLKSVS
KDLIAGQLFLFFVAGYETTASTAAYTIYELTQNPEVMARALEDVRSTLEK
HDGKLSYDAIQDMKYLEACVL (1)
ETARKYPALPLLNRVCTKEYQIPNSKLIV
KKGTPIIISLIGMHRDAENFPDPLAYKPERYLDENKNFNPTAYMPFGEGPHNCI (1)
GLRMGKVNVKIAVAKILSNFSLEMSKE
KREIEFSVHGIPLMPKGGVPVRISRKK

>6g1m AC015208 comp(21239-22935) also AC007440
MVLTEVLFVVVAALVALYTWFQRNHSYWQRKGIPYIPPTPIIGNTKVVFKMENSFGMHLS
EIYNDPRLKDEAVVGIYSMNKPGLIIRDIELIKSILIKDFNRFHNRYARCDPHGDPLGYN
NLFFVRDAHWKGIRTKLTPVFTSGKVKQMYTLMQE (0)
IGKDLELALQRRGEKNSGSFITEIK
EICAQFSTDSIATIAFGIRANSLENPNAEFRNYGRKMFTFTVARAKDFFVAFFLPKLVSL
MRIQFFTADFSHFMRSTIGHVMEERERSGLLRNDLIDVLVSLRKEAAAEPSKPHYAKNQD
FLVAQAGVFFTAGFETSSSTMSFALYEMAKHPEMQKRLRDEINEALVEGGGSLSYEKIQS
LEYLAMVVDEVLRMYPVLPFLDREYESVEGQPDLSLKPFYDYTLENGTPVFIPIYALHHDPK (0)
YWTNPSQFDPERFSPANRKNIVAMAYQPFGSGPHNCIGSRIGLLQSKLGLVSLLKNHS
VRNCEATMKDMKFDPKGFVLQADGGIHLEIVNDRLYDQSAPSLQ

>6G1ps ortholog Contig3295_Contig8282.292 80% to 6G1 
MALTEALFLIVGALSAVYIWFQRNHSYWQRKGIPYIPPTPIIGNTEPAFK
LKNSFGLHLSEIYSDPKMQDEAVVGVYALNKPCLIIRDPELIKSVMVKDF
NRFHNRYGRCDPHGDPLGSNNLFFVRDTHWKDIRTKLTPVFTSGKVKQMYTLMLE (0)
IAHDLEEHLKKHVQNNSNSGKYITEIKEVCAQFSTDSIATIAFGI
RANSLQNPNAEFRNHGRKLFSFTLSRAKDFFVAFFLPKLVSLLRIQFFTQ
EFAHFLRSTISHVMEERERTGFVRNDLIDVLVGLRKEAAEEPSKPHYARN
FDFLVAQAGVFFTAGFETSSSTMSFALYELAKNSHLQTRLRQEINEALVE
GGGNLSYEKIQSLEYLAMVVDEVLRMYPVLPFLDREYNSIKDQPDLSLKP
YYDFTFEHGTPVFIPIYGLQHDPK (0)
YWPKPEQFDPERFSPENRKSIEAMAYQPFGSGPHNCIGSRIGLLQTKLGL
VHILKNHSVKMCADTIKEMKFDPKGFVLQSLTGIYLEIVNDRLYEESAARVH*

>6g2m AC015208 19014-20624
MELVLLILVASLIGIAFLALQQHYSYWRRMGVREIRPKWIVGNLMGLLNMRMSPAEFISQ
LYNHPDAENEPFVGIHVFHKPALLLRDPEMVRNILVKDFAGFSNRYSSSDPKGDPLGSQN
IFFLKNPAWKEVRLKLSPFFTGNRLKQMFPLIEEVGASLDAHLRQQPLHNERMRCFDLEA
KELCALYTTDVIATVAYGVSANSFTDPKCEFRRHGRSVFEFNLLRAAEFTLVFFLPHLVP
FVRFKVVPAEATRFLRKTINYVMSEREKSGQKRNDLIDILIEFRRSTQLAKASGIKDQFV
FEGDILVAQAVLFFTAGFESSSSTMAFAMYELAKDTDVQQRLREEIKDALVESGGQVTLK
MIESLEFMQMILLEVLRMYPPLPFLDRECTSGRDYSLAPFHKKFVVPKGMPVYIPCYALH
MDPQ (0)
YFPQPRKFLPERFSPENRKLHTPYTYMPFGLGPHGCIGERFGYLQAKVGLVNLLRN
HMITTSERTPHRMQLDPKAIITQAKGGIHLRLVRDALGV

>6g2ps Drosophila pseudoobscura sequence P. Khandelwal
MVLGLFLLVVIFLATICFLLQQHYAYWRRRGVRELRPHWILGNLAGLLSMRDSPADFMGQ
LYNHPDALNQPFVGIHVFHRPALLLRDPDLIKRILIKDFGKFSNRYSNSDYKGDPLGSQN
IFFLKNPAWKEVRFKLSPFFTSNKLKSMFPLIVEVGSNLDAYLREQPLHNERTRCFDLEA
KELCALFTTDVIASVAYGVQANSFTQPNGEFRRHGRAVFEFSLKRAAEFTLVFFLPHLVP
LFGFKVVPSEATRFLRNTINYVMAERERSQQTRNDLIDILIEFRRSTQQARAAGDHGQFV
FEGDILVAQAVLFFTAGFESSSSTMAFAMYELAKDADIQLRVRHEIKEALIASGGQVTLQ
LIDSLEYMQMVLLEVLRMYPPLPFLDRECTAEDEDYSLTPYHGFRVPKGMPIYIPCYALHMDPQ (0)
YFPQPRKFQPERFSPTNRKLQTPYTYMPFGLGPHGCIGERFGLLQAKVGLVNLMRN
HQVTTSERTPRRMKLDPKAIILQAQGGIHLRLVRDPLGI*

>6t1m AC012831 comp(42975-44564) no introns
MIAVFSLIAAALAVGSLVLLPVVLRGGCLLVVTIVWLWQILHFWHWRRLGVPFVPAAPFV
GNVWNLLRGACCFGDQFRELYESKEAAGRAFVGIDVLHNHALLLRDPALIKRIMVEDFAQ
FSSRFETTDPTCDTMGSQNLFFSKYETWRETHKIFAPFFAAGKVRNMYGLLENIGQKLEE
HMEQKLSGRDSMELEVKQLCALFTTDIIASLAFGIEAHSLQNPEAEFRRMCIEVNDPRPK
RLLHLFTMFFFPRLSHRVGTHLYSEEYERFMRKSMDYVLSQRAESGENRHDLIDIFLQLK
RTEPAESIIHRPDFFAAQAAFLLLAGFDTSSSTITFALYELAKNTTIQDRLRTELRAALQ
SSQDRQLSCDTVTGLVYLRQVVDEVLRLYPPTAFLDRCCNSRTGYDLSPWNGGSPFKLRA
GTPVYISVLGIHRDAQYWPNPEVFDPERFSAEQRQQHHPMTYLPFGAGPRGCIGTLLGQL
EIKVGLLHILNHFRVEVCERTLPEMRFDPKAFVLTAHNGTYLRFVKNSL

>6t1ps D. pseudoobscura ortholog 77%  1 intron, found by SunHong Kim
MILVIGVLFIAATVAAIGLLFFVVFPLVCAAGLIIFGIIWLWQRHHFCHWLRLGVPYIRA
TPFVGNVWKLLRGSCCFGDQFRQLYESKEAAGHAYVGIHVLHNHALLLRDPALIKRILVE
DFSQFSSRFETTDPIGDTMGAQNLFFSKHETWRETHKIFAPFFAVSKVRQMYGLLEHIGQ
QLEEHMEDQLNGKSEIELEVKQLCALFTTDIIASLAFGLEAHSLQKPDAEFRRMCVEVND
PRPKRLLHLFTMFFFPRLSRMVRTHLYSDEYERFMRQSMDFVLAQREKSGEKRHDLIDIF
LQLKRTEPPTSIIHRPDFFVAQASFLLLAGFDTSSSTITFALYELAKAPAIQKRLRDELS
DALRTNRHQPLNFDSVNGLSYLRQVVDEVLRLYPPTAFLDRCCNDENGYDLSAWNCGRAL
KLPAGAPVYISVLGLHRDPV (0)
HWPNPNQFDPEHFSPEQREQHHPMTYLPFGAGPRGCIGTLLGQLEIKVGLLHILKNFRVE
LCERTLPEMVFDPKAFVLTAKGGTYLRFVKDTL*

>6t2pm AC014742 1042-2504 64% to 6t1
MVIAFFIFL*CAALAVGSVVLLPLIALLAVWLWQRRHFRIWRRLGVPYLPAAPVLGNVLNVE 
CCFGDQFRELYERKEAAGRAIVGINVLHSHALLLRDPALIRRILVEDFPEFSSSF
KSTDAIRDTMGSGNLLFTKYKTWWETHKIFA 
LYGLLERI*QNLEAHMKKK 
KLNGAESVELEVKQLCALFTTDI 
LQSLQNPEAEFRPMCIEVNDPKPKRLSHHLFT 
RVRTHLYSEEYERFMRKSMNYVLAQRAEN*EKRYDLIDMFLQMHRTETAEGIIHRPDFYVAQAAF 
LLLAGFDTSSSFALYELAKNPTIEHRLQAELRVDLQSSHNHQLSYDTL
TGLVYLRQVLED 
LPFGAGPRGCIGTLLGQLGIKVGLLHTLKHFRVELCERTLPEMRFDP*
ASVLTAHNGTFLRFVRNSL*

>6t3m AC015208 comp(17123-18689)
MLLIWLLLLTIVTLNFWLRHKYDYFRSRGIPHLPPSSWSPMGNLGQLLFLRISFGDLFRQ
LYADPRNGQAKIVGFFIFQTPALMVRDPELIRQVLIKNFNNFLNRFESADAGDPMGALTL
PLAKYHHWKESRQCMSQLFTSGRMRDVMYSQMLDVASDLEQYLNRKLGDRLERVLPLGRM
CQLYTTDVTGNLFYSLNVGGLRRGRSELITKTKELFNTNPRKVLDFMSVFFLPKWTGVLK
PKVFTEDYARYMRHLVDDHHEPTKGDLINQLQHFQLSRSSNHYSQHPDFVASQAGIILLA
GFETSSALMGFTLYELAKAPDIQERLRSELREAFISTATLSYDTLMTLPYLKMVCLEALR
LYPAAAFVNRECTSSASEGFSLQPHVDFIVPPGMPAYISILGLHRDER (0)
FWPEPCVFDPERFGPERSRHIHPMTYIPFGAGPHGCIGSRLGVLQLKLGIVHILKQYWVET
CERTVSEIRFNPKSFMLESENEIYLRFCRSSL

>6t3ps D.Pseudoobscura 6t3 found by A. N. West
MVSLWLLMLGILSIYLWLRQRYSYFERHNIVHLPVSAWTPLGHLRKLLLLRISFGDLFHN
IYADPRGGQAKVVGFFLFQTPALMVRDPELIRLVLIKHFNSFLNRYEAADAAGDPMGSLT
LPLAKYHNWRESRQSMAQLFTSGRMRESMYPLMMGVVIDLEQYLQRKLGDRSERMLPLSK
MCQLYTTDVTGNLFYSMDVGGLRRGKSQLLKKTKELFDPDPRKVLDFMSIFFLPQWTNLL
RAKVFSEEYAQFMRGLVGHPRERSKGDLIDQLLHLQSSRPSSHYAQHPDFIASQASIILL
AGFETSSALLGFTLYELAKQPDLQKRLREELAEAFSLAPTLTYETLVTLPFLRKVCLEAL
RLYPAAAFINRECTSSDPNGFSLQPHVDFVVPNGMPAYISILGLHRDEK (0) 
YWPEPNRFDPERFDPDRSKDIIPMTYIPFGAGPHGCIGSRLGSLQLKLGLAHILRLCRVE
VCEQTVPQIRFNPKTFMLESKDEIYLRFYRDKL*

>6u1m AC017706 15959-17471 also AC008288
MHRTLLTALGALSVVYALVKFSLGYWKRRGILHEKPKFLWGNIKGVVSGKRHAQDALQDI
YTAYKGRAPFVGFYACLKPFILALDLKLVHQIIFTDAGHFTSRGLYSNPSGEPLSHNLLQ
LDGHKWRSLHAKSAEVFTPANMQKLLVRLSQISSRIQRDLGEKSLQTINISELVGAYNTD
VMASMAFGLVGQDNVEFAKWTRNYWADFRMWQAYLALEFPLIARLLQYKSYAEPATAYFQ
KVALSQLQLHRRRDRQPLQTFLQLYSNAEKPLTDIEIAGQAFGFVLAGLGPLNATLAFCL
YELARQPEVQDRTRLEINKALEEHGGQVTPECLRELRYTKQVLN (1)
ETLRLHTPHPFLLRRATKEFEVPGSVFVIAKGNNVLIPTAAIHMDPGIYENPQRFYPERF
EEQARRSRPAAAFLPFGDGLRGCIAARFAEQQLLVGLVALLRQHRYAPSAETSIPVEYDN
RRLLLMPKSDIKLSVERVDKL

>6u1ps D. pseudoobscura ortholog of 6u1 L. WEI
MDLLHRALLTAVGALSLFYALVKVSLGYWKRRGILHEKPKFFWGNIKGVVGGKRHLQDALQVI
YAKYKGRAPFVGFFACLKPFVLVLDLELVRHILVTHAGNFTTRGLYSNDGSEPLSGNLLQ
LDGHKWRALHAQSTGVFTPANINKLLPRIVLISRGVQRSLGKERLQTLNIN
ELVDSYNLDVVASMAFGLSADRTEFRRWTQSYWGKFSLWRAYLALEFPLLAQLLNHKSYA
VSAMTYFQKVVLGQLQEQRRRDRQPLQTFLQLYSNMDQPLDDVQIAAQAFGFVLAGLVPL
NATLSFCLYELARQPELQDRVRAEIRKTLEQHSGQLTTEGLKELLYTKQVLN (1)
ETLRLHTPYPFLLRRATKEFELPGSVFVIARGNNVLIPTAAIHRDPAIYEEPLRFDPDRF
ETEAKRTRPAMSFLPFGDGLRGCIAAQFVEQELLVGLVTLLQYHRYTPCSKTAIPLEYDN
GRLLLMPKTDIHLNVERVDN*

>6v1m AC011761 comp(54926-57766) also AC015002
MVYSTNILLAIVTILTGVFIWSRRTYVYWQRRRVKFVQPTHLLGNLSRVLRLEESFALQL
RRFYFDERFRNEPVVGIYLFHQPALLIRDLQLVRTVLVEDFVSFSNRFAKCDGRSDKMGA
LSLFLAKQPEWREIRTRLAPAFAGAKLKQMFSLMEE (0)
IGCDLEWYLKRLTRDLRRGDAERG
AIVSIKDVCDLYNTDMIASIAFGLRSYSLRNTQSEIGSHCQDLFRPNVRRIIDLFVIFYL
PKLVPLLRPKLFTEPHAEFLRRVIQLVIEERERGGDLRNDLIEMLLTLKKEADLQQDKSH
FTHHRDFLAAQAASFEVAGIETCSASMSFALYELAKQPLMQSRLRREIREAFASNPNGRL
TYEAVARMEFLDMVVEETLRKYPIVPLLERECTPINKKRFYSLRPHAECYTRRGMPVFISNLAIHHDPK (0)
YWPDPDRFDPERFSAANKALQAPMSYMPFGAGPRNCIGMQIGLLQIKLGLV
YFLHQHRVEICDRTVERIQFDAKFALLASEQRIYLKVDCL

>6v1ps ortholog FOUND BY I. Moisini
MVYSTNILLAIVTILTAVFVWSRRTYVYWQRRRVKFVQPAHLLGNLSKVLRLEESFALQL
RRFYFDERFRNEPIVGIYLFHQPALLIRDLSLVRTVLVEDFVSFSNRFAKCDLRHDKMGS
LNLFFAKQPEWREIRTRLSPVFTGAKIKQMFSLMEE(0)
IGCDLEYYLKRLTRDMRRSDASAR
GVIVSIKDVCDLYNTDMIASIAFGLRSYSLRSTQSEIGSHCQDIFRPNVRRIIDFFVIFY
LPKLVPLLRPRLFTEPHAEFLRRVIQLVIEERERGGDLRNDLIEMLLTLKKEADLQKDKS
HFTHHRDFLAAQAASFEVAGIETCSSSLSFALYELAKQPLMQARLRREIRETFEESPAGS
LSYELIGRMQYLEMIVEETHRKYPIVPLLERECTPINKKRFYSLRPHAECYARRGMPIYI
SNLAIHHDPK(0)
YWPDPERFDPERFSAENKSHQAPMSYLPFGAGPKHCIGMQIGQLQIKLGL
IYFLRRHRVELCEKTVERISFDAKFALLASEHRIYLKVADCL*

>6w1m AC014226 comp(15025-16689) also AC008257
MLLLLLLGSLTIVFYIWQRRTLSFWERHGVKYIRPFPVVGCTREFLTAKVPFFEQIQKFH
EAPGFENEPFVGVYMTHRPALVIRDLELIKTVMIKKFQYFNNRVLQTDPHNDALGYKNLF
FARSPGWRELRTKISPVFTSGKIKQMYPLMVK (0)
IGKNLQDSAERLGSGTEVQVKDLCSRFT
TDLIATIAFGVEANALQDAKSEFFYHNRAIFSLTLSRGIDFAIIFMIPALASLARVKLFS
RETTKFIRSSVNYVLKERERTGEKRNDLIDILLALKREAAANPGKMSKEVDLDYLVAQAA
VFQTAGFETSASTMTMTLYELAKNEALQDRLRQEIVDFFGDEDHISYERIQEMPYLSQVV
NETLRKYPIVGYIERECSQPAEGERFTLEPFHNMELPHGMSIYMSTVAVHRDPQYWPDPE
KYDPERFNSSNRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILRNHRFHTCDKTI
KKIEWAPTSPVMASKRDIILRVEKVSGKKDFGQK

>6w1ps D. pseudoobscura ortholog of 6w1 V. Lamba
MSTELLFLIATVAIVFYVWHKRRHSFWKRHGVKEIGPLPILGDTVGFLTGRLPFFDQIRK
FHEAPGLENEPIIGVYLAYRPALVIRDLDLVKTVMIKKFSYFTNRKLQTDPHDDALGYNN
LFFVRSPEWKELRNKISPVFTTGKIKQMYPLMVK (0)
IGKNLEANVGREPKDSIVTIKSLCAR
FTTDLIATIAFGLDANALQDPKSEFFRHNQAIFAPSVSRAIDFAIIFMLPALTTLAKVKV
FSKSTSQFIRSSINYVMAERERSGLRRNDLVDVLLALKREAAASPDKNNKAKNMDYLVAQ
AAVFQTAGYETSSSTMTLALYEVAKNEEIQNRLRQEIEEYFGDDDHISYERIQEMPYLSK
VVNETLRLYPIVGYAERECAQPSQGERFTLAPHHDMELPDGTPVYVSAVAIQRDPKHWPE
PEKFDPERFDASNRDKLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHLLRNHRVLWCDK
TVKTIEFAPFCGVLASKDEIYLRVERVSS*

>9b1m AC019916 10502-12238
MSFVEICLVLATIGLLLFKWSTGTFKAFEGRNLYFEKPYPFLGNMAASALQKASFQKQISEFYNRTRHH (2)
KLVGLFNLRTPMIQINDPQLIKKICVKDFDHFPNHQTLNIPNERLVNDMLN
VMRDQHWRNMRSVLTPVFTSAKMRNMFTLMNESFAQCLEHLKSSQPIAAGENAFELDMKV
LCNKLSNDVIATTAFGLKVNSFDDPENEFHTIGKTLAFSRGLPFLKFMMCLLAPKVFN (0)
FFKLTIFDSTNVEYFVRLVVDAMQYREKHNITRPDMIQLLMEAKKESKDNWTDDEIVAQCFI
FFFAAFENNSNLICTTAYELLRNLDIQERLYEEVKETQEALKGAPLTYDAAQEMTYMDMV
ISESLRKWTLSAAADRLCAKDYTLTDDEGTKLFEFKAGDNINIPICGLHWDERFFPQPQR
FDPERFSERRKKDLIPYTYLPFGVGPRSCI (1)
GNRYAVMQAKGMLYNLMLNYKIEASPRTTRDMWESARGFNIIPTTGFWMQLVSRK

>9b2m AC019916 8190-9903
MALIEICLALVVIGYLIYKWSTATFKTFEERKLYFEKPYPFVGNMAAAALQKSSFQRQLTEFYERTRQH (2)
KLVGFFNMRTPMITLNDPELIKKVCVKDFDHFPNHQPFITSNDRLFNDMLS
VMRDQRWKHMRNTLTPVFTAAKMRNMFTLMNESFAECLQHLDSSSKTLPGRKGFEVDMKV
MCNKLSNDIIATTAFGLKVNSYDNPKNEFYEIGQSLVFSRGLQFFKFMLSTLVPKLFS (0)
LLKLTIFDSAKVDYFARLVVEAMQYREKHNITRPDMIQLLMEAKNESEDKWTDDEIVAQCFI
FFFAAFENNSNLICTTTYELLYNPDVQERLYEEIVETKKALNGAPLTYDAVQKMTYMDMV
ISESLRKWTLAAATDRLCSKDYTLTDDDGTKLFDFKVGDRINIPISGLHLDDRYFPEPRK
FDPDRFSEERKGDMVPYTYLPFGVGPRNCI (1)
GNRYALMQVKGMLFNLLLHYKIEASPRTIKDLWGSASGFNFTPRSGFWMHLVPRK

>9B2ps ortholog found by C. Lancaster 73% to 9b2 68% to 9b1 
MVCLEICLAILVLGFMIYKWSTATHRAFDERGVYFEEPKPFFGNIGTSMLGLTSFHKVLSAFYNRTRGH (2)
KVVGFFNLRTPMIQLNDPEIIKKICIKDFDHFPNHQLFLESNERLLNDMLS
VMRDQRWKHMRNTLTPVFTAAKMRSMFALMNDSFGECLEHLSRLSDGSKSGEGLEVDMKV
LCNKLSNDLIATTAFGLKVNSFESPDNEFYQIGQSLTFSRGSQLFKFLLATLIPKVFL (0)
FFNMKIFNGQKVEYFVRLVVDAMKYREEHNINRPDMIQLLMESKTESEDNWTDDEIVAQCFI
FFFAAFENNANLICTTSLELLENPDIQQRLYEEAKEVQESLKGSSLTYDAVQKMKYMDMV
ISESLRKWTLAPVTDRICSKDYTLTDDDGTKLFDFKVGDRVNIPIAGLHWDDKYFPEPQK
FDPERFSDERKNEIVPYTYLPFGVGPRNCI (1)
GNRYALMQVKGMLYNLLIRYKIERSPKTVKDLWEEARGFNLAPKAGYWMRLMPRK

>9c1m AC019937 comp(1757-3443)
MVFVELSIFVAFIGLLLYKWSVYTFGYFSKRGVAHEKPIPLLGNIPWSVLMGKESYIKHS (2)
IDLHLRLKQHKVYGVFNLRDPLYYLSDPELIRQVGIKNFDTFTNHRKGITEGFNDTSVIS
KSLLSLRDRRWKQMRSTLTPTFTSLKIRQMFELIHFCNVEAVDFVQRQLDAGTSELELKD
FFTRYTNDVIATAAFGIQVNSFKDPNNEFFSIGQRISEFTFWGGLKVMLYILMPKLMK (0)
ALRVPVMDMNNVDYFK KLVFGAMKYRKEQSIVRPDMIHLLMEAQRQFKAEQEGSAESAAQQD
KAEFNDDDLLAQCLLFFSAGFETVATCLSFTSYELMMNPEVQEKLLAEILAVKEQLGEKP
LDYDTLMGMKYLNCVVSESLRKWPPAFIVDRMCGSDFQLKDEEGEVVVNLREDDLVHINV
GALHHDPDNFPEPEQFRPERFDEEHKHEIRQFTYLPFGVGQRSCIGNRLALMEVKSLIFQ
LVLRYHLKPTDRTPADMMSSISGFRLLPRELFWCKLESRGPA

>9c1ps D. Pseudoobscura K. Earhart and T. Liu
MAFEVLLALGALIGFLLYKWAEPPVRFFLKRGVVHEAPVPLLGNIPLAVLMGKASYLKHS (2)
IAVHMRLKQHKVYGVFNLRDPLFFLSDPELIRQVGIKSFDNFANHRKGLGDAGGGANDSV
LSKSLLSLRDRRWKQMRSTLTPTFTSLKIRLMFELIQVCNVEAVAYIERKLAEDGATELE
LKDFFTRYTNDVIATAAFGIQVNSFKDPNNEFFSIGQRISDFSLWAVLKVMLFILLPKLMK (0)
ALRVSVMDMNNVDYFKKLVFGAIQHRKEHNIIRPDMIQQLMEAQRLFRAEQEASQETTT
QEDRAEFNDEDLLAQCLLFFSAGFDTVATCLSFTSHELLMNPEAQDKLYEEIMATEEQLG
GKPLDYDTLMGMKYMDCVVSESLRMWPPAFVLDRMCGSDFELRDEEGKVVLTLKKDELIN
IPVIALHHDPDNFPQPDEFRPERFDDDHKHEIKPFTYLPFGIGQRSCIGNRMALMEVKAL
LYGLVRRFRLEPAERTTTDMMGNIAGFRMMPRELFWCKFVARVDGEAKVQE* 

>9f2m AC017132 AC017240 AC009741 AC017170 AC007594 PLUS ESTs
MLWEFFALFAIAAALFYRWASANNDFFKDRGIAYEKPVLYFGNMAGMFLRKRAMFDIVCDLYTKGGSKK (2)
FFGIFEQRQPLLMVRDPDLIKQITIKDFDHFINHRNVFATSSDDDPHDMSN
LFGSSLFSMRDARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENEL
DMKDYCTRFTNDVIASTAFGLQVNSFKDRENTFYQMGKKLTTFTFLQSMKFMLFFALKGLNK (0)
ILKVELFDRKSTQYFVRLVLDAMKYRQEHNIVRPDMINMLMEARGIIQTEKTKASAVR
EWSDRDIVAQCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELT
YEAIMGMKYLDQVVNEVLRKWPAAIAVDRECNK 
DITFDVDGQKVEVKKGDVIWLPTCGFHRDPKYFENPMKFD
PERFSDENKESIQPFTYFPFGLGQRNCI (1)
GSRFALLEAKAVIYYLLKDYRFAPAKKSCIPLELITSGFQLSPKGGFWIKLVQRN

>9F2ps ortholog 83% FOUND BY W. JIANG
MLLEFVALLGIAFALFYRWATANNEFFKEKGIPFAKPKLYFGNMAQMFLRQKAMFDIVCDLYNKGGSNK (2)
VYGIFEQRQPLMMIRDPDLLRQITIKD
FDHFINHRNLFGTGTDDDPHDMSNLFGSSLFSMRDARWKDMRSTLSPAFTGLKMRQMFQL
MNQVAKEAVDCLKPDQQGSVQGTELDMKDYCTRFTNDVIASTAFGLQVNSFKERDNDFYS
MGKKLTTFGFLQNLKFMLFFTLKSLNK (0)
YIKVDLFDKKSTE
YFVRLVLDAMKYRQEHNIIRPDMINMLMEARGLFQTEKTKTTVIREWSDRDIVAQCFVFF
FAGFETSAVLMCFTAQELMENEDVQQKLYEEVQQVDIDLDGKELSYEAIMGMKYLDQVVS
EVLRKWPAAIAIDRECNKDITYELDGQTIEIKKGDYIWLPTCGFHRDPKYFENP
NKFDPERFSEENKANIQPFTYYPFGLGQRNCI (1)
GSRFALLEAKAVIYYLLKDYRFAPAKKSCIPMELASNGFQLT
PKSGFWVKFVPRN*

>9f3pm AC017132 AC017240 AC009741 AC017170 AC007594 PLUS ESTs
MLWEFLALFAIATALFYRWASANNDFFKDRGIAYEKPVLYLGNMAGMFLRKRAMLDIVCDLYTKGGSGK (2)
FFGIFAQRQPLLMVRDPDLIKQITIKDFDHFINHRNEFDTSSDDDPHDMSN
LFSSSLFSMRDARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENEL
DMKDYCTRFTNDVIASTAFGLQVNSFKDRENTFYQMGKKLTTFTFLQNMKFILLFALKSLNK (0)
ILKVEIFDRKSTQYFVRLVLDAMKYRQEHNIVRPDMINMLMEARGIIQTEKTKASAVR
EWSDRDIVAQCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELK
YLDQVVSEVLRKWPPAIAFDRECNK 
EAKAVIYYLLKDYRFAPAKKSCIPLELISSGFQLSPKGGFWIKLVQRN

>9h1m AC017648 8657-10342 also AC005450
MDQSMIALALFIILLVLLYKWSVAKYDVFSERGVSHEKPWPLIGNIPLKAMIGGMPVLKK
MIELHTKHTGSPVYGIYALRDAVFFVRDPELIKLIGIKEFDHFVNHNSMHNNIQESILSK
SLISLRDGRWKEMRNILTPAFTGSKMRIMYDLIQSCSEEGVIHIQEQLELSQDASIELEM
KDYFTRFANDVIATVAFGISINSFRRKDNEFFRIGQAMSRISAWSVVKAMLYALFPRLMK (0)
VLRIQVLDTKNIDYFSSLVTAAMRYRQEHKVVRPDMIHLLMEAKQQRLADLSDKSKDELY
YSEFTADDLLAQCLLFFFAGFEIISSSLCFLTHELCLNPTVQDRLYEEIISVHEELKGQP
LTYDKLTKMKYLDMVVLEALRKWPPSISTDRECRQDIDLFDENGQKLFSARKGDVLQIPI
FSLHHDPENFEDPEFFNPERFADGHALESRVYMPFGVGPRNCIGNRMALMELKSIVYQLL
LNFKLLPAKRTSRDLLNDIRGHGLKPKNGFWLKFEARQ

>9h1ps Ortholog OF D. pseudoobscura Jun SHEN
MEKWIVVLSLVAVLLVLLYKWSVAKYGILTERGVPHAQPKPLLGTIPIRGMFTGLPVLKY
MIEQHMQYQGSRVYGVYALRDPLIFLRDPDLIKLVGIKEFDHFVNHHSMHNNVQESILSK
SLISLKDARWREMRYILTPAFTGTKMRVMYQLIQSCSEEAVRHIGEQLAQSNTGAIELEM
KDYFTRFANDVIATVAFGLSVNSFRRKDNEFFRIGQALSKISVWSIVKAVLHALVPRLMK(0)
LLRIQVLDFEKIDYFTSLVKVAMRYRKEHNVLRPDMIHLLMEAKQLRHAELVNQSKDSSR
YADFTDEDLLAQCLLFFFAGFQIISSALCFLSYELCMNPEVQSELYSEILSVDRELDGKP
PTFDRLTRMKYLDMVVQEGLRKWPPSIATDRECNNDIDLCDESGEKLFSAKKGDVLQIPI
FPLHHDPENFAEPERFDPQRFSDERRDEIRPGTFLPFGLGPRNCIGSRLALMELKSIVYQ
LILGFRLVPAQKTSTNLLDNIMGHNLQPKDGFWLKFESRK*

>12a4m AC006091 85973-87865 also AC015190 AC008141 rev 9/11/2000
MLKVRSALSLIQSQKATLSLATQK (0)
RWQTNVATAEAREDSEWLQAKPFEQIPRLNMWALSMKMS MPGGKYKNMELMEMFEAMRQD
YGDIFFMPGIMGNPPFLSTHNPQDFEVVFRNEGVWPNRPGNYTLLYHREEYRKDFYQGV
MGVIPTQGKPWGDFRTVVNPVLMQPKNVRLYYKKMSQVNQEFVQR (2)
ILELRDPDTLEAPDDFIDTINRWTLESVSVVAL
DKQLGLLKNSNKESEALKLFHYLDEFFIVSIDLEMKPSPWRYIKTPKLKRLMRALDGIQE
VTLAYVDEAIERLDKEAKEGVVRPENEQSVLEKLLKVDRKVATVMAMDMLMAGVDT (0)
TSSTFTALLLCLAKNPEKQARLREEVMKVLPNKNSEFTEASMKNVPYLRACIKESQRLHPLIVG
NARVLARDAVLSGYRVPAGTYVNIVPLNALTRDEYFPQASEFLPERWLRSPKDSESKCPA
NELKSTNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNYPTENAFRSALIN
LPNIPLKFKFIDLPN

>12A4ps D. pseudoobscura ortholog 75% to 12A4 Marie van der Merwe
MLKVRTGLSIIQAQKAALSVSCPL (0)
RWQTTAAVAEPRNDEEWLQARPFKQIPSTTFLSTVRNF
MPGGKYRKLDIVELFQALQDDY
GDIFYLPGIMGGPSFLTTHNPKDFEVVFRNEGVWPNRPGSDTLRYHRQTHRKDFFQGVEG
VIPTQGKTWSDFRSTVNPVLMQPKNVRLYYKKMSQVNQEFVQR (2)
IKTLRDVDTQEVPDDFISIINRWTLESVSVVALDKQLGLLKESGDNDLAVLLFKHLD
DFFELSADLEIKPSIWRYVKTPKLMKLMKALDGVQEVTLAYVDEAIERLEKEAKEGVVRP
ESEQSVLEKLLKVDKKVATVMAMDMLMAGVDT (0)
TSSTFTAALLCLAKNPEKQAILREEVMK
VLPEKDSEFTEASMKNVPYLRACIKESQRLYPLVIGNIRVLNRDSVLSGYQVPAGTFISM
VPTSLLSSEEHFLKANEFLPERWMRSATDSTGECPANDLKLKNPFVFLPFGFGPRMCVGK
RIVDMELELGIARLIRNFSIEFNHPTEKAFRSSLISLPNIPLKFKFTDLPN

>12a5m AC006091 8344985296 also AC015190 AC008141
MLKGRIALNILQSQKPIVFSASQQ (0)
RWQTNVPTAEIRNDPEWLQAKPFEEIPKANILSLFA
KSALPGGKYKNLEMMEMIDALRQDYGNIIFLPGMMGRDGLVMTHNPKDFEVVFRNEGVWP
FRPGSDILRYHRTVYRKDFFDGVQGIIPSQGKSWGDFRSIVNPVLMQPKNVRLYFKKMSQ
VNQEFVEL (2)
IKEIRDASTQEVPGNFLETINRWTLESVSVVALDKQLGLLRESGKNSEATKL
FKYLDEFFLHSADLEMKPSLWRYFKTPLLKKMLRTMDSVQEVTLKYVDEAIERLEKEAKE
GVVRPEHEQSVLEKLLKVDKKVATVMAMDMLMAGVDT (0)
TSSTFTALLLCLAKNPEKQARLR
EEVMKVLPNKDSEFTEASMKNVPYLRACIKESQRVYPLVIGNARGLTRDSVISGYRVPAG
TIVSMIPINSLYSEEYFPKPTEFLPERWLRNASDSAGKCPANDLKTKNPFVFLPFGFGPR
MCVGKRIVEMELELGTARLIRNFNVEFNHSTKNAFRSALINLPNIPLKFKFTDVPN

>12A5ps ortholog Contig8255_Contig717.47 76% to 12A5
MLKVRSGLSIIQAQKAALSVSSPL (0)
RWQTTAAVAEPRNDEEWLQARPFEQI
PSTTFLSTVRNF MPGGKYSKLDIVNLFKALQDDYGNILYLPGMMGGTSYL
MTHNPKDFEVVFRNEGVWPHRPGSDTLRYHRKTHRKDFFQGVEGAIPTQG
KTWSDFRSAVNPVLMQPKNVRLYYKKMSQVNQEFVQR (2)
IKALRDIDTQEAP
DDFLTVINRWTLESVSVVALDKQLGLLKESDDNDQAVLLFKYLDDFFELT
ADLEMKPSIWRYFKTPKLMKLMKALDGVQEVTLAYVDEAIERLEKEAKEG
VVRPENEQSVLEKLLKIDKKVATVMAMDMLMAGVDT (0)
TSSTFTAALLCLAK
NPEKQAILREEVMKVLPEKDSEFTEASMKNVPYLRACIKESQRIYPLVIG
NGRVLNRDSVLSGYQVPAGTCVSMIPLRLLSSEEHFPKAAEFLPERWIRN
ATDSSGVCPANDLKLKNPFVFLPFGFGPRMCVGKRIVDMELELGIARLIR
NFNIEFNHPTENAFRSAMISLPNIPLKFKFTDLPN*

>12b2m AC018326 72279141 also AC004345 AC004657
MWKYSNKIIYRNVSGNQLWFNRNSSVGGTLSQQ (0)
TQLELADSRIDEKWQQARSFGEIPGPSLLRMLSFFMPG (1)
GALRNTNLIQMNRLMREMYGDIY
CIPGMMGKPNAVFTYNPDDFEMTYRNEGVWPIRIGLESLNYYRKIHRPDVFKGVGGLASD (2)
QGQEWADIRNKVNPVLMKVQNVRQNLPQLDQISKEFIDK (2)
LETQRNPETHTLTTDFHNQLK
MWAFESISFVALNTRMGLLSDNPDPNADRLAKHMRDFFNYSFQFDVQPSIWTFYKTAGFK
KFLKTYDNITDITSNYIETAMRGFGKNDDGKTKCVLEQLLEHNKKVAVTMVMDMLMAGIDT (0) 
TSSACLTILYHLARNPSKQEKLRRELLRILPTTKDSLTDQNTKNMPYLRACIKEGLRIT
SITPGNFRITPKDLVLSGYQVPRGTGVLMGVLELSNDDKYFAQSSEFIPERWLKSDLAPD
IQACPAARTRNPFVYLPFGFGPRTCIGKRIAELEIETLLVRLLRSYKVSWLPETPIEYES
TIILSPCGDIRFKLEPVGDLM

>12B2ps ortholog Contig3295_Contig8282.217 76% to D. melanogaster 12B2
MWKNTMKTVRRQSAAHQLFNARDLSLNRTLGQQ (0)
THLELLDKSPPRTDERWQQAKSYGELPGPNGWRMISYFLPG (1)
GKLHNTNLIQMNRRLRVMYGDIYRLPGLMGKPDIVFT
YNPEDFELTYRNEGVWPIRIGLESFSYYRKVKRPDVFGGIGGLVSE (2)
QGKDWADIRNKVNPVLMKVQNVRQNLPQLDQIAKEFIDK (2)
LESQRDPETHLLQDDFHDQLKNWAFESISFVALNTRMGLLSDQPDPNAARLAKHMSDFVN
YSFQYDVLPSIWPYYKTRGFNRFLKTYDDITEITTNYIEEAIQRFKIDDGRKNKCVLEQL
LGLNKQVAVVMAMDMLMAGIDT (0)
TSSAFVTILYHLACNPSKQSQLRRELL
HILPDSKGSLTDESTKNMPYLRACIKEGLRITSITPGNFRITTKDLVLSG
YQVPRGTGVLMGVMELSNSDEYFAQSADFIPERWLKADLAGDVLACPEAR
TRNPFVYLPFGFGPRTCIGKRIAELEIETLLVRLLRRYHVNWLPNAPLQY
KSTIILSPCGDIRFKFLPVEGVRESL*

>12c1m AC009385 comp(57935-59646) also AC012807
MLRLTVKHGLRANSQLAATRNPDASSYVQQLESEWEGAKPFTELPGPTRWQLFRGFQKGG
EYHQLGMDDVMRLYKKQFGDICLIPGLFGMPSTVFTFNVETFEKVYRTEGQWPVRGGAEP
VIHYRNKRKDEFFKNCMGLFGN (2)
GAEWGKNRSAVNPVLMQHRNVAIYLKPMQRVNRQFVNR
IREIRDKESQEVPGDFMNTINHLTFESVATVALDRELGLLREANPPPEASKLFKNIEVLM
DSFFDLGVRPSLYRYIPTPTYKKFSRAMDEIFDTCSMYVNQAIERIDRKSSQGDSNDHKS
VLEQLLQIDRKLAVVMAMDMLMGGVDTTSTAISGILLNLAKNPEKQQRLREEVLSKLTSL
HSEFTVEDMKSLPYLRAVIKESLRLYPVTFGNARSAGADVVLDGYRIPKGTKLLMTNSFL
LKDDRLYPRAKEFIPERWLRRKDDDKSDVLMNKDLNAFIYLPFGFGPRMCVGKRIVDLEM
ELTVANLVRNFHIEYNYSTEKPYKCRFLYKPNIPLKFKFTDLKY

>12c1ps D. pseudoobscura ortholog of Cyp12c1 Y. Zong 65% 
MIRRAVVQQGIRARSSLAEVQVISKKNLDPAAASSSYMEQLEGEWSTAKPFEEIPGPTRWQLWRGFQKGG
EFHHLDMAELMDLYRSRFGDMVRVPGLFGMPTTVFTFKVENFERIYRAEGQWPVRGGADP
VLHYRANRKDGFFKDCVGLFSN (2)
GPEWGRLRSAANPVLMQHRNANLYLEPMQRVNNQFIDRIRATRDKESLEMPGDFLDTINTL
TFESVAVVALDRELGLLRDSDQKPEAKELFRNIKIFLQSFFDLGIKPSVYKYISTPTYRKF
SQASDAIFDTCSMYVNEAVARIDGQSAAEREGRRSILEQLLQINRKFAVVMAMDLLFGAVD
TTTSALAGVLLSLAKNPKQQQMLREEIVSMLPHPDRQFTLAEMKSLPYLRACIKESMRMFP
VTFGNIRSAGTDVVLDGYRIPQGTNLLMLSSNMLRDERFYPRPNEFLPERWARPQDDNSAE
SPLRNNLNPFVYLPFGFGPRMCVGKRIVDLEMELTVANLVRNF
HIEFNYPIENAFKRSFLNMPNIPLRFKFTDVNYS*

>12d1m AC008187 comp(84371-86114)
MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSS (0)
ITEEHKTYDEIPRPNKFKFMRAFMPG
GEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLD
SIVYFREHVRPDVYGEVQGLVAS (2)
QNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIER (2)
IKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRD
IFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVAQKMLKENQDALEKRRQAGEKINS
NSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMP
TKDSLLNEENMKDMPYLRAVIKETLRYYPNGLGTMRTCQNDVILSGYRVPKGTTVLLGSN
VLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETT
VAKLIRNFHVEFNRDASRPFKTMFVMEPAITFPFKFTDIEQ

>12d1ps D. pseudoobscura ortholog of Cyp12d1 Y. Zong 
MNAWQSLTRRLAVATGPIRSLRGSSAQAQAQRSVEDVEARPFSEVPRPGR
LQFMRSFMPGGEFSDASIVEFSMGMRRRYGDIFILPGMFGRKDWVVTFNT
GDIATVFRNEGAWPHREAFDSIVHFRQHIRPDVYGRTLGLTVG (2) 
QGEDWGKMRSAVNPIFMQPRGLRMYFEPLSNINNEFIER (2)
IKEIRDPSTLEVPSNFND
EMQRLIFESLALVSFDRQMGIIRKHRDNPDALALFRTSRDIFRYTFQLDV
QPSAWKIVSTPTYRKMMRTLNESLDVAQRVLAESQQLLEHRRRAGEQVNS
HSMLQRLMDIDPKLALIMGLEILFAGVDATATLLSAVLLTLAKHPEKQHK
LRAEVRQVMPSKESLLNEDTMRDMPYLRAVIKETLRFYPNGLGTLRSCPT
GVTLSGYAVPPGTTVLLAANALMKDPAHYPRPDEFLPERWLRDPQSGQKM
QVSPFTFLPFGFGPRMCLGKRVVDLEVETSVAKLIRNFHVEFLHDASRPY
KTLFVMEPAIDFRFRFTDIQE*

>12e1m AC018294 2070-3932 N-term revised
MLSTQWNANKQISRQIYQLCR (1)
VLNLEEAKPYADIPGPSKLQLIRAFLPG (1)
GLYKNLPVHEMFLDMNRQYGSIFRMPSVAGTDLVLTMNPQDYEVIFRNEGQYPYRR
SFEVMDYFKRVHRREVFDGYDGLTSG (2)
NGPAWGKMRTAVNPILLQPRNAKLYMTNLVQVSDEFLER (2)
IRIIRDPVTQEMPDDFAVDIRHLVIESICSVALNTHLGLLGEQRNNKDIQKLVLA
LQDVVELGFQLDIMPAFWKYLPMPNFKKLMRSLDTITDFCYFHIGNALKRIEEDAKAGTL
NEIGLETSLLEKLARFDRQTAVIIAMDLLFAGADP (0)
TLVTLGGILFSLSKSPDKQARLLEE
IRGILPNKDSSLTIENMRNLPYLRACIKEGIRMYPIGPGTLRRMPHDVVLSGYRVVAGTD
VGIAANYQMANMEQFVPKVREFIPERWLRDESNSHLVGETATPFMYLPFGFGPRSCAGKR
IVDMMLEIAISRLVRNFKIGFDYPIENAFKAQFFVQPNIPFKFKFIERNE

>12e1ps D. pseudoobscura 12e1 ortholog 77% Van Alstine
MLSQQLNAKRQASCQIYQIYRN (0)
ETISLEQAKPYAEVPGPSKFQMIRAFMPG (1)
GRYKNAPAHEMFLDLSRQFGGLFRMPSIAGTDMVLTMNPQDYATVFRN
EGQWPHRRSFTTVEYFRKVRRPEVFGEYDGLLSG (2)
NGAAWGKMRTAVNPILLQPRNAKLYLKNLVQVSDEFLER (2)
IRLIRDPVSQEMPDDFTEDIRNLVIESIGSVALNTHLGLLGENRYSDEANQ
LKAAMRDFVELGFQLDMMPAIWKYLPVPKFNQLMRSLDTMTDFCVTHIEQALQR
IEEDVKAGKMSPEMGMEASLLEKLARFDRKTAVIIAMDFLFAGTDP (0)
TLVSLVGILLSLAKNPDKQARLLEEINQILPAKDSPLTIENMSNLPYLRACIKEGIRLYPIGPGTV RRMPHDVVLSGYRIVAGTDVAIAANYQMANMEEYVPRVREFLPERWLRDESNSKLVGDTATPFMYLPFGF
GPRACAGKRIVDMMLEIGVARLVRNFEIGFDYPIENAFKTQFFVQPNIPFKFKFVERTA*

>18a1m AC012164 114600-117669 also AC015216
MLADSYLIKFVLRQLQVQQDGDAQHLLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGL
PVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRREEFTGRPDTPFMQTLNGY (1)
GIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIM (0)
TEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVD
YIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAK
AEGTDAELFDGKNH (1)
EEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQ
VVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTR (2)
DVELNGYTIPAGSHVIP
LINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFF
ASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRRPLGPTAADPHHMRNVGAN

>18a1ps D. pseudoobscura ortholog of Cyp18a1 96% FOUND BY W. JIANG
MLADSYLIKFLLRQLQVQQQDAGAQHLLMVFLGFLALVSLLQWMLRHYRELRKLPPGPWG
LPVIGYLLFMGNEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRREEFTGRP
DTPFMQTLNGY (1)
GIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIM (0)
TEVHEFIGHLHASDGQPIDLSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMR
LFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPHNVRDLVDY
YLCEIEKAKAEGTDAELFDGKNH (1)
EEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQY
LPVTESTILESMRRSSIVPLATTHSPTR (2)
DVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGR
RMCLGDVLAKMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPEAFKVCLKRRPLA
PTATDPHHMRNVGSN*

>28a5m AC018242 6065-8082 also AC001660
MVLITLTLVSLVVGLLYAVLVWNYDYWRKRGVPGPKPKLLCGNYPNMFTMKRHAIYDLDDIYR (2)
QYKNKYDAVGIFGSRSPQLLVINPALARRVFVSNFKNFHDNEIAKNIDEKTDFIFAN
NPFSLTGEKWKTRRADVTPGLTMGR (0)
IKTVYPVTNKVCQKLTEWVEKQLRLGSKDGIDAKH (0)
MSLCFTTEMVTDCVLGLGAESFSDKPTPIMSKINDLFNQPWTFVLFFILTSSFPSLSHLI
KLRFVPVDVERFFVDLMGSAVETRRAQLAAGKQFERSDFLDYILQLGEKRNLDNRQLLAY
SMTFLLDGFETTATVLAHILLNLGRNKEAQNLLREEIRSHLQDGTIAFEKLSDLPYLDACVQ (1)
ETIRLFPPGFMSNKLCTESIEIPNKEGPNFVVEKGTTVVVPHYCFMLDEEFFPNPQSF
QPERFLEPDAAKTFRERGVFMGFGDGPRVCI (1)
GMRFATVQIKAAIVELISKFNVKINDKTRKDNDYEPGQIITGLRGGIWLDLEKL*

>28A5ps L. Hunt
MILITLALGLATVGLLYLLMTWNFDHWRKRRVPGPKPKIPTGNYPHMYTMKRHAIYDLNDIYV (2)
KYKNKYDAVGIFGGRVPQLLVISPELARRVFVSDFKHFHDNEVSNLIDEKSDFIFAN
NPFSLTGDKWKQRRADVTPGLTMGR (0)
IKTVYPVTNKVCQKLSEWVDKQIRLGAPEGINAKD (0)
MSLCFTSEMVTDCVLGLSAESFSDNPTPIMGHIKDLFSQSWSFLIYFVIISTFPSLSHLI
KLRFVPPKVERFFIELMENAVKARRAQLVAGKQFERTDFLDYILQMAEKRSLDTRQLLAH
TMTFLLDGFETTATVLAHMLLLLGREPEAQKRLREEILAHVKDGIVSFEKLNELPFLDACVQ (1)
ETIRIFPPAFMSNKLCTEAIELPNKDGPNFTVEVGTTIVIPHYCFMLDEDYFPDSQSF
QPDRFMEPDAAKKFRERGTFMGFGDGPRVCI (1)
GMRFALAQIKAAAVELITKYNVKVNPKTRKDNLYDPMSFITSLQGGIWLDLEAL*

>28c1m AC014191 comp(8254-10002) also AL133495
MFGSLLLGIATLLGAIYAFLVSNFGHWRRRGVTEPRALPLFGSFPNMIWPRQHFTMDMRDIYM (2)
HYRNTHSYVGCYLLRAPKLLVLEPRLVYEIYVSAFSHFENNDASKMVDIAKDRLVAL
NPFVLEGEEWRHQRAVFSTLLTNGRIRTTHAIMQRVCLDLCQFIAIKSAGGKDLDCID (0)
LGLRFTGESLFDCVLGIQARTFTDNPLPVVRQNHEMSAENRGLAIAGAVHGLFPNLPRWLRP
KVFPRSHDRFYGQMISEALRLRRSKHQERNDFINHLLEMQRELDLSEEDMASHAMTFMFD
GLDTTSNSIAHCLLL (0)
LGRNPDCQRRLYEELQLVNPGGYLPDLDALIDLPYLSACFN (1) 
ESLRIYPAGGWASKTCTKEYELRGSHHSEPLKLRPGDHVMVPIYALHNDPDLYPEPDVFRPERF
LDGGLKNCKQQGIFLGFGNGPRQCVGMRLGLAMAKAALAAIVQRFEVVVSPRTLNGTELD
PLIFVGVHKGGIWLQFVPRKNVTTK

>28c1ps ortholog Y. Abdelrahman
MIGSLLLAVGALATLVYGFLVWNFGHWRARGIKEPRALPLLGSFPNMVWPRQHFTMDMRDLYM (2)
KYRETDSYVGTFLLRSPKLLLLEPRLVYEVFVSAFRHFEDNDAARMVDTGKDVLVCCNPFVLEGNEWRQQRGIFSSLLTNGRIRTTHTIMQRVCRDLCDFIAKESLKGEPQDGMD (0)
LGLRFTGDSLFDCVLGIQARCFSDSPLPVIRHNREMSNENPGLAIAGALNGLFPRLPRWLRP
KIFPRSYDRFFGDLIRQAFSLRRGQHQERNDFINHLLALKREHGLTEPQLTSHAMTFMFD
GLDTTSSTISHCLLL (0)
LGRYPECQQRLYEELDKASPSKELPDLDALNDLPYLSACFN (1)
ESLRIYPAGGWASKTCTEPYKLHGSHHSQPLQMLPGDNIMIPIYGLHHDPQFYPEPEEFRPERF
LDGGLKRFKQMGVFLGFGNGPRQCVGMRLGLAQAKAALAAIVQRFEVRVHPRTADGLELD
PYIFVGCHKGGIWLDFVSRPV*

>28d1m AC017780 comp(28385-30262) also AC009355 AC008324 AC008327
MCPISTALFVIAAILALIYVFLTWNFSYWKKRGIPTAKSWPFVGSFPSVFTQKRNVVYDIDEIYE (2)
QYKNTDSIVGVFQTRIPQLMVTTPEYAHKIYVSDFRSFHDNEMAKF (0)
TDSKTDPILANNPFVLTGEAWKERRAEVTPGLSANR (0)
VKAAYPVSLRVCKKFVEYIRRQSLMAPAQGLNA
KDLCLCYTTEVISDCVLGISAQSFTDNPTPMVGMTKRVFEQSFGFIFYTVVANLWPPITK
FYSVSLFAKDVAAFFYDLMQKCIQVRRESPAAQQRDDFLNYMLQLQEKKGLNAAELTSHT
MTFLTDGFETTAQVLTHTLLFLARNPKEQMKLREEIGTAELTFEQISELPFTEACIH (1)
ETLRIFSPVLAARKVVTEPCELTNKNGVSVKLRPGDVVIIPVNALHHDPQYYEEPQSFKPERF
LNINGGAKKYRDQGLFFGFGDGPRICP (1)
GMRFSLTQIKAALVEIVRNFDIKVNPKTRKDNEIDDTYFMPALKGGVWLDFVERN

>28d1ps D. pseudoobscura ortholog of 28d1 Wei Liu Contig3635_Contig7816.10
MCPICAVLLLLATLLTLIYIFLTWNFGYWKRRGIQTAKAWPLVGSFPSVFTQKRNMAYDIDEIYR (2)
QYKNTESVVGVFNTRIPQLMILCPEYAHKIFAGEFRSFHDNEIGKF (0)
TNKKVDKILANNPFILTGEDWKERRAEITPGLSANR (0)
VKAVYPVSQSVCKHFVEYIKRQQRMATSDGINAKDLCLCYTTEVVSDCVLGISAQSFTET
PTPLVGMIKRVFEQSFGFIFYTMAANLWPPIRKIYSVPLFAKEVEQFFFDIMEKCIILRR
ENPKQQREDFLNYMLQLQEKKGLDTTELTSHTMTFLTDGFETTALVLSHTLLLLGRNPAE
QRKVRDEIGKGDLTFEQLSELPYIDACIH (1)
ETLRLFAPLLSGRKLVTEAYDFVNKNGVTVRVHPGDVVIIPAHSMHHDPEYYEDPEVFKP
ERFLEINGGVRKYREAGVYYGFGDGPRVCP (1)
GMRFALTQVKAALVEIVQNFEIKVNPKTRSDNELDDTFFMATLKGGIWLDFEARK*

>28d2m AC017780 comp(31545-33456) AC008324 revised 9/11/2000
MCPVTTFLVLVLTLLVLVYVFLTWNFNYWRKRGIKTAPTWPFVGSFPSIFTRKRNIAYDIDDIYE (2)
KYKDTDNMVGVFTTRVPQLLVMCPEYIHKIYATDFRSFHNNEWRNF (0)
VNKKTDMILGNNPFVLTGDEWKERRSEIMPALSPNR (0)
VKAVYPVSQSVCKKFVEYIRRQQQMATSEGL
DAMDLSLCYTTEVVSDCGLGVSAQSFTDTPTPLLKMIKRVFNTSFEFIFYSVVTNLWQKV
RKFYSVPFFNKETEVFFLDIIRRCITLRLEKPEQQRDDFLNYMLQLQEKKGLHTDNILIN
TMTFILDGFETTALVLAHIMLMLGRNPEEQDKVRKEIGSADLTFDQMSELPHLDACIY (1)
ETLRLFSPQVAARKLVTEPFEFANKNGRTVHLKPGDVVTIPVKALHHDPQYYEDPLTFKPER
FLESNGGGMKSYRDRGVYLAFGDGPRHCP (1)
GMRFALTQLKAALVEILRNFEIKVNPKTRSDNQIDDTFFMATLKGGIYLDFKDL

>49A1m DROSOPHILA mel.SEQ (new N-term)
MSGLRKTSIALMRRSTSSTTILPHSGGVGGAVSPPSSGVGVATEIEKSIA
MQRLRTGESSNPKKLNVS (2) 
QQPVTSVATTRTTASSLPAETTSSPAAAVRPYSEVPGPYPLPLIGNSWRFAPLI (1) GTYKISDLDKVMNELHVNYGKMAKVGGLIGHPDLLFVFDGDEIRNIFKKEEAMPHR (2) 
PS MPSLRHYKGD LRRDFFGDVA GLIGV (2)
HGPKW EAFRQEVQHI LLQPQTAKKYIPPLNDIASE FMGR (2) 
IELMRD EKDELPANFL HELYKWALE (1)
SVGRVSLDTRLGCLSPEGSEEAQQIIEAINTFFWAVPELELRMPLWRIYPTKAYRSFVKALDQFTA (2)
ICMKN IGKTMDKADA  300
DEARGLSKSE ADISIVERIV RKTGNRKLAA ILALDLFLVG VDT (0) 
TSVAASS TIYQLAKNPD  360
KQKKLFDELQ KVFPHREADI NQNVLEQMPY LRACVKETLR (2)
MRPVVIANGRSLQSDAVINGYHVPKG (0) 
THVI FPHLVVSNDP AYFPEPKRFL PERWLKQSTD A (1) 
AGCPHANQK IHPFVSLPFG  480
FGRRMCVGRR FAEIELHTLL AK (0) 
IFRKYKVS YNSGEFVYRV NSTYIPQSPL NFKLTLRDE

>49A1ps ortholog 91% to CYP49A1 intron 8 missing possible extension to N-terminal
MSGLRKTSFALMRRSTYSGSATATMLPHAGPGPGTGVDGAAPPSGVGVATEIEKSIA
RQRLRQGQSETAKKLNVS (2) 
HLAATAVPATETATATATRTASPTAGVRPYSEVPGPYPLPLIGNSWRFAPLI (1)
GTYKISELDKVMNELHVNYGKMAKVGGLIGHPDLLFVFDGDEIRNIFKKEEAMPHR (2)
PSMPSLRHYKGDLRRDFFGDVAGLIGV (2)
HGPKWEAFRQEVQHILLQPQTAKKYIPPLNDIASEFMGR (2) 
IEAMRDEKDELPANFLHELYKWALE (1)
SVGRVSLDTRLGCLSPEGSEEAQQIIDAINTFFWAVPELELRMPLWRIYPTKAYRSFVRALDQFTA (2) 
ICMKNIGQTMDKAEADEARALPKSEADISIVERIVRKTGNRKLAAILALDLFLVGVDTTS
VAASSTIYQLAKNPDKQRRLFEELQRVFPHREAEINQNVLEQMPYLRACVKETLR (2) 
MRPVVIANGRSLQSDAVINGYHVPKG (0)
THVIFPHLVVSNDPAYFPEPKRFLPERWLKQTAAVA (1)
VGCPHASHKIHPFVSLPFGFGRRMCVGRRFAEIELHTLLAK (0)
IFRKYKVSYSSGEFVYRVNSTYIPQSPLNFKLTLRED

>301a1m AC017275 comp(35594-38192) also AC007356
MNNLSLKAWRSTVSCGPNLRQCVPRISGAGSRRAQCRESSTGVATCPHLADSEEASAPRI
HSTSEWQNALPYNQIPGPKPIPILGNTWR (2)
LMPIIGQYTISDVAKISSLLHDRYGRIVRFGGLIGRPDLLFIYDADEIEK (0) 
CYRSEGPTPFRPSMPSLVKYKSVVRKDFFGDLGGVVGV (2)
HGEPWREFRSRVQKPVLQLSTIRRYLQPLEVITEDFLVRCENLLDENQELPEDFDNEIHKWSLE (1)
CIGRVALDTRLGCLESNLKPDSEPQQIIDAAKYALRNVATLELKAPYWRYFPTPLWTRYVKNMNFFVG (2)
VCMKYIQSATERLKTQDPSLRAGEPSLVEKVILSQKDEKIATIMALDLILVGIDT (0)
ISMAVCSMLYQLATRPVDQQKVHEELKRLLPDPNTPLTIPLLDQMHHLKGFIKEVF
RMYSTVIGNGRTLMEDSVICGYQVPKGVQAVFPTIVTGNMEEYVTDAATFRPERWLKPQH
GGTPGKLHPFASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKLEYNHKPLDYAVTFMY
APDGPLRFKMTRV

>301A1ps ortholog D. pseudoobscura found by Michael Mohler
MNKLPVRACTASASSLRRTVSRISGSGLLPNEKQRLEIRDSSTGVAACPHLLEPEETAAP
TTPRIHSTPEWQNALPYNQIPGPKPLPILGNTWR (2)
LMPIIGQYTISDVANISSLLHDRYGRIVRFGGLIGRPDLLFIYDADEIEK (0)
CYRSEGPTPFRPSMPSLVKYKSVVRKDFFGELGGVVGV (2) 
HGEPWRQFRSRVQKPVLQLSTIRRYLQPLEAITDDFLVRCEHLLDGNQELPKDFDNEIHKWSLE (1)
CIGRVALDTRLGCLEANLSPDSEPQQIIDAAKYALRNVATLELKAPYWRYFPTPLWTQYVKNMNFFVG (2)
VCMKYIQSATERLKTQDPSQRAGEPSLVEKVIMSEKDEKIATIMALDLILVGIDT (0)
ISMAVCSMLYQLATRPEEQQKVHEELKRLLPDPNTPLTIQLLDQMHHLKAF
IKEVFRMYSTVIGNGRTLQEDSVICGYQVPKGVQAVFPTIVTGNMEEYVTDAATFRPERW
LKPQHGGVPGKLHPFASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKLEYNHKPLDYA
VTFMYAPDGPLRFKMTRI*

>302a1m AC015396 3195433705
MLTKLLKISCTSRQCTFAKPYQAIPGPRGPFGMGNLYNYLPGIGSYSWLRLHQAGQDKYE
KYGAIVRETIVPGQDIVWLYDPKDIALLLNERDCPQRRSHLALAQYRKSRPDVYKTTGLL
PTNGPEWWRIRAQVQKELSAPKSVRNFVRQVDGVTKEFIRFLQESRNGGAIDMLPKLTRLNLE (1)
LTCLLTFGARLQSFTAQEQDPRSRSTRLMDAAETTNSCILPTDQGLQLWRFLETPSF
RKLSQAQSYMESVALELVEENVRNGSVGSSLISAYVKNPELDRSDVVGTAADLLLAGIDT
TSYASAFLLYHIARNPEVQQKLHEEARRVLPSAKDELSMDALRTDITYTRAVLKESLRLN
PIAVGVGRILNQDAIFSGYFVPKG (0)
TTVVTQNMVACRLEQHFQDPLRFQPDRWLQHRSALN
PYLVLPFGHGMRACIARRLAEQNMHILLLR (0)
LLREYELIWSGSDDEMGVKTLLINKPDAPVLIDLRLRRE

>302A1ps ortholog Contig3838_Contig6523.13 82% identical to 302A1
MLTKLLKISCTSRQCTFAKPFEAMPGPRGPWGLGNLYNYMPIIGSYSFLR
LHQAGQDKYERYGAIVRETMAPGQDIVWLYDPKDIAKLLNERDCPQRRSH
LALAQYRRQRPHVYKTTGLLPTNGPEWWRLRSQLQKELSAPKSVRNFIPQ
VDGVTREFLTFLRESSDDGDAIDMLPKLTRLNLE (1)
LTCLLTFGARLQSFSP
EEQSPQSRSTHLMHAAETTNSCILPTDQGLQLWRLMETPSYRKLRQAQSY
MESVALKLMESSSSEQSSLISTYLQNPELDHSDVVGTAADLLLAGIDTTS
YASAFLLYHVARHPEVQQRLHAEARRVLPDPDQPLSADALRTDITYTRAV
LKESLRLNPISVGVGRVLNQDTVLSGYFVPKG (0) 
TTVVTQNMIACRLEQHFP
DPLLFQPDRWLQQRNALNPYLVLPFGHGMRACIARRLAEQNIHVLLLR (0)
LLRNFELIWRGGTDADLDVVTLLINKPDAPVMIELRSRSK*

>303a1m AC017306 12933-14444 no introns
MFYTVIWIFCATLLAILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVF
ARQYVNPYGFYGLKIGKDKVVIAYTNDAISEMMTNEDIDGRPDGIFYRLRTFNSRLGVLL
TDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHD
LTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPLLRFIAPNF
SGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKGMFSDQSL
LAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLP
YCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPES
FNPDRYLFDGHLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPE
EVPLEGATAAVKPYDIMLVAREQ

>303A1ps no introns Ajit Narang
MFYAVIWIFFATLLAVLLGGVRKPKRFPPGPRWYPIVGSALQISQLRCRLGMFCKVIDVL
ASRYVNPYGFFGLKIGKDKVVIAYTNDAISEMMTNEDIDGRPDGIFYRLRTFNSRLGVLL
TDGEMWVEQRRFILRHLKNFGFARSGMTDIVHNEATCLLQDLRAVVRREGGHQARIQMHD
LTSVYVLNTLWCMLSGQRYDPGSVEITELLETFFELFKNIDMVGALFSHFPLLRFIAPDY
SGYNGFVESHRALYSFMSKEIELHRRTYRSFDEPRDLMDSYLRAQEAGNDDKGMFSDESL
LAICLDMFLAGSETTNKSLGFCFMHLVLRPDIQERAYTEIKEVVGLERIPEWTRDRSKMP
YCEAITLEAVRMFMLHTFGIPHRAVCDTRLAGYEIPKDTMVIACFRGMLINPVDFPEPET
FNPERYLFDGQLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQHFKLVSIPGQMPE
EVPLEGATAAVKPYEVMLVARTPEQEC*

>304a1m AC008359 comp(80887-82836) also AC014292 AC009393
MITETLLTICAAVFLCLSYRYAVGRPSGFPP (1)
GPPKIPLFGSYLFMLIINFKYLHKAALTL
SRWYKSDIIGLHVGPFPVAVVHSADGVREILNNQVFDGRPQLFVAAMRDPGQDVR (1)
GIFFQDGPLWKEQRRFILRYLRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGG
YRVLLPLLFNPFSANAHFYIVYNECLSREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPW
IRHIWPEWSGYNKLNESNLFVRQFFADFVDKYLDSYEEGVERNFMDVYIAEMRRGPGYGF
NRDQLIMGLVDFSFPAFTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDR
KNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYRIPK (0)
DTIVVPSLYAFHSDARIWS
DPEQFRPERFLDADGKLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLG
PNDRLPDLSQNLNGLIISPPDFWLQLQDRH

>304a1ps D. pseudoobscura ortholog of Cyp304a1 M. Nooh
MLTELLLTICSAAFLYLSYRYAVGRPVGFPP (1)
GPPRIPFFGSYLFLLLINYKYLHKAALTL
TRWYKSDIIGLHVGKFPVAVVHSGEGVREVLNNQVFDGRPGIFLAAMRDPGDDVR (1)
GIFFQEGALWKEQRRFILRYLRDFGFGRRFDELELVIKEQITDMLDMIRNGPKYPHEHHLVKPGG
YRVQLPLLFNPFSVNSHFHVVYNERQSREDMAGLVRLVQMGMQFQRHADDYGRLLSIMPW
IRHVWPEWSGYKKLNESNQFMRQYFAEIVDRHIETYEEGSERNFIDLYISEMKSCPGHGF
NRDQFIMGLLDFSIPAFTAVGVQLTLLIQYLMLYPSVMERIQQEIEEVVGCGRLPTLEDR
KNMHYTEATIRESMRIETLVPSDVPHKALADTELLGYHIPK (0)
DTIVVPSLYAYHSDARVWS
DPEQFRPERFLDDQGELCLKLDVSFPFGAGKRLCAGETFARNMLFLMTAAMCQNFNYVLA
PGDQLPDLSKNQNGLIITPPDFWVQLENRRCG*

>305a1m D. melanogaster AC018013 comp(3457437224)
MSALIFLCAILIGFVIYSLISSARRPKNFPP (1)
GPRFVPWLGNTLQ (0)
FRKEASAVGGQHILFE
RWAKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLRTMGTRKGITC
TDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSV
LNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQFPWLRHVAPDRTGYNL
IQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLV
MTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAF
DYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPL
EFRPERFIDSAGKCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGES
PSMVLLPGITLTPKPYKVQFVKRT

>305A1ps ortholog from D. pseudoobscura (intron 2 is missing)
MSALIFLCAILIGFVIYSLIKSVQRPKNFPP (1) 
GPRFLPWLGNTLQFRKEARAVGG
QHILFGQWAQRYQSQLLGLKLGQEYVVVALGHEMVREVQLQEVFEGRPDN
FFLRLRTMGTRKGITFTDGKLWYEHRNFAMKQMRHVGYGRSQMESHIERE
AEELLLQLGRTEEAPIEPVTWLAHGVLNVLWCLIAGKRIASEGNSMLQRL
LDLMNRRSKLFDVCGGLLAQFPWLRHVAPDRTGYNLIRQLNTELYGFFMD
TIADHRRQLEKASDNEPVESDLIYAYLQEMRDQSSDSESSSFNETQLVMT
ILDFFIAGSQTTSNTINLALMVLAMRSDVQEKLFAEVSANVNSAKSDAFP
HLSRRESFDYMDAFIMEVQRFFHITPITGPRRALWPTQLGGYDIPKNATI
LINLRSVHLDEKHWVDPLQFRPERFIDVGGKCFKDEFFMPFGIGRRRCLG
DALARACIFSFLVRIVQHFCIVLPPGETPSMVLLPGITLTPKPYKVKFVKRS*

>306A1m D. melanogaster
MSADIVDIGHTGWMPSVQSLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGY
LPFLDARAPHKSLQKLAKRYGGIFELKMGRVPTVVLSDAALVRDFFRRDVMTGRAPLYLTHGIMGGF(1)
GIICAQEDIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVR (0)
LFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVSGV
VNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQR
QLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQL
RHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLHELLLPLGPSPTLEELEPLAYLRA
CISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPE
RFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLELPSGTEVDMAG
ESGITLTPTPHMLRFTKLPAVEMRHAPDGAVVQD

>306A1ps ortholog 66%
MSASFATASASASVFDWLPLSGHSFCLLVVPGLLILIILWLCDHQYDRVLGRPPPGPWGL
PWLGYLPFLSRRAPHKSLQALARRYGGIYQLRMGSVKAVILSDVTLVREFFRHEVMAARA
PLYLTHGIMGGY (1)
GIICAAGPIWKHQRRELIDWLKALGMTRRPGETRSRLEQRIGRGVDECVQ (0)
LYETDADVSPSSEFDPVPALQHTLGNIINDLVFGVTYERQDPDWLYLQRLQEEGVKLIGV
SGVVNFLPWLRRLPWNRRNICFLMEGKSRTHAIYDRIVESCENRLKELQEQYQEKQRQRQ
QQQDLQQYQQQDPQQDPEPESGSEQSLQQSPEQKEEKP (0)
KGEEEEDDDDDVYEPTCILE
HFLINRVPFSELYCDEQLRHLLADLFGAGVDTSLATLRWFLLYMAREQSSQRRLHELLLP
LSATPTLEELQPLAFLRACISEVQRIRSVVPLGIPHGAERDFTVGKYRIAAGSMIVSLQW
AIHMDPAVWPEPEQFRPDRFLNAEGHYSAPPQFIPFQTGKRMCPGDELARMMLTLFAGRI
LRRFHVEMVPGCDADMEGECGITLAPAPYKLRFTKLPPMELQVEEQPLVQA

>307a1m AC014810 comp(54284-52654) also AC007840 revised 9/8/2000
MLAALIYTILAILLSVLATSYICIIYGVKRRVLQPVKTKNSTEINHNAYQKYTQAPGPRP
WPIIGNLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKV
MSGRPDFIRYHKLFGGERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYMKMSQIGCE
EMEHWNRELGNQLVPGEPINIKPLILKACANMFSQYMCSLRFDYDDVDFQQIVQYFDEIF
WEINQGHPLDFLPWLYPFYQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPDRDFTD
ALLKSLLEDKDVSRNTIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEEIDAII
EEENRSINLLDMNAMPYTMATIFEVLRYSSSPIVPHVATEDTVISGYGVTKGTIVFINNY
VLNTSEKFWVNPKEFNPLRFLEP (2)
DNEKLQLKRNIPHFLPFSIGKRTCIGQNLVRGFGFLV
VVNVMQRYNISSHNPSTIKISPESLALPADCFPLVLTPREKIGPL

>307a1ps D. pseudoobscura ortholog of Cyp307a1 Jie Shen no introns
MSAVYSVLAILLAIIITSYIRILYKSRRRVCVAIRNGKSSTESEQIYEQAPGPRPWPIIG
NLNVLDKYRDNPFEGFTELAKKYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKVVSGRP
DFLRYHKLFGGERSNSLALCDWSQLQQKRRNMARRHCSPRESSSFYMQMSQIGCEEMEHF
IREIDAKMVPGEPFDVKTFLLRACANMFSQYMCSQRFDYDDEEFHKIVQYFDEIFWEINQ
GHPLDFLPWLYPFYRRHLNKIVHWSSTIRSFIMDRIISHRELDIDVDEPDSDFTDALLKS
LVEDKDVSRNTIIFMLEDFIGGHSAVGNLVMLALAYIAKNPQVGRRIQDEVDAVSSKGQR
KINLLDMHQMPYTMATIFEVLRYSSSPIVPHVATEDLVISGHGVTAGTIVFINNYVLNRS
REHWEDSHQFEPQRFLEPSTEGRRDSRGSDSGIESDQKEFQLRKNIPHFLPFSIGKRTCI
GQNLVRGFGFLLLANLLQGYNVSSGDPTTIRITPASLALPASCFPLLLTRRA*

>307a2pm AC019383 comp(3284-3706) AL078186
MLTSVFYVLFAIAITIILISYVFLLLKCKQKAFVVIGLLYQEKKYQCFDQAPGPHPWPII
GNINLLGRFQYNPFYGFGTLTKKYGDIYSLSLGHTRCIVVNNVDLIKEVLNKNGKYFGGR
PDFFRYHKLFGGDRNN (1?)

>307a2pps Contig3286_Contig7811B.fa.9 66% to D. pseudoobscura ortholog of 307A1
MFFSVCYLIIAIGITAIVISYILIIFKCNEKATVRIGLSNPEKAIRKFGQ
APGPQPWPIIGNLDLLGRFKSNPFEGLGALTKQYGDIYSLTLGHSRCLVV
NSLDLIREVLNKNGKFIGGRPDFIRYHKLFGGDRNN (1)
SLALCDWSNLQQKRRNLARRH
CSPRESSPYFNKMSHIGCNEINHLMRELNKTQPGKPFDIKKLILGASANM
FCQYMCSIRFDYNDKEFRRIVRYFDEIFWEINQGYSLDFLPWMLPFYKNH
TQKIVQWSTTIRKFILDRVIHQREEMLDLDEPENDFTDALLRSLKEDQNV
SRNTIIFMLEDFIGGHSAVGNLVMLALAYIAKNPMIGRRIEHEADIVTNK
GRRRINLYDMDAMPYTMATIFEVLRYSSSPIVPHVAMEDTAIAGFGVTRG
TIIFINNYMLNMSEKYWNSPDHFEPERFLDENYRR 
RRGSEGSDSGIEFEKDTH 
QLKKNIPHFLPFSIGKRTCIGQNLVRGFGFVLLANIVQSYNITSADISKININH
ESLALPADCFPLVLTPRA*

>308a1m AC015216 72624-74273 also AC012164
MLPLVLFILLAATLLFWKWQGNHWRRLGLEAPFGWPLVGNMLDFALGRRSYGEIYQEIYT (2)
RNPGLKYVGFYRLFNEPAILVRDQELLRQILVGRNFADCADNAVYVDHQRDVLASHNPFI
ANGDRWRVLRADLVPLFTPSRVRQTLPHVARACQLLRDQVPLGRFEAKDLATRYTLQVVA
SAIFGLDAHCLGIHMRVAHEPSRWLEWLAPLFQPSVWSLLETMSLLHTPRLGRLIGHR (2) 
YVPLPLQHWFRELVEARSGGDNLLQWLAESKRGLGKEELAGHATTLLLEGYETSAMLLAFAL
YELALNEDAQRRLHIELDEVAQRHAGNLIDPVALGELRYSEAALLEALRLHPAMQALQKR
CTKTFTLPDQKSGASSELKVHLGTVLVLPVQAIHL (2)
DPALYPAPNQFRPERFLNQPPMGCRFLGFGAGPRMCPGMRLGLLQTKAALTTLLQD
HCVQLADEDQCRVEVSPLTFLTASRNGIWLSFKRRTRRY

>308a1ps D. pseudoobscura ortholog of B. WU 
MLLLLLLLLLLLLFFLGTLWRRLAWSNSHWRRRVVSGPQGCPLVGNMASFALGQRSYGEVYEQIYR (2)
QHPELRYVGFYRLFNEPAILVRDQRLVREVLVGSSFLNCADNAVNVDAQRDVLATCNPFI
ASGDRWRILRADLVPLFTPSRLRQTLPHVAAACQQLQEFVGRRLTGERFEAKALATRYTL
QVIASAVFGLDAHCLCYDEDQEKGSQWLQRLLPLFQPSAWSLLETIALLHSSRLANILQHR (2)
YVPLSLQDWLCALVRARSGANNFLHWLGDKQGEQGDLAGHATTLLLEGYETSAMLLAFAL
YELSRNESAQRRVQTELEEVAQRHGGLLVGHAALAELRYAEAALLETLRLHPAMQALQKR
CTKSFTLPPQRSDTDTAVGSHGSIQVALGTVLVLPVQAIHM (2)
DPNLYSDPLKFQPERFMDTSPMGCRFLGFGAGPRMCPGMRLGLAQTKAAL
VTLLRDYSFSLADQAQDPVQVSPLTFLTASKHGIWLQLQKR*

>309a1m AC019891 comp(47437-49308) also AC009909
MFTLVGLCLTIVHVAFAVVYFYLTWYHKYWDKRGVVTAEPLTILGSYPGILINKSRSLILDVQDVYN (2)
KYKDKYRTVGTFITRQPQLLVLDPALAHEILVDKFSHFRDTITSSFVGHNPDD
KYVAGSPFFSAGDKWKRLRSENVGGLTPSRLKMAYSIWEQSGRKLVEYIERARREQGDIIETRD (0)
LAYRFTANAMADFIWGIDAGSLSGKVGEIGDFQKTSTDWSAHAFSSMIRFNKTLVA
IFVRKLFSMRFFTKATDEFFLRLTQDAVNLRQGGSGEGRTDYLSHLIQLQQRGNSIHDSV
GHALTVHLDGFETSGAVLYHMLYS (0)
LSEHHEEQEKLRSEILEALASEGQISYDQINNLPYLDQCFN (1)
ESLRLTTPIGFFMRICTKPTQINLGDDKTLDLEPGVTVMVPAYQYHHDNDIYPEA
SEFRPDRFENGAASVLTKRGCFLPFGDGPRICL (1)
GMRVGQLSVKTAIVHILSNYQVEQMKKVPLGADSGMGIFLNGDVELKYTKLQK

>309a1ps D. pseudoobscura ortholog of 309a1 L. Yang 76%
MWTTVGLLLGAVHVAFAAVYLYLTWHHKYWQKRGVLTAEPLTILGTYPGVLADKSRSLILDVQEVYN (2)
KYKEKHRAVGTFLTRQPQLLVLDPALAHEVLVDKFSHFRDTVTSSFVGHNPDD
RFVQVSPFFSAGDDWKRRRTESGGGITPNKLKMAFTIWEQSGKKLLEYIERVRQERGDIIETRD (0)
LAYRFTANTMADFIWGIDAGTLTGAVGETSPFQKTSTDWTINAFKSIIRFNKSLVA
PFLRKVLQMRFFTKTAEQFYLQLTRDALRLRHSGSGSDRTDYLSHLIQLQQRGITLTDAV
GHALTVLLDGYETSAAVLYHMLYT (0)
LSEHPEEQEKLRSELVEALAADEHLSYEQLNALPYLDQCLN (1)
ESLRLTTPIGFFMRICTKATQLDLGQGQVADIEPGASVMIPAYQFHHDDAFYPEA
SLFQPDRFENGAASVLTKRGCYLPFGDGPRICL (1)
GMRVGQLSVKTAILHILSQYQVEQTTKVPMDADTGLGIFLNGDVQLKYTKLQK*

>309a2m AC009909 45541-45982 also AC019977
MYILASLALILLHLLVLPIYLYLTWHHKYWRKRGLVTARPLTLLGTYPGLLTRKSNLVFDVQKIYD (2)
KYKGKHRAVGVFVTRQPQILVLDPELAHEVLVSNFRCYKDSLQSSYLRHAKWDK
YARLNPFWASGQSWRRLRTDAQAGISGSRLRQAYNIWEQGGQMLTEYMTQQVAEKNNILETRD (0)
LCFRYTAHVMADFIWGIDAGTLTRPMEQPNKVQEMASKWTSYAFYMLTLFMATIVAP
CSRLLLRFRFYPKETDEFFSNLTKESIELRLKAGDSTRTDYLSHLLQLRDQKQATHDDLV
GHALTVMLDGYDTSGTALLHALYY (0)
LAENPAVQQKLRVEILSCMASEKSLDFEKLSSLQYLEQVIY (1)
ESLRLSSLIPQYTKVCTLPTVIRLSESKSLDVEVGMTIMIPNYQFHHDKQYFPEP
EAFKPERFDNGAYQELMRKGIFLPFSDGPRICM (1)
GVPLAMLTLKSALVHILSNFQVVRGRDRLIPKGDSGFGVVLQGDVNLEYRRFFR

>309a2ps D. pseudoobscura ortholog of 309a2 S. Yu 79%
MYILVTLGLIVVHLLLLPLYVYLTWHHRFWRKRGLVTARPLTMLGTYPGLLTRTSNLVEDVQKVYD (2)
KYKGKHRAVGVFVTRQPQILVLDPELAHEILVLNFRCYKDSLTSSYIRHARWDK
YARRNPFWASGQSWRSLRTDAQAGISGHRLKQGYAIWEEGGRMLTSYMTDRIKAPHNLLETRD (0)
LCFRYTAHVMADFIWGIDAGTLSRPQEHPNKVQQMASKWTSHAFYMISVFMASIV
APFSRLLLRLRFYPKETDEFFSRLTKESIDMRLSAGNDITRTDYLSHLLQLREQKQASHD
DLVGHALTVMLDGYDTTGTALLHALYY (0)
LAENPAAQQKLRMEILQSLDADKSLGFEKLCALPYLEQVVY (1)
ESLRLSSLIPQYTKICTNATQIQLNESKTLEVEEGMTVMIPNYQFHHDRKYF
PDPETFKPERFDDAAHLELIRKGVFLPFSDGPRICM (1)
GMRLALLTLKSALIHILSDFQVVRGKKRLVPNGDAGFGVVLQGNVHLEYRRFVR*

>310a1m AC017690 comp(12877-14650)
MWLLLPILLYSAVFLSVRHIYSHWRRRGFPSEKAGITWSFLQKAYRREFRHVEAICEAYQ
SGKDRLLGIYCFFRPVLLVRNVELAQTILQQSNGHFSELKWDYISGYRRFNLLEKLAPMF
GTKRLSEMFGQVQKVGDHLIHHLLDRQGQGCPQEVDIQQKLRV (2)
YSVNIIANLIYGLDINNFEHEDHILTSYLSHSQASIQSF (2)
TLGRLPQKSSYTYRLRDLIKQSVELREDHGLIRKDILQLLVRFRNGNEVSGDKWQLEPIN (1)
DADKLLSIKRLAKVAEDLLKVSLDAVASTVTFTLLEIL
QEPLIVEKLRAEIKELSNENGQLKFEELNGLRYMDMCLK (1)
ETLRKYPPLPIIERVCRKSYS
LPNSKFTIDEGKTLMVPLLAMHRDEKYFSEPMKYKPLRFLQTANDVGQCEDKTKSNVFIGFGIGGSQCV (1)
GQNFAKLVIKVALIKLLQNFHLELDANQVKTLKVSHRPAPFIHTKDGLKVKLKRREINTKFYS

>310a1ps D. pseudoobscura ortholog Y. Zhuang 78%
MWLLLPILLYSVLFLAVRHIYSHWRRKGFPSERAGISWSFLHQAYRREFRHVEAICEAYQ
MGRERLLGIYCFFRPVLIVRNVELAQTILQQSNGHFNDLKWDYVKGYRRFNLLEKLSPIF
ATKRLSEMFTHVQRVGDHLISYLLDIEQAQGGALELDLQQMLRV (2)
YAINVIGNLIYGLDVNNFEQKDHILSSYVSAGHTSLQSF (2)
TLSRLPQKSSFTYRLRDLIKQGVEHREEHGLIRKDILQLLTRFRNGNDISGDKWQIDIDN (1)
EQDKLLSIKRVAKVAEDLLKVSLDSISSNITLTLFEI
LQEPLIVEKLQTEIKELSNENGSLKFEELDGLKYLDMCLK (1)
ETVRKYPPLPIIERICRKSY
TLPNTKFTIDEGKTLMVPLLAIHRDEKYFSEPMKYKPLRFLHSEKSGDCKSNAFIGFGIGGAQCV (1)
GQNFAKMVIKVALIKLLQNFHLELDATLAETIEISHQPAPFIRTKDGLKVRLKRREIKPKFYN*

>311a1m AC014186 2270-3910
MALWPLLLITLTIWILVRKWTLLRLGSSLPGPWAFPLLGNAQMVGKLRPE (1)
YIFLVFTELRDRFGATYRLRLGPQLWVFLHSAEETRQALHDPTLRKADTFMQLEPLIGNGLLISHGAHWT
RQRRLLTPAFQPQLLRSFAPAIGGHVERLVGRLGATRGAFLEVTEPLFACLLDAIV (1)
DTSMGAQLDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQM
ESVIEKRAKELLDMGEPAGRAHNLLDTLLLAKFEGQSLSRREIRDEINTFVFA (0)
GVDTTTAAMSFVLYALAKFPETQTRLRKELQDVALDETTDLDALNGLPYLEALIKEVLRLYTIVPTT
GRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPAFSY
IPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGINVSFLKQ

>311a1ps in D. pseudoobscura R. Aziz missing exon 1 in a seq gap
(1) IFLVFTELRDRFGATYRLWLGPQLWVFLHTAEETREALHDPTLRKAKTFLQLEPLIGNGL
LISHGSHWTQQRRLLTPAFRPTLLRSFAPSVAKHADRLIQRLEETRGSFLEVTDPLFACLLDAIV (1)
DTSMGEQLETQSVAHSPIIKAFHRSSQLLFKRMINPLLASDWVFKQTRLWRELSEQLQVIH
TLMDSLIDRRSAQLQQQGNEPRKALNLLDTLLLANIDGEPLSRKEIRDEINTFVFA (0)
GVDTTTAAMSFVLYALAMNPEAQDRLQEELRQLPPGISIDLDTLNELPYLDALLKEVL
RLYTIVPTTGRQTTRSTVIGGRTYCAGVTLWINMYGLAHDASYFPDPYVFKPERWMQETE
LQAEVPFSYIPFSGGPHVCIGRRYALLLMKLLTARIARAFQLELRLGQPELTLQAQMVLK
TREGIHLAFTKR*

>312a1m AC015424 57845-59744 also AC009369 AC007573 AC010003
MFWLGFGLLLLALSLYLLYVFERQSRIDRLTHKWPAPPALPFIGHLHILAKLVGPHPLRR
ATEMINEHLHDHRAKLWMGTKLYLVDCNPKDIQALCSAQQLLQKTNDYRVFENWLCEGLF
TSGFEKWSHRRKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGDQIDFLQLISCF
TLDTICETALGVSVGSQSSAKSEYLDAVKS (2)
ILVIIDKRLKNIFYRNSFIFKRTSHYKREQ
ELIKTLHGFTEGIIQKRIDEINQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKP
LTVKDIREEVDTIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISI
EQVRQLEFLEACIKETLRMYPSGPLTARKATANCTI (1)
NDFFIPKGSDVIISPIYMGRCKDF
FPDPMVFKPDRWAIGAEPKIEATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFEP
LGERQVKLKLNFVITLHTVEPYLCRAKNLD

>312a1ps ORTHOLOG S. Nance 73% 
MVVWLGLCLLLIVLSLYLLYAFERQTRIDRLTHNWPAPPSLPILGHLHILAKLVGPHPFR
RATELVNTHLKDHRGKLWLGTKLYLVDCNPKDIQALCSAQQMLQKTTDYKVFENWLCEGL
FTADYDKWFQRRKTLTPAFNYTMIKQFVQVFERQSRILLPRVAEYAESGKSVDFLDLISC
YTLDVICETALGVSVDAQSGKRSSYLEAVRE (2) 
VLHVIDYRLKNLFYRHSFIYRRTALFRRE
QELLKTLHGFTEGIVQERQHQFNLDEVNRNTMSTKDAEMDKRPALSFLDTLLQAKTPEGA
SLSVKEIREEVDTIIFGGFDLTATVLKFVMYNMTLHTDHQQQCREEIWQICGKDTKEPIT
IEQVQQLEFLEWCVKETLRMYPPAPLLTRRATANCQI (1)
NDFFIPKGNDVVISPMYMGRCKD
FFPEPLVFKPERWARGAEPKIEATTFIPFMTGARSCLGQRYAMVMIKSVMAHLLRSYRFE
PIGERQVKMKLNFVVTLHTVEPYYCRVRAVE*

>313a1m AC017740 comp(167857-169728) also AC007809 AC007928
MLTINLLLAVGALFWIYFLWSRRRLYFLMLKIPGPIGLPILGSSLENIITYK (1)
RKLSFRTKYLNKYGSTILTWMGPVPFIVTRDPKVVEDIFSSPDCHNKSQHIVNAITSCMGNGLLGKQ (1)
DPHWLDRRKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYVDKGEIDVVPEMLRWSFKIAA (1)
QTTMGSEVKHDEHFKNGSLVESFES (2)
LISHSTLNILMPLVQNRMISKICGYDKLRADNFSRIQKMLDN (0)
VVNKKVNPLPKTDSDPESNIVINRAMELYRKGDITYMDVKSECCIMIAAGYD
TSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHFGITYPDMQKLDYLERVIKETLRL
IPAIPITARETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNFLAENM
EQKHPYAYIPFARGKRNCI (1)
GSKYAMMSSKFALCRILRNYKISTSTLYKDLVYVDNMTMKLAEYPRLKLQRRG

>313C1ps D. pseudoobscura CYP313C1 313ax same as 313a3 ortholog except exon 5
MYSLHLWIAVGILAWIYFLWSRRRFYLLMLRVKGPVGYPFLGVAVEYLRNK (1)
HNMEQRSKQFQEYGPTNLTWIGSVPVLVTCEPNVVQDVLTSPHCLDKSKIACNPLRLICGPATFALN (1)
GSHWVERRKQMNPSFRHNVLMSFFPLFNEETKNLISLLETFVGQGEKKLLPEFINWSFRTSI (1)
QSTMGSDLKDNPSIMNGAIQKKISN (2)
LIEVTYYLITFPWLQNRAISTLFGFEKRKSEAMIHLNASLQS (0)
ILQEKLKTQGDESKESLASRNIVINRARDFLRSGDFSYEDVKSECILTI
VAGFETSAITVFNTLILLAMFPEYQETAFEELKDVFPHVGDFEVSYDDLQKLVYMDRVLN
ESLRLLPPLPLIPREVTEDLKLSNGILIPKGVTVAIDIFNTHRNKDFWGLGADTFNPDNF
LPEHIQERHPYVFIPFNRGKRNCA (1)
GRKYAEISIKIALAKILRNFRLSTSFRFEDLSFVDNIVLEFKEQPLLELQHRR*

>313C2ps D. pseudoobscura CYP313C2 313ay 48% to 313a1 (this seq downstream of MYSLH 
MITLQLWIAVGILAWIYFLWSRRRFYLLMLRVKGPVGYPFLGSVVGFLRNK (1)
RNIGLAGKVAEKYGPTFLTWMGTVPVLVTSEPNVIQDILTSPHCLDKSQTACNAIIMNSGPGILALR (1)
GSHWVERRRKMIPSFKKNVVMSFLPIFNEETNSLLSVLDTFVGQGEREILPNVLNWSFRTAY (1)
QTTLGSDVKANTSFKNGTLLKNFKY (2)
TMENTTLAILFPLVQNRIIAKLLGIEKRRTEATFIVNELTKS (0)
LIEEKMTNKPDENQESFAIRNTVISRVVEFLKSGEFSYEDAEGECSIMVGASFETTAVTV
FSTLTFLAMFPEYQDAAFVELKDVFPNAGDFEVSNDEIQKLVYLDRVLNESLRLIPAIPL
IARETSQEVKLSNGILLPKSLTLCLDIFHTHRNKDSWGPEADKFNPDNFLPENISKIHQY
AYIPFNKGKRSCI (1)
GMKYAEIAAKVALSKILRNYKLSTSFRTEDFVFIENLSIDFAKKPLLELQRRD*

>313a2m AC017371 4100-5929 AC007724 AL057969 AL067059 rev. 9/8/2000
MIVIQLLIAASLILWIRFLWSRRKLYMLMMQLPGRMGLPLLGNSVRYLIISR (1)
GRMSSRTTYMDKHGSTYMAWIGTTPIVITRDPKIAEKVLTSPFCINRSSQTTNALALSMGYGLLTLQ (1)
GSKWMARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLSDLIRWSFAIAT (1)
QTTLGTDVTKDDNFENDAILKTYQS (2)
MLRLTIINIFVPFVQNKIVSKLFGLEWLRRRDASAINKMINN (0)
ILDKKLNSNPENYCESELKTVIHRAIELFRNDEMSLMELGAECSSMVLAAF
ETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLR
LMPSVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEK
IHDRHPYAFIPFSKGKRNCI (1)
GWRYGLMSSKLALVKILRNYKLKTSFPYENLEFVDHMVIKLAQSPQLAFERRTL*

>313a3m D. melanogaster AC017371 18903720 also AC007724 chr3R:8,063,0238,064,850
MDTFQLLLAVGVCFWIYFLWSRRRLYMMHFKIPGPMGLPILGIAFEYLITYK (1)
RKMSIRTKYMDIYGSTCLVWVGPTPFVITRDPKIAEEIFLSPECLNRSSIFSKPVNSCTGDGLLSLE (1)
ASKWVDRRKNLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGEKKVRDDIVRWSFRIAT (1)
QTTVGTDVKKDASFKNDSVLKSYET (2) 
FMKIIVMNVLLPFTHNKIFSTLGGFETQKALAKSNVNKMIGT (0) 
IVDKKLMTKPESGSQPEITSVINKAIELHRNGEMSREEVQSECCSFVVAAFE
TTGDTVYHALILLAMFPEHQDTVYQELKELFPVAGDFEVTYDDLQRMVFLERVVNETLRL
IPSVPFTPRETIRDFRLSSGVVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPDHFLPDNV
RDRHPYAYIPFSKGRRNCI (1)
GWKYGLMSSKLALSKILRNCKVSTSFRYEDLEFVDNIGMELAQSPGLEFHRRT*

>313a4m AC017336 153877-155807 also AC007752
MLTWTLWCGLLFLLWIYFLWSRRRFYLLTLKIPGPLGYPILGMAHWLMRRE (1)
DILNAFGCFLDKHGPTIFSWLGPIPFMIVSDPQVVQDIFTSPHCVNKGIIYKAVDDGAGVGLFSLK (1)
DPRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEKDLIPLLQSFTLGIAT (1)
QTTMGSDVKDEESFRSNSLLGRYQC (2)
ILETMTDMCFSPWLNSRFCRQLAGKESHYYQAKTEIRQFIRK (0)
IIERKLAEDEMGALPSIQSNDKNLFLNLVTDLMRRGVFTLKNVEDESNIIVFGA
FETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQMVYLDLILNESM
RVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFLPH
NIQDKHPYAYIPFTKGIRNCI (1)
GWRYALISAKVTLAKLLRNYRFKTSFPFENLYFVEDITMKLKSVPLLELQKRT

>313a4ps ortholog D. pseudoobscura ortholog found by Yi Jin partial seq
MLTWTLWCGLLFVLWIYFLWSRRRFYLLTLKIPGPIGYPLLGMAHKLMRRE (1)
DILNEFGIYMAKHGPTIFSWLGPIPFMIVSEPQVVQDILTSPHCVNKGIIYKAVDDGAGVGLFSLK (1)
DPRWSVHRKLLNPAFGHKVLLSFLPIFNKETAQLLSQLDALPGGGEKDLIPLLQSLTLGIAT (1)
QTTMGCDVKSEENFMSNSLMERYQC (2)
CLETMTDMCFSPWLNSRWARQLSGKEANYYRAKTEIRAFIRK (0)
LIQKRLSEDTEDSIKSKDKNIFLNLATDLLRRGVFDWKNVEDESNIIVFGAFET
TANTVYYVLMLLAMFPQYQERAFEEIKSLFPNSGDFEVTYEDTQQMVYLDLVLNESMRVIPPVPVVSRQTSQDLTL
TNGIVVPKGVQIAINMFHMHRSKKIWGPEAESFNPDNFLPHNTRDKHPYA

>313A4bps paralog 73% to 313a4, first sequence in Contig837_Contig5345.19
MLTWSLWCGLLFVLWIYFLWSRRRFYLLTLKIPGPIGYPFLGMAHKLIHRE (1)
DILNEFGIYLAKHGPTIMSWLGPIPFVIASDPQVVQDILTSPHCVNKGIIYRAVDDGMGVGLFSLK (1)
DPRWSVHRKLLNPAFSHKVLLSFLPIFNKETGQLLSQFDDLPSKGEYNLIPLLQNFTMGITT (1)
QTTMGLDVKSEANFNSIVESYHC (2)
CLETITDMCISPWLHFKWVRQLTGREKNYHRSKTEIRAFLNK (0) 
LIQKRLAEDTEDSIKSKDKNIFLHVTTDLLKRGVFDLTNVEDESNQVVFGAFETT
AKTVYYVLMLLAMFPQYQEKVFEEIKSLFPDSGDFEVTYEDTQQMVYLDL
VINESMRVIPPIPLVSRQTSGDLTLSSGTVIPKGVQIMIDIFHMHRSKKI
WGPEAETFNPDNFLAHHTGGEKHPYAFIPFTKGIRNCI (1)
GWRYASISVKVILAKLLRNFSYKTSFKFEDLVFIEDVTIKLKTVPKLQIQKRT*

>313a5m D. melanogaster chr3R:8,058,5988,060,388
MLTLQIFEAFAIILCVYFLWSRRRFYIMMLKLPGPMGFPFIGLAFEYIRLK (1) 
RKIRLRTILFKIYGKTVLTWIGLTPVLVTCEPKILEDIFTSPNCSNRSSVVDKAISSCLGLGLLTLK (1)
NNHWNERRKLLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGGDINLLPELNKWSFKIAA (1)
QITMGDEVRNQANYQNGNLLESYKA (2)
LNNLIPIGVVMPWLRNKYLGKLFSYEKRRLEAATQSNAFIKD (0)
IIDKKLSSTDNSSEPALIDRILNLVRIGELSYDDVMGEFSNIIFAASDTLS
ITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLEKLVKLDRVLHETMRLIPA
VPLLIRQTSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPENKRAR
PPYSYLPFSKGKKTCL(1)
GWKLSLISAKLALAKILRNYMLSTTFLYKDLRFIDNTTMKLAEQPLLAVKRRI*

>313b1m AC007571 comp(104264-106046) also AC013225 intron 1 revised 2/11/2004
MLASIILSGWLLLAWLYFLWSRRRYYKVAWQLRGPIGWPLIGMGLQMMNPE (1)
TFLQYMDGLSRQFKAPFISWMGTSCFLYINDPHSVEQILNSTHCTNKGDFYRFMSSAIGDGLFTSSSPRWHKHR
RLINPAFGRQILSNFLPIFNAEAEVLLQKLELEGVQHGKRLEIYQILKKIVLEAAC (1)
QTTMGKKMNFQHDGSLCIFKAYNG (2)
LTEVCVKRMLSPWLYPDLIYRRSGLFRLQQKVVGILFGFIEQ (0)
LLEPIVSVVAANSNPDQQRSEMEMRGKSKAIFIEQVREHVERGQLSWQDVRDEANVTIAA (0)
TFETTSTALYFTILCLAMHPCYQEKLHKELVTELPPSGDINLEQLQRLEYTEMVINEA
MRLFAPVPMVLRSADQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVWGPLSRTYNPDA
HFGLDSPQRHAFAFVPFTKGLRMCIGYRYAQMLMKLLLARIFRSYRISTEARLEELLVKG
NISLKLKDYPLCRVERR

>313b1ps orth. 83% Drosophila pseudoobscura P. Khandelwal 
MLLGTCIILAIWLLLVWTYFLWTRRRYYKAAWQLKGPIGWPLIGMGLQMMNTE (1)
TFLQYMDKLSHKFKAPFVSWMGTSCFLYVNDPQTVEQVFNSNHCTNKGDFYRFLSSAIGDGLFTFSA
PRWHKHRRLINPAFGRQILCNFLPIFNAEAEVLLLKLDLEGVQHGKELEIYQILKKIVLEAAC (1)
QTTMGRKMNFQQDGSAAIFEAYNG (2)
LTEVCVKRMLSPWLPELIYRRSRLFVQQTKVVGVLRGFIEQ (0)
LLSPIVSVVDLDTSKEPLQQESKSKSKSIFIEQVREHVERGQLSWQDVRDEANVTIAA (0)
TFETTSTALYFTILCLAMHPTYQEKLHKELVAELPPNGNISLDQLERLSYTEMAINEAMR
LFAPVPMVLRSAAQDFPLRRDDGDFLIPRGTQIGIDIYNMQRDERVWGPLARTYNPDAHF
GPEAPSRHAFAFVPFTKGLRMCIGYRYAQMLMKLLLAKIFRSYRIITEARLDQLLVKGNI
SLKLSNYPLCRVKRR

>314a1m AC012699 22585-24723 also AC006496
MAVILLLALALVLGCYCALHRHKLADIYLRPLLKNTLLEDFYHAELIQPEAPKRRRRGIW
DIPGPKRIPFLGTKWIFLLFFRRYKMTKLHEVYA (1)
DLNRQYGDIVLEVMPSNVPIVHLYNR
DDLEKVLKYPSKYPFRPPTEIIVMYRQSRPDRYASVGIVNEQGPMWQRLRSSLTSSITSP
RVLQNFLPALNAVCDDFIELLRARRDPDTLVVPNFEELANLMGLEAVCTLMLGRRMGFLA
IDTKQPQKISQLAAAVKQLFISQRDSYYGLGLWKYFPTKTYRDFARAEDLIYD (2)
VISEIIDHELEELKKSAACEDDEAAGLRSIFLNILELKDLDIRDKKSAIIDFIAAGIET (0)
LANTLLFVLSSVTGDPGAMPRILSEFCEYRDTNILQDALTNATYTKACIQESYRLRPTAFCLARILEEDMELSGYSLNAG (0)
TVVLCQNMIACHKDSNFQGAKQFTPERWIDPATENFTVNVDNASIVVPFGVGRRSCPGKRFVEMEVVLLLAK (0)
MVLAFDVSFVKPLETEFEFLLAPKTPLSLRLSDRVF

>314a1ps ortholog 90.4% found by SunHong Kim
MAVILLLALALVLGCYCAIHRHKIGATYLKPLLKNTPLEDCYHATPVVPEQQKSRRRRSI
WDIPGPQRIPFLGTKWIFFVFFRRYKMTKLHEVYA (1)
DLNRRYGDIVLEVMPSNVPIVHLYK
REDLEKVLKYPSKYPFRPPTEIIVMYRQSRPDRYASVGIVNEQGPMWQLLRTSLTSSITS
PRVLQNFLPALNAVCDDFIDLLRARRDPDTLVVPNFEELANLMGLEAVCTLMLGRRMGFL
AADAKQPQKISQLAAAVKQLFISQRDSYYGLGLWKYFPTKTYRDFARAEDLIYD (2)
VISEIIDNELEEHKKSAECDDEGASGLRSVFLNILDLKDLDIRDKKSAIIDFIAAGIET (0) 
LANTLLFVLSSVTEEPSAMTRILSEFCEYRDTNILQDALTNATFTKAC
IQESYRLRPTAFCLARILEEDMELSGYSLNAG (0) 
TVVLCQNMIACHKDSNFQEAKQFSPERWIDPVTENFTVNVDSASIVVPFGVGRRTCPGKRFVEMEVVLLLAK (0) 
LVVAFDVSFVKPLETEFEFLLAPKTPLSLKLRDRAI

>315a1m AC015141 229-2538 also AC008307 AC007725 AC007648
MTEKRERPGPLRWLRHLLDQLLVRILSLSLFRSRCDPPPLQRFPATELPPAVAAKYVPIPRVKGLPVVGTLVDLIAAGGATH (2)
LHKYIDARHKQYGPIFRERLGGTQDAVFVSSANLMRGVFQHEGQYPQHPLPDAWTLYNQQHACQRGLFFM (2)
EGAEWLHNRRILNRLLLNGNLNWMDVHIESCTRRMVDQWKRRTAEAAAIPLAESGEIRSYELPLLEQQLYRWSIE (1)
VLCCIMFGTSVLTCPKIQSSLDYFTQIVHKVFEHSSRLMTFPPRLAQILRLPIWRDFEANVDEVLREGAAIID
HCIRVQEDQRRPHDEALYHRLQAADVPGDMIKRIFVDLVIAAGDT (0)
TAFSSQWALFALSKEPRLQQRLAKERATNDSRLMHGLIKESLRLYPVAPFIGRYLPQDAQLGGHFIEKD (0)
TMVLLSLYTAGRDPSHFEQPERVLPERWCIGETEQVHKSHGSLPFAIGQRSCIGRRVALKQLHSLL
GRCAAQFEMSCLNEMPVDSVLRMVTVPDRTLRLALRPRTE

>315a1ps D. pseudoobscura ortholog of 315a1 (sad gene) L. WEI
MNRKRTSLLHWLQQLLRTLLVRLLCQFKSKAGLTKATAGSNRCRSKGGEIVPIPRVKGLPVVGTLLDLIAAGGATH (2)
LHKYIDSRHRQYGPIFRERLGGTQDAVFVSSAPLMRGVFLHEGQYPQHPLPDAWTLYNQRHACQRGLFFM (2)
EGAEWLHNRRILNHLLLNGNLNWMDVHIESCTRQLVDQWRARTEEATAECDVPGSPSYYELPNLEQQLYRWSIE (1)
VLCCIMFGSNVLTCPKIQSALDHFTQIVHKVFEHSSRLMTFPPRLAQLLRLRIWRDFESNVNEVLREGAAIID
HCIGGEITEDGQLEHLEQLEQREETLFNRLQAAEVPGEMIKRIFVDLVIAAGDT (0)
TAFSSQWALFVLSREPQLQSRLARERVASESQLLHGLIKESLRLYPVAPFIGRYLPQDAHLGDHFVEKD (0)
TLVLLSLYTAGRDASHFEQPERVLPERWCVGRSHGSLPFAIGQRSCIGRRVALKQLHSLL
GKCTTQFEMQCLNEQPVDCMLRMVTVPDQTLRLALRPRSSE*

>316a1m AC017388 35538-37158 also AC010113 AC010557 AC010112
MILTATFICFCLASAFNYFRARRQRSLIKNLKGPFTWPLMGAMHKLLFLTPI (1)
NFFQRSTEYLTKYGTFSRCWVFHRLFIPLADLELSRQLLENDTHLETGYELMKDWLVGGVLMCQSEQW
QKRHSLISGLFDKGNLEQLIDLSRHQTEQLLQKLAKQADQKVFDIWYTVSPIVLDLMVMT
TCGAKPSEEYSKNLKD (2)
LSEIYRKRFLSLQSANRFNYWLSSPFMRKRQNRLIKRLNDEHNN
LMAMHQSQNQLKIENGLDIYQLRPIPLKDHKSLLEILLESKDPQLTGEEICGELNTCNYL
GYQLCSPALCFCLVTIARNPSVQQKCLDELNLAQIKDQGWDLEKLNYLDAVLHETMRLYP
PQVIVGRQLKKDFPY (1)
NAELPCGSEIYINLYELQRNEVRYPKANHFDAQRFLDSPPELLSY
SLGPRCCPARKFSMQLLKTLLAPILANFEVLPYGDEVRLDLRLVLGSSNGFQLALKPR

>316A1ps ORTHOLOG FOUND BY I. Moisini
MILTTTFLCFCVASAINYFRTRRQRSLIKNLGGPFSWPLMGAMHKLLFLKPQ (1)
NFFQRSHEYLAKYGAVTRLWVFHRLFMPLADLELAKQVLQSEQHLETGYELMRHWLGGGVLMCDKNQW
TQRHGLIGSIFNKGNMLPLTELCRQQAVLLQLTLADHAEQRDVFDAWTIVAPAVRDLMVL
TTCGVRPSEGYSEAFTC (2)
LTEIYRKRFLSLQSVNRFTFWVSSPLLRRRQAQLIKQLNDEHK
EHIDRFRRLQKQEEQLKAGNVVVDRIDPLPAQWHQSLLEILLAGNHNPEISDDDICAELN
TCNYLGYLLCSSALCFSLVTISRHPAVQQRCLEELRKAQREDQSWDVRRLPYLEAVLLET
LRLYPPQVIVGRHLTEDMPY (1)
NGTLPFGAEIYVNLFEMQRNEDRYLNASHFRAERFLESPP
EIYSFSMGPRCCPAKQFSMVLLKTLIAPILSNFELLPYGDAPRLDLRLSLGSSNGFQLALKPR*

>317a1m AC020477 126550-128106 no introns also AC009844 AL109349
MWIIFLIIGLLVLGLLVLLIIAARYQRDYWRYLDIPHERPKKLWPIIRQIMTQTLSTEAM
KAEHYSAIYKKFKGSGPFCGFYALLQPRALILDRELIRQIMIKDFWNFNDRGLYCNQKSD
PLSGDLYALRGESWKEMRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTLMSQPHSTV
HIQKIMRRYVLSSLAKCVFGLNAEQRKTYPLEDFEQMTELALNSHKHGYLMNLMMIRFPN
FCRMLRMRRTPKQAEEYFIKLLTSIVEQRETSGKPQKDYLQLLIDVKALEFITHQYEADK
ELGAHLQNELAAHAVVFLKAGYEQTANTLSYVLYELALHPELQVRVREEVKKAIERHDGH
ITHEGIKSLSFMGQVINETLRMHPITPYILRRTLNDYAVPDHPKYILVKELFLIIPTHAI
HHDPDIYPDPEEFKPDRWSGPRDSLQEQGTWFGFGVGARSCIGIQFAQLQLRLALALLLS
EYEFSLNTRKPLINLEDGIALTLMPLGVIEPGNEERAV

>317a1ps D. pseudoobscura ortholog of 317a1  V. Lamba 
MWIIFTIIGLVVLGLVILLIMAARYQRDYWHYLNIPHERPKKLWPIVRQIVTQSLSTEAM
KTAHYSALYSKFKGSGPFCGFYALLQPRALILDRELIRQIMIKDFWNFNDRGLYCNQKTD
PLSGDLFAMRGQSWKEMRQKLDPSLESDRMSWLFGSLYEEAEQLLLTVTSTLMKQPHSTL
HIQKLMRRYVLSALAKCVFGLDAQQRLKYSLEDFEKMTEMAVSSHKHGYLMNLMMIRFPN
FCRVLRMRRTPKQAETYFLTLLSDIVGQREASGVRHQDYLQLLVEIKALELITHQYQADK
ELNTHLQNELAAHAVVFLKAGYEQTANTLSYILYELAIHTDVQATVREEIKKAMERHDNN
LNYECVQSLAYLGQVINETLRVHPITPYILRRTLTDYQVPDHPTYMLVKELFLIIPTHAI
HHDPDIYPEPEEFKPDRWGGPRDSLQEQGTWFGFGVGARSCIGIQFAQLQLRLALALLLM
EYEFTLNSRKPLVSLDDGIALQLTPLGVIEPGTEERAV*

>318a1m AC014186 comp(968-207) AA803931 AA803220 AA821188 NM_167318 MHLNIALWACGALLAVLLAWQQRKCWRLIWQL
NGWRGVIQQPVLWLLLCINLHPN (1)
SILEKVSQYRVHFQRPLAVLVGTRVLLYIDDPAGMECVLNAPECLDKTFLQDGFFVRRGLLHAR (1)
GQKWKLRRKQLNPAFSHNIVASFFDVFNSVGNQMVEQFQTQTNLHGQAVKFTAAEDLLSRAVLEVSC (1)
LTIMGTPTNFTQLDDAHIAHSYKR (2)
LLEISAVRVVKPWLQIRLLHRLLAPELY
EESKKCAKLLEDFVGGIVRTKHRNWRLRDAVGGEKSGEDASNGWQRRIFIEQIFQLAANG
EMTLEEIMDEAQSMVLV (0)
SFETVSNSIMLALLCLATNKGDCQRRLLAEIRALVPDVGQ
VGLEQLQQLRYLDAFVSESLRLLATVPMNLRHVSRDFRLAGRQ
HETIVPQNSIVVLDTFNMQRDERWWGANARQFDPQRFLDQEEEQLSKGHNDSGSGEKRRQRD 
RRHSYSFLPFSNGLRSCI (1)
GRRYGLFIMKVFLVKLITNFDFQSDFELEKLQFVENISLKFKNADDILLTIQPKKEST*

>318A1ps ortholog found by C. Lancaster 78% 
MHLYVALWVCGTALALLLGWQQRKCWRLIWQLNGWRGVAQQPILWFLLCINLHPN (1)
SILERVTQMRKYFQRPLAILVGTRVLVYIDDPAGMESILNAPECLDKTFMQEGFFAKRGLLHAR (1)
GQKWKLRRKQLNPAFSHNIVASFFDVFNAVGNQMVEQFASQPHLHGRAVKFTDAEDMLSRA
VLEVSCLTVMGTPTNFTQTDDAHIASSYKR (2)
LLEISAIRVVKPWLQIDLLHRLLAPELYAEAEKCNQLLVEFVAGIVQSKHRNWQLRAAL
CEGAGEDSTAWQRRIFIEQIFQLAANGELTLQEIEDEAQSMVLV (0) 
SFETVSNSIMLALLCLATHKGDCQQRLRAEIASVFPGQGQGSTSDAPH
VGLEQLQQLRYLDAFVSEALRLLATVPMNLRHVSRDFQLPGREAVVPQNSIIVLDTFNM
QREEEWWGDNAKQFDPQRFLDQDDQPDQSPEGEDISGSSIPKTNGQQKQQKQQRRHSYSFLPFSKGLRSCI (1)
GRRYGLFIMKVFLVKLIVAFDFSSDFQLDQLQFVENISLKFNNVDDISLAIQP