>CYP1A1 NM_000499
MLFPISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPW
GWPLIGHMLTLGKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDD
FKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLE
EHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLV
NLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKG
HIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLV
MNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTR
DTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIF
GMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVKVDMTPIYGLTMKHACCEHFQM
QLRS

>CYP1A2 NM_000761
MALSQSVPFSATELLLASAIFCLVFWVLKGLRPRVPKGLKSPPE
PWGWPLLGHVLTLGKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSRLDTIRQALVRQG
DDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIASDPASSSSCY
LEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANVIGAMCFGQHFPESSDEMLS
LVKNTHEFVETASSGNPLDFFPILRYLPNPALQRFKAFNQRFLWFLQKTVQEHYQDFD
KNSVRDITGALFKHSKKGPRASGNLIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLV
TKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHSSFLPFTIPHSTTR
DTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTAINKPLSEKMML
FGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSVPPGVKVDLTPIYGLTMKHARCEHVQ
ARRFSIN

>CYP1D1P NT_008580.9|Hs9_8737 chromosome 9 Pseudogene 43% to 1A2
MILDLAVTPGEVTTSLIILVMVFVFVRALRSKGRKQVSPPGP*SFPIIENLLQLGDHPY  
LTLMEMRKKYGDVFLLKLGMVPVLVVNGMEMVKQVLHKDGEHFAGRPNMHTFSFLAEGKS 
LSFSVNYGESWKLHKKIASKAL*TFSNAEAKSSTCSCSLEEHVTEEISELVTVFVELTSK 
NGSFDPRNAITCVVANIVCALCFGKR*DHSDEEFLRIVKTNDDLLKASSAANPADFIPCL 
HYLPLKIINAPLEFYQALNGFIALHVQDHLATYGK
DHIRDITDALINVCHNKYAATKTDTLNDSEIISTVSDLFGA 
GFETVSTCLCWSFLYLIHYPEIQARIQEEI
RPPRFEDRKILPYTEAFVSEVFRHASFLPFTIPHS 
TTADTTLNGYFIPRKTCTFINMYQVNHDE 
TIWDNHSLFRPDRFLNENRELNKSLVEKVLIFGMGIRKCLGEDVARNEIFIFITTVLQQFK 
LKK*PRAKLDLTPTYGLVMRPKLYQLQAELHPSGSSSA* 

>CYP1B1 NM_000104
MGTSLSPNDPWPLNPLSIQQTTLLLLLSVLATVHVGQRLLRQRR
RQLRSAPPGPFAWPLIGNAAAVGQAAHLSFARLARRYGDVFQIRLGSCPIVVLNGERA
IHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHYSEHWKVQRRAAHSMMRNFFTRQP
RSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDD
PEFRELLSHNEEFGRTVGAGSLVDVMPWLQYFPNPVRTVFREFEQLNRNFSNFILDKF
LRHCESLRPGAAPRDMMDAFILSAEKKAAGDSHGGGARLDLENVPATITDIFGASQDT
LSTALQWLLLLFTRYPDVQTRVQAELDQVVGRDRLPCMGDQPNLPYVLAFLYEAMRFS
SFVPVTIPHATTANTSVLGYHIPKDTVVFVNQWSVNHDPVKWPNPENFDPARFLDKDG
LINKDLTSRVMIFSVGKRRCIGEELSKMQLFLFISILAHQCDFRANPNEPAKMNFSYG
LTIKPKSFKVNVTLRESMELLDSAVQNLQAKETCQ

>CYP2A6 NM_000762
MLASGMLLVALLVCLTVMVLMSVWQQRKSKGKLPPGPTPLPFIG
NYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRG
EQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDAL
RGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGIFQFTSTSTGQ
LYEMFSSVMKHLPGPQQQAFQLLQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ
EEEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRV
IGKNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVY
PMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELF
LFFTTVMQNFRLKSSQSPKDIDVSPKHVGFATIPRNYTMSFLPR

>CYP2A7v1 wild type AC008537.3 Exon 8 is different from U22029
MLASGLLLVALLACLTVMVLMSVWQQRKSRGKLPPGPTPLPFIGNYLQLNTEHICDSIMK
FSECYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGY
GVAFSNGERAKQLLRFAIATLRDFGVGKRGIEERIQEESGFLIEAIRSTH
GANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLSMMLGIFQFTSTSTGQ
LYEMFSSVMKHLPGPQQQAFKLLQGLEDFIAKKVEHNQRTLDPNSPQDFIDSFLIHMQE
EEKNPNTEFYLKNLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVE
AKVHEEIDRVIGKNRQPKFEDRTKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPK
GTEVFPMLGSVLRDPSFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIG 
KRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVVFATIPRNYTMSFLPR

>CYP2A7v2 NM_000764 = U22029 a CYP2A7/CYP2A18PC (exon 8) hybrid
MLASGLLLVALLACLTVMVLMSVWQQRKSRGKLPPGPTPLPFIG
NYLQLNTEHICDSIMKFSECYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRG
EQATFEWVFKGYGVAFSNGERAKQLLRFAIATLRDFGVGKRGIEERIQEESGFLIEAI
RSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLSMMLGIFQFTSTSTGQ
LYEMFSSLMKHLPGPQQQAFKLLLGLEDFIAKKVEHNQRTLDPNSPQDFIDSFLIHMQ
EEEKNPNTEFYLKNLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRV
IGKNRQPKFEDRTKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPK
GTEVFPMLGSVLRDLRFFSNPRDFNPQHFLGEKGQFKKRDAFVPFSIR
KRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVVFATIPRNYTMSFLPR

>CYP2A7_v1axdelta2a NM_030589 NP_085079.2 alternative splice
MLASGLLLVALLACLTVMVLMSVWQQRKSRGKLPPGPTPLPFIGNYLQLNTEHICDSIMKVSQ
GVAFSNGERAKQLLRFAIATLRDFGVGKRGIEERIQEES
GFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLSMMLGIFQF
TSTSTGQLYEMFSSVMKHLPGPQQQAFKLLQGLEDFIAKKVEHNQRTLDPNSPQDFID
SFLIHMQEEEKNPNTEFYLKNLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKV
HEEIDRVIGKNRQPKFEDRTKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFL
PKGTEVFPMLGSVLRDPSFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRNCFGEG
LARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVVFATIPRNYTMSFLPR

>CYP2A7 related Separate C-term on AC008537.3 minus strand missing exons 3, 6, 8
MLASGLLLVALLACLTVMVLMSVWQQRKSRGKLPPGPTPLPFIGNYLQLNTEHICDSIMK 
FSECYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGY 
GANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLSMMLGIFQFTSTSTGQ
LYEMFSSVMKHLPGPQQQAFKLLQGLEDFIAKKVEHNQRTLDPNSPQDFIDSFLIHMQE 
AKVHEEIDRVIGKNRQPKFEDRTKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPK
KRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVVFATIPRNYTMSFLP 

>CYP2A13 U22028
MLASGLLLVTLLACLTVMVLMSVWRQRKSRGKLPPGPTPLPFIG
NYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRG
EQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGKRGIEERIQEEAGFLIDAL
RGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGRFQFTGTSTGQ
LYEMFSSVMKHLPGPQQQAFKELQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ
EEEKNPNTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRV
IGKNRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVF
PMLGSELRDPRFFSNPQDCSPQHFLDEKGQFKKSDAFVPFSIGKRYCFGEGLARMELF
LFFTTIMQNFRFKSPQSPKDIDVSPKHVGFATIPRNYTMSFLPR

>CYP2A13_related AC058798.1 6 diffs with 2A13 probable seq errors
MLASGLLLVTLLACLTVMVLMSVWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMK
ISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYG
VAFNNGERAKHLPRFSIATLRGFGVGKRGIEEHIQEEAGFLIHSLRGTHG

>CYP2A18PN = CYP2A7PT U22030 and 2A7PC U22044 
MLASGLLLVALLASLTVMVLMSVWQQRKSRGKLPLGPTPLLFIGNYLQLNTEHICDSIMK 
ISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVTCRT 
WERTKPLRRFSIATLRDFGVGKRGIKE 
IQEKAGFLIKAV*GTRGSSIYPTFFLSRTTSNVISSIV 
FGDRFDYEDK 
KFLSLLCMMLESFQFTAPSTGELYEMFSSVMKHLPGPQQQAFKELQGLEDFIAKKVEHN
QCTLDPNSPRDFIDSFLIRMQ 

>CYP2A18PC new gene AC008537.2 first line = 2G1 seq.
QEEKNPNTEFYLKNLVLTTLNLFVGGTETVSTTLHYGFLLLMKHPEVE
AKVHEIDRVIGKNQQPKFEDRAKTLYTEAVIHEIQRFGDLLPMGVSRRVKKDTKFRDFFLSK
GIEVFPMLGSVLRDLRFFSNPRDFNPQHFLGEKGQFKKRDAFVPFSI
GRRNCFREGLARMELFLYLTTIMQNFRFKSRQSPKDIVVSPKHVGFVTIPRNYTKCYLP

>CYP2B6 AC023172.1 CDS (hIIB1) cryptic exon 3A = 18813-18856 (hIIB2)
MELSVLLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFL
RFREKYGDVFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIA
MVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKS
KGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFE
LFSGFLKYFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPKDLIDTYLLHMEKEK
SNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGP
HRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLIL
STALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFF
TTILQNFSMASPVAPEDIDLTPQECGVGKIPPTYQIRFLPR

>CYP2B6_allele, AF182277 5 amino acid diffs, two are = CYP2B6*6
MELSVLLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLL
QMDRRGLLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIA
MVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERTQEEAQCLIEELRKS
KGALMDATFLFHSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFE
LFSGFLKYFPGAHRQVYKNPQEINAYIGHSVEKHRETLDPSAPRDLIDTYLLHMEKEK
SNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGP
HRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLIL
STALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFF
TTILQNFSMASPVAPEDIDLTPQECGVGKIPPTYQIRFLPR

>CYP2B7P1 = M29873 (hIIB3) AC008537.2 91% to 2B6 missing last exon
MELSVLLFLALLTGLLLLLVQRHPNSHGTLPPGPRPLPLLGNLLQMDRRGLLKSFLR
FREKYGDVFTVHLGPRPVVMLCGVEAIREALVDNAEAFSGRGKIVIMDPVYQGY
GMLFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQDEAQCLIEELRKSKG
ALVDPTFLFHSITANIICSIIFGKRFHYQDQEFLKTLNLFCQSFLLISSISSQ
LFELFSGFLKYFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPRDLIDTYLLHMEK
EKSNPHSEFSHQNLIINTLSLFFAGTETTSTTLRYGFLLMLKYPHVA
ERVYKEIEQVVGPHRPPALDDRAKMPYTEAVIREIQRFADLLPMGVPHIVTQHTSF*GYTIPK
DTEVFLILSTALRDPHYFEKPDAFNPDHFLDANGALKKNEAFIPFSLGK

>CYP2C8 M17397
MEPFVVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQ
IDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPI
SQRITKGLGIISSNGKRWKEIRRFSLTNLRNFGMGKRSIEDRVQEEAHCLVEELRKTK
ASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNN
FPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFMDCFLIKMEQEKD
NQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRH
RSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLT
SVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLT
TILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV

>CYP2C8-de6b old name CYP2C60P NT_030059.8 + strand exon 6
2034065 EKDNQPLKFTIENLVGNVPDLFVAGTEMTSTTLRYGLLLLLKHPELT 2034205

>CYP2C9 M61857
MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEA
LIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGC
APCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMDMN
NPQDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSH
MPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSA
GKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVPPFYQLCFIPV

>CYP2C9-de1b NT_008769.11|Hs10_8926 lone exon 1 32kb upstream of 2C9 
MDPAVALVLCLSCLFLLSLWRQSSGRGRLLFGPTPLLIIGNILQLDVKDMSKSLTNVSMLYAPL

>CYP2C9-de2c3c old name CYP2C59P NT_030059.8 - strand exons 2,3
FSKVYVPVFTVYFDIKLVLELHGYEVVKEALIDHGEEFSGKGIFPVSKKS**G 
XXIIFSNGKRCKDIWLFLLMTLWNCRMVKRS
MEKHVQGEAQCLRQELRRTK

>CYP2C18 M61856
MDPAVALVLCLSCLFLLSLWRQSSGRGRLPSGPTPLPIIGNILQLDVKDMSKSLTN
FSKVYGPVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPV
AEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTN
ASPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNLMEKFNENLRILSSPWIQVCNN
FPALIDYLPGSHNKIAENFAYIKSYVLERIKEHQESLDMNSARDFIDCFLIKMEQEKH
NQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRN
RSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLT
SVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLT
TILQNFNLKSQVDPKDIDITPIANAFGRVPPLYQLCFIPV

>CYP2C19 M61854
MDPFVVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGNILQ
IDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPL
AERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTK
ASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNLMEKLNENIRIVSTPWIQICNN
FPTIIDYFPGTHNKLLKNLAFMESDILEKVKEHQESMDINNPRDFIDCFLIKMEKEKQ
NQQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRN
RSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLT
SVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLT
FILQNFNLKSLIDPKDLDTTPVVNGFASVPPFYQLCFIPV

>2C58P NT_008769.11|Hs10_8926 lone exons 1,2,3 between 2C19 and 2C9 
LDLAAVLMLCLSCLLLLSL*TQISGRGKLPSDSTPLQVIESILQMADKDICKSSSNLSTLYXXXX 
SLYFDMKLVLVLHGYEVLKKALIHHGEEFSGKGIFPVSKKXXXXXX
IIFSNRKPCKEIWPFLLMTLWNCGVVKRS
LGKHVQVEAHCIVWELRRTK

>2C62P AL138921 NT_030059 chromosome 10 50% to 2C8
LAMCVTCLIFFLVWKKSPSPTPLPTIGNRLQRNPKD
CISFQLAKEYSSVYTLYFGSWPTMVFHGYKAVKEALIDQGDKSLGRGHIPIIDDAQKRY
TSAQPFDSTFILASAPCNL
CSFLFKECFQYKNETFLSLMGLLNENVK
TTVLPLLSLVLFSYKQFPXXXXXXXGHFLDKNGCFNKTDYFLPFSLGK

>CYP2C-se1[7] 2C56P NT_022154.9|Hs2_22310 2C pseudogene fragment chr 2 exon 7
SKVQEETDHAVGRHWRPCMQDRSHMPYTEAMVHEVQRH*PHPTNVPHALTSDIKFRNYLLPK 

>CYP2C-se2[1:2] old name 2C61P NT_008583.11|Hs10_8740 
KGKLPHDLTSFLFVGNILQLNSKNLSKSITMLAKDYGPGFTVYFGIKPTVVV 

>CYP2C-se3[1] old name 2C63P NT_011512.5|Hs21_11669 chromosome 21 
CPSCLILLFLWNGSYAKGKLLPGPIPLPIV*NILPLRSMNTSKSISM 

>CYP2C-se4[1] old name 2C64P NT_011602.7|HsX_11759 2C pseudogene fragment chr X 
ASVDLAAVLVLFLSHFLFLSLWKQSSEREKLLPGPTPIRIIGNILELDLKDICKSLSD 

>CYP2D6 NM_000106
MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLG
NLLHVDFQNTPYCFDQ LRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRP
PVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACL
CAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESG
FLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFL
AEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQE
IDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGMTHMTSRDIEVQGFRIPKG
TTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLAR
MELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR

>CYP2D7P1 = CYP2D7P M33387 
MGLEALVPLAMIVAIFLLLVDLMHRHQRWAARYPPGPLPLPGLGNL LHVDFQNTPYCFDQ 
LRRRFGDVFSLQLAWTPVVVLNGLAAVREAMVTRGEDTADRPPAPIYQVLGFGPRSQ 
GVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFADQA 
GPPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLRE 
VLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEK 
AKGSPESSFNDENLRIVVGNLFLAGMVTTLTTLAWGLLLMILHLDVQ 
VRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIIPLSVTHMTSHDIEVQGFRIPK 
GTTLITNLSSVLKDEAVWKKPFRFHPEHFLDAQGHFVKPEAFLPFSA 
GRRACLGEPLARMELFLFFTSLLQHFSFSVAAGQPRPSHSRVVSFLVTPSPYELCAVPR*

>CYP2D7P2 = CYP2D7AP X58467 AL021878 comp(46171-50354)
MGLEALVPLAMIVAIFLLLVDLMHRHQRWAARYPPGPLPLPGLGNL LHVDFQNTPYCFDQ 
LRRRFGDVFSLQLAWTPVVVLNGLAAVREAMVTRGEDTADRPPAPIYQVLGFGPRSQ 
GVILSRYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFADQA 
GRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLRE 
VLNAVPVLPHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAKKEK 
AKGSPESSFNDENLRIVVGNLFLAGMVTTLTTLAWGLLLMILHLDVQ 
LRVQQEIDDVIGQVRRPEMGDQAHMPCTTAVIHEVQRFGDIIPLSVTHMTSRDIEVQGFRIPK 
GTTLITNLSSVLKDEAVWKKPFRFHPEHFLDAQGHFVKPEAFLPFSA 
GRRACLGEPLARMELFLFFTSLLQHFSFSVAAGQPRPSHSRVVSFLVTPSPYELCAVPR*

>CYP2D8P1 = CYP2D8P AL021878 comp(55779-60892)
MGLDALVPLAVTVAIFLLLVDLMQQHQRWTARYPPGPLPLPGLGNLLHVDFQNIYTFNQ 
LRHRFGDVFSLQLAWMPVVVLNGLAAVREALVTCGEDTADRPPAPIYQVLGIGPRSQ 
GVFLAHYGHAWREQRRFSVSTLRNLGLGKKSLERWVTEEAACLCAAFADQA 
RRPFHPNGLLNKAASNVIASLTCGCRFEYDDPRFLRLLDLAQKGLKEELGFL*E
MLNVVPLLLRIPGLAGKVLRSQKAFLTQLDELLTEHRMIWDPA*PPRDLTEAFLAEKEK 
AKGNPESSFNDENLRMVVADLFFAGMVTTSITLAWGLLLMILRPDVQ 
ARVQQIDNVIGQVW*PEMGDQARMPCTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPK 
GMMLFTNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKLEAFLPFSA 
GRRACLGEPLARIELFLFFTSLLQHFSFSVPTGQPRPSHSRVVGFLVTPSPYELCAVPR

>CYP2D8P2 = CYP2D7BP or CYP2D8BP X58468
MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYSPGPLPLPGLGNLLHVDFQNTPYCFDQ
LRRRFGDVFSLQLAWTPVVVLNGLAAVREAMVTRGEDTADRPPAPIYQVLGFGPRSQ 
GVILSRYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFADQA
GRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQ  EGSKEESGFLRE 
VLNAVPVLPHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAKKEK
AKGSPESSFNDENLRIVVGNLFLAGMVTTLTTLAW  GLLLMILHLDVQ
VRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQHFGDIVPLGVTHMTSRDIEVQGFRIPK
GTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSA
GRRACLGEPLARMELFLFFTSLLQHFSFSVAAGQPRPSHSRVVSFLVTPSPYELCAVPR* 

>CYP2E1 J02843
MSALGVTVALLVWAAFLLLVSMWRQVHSSWNLPPGPFPLPIIGN
LFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGD
LPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRK
TQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQLY
NNFPSFLHYLPGSHRKVIKNVAEVKEYVSERVKEHHQSLDPNCPRDLTDCLLVEMEKE
KHSAERLYTMDGITVTVADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIG
PSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPT
LDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLL
LCAILQHFNLKPLVDPKDIDLSPIHIGFGCIPPRYKLCVIPRS

>CYP2F1 J02906
MDSISTAILLLLLALVCLLLTLSSRDKGKLPPGPRPLSILGNLL
LLCSQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYP
AFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKRSIEERILEEGSFLLADVRKT
EGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDERLLTIIRLINDNFQIMSSPWGELYD
ILDPRFPSLLDWVPGPHQRIFQNFKCLRDLIAHSVHDHQASSPRDFIQCFLTKMAEEK
EDPLSHFHMDTLLMTTHNLLFGGTKTVSTTLHHAFLALMKYPKVQARVQEEIDLVVGR
ARLPALKDRAAMPYTDAVIHEVQRFADIIPMNLPHRVTRDTAFRGFLIPKGTDVITLL
NTVHYDPSQFLTPQEFNPEHFLDANQSFKKSPAFMPFSAGRRLCLGELLARMELFLYL
TAILQSFSLQPLGAPEDIDLTPLSSGLGNLPRPFQLCLRPR

>CYP2F1P AC008537.3 93% identical to 2F1
GEPFDPTFVLSRSRSNIICSVLFGSRFDYDDERLLTIIRLINDNFQIMSSPWGE
LYDIFPSLLNWVPGPHQRIFQNFKCLRDLIAHSVHDHQASLDPRSPRDFIHCFLTKMAE
KKEDPLSHFHMDTLLMTTHNLLFGGTETVGTTLRHAFLAFMKYPKVQ
AHVQEEINLVVGHVRLPALKDRAAMPYTDMVIHEVQRFADIIPMNLPHRITRDTAFHGFLIPK
GTDVITLLNTVHYDPSQFLTPQEFNPEHFLDANQSFKKSPAFMPFSAG
HRLCLGESLARMELFLYLTAILQSFSLQPLGAPEDIDLTPLSSGLGNLPRPFQLCLHPR

>CYP2G1P AC008537 missing exons 4, 5 and 6 
MELGGAVTIFLALRLSCLLILIAWKRMDKAGKLPPGPTPILFLGHLLQVRTDATFQSFMK
LREKYSPVFTVYMGPRPVVVLCGHEAVKEALIDQADEFSGRGELASIKQNFQGHG
VALANGERWRILRRFSLTILRDFGMGKQSIKERIQEEASYLLEEFQKTK
AKIHEEINQVIGPHRLPRVDDRVKMPYTDVVIHEIQRLVDIVPMGVPHNIIQDTQFRGYLLPK
GTDVFPLLGSVLKDPKYFRYPDAFYPQHFLDEQGRFKKNEAFVPFSSGRGK
RICLGEAMARMELFLYFTSTLQNFSLCSLVPLVDIDITPKLSGFGNITPTYELCLVAR

>CYP2G2P AC008962 comp(28700-40696) seq of gene has two in frame stop codons
MEMGGAVTIFLALCLSCLLILIAWK*MNKAGKLPPGPTPIPFLGNLLQVRTDATFQSFMK
LREKYSPVFTVYMGPRPVVVLCGHEAVKEALVDQADEFSGRGELASIKQNFQGHG
VALANGERWRIL*RFPLTILRDFGMGKRSIEERIQEEASYLLEEFRKTK
GAPIDPIFLLSRTVSNVISSVVFRSRFDYEDKQFLNLLRLINESFIEMSTPWAQ
LYDMYSGIMQYLPGRHNLIYYLVEELKDFIASRVKINEASFDPQNPRDFIDCFLIKMH
QDKNNPRTEFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLLMKHPEVE
AKIHEEINQVIGPHRLPRVDDRVKMPYTDAVIHEIQRLVDIVPMGVPHNLIRDTQFRGYLLPK
GTDVFPLLGSVLKDPKYFRYPDAFYPQHFLDEQGRFKKNEAFVPFSSGR
GKRICLGEAMDRMELFLYFTSTLQNFSLHSLVPPVDIDITPKLSGFGNIPPTYELCLVAR*

>CYP2J2 NM_000775 chr 1
MLAAMGSLAAALWAVVHPRTLLLGTVAFLLAADFLKRRRPKNYP
PGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITGLPLIKEALI
HMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQ
EEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEV
TYLEASKTCQLYNVFPWIMKFLPGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRD
FIDAYLKEMSKHTGNPTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQ
EKVQVEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPQNVPREVTVDTTLAG
YHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLENGQFKKREAFMPFSIGKRACLG
EQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRMGITISPVSHRLC

>CYP2R1 Mikael Oscarson AC090835.6 Homo sapiens chromosome 11
MWKLWRAEEGAAALGGALFLLLFALGVRQLLKQRRPMGFPPGPPGLPFIGNIYSLAASSE
LPHVYMRKQSQVYGE
IFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMG 
GLLNSRYGRGWVDHRRLAVNSFRYFGYGQKSFESKILEETKFFNDAIETYKGRPFDFKQL 
ITNAVSNITNLIIFGERFTYEDTDFQHMIELFSENVELAASASVFLYNAFPWIGILPFGK 
HQQLFRNAAVVYDFLSRLIEKASVNRKPQLPQHFVDAYLDEMDQGKNDPSSTFSKENLIF 
SVGELIIAGTETTTNVLRWAILFMALYPNIQ
GQVQKEIDLIMGPNGKPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVR 
GYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSL  
GRRHCLGEHLARMEMFLFFTALLQRFHLHFPHELVPDLKPRLGMTLQPQPYLICAERR* 

>CYP2S1 AC011510 one exon per line 78% to mouse 2s1 49% to 2B6 47% to 2A13
MEATGTWALLLALALLLLLTLALSGTRARGHLPPGPTPLPLLGNLLQLRPGALYSGLMR
LSKKYGPVFTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDGH
GVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTE
GRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQAVVRAAGGTLLGVSSQGGQ
TYEMFSWFLRPLPGPHKQLLHHVSTLAAFTVRQVQQHQGNLDASGPARDLVDAFLLKMAQ
EEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQ
KWVREELNRELGAGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQ
GTEVFPLLGSILHEPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSL
GKRVCLGEGLAKAEVFLFFTTILQAFSLESPCPPDTLSLKPTVSGLFNIPPAFQLQVRPTDLHSTTQTR

>CYP2T2P AC008537
RAQMRGSLPPRPRPLPLLGNL
QLQSGGLDRALHSLSGRWGRVFTVRLGPRPAVGLCGYAALRDALVLQADA 
VSGRGSMAVFERFTRGNGILFSNRPCWWTLRNFALGALKKFGLGTRTVEA 
RVLEEAACLLDEFQATIGAPFDPVRLLDNAVSNVICSLVFGNRYRYGDPE 
FLRLLNLFSDNFCIISSRWGESLMDWLPGPHHRIFRNFSE 
LRVISEQIQRHWQMRQPAEPRDFIDCLTRWVRHGQQDPESHFQE*TSVM 
TTHFFFGVTETTSTTLCYGLLILLKYLEVAAKVQELDPVVGWRPAPSL 
DYRVCLPYANAVLLEIQCFISVVPLGLPRTLTLDTHLHSHCLPKGTFVIP 
LLVTAHRDPTQFKDPDCFNPTNFLDKGKFQGNDAFMPFAPAKQMCLG 
TGLAHSGIFLFLTATLQRFCLLPVVRPGTINLTQCTGLGSVPPDFQLQPVAC 

>CYP2T3P NT_011109.13 + strand
MIAGIAALLLWLLVLVPAWWG*GGCRAQMRGSLPPRPRLLPLLGNLQLQSGGLDRALHS 
LSGRWGRVFTVRLGPRPAVVLCGYAALRDALVLQADAVSGRGSMAVFERFTRGN 
GILFSNRPCWWTLRNFALGAPKKFGLDTRTIEARVLDEAACLLDEFQATI 
GAPFDPVRLLGNAVSSVTCSCLREPLWLRGPGVPEVLNLLSDNFRIMSSKWGE 
SLMDWLPGPHHQIFQNFSELQVFISEQIQQHWHMRQPAEPRDFIDCLARWVRHG 
KQQDPESHFQEETLVMTMQLFFFFFFGGTETTSTTLC 
YGLLILLKYPEVA
AKGQELDPVVGQRPVPSPDDHVQWPYTNAVLLEIQRFISVVPRTLTLDTHLHSHCLAKG 

>CYP2U1 AC096564.3 missing last exon, last exon from AC000016.1
MSSPGPSQPPAEDPPWPARLLRAPLGLLRLDPSGGALLLCGLVALLGWSWLRRRRARGI
PPGPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLARVYGSI 
FSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVTKEK 
GVVFAHYGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFKYVKAEMQKHGEDPFCPF 
SIISNAVSNIICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNICPWLYYLPF 
GPFKELRQIEKDITSFLKKIIKDHQESLDRENPQDFIDMYLLHMEEERKNNSNSSFDEE 
YLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQ 
EKVHEEIERVIGANRAPSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENT
VLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIKKETFIPFGI 
GKRVCMGEQLAKMELFLMFVSLMQSFAFALPEDSKKPLLTGRFGLTLAPHPFNITISRR* 

>CYP2W1 AC073957.7 chromosome 7 clone RP11-449P15 40% to 2F1
MALLLLLFLGLLGLWGLLCACAQDPSPAARWPPGPRPLPLVGNLHLLRLSQQDRSLME 
LSERYGPVFTVHLGRQKTVVLTGFEAVKEALAGPGQELADRPPIAIFQLIQRGG  
GIFFSSGARWRAARQFTVRALHSLGVGREPVADKILQELKCLSGQLDGYR  
GRPFPLALLGWAPSNITFALLFGRRFDYRDPVFVSLLGLIDEVMVLLGSPGLQ  
LFNVYPWLGALLQLHRPVLRKIEEVRAILRTLLEARRPHVCPGDPVCSYVDALIQQGQ  
GDDPEGLFAEANAVACTLDMVMAGTETTSATLQWAALLMGRHPDVQ 
GRVQEELDRVLGPGRTPRLEDQQALPYTSAVLHEVQRFITLLPHVPRCTAADTQLGGFLLPK
GTPVIPLLTSVLLDETQWQTPGQFNPGHFLDANGHFVKREAFLPFSA 
GRRVCVGERLARTELFLLFAGLLQRYRLLPPPGVSPASLDTTPARAFTMRPRAQALCAVPRP* 

>CYP2AB1P = old 2D31P chr3q27.1 185030751-185015757 - strand build 33
MLSLLSGLALLAISFLLLKLGTFCWDRSCLPPGPLPFPILGNLWQLCFQLHPETLLQ
LAQSVFTVWVGPIPVAVLSGFQVVKEALVSNSEQFSGRSLTPLFQDLFGER
GIICSSGHTWRQKRRFCLVMI*GLGL
GKLALEVQLQKEAAELAEAFRQEQGRPFDPQVSIVRST
VRVIGALVFGHHFLLEDPIFQELTQAIDFGLAFVSTVWRRLYDVFPWALC
HLPGPHQEIFRYQEVVLSLIHQEITRHKLRAPEAPRDFISCYLAQISK 
AMDDPVSTFNQENLV*VVIDLFLGGTDTTATTLCWALIHMIQHGAVQG
TVQLELDEVLGAAPVVCYEDRKRLPYTX
AVLHDVQRLSSVMAMGAVRQCVTSTRVCSYPVSK
GTIILPNLASVLYDPECWETPRQFNPGHFSDKDGNFVANEAFLPFSAGHRVYPAD
QLAQMELFLMFATLLRTFRFQLPEGSPGLKLEYIFGGTWQPQPQEICAVPR

>CYP2AC1P = old CYP2C57P AC022650 62% to Cyp2ac chr6p12.3 49549276-49539652 
GIAFSHGETWKTMRRFSLTTLRNFGMGEWIIEDTIIEECQNLIQNFEFHR
GKPFEIKTIMNASVAKIIVLVLLGKWFDY
QDSQFLRLLALTGENVKFIGGLRIAVTVSLLFTFNF 
LFNMFLVLGFLLKSHK
TILRNRDELFSFIRMAFLDHHHKLDKNDPRNFTDVFLVTQQE
ENDTFADYFSDKKLVTLVNNLFTTGTETTASTLHWGILLVMRYPEVQS
KVHNEITKVVVSAQS*LAHRTQMTHTDAVI*EVQRFANILPTSLSHATTTNIFKNYCIPK
GTEVIILLASVARDQAQWEKPDTFNPEHFLNSKEKFIKREAFLPFQW
GRRMCAGESFA
RKELFLFFTSLLQ
KFTFQPLPGVSHLDLDLSLDVGFTT

>CYP3A4 J04449
MAVIPDLAMETWLLLAVSLVLLYL
YGTHSHGLFKKLGIPGPTPLPF
LGNILSYHKGFCMFDMECHKKYGKVCGFYDGQQPVLAITDPDMIKTVLVKECYSVF
TNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNL
RREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDP
FFLSIIFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMID
SQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEI
DAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWV
VMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMN
MKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDGTVSGA

>CYP3A4-ie1b NT_007933.10|Hs7_8090
LIPNLAVETWLLL 

>CYP3A5-de1b2b NT_007933.10|Hs7_8090  ALT EXONS 1 AND 2 FOR CYP3A5
MDLIPNLAVETWLLLAVSLVLLYL 
YGAHSHGLFKKLGIPGPTPLLFLGTTLSYHQ 

>CYP3A5_v1 NM_000777
MDLIPNLAVETWLLLAVSLVLLYLYGTRTHGLFKRLGIPGPTPL
PLLGNVLSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVF
TNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNL
RREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDP
LFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMI
DSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKE
IDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGS
MVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMN
MKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDSRDGTLSGE

>CYP3A5-de13c old name = 3A51P NT_007933.10|Hs7_8090  EXON 13 
IPLKLRLGGLLQPEKPIVLKVESRDGTVSG 

>CYP3A5_v2 = CYP3A5P1 L26985 cDNA alternative splice from the 3A5 gene
MDLIPNLAVETWLLLAVSLVLLYLYGTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMW
SSLFGPHYPSSYEALGGSCVRLLLCVTP**TRT*GCCVSYN*
GTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRR 
ICATTSTIKMQTHSVTMWLPPAVLQSQHGVCLFL*Q 
SLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKE
KRHHKIHYKMSLTAPCWRKPYPSGT*VCTFNYS 
IFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLS
IILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSK
ETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNK

>CYP3A5_v3 = CYP3A5P2 X90579 alternative splice from the 3A5 gene
MDLIPNLAVETWLLLAVSLVLLYLYGTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMW
SSLFGPHYPSSYEALGGSCVRLLLCVTP**TRT*GCCVSYN*
GTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRR 
SLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKE
KRHHKIHYKMSLTAPCWRKPYPSGT*VCTFNYS 
IFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLS
IILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSK
ETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNK

>CYP3A7 NM_000765
MDLIPNLAVETWLLLAVSLILLYL
YGTRTHGLFKKLGIPGPTPL
PFLGNALSFRKGYWTFDMECYKKYRKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVF
TNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNL
RREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPFVENTKKLLRFNPLDP
FVLSIKVFPFLTPILEALNITVFPRKVISFLTKSVKQIKEGRLKETQKHRVDFLQLMI
DSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKE
IDTVLPNKAPPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGV
VVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALV
NMKLALVRVLQNFSFKPCKETQIPLKLRFGGLLLTEKPIVLKAESRDETVSGA

>CYP3A7-de1b2b NT_007933.10|Hs7_8090 alt exons 1 and 2 for 3A7
XDLIPNLAVETWLLLAVSLVLHYL
YETHSHGLFKNLGIPGPRPLLFLGTTLSYHQ

>CYP3A43-de1b AC011904 alt exon 1 83% to 3A43 
MDLIPNFAMEMCVLLATSLVLLYL

>CYP3A43 AC011904 one exon per line
MDLIPNFAMETWVLVATSLVLLYI
YGTHSHKLFKKLGIPGPTPLPFLGTILFYLR
GLWNFDRECNEKYGEMWG
LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQM
PLGPMGFLKSALSFAEDEEWKRIRTLLSPAFTSVKFKE
MVPIISQCGDMLVRSLRQEAENSKSINLKE
DFFGAYTMDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLI
SLFPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRLKDKQK
HRVDFFQQMIDSQNSKETKSHK
ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK
APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPE
RFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQ
IPLKLDNLPILQPEKPIVLKVHLRDGITSGP

>CYP3A43-de4c6c old name = 3A52P and 3A53P AC011904 NT_033964.1|Hs7_34119
MIKTVLVKECYSVFPNWR
EMLLIIL*YGDVFLRNLRQKVEKGKPLTLR

>CYP3A-se1[2] old name = 3A54P NT_033967.1|Hs7_34122 chromosome 7 
LYRYGTCSHGLFKKMAIPGLTLLPF

>CYP3A-se2[5] old name = 3A55P NT_033967.1|Hs7_34122 chromosome 7 
LESGLIITKHEKWKRLRSVISPAFPSGELQEV

>CYP4A11 NM_000778 12 exons 
MSVSVLSPSRLLGDVSGILQAASLLILLLLLIKAVQLYLHRQWLLKALQQFPCPPSHWLFGHIQE
LQQDQELQRIQKWVETFPSACPHWLWGGKVRVQLYDPDYMKVILGRS 
DPKSHGSYRFLAPWI 
GYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVML 
DKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDR 
NSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHT 
DQVIQLRKAQLQKEGELEKIKRKRHLDFLDILLLAK 
MENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITW 
NHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKG 
IMVLLSIYGLHHNPKVWPNPEV 
FDPSRFAPGSAQHSHAFLPFSGGSR 
NCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRRLPNPCEDKDQL*

>CYP4A22 new 4A11 like sequence AL390073.5 95% identical to 4A11 
MSVSVLSPSRRLGGVSGILQVTSLLILLLLLIKAAQLYLHRQWLLKALQQFPCPPSHWLFGHIQE
FQHDQELQRIQERVKTFPSACPYWIWGGKVRVQLYDPDYMKVILGRS
DPKSHGSYKFLAPRI
GYGLLLLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVML
DKWEELLGQDSPLEVFQHVSLMTLDTIMKSAFSHQGSIQVDR
NSQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAHQHT
DQVIQLRKAQLQKEGELEKIKRKRHLDFLDILLLAK
MENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDGASITW
NHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKG
IMVLLSIYGLHHNPKVWPNLE
VFDPSRFAPGSAQHSHAFLPFSGGSR
NCIGKQFAMNQLKVARALTLLRFELLPDPTRIPIPMARLVLKSKNGIHLRLRRLPNPCEDKDQL*

>CYP4A-se1[12] CYP4A26P AL731892.5 76% to 4A11 C-term upstream of 4A11
TCIGKKFAMNEL 
KVAMALTLLRFELLPDPTRIPVGIP*ILLKFKSGIHLHLRRV 

>CYP4A-se2[1] NT_04852.13 - strand exon 1 new
MSVSVLNPNRLPDGVSGLLQGASLLSLLLLLLKAAQP*LHR

>CYP4A-se3[12] CYP4A27P AL731892.5 67% to 4a11 C-term upstream of 4A26P
NCIGKQFAMNELKVALTLLNFKLFSDPASIPILLPQMVLKFNNGIHLHVKRL

>CYP4A-se4[2] NT_04852.13 exon 2 - strand
XXXDQELKQFQKWVDF*IYPKRDFCDPVLTCCGGRKVHFLLYDPDKMEVILGRS

>CYP4B1 NM_000779
MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRRTLAKAMD
KFPGPPTHWLFGHALEIQETGSLDKVVSWAHQFPYAHPLWFGQFIGFLNIYEPDYAKA
VYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTES
TRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDL
TLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKK
IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALY
PEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVT
FVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGP
RNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLKPLGPG
SGK

>CYP4F2 NM_001082 revised exon 2 and C-terminal
MSQLSLSWLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDN
CRRLRCFPQPPRRNWFWGHQGM
IHSSEEGLLYTQSLACTFGDMGCWWVGPWQAVIHIFLPTCIKPVLF
ASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNIL
KPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKP
SEYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRR
TLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTA
SGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLH
PPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENI
KERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLAFRVLPDHTEPRR
KPELVLRAEGGLWLRVEPLS

>CYP4F2-de12b CYP4F36P NT_011295.8 EXON 12 - strand
ICMGQVFAVAEMKVVLALTLLGFRFLRHHMEPGRKPELIMHAEGGL*LLVEPLS 

>CYP4F3 NM_000896
MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDN
CCRLRCFPQPPKRNWFLGHLGL
IHSSEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLF
APAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNIL
KPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKP
SEYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDDVIQERRR
TLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTA
SGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLH
PPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNI
KERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLPDHTEPRR
KPELVLRAEGGLWLRVEPLS

>CYP4F8 NM_007253
MSLLSLSWLGLRPVAASPWLLLLVVGASWLLARILAWTYAFYHN
GRRLRCFPQPRKQNWFLGHLGLVTPTEEGLRVLTQLVATYPQGFVRWLGPITPIINLC
HPDIVRSVINTSDAITDKDIVFYKTLKPWLGDGLLLSVGDKWRHHRRLLTPAFHFNIL
KPYIKIFSKSANIMHAKWQRLAMEGSTCLDVFEHISLMTLDSLQKCIFSFDSNCQEKP
SEYITAIMELSALVVKRNNQFFRYKDFLYFLTPCGRRFHRACRLVHDFTDAVIQERRR
TLTSQGVDDFLQAKAKSKTLDFIDVLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTA
SGLSWVLYNLARHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCLKESLRLH
PPIPTFARGCTQDVVLPDSRVIPKGNVCNINIFAIHHNPSVWPDPEVYDPFRFDPENA
QKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVLALTLLRFRILPDHREPRR
TPEIVLRAEDGLWLRVEPLG

>CYP4F9P AC004609 complement(13903-33104 region)
EGMRVLTQLVATYPQGFKIWMNPITPIIRLCHPNIIWSVINASATIAPKD
EAFYKFLKPWLGDGLLVNASDKWSCHRQMLMPAFHFNMLKPYMKFFTDSV
NIMHAKWQLLASGGSAHLDMFEHTSLMTLDSVQKCVFSFDSHCQEKPSQYIATI
LELSSLFSXXXXXXXLCMDFLYYLIPSGWRFRRACCLVHDFTEAIIQEQRH
TLTSQGVDYFHEVKAKSKTLDFTDVLLLSKXXXXXXXXXXXXXXXXXXXXXX
GHNTTASGLSWVLYYLARHPEYQEHCWQEVQKLLKDHEPKEIEX
DDLAQLPFLTMYIKDSLWLHPPVPVISRCCTQDIVLPGG*VIPKGIVCLF
SNFETHHNPTVWLDPEVYDPFRFDPENSKERSPLAFIPFSAGSX
NCIGQAFAMAEMKVVLALTLLCFRVCPDHMEPRRKPEVIMYAEGGLWLWVKPLS

>CYP4F10P   human AD000685 exons 3-6 (cosmid ends in middle of exon 6) 80% to 
ATIAPKDKVFYSFLKPWLG
DGFLLSAGDKWSCHRGMLMPAFHFNILKPYMKIFDESVNIMH
AKWHLLTLEHNACLDMFEHMNLMTLDSLQKCVFSFDSQCQE
KPSEYIASVLELSSLVAKRNQQILLHMDFLYYLTHDGRHFHRACRLGHDFADAAIQEKRH
TLPSQGVDDFLQAKAKSKTLDFIDVLLISK
DEDGKELSDEDIRV*ADTFMFE
GYDTRTSGLSWVQYNLAMHPECQERCGQERQEFLKVWEPKEIEW

>CYP4F11 N-terminal is on AC011517 rest is on AC020950
MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQC
FPQPPKQNWFWGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLI
LCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHRRML
TPAFHFNLKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDS
LQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQR
FRRACHLVHDFTDAVIQERRRTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKD
EDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEV
QELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDG
RVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLAFIPFSAGP
RNCIGQAFAMAEMKVVLALTLLHFRILPTHIEPRRKPELILRAEGGLWLRVEPLGANSQ

>CYP4F12 mRNA for cytochrome P450, complete cds. AB035130
MSLLSLPWLGLRPVAMSPWLLLLLVVGSWLLARILAWTYAFYNN
CRRLQCFPQPPKRNWFWGHLGL
ITPTEEGLKDSTQMSATYSQGFTVWLGPIIPFIVLC
HPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNIL
KSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFSFDSHCQERP
SEYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRR
TLPTQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTA
SGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLH
PPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENS
KGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRA
EGGLWLRVEPLNVGLQ

>CYP4F22 AC011492 assembled gene 13 exons 114537-140651 66% to 4F3, 65% to 
MLPITDRLLHLLGLEKTAFRIYAVSTLLLFLLFFLFRLLLRFLRLCRSFYITCRRLRCFPQPPRRNWLLGHLGMVS
PNEAGLQDEKKVLDNMHHVLLVWMGPVLPLLVLVHPDYIKPLLGAS
AAIAPKDDLFYGFLKPWLG
DGLLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMH
AKWRHLAEGSAVSLDMFEHISLMTLDSLQKCVFSYNSNCQE
KMSDYISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDMVHHFTTEVIQERRR
ALRQQGAEAWLKAKQGKTLDFIDVLLLAR
DEDGKELSDEDIRAEADTFMFEG
HDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEW
DDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPK
GIICLVSIYGTHHNPTVWPDSK
VYNPYRFDPDNPQQRSPLAYVPFSAGPR
NCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVEPLPPRA*

>CYP4F23P AC011492 assembled gene 76% to 4F3, 76% to 4F8, 76% to 4F11, 73% to 
MSLLSLSWLGLGPVAASPWLLLLLVGASWLLARVLAWTYAFYDNCHRLQCFQQPPKRNCF*GHLSLVS
GNEEDMRLMEDLGHYFRDVQLWWLGSFYPVLHLVHPTFTAPVLQAS AAVALKDMSFYGFLKPWLG
DGLLISAGDKWRWHRHLLTPAFHFKILKPYVKIFNESTNIMH
AKWQRLALEGSVRLEMFEHISLMTLDSLQKCIFSFDSNCQE
KPSEYIDAILELSALSLKRHQHIFLLTDFLYFLTPNGRRFCRACDIVHNFTDAVIQERRR
TLTSQGVDDFLQAKAKSKTLDFIDVLLLAK DENGKKLSDENIRAEADTFMSG
GHDTTASGLSWVLYNLARYPEYQEHCRQEVQELLKNGDPKEIEW
DDLAQLPFLTMCLKESLRLHSPVSRIHRCCPQDGVLPDGRVIPK GNTCTISIFGIHHNPSVWPDPEV
YDPFRFDPENLQKTSPLAFIPFSAVPR
NCIGQTFAMAEMKVVLALTLLRFRVLPDHAEPRRKLELIVRAEDGLWLRVEPLSADLQ* 

>CYP4F23P_XM_065069 incorrectly assembled 4F23P
MRGNEEDMRLMEDLGHYFRDVQLWWLGSFYPVLHLVHPTFTAPV
LQASAAVALKDMSFYGFLKPWLGDGLLISAGDKWRWHRHLLTPAFHFKILKPYVKIFN
ESTNIMHAKWQRLALEGSVRLEMFEHISLMTLDSLQKCIFSFDSNCQDEYIDAILELS
ALSLKRHQHIFLLTDFLYFLTPNGRRFCRACDIVHNFTDAVIQERRRTLTSQGVDDFL
QAKAKSKTLDFIDVLLLAKDENGKKLSDENIRAEADTFMSGGHDTTASGLSWVLYNLA
RYPEYQEHCRQEVQELLKNGDPKEIEWDDLAQLPFLTMCLKESLRLHSPVSRIHRCCP
QDGVLPDGRVIPKGNTCTISIFGIHHNPSVWPDPEVLPLPPSPSRGLVYDPFRFDPEN
LQKTSPLAFIPFSAVPRRGSRRDGAGMGVLGTVRVPTPSPGNCIGQTFAMAEMKVVLA
LTLLRFRVLPDHAEPRRKLELIVRAEDGLWLRVEPLSADLQ

>CYP4F24P_AC011537 77% to 4F11
MPQLSLSWLGLGQVAAFPWLLLLLAGASRLLAGFLAWTYAFYDNCRRLQYFPQPPKQKWF 
WGQPGX 
IIATEEGLKNLTQMSATYPQGFRIWLGPIFPFIVLCHPDIVRSITNAS 
AAIAPKDDLSIRFLKPWLGEGILLSGGDK 
WSRHRRMLTPAFHFNILKPYIKIFNRSVNIMH 
DKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFSFDSHCQE 
RPSEYIATILELSALVEKRNQHILQHMDFLYYLSHDGWRFRRACRLVHDFTDAVIQERRH 
TLPTQGI 
CDFLKNKAKS*TLDFIDVLLLSK 
DEDGKVLSDEDVRAEADTFMAG
GHDTTASGLSWVLYNLARHPEYQEHCRQEVQELLKDRDPKEIEWX 
DLAQLPFLTMCVKESLRLHPPVPYTSRHRIWDIVLPDGRVIPK 
GIICIINIIGIHHNPTV*PDPEV 
YNPFRFNSENSKERSPLAFIPFSAGPR 

>CYP4F24P_XP_065068 incorrectly assembled pseudogene, deletes bad exon
MPQLSLSWLG LGQVAAFPWL LLLLAGASRL LAGFLAWTYA FYDNCRRLQY FPQPPKQKWF
WGQPGPQEGL KNLTQMSATY PQGFRIWLGP IFPFIVLCHP DIVRSITNAS AAIAPKDDLS
IRFLKPWLGE GILLSGGDKW SRHRRMLTPA FHFNILKPYI KIFNRSVNIM HDKWQHLASE
GSSRLDMFEH ISLMTLDSLQ KCIFSFDSHC QERPSEYIAT ILELSALVEK RNQHILQHMD
FLYYLSHDGW RFRRACRLTL DFIDVLLLSK DEDGKVLSDE DVRAEADTFM FAGHDTTASG
LSWVLYNLAR HPEYQEHCRQ EVQELLKDRD PKEIEWYDLA QLPFLTMCVK ESLRLHPPVP
YTSRHRIWDI VLPDGRVYNP FRFNSENSKE RSPLAFIPFS AGPSLWENVH RMGADLGAVE
DPGPGFRRDG AQMRILGAVT VPTPTRRNCI GQAFAMAKMK VVLALTLLRF RFLLDHTEPR
RKPELIMRAE GGLWLRVEPL NAGLQ

>CYP4F-se1[6:8] = 4F25P NT_078056.1|Hs9_78125 chromosome 9 
PSEYIATILELSALIV*QHQQICLCTDFLYYLTPEGRCFCRACDLVHNF 
DTIILERHCTLTSQGVDDFLNAKATFKIFDFSDAFVLSK
GYDSTASGLYWILVPLRRHP 
GVLPPRGARVLRDGNSEDIEW

>CYP4F-se2[6] old CYP4F26P AL139008 Homo sapiens chromosome 9 
SDYVATILELHALIV*WHQQICLCMDFLYYLTPEGRCFCRAYDLVHNF 
DTIILEQHCTLTSQSVDILKARATFKTLDFIDALVLSK

>CYP4F-se3[6:7:8] = 4F27P NT_005079.12|Hs2_5236 chr 2 130899265-130900232
SEHTADILELSTLIV*RRQ*ICLCLDFLYYPFLRGDASAGPVTWCTTSDTIILQQHRTLT
SQGVDDFLKAKATFKASDFIDALVLSK 
QDENGKELSDEDI*MEAGIFMSAG 
GYDSRASGLY*ILYNLTKHPDIGSAASL*CKSPNPEDIEW

>CYP4F-se4[6:7:8] CYP4F29P chr 21 AL109748 designated CYP4F3LP pseudogene
PSEYIATLFELSALIV*WHQQICLCMDFLYYPF 
PEG*CFCRACDLVHNF
DTIILEQPCTLTSQGVHDFLKTKATFKTWDFSDALVLGK 
DENGKELSDEDI*MEAGIFMST
GYDSTATGLY*ILCNLRRHPGVMPSCGARVLRDHNPEDIEW

>CYP4F-se5[6:8] 4F32P NT_022300.8|Hs2_22456 chr 2 94909781-94910782
CFLSPGSPCRNPSEYIATILELSALLV*W
HQQICLCTDFLYYLTPEGRCFCRAYDLVHNF 
DTIILEQHLTLTCRGVDDFLKAKATFKILDFSDAFLLSK 
SGYDSTASGLYWILYNLRRH
GVLPPRGARVLRDRNSEDIEW

>CYP4F-se6[6] 4F33P NT_030040.6|Hs9_30295 chromosome 9 78% TO 4F26P
SDYVATILELHALIV*WHQQICLCTDFLYYLTPEGRCFCGPATWCSTLDTIILERHCTLT 
SQGVDVLKAKATFKTLDFIDALVPSK 

>CYP4F-se7[6:7:8] = 4F34P NT_009799.12|Hs13_9956 chromosome 13 
PSEYIATLFELSALIV*WHQQICLCMDFLYYPF 296725
PIPDGDASAGPVTWCTTLDTIILEQHCTLTSQGVHDFLKAKATFKT*DFSDALMLGK
QDENGKELSDEDI*MEADIFMST 
GYDSTATGLY*ILCNLRRHPGVMPSCGARVLRDRNPEDIEW

>CYP4F-se8[6:7:8] = 4F35P NT_010859.12|Hs18_11016 chr 18
PSEYIATLFELSALIV*WHQQICLCMDFLYYPFLRGDASAGPMTWCTTLDTIILEQHCTL
TSQGVHDFLKAKATFKTWDFSDALVLGK 
QDENGKELSEEDI*MEAGIFMST 
GYESTATGLY*ILCNLRRHPGVMPSRGARVLRDRNPEDIEW

>CYP4F-se9[6:7:8] = 4F30P NT_005079.12|Hs2_5236 chr 2 131290124-131291091
CFLSLASPCRNA
SELIADILELSTLIV*RRQQICLCWDFLYYPFLRGDASAGPVTWCTTSDTIILQQHRTLT
SQGVDDFLKAKATFKASDFIDALVLSK 
QDENGKELSDEDI*MEAGIFMSAG
GYDSRASGLY*ILYNLTKHPDIGSAASL*CKSPNPEDIEW

>CYP4F-se10[6:7:8] = 4F31P NT_005058.13|Hs2_5215 chr 2 132256324-132257291
CFLSLASPCRNA
SEHIADILELSTLIV*RRQ*ICLCWDFLYYPFLRGDASAGPVTWCTTSDTIILQQHRTLT
SQGVDDFLKAKATFKASDFIDALVLSK 
QDENGKELSDEDI*MEAGIFMSAG
GYDSRASGLY*ILYNLTKHPDIGSAASL*CKSPNPEDIEW

>CYP4F-se11[6:7:8] = 4F43P NT_005058.13|Hs2_5215 chr 2 131649639-131650606
CFLSLASPCRNA
SELIADILELSTLIV*RRQQICLCWDFLYYPFLRGDASAGSVTWCTTSDTIILQQHRTLT
SQGVDDFLKAKATFKASDFIDALVLSK 
QDENGKELSDEDI*MEAGIFMSAG
GYDSRASGLY*ILYNLTKHPDIGSAASL*CKSPNPEDIEW

>CYP4F-se12[6:8] = 4F44P NT_008251.13|Hs8_8408 chromosome 8 
LWGCFLSPASPCRN
PSDYIATILELSALIM*RQQQIFLHRDFLYYVTAEGWCFCRACVVVHNF
DTIILEQHCTLTSQGVNNFLKVTATFKTLDFIDVLVLDK 
GYDSTASGLFWVL
GVLPALGAGVLRDHSPEDIEW

>CYP4F-se13[6:8] = 4F45P chr9q13 63753376-63753682 + strand build 33
LWRCFLSPTSPCRN
PSEYIATILELSALIV*QHQQICLCTDFLYYLTPEGRCFCRACDLVHNF
DTIILERHCTLTSQGVDDFLNAKATFKIFDFSDAFVLSK 
GYDSTASGLYWILVPLRRHP 
GVLPPRGARVLRDGNSEDIEW

>CYP4V2 formerly CYP4AH1 AC012525 Homo sapiens chromosome 4
MAGLWLGLVWQKLLLWGAASAVSLAGASLVLSLLQRVASYARKWQQMRPIPTVARAYPLVGHALLMKPDGR 
EFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEG 
ILTSSKQIDKSSMYKFLEPWLGLGLLT 
STGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCALDIIC 
ETAMGKNIGAQSNDDSEYVRAVYR 
MSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLQILHTFTNSV 
IAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFE 
GHDTTAAAINWSLYLLGSNPEVQKKVDHELDDV 
KSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSED
YFLTAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQG 
RHPYAYVPFSAGPRNCIG 
QKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRRNADER* 

>CYP4X1 R56515, R53456, AA652746, AC026935
MEFSWLETRWARPFYLAFVFCLALGLLQAIKLYLRRQRLLRDLRPFPAPPTHWFLGHQK
FIQDDNMEKLEEIIEKYPRAFPFWIGPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPP
LLGKGLAALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVE
VYEHINSMSLDIIMKCAFSKETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFK
LSPQGYRFQKLSRVLNQYTDTIIQERKKSLQAGVKQDNTPKRKYQDFLDIVLSAKDES
GSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSIT
WDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNP
AVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRV
TPDPTRPLTFPNHFILKPKNGMYLHLKKL

>CYP4Z1 AC026935 161971-176942 52% to 4A11 52% to 4X1 intact mRNA = AY262056
MEPSWLQELMAHPFLLLILLCMSLLLFQVIRLYQRRRWMIRALHLFPAPPAHWFYGHKE 
FYPVKEFEVYHKLMEKYPCAVPLWVGPFTMFFSVHDPDYAKILLKRQ  
DPKSAVSHKILESWV  
GRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMML 
NKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSHQGSIQLD 
STLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFT 
EKVIQDRKESLKDKLKQDTTQKRRWDFLDILLSAK 
SENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSSITW 
EHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPA 
GITVFINIWALHHNPYFWEDPQ 
VFNPLRFSRENSEKIHPYAFIPFSAGL 
RNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPPQPVRQVVLKSKNGIHVFAKKVC*

>CYP4Z2P AL731892.5 94% to 4Z1 1 stop codon in exon 8
MEPSWLQELMAHPFLLLILLCMSLLLFQVIRLYQRRRWTIRAMHLFPAPPAHWFYGHKEX 
YPVKEFEVYPELMEKYPCAVPLWVGPFTMFFNIHDPDYVKILLKRQ 
DPKSAVSHKILESWV 
GRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSKSVRMML 
NKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSHQGSIQLD 
STLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFT
EKVIQDRKESLKDKLKQDTTQKRRQDFLDILLSAKV 
ENTKDFSEADLQAEVKTFMFAGHDTTTTAISWIFYCLAKYPEHQQRC*DEIRELLGDGSSITW 
EHLSQMPYATMCIKECLRLYAPVVNISQLLDKPITFPDGRSLPA
GITVFINIWALHHNPYFWENPQ 
VFNPLRFSRESSEKMHPYAFIPFSAG 
PRNCIGQHFAIIGCKVAVALTLLCFELAPDYSRPPQPVRQMLLKSKNGIHVFAKKV 

>CYP5A1 NM_001061 this gene is 197000 bases long
MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLG
LRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLV
ENFSNFTNRMASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQAC
DLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFGTPVDSWQAPEDPFVKHCKRFF
EFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERR
RDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVG
QAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLP
YLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPE
TFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPE
TQVPLQLESKSALGPKNGVYIKIVSR

>CYP7A1 NM_000780
MMTTSLIWGIAIAACCCLWLILGIRRRQTGEPPLENGLIPYLGC
ALQFGANPLEFLRANQRKHGHVFTCKLMGKYVHFITNPLSYHKVLCHGKYFDWKKFHF
ATSAKAFGHRSIDPMDGNTTENINDTFIKTLQGHALNSLTESMMENLQRIMRPPVSSN
SKTAAWVTEGMYSFCYRVMFEAGYLTIFGRDLTRRDTQKAHILNNLDNFKQFDKVFPA
LVAGLPIHMFRTAHNAREKLAESLRHENLQKRESISELISLRMFLNDTLSTFDDLEKA
KTHLVVLWASQANTIPATFWSLFQMIRNPEAMKAATEEVKRTLENAGQKVSLEGNPIC
LSQAELNDLPVLNSIIKESLRLSSASLNIRTAKEDFTLHLEDGSYNIRKDSIIALYPQ
LMHLDPEIYPDPLTFKYDRYLDENGKTKTTFYCNGLKLKYYYMPFGSGATICPGRLFA
IHEIKQFLILMLSYFELELIEGQAKCPPLDQSRAGLGILPPLNDIEFKYKFKHL

>CYP7B1 NM_004820
MAGEVSAATGRFSLERLGLPGLALAAALLLLALCLLVRRTRRPG
EPPLIKGWLPYLGVVLNLRKDPLRFMKTLQKQHGDTFTVLLGGKYITFILDPFQYQLV
IKNHKQLSFRVFSNKLLEKAFSISQLQKNHDMNDELHLCYQFLQGKSLDILLESMMQN
LKQVFEPQLLKTTSWDTAELYPFCSSIIFEITFTTIYGKVIVCDNNKFISELRDDFLK
FDDKFAYLVSNIPIELLGNVKSIREKIIKCFSSEKLAKMQGWSEVFQSRQDVLEKYYV
HEDLEIGAHHLGFLWASVANTIPTMFWAMYYLLRHPEAMAAVRDEIDRLLQSTGQKKG
SGFPIHLTREQLDSLICLESSIFEALRLSSYSTTIRFVEEDLTLSSETGDYCVRKGDL
VAIFPPVLHGDPEIFEAPEEFRYDRFIEDGKKKTTFFKRGKKLKCYLMPFGTGTSKCP
GRFFALMEIKQLLVILLTYFDLEIIDDKPIGLNYSRLLFGIQYPDSDVLFRYKVKS

>CYP8A1 D83402
MAWAALLGLLVALLLLLLLSRRRTRRPGEPPLDLGSIPWLGYAL
DFGKDAASFLTRMKEKHGDIFTILVGGRYVTVLLDPHSYDAVVWEPRTRLDFHAYAIF
LMERIFDVQLPHYSPSDEKARMKLTLLHRELQALTEAMYTNLHAVLLGDATEAGSGWH
EMGLLDFSYSFLLRAGYLTLYGIEALPRTHESQAQDRVHSADVFHTFRQLDRLLPKLA
RGSLSVGDKDHMCSVKSRLWKLLSPARLARRAHRSKWLESYLLHLEEMGVSEEMQARA
LVLQLWATQGNMGPAAFWLLLFLLKNPEALAAVRGELESILWQAEQPVSQTTTLPQKV
LDSTPVLDSVLSESLRLTAAPFITREVVVDLAMPMADGREFNLRRGDRLLLFPFLSPQ
RDPEIYTDPEVFKYNRFLNPDGSEKKDFYKDGKRLKNYNMPWGAGHNHCLGRSYAVNS
IKQFVFLVLVHLDLELINADVEIPEFDLSRYGFGLMQPEHDVPVRYRIRP

>CYP8B1 AF090318 AC010192
MVLWGPVLGALLVVIAGYLCLPGMLRQRRPWEPPLDKGT
VPWLGHAMAFRKNMFEFLKRMRTKHGDVFTVQLGGQYFTFVMDP
LSFGPILKDTQRKLDFGQYAKKLVLKVFGYRSVQGDHEMIHSASTKHLRGDGLKDLNE
TMLDSLSFVMLTSKGWSLDASCWHEDSLFRFCYYILFTAGYLSLFGYTKDKEQDLLQA
GELFMEFRKFDLLFPRFVYSLLWPREWLEVGRLQHLFHKMLSVSHSQEKEGISNWLGN
MLQFLREQGVPSAMQDKFNFMMLWASQGNTGPTSFWALLYLLKHPEAIRAVREEATQV
LGEARLETKQSFAFKLGALQHTPVLDSVVEETLRLRAAPTLLRLVHEDYTLKMSSGQE
YLFRHGDILALFPYLSVHMDPDIHPEPTVFKYDRFLNPNGSRKVDFFKTGKKIHHYTM
PWGSGVSICPGRFFALSEVKLFILLMVTHFDLELVDPDTPLPHVDPQRWGFGTMQPSH
DVRFRYRLHPTE

>CYP11A1 NM_000781
MLAKGLPPRSVLVKGYQTFLSAPREGLGRLRVPTGEGAGISTRS
PRPFNEIPSPGDNGWLNLYHFWRETGTHKVHLHHVQNFQKYGPIYREKLGNVESVYVI
DPEDVALLFKSEGPNPERFLIPPWVAYHQYYQRPIGVLLKKSAAWKKDRVALNQEVMA
PEATKNFLPLLDAVSRDFVSVLHRRIKKAGSGNYSGDISDDLFRFAFESITNVIFGER
QGMLEEVVNPEAQRFIDAIYQMFHTSVPMLNLPPDLFRLFRTKTWKDHVAAWDVIFSK
ADIYTQNFYWELRQKGSVHHDYRGMLYRLLGDSKMSFEDIKANVTEMLAGGVDTTSMT
LQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKASIKETLRLHPISV
TLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTRWLSKDKNITYF
RNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRVEIQHLSDVGTTFNLILMPEKPIS
FTFWPFNQEATQQ

>CYP11B1 NM_000497
MALRAKAEVCMAVPWLSLQRAQALGTRAARVPRTVLPFEAMPRR
PGNRWLRLLQIWREQGYEDLHLEVHQTFQELGPIFRYDLGGAGMVCVMLPEDVEKLQQ
VDSLHPHRMSLEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPEVLSPNAVQRFLPM
VDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSS
ASLNFLHALEVMFKSTVQLMFMPRSLSRWTSPKVWKEHFEAWDCIFQYGDNCIQKIYQ
ELAFSRPQQYTSIVAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNP
NVQQALRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVL
QNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGSGRNFYHVPFGFGMRQC
LGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSFILRPSMCPLLTFRAIN

>CYP11B2 NM_000498
MALRAKAEVCVAAPWLSLQRARALGTRAARAPRTVLPFEAMPQH
PGNRWLRLLQIWREQGYEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQ
VDSLHPCRMILEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPM
VDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSS
ASLNFLHALEVMFKSTVQLMFMPRSLSRWISPKVWKEHFEAWDCIFQYGDNCIQKIYQ
ELAFNRPQHYTGIVAELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNP
DVQQILRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVL
QNYHIPAGTLVQVFLYSLGRNAALFPRPERYNPQRWLDIRGSGRNFHHVPFGFGMRQC
LGRRLAEAEMLLLLHHVLKHFLVETLTQEDIKMVYSFILRPGTSPLLTFRAIN

>CYP17A1 NM_000102
MWELVALLLLTLAYLFWPKRRCPGAKYPKSLLSLPLVGSLPFLP
RHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQMATL
DIASNNRKGIAFADSGAHWQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATH
NGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSLVDLV
PWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDSITNMLDTLMQAKMNSDNG
NAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQ
NVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEV
IINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQ
ELFLIMAWLLQRFDLEVPDDGQLPSLEGIPKVVFLIDSFKVKIKVRQAWREAQAEGST

>CYP19A1 NM_000103
MVLEMLNPIHYNITSIVPEAMPAATMPVLLLTGLFLLVWNYEGT
SSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSS
MFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRM
VTVCAESLKTHLDRLEEVTNESGYVDVLTLLRRVMLDTSNTLFLRIPLDESAIVVKIQ
GYFDAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRCRISTEEKLEECM
DFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIK
EIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGT
NIILNIGRMHRLEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAI
LVTLLRRFHVKTLQGQCVESIQKIHDLSLHPDETKNMLEMIFTPRNSDRCLEH

>CYP20A1 AC011737.8 chr 2 (missing exons 12,13) AC080075.2 (missing exons 1,7,8)
MLDFAIFAVTFLLALVGAVLYLYP 
ASRQAAGIPGITPTEEK 
DGNLPDIVNSGSLHEFLVNLHERYGPVVSFWFGRRLVVSLGTVDVLKQHINPNKTS 
DPFETMLKSLLRYQSGGGSVSENHMRKKLYENGVTDSLKSNFALLLK 
LSEELLDKWLSYPETQHVPLSQHMLGFAMKSVTQMVMGSTFEDDQEVIRFQKNHGT 
VWSEIGKGFLDGSLDKNMTRKKQYED 
ALMQLESVLRNIIKERKGRNFSQHIFIDSLVQGNLNDQQ 
ILEDSMIFSLASCIITAK 
LCTWAICFLTTSEEVQKKLYEEINQVFGNGPVTPEKIEQLR 
YCQHVLCETVRTAKLTPVSAQLQDIEGKIDRFIIPRE 
TLVLYALGVVLQDPNTWPSPHK 
FDPDRFDDELVMKTFSSLGFSGTQECPELR 
FAYMVTTVLLSVLVKRLHLLSVEGQVIETKYELVTSSREEAWITVSKRY

>CYP21A2 M26856
MLLLGLLLLLPLLAGARLLWNWWKLRSLHLPPLAPGFLHLLQPD
LPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVS
RNYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVA
IEEEFSLLTCSIICYLTFGDKIKDDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRF
FPNPGLRRLKQAIEKRDHIVEMQLRQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQ
LLEGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSR
VPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA
HLDETVWERPHEFWPDRFLEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAF
TLLPSGDALPSLQPLPHCSVILKMQPFQVRLQPRGMGAHSPGQNQ

>CYP21A1P 97% to 21A2 NT_033167.1|Hs6_33343
MLLLGLLLLLPLLAGARLLWNWWKLRSLHLLPLAPGFLHLLQPDLPIYLLGLTQKFGPIYRLHLGLQ 
DVVVLNSKRTIEEAMVKKWADFAGRPEPLTCK 
LVSKNYPDLSL
XXWSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCE 
RMRAQPGTPVAIEEEFSLLTCSINCYLTFGDKIK 
EDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLR 
FFPNPGLRRLKQAIEKRDHNEEKQLRQHK
ESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHLHMAAVDLLIGGTETTANTLSWAVV
FLLHHPE 
IQQRL*EELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLWPVV
PLALPHRTTRPS 
SISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWP 
DRFLEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALPSLQPLPH
CSVILKMQPFQVRLQPRGMGAHSPGQNQ 

>CYP24A1 NM_000782
MSSPISKSRSLAAFLQQLRSPRQPPRLVTSTAYTSPQPREVPVC
PLTAGGETQNAAALPGPTSWPLLASLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLG
SFESVHLGSPCLLEALYRTESVPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSA
FQKKLMKPGEVMKLDNKINEVLADFMGRIDELCDERGHVEDLYSELNKWSFESICLVL
YEKRFGLLQKNAGDEAVNFIMAIKTMMSTFGRMMVTPVELHKSLNTKVWQGHTLAWDT
IFKSVKACIDNRLEKYSQQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTANSL
MWILYNLSRNPQVQQKLLKEIQSVLPENQRPREEDLRNMPYLKACLKESMRLTPGVPF
TTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWLQEKEKINPFA
HLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPVEMLHSGTLVPSRELPI
AFCQR

>CYP26A1 NM_000783 
MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPL
PPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILL
GDDRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEV
GSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMT
RNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIE
HSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKG
LLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGW
NVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKI
LLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI

>CYP26B1 AC007002
MLFEGLDLVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMGFPLIGETGHWLLQ
GSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRMLLGPNTVSNS
IGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSHPEAINVYQEAQ
KLTFRMAIRVLLGFSIPEEDLGHLFEVYQQFVDNVFSLPVDLPFSGYRR
GIQARQILQKGLEKAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIF
AAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLD
CVIKEVMRLFTPISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDP
DRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRI
TLVPVLHPVDGLSVKFFGLDSNQNEILPETEAMLSATV

>CYP26C1 AL358613.11 May 2, 2001 522 amino acids, 6 exons, 
MFPWGLSCLSVLGAAGTALLCAGLLLSLAQHLWTLRWMLSRDRASTLPLPKGSMGWPFFGETLHWLVQ 
GSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRRRRK 
VLARVFSRAALERYVPRLQGALRHEVRSWCAAGGPVSVYDASKALTFRMAARILLGLRL
DEAQCATLARTFEQLVENLFSLPLDVPFSGLRK 
GIRARDQLHRHLEGAISEKLHEDKAAEPGDALDLIIHSARELGHEPSMQELK 
ESAVELLFAAFFTTASASTSLVLLLLQHPAAIAKIREELVAQGLGRACGCAPGAAGGSEGPPPD
CGCEPDLSLAALGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELD 
GYQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGAAREDSRGASSRLHYIPFGGGARSCLG
QELAQAVLQLLAVELVRTARWELATPAFPAMQTVPIVHPVDGLRLFFHPLTPSVAGNGLCL*

>CYP27A1 NM_000784
MAALGCARLRWALRGAGRGLCPHGARAKAAIPAALPSDKATGAP
GAGPGVRRRQRSLEEIPRLGQLRFFFQLFVQGYALQLHQLQVLYKAKYGPMWMSYLGP
QMHVNLASAPLLEQVMRQEGKYPVRNDMELWKEHRDQHDLTYGPFTTEGHHWYQLRQA
LNQRLLKPAEAALYTDAFNEVIDDFMTRLDQLRAESASGNQVSDMAQLFYYFALEAIC
YILFEKRIGCLQRSIPEDTVTFVRSIGLMFQNSLYATFLPKWTRPVLPFWKRYLDGWN
AIFSFGKKLIDEKLEDMEAQLQAAGPDGIQVSGYLHFLLASGQLSPREAMGSLPELLM
AGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVLKE
TLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWL
RNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPETGEL
KSVARIVLVPNKKVGLQFLQRQC

>CYP27B1 NM_000785
MTQTLKYASRVFHRVRWAPELGASLGYREYHSARRSLADIPGPS
TPSFLAELFCKGGLSRLHELQVQGAAHFGPVWLASFGTVRTVYVAAPALVEELLRQEG
PRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNN
VVCDLVRRLRRQRGRGTGPPALVRDVAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPDT
ETFIRAVGSVFVSTLLTMAMPHWLRHLVPGPWGRLCRDWDQMFAFAQRHVE RREAEAA
MRNGGQPEKDLESGAHLTHFLFREELPAQSILGNVTELLLAGVD TVSNTLSWALYELS
RHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPD
KDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPARWLGEGPTPHPFASLPFGF
GKRSCMGRRLAELELQMALAQ 
ILTHFEVQPEPGAAPVRPKTRTVLVPERSINLQFLDR

>CYP27C1 AC027142 43% identical to 27A1 assembled gene
MQTSAMALLARILRAGLRPAPERGGLLGGGAPRRPQPAGARLPAGARAEDKGAGRPGSPPG 
GGRAEGPRSLAAMPGPRTLANLAEFFCRDGFSRIHEIQ 
QKHTREYGKIFKSHFGPQFVVSIADRDMVAQVLRAEGAAPQRANMESWREYRDLRGRATGLISA 
EGEQWLKMRSVLRQRILKPKDVAIYSGEVNQVIADLIKRIYLLRSQAEDGETVTNVNDLFFKYSME 
GVATILYESRLGCLENSIPQLTVEYIEALELMFSMFKTSMYAGAIPRWLRPFIPKPWREFC 
RSWDGLFKFS 
QIHVDNKLRDIQYQMDRGRRVSGGLLTYLFLSQALTLQEIYANVTEMLLAGVDT 
TSFTLSWTVYLLARHPEVQQTVYREIVKNLGERHVPTAADVPKVPLVRALLKETLR 
LFPVLPGNGRVTQEDLVIGGYLIPKG 
TQLALCHYATSYQDENFPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQ 
LLQHFEIKTSSQTNAVHAKTHGLLTPGGPIHVRFVNRK*

>CYP39A1 AC008104 AL035670 note heme region exon corrected 1/18/02
MELISPTVIIILGCLALFLLLQRKNLRRPPCIKGWIPWIGVGFEFGKAPLEFIEKARIK
YGPIFTVFAMGNRMTFVTEEEGINVFLKSKKVDFELAVQNIVYRT
ASIPKNVFLALHEKLYIMLKGKMGTVNLHQFTGQLTEELHEQLENLGTHGTMDLNNLVR
HLLYPVTVNMLFNKSLFSTNKKKIKEFHQYFQVYDEDFEYGSQLPECLLR 
NWSKSKKWFLELFEKNIPDIKACKSAKDNSM 
TLLQATLDIVETETSKENSPNYGLLLLWASLSNAVP
VAFWTLAYVLSHPDIHKAIMEGISSVFGKAG
KDKIKVSEDDLENLLLIKWCVLETIRLKAPGVITRKVVKPVEIL
NYIIPSGDLLMLSPFWLHRNPKYFPEPELFKPERW
KKANLEKHSFLDCFMAFGSGKFQCPARW
FALLEVQMCIILILYKYDCSLLDPLPKQ
SYLHLVGVPQPEGQCRIEYKQRI

>CYP46A1 NM_006668
MSPGLLLLGSAVLLAFGLCCTFVHRARSRYEHIPGPPRPS 
FLLGHLPCFWKKDEVGGRVLQDVFLDW 
AKKYGPVVRVNVFHKTSVIVTSPESVK 
KFLMSTKYNKDSKMYRALQTVFGER 
LFGQGLVSECNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAK 
AAFGMETSMLLGAQKPLSQAVKLMLEGITASRNTLAK 
FLPGKRKQLREVRESIRFLRQVGRDWVQRRREALKRGEEVPADILTQILK 
AEEGAQDDEGLLDNFVTFFIA 
GHETSANHLAFTVMELSRQPEIVAR 
LQAEVDEVIGSKRYLDFEDLGRLQYLSQ 
VLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLL 
FSTYVMGRMDTYFEDPLTFNPDRFGPGAPK 
PRFTYFPFSLGHRSCIGQQFAQ 
MEVKVVMAKLLQRLEFRLVPGQRFGLQEQATLKPLDPVLCTLRPRGWQPAPPPPPC

>CYP46A-se1[12:13:14] = old 46A4P NT_004424.11|Hs1_4581 chr 1 
DPLTFNPYRFGPGAPKPRFTYFPFSLGHHSCIGQQFAQMEVKVVMAKLLQRLEFQLVPGP 
RFGLQ*QATLKPLDPELCTLRPRGWQPAAPPPRC

>CYP51A NM_000786
MAAAAGMLLLGLLQAGGSVLGQAMEKVTGGNLLSMLLIACAFTL
SLVYLIRLAAGHLVQLPAGVKSPPYIFSPIPFLGHAIAFGKSPIEFLENAYEKYGPVF
SFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEDVYSRLTTPVFGKGVAYDVPNPVFLE
QKKMLKSGLNIAHFKQHVSIIEKETKEYFESWGESGEKNVFEALSELIILTASHCLHG
KEIRSQLNEKVAQLYADLDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKDIFYKAIQK
RRQSQEKIDDILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLA
RDKTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMART
PQTVAGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGA
GRHRCIGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTMIHTPENPVIRYKRRS
K

>CYP51P1 processed pseudogene U36926 5 in frame stops
MAAAAGMMLLGLLQAGG*VLGQAMEEVAGGNLLSMLLIACAFTLSLVYLFRLAAGHLVQL
TAGAKSPPYIFSPVPFLGHAIAFGKSPTEFLENAYGNYGPVFSFIMVGKAFTYLLGSDAA
ALLFNSKNEVLNAEDVYSRLTTPVFG*GVAYDVPNPVFLEQKKTLKSGLNIAHFK*HVSI
IEKETKEYFESWGESGEKNVFAALSELIILTASHYLHGKEIRSQHNEKVAQLYADLDGGF
SHAAWLLPGWLPLPCFRRRDRAHQEIKDIFYKAIQKRRQSQEKIDDILQTLLDATYKDGR
PLTDDEVAGMLTGLLLAEQHTSSTSA*MGFFLARDKTLQEKCYLEQKTVCGENLPPLTY 
DQLKDLNLLDRCIKETLRLRHPVMIMMRMARIPKTVAGYTIPPGHQVCVSPTVNQRLKDS
WVEHLDFNPDRYL*DNPASREKFAYVPFGAGHHGCTGENFAYVQIKTIWSTMLRLYEFDL
IDGYFPTVNYTTMIHTPENPVIHYK*RSK 

>CYP51P2 processed pseudogene U40053 
MAAAAGMMLLGLLQAG
GSVLGQAMEEVTGGNLLSMLLIACTFTLSLVYLFRLAAGHLVQLPAGAKSPPYVFSPVP 
FPGHAIAFGKSPVEFLE 
NAYEKYGPVFSFTMVGKTFTYL 
LGSDAAALLFNSKNEDQNAEDVYSHLTTPVFGKGVAYDVPNPVFLEQKKMLKSGLNKAHF
KQHVSL 
EKETKEYFQSWGESGEKNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFS
HAAWLLPGWLPLPSFRCRDRAHWEIKDIFYKAIQKRRQSQEKIDDILQTLLDATYKDGRP
LTDDEVAGMLIGLLLAGQHSSSTTSAWMDFFLARDKTLQEKCYLEQKTVCGENLPPLTYD
QLKGLNLLDRCIKETLRLRPPIMIMMRMARTPQTVVGYTIPPGHQVCVSPTVNQRPKDSW
VERLDFNPDCYLQDNPASGEKFAYVPFGAGCHR*IGENFAYVQIKTIWSTMLRLYEFDLI
DGYFPIVNYTTMIHTPENPLIHYKRRSK 

>CYP51P3 NT_025741.8|Hs6_25897 chromosome 6 CYP51P3
MLGLVQMSRSALGQLVEWVAGESDSLLSMLLISCAFILSLVCFATIVTTWPSCQLVQNAH 
HMFSLPLHSLGMPYIWEKLN*ISRKCI*EVWAYEKYGPVCSFSVVSKTFT 
ICFLSHYIPWACHTFGKS*IEFLESAYEKYGHMRSMDLYVVFLW*ARHLLLERDETAL 
LFNSKTKDAEDVYSHLRTPAFGKGVECDMPNPAFLGQEKMLKSSLKVAHFRQQVSI 
TEKERNTFKLGRKQRKKLCEALSELII 
FDS*PWFTWKGNQKSTQ*EVAQLCADVSGGFKPLA 
WLRPRWLPLRGCRSSYKAH*EHNYCL*GNPETQKPEEKIQGILQTLLDTTDKGEHLLAD 
EEVTGLLIRLFSGQHTSSTTGA*MSCFVARDETLHEKCYLKQKTVRGEDLPSLTYDLLK 
VIGRTIPAGHQMGLSLTVNQGFQDTWVELVDPDQ*LQDISTGEK 
GGGRHHIGKNFAHVQIKTVWSTLFHLYEFDFIDGYFPTVNYKTVVHHTPKNPVITYK*R