>CYP1A1 canFam2 chr30:40791779-40794362 (-) strand
MFRLSIPISA SELLLASTVF CLVLWVVKAW QPRLPKGLKS PPGPWGWPLL GNVLTLGKSP  60
HLALSRLSQR YGDVLQIRIG STPVLVLSGL DTIRQALVRQ GDDFKGRPDL YSFSLVTDGQ  120
SLTFSPDSGP VWAARRRLAQ NALKSFSIAS DPASSCSCYL EEHVSKEAEV LLSRLQEQMA  180
EVGRFDPYRY IVVSVANVIC AMCFSKRYDH DDQELLSLVN LSNEFGEGVA SANPLDFFPI  240
LRYLPNPALD FFKDLNKRFY SFMQKMVKEH YKTFEKGQIR DVTDSLIEHC QDKRLDENAN  300
IQLSDEKIVN VVLDLFGAGF DTVTTAISWS LLYLVTNPNV QKKIQKELDT VIGRARQPRL  360
SDRPQLPYME AFILETFRHA SFVPFTIPHS TTRDTSLSGF YIPKGRCVFV NQWQINHDQK  420
LWGNPSEFQP ERFLTLDGTI NKALSEKVIL FGLGKRKCIG ETIARLEVFL FLAILLQQVE  480
FSVPEGTKVD MTPIYGLTMK HARCEHFQVR VRTEGAESSA A

>CYP1A2 dog NP_001008720 81% to CYP1A2 human 
MALSQMATEL LLASTIFCLV LWVVKAWQPR LPKGLKSPPG PWGWPLLGNV LTLGKSPHLA
LSRLSQRYGD VLQIRIGSTP VLVLSGLDTI RQALVRQGDD FKGRPDLYSF SLVTDGQSLT
FSPDSGPVWA ARRRLAQNAL NTFSIASDPA SSCSCYLEEH VSKEAEALLS RLQEQMAEVG
RFDPYNQVLM SVANVIGAMC FGHHFSQRSE EMLPLLMSSS DFVETVSNGN PVDFFPILQY
MPNSALQRFK NFNQTFVQSL QKIVQEHYQD FDERSVQDIT GALLKHNEKS SRASDGHIPQ
EKIVNLINDI FGAGFDTVTT AISWSLMYLV ANPEIQRKIQ KELDTVIGRA RQPRLSDRPQ
LPLMEAFILE IFRHTSFVPF TIPHSTTKDT TLKGFYIPKE CCVFINQWQV NHDQQVWGDP
FAFRPERFLT ADGTAINKTL SEKVMLFGMG KRRCIGEVLA KWEIFLFLAI LLQRLEFSVP
AGVRVDLTPI YGLTMKHTRC EHVQARPRFS IK

>CYP1B1 dog ACO52509 84% to CYP1B1 human
MATSLGPDAP LQPSALSAQQ TTLLLLLSVL AAVHAGQWLL RQRRRQPGSA PPGPFAWPLI
GNAAAMGPAP HLSFARLARR YGDVFQIRLG SCPVVVLNGE RAIRQALVQQ GAAFADRPRF
ASFRVVSGGR SLAFGQYSPR WKVQRRAAHS TMRAFSTRQP RSRRVLEGHV LAETRELVAL
LARGSAGGAF LDPRPLTVVA VANVMSAVCF GCRYSHDDAE FRELLSHNEE FGRTVGAGSL
VDVLPWLQRF PNPVRTAFRE FEQLNRNFSN FVLRKFLRHR ESLQPGAAPR DMMDAFILSA
GTEAAEGSGD GGARLDMEYV PATVTDIFGA SQDTLSIALQ WLLILFTRYP QVQARVQEEL
DQVVGRNRLP CLDDQPNLPY TMAFLYEGMR FSSFVPVTIP HATTTSACVL GYHIPKDTVV
FVNQWSVNHD PVKWPNPEDF DPARFLDKDG FIDKDLASSV MIFSVGKRRC IGEELSKMQL
FLFISILAHQ CNFKANPDEP SKMDFNYGLT IKPKAFSINV TLRESMELLD SAVQKLQAEE
DCQ

>CYP1D1P dog chr 1 87915406-87928215 (-) strand 57% to 1D1P hum
VIAELISKNGNFGLRSVITCVVVVVNVICILCFSMRYDPLL
EEFLRIHKMNAHLLETSSEANPADFMPCFLYRPL*IINAYQEFYQAPN*FIALHDHLTTYxx 
DHI*AIADALINACHNKYGTMEAATINDDEIISTMNGLFGA
GLETIAIFLFWGFLF
IIHFFQVKTWGWESVRFEHRKIIPYTEASIN*IFRYAPFLPLAIPH
STTEDTVQNGYFIPRKSCTFISMC*INHNQx
IWDNPKLFRSQRFINENRE
NESLENKMLIFGTGLWKCLTEDN
RNEICIFITSV 

>CYP2A13 dog NP_001032422 chr1:115840751-115846750 (-) strand
MLASGLLLVA LLACLTIIVL MSVWKQRKLG GKLPPGPTPL PFIGNYLQLN TEQMYNSLMK
ISERYGPVFT IHLGPRPVVV LCGHEAVKEA LVDQAEEFSG RGEQATFDWL FKGYGVAFSN
GERAKQLRRF SITTLRDFGV GKRGIEERIQ EEAGFLIEAL RGTRGAFIDP TFFLSRTVSN
VISSIVFGDR FDYEDKEFLS LLRMMLGSFQ FTATSMGQLY EMFYSVMKHL PGPQQQAFKE
LQGLEDFITK KVEQNQRTLD PNSPRDFIDS FLIRMQEEQN NPNTEFYLKN LVLTTLNLFF
AGTETVSTTL RYGFLLLMKH PDVEAKVHEE IDRVIGKNRQ PKFEDRAKMP YTEAVIHEIQ
RFGDMIPMGV ARRVIKDTKF REFLLPKGTE VFPMLGSVLR DAKFFSNPQD FHPQHFLDEK
GQFKKSDAFV PFSIGKRYCF GEGLARMELF LFLTTILQNF HFKSPQLPQD IDVSPKHVGF
ATIPRNYTMS FQPR

>CYP2A25 dog chr1:115809010-115815244 (+) strand 86% to CYPP2A6
MVASGILLVA LLTCLTVMVL MSVRRQWKLL EKLPPGPTPL PFIGNYLQLN IQQMSDSFMK 
ISKRYGPVFT IHLGPRRVVV LCGYEAVKEA LVDQAEEFSG RGAQATFDTL FKGY
GVTFSNGERAKQLRRFSITTLRDFGVGKRGIEERIQEEAGFLIEALRGTR
GAFIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSMGQ
LCEMFH 
SVIKYLPGPQ QQAIKELQGL EDFITKKVEQ NQRTLDPNSP RDF
IDSFLIRMQEEQNNPNTEFHLKNLVLTTLNLFFAGTETVSTTLRYGFLLLMKHPDVE
AKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQRFGDIIPLSLARRVIKDTKF
REFLLPK
GTEVFPMLGSVLRDAKFFSNPQDFHPQHFLDEKGQFKKSDAFVPFSI
GKRYCFGEGLARMELFLFLTTILQNFHFKSPQLPQDIDVSPKLVGLATIPRNYTMSFQPR

>CYP2B11 Canis familiaris (dog) NW_876270.1: 43114807-
MELSVLLLLALLTGLLLLMARGHPKAYGHLPPGPRPLPILGNFLQMDRKGLLKSFLRLQEKYGDVFTVYLGPRRT
VMLCGIDAIREALVDNAEAFSGRGKIAVVEPVFQGYGVVFANGERWKTLRRFSLATMRDFGMGKRSVEERIQEEA
QCLVEELRKTEGVLQDPTFFFHSMTANIICSIVFGKRFGYKDPEFLRLMNLFYVSFALISSFSSQMFELFHSFLK
YFPGTHRQVYNNLQEIKAFIARMVEKHRETLDPSAPRDFIDAYLIRMDKEKAEPSSEFHHRNLIDSALSLFFAGT
ETTSTTLRYGFLLMLKYPHIAERIYKEIDQVIGPHRLPSLDDRAKMPYTDAVIHEIQRFGDLLPIGVPHMVTKDI
CFRGYIIPKGTEVFPILHSALNDPHYFEKPDVFNPDHFLDANGALKKNEAFIPFSIGKRICLGEGIARMELFLFF
TTILQNFSVASPMAPEDIDLTPQEIGVGKLPPVYQISFLSR*

>CYP2B pseudogene dog UCSC browser chr1: 115742702-115752495
MALSALLLLTVFIGLLLLWVHPASRGCLPQGPWPLLFLGNILQIDHKGFLKTF
LRKKYGDVFTVYLGPRPVITLCGYRAVREALVD
NLIYTMLSLFFASTELQYHSLVWG
LLKNLMF
R*A
KKVEVEIDRIIGPH
TLEDLAKLPYTHAVIQEIQRFSDIIPLGIPHCVTKDTHFHSYHLPK
TTVYPILSSVLHDPCPFEKPEAIHPGHFLDAEGHFKTQEAFSPFSL
GRHLYLGKNLACSELFLFLTSVLQNFTLGSPKALEDIDITPQRNELAQMPPEFQLCFL

>CYP2 dog pseudogene UCSC browser chr1:115714139-115714674 (-) strand
EQGDPHTEFNQENLLSPTLDIFFFARMETTNTTS
RYGFQIPLKYPQV
GARVTQRVTGW*GERPCCLEDRAWVPNTGVVLPNILRLLDIILLRVPY
AVSQDTHFWGYHIPM

>CYP2C21 Canis familiaris (dog) chr28:11725179-11748107 (+) strand
MDLFIVLVICLSCLISFFLWNQNRAKGKLPPGPTPLPIIGNILQINTKNVSKSLSKLAENYGPVFTVYFGMKPTV
VLYGYEAVKEALIDRSEEFSGRGHFPLLDWTIQGLGIVFSNGEKWKQTRRFSLTVLRNMGMGKKTVEDRIQEEAL
YLVEALKKTNASPCDPTFLLGCAPCNVICSIIFQNRFEYDDKDFLTLLEYFHENLLISSTSWIQLYNAFPLLIHY
LPGSHHVLFKNIANQFKFISEKIKEHEESLNFSNPRDFIDYFLIKIEKEKHNKQSEFTMDNLIITIWDVFSAGTE
TTSTTLRYGLLVLLKHPDVTAKVQEEIHRVVGRHRSPCMQDRSCMPYTDAVVHEIQRYIDLVPNNLPHSVTQDIK
FREYLIPKGTTILTSLTSVLHDEKGFPNPDQFDPGHFLDENGSFKKSDYFMAFSAGKRVCVGEGLARMELFLLLT
NILQHFTLKPLVDPKDIDTTPIANGLGATPPSYKLCFVPV*

>CYP2C21-ie5b internal exon pseudogene chr28:11742314-11742482 (-) strand
QLYSAFPLLIHYLPGSHHVLFKNIANQFKFISEKI
KEHEESLNFSNPRDFIDYFLI

>CYP2C94P 57% to CYP2C19 chr28: 44111622-44132499 (+) strand 13 kb from CYP2E1
MALLGLPTFLVACVAFLLFIFVWRRGGTRGRLLPPGPPPLPIIGNILQVNLWDLPNSLSR
LAEQYGSVYSLRLDAHPVVVLHGYQALKEAL
xxxGSHFEAEEKFPIMDNALRGY
GIVFSHGERWKQMRRFTLMTLRNFGMGKRSIEDRIQEEAQHLMQALSHTQ
AQPVDPTFIFACAPCNMIFSILFNERLDYQDKELQQLIMLLNENISIASSFWTQ
LYNLWPSFIHYLPGRHQKFFKNIQNIKNFILEKVAQHQETLKPEQPRDYTDCFLDRMEE
EKHNPYSEFNLENLVAVGFNLFSAGTETVTNTLRLALLILLKHPEVE
GKIHEEIDRVVGRDRVPCMNDRAQMPYTDAVVHEVQRYINLIPSNLPHAVTQDTKFRQFYIPK
GTTVFPLLSSVLYDSKEFTNPQRFDPNHFLDENGSFQKSDFFVPFSI
GKRACLGESLARMEVFLFLTTTLQNFTLKPAVDQRELNIDPMCNGLLSIRQSFKLCFLPR

>CYP2D15 Canis familiaris (dog) D17397
MGLLTGDTLGPLAVAVAIFLLLVDLMHRRRRWATRYPPGPTPVP
MVGNLLQMDFQEPICYFSQLQGRFGNVFSLELAWTPVVVLNGLEAVREALVHRSEDTA
DRPPMPIYDHLGLGPESQGLFLARYGRAWREQRRFSLSTLRNFGLGRKSLEQWVTEEA
SCLCAAFAEQAGRPFGPGALLNKAVSNVISSLTYGRRFEYDDPRLLQLLELTQQALKQ
DSGFLREALNSIPVLLHIPGLASKVFSAQKAIITLTNEMIQEHRKTRDPTQPPRHLID
AFVDEIEKAKGNPKTSFNEENLCMVTSDLFIAGMVSTSITLTWALLLMILHPDVQRRV
QQEIDEVIGREQLPEMGDQTRMPFTVAVIHEVQRFGDIVPLGVPHMTSRDTEVQGFLI
PKGTTLITNLSSVLKDEKVWKKPFRFYPEHFLDAQGHFVKHEAFMPFSAGRRVCLGEP
LARMELFLFFTCLLQRFSFSVPAGQPRPSDHGVFTFLKVPAPFQLCVEPR

>CYP2E1 Canis familiaris (dog) chr28:44089031-44098811
MAALGITVALLVWMATLMLISIWKQIYSRWKLPPGPFPLPIIGNILQVDIKNVPKSLAKLAEQYGPVFTLYLGSQ
RTVVLHGYKAVKEVLLDHKNDLSGRGEVFAFQSHKDRGITFNNGPGWKDTRRLSLSTLRDYGMGKRGNEERIQRE
IPFLLEALRGTRGQPFDPTFLLGFAPFNVIADILFHKHFDYSDQTGLRIQKLFNENFHLLSTGWLQLYNIFPSYL
HYLPGSHRKVLRNVAELKDYSLERVKEHQESLDPTCSRDFTDCLLQELQKERYGTEPWYTLDNIAVTVADLFFAG
TETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGPSRVPAIKDRLEMPYMDAVVHEIQRFIDLLPSNLPHVANQD
TMFRGYVIPKGTVVIPTLDSVLFDKQEFPDPEKFKPEHFLNENGKFKYSDYFKAFSAGKRVCVGKSLARMELFLF
LSAILQHFNLKSLVDPKDIDLSPCTIGFAKIPPHYKLCVVPRSG*

>CYP2F1 dog NW_876313.1:NW_876270.1:43272128-43283098
MDGVSTAILLGLLALAFLFLILNSRGKSQLPPGPRPLPFLGNLLQLRSQDMLTSLTKSKEYGSVYTVHLGPRRVV
VLSGYQAVKEALVDQGEDFSGRGDYPVFFNFTKGNGIAFSNGDRWKVLRRFSVQILRNFGMGKRSIEERILEEGS
FLLAELRKTEGKPFDPTFVLSRSVSNIICSVIFGSRFDYDDERLLTIIRLINDNFQIMSGPWGEQLYNIFPSLLD
WIPGPHRRLFQNFGCMKDLIARSVRDHQDSLDPRCPRDFIDCFLNKMAQEKQDPHSHFHMDTLLMTTHNLIFGGT
ETVGTTLRHAFLVLMKYPKVQARVQEEIDRVVGRARLPALEDRAAMPYTDAVIHEVQRFADVIPMNLPHRVIRDT
PFRGFLLPKGTDIITLLNTVHYDPNQFLTPQEFNPEHFLDANQSFKKSPAFMPFSAGRRLCLGESLARMELFLYL
TAILQSFSLQPLGAPEDIDLTPLSSGLGNLPRPFQLRLRTR*

>CYP2F dog pseudogene UCSC browser chr1: 115820703-115830479 (-) STRAND 
DSTLVLNHSLCNAICSVFFSGCFDHENKHLVLI
LRQIPDHQQPLGQDW
DVQPLPSGWWPRPHHHLFQSWECLKHLITQCS*TSGLRLPSPRDSIHCFLANIAQ
GSDVITLLGTVCHNLSQFLMPQEFNCEHFVDASQSFKKIPAFMPFSA
GSRMCPCGLGKPLTHMEFFD
YLTVILHSFSLQPQGAPKDNDVTPIDS

>CYP2G2 dog chr1:115782146-115791970  90% to human 2G2P
MELGGAFTIFLALSLSCLLILIAWKRNSKGGKLPPGPTPIPFLGNVLQVRTDATFQSFMK
LREKYGPIFTVYMGPRPVVVLCGHEAVKEALVDRADEFSGRGELASIERNFQGH
GVALANGERWRILRRFSLTILRDFGMGKRSIEERIQEEAGFLLEELRKTK
GSPIEPTFFLSRTVSNVISSVVFGSRFDYEDKQFLKLLQMINESFIEMSTPWAQ
LYDMYSGIMQYLPGRHNRIYYLIEELKDFIASRVKINEASLDPQNPRDFIDCFLIKMHQ
DTNNPHTEFNLKNLVLTTLNLFFAGTETVSFTLRYGLLLMMKHPEVE
AKIHEEIDQVIGPHRIPSVDDRAKMPYTDAVIHEIQRLTDIVPMGVPHNVIRDTHFRGYLLPK
GTDVFPLLGSVLKDPKYFRYPDAFYPQHFLDEQGRFKKNEAFVPFSS
GKRICLGEAMARMELFLYFTSILQNFSLHSLVPPADIDITPRVSGFGNIPPTYELCLKAR

>CYP2J2  dog NW_876313.1 :19927114-19956047
MLAAVGSLAATLWAVLHLRTLLLGAVAFLFFADFLKRRRPKNYPPGPVPLPFVGNFFHLDFEQSHLKLQRFVKKY
GNVFSVQMGDMPLVVVTGLPLIKEVLVDQNQVFVNRPITPIRERVFKNSGLIMSSGQIWKEQRRFTLATLKNFGL
GRKSIEERIQEEAHHLIQAIEEENGQPFNPHFKINNAVSNIICSITFGKRFEYQDEQFQELLRLLDEVTCLETSM
RCQLYNVFPWIIKFLPGPHQKLFNDWEKLKLFIAHMTENHRRDWNPAEPRDFIDAYLKEMEKGNATSSFHEENLI
YSTLDLFFAGTETTSTTLRWGLLYLALNPEIQEKVQAEIDRVIGQSQLPGLAVRESMPYTNAFIHEVQRMGNIVP
LNVPREVTGDTTLAGYYLPKGTVIVTNLTALHRDPAEWATPDTFNPEHFLENGQFKKREAFLPFSIGKRVCIGEQ
LARSELFIFFTSLVQRFTFRPPDNEKLSLEFRTGLTISPVSHRLRAIPRS*

>CYP2R1 dog NW_876313.1:37769697-37744500
MRGPPGAEACAAGLGAALLLLLFVLGVRQLLKQRRPAGFPPGPSGLPFIGNIYSLAASGELAHVYMRKQSRVYGE
IFSLDLGGISAVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRKLAVNSFRCFGYG
QKSFESKILEETNFFIDAIETYKGRPFDLKQLITNAVSNITNLIIFGERFTYEDTDFQHMIELFSENVELAASAS
VFLYNAFPWIGIIPFGKHQQLFRNAAVVYDFLSRLIEKASINRKPQSPQHFVDAYLNEMDQGKNDPSCTFSKENL
IFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPTGKPSWDDKCKMPYTEAVLHEVLRFCNIV
PLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRNPEIFYPERFLDSSGYFAKKEALVPFSLGKRHCLG
EQLARMEMFLFFTALLQRLHFPHGLVPDLKPRLGMTLQPQPYLICAERR*

>CYP2S1 dog NW_876270.1: 43044442-43033913
MEAAGTWTLLLALLLLLLLLALARPRTRGHLPPGPPPLPLLGNLLQLRPGALYSGLLRLSKKYGPVFTVYLGPWR
RVVVLVGHEAVQEALGGQAEEFSGRGMLATLDGTFGGHGVFFSNGERWRQLRRLTTLALRDLGMGKREGEELIQA
EAQSLVEAFQGTVGRPFDPSLLLAQATSNIICSLTFGLRFPYEDKEFQAVVQAAGGTVLGVSSPWGQTYEMFSWL
LQHLPGPHTQLLSHLSVLATFAVQQVQRHKESLDTSGPPHDVVDAFLLKMAKEEQDPNTELTDKNLLMTVIYLLF
AGTVTVSTTVRYTLLLLLKYPQVQERVREELSRELGAGRAPGLGDRARLPYTDAVLHEAQRLLALVPMGVPRALA
RTTCFRGYTLPQGTEVFPLLGSVLHDPEIFDEPEEFNPDRFLDADGRFQKQEAFLPFSLGKRICLGEGLAHAELF
LLLTTILQAFSLESPSPPGALSLQPAVSGLFNIPPAFQLRVRP*

>CYP2T2 dog chr1:115897947-115901169 78% to mouse Cyp2t4
MFTALLLLLLLLLLLALARRSWGAQGTRTQGALPPGPTPLPLLGNLLQLESRRLDRALME 
LSGRWGPVFTVRLGPRPAVVLCGYSALRDALVLQADAFSGRGAMAVFERFTHGN
GIVFSNGLRWRTLRNFALGALKEFGLGTRTIEERILEEAACLLGEFQATT
GAPFDPRRLLGNAVSNVICSVVFGNRYGYEDPEFQRLLDLFNDNFRIMSSRWGE
MYNVFPTLLDWLPGPHHRIFQNFTELRVFISEQIQRHQQTRQPGKPRDFIDCFLDQMDK
EQNDPESHFQEETLVMTTHNLFFGGTETTSTTLRYGLLILLKYPEVA
AKVQAELDAVVGQSRTPRLGDREHLPYTNAVLHEIQRFISVLPLGLPRALTRDTHLHGYFLPK
GTFVIPLLVSSHRDPTQFKDPDCFNPTNFLDDKGEFQTNDAFMPFAP
GKRMCLGAGLARSEIFLFFTAILQRFCLLPVGNPANIDLSPQCTGLGNIPPAFQL
RLVAR

>CYP2U1 dog NW_8762971.1:28366254- 28348146
WLHRRTPVAAAGGAAGAGGHSSARGPQLLLADLARAYGAVFSFFIGRHLVVVLSDFRSVRAALVQQAEIFSDRPR
VPLVSLVTKEKGIVFAHYGPVWKQQRKFSHSTLRHFGLGKLSLEPKIIEEFKYVKEEMQKHGEDPFNPFPIVNNA
VSNIICSLCFGQRFDYTNSEFKKMLRLMSRALEICLNSQLLLVNICSWLYYLPFGPFKELRQIEKDITTFLKKII
KDHKESLNVENPQDFIDMYLLQVEEERKNNSNSSFNEDYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDIQEK
VQEEIERVIGADRVPSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSEKTLQGYTIPKGTVILPNLWSVHRDP
AIWEKPDDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFTFALPKDSKKPILTGRY
GLTLAPHPFNIVISKR*

>CYP2W1 dog NW_876319.1: 293563-287849 83% to human CYP2W1
MALLLLGILLLLGLWGLLRTCTRTPSSASRWPPGPRPLPLIGNLHLLRVSQQDQSLMELSEQYGPVFTVHLGRQK
TVVLAGYEAVREALVGTGPELADRPPIAIFQLIQGGGGIFFSSGARWRAARQFTIRTLHGLGVGRGPMADNVLQE
LRCLMGQLDCYRGQPFPLALLGWAPSNITFTLLFGRRFDYQDPVFVSLLSLIDEVMVLLGTPSLQLFNIYPWLGA
LFQLHRPVLRKIEEVRAILRTLLKARRPSMPGGGPVQSYMDALIQQGQGKDPQGLFAEANMVACTLDMVMAGTET
TSATLQWAALLMGKHPSVQCRVQEELDRVLGPGRAPQLEDQRSLPYTNAVLHEVQRFITLLPHVPRCMAADTQLG
GYLLPKGTPVIPLLSSVLLDKTQWETPRQFNPGHFLDAEGRFVKRAAFLPFSAGRRVCVGESLARSELFLLFAGL
LHRYRLLPPPGLSPDALDTTPAPAFTMRPPAQALCAVPRPGGYDQGDWGRV*

>CYP2AB1P dog AACN010195735.1 exons 8,9 75% to cyp2ab1 mouse 
KRELPPGSFPFPSENPWQLSFQLYPETL
GTIILPNLASVLLDPECWETPQQFNPGLFLDMGGNFLVNEAFLPFSA
GHQVGPGDHLALMELFLMFANPFRTFWFQLPEGSLG*DLQYIWGTL*PQPQKICAP 

>CYP2AC1   Canis familiaris (dog) XM_847513.1 
MSGFDSSIILPILSLLLIFLLNIKIFMTKASKQHFPPGPR
PLPIIGNLHILNlkrpyqtmleLSQKYGSIYSIQMGPKKVVVLSGYETVKDALVNYGD
QFGERSQVPIFERLFEGKGIVFSHGETWKTMRRFSLATLRNFGMGKRIIEDTIIEECQ
HLIWSFESHR GKPFEVKTVMNASVANVIVSVLLGKRFDYQDTQFLRLLTLIGENVKLI
GGPRIA
LFNMFPVLGFLLKSHKTVLRNRDELFAFIRMTFLDHQHKFDKNDPRSFIDAF
LVRQQE EKDTSTTYFSDENLVALVSNLFAAGTETTATTLCWALLLMMRYPEVQKKVCD
EITKVVGSAQPRITHRTQMPYTDAVIHEVQRFANILPTGLPHATTTNVMFKNYYIPKG
TEVITLLTSVLRDQTQWEKPDTFNPNHFLSSTGKFIKKEAFMPFSLGRRMCAGESLAK
MELFLFFTSLMQKFTFQPPPGVSHLDLDLTPDIGFTTRPMPHKICALLRA*

>CYP3A98   Canis familiaris (dog) XP_536868.2 GenPept
MDLIPSFSMETWLLLATSLVLLYLYGTYTHGVFKKLGIPGPTPLPFVGTALGYRKGFSVFDENCFRKYGRMWGFYDGRQPVL
AITDPDMIKTVLVKECYSVFTNRRSFGPVGFMKSAISLSEDEEWKRIRTLLSPTFTSGKLKEMFPIIGQYGDVLVRNLRKEA
EKGKSINLKDIFGAYSMDVITSTSFGVNIDSLNNPQDPFVENIKKLLKFDFLDPFFFSILLFPFLTPVFEVLNIWLFPKSVT
DFFTKSVKRMKENRLKDKQKHRVDFLQLMINSQNSKETDTHKALSDLELVAQSIIFIFAGYETTSTSLSFLMYELATHPDVQ
QKLQEEIDATFPNKALPTYDALVQMEYLDMVLNETLRLYPIAGRLERVCKKDVEISGVFIPKGTVVMVPTFTLHRDQSLWPE
PEEFRPERFSRKNKDSINPYTYLPFGTGPRNCIGMRFAIMNMKLALVRVLQNFSFKPCKETQIPLKLNAQGIIQPEKPIVLK
VEPRDGSVNGA

>CYP3A99   Canis familiaris (dog) XP_546969.2 GenPept
MDLIPSFSTETWLLLATSLVLFYLYGTYTHGLFKKLGIPGPTPLPFLGTVLGYRNGFCDFDEKCFRKYGRMWGFYDGRQPVL
AIMDPDMIKTVLVKECYSVFTNRRSFGPVGFMKSAITVSEDEEWKRIRTLLSPTFTSGKLKEMFPIIGQYGDMLVRNLRKEA
EKGKAISLKDIFGAYSMDVITSTSFGVNIDSLNNPQDPFVENAKKLLKFDFPDPFLLSIILFPFLTPLYEMLNIWLFPKKIT
DFFTKSVKRMKESRLKDKQKHRVDFLQLMINSQNSKEMNTHKALSDLELVAQSIIFVVAGYETTSTSLCLLMYELATHPDVQ
QKLQKEIDATFPNKAAPTYDTLVQMEYLDMVLNESLRLYPITGRLVRVCKKDVEISGVFIPKGTVVMVPTFTLHQDPDIWPE
PEKFQPERFSKKNKDSINPYTYLPFGTGPRNCLGMRFAIMNMKLALIKVLQNFSFKPCKETQIPLKLSSQGLIRPEEPIILN
VEPRDGSVRGA

>CYP4A36P (dog) 75% to CYP4A11 human, 73% to CYP4A22 human
MSVSVLSLTRPLDTVSGLLQLASLLGLALLLLKTAQLYQRRQWMLKAIQQFPSPPSHWFFGHKQE
FQTGLELQELKKRTEKYRCASPLWLWGSRVSLIVYDPDYMKMIPGRS
DPKSEGAYRFMAPWI
GYGLLLLNGEIWFQHRRMLTPAFHYDILKPYVRLMVDSVQVML
DKWEELLSQNSHLEIFEHVSLMTLDTIMKCAFRYQGNH*ADR
NFQSYIQAIKDLNYLVFSRMRNVFYQKDIFYWLTSEGRRNHKACQLAHEHT
DRVIKLRKAQLQDEGELEK
VRNKRHLDFLDISFFAK
MENGRGLSDKDLRAEVDTFKFEGHDTTASGISWILYALATHPEHQQRCREEIQSLLGDGASIT*
EHLDQMPYTTMCIKEALRLYLPVPTVGRELSKPITFPDGRSLPR
GFLVLLSFYALHHNSNVWPNPE
VFDPSRFAPDASRHSHAFLPFSGGSR
NCIGQHFAMKEMKVAVALTLLRFELAPDPFRIPVPTPKIVLMSKNGIHLHLRKLL*

>CYP4A36-de10b11b12b (dog, boxer) Chr15 adjacent to CYP4X1
GFLVLLSFYALHHNPNVWPNPE
VFDPSHFAPDASRHSHAVLPFSGGAR
XXXXXXXXXNELKVAVALTLLRFELAPDPFRIPVSTPKIVLMSKNGIHLHLRKLL*

>CYP4A37 dog 79% to CYP4A11 76% to CYP4A22
MSVSVLSLTRPLDTVSGLLQLASLLGLALLLLKAAQLYQHRQWLLKAVQQFPSPPSHWFFGHKQE 
FQTGQELQVFQKWTEKYPCACPRWLWGSRVSLVVYDPDYMKMILGRS
DPKAGGSYTFITPWI 
GYGLLLLHGETWFQHRRMLTPAFHYDILKPYVRLMADSVQVML 
DKWEELLTQNSHLEIFEHVSLMTLDTIMKCAFSYQGNHQADR 
NSQAYIQAIRDMNNLVFARVRNVFYQKDIFYGLTSEGRRNHKARQIAHQHT 
DRVIKLRKAQLQDEGELEKVRNKRHLDFLDILLFAK 
MENGKGLSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPEHQQRCREEIQSLLGDGASITW 
EHLDQMPYTTMCIKEALRLYPPVPGVGRELSKPITFPDGRSLPK 
GFLVSLSFYALHHNPNVWPNPE 
VFDPSRFAPDASRHSHAFLPFSGGSR 
NCIGKHFAMNELKVAVALTLLRFELAPDPFKIPVPTPRIVLMSKNGIHLHLRKLL

>CYP4A38    dog chr15: 16616983-16634891 78% to CYP4A11 76% to CYP4A22
MSVSLLSLTRPLDTVSGFLQVASLLGLALLLLKAAQFYWHRQWLLKAIQQFPSPPSHWFFGHRQE 
FQKGRELQELKKRTEKYPCASPRWLWGSRVSLVVYDPDYMRMILGRS 
DPKSDGSYRLMAPWI 
GYGLLLLNGEIWFQHRRMLTPAFHYDILKPYVRLMADSVQVML 
DKWEELLTQNSHLEIFEHVSLMTLDTIMKCAFSYQGNHQADR 
NSQAYIQAIRDLNNLVFARVRNVFYQKDIFYGLTSEGRRNHKACQLAHEHT 
DRVIKLRKAQLQDEGELEKIRNKRHLDFLDILLFAK 
MENGRGLSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPEHQQRCREEIQSLLGDGASITW 
EHLDQMPYTTMCIKEALRLYPPVPGVGRELSKPITFPDGRSLPR 
GFLVLLSFYALHHNPNVWPNPE 
VFDPSRFAPDASRHSHAFLPFSGGSR 
NCIGQHFAMNELKVAVALTLLRFELAPDPFRIPVPTPRIVLMSKNGIHLHLRKLL*

>CYP4A39 dog Chr15:16641912-16651675 77% to CYP4A11 76% to CYP4A22
MSVSVLSLTRPLDTVSGLLQLASLLGLALLLLKAAQLYQRRQWLLKAVQQFPSPPSHWLFGHKRE 
LQKGDELQLLLKWIEDFPCAFSRWIWGTEAEIMIYDPDYMKLILGRS 
DPKPDGSYKLMAPWI 
GYGLLLLNGETWSQHRRMLTPAFHYDILKPYVRLMADSVQVML 
DKWEELLSQNSHLEIFDHVSLMTLDTIMKCAFSYQGNHQADR 
NSQAYIQAIRDLNNLVFARMRNVFYQKDIFYGLTSEGRRNHKACQLAHQHT 
DRVIKLRKAQLQDKGELEKVRNKRHLDFLDILLFAK 
VENGRGLSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPEHQQRCREEIQSLLGDGASITW 
EHLDQMPYTTMCIKEALRLYPPVPNVGRELSKPITFSDGRSLPK 
GFLVLLSFYALHHNPNVWPNPE 
VFDPSRFAPGVSRHSHAFLPFSGGSR 
NCIGQHFAMNEMKVAVALTLLRFELAPDPFRIPVPTPKIVLMSKNGIHLHLRKLL*

>CYP4B1 dog XM_845151.1 86% to CYP4B1 human
MVSTLLSLSVSHLVLWATGLILVLGFLKLIRLLLRRQMLARAMD
SFPGPPTHWLFGHAQEIQQTGSLDKVVTWAHQYDYAHPLWLGPFLGFLNIYEPDYAKA
VYSRGDPKAADVYDFFLQWIGKGLLVLQGPKWYQHRKLLTPGFHYDVLKSYVAVFTNS
THAMLDKWEEKAREDKSFDIFCDVGYMALDSLMKCTFGKGDSSLGHRDSSYYSAVRDL
TLLMQQRIESFQYHNDFIYWLTPHGRRFLRACQAAHDHTDQVIRERKAALQDEKEQEK
IQNRRHLDFLDILLGARDENGIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALY
PQHQHRCREEVCEILGDRDSFQWDDLVKMTYLTMCIKESFRLYPPVPQVYRQLSKPVN
FVDGRSLPAGSLISLHIYALHRNSAVWPDPEVFDPLRFSSENVARRHPFAFMPFSAGP
RNCIGQQFAMNEMKVVTALCLLRFEFALDPLQLPVKMPQLILRSKNGIHLHLKSLRLG
SGK

>CYP4X1 dog XM_539622.2 74% to CYP4X1 human
MESSWLETRWARPLYLAFAFCLALGLLQAIKLYLRRLRLLRDLC
PFPAPPTHWFYGHQKLLQDGKIEKLEELVEKYPCAFPYWVGPFQAFFYIYDPDYAKTF
LGRTDPKSKYLYKFLIPCLGNGLVNLEGSKWFQHRCLLTPGFNVNILKSYIKVMAHSV
NTMLGKWEKICGTQDTVVEVFEHINLMTLDVLMKCAFSQETNCQISSNHDLYVKTTFE
ASKINFYRLYSFLHHHDIIFKFSPQGHRLQELVKILHQYTEKVIQDRKKLLKDEKKHG
NTQKRKDQDYLDIILSAQAENGNSFSDTDLRSEVNTFILAGHDTMAGSISWLLYHLAL
NPEHQERCRQEIRGILRDRSSITWDQLGEMSYTTMCIKESLRLAPPIPSISRELSKPI
TFPDGRSLPAGITVVLSIWGLHHNSAIWENPKVFDPLRFSQENSDQRHTHSFLPFSAG
PRNCIGQHFAMVKLKVAIALILLHFKVSPDPTRPLVFLHQIVLKPKNGVHLHLKKLP

>CYP5A1 dog XM_539887.2
MEVLSFLKLEVNGPMVTVALSVVLLALLKWYSTAAFSRLEKLGI
RHPKPSPFIGNLPFFCQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVE
NFHNFTNRMVSGLESKPVMDSVLFLRDKRWEEVRSVLTSAFSPEKLNEMTPLISQACD
LLLAHLKHYAESGDAFDIQRCYSCYTTDVVASVAFGTQVDSRRAPGDPFVKHCRRFFA
YSIPRPILVLILSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRR
DFLQLILDARHLATSLGVDSFDMVRQVFSSTDCTVGPSRPHQPRHLSQPLTLDEIVGQ
AFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLAEVDSFKEKYTALDYCSLQEGLPY
LDMVIAETLRIYPPAFRFTREAARDCEVRGQRIPAGAVVEVAVGALHRDPEYWPQPET
FNPERFKAEAQRRQQPFTYLPFGAGPRSCLGVRLGLLEVKLTLLQVLHQFRFEACPET
QVPLQLDSKSALGPKNGIYIKIVSR

>CYP7A1 dog XM_544091.1
MMTISLIWGIVVAVCCCLWLIFGMRRRQMGEPPLENGLIPYLGC
ALKFGANPLEFLRANQRKYGHVFTCRLMGNYVHFITNPLSYQKVLCHGKYLDWKKFHF
TTSAKAFGHRSIDPSDGNTTENINKTFIKTLQGDALNSLTEAMMENLQLVMRCPLVSK
SKTPAWVTEGMYSFCYRVMFEAGYLTLFGKDLTGQDAQKGLILNNLDHFKEFDKIFPA
LVAGLPIHVFKTAHHAREKLAEGLRHENLGKRDHISELVRFLNDMLSTLDDMDKAKTH
LAILWASQANTIPATFWSLFQMIRSPEAMKAATEEVNKTLENAGQKISLDGSPICLNQ
MQLNDMPVLDSLIKESLRLSSASLNIRTATEDFTLHLQDSSYNIRKDDIIAFYPQLVH
LDPEIYPDPLTFKYDRYLDENGKTKTTFYSNGIKLKYYYMPFGSGATMCPGRLFAVQE
IKQFLILMLSYFELELVESQVKCPPLDQSRAGLGILPPLNDIEFKYKFKHL

>CYP7B1 dog XM_544102.2
MNGHTSGSLQFSTVPSAWRTLGVLESEWTKKGESAAKRQKVTEL
QVRCEYNVNGDRAEMSAPPPSGGSTWAAIQWMGPSSTKEERGCDEQISPRRPGEPPLI
KGWLPYLGEALKLQKDPLGFLRTLQKQHGDTFTLFAGGKYITFILDPFQYQLIMKTHK
LSFRIFSNKLSRKVFSIKKLETTDDLSNDLHGCYHLLQGKSLDVLTETMMQNLKQVFE
LHLLKTTNWDMAHLLTFCSSIIFEITLKTIYGKSLAGNGEKFITELRDNFLKFDDKFP
YLISDIPIELLGNIKSIRKKLIKHLASEHLGKTQGWSEIVQMRQDVLEKYYTLEDFEV
GAHHLGFLWASVTNTIPTMFWAMYYLLQHPEAMAVLRDEIDHLLQSTGQKKGSGFPMH
LTREQLDNLVYLESTVLEVLRIRSFSSIIRFVQEDLTLHSETQDYCLRKGDLVALFPP
AIHYDPEIFEAPEEFRFDRFVEDGKKKTTFFKKGKRLKYYLLPFGIGTSKCPGRFLAV
VEIKQLLVVLLTYFDLELIDDKPVVANRSRLLLGVQHPASDVFFRYKVKT

>CYP8A1 dog XM_543043.2
MVTCFSFTVAGKGVRNRRVLMGAASGVLSGGETGQVVKLAMESE
SEEWALWGGTHMLGIKAPGEDQKRRPGEPPLDLGSIPWLGHALEFGKDAASFLTRMKK
KHGDIFTVLVGGRYVTVLLDPHSYDAVVWEPHSKLDFHAYAVFLMERIFDVQLPHYSP
SDEKAKMKPTLLHKDLQALTDSMYANLRTVLLGDTTEAGSGWHEISLLDFSYSCLLRA
GYLTLYGVEALPRTHESQAQDRAHSADVFHTFRQLDLLLPKLARGSLSAGDKDQACRV
KGRLWKLLSPARLATRAHRSNWLESYLLYLEEMGVSADMQARALVLQLWATQGNMGPA
AFWLLIFLLKNPEALAAVRGEFEQLLSRAEQPISQMTTLPQKLLDNMPVLDSVLSESL
RLTAAPFITREVMVDLAMPMADGREFSLRRGDRLLLFPFLSPQKDPEIYTDPEVFKYN
RFLNSDGSEKKDFYKDGKRLKNYSMPWGAGHNQCLGKAYAISSIKQFVFLVLVHLDLE
LINPDMEIPEFDLSRYGFGLMQPEHDVPVRYRTRP

>CYP8B1 dog XM_542738.1 84% to pig 8B1
MVFWGLVLGALLVVTTGCLYLLGVLRQRRPQEPPLDKGSIPWLG
HAMAFRKNMFEFLKHMWAKHGDVFTVQLGGQYFTFVMDPLSFGPILKDAQRKLDFVKY
AEKLVLKVFGYHSGQGDYRMIHSASTKYLMGDGLEDLNKTMLDSLSLVMLGPTGQSLD
SSCWHEDGLFHFCYNVLFKAGYLSLFGYTKDQEQDLRQAEELFVQFRKFDRLFPRFVY
SLLGPREWREVGRLQRLFHKALSVKRNLEKNGISRWISYMLQYLRERGVAPAMQDKFN
FMMLWASQGNTGPTSFWALLFLLKHPEALRAVREEATQVLGEARLKARQSFDFKVSTL
HHTPVLDSVMEETLRLGAAPTLLRVVHNDHILKMASGQEYLLRSGDIVALFPYLSVHM
DPDIHPEPTTFKYDRFLNPNGSRKVDFYKAGKKIHHYTMPWGSGVSICPGRFLATNEM
KLFVLLMVTYFDLELVDPNTPVPPVDPQRWGFGTTQPSHEVRFRYRLRPTS

>CYP11A1 dog XM_535539.2, 79% to CYP11A1 human
MLAKGLPLRSVLVKGCQPFLSTVWEGPGHPRVPTGDGASISTQI
PRPFSEIPTPGNNGWLNLYNFWREMGSQKIHYHQVQNFQKYGPIYREKLGSVESVYII
DPEDVALLFKFEGPTPERFCIPPWVAYHQYHQRPVGVLLKKSGAWKKDRLALNQEVMA
PEAIKNFIPLLDPVSQDFVKVLHRRIKQQGSGKFSGDISDDLFRFAFESITNVMFGER
LGMLEERVDPEAQRFIDAVYQMFHTSVPMLTFPPDLFRLFKTKTWRDHVAAWDVIFNK
AEIYTQNFYWELRQKRDVDNYPGILHRLLKSNKLLFEDVKANITEMLAGGVDTTSMTL
QWHLYEMARSLEVQEVLREEVLAARRQAQGNVSTMLQLVPLLKASIKETLRLHPISVT
LQRYLENDLVLRNYMIPAKTLVQVSTYAMGQDPTFFLNPSKFDPTRWLGKDKELIHFR
NLGFGWGVRQCVGRRIAELEMTLFLIHILENFRVEMQQLRDVGTTFNLILMPDKPIFL
TFRPFNQGPPQV

>CYP11B2 XM_846295.1 in a seq gap in the genome
MAFRAQARGWRAGPWLAL
SRAPTLGTRAAPAPRAVLPFEAVPRCPGNKWMRVLQIWRQQGSESLHLEMHRTFQELG
PIFR
YDVGGTHMVHVMLPEGMERLQRGESPQPDTSPW

>CYP11B1 dog XM_539192.2 73% to human 11B2, 72% to human 11B1
MPRLRPQDQKRSLVGRASLRPCASGSEAPIHLFRPPPPPRPPPP
PPALTPEPGFLASSRDSFSHDAIESPLQASGRDKRTVLTGDGGSIGMAFRAQARGWRA
GPWLALSRARALGTRAAPAPRAVLPFEAVPRCPGNKWMRVLQIWRQQGSESLHLEMHR
TFQELGPIFRYDVGGTHMVHVMLPEDVERLQRVESPQPWRPPLDPWLAYRQHRGHKCG
VFLLNGPEWRLNRLKLNPDVLSLQAVQKYIPMVDGVARDFSQALRARVLQNARGSLTL
DIRPSILYYTVEASSLALFGERLGLLGPSPSPASLHFLQALEAMLRSTAQLLYLPRGL
SRWTSARVWKEHFESWDYIVQYANEAIQRIYQELALGRPQHYSGIVGELLLRADLSPE
AVRANCIELTAGSVDTTAYPLWMTLFELARNPDVQHALRQESQGAQAGIAENPQTAVT
ELPLLRAALKETLRLYPVGISVDRQVGSDVVLQNYHIPAGTLVKVQLYSLGRNPSVFE
RPERYHPQRWLDGRGSGTRAPSLAFGFGVRQCLGRRLAETEMLLLLHHVLNNFLVETL
THEDVKMVYRFIMMPSTLPLLTFRAIH

>CYP17A1 dog XM_535000.2 78% to CYP17A1 human
MWELLVFLLFTLVYFLWPKSKCPNAKYPRSLPSLPLVGSLPFLPRDGHQHVSFFKLQKKYGPIYSFRMGTKTTV
MVGHHQLAKEVLIKKGKEFSGRPRVVTMDILSDNQKGIAFADHG
ASWQLHRKLALATFALFKDGNQRLEKIICQENSLLCDFLATQNGKSIDLSLPLFLAVT
NIICLICFNTSYKNGDPALEIIKNYNDGILDTLGRDHMIDIFPGLKIFPNKTLEKMRN
CVKMRDDLLNEILEKYKQEKFSSDSITNMLDILIQARMNSDDNNAGSDRDSKLLSDKH
ILISIGDIFGAGVETTTSVVKWTVAFLLHNPQLQKKIQEEIDQNVGFGRIPTMSDRSK
LILLEATIREVLRIRPAAPMLIPHKAIVDSSIGEFAVDKGTSVIINLWALHHNEKEWY
RPDQFMPERFLDATKSQLISPSLSYLPFGAGPRSCVGEILARQELFLVMAWLLQRFDL
EAPDDGQLPSLEGIPRVVFLIESFKVKIKVRQAWREAQAEGST

>CYP19A1 NM_001008715.1 86% to CYP19A1 human (called family 17 in Genbank)
MLLEMLNPMHYNITSMMPEVMPVATMPILLLTGFLLLVWNYEDT
SSIPGPGYCMGIGPLISHCRFLWMGIGSACNYYNKMYGEFMRVWICGEETLIISKSSS
MFHIMKHSHYSSRFGSKLGLQCIGMHENGIIFNNNPTLWKAIRPFFTKALSGPGLVRM
VTVCVGSIITHLDRLEEVSNELGYVDVLTLMRRIMLDTSNILFLGIPLDESAIVVKIQ
GYFDAWQALLLKPDIFFKISWLYKKYEKSVKDLKDAMEILIEEKRHRISTAEKLEDHM
DFATELIFAEKRGDLTRENVNQCILEMLIAAPDTMSVSVFFMLFLIAKHPKVEESIMK
EIQAVVGERDIRIDDMQKLKVVENFIYESMRYQPVVNLVMRKALQDDIIDGYLVKKGT
NIILNIGRMHRLEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRSCAGKYIAMVMMKVV
LVTLLRRFHVQTLQGECIENMQKKYGLSLHPDETNNLLEMVFVPRNSEKCLER

>CYP20A1 dog XM_545603.2
MGLALHGASEANGAAERALPC
ASRQAAGIPGITPTEEK
DGNLPDIVNSGSLHEFLVNLHERYGPVVSFWFGRRLVVSLGTVEVLKQHINPNKTSDP
FETMLKSLLRYQSGGANVSENHMRKKLYESGVTHSLQSNFALLLKLSEELLDKWLSYP
ESQHVPLCQHMLGFAMKSVTQMVMGSTFEDDQEVIHFQKNHGTVWSEIGKGFLDGSLD
KSTTRKKQYEDALMQLESILKKIIKERKGKNFSQHIFIDSLVQGNLNDQQILEDSMIF
SLASCIITAKLCTWAICFLTTSEEVQKKLYEEIDHVFGKDPITPEKIEQLRYCRHVLC
ETVRTAKLTPVSARLQDIEGKIDKFIIPRETLVLYALGVILQDPRTWPSPHKFDPDRF
DDESMMKTFSLLGFSGMQECPELRFAYMVATVLLSVLVRRLHLLSVEGQLIETKYELV
TSSKEETWITVSKRY

>CYP21A1 dog GenEMBL AB039881
MLLLGVLLLTVLAGARLLWGKWKLRGLHLPPLVPGCLHLLQPDL
PLHLLGLTQKLGPIYRLRLGLQDVEVLNSKRTIEEAMVRKWVDFAGRPQTPSYKLVSL
HHQDLSLGDYSLLWKAHKKLTRSALLLGIRSSMEPLVEQLTQEFCERMRAQAGTPVAI
QKEFSLLTCAIICHLTFGNKEDTLVHTFHDCVQDLMRTWEHWSIQMLDIIPFLRFFPN
PGLWRLKRALENRDHIVEKQLRQHKESMVAGQWRDMTDYMLQRVGRLRAEEGCGQLLE
GHVHMSVVDLFIGGTETTATTLSWAVAFLLHHPEIQQRLQEELDRELGPGASGSRIPY
RDPTRLPLLSATVAEVLRLRPVVPLALPHCTTRPNSISGYDIPEGMVVIPNLQGAHLD
ETVWERPQEFRPDRFLVPGASPRVLAFGCGARVCLGEPLARLELLVVLAQLLRAFTLM
PAAGTLPSLRPRARCGVNLSMQPFQVQLQPRGAGVLGRGQHP

>CYP24A1 dog XM_543059.2 88% to CYP24A1 human
MSCPIAKSRSLVALLQQLGHLGQPPRPVASAACAPPRPREVPLC
PPVEPGEAQNAAALRGPTNWPLLGSLLEILWKGGLKKQHDTLAEYHKKYGKIFRMKLG
SFDSVHLGSPCLLEALYRTESAHPQRLEIKPWKAYRDYREEGYGLLILEGEDWQRVRS
AFQKKLMKPVEIMKLDNKINEVLADFMGRIDELCDERGRIEDLYSELNKWSFESICLV
LYEKRFGLLRKNAGDEALNFIMAIKTMMSTFGRMMVTPVELHKSLNTKVWQAHTLAWD
TIFKSVKSCIDNRLEKYSEQPSTDFLCDIYHHNQLSKKELYAAVTELQLAAVETTANS
LMWILYNLSRNPHVQQKLLKEIQRVLPENQMPRAEDLRNMPYLKACLKESMRLTPSVP
FTTRTLDKETVLGEYALPKGTVLMLNTQVLGSNEENFKDSSQFRPERWLQEKKKINPF
AHLPFGIGKRMCIGRRLAELQLHLALCWIIRKYDIVATDHEPVEMLHLGILVPSRELP
IAFRQR

>CYP26A1 dog XM_844281.1
MGLSALLASALCTFVLPLLLFLAAIKLWDLYCVSSRDRSCALPL
PPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILL
GEHRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALQCYVPVIAEEV
GTCLQQWLSRGERGLLVYPQVKRLMFRISMRILLGCEPRLASGGDAEQQLVEAFEEMT
RNLFSLPIDVPFSGLYRGMKARNLIHARIEENIRAKICGLRTAQAGGGCKDALQLLIE
HSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKG
LLCKSNQDNKLDIEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGW
NVIYSICDTHDVADIFTNKDEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKI
LLKIFTVELARHCDWRLLNGPPTMKTSPTVYPVDDLPARFTHFQGEI

>CYP26B1 dog XM_540236.2
MLFEGLELVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKS
CKLPIPKGSMGFPLIGETGHWLLQGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENV
RKILMGEHHLVSTEWPRSTRMLLGPNTVANSIGDIHRNKRKVFSKIFSHEALQSYLPK
IRLVIQDTLRAWSSHPEAINVYQETQKLTFRMAIRVLLGFSIPEEDLGHLFEVYQQFV
ENVFSLPVDLPFSGYRRGIQARQILQKGLEKAIREKLQCTQGKDYSDALDILIESSKE
HGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPAVLEKLREELRAQGILHS
GGCPCEGTLRLDTLSRLHYLDCVIKEVMRLFTPISGGYRTVLQTFELDGFQIPKGWSV
MYSIRDTHDTAPVFKDVNVFDPDRFGQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLF
LKVLAVELASTSRFELATRTFPRITLVPVLHPVDGLSVKFFGLDSNQNKILPETEAML
SATV

>CYP26C1 dog XM_845174.1 partial, end in a seq gap, 91% to human
MFPWGPSCLSVLGAAGTALLCAGLLLSLAQHLWTLRWTLSRDRASALPLPKGSMGWPFFGETLHWL
VQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLG
SHTLLGAVGEPHRRRRKVLARVFSRAALQRLVPRLQGALRREVRSWCAARRPVAVYQAAK
ALTFRMAARILLGLRLDEVQCAELARTFEQFVENLFSLPLDVPFSGLRK
GIRARDQ
LHRYLEEAIAEKLHEDKVAEPGDALDMIIHSTRELGHELSVQELK
ETAGELLFAAFLTTASASTSLV

>CYP27A1 dog XM_848001.1
MGRSLPVSLLGARGAPAGLCPRGARAKAAIPAAVPATAETPGNG
PGARRLRTLEELPGPGQLRFLFQLLGQGYVLQLHKLQVLNKAKYGPMWVTHAGPQTHV
NLASAPLLEQVMRQEGKYPVRNDMELWKEHRDQQGLAYGPFTTEGHHWYQLRHALNQR
MLKPSEAALYTDALNEVVDDFMAHLSQLLAESPSGNQVSDMAHQFYYFALEAICYILF
EKRIGCLERPIPQDTVAFVRSVGLMFQNSVYVTFLPKWTRPLLPFWKRYLDGWNTIFS
FGKKLIDQKLKEIETQLQTKGPDEVEISGYLHFLLTRGQLSTREAMGSLPELLLAGVD
TTSNTMTWALYHLSKNPEIQAALHKEVVGVVPPGQVPQQKDFAHMPLLKAVLKETLRL
YPVVPINSRVITEKEIEVNGFLFPKNTQFVFCHYVVSRDPDIFPEPESFQPYRWLRKS
QLAAPGVHHAFGSVPFGYGVRACLGRRIAELEMQLLLSRLIQQYQVVLAPETGEVKSL
ARIVLVPNKKVSLHFQPRQC

>CYP27B1 XM_538254.2 88% TO HUMANS CYP27B1
MGLNRGSGKQARCSGEVLSSVASPNQAMTQALKLASRVFHRIHW
APKLGSSLGSRGSDSAPRSLADIPGPSTPVFLAELFCKGGLSRLHELQVQGVARFGPV
WLASFGKVRTVYVAAPALVEQLLRQEGPRPERCSFSPWAEHRRHRQRACGLLTAEGEE
GQRLRSLLAPLLLRPRAAARYAAPLADVVRDLVRRLRQQRGRGAGPPALVRDVAAEFY
KFGLEGTAAVLLGSRLGCLEAQVPPDTDAFIRAVGSVFVSTLLTMAMPGWLHRLVPGP
WGRLCRDWDQMFAFAQQHVERREAEVALRSEGKAAEDVGSGAHLTYFLLREELPAPSI
LGNVTELLLAGVDTVSNTLSWALYELARHPDVQTALHSEITAALGPGSSAHPSAAALS
QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIRVGDYIIPKNTLVTLCHYATSRDPAQFP
EPNSFRPARWLGEGPAPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPE
PGAAPIRPMTRTVLVPERSINLQFVDR

>CYP27C1 dog XM_540989.2 revised 85% to CYP27C1 human
MALWARILSTRAASAPRRGRPPAPAAQQQPRPQGARPPAGVRTRARA*DKGAVRAL
ASRAGGRDHGSRSLAA
MPGPRTLANLVEFFWKDGFGRIHEIQ
QKHTREYGKIFKSHFGPQFVVSIADRDMVAQVLRAEGATPQRANMESWQEYRHLR
GRSTGLISAEGEQWLKMRRVLRQRILKPRDVAIFSGEINQVIADLIKRIYILKSQAED
GETVTNVNELFFKYSMEGVATILYESRLGCLENSVPQPTVDYIEALGLMFSMFKTSMY
AGAIPRWLRPLIPKPWLEFCRSWDGLFKFSQIHVDNKLKDIQCHMDRGERVRGGLLTC
LFLSQELTLEEIYANMTEMLLAGVDTTSFTLSWAVYLLARHPQVQQTLYQEIVKNLGE
RHIPTAADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVVGGYLIPKGTQLALCHY
ATSYEDENFPRAKEFWPERWLRKGSLDRVDNFGSIPFGYGVRSCIGRRIAELEIHLAI
IQLLQHFEIKPSSWTKAVPAKTHGLLTPGGPIHVRFVNRK

>CYP39A1 dog GenEMBL XM_538946.2
MELISPTVIIILGCVALLLFLQRKNLRGPPCIRGWIPWIGAGFE
FGKAPLEFIEKARIKYGPIFTVFVMGNRMTFVTEEEGINVFLKSKEVNFELAVQNPVY
RTASIPKNTFLALHEKLYIMMKGKIGTFNLYQFTGQLTEELHEQLENLGTHGTMELNH
LVRNLLYPVTMNMLFKKGLFPRNEGKIREFYQHFQAYDEGFEYGSQMPECLLRNWSKS
KKWLLALFEKNIPDIKTYKSAKDNSMTLMQTMLDIVEMERKEEKSPNYGLLLLWASLS
NAVPVAFWTLAFVLSHPSIHKTIMEGVSSVFGTAGKDKMKVSEDDLKKLPLIKWCILE
AIRLRAPGIITRKVLKPVKILNYTVPSGDLLMLSPFWLHRNPEYFPEPELFKPERWKK
ANLEKHAFLDWFMAFGSGKYQCPGRWFALLEIQICIILILYKYDCSLLDPLPKQSFLH
LVGVQQPEGQCRIEFKQRK

>CYP46A dog XM_537552.2 94% to CYP46A1 human 
MSQVWRSTQDCIHGVSLGFLLGHLPYFWKKDEVCGRVLQDVFLD
WAKKYGPVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMYHAIQTVFGERLFGQG
LVSECDYERWHKQRRVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQD
MLTCTTMDILAKAAFGMETGMLLGAQKPLSRKVKLILEGITASRNTLAKFMPGKWKQL
REIRESIRFLRQVGKDWVQRRREALKRGEDVPADILTQILKAEEGAQDDEILLDNFVT
FFIAGHETSANHLAFTVMELSRQPEILARLQAEVDEVIGSKRHLDCDDLGRLQYLSQV
LKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPD
RFSPKAPKPRFTYFPFSLGPRSCIGQQFAQMEVKVVMAKLLQRLEFRLVPGQRYGLQE
QATLKPLDPVLCTLQPRGWQPAPPPPC

>CYP51A1 XM_532457.2
MLLLGLLQAGGSVLGQAMERVTGGNLLSMLLIACAFTLGLVYLI
RLAVGHLAPLPAGAKSPPYIFSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVG
KTFTYLLGSDAAALLFNSKNEDLNAEDVYSRLTTPVFGKGVAYDVPNPVFLEQKKMLK
SGLNIAHFRQHVSIIEKETKEYFQSWGESGEKNLFEALSELIILTASHCLHGKEIRSQ
LNEKVAQLYADLDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKNIFYKAIQKRRQSEE
KIDDILQTLLDSTYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQ
DKCYLEQKTVCGEDLPPLTYDQLKDLNLLDRCIKETLRLRPPIMTMMRMAKTPQTIAG
YTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCI
GENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTMIHTPENPVIRYKRRSK