>CYP1A NM_131879 AF210727 AY398333 AB078927 AF057713
MALTILPILGPISVSESLVAIITICLVYLLMRLNRTKIPDGLQK
LPGPKPLPIIGNVLEIGNNPHLSLTAMSKCYGPVFQIQIGMRPVVVLSGNDVIRQALL
KQGEEFSGRPELYSTKFISDGKSLAFSTDQVGVWRARRKLALNALRTFSTVQGKSPKY
SCALEEHISNEGLYLVQRLHSVMKADGSFDPFRHIVVSVANVICGICFGRRHSHDDDE
LVRLVNMSDEFGKIVGSGNPADFIPFLRILPSTTMKKFLDINERFSKFMKRLVMEHYD
TFDKDNIRDITDSLINHCEDRKLDENSNLQVSDEKIVGIVNDLFGAGFDTISTALSWA
VVYLVHYPEVQERLQRELDEKIGKDRTPLLSDRANLPLLESFILEIFRHSSFLPFTIP
HCTSKDTSLNGYFIPKDTCVFVNQWQVNHDPELWKDPSSFIPDRFLTADGTELNKLEG
EKVLVFGLGKRRCIGESIGRAEVFLFLAILLQRLKFTGMPGEMLDMTPEYGLTMKHKR
CLLRVTPQPGF

>NA7989 CYP1A sequence but this does not match cDNA (poor seq?)
7823 TLKDTSLHGYFIPQDTRRFVNPGAVHPDP 7737

>CYP1B AJ249074
494367 MMDVLLALRDLLQLSTRSVLLSLMVCLMLMFRRRQLVPGPFSWPVIGNAAQLGNTP 494534
494535 HFYLSRMAQKYGDVFQIKLGSRNVVVLNGDAIKEALVKKATDFAGRPDFASFRFVSNGKS 494714
494715 MAFGNYTPWWKLHRKVAQSTVRNFSTANIQTKQTFEKHIVSEIGELIRLFLNKSREQQFF 494894
494895 QPHRYLVVSVANTMSAVCFGNRYAYDDAEFQQVVGRNDQFTKTVGAGSMVDVMPWMQYFP 495074
495075 NPIRTLFDQFKELNKEFCAFIELKVSEHRKTISPSHVRDMTDAFIVALDKGLSGGSGVSL 495254
495255 DKEFVPPTISDIF 495293
495379 GASQDTLSTALQWIILLLVR  495438
497442 YPEIQKRLQEDVDRVVDRSRLPTIADQPHLPYLMAFIYEVMRFTSFTPLTIPHS 497603
497604 TTKDTSINGYPIPKDTVIFVNQWSLNHDPTKWDQPEVFNPQRFLDEDGSLNKDLTTNVLI 497783
497784 FSLGKRRCIGEDVSKIQLFLFTSVLVHQCSFKAESTPNMDYEYGLTLKPKPFKVSVTARD 497963
497964 SSDLLDSLVGTSQTPTEKR 498020

>CYP1C1 NA17619 79% to CYP1C2 zfishC-a2047d05.q1c Z35723-a191c08.p1c zfishC-a1626a06.q1c
     MEAEFGLKSSSIMREWSGQ
1329 VQPALIASFIILFFLEACLWVRNLTFKKRLPGPFAWPLVGNAMQLGQMPHITFSKLAKKY 1508
1509 GNVYQIRLGCSDIVVLNGDAAIRKALVQHSTEFAGRPNFVSFQMISGGRSLTFTNYSKQW 1688
1689 KTHRKVAQSTLRAFSMANSQTRKTFEQHVVGRRQWDLVQKFLRLSADGRHFNPAHEATVA 1868
1869 AANVICALCFGKRYGHDDPEFRTLLGRENKFGETVGVESLVDVMLWLQS 2015
2017 FPNPVRSVYQNFXTINKEFFNYVKDKVLQHRDTYDRDVTRDMSDAIIGVIEHGKESTLT 2193
2194 KDFVESTVTDLIGAGQDTVSTAMQWMLLLLVKYPSIQSKLQEQIDKVVGRDRLPSIED 2367
2368 RCNLAYLDAF 2394 
2397 IYETMRFTSFVPVTIPHSTTSDVTIEGLHIPKDTVVFINQWSVNHDPQKWSDPHIFNPSR 2576
2577 FLDENGALNKDLTSSVMIFSTGKRRCIGEQIAKVEVFLFSAILLHQCKFERDPSQDLSMD 2756
2757 CSYGLALKPLHYTISAKLRGKLFGLVSPA 2843

>CYP1C2 NA4026
     MAQSDSEFSILKEWSGQIQPALIASFIILCCLEACFWVRNITLKKKRL
1114 PGPFAWPLVGNAMQLGQMPHITFSKLAKKYGNVYQIRLGSSDIVVLNGESAIRSALLQHS 1293
1294 TEFAGRPNFVSFQYVSGGTSMTFASYSKQWKMHRKIAQSTIRAFSSANSQTKKSFEKHIV 1473
1474 AEAVDLVETFLKIQHFNPSHELTVAAANIICALCFGKRYGHDDLEFRTLLGNVNKF 1641
1642 SETVGAGSLVDVMPWLQTFPNPIRSIFQSFKDLNSDFFSFVKGKVVEHRLSYDPEVIRDM 1821
1822 SDAFIGVMDHADEETGLTEAHTEGTVSDLIGAGLDTVSTALNWMLLLLVKYPSIQSKL 1995
1996 QEQIDKVVGRDRLPSIEDRCNLAYLDAFIYETMRFTSFVPVTIPHSTTSDVTIEGLHIPK 2175
2176 DTVVFINQWSVNHDPQKWSDPHIFNPSRFLDENGALDKDLTNSVMIFSIGRRRCIGDQIA 2355
2356 KVEVFLISAILIHQLTFESDPSQDLTLNCSYGLTLKPFDYKISAKPRGSIVN* 2514

>zK229D2 CYP1D?
89156 ILCAFALLLLALHGRRRAPGVPVPPGPRPWPIVGNFLQMEEQVHLSLTNLRVQYGDVFQ 89332
89333 VKMGSLVVVVLSGYTTIKEALVRQGDAFAGRPDLYTFSAVANGTSMTFSEKYGEAWVLHK 89512
89513 KICKNALRTFSQTEPKDSNASCLLEERICVEAIDMVETLKAQGEEFGDSGIDPVQLLVTS 89692
89693 VANVVCTLCFGKRYSHNDKEFLTIVHINNEVLRLFAAGNLADFFPIFRYLPSPSLRK 89863
89864 MVEFINRMNNFMERNIMEHLVNFD 89935

95618 GFDTIITGLQWSLLYLIKFPNIQDKIVQEI 95707
98379 LDNQVGMDRLPQFKDRPNMPYTEAFINEVFRHASYMPFTIPH
      SSTTENITLNGYFIPKDTCVFINQYQVNHD 98696
101361 WDDPESFRPERFLTLSGHLNKSLTEKVMIFGMGIRRCLGDNIARLEMFVFLTTLLHRLHI 101540
101541 ENVPGQELDLSSTFGLTMKPRPYRIKIIPR 101630

>CYP2K6.a AF283813 Zv3 CYP2K6.a ctg12742 CONTINUES ON zC8C17
6027 MALIEAFLLQGSPTGTILGALLLFLVIYLFSSSSSSQDKEKYPPGPKPLPLLGNLHILDLKKTYLSLLE 5821
1390 LSKKYGPIYTVYLGPKKVVILSGYKIVKEALVNLSEEFGDRDISPIFHDFNRGY 1229
1149 GIAFSNGENWREMRRFALSTLRDFGMGRKRSEELIIEEIKYVKEEFEKFX 1003
 917 GNPFETKLPLALAISNIIASIVFSVRFEYSNTKLHRMVGRAYENMKLTGSPSVQ 756
CONTINUES ON zC8C17
113329 IYNMFPWLRPIVANRNQIVKNLRDTFKQNEELINGVMKTLDPFNPRGIVDSFLIRQQKDE 113150
       ESGKTDSLYNSNNLYCTVNNLFGAGTDTTVTTLRWGLLLMAKYPEIQ 112907
112636 AKVQDEIERVIGGRQPVVEDRKNLPYTDAVIHEIQRFADISPIGAPRQTTCDVHLNGYFIKK 112451
111834 GTPVFPLLVSVLRDENEWETPDSFNPKHFLNKQGQFVKKDAFMPFGA 111694
111610 GRRVCIGESLARMELFLFFTSLLQYFRFTPPPGVSEDDLDLTPVVGFTLNPKPHQLCAVKRS 111425

>CYP2K7 AF487990 zfishG-a1000a05.p1c ctg11670 (EXONs 2,3 only)
BF157099 = fl60g01.y1 CD758767 CK238099 AI722087 = fd19b07.y1
MALVGALLPGLSFTVGMVVAFLLLFLVISYFSSSKDQGKYPPGPKPLPLLGNLHILDLKNTYMSLWK
31221 LSKQYGPVYTVHMGPRTVVVLSGYKAVKEALVNLSEEFGERDISPIFQDFNEGY 31060
30979 GIVFSNGENWKEMRRFALSNLRDFGMGKKRSEELITEEIKYLKEEIERFR 30830
GKPFETKLPLAMAISNVIALIVYSIRFEYNSPKFHRAIVRANENAKLVGSPSVQ
LYNMFPWLRLFVINQKRVVDNVQESFKQIGEIVNGLKKTLNPQSPRGIADKFLIQQQK
DKESGKTDSLYNSNNFLTTINNLFGAGIDTTVTTLRWGLLLIAKYPEIQ
AKVHDEIDSVIGERQPVPDDRKNLPYTDAVIHEIQRFADILPIGLLRQTSCDVHLNGYLIKK
GTSVFPLIASVLRDENEWETPDSFNPKHFLNKQGQFVKKDAFMPFGA
GRRLCIGESLARMELFLFFTSLLQHFCFTPPPGVSEDELDLTPVVGFTLSPMPHKLCAVKRF

>CYP2K8.b 63% TO 2K6 ctg12742 Zv3 05/2004 zfishC-a34h06.q1c, zfishG-a144a09.p1c
zfishK-a820d04.p1c, zfishB-a687d05.p1c, zfishC-a18b11.q1c
37883 MAVMETLLMPVSITGVLLSAVLLFLVVYLISISSSSPEDPPGPKPLPLLGNLHTLDLKNLHVSLWE 37686
35629 LSKKYGPVFKVHLGRKKVVVLAGYKTVKQALVNQAEEFGERDITPIFQDCNQG 35471
33457 GIVFANGERWRTMRRFALSTLRDFGMGKKLSEEKIVDETRYLREVFMKF 33311
33221 GQPFDTTQPVNYAVSNIISAIVYGKRFEYEDPAFQDMVNKANMNIRMIGSAVIQ 33060
29862 IYNMCPFLGPWIKTWRQLMKNMESTRRQIQTLADVLQETLNPLDCRGLIDSFLIRKQ 29692
27450 XQETGEKDSSFNDQNLLITVSNLFAAGTDTTGTTLRWGLMLMAKYPQIQ 27307
27166 XRVQEEIDQVLGGREPVAEDRKNLPYTDAVIHETQRLANILPLNLPHKTSCDVTFNGYFIKK 26984 (0)
23794 GTCVLPLLTSVLRDETEWETPDTFNPQHFLDEKGQLIKRDAFMPFSA 23654 (1)
20596 GRRACLGESLARMELFLFFTSLLQYFRFSPPPGASEDELDLTPVVGLTLNPSPHKLCAVIR 20414

>CYP2K16.c ctg12742 68% to 2K8
57491 MAFLDALLHVSSTGTLICFLLLLLVAYLLFLRSQSDENEPPGPKPLPLLGNLLMLDVNKPHLSLCE 57294
52779 MAKQFGPVFKVYFGPKKVVVLAGYKAVKQALVNYAEAFGDREIMPLFHDFTKGH 52618
52022 GIIFANGESWREMRRFALTNLRDFGMGKKKIEEKIIEETCHLREEFEKFX 51876
50840 GKPFETAQLMNYAASSVISSIVYGRRFEYTDPQLRTMVDRANESVRLSGSASVQ 50679
50581 LYNMFPFLGPLLKNWRQLMKNLHLDIEEISELVNGLHQTLNHQDLRGFVDSFLVRKQX 50411
50317 DQDSGEKDSHFHEQNLIYTVGNLFVAGTDTTSTTLRWSLLLMAKYPHIQ 50171
43796 XRVQEEIDQVIGGRQPVSEDRKNLPYTDAVIHETQRLANIVPMSIPHMTSSDITFNGYFIKK 43614
43440 GTCIFPLLTSVLWDEDEWETPHIFNPNHFLDEQGRFVKRDAFMPFSA 43300
42178 GRRICLGESLARMELFLFFTSLLQYFRFTPPPGVSEDELELTPAVGFTLNPIAHKLCAVKR 41996

>CYP2K17.d ctg12742 BI427723 zfishC-a1846d04.p1c zfishC-a1146b02.p1c
66780 MAVVESLLHFSSAGTLLGTLLLLLVFYRLSRDSEFQKKRKDPPGPKPIPLLGNLLTLDLSRPFDSLCE 66577
63586 LSKTYGNVYQVFLGPKKVVVLIGHKTVKEALVNYADEFGERDITPIFRXXXXXX 63443
63238 GILFSNGESWKEMRRFAISNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFX 63092
62992 GKPFDTTQPVNYAVSNIISSIVYGSRFEYTDPRFTEMVDRANENIRVSGSVSMX 62834
62747 LYNIFPWLGLFLNSKRTVVRNMLKNRAEFMKLITGLQETLNIHDRRGFVDSFLIRKQX 62577
60380 XXXXGKKDSYFHAENLLMTVGNLFAAGTDTTGTTLRWGLMLMAKYPQIQ 60246
60158 XRVQEEIDRVIGGRQPVVEDRKKLPYTDAVIHEIQRLANIVPMNLPHVTSCDVTFNGYFIKK 59976
59893 GTTVIPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVKRDAFMPFSA 59753
59675 GRRVCLGESLARMELFLFFASLLQSYRFTTPPGVSEDELDLKGTVGVTLNPSPHKLCAIKRF 59490

>CYP2K18.e ctg12742 MISSING FIRST TWO INTRONS EXON 3 IS DUPL. MAY BE A PSEUDOGENE
93% to 2K19, 91% to 2K21 zfishK-a1004a03.p1c (100% over 29aa) also matches 2K19, 2K20
78359 MAVVESLLQFASTGTLLGALLLFLVLYLVSSGSESQKEGKEPPGPKPLPLVGNLLTLDLTRPFDT 78165
78164 FFKLSKTYGNVFQVYLGPEKAVVLVGYKTVKEALVNYAEEFGDREIGPGFSIMNDEH 77912
77911 GILFSNGENWKEMRRFALSNLADFGMGKRRSEEK 
75750 GILFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKF 75604
75522 GKPFDTTQPVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSISMX 75364
75253 LYDIFPWLGPFLKNKRIIVENIIQSRVQMTKLITALLETLNPNDPRGFVDSFLIRKXX 75086
74916 XQKSGKKDSYFHEENLMMTVTNLFIAGTDTTGTTLRWGLMLMAKYPHIQ 74773
74686 XRVQEEIDRVIGGRQPVVEDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKK 74504
74413 GTTVVPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVRRDAFMPFSA 74273
73457 GRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELDLKGIVGITLNPSPHKLCAIRR 73275

>CYP2K19.f ctg12742 91% to 2K21 AF221128 (1 aa diff) zfishC-a678c11.p1c (near perfect)
90000 MAVVESLLQFASTGTLLAALLLFLVLYLVSSGSQKEGKEPPGPKPLPLLGNLLTLDLTRAFDTFFE 89803
89722 LSKTYGNVFQVFLGPRKTVVLVGYKTVKEALVNYAEQFGDREIGPGFRIMNDXX 89567
89232 GILFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFX 89086
89004 GKPFDTTQPVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSVSMX 88846
88704 XHEMFPWVGPFLKSKRIIVENIIQSRAQMTKLITALLETLNPNDPRGFVDSFLTRKXX 88540
88368 XQKSGKKDSYFHEENLIMTVTNLFVAGTDTTGTTLRWGLMLMAKYPQIQ 88225
88134 XRVQEEIDRVIGGRQPVVEDRKKLPYTDAVIHEIQRLANIVPLSLPHKTTSDITFNGYFIKK 87952
87861 GTTVVPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVKRDAFIPFSA 87721
84188 GRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELDLKGIVGITLNPSPHKLCAIRR 84006

>CYP2K20.g ctg12742 88% to 2K19 and 2K21 zfishC-a1699d01.q1c (100% over 57aa)
AF221128 (1 aa diff) zfishC-a678c11.p1c (near perfect) zfishC-a1101c09.q1c (100% over 39aa)
104280 MAVVESLLQFASTSALLGALLLLLVLYLASSGSTSQKEGKEPPGPKPLPLVGNLLTLDLTRSFDTFFE 104077
103997 LSKTYGNIFQVFLGHRKTVVLVGYKTVKEALVNYAEVFGDREIGPGFKXXXXX 103854
102358 GILFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFX 102212
102123 GKPFDTTQPVNYAVSNIISSIVYGSRFEYIDPRFTEMVARANENVRVGGSFSMX 101965
101852 IYNIFPWLGPFLKNRAVVVKNITQNRAEKKKLITALLETLNPHDPRGFVDSFLIHKXX 101685
101522 XQKSGKKDSYFHEENLMLTVANLFAAGTDTTGTTLRWGLMLMAKYPHIQ 101379
101300 DRVQEEIDRVIGGRQPVVDDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKK 101118
 97108 GTTVVPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVKRDAFMPFSA 96968
 92153 GRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDALDLKGIVGITLNPSPHKLCAIRR 91971

>CYP2K21.h ctg12742 91% to 2K19 zfishB-a619a12.q1c (near perfect)
112093 MAVVESLLQFASTGTLLGALLLFLVLYLVSSGSGSQKEGKEPPGPKPLPLLGNLLTLDLTRAFDTFFE 111890
111821 LSKTYGNIFQVYLGPKKTVVLVGYKTVKEALVNHAEAFGDREIGPSFRIMNDXX 111666
109983 GIVFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFX 109837
109744 GKPFDTTEPVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSISMX 109586
109441 LYNMFPWLGPFLKNKRIVVRNIIQSRAQMTKLITALLETLNPNDPRGFVDSFLIHKXX 109274
109110 XQKSGKKNSYFHNENLMMNVANLFVAGTDTTGTTLRWGLMLMAKYPQIQ 108967
108879 XRVQEEIDRVIGGRQPAVEDRKKLPYTDAVIHEIQRFANIVPLNLPHTTSCDITFNGYFIKK 108697
108484 GTTVIPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVKRDAFMPFSA 108344
107905 GRRICLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELDLKGIVGITLNPSPHKLCAIRR 107723

>CYP2K21-de1.i ctg12742 PSEUDOGENE PARTIAL EXON 1?
113358 MAAVETLLQFASTGSLLSALLLLLVWYLVSSESTYQKKGKEPPGPKPLPLLGNLLT 113191 

>CYP2K22 ctg11670 zfishC-a643a08.p1c MISSING EXON 6 GREATER THAN 95% to 2K7. 9aa diffs 
in the first exon, only 3 aa diffs in the rest
33920 MALVAALLPGLGFTVSTILAFLLLFLVISYFFSSKDKGKYPPGPKPLPVLGNLHILDLKNTYMSLWK 34120
37393 LSKQYGPVYTVHMGPRTVVVLSGYKVVKEALVNLSEEFGERDISPIFQDFNEGY 37554
37635 GIVFSNGENWKEMRRFALSNLRDFGMGKKRSEELITEEIKYLKEEIERFX 37781
39367 GKPFETKLPLAMAISNVIALIVYSIRFEYNSPKFHRAIVRANENAKLVGSPSVQ 39528
42486 LYNMFPWLRLFVANQKRVVDNVQESFKQIGEIVNGLKKTLNPQSPRGIVDKFLIQQQK 42659

45851 AKVHDEIDSVIGERQPVPDDRKNLPYTDAVIHEIQRFADILPIGLLRQTSCDVHLNGYLIKK 46036
46115 GTSVFPLIASVLRDENEWETPDSFNPKHFLNKQGQFVKKDAFMPFGA 46255
49040 GRRLCIGESLARMELFLFFTSLLQHFCFTPPPGVSEDELDLTPVVGFTLSPMPHKLCAVKRF 49225

>NA54273 exons 5, 6, 7 new 75% to 2K7
125599 LESLAVVLQRRDWENPFKQSGEIMNGLKNTLNPQDPRGIADKFLIRQ 125459
125370 XQDSGKTDTYYNSNNLLSTINNLFGAGTDTTVTTLRWGLLIMAKNPEIQ 125227
125068 XKVQDEIKRVIGDRQPVPDDRKNLPYTDAVIHEVQRFADVLPIGSPHQTTCDVHLNGYLIKK 124886

>NA25235 exons 3,4,5 partial 5 aa diffs to 2K20
1349 GILFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKF 1495
1590 GKPFDTTEPVNYAVSNIISSIVYGSRFEYTDPQFTEMVARANENIRVGGSFSM 1748
1881 IYNIFPWLGPFLKNRAVVVKNVTQNRAEKKK 1973

>CYP2N13 ctg24224.a Z35723-a834b06.q1c zfishC-a2756d10.q1c 55% to 2N2 58% to 2N10
1168693 MAYTAILETLDVKGILLFMVAFLLVADYLKNRNPPKYPPSPFSVPLLGNIFNVDSKEPHLYLTK 1168514
1168189 LGHAYNNIFSLRLGSDKTVFITGYKMVKEALVTQAENFVDRPNSPVLARVYSGNA 1168049
1165570 GLFFSNGEMWKKQRRFALSTLRNFGLGKKTMELAICEESRFLLEEIDEQK 1165421
1164430 GAAFDPTILLYNAVSNIICQMVFGQRFDYADHQFKTMLKYISKSIQLEGSVWGQ 1164269
1164131 IYEAFPAIMKHLPGPHNDIFSNYDLLKSFVHEVIVKHKAKLDPSEPRDYIDTFLIEMKE 1163955
1163864 KPHERVNGFEEPNLVACVLDLFLAGTESTSNTLCWGLIYLIMYPDVQ 1163724
1163117 EKVQEEIDRVIGNSREPSIADKPNMPYTEAVIHEIMRFGDVIPLNGLRVAARDTTLGECFIPK 1162929
1162206 GTTVLPILHSVLFDENEWETPYKFNPGHFLDKEGKFVRRDAFMPFSA 1162066
1161562 GKRVCLGEQIARIELFLFFVSLFRKFRFSATEGEKLNMDGVIGITRTPHPFKICATAR 1161389

>NA35153 heme region CYP2N like fragment 70% to 2N10 Z37249-a749c05.p1c
MSSRVYSRGSPLMEEKILTEVTVMIERLRKTIACVDMQNVFDTSIGSIINSLIFGYRFDESEF 
(gap)
GSLKKVEELVPFSIGKRQCPGEGLAKMELFLFFANLFNTFDIQLHESNLNASIEKDSGITMKAKNYKITLKERF*

>CYP2P6 ctg24224.g NEW 77% TO 2p9
1209157 MDLLHIYEWIDIKAVLFFACVFLLLSNYIQNKTPKNFPPGPWPLPIIGNLYHIDFNKIHLEVEK 1209348
1209657 LSEKYGSVVSVHLFGQRTVILNGYKQVKEVYIQQGDNVADRPELPMIHDIAGDN 1209818
1209977 GLVAPSGYKWKQQRRFALSTLRNFGLGKKSLEPSINLECHYLNEAISNEN 1210126
1210235 GRPFDPHLLLNNAISNVICVLVFGNRFDYSDHHFQTLLNNINEAMYLDGTIWAQ 1210396
1210482 LYNSHPRIMRLLPGPHKKNITLWNKVIDFARERVKEHRVDYDPSNPRDYVDCFLAEMEK 1210658
1210736 LKDDTAAGFDVENLCICTLDLFVAGTETTSTTLSWSLLYMIKYPEIQ 1210876
1212110 AKVQEEIDRVIGSSRQPSVSDRDNMPYTNAVIHEIQRFGNIAALNLPRAAVKDIQVGKYLIPK 1212298
1212390 GTIVIGNLTSVLFDESEWETPHSFNPGHFLDAEGKFRRRDAFLPFS 1212527
1213310 GKRVCLGEQLARMELFLFFTSLLQHFTFSSPAGVEPSFNYKLGTTRAPKPFKLCAVSR 1213483

>CYP2P7 ctg24224.h  81% to 2p9,  62% to 2P3 (Fundulus)
1214731 MDVLQFYKWLDIKTVLVFLVVFLFLSDYIRNKSPKNFPPGPWSLPFIGHIHHIEHKKVHLQFLK 1214922
1216466 FAEKYGKIFSIRLFGPRIVVLDGYKLVKEVYLQQGDNLADRPILPMFYDITEDK 1216627
1217670 GLIGSNGYKWKHQRRFALSTFRTFGLGKKSLEPSILLECSCLNDAFSNEQ 1217819
1217891 XPFDPRLLLNNAVSNVICALVFSNRFDYSDHHFQTLLKHINEVLYLEGTVWAQ 1218046
1218134 LYNFFPWLMRRLPGPHQKIFVLLNKVIDFVREKVNEHRVDYDPSNPRDYIDCFLAEMEK 1218310
1218399 LKDDTAAGFDVENLCICTLDLFVAGTETTSTTLYWGLLYIIKYPEIQ 1218539
1218632 AKVQQEIDAVVGGSRQPSVSDRDNMPYTNAVIHEIQRMGNIVPLNVFRITVEDTQIGEYSIPK 1218820
1218907 GTLVIGSLTSVLFDESEWETPHSFNPGHFLDAEGKFRRRDAFLPFS 1219044
1219144 GKRVCLGEQLARMELFLFFSSLLQRFTFSPPAGVEPSLDYKLGGTHSPQPYKLCAVPR 1219317

>CYP2P8 ctg24224.i   90% TO 2p9
1221362 MDLWYLYEWIDIKSILIFLCVFLLLGDYIKNKAPKNFPPGPWSLPIIGDLHHIDNSKIHLQFTK 1221553
1221722 FAERYGNIFSFRLFGPRIVVLNGYNLVKEVYIKQGDNLADRPVLPLFYEIIGDK 1228152
1221974 GLILSSGYKWKHQRRFALSTLRNFGLGKKSLEPSINVECGFLNEAISNEQ 1222123
1222203 GRPFDPRLLLNNAVSNVICVLVFGNRFDYSDHHFQTLLKNISEAVYLEGSICNQ 1222364
1224317 LYNMFPWLMERLPGPHKTIITLWRKVTDFVREKVNEHRVDYDPSNPRDYIDCFLTEMEK 1224493
1224582 LKDDTAAGFDVENLCICSLDLFVAGTETTSTTLYWGLLYMIKYPEIQ 1224722
1224812 AKVQEEIDAVVGGSRQPSVSDRDNMPYTNAVIHEIQRMGNIAPINLARSTSEDTQIGNYSIPK 1225000
1225184 GTMVTSNLTSVLFDESEWETPHSFNPGHFLDAEGKFRRRDAFLPFS 1225321
1225421 GKRVCLGEQLARMELFLFFSSLLQRFTFSPPAGVEPSLDYKMGGTHCPKPFKLCAVPR 1225594

>CYP2P8-de7,8 ctg24224.j  EXONS 7,8
1226868 PSVSDRDNMPYTNSVIHEIQSIGNIGPLNVFGITVK 1226975
1227088 GTLVIGSLTSVLFDESEWETPHSFNPGHFLDAEGKFRRRDAFLPFS 1227225

>CYP2P9 ctg24224.k   98% (7 AA DIFFS) TO 2p9
1227637 MDLWYLYEWIDIKSILIFLCVFLLLGDYIKNKAPKNFPPGPWSLPIIGDLHHIDNSKIHLQFTK 1227831
1227991 FAERYGNIFSLRLFGPRIVVLNGYNLVKEVYIKQGDNLADRPVLPLFYEIIGDK 1228131
1228249 GIVLSSGYKWKHQRRFALSTLRNFGLGKKSLEPSINLECGFLNEAISNEQ 1228398
1228473 GQPFDPRLLLNNAVSNVICVLVFGNRFDYSDHHFQTLLKHINEAIYLEGGICAQ 1228634
1228798 LYNMFPWLMQRLPGSHKKVITLWKKVIDFIRQKVNEHKVDHDPLNPRDYIDCFLAEMEK 1228974
1229073 LKDDTAAGFDVENLCICTLDLFVAGTETTSTTLYWGLLYMMKYPVIQ 1229210
1229290 AKVQEEIDRVVGGSRHPSVSDRDNMPYTNAVIHEIQRMGNIIPINVTRTTSEDIRIGKYSVPK 1229475
1229629 GTMVTSNLTSVLFDESEWETPHSFNPGHFLNAEGKFRRRDAFLPFSL 1229769
1229866 GKRVCLGEQLARMELFLFFSSLLQRFTFSPPAGVEPSLDYKLGATHCPQPYKLCAVPR 1230039

>CYP2P9 BC056816, NM_200620 61% to CYP2P3 zfishK-a583c07.p1c zfishC-a1218e09.p1ca
MDLWDLYEWIDIKSILIFLCVFLLLGDYIKNKAPKNFPPGPWSLPIIGDLHHIDNSKIHLQFTK
FAERYGNIFSLRLFGPRIVVLNGYNLVKEVYIKQGDNLADRPVLPLFYEIIGDK
GIVLSSGYKWKHQRRFALSTLRNFGLGKKSLEPSINLECGFLNEAISNEQ
GQPFDPRLLLNNAVSNVICVLVFGNRFDYSDHHFQTLLKHINEAIYLEGGICAQ
LYNMFPWLMQRLPGSHKKVITLWKKVIDFIRQKVNEHRVDHDPLNPRDYIDCFLAEMDK
LKDDTAAGFDVENLCICTLDLFVAGTETTSTTLYWGLLYMMKYPGIQ
AKVQEEIDRVVGGSRQPSVSDRDNMPYTNAVIHEIQRMGNIIPINVTRTTSEDIRIGKYSVPK
GTMVTSNLTSVLFDESEWETPHSFNPGHFLDAEGKFRRRDAFLPFSL
GKRVCLGEQLARMELFLFFSSLLQRFTFSPPAGVEPSLDYKLGATHCPQPYQLCAVPR

>CYP2P10 BC049521, NM_201511 84% to CYP2p9 zfishG-a2632g08.q1c
MDMFYFYEWVDIKSILIFLCVFLLLSDYIKNKAPKNFPPGPWSL
PFIGDLHHIDPNKIHLQFTEFAEKYGKIFSFRLFGSRIVVLNGYNLVKEVYTQQGDNL
ADRPTLPITSAIIGDNRGLVASSGYKWKHQRRFALTTLRNFGLGKKNLELSINFECGF
LNEAISNEQGRPFNPRLLLNNAVSNVICVLVFGNRFEYSDHHFQNLLNKINESVYLEG
SIFVHLYNMFPWLMQLLPGPHKKLITLWQRVTDFVREKVNEHRVDYDPSSLRDYIDCF
LAEMEKHKDDTAAGFDVENLCMCTLDLFVAGTETTSTTLYWGLLYMIKYPEIQAKVQQ
EIDAVVGSSRQPSGSDRDNMPYTNAVIHEIQRMGNIIPLNVVRTTSEDTRIEKYSIPK
GTLVIGSLTSVLFDESEWETPHSFNPGHFLDAEGKFRRRDAFLPFSLGKRVCLGEQLA
RMELFLFFSSVLQRFTFSPPAGVEPSLDFKMGFTRCPKPYKLCAVPR

>CYP2P10 ctg24224.l   3 AA DIFFS TO 2P10
1232262 MDMFYFYEWVDIKSILIFLCVFLLLSDYIKNKAPKNFPPGPWSLPFIGDLHHIDPNKIHLQFTE 1232411
1233540 FAEKYGKIFSFRLFGSRIVVLNGYNLVKEVYTQQGDNLADRPTLPITSAIIGDNR 1233677
1233779 GLVASSGYKWKHQRRFALTTLRNFGLGKKNLELSINFECGFLNEAISNEQ 1233928
1234024 GRPFNPRLLLNNAVSNVICVLVFGNRFEYSDHHFQNLLNKINESVYLEGSIFVH 1234173
1237098 LYNMFPWLMQLLPGPHKKLITLWQRVTDFVREKVNEHRADYDQSSLRDYIDCFLAEMEK 1237274
1237383 HKDDTAAGFDVENLCMCTLDLFVAGTETTSTTLYWGLLYMIKYPEIQ 1237523
1237610 AKVQQEIDAVVGSSRQPSGSDRDNMPYTNAVIHEIQRMGNIIPLNVVRTTSEDTRIEKYSIPK 1237798
1239047 GTLVIGSLTSVLFDESEWETPHSFNPGHFLDAEGKFRRRDAFLPFSL 1239184
1239282 GKRVCLGEQLARMELFLFFTSVLQRFTFSPPAGVEPSLDFKMGFTRCPKPYKLCAVPR 1239455

>CYP2P10-de9 ctg24224.m   3 AA DIFFS TO 2P10
1242741 MELFLFFSSLLYF 1242779
1242772 FTFSLPADVKPSLGYKMGAHTVP 1242840

>CYP2P-se1 ctg24224.n 
1243476 MDMLHFYEWIDIKSILIFVCVFLLLSDFIKNKTPKNFPPGPWSLPIIGDIHHIDPSKLHLQLSE 1243667

>BI468047 EST00457 Atlantic salmon 77% to CYP2P10
1   DPSSPRDFIDCFLNEIEKCEDDTRAGFNLENLSFCTLDLFVAGTETTSTTLYWGLLFMIN 180
181 YPEIQAKVQAEIDAVVRSSRQPSMEDRDSMPYTDAVIHETQRMGNIIPLNVSRMATKDTE 360
361 VGGYTIPKNTIVLGTLQSILFDESEWETPHTFNPGHFLDQEGKFRKRDAFLPFSLGKRVC 540
541 PXEQLAKMELFLFFTSLLQRFTFFSPPGVEPSL 639

>CYP2R1 AL954331.8 zfishG-a628h11.q1cz 77% to 2R1
31079 MISIKRLTSPLSLSW
      EQTLICLLGLFTTLLILLVIRQLVKQRRPRGFPPGPTPLPIIGNM 30900
30899 LSLATEPHVYMKRQSDIHGQ (0) 30840
29596 IFSLDLGGIPTVILNGYDAIKECLYHQSEVFADRPSLPLFQKMTK
27563 KLAVNCFRYFGTGQRMFERISEECLYFLDAIDQHQGKPFNPKHLVTNAVSNITNLIIFG
27386 QRFTYDDGDFQHMIEIFSENVELAASSWAFLYNAFPWMEYLPFGKHQRLFRNANEVYKFL
27206 LQIIRRFSQGRVPQSPQHYIDAYLDEMEQSTPDKATSFSQDNLIFSVGELIIAGTETTTN
27026 CLRWAMLYMALYPRIQ 26979
      EKVQMEIDSVLNGRQPAFED 26821
26820 RQRMPYVEAVLHEVLRLCNIVPLGIFRATSQDAVVRGYTIPKGTMVITNLYSVHFDEKYW 26641
26640 SDPSIFCPERFLDCNGKFIRHEAFLPFSI 26554 ()
26470 GKRHCLGEQLARLEMFLFFTTLLQRFHLQFSEGFIPSLSAKLGMTLQPQPYSICAIRRQQ* 26288

>CYP2U1 ctg13442 63% to 2U1 fugu 57% to 2U1 human zfishG-a1404f04.q1c     
       MDVSAGLLLEYVFSP
224891 ANIAGLTALVLVFYVLQEYQWHQTYANIPPGPKPWPIVGNFGGFLVPPLIIKRFXKNSQE 225070
225071 FAKVVSNPLSPQAGLIEMSKLYGNIFSIFVGPQLMVVLTGYDAVRDAMLNHTETFSDRPH 225250
225251 IPLVTIITKRK 225283
227637 GIVFAPYGPLWRTNRRFCHSTLRSFGFGRMSLEPCIHEGLAIIKTELQSLIETAGPSGID 227816
227817 LTPLISNAVSNIISLMSLGQRFHHEDKEFRNMRDLMSHGLEISVNTSILLVNVFPWLYYL 227996
227997 PFGVFKELRRAELDITAFLKRIIARHRATLDPENPRDFIDMYLVEMLAKQKEGSSEENLF 228176
228177 SEDDLFYIIGDLFIAGTDTTTNSMLWSILYMSLYPDVQ 228290
230823 EKVQKEIDAVVGSERVPSLTDKSSLPYTEATIMEVIRMTVVVPLSIPHMASETT 230981 (1)
231602 EFRGFTIPKGTVIIPNLWSVHRDPTVWENPDDFNPSRFLDDQGKILRKDCFIPFGL 231769
234247 GRRVCMGEQLAKMELFLMFTSLMQTFTFRFPEGATAPSMHGRFGLTLAPCPFTVCVKTR* 234426

>CYP2U1-de1 ctg13442 Duplicate exon 1 partial
226215 QLMVVLTGYDAVRDAMLNHTETFSDRPHIPLVTIITKRKG 226334

>CYP2V1 AB026158 zfishC-a1007a08.p1c zfishK-a1019e01.q1c
MALENILLHLNSKVWTDAGTILLLFILFLLVSVKLRNRNKPTKT
FLLGPTPLPFIGNVFNLDTSQPHICLTKMSDHYGNIFSLRLGSLNTVVVNTYSMVKKV
LNDQGNSFMYRPSNDITERILSKCQGLTFNNGYSWKQHRRFTLSTLKFFGVGKRSLEF
IIMEEYKFLHQSILDTNGLPFNPHYIINNGVSNIICSMVFGRRFEYTDQRFLNMLSLI
SKALKLQTSVFIQLYAAFPRLMDLLPGPHKELFSCFHQVRAFIKEEVDKHRADWDPSS
PRDFIDCYLTEIEKMKDDLEAGFHDEGLQYAVLDLFVAGTETTSTTLLWAFVYMMKYQ
KSKKVQAEIDKVVGRYRRPSMDDRPCMPYTDAVIHEIQRMGNVVPLSVPRMTNEDTLL
EGLFHSLRVLQIIPNLTSVLFDQTKWKTQHSFDPQNFLNAQGKLKSLKLLSPFSLGKR
SCPGESLARMELFLFFTSFLQSFSLSAPDETQTSLDFKCGMTLSPKPFKICFTPR

>CYP2V1 ctg24224.e SOME DIFFERENCES WITH AB026158 AT INTRON BOUNDARIES ETC.
1198232 MALENILLHLNSKVWTDAGTILLLFILFLLVSVKLRNRNKPHKNLPPGPTPLPFIGNVFNLDTSQPHIDLTK 1198447
1200610 MSDHYGNIFSLRLGSLNTVVVNTYSMVKKVLNDQGNSFMYRPVNDITERISKCQ 1200771
1200844 GLTFNNGYSWKQHRRFTLSTLKFFGVGKRSLEFIIMEEYKFL 1200969
1202144 GLPFNPHYIINNGVSNIICSMVFGRRFEYTDQRFLNMLSLISKALKLQTSVFIQ 1202305
1202415 LYAAFPRLMDLLPGPHKELFSCFHQVRAFIKEEVDKHRADWDPSSPRDFIDCYLTEIEK 1202591
1202711 KKDDLEAGFHDEGLQYAVLDLFVAGTETTSTTLLWAFVYMMKYPEIQ 1202851
1203025 EKVQAEIDKVVGRYRRPSMDDRPCMPYTDAVIHEIQRMGNVVPLSVPRMTNEDTILEGYFIPK 1203213
1203555 GTQIIPNLTSVLFDQTKWKTQHSFDPQNFLNAQGKFEKPEAFIPFSL 1203695
1203789 GKRSCPGESLARMELFLFFTSFLQSFSLSAPDETQTSLDFKFGMTLSPKPFKICFTPR 1203962

>CYP2P9 LIKE PSEUDOGENE ctg24224.f PSEUDOGENE exons 1, 2, 7, 8, 9
1204822 MDLLHLYEWIDIKTILLFTLVFLLLGDYIKNKLPKTFHP 1204938
1204935 PGPWSLPIIGDVHINHKKIPLQLEK 1205009
1205114 FAEKYGNVLSIQILGIRFVVLIGYKTVKEFYAQGDSLTDRPILPIFYDIFGDK 1205272
1206680 ANVQEEIDGVVGGS----LSDRDNMPHTIAAIHKLHKL*VIRMGNIVPLNLACVTSKETQTGKYSIPK 1206871
1207618 GTLVIGSLTSVLFDESEWETPHSFNPGHFLDAEGKFRRRDAFLPFS 1207755
1207922 GKRRCPGEQLA----------------FSLHVGVEPSFDYKVG 1208002

>CYP2X6 ctg22265.a 66% to CYP2X1
708019 MLGSSLLVVICILLIFFLIRVKKPKNFPPGPPPVPIFGNLLQLNLANPLKDFEK 707858
707784 FAEKYGEIFSLYTGSRPAVILNSFAVIKEALVTKAQDFSGRPQDFMISHATENKGN 707617
705571 IVLADYGPVLKGHRRFALMTMRNFGLGKQSMEERILGEISHVVDYLDKNA 
       GKRVDPHIMFHNVASNVISLLLFGCRFDYNSEFLQCYIQLINEISKIINGPWNM 705149
703459 IYDTFPLLRILPLPFKKAFDHVKVIKSMNLKLIDEHKSTRVPGEPRDFIDCYLDELDK 703286
703161 GKNCVSTFSEDKLLMSIMDLHFAGTDTISNTLLTAFLYLMNHPEVQ 703024
702766 VKCQQEIDDVLEGKDQVTYEDRHNMPYTLAVIHEVQRVANTVPLSVFHCTTRDTELMGYSIPK 702578
702500 GTIIIPNLTRVLKEEGQWKFPYEFNPANFLNEQGQFEKPEAFIPFST 702360
701098 GLRMCLGEGLARMELFLIFVTLLRRFQFVWPEDAGKPDYTPVFGLTLTPKPYRMHIRRRETVKQ* 700904

>CYP2X7 ctg22265.b CYP2X1 Missing C-term CK030199 AI959373
BC053412 AI959373 fd08g05.y1 zfishC-a2684d06.q1c
ctg11087 = BC053412 FILLS IN exons 3,4 in a GAP IN ctg22265
718880 MLEVSVLILICIFLVFFLIRIKRPKNFPPGPPPVPIFGNLLQINMVDPLKEFER 718719
718641 LAEKYGNIFSLYTGSKPAVFLNNFEVIKEALVTKAQDFSGRPQDLMISHL 718492 TGNKG
670408 VVLADYGPLWKDHRRFALMTLRNFGLGKQSMEERILGEISHIVDFLDKNT 670557
670648 GKTVDPQIMFHNIASNVINLVLFGCRFDYNNEFLRGYIQRIAENLRILNGPWNM 670809
717005 IYDTFPLLRILPLPFKKAFDNVKIIKSMNRKLIDEHKSTRVPGQPRDFIDCYLDELDK 716832
716723 VKNCVST 716703 716703 FSEDQLIMNIMDMSFAGTDTTSNTLLAAFLYLMNHPDVQ ()
716439 VKCQQEIDDVLEGKDQVTYEDRHNMPYTLAVIHEVQRVANIVPLSVLHCTTRDTELMGYSIPK 716251 ()
716170 GTVIIPNLTVVLKEEGQWKFPHEFNPANFLNEQGQFEKPEAFIPFST 716030
713418 GPRVCLGEGLARMELFLIFVTLLRRF 713341
       QFVWPEDAGKPDYTPVFGLTMTPKPYRMHIRRRNTVKQ

>CYP2X7-de9a    ctg22265.c CYP2X1 pseudogene? C-term 92% to 2X.b zfish41361-135c06.q1c zfish45283253h10.q1k zfish43795-291e06.p1c
720930 LGEGLARMELFLVFVTLLRRFQFVWLEDAGKPDYTPVFRHTMTPKPYRMHIRRR 720769

>CYP2X7-de9b    ctg22265.d CYP2X1 pseudogene? C-term 87% to 2X.b
727710 GPRVCLGEGLARMELFLVFVTLLRRYKFVWPRDAGKPDYTPVFGITMTPKPYRMLIRRRDTVQ 727519

>CYP2X8 ctg21275 87% to 2X.a
1267572 MLGSSVLVLICILLVFLLIRIQRPKNFPPGPSPLPIFGNLLHFNLANPLKEFER 1267411
1267339 FAEKYGNIFSLYTGSRPAVFLNSFAVIKEALVTKAQDFSGRPQDFMISHLTECKGN 1267172
1263893 VVLADYGPLWKDHRRFALMTLRNFGLGKQSMEERILGEISHVVGYLDKNI 1263744
1263630 GKTVDPQVMFHNVASNVISLVLFGRRFDYNSETLQCYIQLITEISKILNGPWNM 1263469
1262072 IYDTLPFLRILPLPFKKGFDHVKVLKGMNLKLIDEHKSTRVPGKPRDFIDCYLDELDK 1261899
1261775 RKNEVSTFSEDQLLMYILDLYFAGTDTTSNTLLTAFLYLMNHPEVQ 1261638
1261335 VKCQQEIDDVLEGKDQVSYEDRDNMPYTLAVIHEVQRVANTVPLSVFHCTTRDTELMGYSIPK 1261147
1261074 GTLIIPNLTIVLKEEGQWKFPHEFNPANFLNEQGQFEKPEAFIPFST 1260934
1269368 GPRVCLGEGLARMELFLVMVTLLRRFQFVWPNDAGKPDYTP
1269244 VYGVTLTPQPYRMHIKRRETVRX 1269179

>CYP2X9 ctg9731 exons 1-4 67% to 2X6 first 39 aa = 2X6 100%, FRAMESHIFT IN EXON 3
66640 MLGSSLLVVICILLIFFLIRVKKPKNFPPGPPPVPIFGNMLQLNINNPLKDFER 66479
66305 LANRYGNIYSLYFGSKPWVVLNGFEALKEALVTKAVDFAGRPQDLMVNRVTKGGGE 66138
65961 VILSDYGPSWKE  HRRFALMTLRNFGLGKQSMEERILGEVSHIIDKLEKR 65819
65727 GTAFDPQTMFHNAASNIICIVLFGSRYDYDDEFLKLFIHLYTENAKIANGPWAM 65566
>ctg21275 exons 5-9 77% to 2X.b trace CF996180 joins these two contigs
1272272 IYDTFPMFRYLPLPFRKAFANASKARELSTQLVEEHKKTWVPGEPRDFIDCYLDELDK 1272099
1271302 RGNDGSSFSEAQLILYVLDLHFAGTDTTSNTLLTGFLYLMTHPEVQ 1271165
1269858 AKCQQEIDDVLEDKDQASYEDRHSMPYTQAVIHEVQRVANTVPLSVFHCTTKDTELMGYNIPK 1269670
1269601 GTFVIPNLGSALKEEGQWKFPHEFNPANFLNEQGEFEKPEAFVPFSA 1269461
1259306 GPRVCLGEGLACTELFLVFVTLLRRYKFVWPRDAGKPDYTPVFGITMTPKPYRMHIRWRNTVKQ 1259115

>CYP2X10 ctg24117.a 55% to 2X.b
57088 MLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDK 56927
56847 FAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGK 56680
56436 VIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESA 56287
56129 GKSIDPQHLYHQAASNIIASIIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAM 55968
55706 LYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEME 55536
55465 KSDTHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQ 55328
54962 EQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPK 54774
54580 GTIIIPYLSSSLREESQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSA 54440
54228 GPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPR 54052

>CYP2X11 ctg24117.b zfishI-a36g12.q1c EXONS 1-7 85% to CYP2 Length = 544
80259 MLTALVLLCLGAFLLYLQVRIRRPKDFPPGPAPVPFFGNLLQLNRINPIKDLDK 80420
80510 FAQHYGSIYGIYIGSKPAVVLTGQKMIKEALITQAAEFAGRPNHMMISHITRSKGS 80677
80848 VIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESA 80997
82938 GKSIDPQHLYHQAASNIIASVIFGSRFNYKDEYFQTLIQTMEKLTKIAIGTWAM 83099
83317 LYEIAPVLRIFPLPFWKAFHYFEKITRHSLKVVEEHKKSFVAGEPKDLIDCYLEEMKK 83490
83572 RADQRTTFDEAQMVTLLFDLYLAGTETTSNTLRTLTLF 83685
88976 EQCQREIDEVLGARDHVTYEDRNDMHFVQAVIHEGQRVADIVPLNVFHTARTDTQLRGYSIPK 89164
92540 GTIIIPYLSSSLREESQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSA 92680
92791 GPRVCLGENLARMELFLILVTVLRKFRLVWPKDAGEPDFTYIYGGTQSLKPYPMIVKLR 92967

>CYP2X11-de1 ctg24117.c EXON 1 
94557 MLTALVLLCLGAFLLYLQLRIRRPRNFPPGPAPVPIFGNLLQLNHINPIKDLDK 94718
 
>NA39705 exon 5 100% to NA54102 exon 5 a CYP2X fragment
1225   LYEIAPVLRIFPLPFHKAFQYFEQITNHVLKVVEEHKTSRVAGEPRDLIDCYLEEMNR 1052

>NA54102 EXONS 5,6,7    4 diffs to zfishK-a181a04.p1c a CYP2X fragment
110480 LYEIAPVLRIFPLPFHKAFQYFEQITNHVLKVVEEHKTSRVAGEPRDLIDCYLEEMNR 110307
110196 RSDKHTTFDESQMVTLLFDLFIAGTETTSNTLRTLTLYMTYTHIQ 110059
107987 EQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIVPLTMFHTARTDTQLRGYSIPK 107799

>NA50719 EXONS 8,9 = AL925560 cDNA a CYP2X fragment
    RGYSIPK
606 GTIIIPYLSSSLREESQWKFPHEFNPQNFLNEKGEFVKNEAFMPFSA 746
857 GPRVCLGENLARMELFLILVTVLRKFRLVWPKDAGEPDFTYIYGGTQSLKPYPMIVELR 1033
    TPGETHEYAN*

>CYP2X1   Ictalurus punctatus (catfish) GenEMBL AF315346.1
MLGSWLLVVFCVCLLFLFIRIQRPKNFPPGPRPIPIFGNLFQFN
IKNPLKDFEKLAEQYGNICSLYIGTKPAVVLNGLKVIREALVTKSADFSGRPQNMLKD
VTEGKGIVIADYGRQWKEHRRFALMTLRNFGLGKQSMENRILGEIEHLVAKLEKYAGS
SMYPQTLFHDAASNIIYLVLFGTRYDYGDETLKVYVRLYSENAKLANGTWSIIYDALP
ILRSLPLPFKKAFDNYSTLKILTANMINKHRTTRVPGKPRDLVDCYLDEIDKKDNEST
FSEEQLVVYIMNLHIAGTDTTSNTLLTSILYLMAHPDIQKRCQKEIDVVLEGNSQPSF
EDRHNMPYTQAVVHECQRIARTVPLSVFHCTTRDTELMGYTIPKGTMIIPNLSSVLSE
EGQWKFPHDFNPSNFLNEQGQFEKPEAFIPFSAGPRVCLGEGLARMELFLFLVTLLRR
FQFIWPEDAGEPDFTPIFGLTLTPKPYRMGVKLRQPAREK

>zfishC-a953b08.p1c Length = 570 13-93 66% to 2X1
 zfishG-a1843b03.p1cLength = 594 13-53
256 SSVLVLICILLVFLLIRIQRPKNFPPGPSPLPIFGNLLHFNLANPLK 396
471 HFKFAEKYGNIFSLYTGSRPAVFLNSFAVIKEA 569

>zfishI-a36g12.q1c Length = 590 9-59 58% to 2X1
263 TMLTALVLLCLGAFLLYLQVRIRRPKDFPPGPAPVPFFGNLLQLNRINPIK 111

>zfishG-a2651b11.q1c Length = 706 119-165 46% to 2C18 72% to 2X1
522 VLADYGPLWKDHGRFALMTLRNFGLGKQFMVDRILGEIAHVVGGLGK 662

>CYP2 AI496898 fb63f09.x1 70% to 2X1
486 GTIIIPYXSSSLREESQWKFPHEFNPQNFLNEKGKFVKNDAFMPFSAGPRVCLGENLARM 307
306 ELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPR 169

>zfishC-a1646d09.q1c Length = 573 389-437 75% to 2X1
318 KGTIIIPYLSSSLREESQWKFPHEFNPQNFLNEKGEFVKNEAFMPFSAG 464

>CYP2Y3 ESTs CK016257, CK869788, CK706387, CB891035    NA1608 zfishC-a921f03.q1c
zfishC-a1083h03.p1c zfishC-a123d10.q1c
30425 MELSSSLLLVLVLTVLMLIRWRRKENGLSLPPGPLALPLIGNLLTLDKSAPFKSFMK 30595 (0)
32151 WRKTYGSVMTVHLGPQRMVVLVGYETVKEALVDQAEDFAPRAPIAFMNRIVKGY (1?)
      GLAISNGERWRQLRRFTLTTLRDFGMGRKQMEQWIQEESRYLLKSFEETK 32519 (1?)
32651 SKPVDPTFFFSRTVSNVICSLVFGQRFDYEDKNFLQLLQIISKLLRFLSSPWGQ 32812 (0?)
33063 LYNIFPQVMERFSSRHHAILKDVENIRTFIRNKVKEHEQRLDFSDPSDFIDCFLIRLTQ 33239 (0?)
33356 EKDKRKLDTEFHKDNLMATVLNLFVAGTETTSTTLRYALMLLIKHPQIQ 33502 (1)
34553 EQMQREIDRVIGQNRIPTMEDRKSLPFTDAVIHEVQRYMDIVPLSLPHYAMKDITFRGYKIPK 34741 (0)
34907 DTVIIPMLHSVLRDEGQWETPWTFNPEHFLDSNGNFKKNPAFMPFSA 35047 (1)
35424 GKRSCVGESLARMELFLFTVSLLQKFTFSSPNGPDGIDLSPELSSFANMPRFYELIASPR* 35606

>CYP2Y4 EST AL916779 Zv3 NA1608, zfishC-a2916d05.p1c, zfishC-a2916d05.q1c
zfishC-a534g09.p1c zfishC-a534g09.q1c
42397 MELSSSLLLVLVLTVLMLIRWRRKENGLSLPPGPLALPLIGNLLTVETSAPFKSFMK 42567 (0)
      WSKSYXTVMTVHIGTQRMVVLVGYETVKEALVDQAEDFASRAPIPFTNRVLRGY
      XXXXTNGERWRQTERFTLTTLRDFGMGRKRMEQWIQEESRYLLKSFEETKSKPVDPLFFMSRAVSNVICS
      LVFGQRFDYEDKNFLQLLQIISNLMRFASSPWG
      QLYNIFPKVMEILPGRHHTMFGEIDDLKSSIMTII 44325
44326 KEHEENLDPSDPKDFIDCFLIRLNQ (0?)
      LQQEKHNPDT 44524
44525 EFHKENMFATSLNLFTAGTETTSTTLRYALMLLIKHPHIQ 
44989 EQMQREIDCVIGQNRIPTMEDRKSLPFTDAVIHEVQRCLDIAPLNVPHYALKDITFRGYKIPK 45177 (0)
      DTVIIPMLHSVLRD 45348
45349 EGHWETPWTFNPEHFLDSNGNFKKNPAFMPFSA 45447 (1)
46751 GKRVCVGESLARMEIFLFIVSLLQKFSFSSPNGPDSIDPSPELSSFGNMPRLYELIASPR 46930

>CYP2AA1 AF497969 74% to 2AA2
MLVGLVKLDLASVGLTLFLGLIFLVLFEIFRINSYKFRFPPGPT
PLPFVGNLPHFLKSPMEFIRSMPQYGEMTTIFFGRKPVIMLNTIQLAKEAYVQDAFSG
RPAIPLFDWITNGLGIVMVTFNNSWRQQRRFALHTLRNFGLGKKTVEDRVLEESRYLI
AEMLKEEGKSMNPQHALQNAISNIICSIVFGDRFEYDNKRFEYLLKTLNENIMLAGSA
AGQIFNLVPFIKHFPGPHQKIKQNADELLGFIRDEAKEHKQTLDPDSPRDFIDAYLLE
IEKQKSSKDSTFHEENLVVSASDLFLAGTDTTETTIRWGLINLIQNPDVQERCHEEIV
RVLGYDRLPSMDDRDKLPYTLATVYEIQRCANIAPNVMHQTILPTRLHGYDIPQGTII
LTNLAAIFSNKDHWKHPDAFNPENFLDENGHFSKPESFIPFSLGPRVCLGETLARTEL
FLFITALLQRIRFSWPPDAKPIDMDGIMGLVRSPQTFNVVCHSRDNVK

>CYP2AA1 ctg10776 98% TO 2AA1 AF497969 probably same gene 
297413 MLVGLVKLDLASVGLTLFLGLIFLVLFEIFRIHSYKGRFPPGPTPLPFVGNLPHFLKSPMEFIRS 297607
299386 MPQYGEMTTIFFGRKPVIMLNTIQLAKEAYVQDVFSGRPAIPLFDWITNGL 299538
303569 GIVMVTFNNSWRQQRRFALHTLRNFGLGKKTVEDRVLEESRHLIAEMLKEE 303721
303891 GKSMNPQHALQNAISNIICSIVFGDRFEYDNKRFEYLLKTLNENIMLAGSAAGQ 304052
304159 IFNLVPFIKHFPGPHQKIKQNADELLGFIRDEAKEHKQTLDPDSPRDFIDAYLLEIEK 304332
304418 QKPSKDSTFHEENLVVSASDLFLAGTDTTETTIRWGLINLIQNPDVQ 304558
307114 ERCHEEIVRVLGYDRLPSMDDRDKLPYTLATVYEIQRCANIAPNVMHQTILPTKLHGYNIPQ 307299
309993 GTIILTNLAAIFSNKEHWKHPDAFNPENFLDENGHFSKPESFIPFSL 310133
313591 GPRVCLGETLARTELFLFITALLQRIRFSWPPDAKPIDMDGIMGLVRSPQTFNVVCHSR 313767

>CYP2AA1-de1 ctg10776 
316625 MLAALLKLDLASVGLTLFLGLIFLVLFEIFRIYSYKGRFPPGPTPLPFVGSIPHFLNNPMGFIKS (0)
       LSQYGEMTTVYPGRKPAIILNTLQLMKEALV 317029

>CYP2AA2 AI657973 fc19c11.y1, AI958603 fc94a10.y1, AI544967 fb69h12.y1
zfishC-a1385b03.q1c, zfishC-a2172h09.q1c zfishG-a67c10.q1c
MFGALVKLDLSSVGLTLLLGLILLVLFEIFRIHSYKSRFPPGPTPLPFVGNLPHLLRDPMGFNRL (0) 
MAQYGEMSTMYLGKKPAIVLNTIQVAKEALVQEAFAGRPCLPAIDWTSNGC (1) 
GIIMATFNNSWKQQRRFALHTLRNFGLGKKSLESRVLEESQYLIAEMLKDE (1) 
GRPMNPQHAVQNALSNIICSIVFGDRFDYNNKRFEYLLKILNESIILTGSAAGQ (0) 
IFNFAPIIKHFPGPHQMINENANEVYSFVRHEVEEHRKTLDPGSPRDFIDGYLLEMEK (0) 
QKSNKDSTFHEDNLITTTVDLFLAGSDSTSSSIRWGLLFLIQNPDVQ (1)
ERCHEEIVQVLGYDRLPCMDDRDRLPYTLATVHEIQRCGNIAPFGLFHETVQPTKLRGYNIPQ (0) 
GTIIMTNYTAIFSNKEHWKHPDTFNPENFLDENGQFSKPKCFIAFGV (1) 
GPRICLGDTLAKTALFLFITSLLQRIRFSLPPDAKPMDMDGILSIIRYPETFSIICCSRDTKE* 

>NA54442 EXON 9 1 AA DIFF WITH 2AA2
235685 GPRICLGDTLAKTALFLFITSLLQRIRFSLPPDAKPMDMDGILSIIRYPETFCIICCSRDTK 235870

>CYP2AA3 BC055136 ctg14330 Zv3 05/2004 zfishC-a1177h12.q1c Z35723-a631b05.p1c
zfishI-a76h10.q1c
131529 MFTALLKLDLASVGLTLFLGLIILVLFEIFRIHSYKRRTPPGPTPLPFVGTIPHFLKNPLGFIR 131720
131812 MSQYGDMSTMYLGRKPAIFLNTIQLAKETLVQDTFSGKPYLPVIEWISKGFG 131967
132158 GIAMVTFNHSWRQQRRFALHTLKNFGLGKKSVEDRVLEESRYLIAEM
LKDEGKPVDPHHPIQNAVSNIICSIVFGDRFEYNNKRFEYLLKMLNETIMLAGSASGR
IFNLVPFIKHFPGPHQKIKKNTDDLLIFLGDEVEEHRKTLDPGSPRDFIDAYLLEIEK
QKFNKDSTFHEGNLLASAGDLFMAGTDTTETTIRWGLLLLIQNPDVQERCHEEIVRVL
GYDRLPSMNDRDRLPYTLATVHEIQRYGNIIPILIHETILPTKLQGYSIPQGTTIVTN
IQAIFSSKDHWKHPDTFNPENFLEDGHFIKPESFIMFSLGPRSCLGEMLARTELFLFI
TSLLQRIHFSWPPDAKPIDMDGIFGLVHSPQTFNVICRSRDTK

>CYP2AA4 ctg14330 77% to 2AA1 missing exons 1,2 dup exons 3,8
zfishB-a33e04.q1c zfishB-a46b05.q1c zfishC-a2901c10.p1c zfishK-a149h03.q1c
AI266900 (exons 1,2,3)
     MFGALVKLDLSSVGLTLLLGLILLVLFEIFRIHSYKSRFPPGPTPLPFVGNLPHLLRDPMGFNRL
     MAQYGEMSTMYLGKKPAIVLNTIQVAKEALVQEAFAGRPCLPVIDWTSNGC
 716 GIIMATFNNSWKQQRRFALHTLRNFGLGKKSIESRVLEESQYLFAELLKDE 868
1337 GKSMNPQHALQNAVSNIICSIVFGERFDYDNKRLGYLLKILNENMMLTGSAIGQ 1498
4286 IFNLAPFIKHFPGPHQKIKKNSNELYSFIEDEVEEHRKTLDPVSPRDFIDAYLLEIEK 4459
     QKSNKDSTFQEENLIGSAIDLFFAGTDSTATSIRWGLLFLIQNPDVQ 4684
5758 ERCHEEIVQVLGYDRLPCMDDCDRLPYTHATVHEIQRFAKTVPFGVFHETIWPTKLHGFDIPQ 5946
6575 GTMIMTNLAAIFSSKEHWKHPDTFNPENFLDENGHFSKPESYIPFSL 6715
8861 GLRACIGESLVRTELFLFATVLLQRIHFSWPPNAKPIDMDGIMGLVHSPQTFNVICRSRDTK 9046

>CYP2AA4-ie3 ctg14330 dup exon 3
1089 QRRFALHTLRNFGLGKKTVEDRVLEESQYLIAEMLKDEG

>CYP2AA4-ie8 ctg14330 dup exon 8
6375 GTMIMTNLAAIFSSKEHWKHPDTFNPENFLDENGHFSKPESY 6500

>CYP2AA.a ctg14330 exons 7,8,9 72% to 2AA1
55042 ERCHEEIVRVLGYDRLPCMDDRDRLPYTLATVHELQRCGNIVPSSVPHETTQPMKLRGYDIPQ 55230
55304 GTQMLINLSDILANKEHWKHPDTFNPENFLDDKGHFYRPEAFLPFSL
      GPRVCLGETLAKTELFLFITSLLQRIRFSWPTGEKWPNMDGIVSVVRSPEPFKIICHSRGSKE 55714

>CYP2AA.b ctg14330 exon 2 partial
59807 LSNIICSIVLGDRFSQDNIHFTYLFEVESHSGVVT 59911

>CYP2AA.c ctg14330 exons 1,2 only 1aa diff to AI658337
66316 MLAALLKLDLSSVGLSLFLGLIFLVLFEIFRIHSCKGRFPPGPTPLPFVGSIPHFLNNPMGFIKS 
      LSQYGEMTTVYPGRKPAIILNTLQLMK 66708

>CYP2AA.d ctg14330 exons 1-6 87% to CYP2 N-TERM COMPLETE
76460 XXXXXXKLDLSSVGLSLFLGLFCLALFEICRIRIYKGRYPPGPTPLPFVGTIPHFLKNPMGFIRS 76284
      LSQYGEMTTVYLGRKPAMVLNTLQVIKEAIVQNGTSSSGRPSIPILTWITEGY 76011
70340 GIVLATFGHSWRQQRRFALHTLRNFGLGKKSVEERVTEESGYLVPEMLKME 70188
69899 GKPFDPQHAIQNAVSNIICSIVFGDRFEYDNKRFEYLLEIIKENINQAGSLIGQ 69738
68815 VFNLIPIIKHFPGPHQKIYQNAEELKSFIRESTKSHRETLDPDSPRDFIDAYLLEMEK 68642
      QKSSQDSSFHEDNMVMSVADLFLAGSDTTATTIRWGLIYLTQNPDVQ 68238

>CYP2AA5 ctg14330 90% to 2AA2
77910 MFTALLKLDLAFVGLTLFLGLIFLVVFEISRIYSYKCRFPPGPTPLPFVGNLPHLLKKPMEFIRX 78101
78196 LSQYGEMTTMYLGRKPAIVLNTYQVAKEALVQEAFAGRPHLPIIEWITKGL 78348
78622 GIVMVTFNHSWKQQRRFAQHTLRNFGLGKKSLESRVLEESQYLIAEMLKDE 78774
78980 GRPMNPQHAVQNALSNIICSIVFGDRFDYNNKRFEYLLKILNESIILTGSAAGQ 79141
      IFNFAPIIKHFPGPHQMINENANEVYSFVRHEVEEHRKTLDPGSPRDFIDGYLLEMEK
81107 QKSNKDSTFHEDNLITTTVDLFLAGSDSTSSSIRWGLLFLIQNPDVQ 81249
85877 ERCHEEIVQVLGYDRLPCMDDRDRLPYTLATVHEIQRCGNIAPFGLFHETVQPTKLRGYNIPQ 86065
86197 GTIIMTNLAAILSDKEHWKHPDTFNPENFLDENGQFSKPKCFIAFGVG 86340
95083 PRSCLGETLAKTELFLFITSLLQRIRFSWLPDAKPLYMDGIMGIVRYPQPFIIICCSRDTK 95265

>CYP2AA.e ctg14330 exons 5,6,7 87% to 2AA1
100971 IYNLVPFIKHFPGPHQKIKQNADDLFNFIRDEAKEHKQTLDPDSPRDFIDAYLLEIEK 101144
101230 QKFNKDSTFHEEHLVVSTSDLFLAGTDTTETTIRWGLIYLIQNPDVQ 101370
103319 ERCHEEIVQVLGYDRLPSMDDRDKLPYTLATVHEIQRYGNIAPKLFHETIWPTKLHGFDIPQ 103504
103933 GTMIMTNLAAIFSSKEHWKHPDTFNPENFLDENGHFSKPESYIPFSL 104073

>CYP2AA.f ctg14330 exon 7 74% to 2AA1
       GTTIIANFTAMFSDKELWKHPDAFNPENFLDENGQFSKPEYFFPFSL 105159

>CYP2AA.g ctg14330 exon 2,3,4 89% to 2AA4
106599 LSEYGGLATVFIGRKPAISINTIQLAKEALVQDVFSGRPALPIFDWISHGL 106751
108240 GIIMVTFNHSWRQQRRFALHTLRNFGLGKKTVEDRVLEESQYLIAEMLKDE 108392
108527 GKSMNPQHALQNAVSNIICSIVFGERFDYDNKRLGYLLKILNENMMLTGSAIGQ 108688

>CYP2AA3 ctg14330 (7 aa diffs)
131529 MFTALLKLDLASVGLTLFLGLIILVLFEIFRIHSYKRRTPPGPTPLPFVGTIPHFLKNPLGFIRX 131720
131812 MSQYGDMSTMYLGRKPAIFLNTIQLAKETLVQDTFSGKPYLPVIEWISKGF 131964
132158 GIAMVTFNHSWRQQRRFALHTLKNFGLGKKSVEDRVLEXXXXXXXXXX 132271
133974 GKPVDPHHPIQNAVSNIICSIVFGDRFEYNNKRFEYLLKMLNETIMLAGSASGR 134135
136328 IFNLVPFIKHFPGPHQKIKKNTDDLLIFLGDEVEEHRKTLDPGSPRDFIDAYLLEIEK 136501
136597 QKFNKDSTFHEGNLLASAGDLFMAGTDTTETTIRWGLLFLIQNPDVQ 136739
       ERCHEEIVQVLGYDRLPSMDDRDRLPYTLATVHEIQRYGNIIPILIHETILPTKLQGYSIPQ 140163
143088 GTTIVTNIQAIFSSKDHWKHPDSFNPENFLEDRHFIKPESFIMFSL 143225
143308 GPRSCLGEILARTELFLFITSLLQRIHFSWPPDAKPIDMDGIFGLVHSPQAFNVICRSRDTK 143493

>CYP2AA6 NA16005 Exons 4-7, 9  fd54c03.y1 AW019538 = fd54c03.x1 AI658337 
fc21h01.y1 fc21h01.x1 CA473712 73% to 2AA1
      MLAALLKLDLSSVGLSLFLGLIFLVLFEIFRIHSCKGRFPPGPTPLPFVGSIPHFLNNPMGFIKS
      LSQYGEMTTVYPGRKPAIILNTLQLMKEALVQNGSSFSGRPPVPVFNWVTDGY
      GIVMATFGHSWRQQRRFALHTLRNFGLGKKSVEERVTEESGYLISEFLKAE
 4444 GKPFNPQHAIHNAAANIICSIVFGDRFDYDNKSFTYLLEIIKENIIQAGSLVGQ 4605 (0)
 7506 VFNLVPIIKHVPGPHQKIYQNGQAFKSFIRESVKEHRQTLDPDSPRDFIDAYLLEMEK 7679
 7891 QKSTQDSTFHEDNMVMAVGDLFLAGSDTTATTIRWGLIYLTQNPDVQ 8031
10145 ERCHEEIVRVLGFDRLPSMDDRDRLPYTLATVHEFQRCANLVPTGVPHETTQATKLRGYDIPQ 10334
10407 GTQILINLTEILTNKEHWKHPDTFNPENFLDDKGHFFKPEAFLPFSL 10547
      GPRACLGETLAKAELFLFVTSLLQRIRFSWPTGEKLPDMNGIFGIVRSPKPFNIICHSRGSKH* 10813

>CYP2AA6-ie6 NA16005 Duplicate exon 6 (3 aa diffs)
 9660 QKSTQDSTFHEDNMVMSVGDLFFAGTDTTATTIRWGLLYLTQNPDVQ 9800

>NA19331 SAME AS 2AA6 EXON 3
1605 GIVMATFGHSWRQQRRFALHTLRNFGLGKKSVEERVTEESGYLISEFLKAE 1757

>CYP2AA7 NA16005 Exons 1-7 83% to 2AA1 96% (6  diffs) to AI964243 EST269357 zfishG-a606c02.p1c
AI964243 probably = AI964242 and BQ605503 
17072 MFAALLKLDLASVGLTLFLGLIFLVLFEIFRINSYKGRFPPGPTPLPFVGNLPHSLKNPMEFIRS 17266
17365 MPQYGEMTTMYLGRRPAIVLNTIQLAKEAFVQDAFSGRPFLPVMDWVANGL 17517
17817 GIIMVTFNHSWRQQRRFALHTLRNFGLGKKSVEDRVLEESRYLIAEILKGE 17969
19246 GKPMSPHHPIQNAVSNIICSIVFGDRFDYDNKRFEYLLELLNENFVLTGSAAGQ 19407
19622 IFNLAPFIKHFPGPHQKIKQNANELLAFIQGEVKEHKKTLDPDSPRDFIDAYLLEIEK 19795
      QKSNKDSTFHEGNLAISTADLFLAGTDTTSTTIRWGLLFLTQNPDVQ 20038
20933 ERCHEEIVQVLGYDRLPSMDDRDKLPYTLATVHEIQRCANLVPFGVIHETIQPTKLRGYDIPQ 21121
      GTVVMTNLAAILSDKEHWKHPDTFNPENFLDENGHFSKPESFIPFSL
      GPRFCLGETLAKMELFLFITSLLQRIRFSSPPDAKPIDMDGIMGIVRYPQPFSIICCSRDTKE*

>NA1642 89% (11 AA DIFFS) WITH 2AA6
4748 GIIMAMDGHSWRQQRRFALHTLRNFGLGKKSVEERVTEESGYLISELLRVE 4596
3768 GKPFNPQHAIHNAAANIICSIVFGDRFDYDNKSFTYLLEIIKENLDLAGSFAGQ 3607

>CYP2AA8 NA3313 78% to 2AA7 zfishC-a402h10.p1c zfishC-a440h04.p1c
 540 MFSALLKLDLAFAGMTLILSLIFMFLLEIFRIHSFKSRFPPGPSPLPFVGNLPVFLKNPMEFIRS 734
 811 LSQYGEMTTIYLGRKPTIMLNTVQLAKEVLIQDAFAGKPSLPVLDWVSNGL 963
1198 GIVMVTFNHSWRQQRRFALHTLRNFGLGRKSVESRVLEESQYLIAELLKKK 1350
1544 GKSVNPHHALQNAFSNVICSIVFGDRFDYDDKRFEHFLEILGKSMILTGSTAGQ 1705
3903 IFNFAPIIKHFPGPHQKIKKNADELSGFFQHEVKEHKKTLDPGSPRDYIDAYLLEMEK 4076
     QKSNKDSTFHDENLIGSTTDLFVAGSDSTATTFRWGLLFLIQNPDVQ 4304
4703 ERCHKEIVQVLGYDRLPSMEDRDRLPYTLATVHEIQRCANLAPFGLIHETIQPTKLQGYDLPR 4891
     GTTIIVNLTAIFSNKENWKHPDTFNPENFLDESGQFSKHESFIPFSL 5173
8867 GVRVCLGETLARTELFLFITALLQRIRFSLPPDAKPMDMDGILSVLRYPQNFSFICCSRD 9046

>CYP2AA8 (may be new subfamily) AI964243 EST269357 zebrafish, 75% to 2AA1
KIKQNASELLAFIQGEVKEHRKTLDPDSPRDFIDAYLLEIEK
QQSNKDSTFHEGNLVISTADLFLAGTDTTSTTIRWGLLFLIQNPDVQ
ERCHEEIVQVLGYDRLPSMDDRDRLPYTLATVHEIQRCANLVPFGVIHETIQPTKLRGYDIPQ
GTVVMTNLAAILSDKEHWKHPDTFNPKNFLDENGHFSKPEVFIPFSL
GPXFCXGETLAKMELLLFITSLLQRIRXSSPPDAXPINLECLMGIIRYPXPFSIICCSRDTKE*

>NA54442 EXON 9 1 AA DIFF WITH 2AA2
235685 GPRICLGDTLAKTALFLFITSLLQRIRFSLPPDAKPMDMDGILSIIRYPETFCIICCSRDTK 235870

>NA1642 89% (11 AA DIFFS) WITH 2AA6
4748 GIIMAMDGHSWRQQRRFALHTLRNFGLGKKSVEERVTEESGYLISELLRVE 4596
3768 GKPFNPQHAIHNAAANIICSIVFGDRFDYDNKSFTYLLEIIKENLDLAGSFAGQ 3607



>CYP2.h ctg14330 exons 1,2 39% to 2N11
332047 VFSQLIGQWLDVQGFLIFLSVLLLVKHFRDVFTNNMPPGPFPLPFVGNVLSIGFGDPM 332220
339093 KYGDVCTFYIGTKPCILMTGYEVFKEAFVEQADIFTDRPFFPVNDRICKGKG 339248

>CYP2AD2 ctg24224.c AF248042, BC045948, NM_152954, AI497156 fb62g08.y1, AI545969 fb66e09.y1
zfishC-a1912g05.q1c
1188074 MILHLIYDSFDFKSWIIFFVVFLIIAEMIKNRTPSNYPPGPWPLPFLGTVFTKMDFKNINK 1187892
1186957 LAKVYGKVFSLRVGSEKMIIVSGYKMVKEALVTQNDSFVLRPPVPLFHKVYKGI 1186796
1186697 GLTMSNGYIWRSHRRFAASHLRTFGEGKKNLELGIQQECVYLCDAFKAEK 1186548
1186450 EPFNPIFILHGAVSNTVACLTFGQRFDYNDEWYQEILRLDNQCVQLAGSPRVQ 1186292
1184473 LYNAFPKLLDYLPGPHQKVFSNYKKITQSLKDEIIKHREDWDPANPRDFIDNYLTEMEK 1184297
1184224 KKSDPQAGFNIESLIISCLDIVEAGTETGATTLRWGLLFMIKFPEIQ 1184084
1183997 EKVQAEIDRVIGQSRQPCLDDRVNMPYTEAVLHEIQRFGDVVPLGFPKQAAVDTKIGNYFIPK 1183809
1183589 GTSITTNLSSVLHDPNEWETPDTFNPGHFLDKNGQFRKRDAFLPFSA 1183449
1181159 GKRACVGELLARNVLFLFFTSLLQQFTLSKCPGEEPSLEGEIWFTYAPAPFRISVSVR 1180986

>CYP2AD3 ctg24224.d Zv3 05/2004
1197538 MILQFIYENFDFKSWILLGFGLLLLVDLIKYWNPSSFPPGPRPLPFLGNVFTEIQDFRNINK 1197353
1197148 LAQVYGTIFSLRLGSEKLIIVSGYKMAKEALVTQNDSFIDRPNVPLFHKVFKGL 1196987
1196868 GTILSNGYLWRMHRKFAVSHLRNFGVGNESLEVKIQQECIFLCDAFKAEK 1196719
1196585 GPVDPMVTLNSAISNIISSLIFGQRFDYHDEYYQRILRLDTECIQLAGSPRAQ 1196427
1196323 LYNACPWLFEYLPGPHQTIFSNYKKIKDFLRGEIIKHREDWDPANPRDFIDNYLTEMER 1196147
1195690 KKSDPEAGFNIEGLVVTCLDLIEAGTETATTTLRWGLLFMIKFPEIQ 1195550
1195375 EKVQAEIDRVIGQSRQPCLNDRVNMPYTEAVIHEIQRFGDVVPLGFPKRAVKDTQLGKYFIPK 1195187
1195107 GTAITVNLSSVLHDPNEWETPDTFNPGHFLDEIGQFRKRDAFMPFSA 1194967
1194856 GKRACLGENLARQELFLYFTSLLQQFKISKCPGEEPSLEGEIWFTYAPAPFHICVSSR 1194683

>CYP2AD6 ctg24224.b 54% to 2AD3 zfishC-a250a11.q1c (100%) zfishG-a1026b07.q1c (4 aa diffs)
1179581 MILYSLYDCLDFKGWLFLTCFLLLLIDLIRNKNPANFPPGPWPLPILGNVFTDVNYKTVDQ 1179399
1178673 LIEKYGNIFSVRIGSDKIVYVSGFKMVKDVLITQGENFTDRPVSPLFDTLYKGR 1178512
1177003 GLSFNNGYSWRKHQQFSMSHLKNFGEGRKTLEENNQRECYFLCGAFKEEQ 1176854
1176222 GRPFDPLVKINNAVANVIGFLVFGHRYEYSDVNFQKRLQMSAESVFLTGSVWNQ 1176073
1174591 LYDAFPGIMKWVPGPHQTIISNYQKLANFLEEKIEQHKPDWDISNPRDYIDAYLTEAEK 1174415
1174323 KKNDTEAGFTVGSLVWSMVDLFEGGTETTTNTLRWALLFLIKYPDIQ ()
        EKVQAEIDEVIGSRLPSMSDKANMHYLNAFIHEVLRRANLVPLNMARVAKKDTTLGGYFITK 1173862
1172788 GTVMITNLTSVLYDKQEWETPDAFNPKHFLDSEGHFCRRNAFFAFSA 1172648
1172050 GKRQCPGEYLAHLELFIFLTILLQTFSFSPPDGEEPSLDSQVGFTQAPLPYKICAHPR 1171877

>CYP2AE1 NA7219 zfishG-a147a09.q1c zfishG-a1551g08.q1c Z35723-a848d07.q1c 
49% to 2P6 48% to 2N13 46% to 2V1 46% to 2AD2
28876 MSSVFSQLIGQWLDVQGFLIFLCVLLLVKHFRDVYSKNMPPGPFPLPFVGNLTNIGFSDP 28715
28714 LGSFQR 28697 (0)
28473 IAEKYGDVCTLYLGTKPCILMTGYDTLKEAFVEQADIFTDRPYFPIVDKLGN 28336 (1?)
26270 AGLIMSSGHMWRQQRRFALATLKYFGVGKKTLENAILQECRFLCDSLQAER 26118
25139 GLPFDPQHLVTNAVSNIICGLVFGHRFEYDDHQFHLMQTYINNILQLPISNWGR 24978
24700 LYNEFPTLMSLLPGKHQTAFASMSKLQPFLKEEITKHQQDREPSSPRDYIDCYLEEIEK 24524
21648 QCKDSDAEFTEENLMFCVVDLFGAGTETTSNTLRWALAFMVKYPDVQ 21508
21386 EKVQSEIDQVIGQTRQPLMDDRTNLPYTYAVIHEIQRFANIVTFTPPRVANKDTTVGGQLIPK 21198
18506 GVIVLPMLKPILLDKKEYSTPYDFNPDHFLDQNGKFLKKENFIPFSI 18366
14291 GKRMCPGEQLAGMELFLFFISLMQHFTFLPPEGETLSLKIFLAIASAPAPFRI 14133
      KAVPRQCDNTAS*

>CYP2AE1-de9 extra exon 9
8074 GKRMCPGEQLARMELFLFFISLMQHFTFLPVEGQKLSLKGTTSVSSAPQPFQI 7916

>NA3366 70% to 2AE1 exon 5
LYNAFPSVMPLLPGKHQTAFANLTKLKLFFQEEINKHKENRNPYSPRDYIDCYLEEIEK

>NA6181 CYP2AE exons 7,8 fragment 75% to CYP2AE1 Z35723-a2390a11.q1c
1264 EKVHTEIDQVIGQSRQPLMEDRAHLPYTYAVMHEVQRFANVLAFIPPRVASKDTTVAGFLIPK 1452
5048 GVMVLPMLKPILEDKNEYCTPNEFNPAHFLDE 5143

>CYP3A65 ESTs CF266016 CF999879 CF996069 CD014436 Zv3 NA14528, NA1203, NA25592
      MFFSAETWTLLAFLVALLVI
 8456 YGSWPHRYFKKLGIPGPKTIPFFGTMLRYKD 8548
 8713 GFHVFDMDCFEKYGRIWG 8766
 8867 IYDGRQPVLCIMDQTIIKTVLIKECYSLFTNRR 8965
 9039 NFRLNGALYDAVSIAEDDDWRRIRSVLSPSFTSGRLKE 9152
 9576 MFGIMKKHSHILVDSMGKTAKRGESADIKE 9665
12156 FFGAYSMDVVTSTAFSVDIDSLNNPKDPFVTNIKKMLKFDLLNPLFLLI 12302
AFFPFMAPVLEKMDFALFPTSVTDFFYAALQKIKSDRDTKTVAKDNTK
KRVDFLQLMVDSQTGVKHKSDGETHEK
GLSDHEILSQSMIFIFAGYETSSSTLSFLFYNLATNPETMKKLQEEIDETFPNQAPVD
YETLMSMDYLDAALSESLRLYPVAARLERVCKKTVEING
LLIPKDLVVMVPTYVLHRDPDYWSEPESFKPER
68  YETMMSMDYLDAALSESLRLYPVAARLERVCKKTVEING
    LLIPKDLVVMVPTYALHRDPDYWSEPESFKPER 283
630 FTKGNKESIDPYMYMPFGLGPRNCIGMRFAQVTMKLAIVEILQRFDVSVCDETQ 791
437 VPLELGFNGLLSPKDPIKLKLQPRKLSQSPDVCNNNQKS* 556

>NA13936 
          Length = 26946

Possible CYP3-like exon 1
Query: 1    MFFSAETWTLLAFLVALLVI 20
            MFFSA+TW + A    LL +
Sbjct: 7301 MFFSAKTWQIQAIATHLLKV 7360

>ctg14568 
          Length = 383278

Possible CYP3-like exon 3
Query: 3      HVFDMDCFEKYGRIWG 18
              H+ + D F KYG  WG
Sbjct: 204294 HLVEADTFRKYGICWG 204247

>ctg11102 
          Length = 1220461

Possible CYP3-like exon 4
Query: 13     DQTIIKTVLIKECYSL 28
              D+ +IKTV+IKE YSL
Sbjct: 259498 DRAMIKTVIIKELYSL 259451


>CYP3B1 fugu Scaffold_2213a 3A-like Length = 32737 one of two genes 13 exons
6382   MFEFVLFSGTTWALLALFFALLLL 6311 (2)
6232   YGVWPYHHFKKLGIRGPRPLPFMGSTFYYRK 6134 (0)
6052   GIIPFESWCQAEYGDVWG 5999 (2)
       MFEGRTPVLMVSDPEILKTVLVKECYSVFTNRR (0)
5469   DSFAGPLEDSVSAVKDERWKRIRSTISPCFTSGRLKN 5368 (0)
5259   AFPIVARYADRITKKLEQSNLDEPINVKE 5173 (2)
5069   FLAPYSLDAVTSVSFSVEADSINNPNDPLIVNLKKVFKFNFVVFFLV 4929 (1)
4846   AFFPFCARLFQFLGIDPIPRSSVNYFYNVIKNFKDQHHAD 4727 (bad boundary, 0 expected)
4124   TRGDFLQVLIQSEIPQSEIKSEQDQPPK 4041 (1)
4011   GLTEHEILSQAFIFIFGGYETTTTTLTNVLYGLAINPDVLQVLHKEIDTNIPSD 3850 (0)
3780   APISYEDLMGLQYLDQVLNESQRLYPTAPRLERACKKTVQIHG 3652
3651   LTILEGTIVGIPVHLLHKDPRFWSSPEEFRPER 3553 (2)
3416   FSKDSTEEVNPYAFMPFGLGPRNCVGMRYAILVMKMLIVRLLQSYTVETCKDTM 3252 (0)
3171   IPLEFDWKSQPLKPIKLSFIPRQK* 3097

>CYP3C1 NM_212673 AW076890 fj03b10.y1, BF717373 fd45a03.y1 
MFDLSSLSVTWTLVVLVITLLLI
YGVWPHGFFKKLGIPGPRPLPFVGTALSYSK
GICNFDIECSKKYGKVWGIYDGRLPLLLVTDLEMIKTILVKDCYSTFT
NRRNMNPDLVGPFADGITLVKDERWRRIRSSLSPYFTSGRLKEIFPIAMTHADRFIKN
MEKKDPNLPLKIKDVVAPYSLDVVASSSFSVDFDSINNPDDPFVTSIKSFFNINPLSP
LFLLLAFCPSAANLLAKMGISVFSRSTTDFYYKALRKIKDEHNESNGRVDFLKLMIQN
QIPDDQVKDTASEQPVKGLTDHEILSQSFIFILGGYETTSTTLSYLLYNLATNPDCLE
KLVEEIDKNFPLDIPITYDALMRMDYLEMAIHESMRVFPAGPRLERVCKKTVEINGIT
IPKNTLVGIPLYVLSRDPDLWESPNEFKPERFSPESKTEINQCAFMPFGLGPRNCIGM
RFALMMMKLLVVKLLQKYTVETCKETQIPVQLNFFFQPKVPITLKLIPRSHKEKQ

>CYP3C1 = ctg14194.a BC052130 51% to 3B2 fugu
962455 MFDLSSLSVTWTLVVLVITLLLI 962523
       YGVWPHGFFKKLGIPGPRPLPFVGTALSYSK 962748
962849 GICNFDIECSKKYGKVWG 962902
963211 IYDGRLPLLLVTDLEMIKTILVKDCYSTFTNRR 963390
       NMNPDLVGPFADGITLVKDERWRRIRSSLSPYFTSGRLKE 963534
963811 IFPIAMTHADRFIENMEKKDPNLPLKIKEY 963990
963994 VAPYSLDVVASSSFSVDFDSINNPDDPFVTSIKSFFNIN 964131 PLSPLFLLL
964899 AFCPSAANLLAKMGISLFSRSTTDFYYKALRKIKDEHNESN 965021
965132 GRVDFLKLMIQNQIPDDQVKDTASEQPVK
965334 GLTDHEILSQSFIFILGGYETTSTTLSYLLYNLATNPDCLEKLVEEIDKNFPLDX 965495
968502 PITYDALMRMDYLEMAIHESMRVFPAGPRLERVCKKTVEINGITIPKNTLVGIPLYVLSR 968681
968682 DPDLWESPNEFKPER 968726
968806 FSPESKTEINQCAFMPFGLGPRNCIGMRFALMMMKLLVVKLLQKYTVETCKETQ 968967
       IPVQLNFFFQPKVPITLKLIPRSHKEKQ*

>CYP3C.b ctg14194 51% to 3A48 50% to 3B2 75% to 3C1
973107 MIDLSSLSVTWILVVLVLTLLXX 973169
973400 YGVWPHGFFKKLGIPGPRPWPFFGTFLSYTK 973492
973615 GFFNFDMECAKKYGKVWG 973668
973846 IYDGRLPILMVTDLEMIKTIMVKECYSTFTNRR 973944
974123 EINVDLAGPLADGITAVKDERWKRIRGTLSPYFTSGRLKe 974239
975373 IFPIAMTHADRFIKNMQRGTTNSQLKSKXX 975456
975627 MASYSLDVVTSSAFSVDIDSINNPDDPFVTNIKNFLKFN
       AVFPSIANLLGKMGLSMFSKPTVDFFYKALRKIKEEHKDSN 975986
       GRVDFFRLMIQNEIPDDQVKDTTSEQPEK
976291 GLTDHEILSQSFIFIMGGYETTSTTLTFLLYNLAINPDCLEKLVEKIDKNFPLDX 976452
978970 PISYDALMKIDYLEMSINESMRLLPTAPRLERVCKKTVEMNGITIPKDTMITIPTYVLNQ 979149
979150 DPQLWDSPHEFRPER
       FSPENKSEFLQYAFMPFGLGPRNCIGMRYALMIVKLLVVKLLQNFSVETCKETQ 979530
       IPLELNPVFQPKVPITLKLTPRKRXXXX 979689

>CYP3C.c ctg14194 75% to 3C1
985170 MIDLSSLSVTWTLVFLVITLLXX 985232
985463 YGVWPHGFFKKLGIPGPRPWPFFGTFLSYTK
985681 GFFNFDMECAKKYGKVWG 985734
986759 IYDGRLPILMVTDLEMIKTIMVKECYSTFTNRR
       EVNVDLAGPLADGISAVKDERWKRIRGTLSPYFTSGRLK 987097
988325 IFPIAMTHADRFIKNMQKRDHEQPVKIKEY 988414
       VAPYSLDVVTSSSFSVDIDSINNPDDPFVTNIKNFLKFS 988744
988875 ALFPSIANLLGKMGISVFSRSIMNFFYTALRKIKDEHKDSN
989268 XRVDFLRLMIQNQIPDDQAKDTTSEQPVK
989460 GLTDHEILSQSFIFIPGRL*DNKHDSLFPPHNLATNPDCLEKLVEEIDKNFPLDX 989621
989770 PISYDALMKMDYLEMSINESMRLLPTAPRLERVCKKTVELNGITIPKDTLVAIPTYVLNR 989949
989950 DPQLWDSPQEFRPER
       FSPENK 990129
990130 SEFLQYAFMPFGLGPRNCIGMRFALMIVKLLVVKLLQNFSLETCKETQ
       IPLELTPVFQPKVPITLKLTPRKR 990420

>CYP3C.d ctg14194 exons 2,3 and 11-13
995697 YGVWPHRFFIKLGIPGPRPWPFVGTLLSYAK 995789
995861 GLCNFDMECAKKYGKVWG 995914
997604 PITYDALMRMDYLEMAINESMRLLPTAPRLERSAKKTVVINGLTIPEGTLVGIPTYVLSH 997783
997784 DPDIWESPGEFRPER 997828
998204 FSPENKSEFLQYAFIPFGLGPRNCIGMRYAVMIMKLFVVKLLQNFSVETCKETQ 998365
998446 IPLEINVTFQPKVPITLKLIPR 998511

>CYP3C.e ctg14194 70% to 3C1 exons 4-10
1012478 IKVVLVKECYSNFINRR
1012658 GPFSDGIIMVKDERWKRMRSTLSPYFTSGRLR
1012857 IFPIAMTHADRFIKNMQKKDPEQPVKIKEY 1012946
1013136 VAPYSLDVITSSSFSVDIDSINNPEDPFVINVKKFIQFN
        VLFPSLAIPLKKMGVTLFSKSAMDFFYSVLKKIKDDHNKEXX 1013478
1013564 XRVDFLKLMLQNQIPDDQIQDSDTSEQPAKGL
1013759 GLTDHEILSQSLVFILGGYETTSTTLTFLLYNLATNPDCLEKLVEEIDKNFPLDV 1013923

>CYP4F43 BG799227 (exons 1-4) NA16252 (exon 2) NA2909 (exons 3-12) ctg12233 (exon 13) CD593651 (exons 4-6)
      MMLFGLSVTGILALSGAALLCALVTRIIINRRALRCFNQPPLRNWIMGHMGL ()
  640 MGHNEEGLQRVDDLVCKYGHSCSWFLGPFYNMVRLFHPDYIRSLLTAS 497 ()
  396 ASITLKDRIFYGFMKPWL 449 ()
 3445 GNCLLLQSGQEWSRHRRLLTPAFHFDILKKYVHIFNQSTNIMH 3573 ()
      DEWRRLLASGEHSVDMFEQISSLTLDSLLKCTFSCDTHSQE ()
 7353 KPRQYISAILDLSRLLVQRQHYLPYHWD 7436 
 7438 WLYWRSAQGRRFQQACAVVHQFTADIVQERRTQLDQQSDPESHPENTGRYRKRKNTDLIDLLLLAK 7635 ()
 9210 DDKGEALTNEEIKAHADMFMFA 9275 ()
10101 GHDTTASALSWIFYNLAMNQDYQERCRAEVRDLLADRDTHTIGW ()
      EDLSQLTFTTMCIKESLRLHSPVLALTRYYSQNMKTPGDCVIPH 10508 ()
11457 GCLCLISIYGVHRNPQVWPDPL 11522 ()
14416 VFDPTRFDPHNSDSRSPHAFIPFSAGPR 14499 ()
87453 NCIGQNFAMAEMKVVVALTLARFKILPGPKPVRRLYQLVLRAEGGMILHFQELNEE* 87623

>CYP4T BC056734, NM_199216, CF943677 64% to 4T5 AI959112 fd24f08.y1 AI558878 fb67e05.y1
MLLYGISPFVLSVNHVFALIFLACLLTVVKLLIVRRKGVKTMER
FPGPPAHWLFGHVKEFRQDGHDLEKIVKWMELYQFAFPLWFGPSLAVLNIHHPSYAKT
ILTTTEPKDDYAYKFFIPWLGDGLLVSTGQKWFRHRRLLTPGFHYDVLKPYVKLISDS
TKVMLDKWEVHSRSEESFELFKHVSLMTLDSIMKCAFSCNSNCQTDSGTNPYIQAVFD
LCHLVNLRFRVFPYHSKAIFHLSPHGYRFRKAASIAHNHTAEVIRKRKEVLKMEEEQG
IVKNRRYLDFLDILLSARDEHQQGLSDEDIRAEVDTFMFEGHDTTASGISWIFYNLAC
NPEHQEKCRQEIQQALDGKDTLEWEDLNKIPYTTMCIKESLRLHPPVPGISRKLTKPL
TFFDGRTVPEGCTIGVSIYGIHMNSTVWENPYKFDPLRFLPENAANRSPHAFVPFSAG
PRFVTRSV

>CYP4V6 ctg26375 Length = 1844770 zfishC-a2539b10.q1c 71% to 4V5
376568 MVAFVGVYTYGFVAASVCVICFAYITYQLLKSYLHKWKELKPIPGIGNTFPFIGNALQFKSNGG 376759
377187 DFFLQLVGYTTEFQNSPLLKIWIGPIPFLILFHAETVE 
377942 TVLNNPVHIDKAYAYQFLHPWLGTGLLT 378025
379013 STGDKWRRRRKMLTPTFHFSILTEFLEVMNEQAEVLIEKLEKQAGKGPFNCFSHITLCALDIIC 379204
379875 ETAMGKRIYAQSNYDSEYVRTVYR 379946
       MSDIITRRQRMPWYWPDFVYNYVGEGREHNRSLKILHSFTES 382682
       VINERAEYLSYVESDSESDQGMRKRRAFLDMLLKTKDEDGKMLTHKDIQEEVDTFMFE 382937
385359 GHDTTAAAMNWAIHLLGSHPEVQRKAQQELFEVF 385460
386723 GESERPVNTEDLKKLRYLECVIKESLRLFPSVPFFARTICDDTQI 386857
387366 DGFKVPKGTNIVVITYALHRDPRFFPDPEEFRPERFLPENCVGRHPYAYIPFSAGLRNCI 387545
387722 GQRFAIMEEKVILAYILRYFNIVACQKREELRPLGELVLRPEQGIWITLERRKLTMS* 387895

>CYP4V7 ctg12974 69% to CYP4V 70% to 4V5 fugu, 70% to 4V6
396649 MGILFGLYILGILFTAVLLLLLASTAYNPLKNYIGKWNEMRPIPGMAGAYPIIGNALQFKTNAG 396840
396911 DFFNQIIEGTNENRHLPLAKVWVGPVPFLILYHAENIE 
397137 VVLSNSRHLDKSYSYRFLHPWLGTGLLT 397220
401404 STGEKWRNRRKMLTPTFHFSILSDFLEVMNEQTDILIQKMQKLEDGEPFNCFNFITLCALDIIC 401595
403742 ETAMGKKIYAQSNADSEYVQSVYK 403813
       MSDIITKRQRAPWLWPDWIYNKLKEGKEHAKRLKILHSFTAN 404756
406243 VIRERAEFMSSEPDSDSDQGGRKRQAFLDMLLKTTYENGQKLSHEDIQEEVDTFMFE 406413
406516 GHDTTAASMNWALHLIGSHPEVQKAVQAELQEVF 406617
410614 GSSERHVGVEDLKKLRYLECVIKESLRIFPSVPLFARSICEACHI 410748
411158 DGFKVPKGVNAVIIPYALHRDPRYFPEPEEFQPERFMPENSKGRHPYAYIPFSAGPRNCI 411337
413219 GQRFAMMEEKVVLATILRHFDVEACQSREELRPLGELILRPEKGIWIKLQRRSK* 413383

>CYP4V7-ie6 ctg12974 duplicate exon 6
398649 MSDIITKRQRAPWLWPDWIYNKLKEGKEHAKRLKILHSFTAN 398512

>CYP5A AY398422 BG728082 BF718045 AW595283
MQLLVDGLKWFGVEASGLSLTVCLFLLFLSLLYWYSISPFSNLE
RCGIKHPKPLPFIGNLMMFRNGFFKSQADLINKYGRICGYYIGRRSTVIIADPDMLRQ
VMVKEFNKFPNRMTARGITKPMSDSLIMLKGEQWKRVRSILTPTFSAAKMKEMVPLIN
TATETLLRNLKSHAESENSFNIHKCFGCFTMDVIASVAFGTQVDSQNNPDDPFVHQAS
KFFAFSFFRPIMIFFMAFPFLLRPLAGLLPNKSRDEMNSFFTQCIQKMIKQRDDLSPE
QRRKDFLQLMLDVRTNNKFLSVEHFDVVNDADEEAYDGHENSPANESTKRSQQKRMMT
EDEIVGQSFIFLVAGYETSSNTLAFTCYLLAVHPECQKKLQEEVDEFFSRHEMVDYAN
VQELKYLDMVICESLRLYPPAFRVARDVEEDTVLNGQFLPKGASLEIPTGFLHYDPEH
WTEPTKFIPERFTPEAKARRHPFVYLPFGAGPRSCVGMRLAQLEIKVALVHIFRRFNV
LACEDTEIPLELKSHTTLGPKNGVMVKITERENLEDAS

>CYP7A BC054571 BF718169 fd57d07.y1 BF717505 fd45f11.y1
MILTISFIWAIVVGLCCCLWLITGIRRRHPAEPPLENGWIPFLG
CALQFGANPLEFLRSRQKKHGHIFTCKIAGQYVHFLCDPFSYHAVIRQGRHLDWKKFH
FDASAKAFGHESMDPSQGYTTENLHQTFLKTLQGDALSSLIETMMENLQGTMLQSGML
KATTSEWQSDGIYAFCYKVMFEAGYLTLFGKELDGDQSIARQQAQKALVLNALDNFKE
FDKIFPALIAGLPIHVFKSAYSAREKLAKTMLHENLSRRANVSDLISLRMLLNDTLST
FNELSKARTHVAILWASQANTLPATFWTLFHMIRCPAAMKAASEEVRQTFESSNQKVD
PTNSRLVLTREQLDNMPVLDSIIKEAMRLSSASLNVRMAKSDFLLQLDNKESYHIRKD
DVIAMYPPMIHFDPEIYDDPLEFKYDRYIDEKGQEKTAFYRNGRKLRYYYMPFGSGVT
KCPGRFFAVHEIKQFLSLLLSYFEMELLDSDVKEPPLDQSRAGLGVLQPTYDVDFRYR
LKSL

>CYP7C 51% TO 71C1 FUGU ctg22254 BI473289 fp42a01.y3
1293024 MLEYLLTILLGFISVLLLYSFCGRRR 1292947 ()
1287477 KDGEPPLIKGWIPFLGKALEFRKNSQEFLTRLQKEHGDDFTVL 1287349
1285501 CVSLGRYITFIMNPLQYPSVIKHGKQLDFHTFSDSAASRTFDYPPIRSGHFPGLSDQIQR 1285322
1285321 SYTLLQGPALDPLTFSMMGNLQKVLRQLFLSGDEADDHWQQAELYKFCKSAMFQSTFKT 1285145
1285144 LYGHSPHLDLDQLREDFEKFDDMFPLLMARIPIGLLGKTKEIREKLIHFFYPQRMM 1284977
1284976 EWTAPCEFVQTRTALFQDYDTLQDRDKA 1284893
1282125 AHHFAMLWASVGNTIPAALWCLYHLISCLEALAAVREEITNVLGEKNMQLIFKEDIAITR 1281946
1281945 QQLEQMVYL
1279040 ESSVNESLRLYSVSMNIRVVQEDFCLRLDGQRSINMRKDDIIALYPQSTHLDPEIYKEPK 1278843
1276935 FQFDRFVKDGKEKTDFYKSGQKVRYYRMPFGSGATQCPGRFFAMNELKQFVCVTLLMCEM 1276756
1276755 QLLDGQQEASMDNSRAGLGILPPANPIPFKYKTR 1276654

>CYP7D1 BG883457 fp29f09.x1 381-502 54% to 7A
Z35725-a6349d05.p1c zfish44907-2306b01.p1k Z35723-a1126c05.p1c
ctg24516 BG884003 fp29f09.y1, 
233574 MLIITVFVCRKPGEPPLVTGWLPFIGVTKDYVSNPLGFLTETQKKHGNVFTCLIAGKYFTFV 233759
233760 TDPFSFSSVVRQGKNLDFQKFAINFSQR 233843 ()
240697 VFGHADFNSPQLSGNYREIHSIFRQTLQGPSLQHLTQSMLCNLQTVLERCLPHEH 240861
240862 DWLEEGVQSFTNRIMFEAGFLTLFGKEDIRFLQDHGMSGNRISMPKATQDFLVFDHAFPL 241041
241042 LAAGVPIGLCTKAWRAREALAEELLHDELHRRKCISDLIQRRMDIFDRMLLDETGKART 241218
241219 DVCMLWASQANTLPAAFWSLYYTLK 241293 (2)
242645 SVDAFTAARTEVNRVLLGQSLNNKDQTVYLSKDQLDSMTVL 242767 ()
244966 ESIIEEALRLSSASMMIRVASDDFTLTLESDQTAAIRKGDYIALYPQLLHLDPEIYPNPT 245145 ()
247157 EFKYNRFLDENDQPKTNFFKSGRRLRNFLMPFGSG 247261
247262 ASECPGRFFAVYEIKLFLALTLWHYDLQLRDPDVPVVQDSARAGLGIMPPSQDVLLRFR 247438
247439 KKQRTPGNEHKDTK* 247483

>CYP7D CATFISH CB936535 IpCGJx13_4_E02_23 IpCGJx13 Ictalurus punctatus cDNA clone 73% to 7D1
RQLESMTVLESIIKEALRLSSASIMIRVASDDFILTLDSGQQAAIRKGDYIALYPRLIHL
DPDIYPNPLEFKYDRFLDEEGQRQSQFFKNGRQLKHYLVPFGSGASECPGRFFAMNEIKQ
FLLLALWHYDLQLSEPHDTLSPDRTRAGLGILPPSQDVLLRYRARADRYTERAWGENDAD
DD*

>CYP8B.a ctg10820 68% to 8B1 fugu (no introns) 90% to CYP8B.c 91% to CYP8B.b
AI558624 fb68e08.y1
123025 XXALVQILLALLISVIGALYLLGSFRRRRTGEPPLEKGPIPWLGHVLEFRKDTAKFLNRMKA 122846
122845 KHGDIFTVQLGGFYFTFITDPLSFGAVVKEARAKLDFTKFAEQLVQRVFGYHSIQSEHKV 122666
122665 LQASSTKHLMGDGLVVMTQAMMYNLQNLMLHSVGSGNGKVWQESGLFAYSYNIVFRAGY 122489
122488 LSLFGNESPKGTGKESVEKAKEIDRQESNDLFWEFRKYDQLFPNLAYGVLGPSEKMEAER 122309
122308 LKRLFWSTLSVQKMRARDNISGWVSDQQQVRAEHGMQEFMQDRYMFLLLWASQGNTGPSA 122129
122128 FWLLLYLMKHPEAMSAVRKEVEEILKEAGQEVKPGGPLIDLSRDMLLKTPILDSAVEETL 121949
121948 RLTAAPILTRAVMQDMTIIMANGQEYKIREGDRVAVFPYVVHVDPEVHPDPLTFKYDRF 121772
121771 LNADGSRKTDFYKGGKKLKYYSMPWGAGTTMCPGRFFATNELKQFVFLMLSYFDFELTNP 121592
121591 NEQIPGIDIRRWGFGSMQPDRDIQFRYRPR 121502

>CYP8B.b ctg10820 66% to 8B1 fugu (no introns) missing N-term 41aa 93% to CYP8B.c
140828 WLGCVLEFRKDTVKFLQRMKAKHGDIFTVQLGGFYFTFITDPQSFGAVVKESRAKLDFTN 141007
141008 FADQLVERVFGYGAVEIKHKFFKNLQTTSTKHLMGDGLVVMTQAMMYNLQNLMLHSVGSG 141187
141188 NGKVWQESGLFAYSYNIVFRAGYLSLFGNESPKGTGKESVEKAKEIDLQHSNDLFWEFR 141364
141365 KYDQLFPNLAYGVLGPRGKMEAERLKRLFWNMLSVQKMKARDNVSGWVSDQQQVRAEHGM 141544
141545 QEFMQDRFMFLLLWASQGNTGPSAFWLLLYLMKHPEAMSAVRKEVEEILKEAGQEVKPGG 141724
141725 PLIDLSRDMLLKTPILDSAVEETLRLTTAPLLTRGVMEDMTIIMANGQEYKIREGDRVSV 141904
141905 FPYLVHIDPEVHPDPLTFKYDRFLNADGSRKTDFYKDGKKLKYYSMPWGAGTTMCPGRF 142081
142082 FATNELKQFVFLMLSYFDLELKNPNEEIPSIETRRWGFGSMHPDRDIQFRYRPR 142243

>CYP8B.c ctg10820 66% to 8B1 fugu (no introns)
154751 MESLVQILLALLLSVIGALYLLGGFRRRRTGEPPLEKGLIPWLGCVLEFRKDTVKFLQKM 154930
154931 KAKHGDIFTVQLGGFYFTFITDPLSFGAVVKESRAKLDFTKFSDQLVERVFGYHPMENEH 155110
155111 KFLQTASTKHLMGDGLVVMTQAMMYNLQNLMLHSVGSGNGKVWQESGLFAYCYNIVFRA 155287
155288 GYLSLFGNESPKGTGKESVEKAKEIDLQHSNDLFCEFRKYDQLFPNLAYGVLGPRGKMEA 155467
155468 ERLKRLFWSTLSVQKMRVKDNISGWISDQQQVRAELDMQEFMQDRFMFLLLWASQGNTGP 155647
155648 SAFWLLLYLMKHPEAMSAVRKEVEEILKEAGQEVKPGGPLIDLSRDMLLKTPILDSAVEE 155827
155828 TLRLTTVPLLTRGVVQDMTIIMANGQEYKIREGDRVSVFPYLVHIDPEVHPDPLTFKYD 156004
156005 RFLNADGSRKTDFYKDGKKLKYYSMPWGAGTTMCPGRFFATNELKQFVFLMLSYFDFELT 156184
156185 NPNEQIPDIDIRRWGFGSMHPDRDIQFRYRPR 156280

>CYP8A like BE558156 169-391
 11 YSLLFKTGYLTVFGA*NNDSAPLTQIYEEFRRFDKLLPKLARTTINNEEKQ 163
164 IASAAREKLWKWLTPSGLYRKPREQSWLGSYVKQLQDEGIDAEMQRRAMLLQLWVTQGNA 343
344 RPAAFWVMGYLLTHPEALRAVREEIQGGKHLRLEERQKNTPVFDSVLWET 493
494 LRLTAAALITXDVTHDKKIRLSYGQEYHLRLGDQLCVFLFISP 622

>CYP8A ctg11735 ESTs BE605271 BE558055 BE605774 HTGS seq BX649305.2 exon 3
47% to 8A1 human 56% to 8A1 fugu
279412 MMWTALLLVGLSILVIVLYGRRTR ()
279598 RRNEPPLDKGMIPWLGHALEFGKDAAKFLTRMKEKHGDIFT 279720 (0?)
       VRAAGLYITVLLDSNCYDAVLSDVASLDQTSYAQVLMKRIFNMILPSHNPESEKKRAEM
283569 HFQGASLTQLSNSMQNNLRLLMTPSEMGLKTSEWKKDGLFNLCYSLLFK 283715
       TGYLTVFGAENNDSAALTQIYEEFRRFDKLLPKLARTTINK 286445
286568 EEKQIASAAREKLWKWLTPSGLDRKPREQSWLGSYVKQLQDEGIDAEMQRRAMLLQLWVTQ 286747
292253 GNAGPAAFWVMGYLLTHPEALRAVREEIQGGKHLRLEERQKNTPVF () 22390
293226 DSVLWETLRLTAAALITRDVTQDKKIRLSNGQEYHLRRGDRLCVFPFISPQMDPQIHQQPE 293408 (0)
297049 MFQFDRFLNADRTEKKDFFKNGARVKYPSVPWGTEDNLCPGRHFAVHAIKE 297201 ()
299667 LVFTILTRFDVELCDKNATVPLVDPSRYGFGILQPAGDLEIRYRIRF* 299810

>CA374551.1 649002 NCCCWA 1RT Oncorhynchus mykiss cDNA CYP8A1
43  MLWTIFLLLNGLLALVILYSSRSRQKNEPPLDKGFIPWLGHALEFGKDAAKFLTRMKQKHGDI 231
232 FTVRVCGRYITVLLDPNSYDAVLDDKVSLDFSRYAQVLMQRIFNLRLPNHNPETERAWME 411
412 QHFQGPSLARLSSTMHLHLQTLLRDEERRCSPADWRQDGLFSLCYSLLF 558
    GAGYLTLFGAENSNDVTALATVYKEFRTFD

>CYP11A1 BC054701
MARWNVTFARLDQSLSSLKNLLQVKVTRSGRAPQNSTVQPFNKI
PGRWRNSLLSVLAFTKMGGLRNVHRIMVHNFKTFGPIYREKVGIYDSVYIIKPEDGAI
LFKAEGHHPNRINVDAWTAYRDYRNQKYGVLLKEGKAWKTDRMILNKELLLPKLQGTF
VPLLEEVGQDFVARVNKQIERSGQKQWTTDLTHDLFKFSLESVSAVLYGERLGLLLDN
IDPEFQHFIDCVSVMFKTTSPMLYLPPGLLRSIGSNIWKNHVEAWDGIFNQADRYIQN
IFKQWKENPEGNGKYPGVLAILLMQDKLSIEDIKASVTELMAGGVDSVTFTLLWTLYE
LARQPDLQDELRAEISAARIAFKGDMVQMVKMIPLLKAALKETLRLHPVAMSLPRFIT
EDTVIQNYHIPAGTLVQLGVYAMGRDHQFFPKPEQYCPSRWISSKRQYFKSLGFGFGP
RQCLGRRIAETEMQIFLIHMLENFRIEKQKQIEVRSKFELLLMPEKPIMLTIKPLNAS
R

>CYP11A2 zKp91C1 80% to BC054701 CYP11A1 zebrafish
135289 MARWSLSARLDQSVSSLKHLLQVIVTRSGRAPAIGLQDSTVRPFNEIPGQWRNSLKSVF 135465
135466 AFAKMGGLRNIHRIMVHNFNTFGPIYR 135546
140793 EKVGFYESVNIIKPEDAAILFKAEGHYPKRLTIDAWTAYRDYRNRKYGVLLK 140948
141023 DGEDWKSNRIILNKEVISPKVQGNFVPLLDEVGQDFVARVNKKIERSGQNQWTTDLSHELFKFALE 141220
141612 AVSAVLYGERLGLLLDYIDPDSQRFIDCITLMFKTTSPMLYLPPGLLRPIRSK 141770
141771 IWRNHVEAWDGIFNQ 
141920 ADRCIQNIYRQLRKNPEGNGKYTGVLASLLMLDKLSIEDIKASVTELMAGGVDT 142081
144029 TAITLLWTLYELARNPDLQEEIRAEISAARIASKGDMVQMLKMIPLVKGTLKETLR 144196
144540 LHPVAVSLQRYITEDIVIQKYHIPAG 144617
149492 TLVQLGLYAMGRDHQVFPNPEQYLPSRWVNSQNHYFKSLSFGFGPRQCLGRRIAETEMQLFLIH 149683
149788 MLENFRIEKQRQMEVKSMFELILLPEKPIMLTIKPLNSSR 149907

>CYP11B 70% to Fugu 11B1 NA11197 (C-term) NA2834 (46-146) BI880530 AL916948 Z35724-a4708b08.q1c zfish44908-889d03.q1k
      MFSSCAGSVCARPHLCVRASVCVRPLHQSSRSA
  998 GAARLFQEIPDTGSNGWMNLLRFWRDGRFSRMHKHMEESFRRLGPIYR 855
  298 EHLGSQSSVNIMLPMDTGELFRSEGLHPRRMTLQPWATHRETRRHSKGVFLK 140
      NGTEWRADRLLLNREVMVSSSVHRFLPLLDEVAQDF
      CRSLRRRVQADGFEKAGQHTLTLDPSPDLFRFALE
      ASCHVLYGERIGLFSSCPSDESERFISAVERMLATTP
      PLLYLPPRLLLRLRASLWTTHATAWDDIFSH
      AEQRIQRSYQRLQARASAAPDCSFPGVLGKLMEAGQLSLELIQIHITELMAGGVDT
      TAVPLQFALFELARNPDVQECVRAQVLSSWRQASGDPLNALQGAPLLKGTLKETLR (2?)
      LYPVGITVQRYPVRDIVLQNYHVPAG (0?)
 9295 TLVQVCLYPLGRSAEVFSRPECFDPSRWSADADAGSAGGFRSLAFGFGSRQCVGRRI 9465
 9466 AENEMQLLLMH 9498 (0?)
11046 ILRTFKLTVSSTEELSTKYTLILQPECPPRITFSTLTHQH* 11168

>CYP11B1 Fugu. Is the fugu seq wrong at yellow?
8573  MWLPAGAGVRARSARGFRTAAGAVVDGKVGACKGAEVPESKKGVDGQVRSFEEIPHTG 8746
8747  RNSWVNLLRFWREDRFRHLHKHMERNFNSLGPIYR (2)
      EPVGAPNSVNIMLPSDISELSRSEGLHPRRMTLQPWATHRETRKHGKGGFHK (2?)
254   NGEEWRADRLLLNKEVMMSEAVRRFIPLLDEVAQDCHMMQTKVEREGRGERGKRSLTINPSPDLFRFALE
11719 ASCHVLYGERIGLFSSSPSLESQKFIWAVERMLATTPPLLYLPHRLLLHLGAPLWTQHASAWDHIFTH 11519 (1)
11438 AEERIQRGYQRLSHSQSRGPEGGGRYKGVLGQLMAKGQLSLELIKANITELMAGAVDT 11265 (0)
11178 TAVPLQFALFELGRNPEVQQRVRQQVQESWAQAGGDPQKALQEAPLLKGTIRETLR 11011 (2)
10465 LYPVGTTVQRYPVKDIVLQNYHIPAG (0) 
      TMVQACLYPLGRSAEVFEDPLRFDPGRWGKSREEGQRGGGTGFRSLAFGFGARQCVGRRIAENEMQLLLMH 10097 (0)
 9896 ILLGFDLSVPSSEDIKTMCTLILMPETPPKITFTKL* 9786

>CYP17A NM_212806 NM_201173 AI883222 fd17f05.y1
MAEALILPWLLCLSLFSAVTLAALYLKQKMNGFVPAGNRSPPSL
PSLPIIGSLMSLVSDSPPHIFFQDLQKKYGDLYSLMMGSHKLLIVNNHHHAKEILIKK
GKIFAGRPRTVTTDLLTRDGKDIAFADYSSTWKFHRKMVHGALCMFGEGSVSIEKIIC
REASSMCEVLTESQNSAVDLGPELTRAVTNVVCALCFNSSYKRGDAELESMLQYSRGI
VDTVAKDSLVDIFPW LQIFPNKDLRILRQCISIRDKLLQKKYEEHKVTYSDNVQRDLL
DALLRAKRSSENNNSSTRDVGLTEDHVLMTVGDIFGAGVETTTTVLKWSIAYLVHNPQ
VQRKIQEELDSKIGKERHPQLSDRGNLPYLEATIREVLRIRPVSPLLIPHVALQDSS V
GEYTVQKGTRVVINLWSLHHDEKEWKNPELFDPGRFLNEEGDGLCCPSGSYLPFGAGV
RVCLGEALAKMELFLFLAWILQRFTLEMPTGQPLPDLQGKFGVVLQPKKFKVVAKVRA
DWEKSPLMQHC

>CYP17A2 NA10451 66% to CYP17A2 FUGU 53% to zebrafish 17A1 
zfish44906-4740a11.p1k AW077606 
zfish44906-4768e03.p1k (exons 5-7 made from non-overlapping contigs)
missing exon 1
 972 YGPLFGLYAGPHLTLVVSEIGLVREVLLQRGREFAGRPKM 1091
1427 VTTDLLTQGGKDIAFADYSPLWKNHRRLVHSSFTKFGEGSNKLQTI 1564
2943 VQEAADSLCEELQACRGQSSDLSVVLMRAVTNVICRLVFSSSYQPSDPELQTVIQYNDGIVQTI 3134
3135 ARGGLVDIFPWLK 3173
 70  IFPNKDLKRLKECVSIRDQLLYKKLLEHK (0)
     KSLTPGEPRDLLDALLIGQQRGSGGADDITEDHVLMTAAEAFGAGVETTSTTLLWTIAFLLHHPQ 432 (0)
 546 LQERVQAELDECVGVDRPPCLSDRPHLPLLDAVLCEVMRIRPVSPILIPHVAMQDTR 376
7906 LGGHSVPKGTRVLVNMWAIHHDPKHWTQPEQFNPG 8010
8203 RFLEPSGKKKTQSSFLPFGAGPRVCVGESLARIELFLFVSRLLQRFSFSCPSEASLPDLQ 8382
8383 GRFGVVLQPERYTVTVTPRH* 8445

>fugu 17a2
1198 MVTVGSFLIFRRPVRGSEPGSEAGPPRVKVPCISWVPVLGSLPWLRGGRPLHLIFTQLSYR 1380 (2)
1600 YGPLFALYLGPHLTVVVNNHQHAREVLLLRGKDFAGRPRM 1719 (0)
1797 VTTDLLTRGGKDIAFSDYCPLWKSHRRLVQNSFTLFGEGTSRLQDM 1934 (1)
2061 VLAAVDSLCEELLSMEGRGFDPAPAVTRAVTNVVCMLVFSATYRHGDSELQEVLRYNDGI 2240
2241 VQTIAGGGLVDIYPWMK 2291 (0)
2372 VFPNKTLSKLKACIAVRDRLLTHKLEEHK 2458 (0)
2622 ATLTDNQPRDLLDALLMGQVGRGRRKGSGRVEEDIITEDHVLMTAAEAFGAGVETTSTTLLWILAYLLHHPQ 2837 (0)
2925 VQERVQKELDDHVGSERPVRVSDRARLTYLDCVINEGMRIRPVSPVLIPHTAMTDSR 3074 (2)
3870 IGGHHISRGTRVLVNMWSIHHDSAHWDKPDLFNP 3971 (1)
4519 DRFRDHQGQRVTPSCFLPFGAGPRVCVGESLARLELFLFLSSLLQRMSFRLPNGA 4692
4693 SPPDLQGRMGVVLQPVPYKVVVTPRVG* 4776

>CYP17 FROG CK805326 AGENCOURT_19148075 NICHD_XGC_Te2 Xenopus laevis cDNA clone
229 IFPNKDLDILKRSVAIRDKLLQKKLKEHKEAFCNEEVNDLLDALLKAKLSMENNNSNIS 405
406 QEVGLTDDHLLMTVGDIFGAGVETTTTVLKWTIAYLLHYPEVQTKIQEELDFKVGFGRHP 585
586 VLSDRRILPYLDATISEVLRIRPVAPLLIPHVALQES 696

>CYP19a AF183906 AF004521 AF226620 AF183907 (alt splice) ovarian
MAGDLLQPCGMKPVRLGEAVVDLLIQRAHNGTERAQDNACGATA
TILLLLLCLLLAIRHHRPHKSHIPGPSFFFGLGPIVSYCRFIWSGIGTASNYYNSKYG
DIVRVWINGEETLILNRSSAVYHVLRKSLYTSRFGSKLGLQCIGMHEQGIIFNSNVAL
WKKVRAFYAKALTGPGLQRTMEICTTSTNSHLDDLSQLTDAQGQLDILNLLRCIVVDV
SNRLFLGVPLNEHDLLQKIHKYFDTWQTVLIKPDVYFRLDWLHKKHKRDAQELQDAIT
ALIEQKKVQLAHAEKLDHLDFTAELIFAQSHGELSAENVRQCVLEMVIAAPDTLSISL
FFMLLLLKQNPDVELKILQEMDSVLAGQSLQHSHLSKLQILESFINESLRFHPVVDFT
MRRALDDDVIEGYNVKKGTNIILNVGRMHRSEFFSKPNQFSLDNFQKNVPSRFFQPFG
SGPRSCVGKHIAMVMMKSILVALLSRFSVCPMKACTVENIPQTNNLSQQPVEEPSSLS
VQLILRNTL

>CYP19b AF183908 AF226619 AF120031 brain
MMEHVVKDAVNIGAVVQGTLLLLTGTLMLILLHRIFGVKNWRNQ
SALPGPGWWLGLGPVLSYSRFLWMGIGTACNYYNEKYGSIARVWINGEETVILSKSSA
VYHVLKSNNYTGRFASAKGLQCIGMFKQGIIFNSNIAKWKKVRTYFTRALTGPGLQKS
VEVCVSATNRQLDVLQEFTDASGHVDVLNLLRCIVVDVSNRLFLRIPLNEKELLIKIH
RYFSTWQTVLIQPDIFFKLDFVYRKYHLAAKELQDEMGKLVEQKRQAINNTEKLDEMD
FATELIFAQNHDELSVDDVRQCVLEMVIAAPDTLSISLFFMLLLLKQNSAVEEQIVQE
IQSQIGSRDVESADLQKLNVLERFIKESLRYHPVVDFIMRQSLEDDYIDGYRVAKGTN
LILNIGRMHKTEFFKKPNEFSLENFENTVPSRYFQPFGCGPRACVGKHIAMVMTKAIL
VTMLSRFTVCPRHGCTISTIRQTNNLSMQPVEEDPDCLAMRFIPRAQNSNGETADNRT
SKE

>CYP20 Danio rerio (zebrafish) ctg10765 74% to fugu 
 9501 MLDFAIFAVTFVIILIGAVLYLYP (0) 9572
      SSRRASGVPGLNPTEEK (2?)
      DGNLQDIVNKGSLPEFLVGLH
      DEFGSVASFWFGARPVVSLGAVNQLRQHINPNWT (1) 10024
12291 TDSFETMLKSLLGYQSGSGVGLTESMMRKKVYEGAINKTLENNFPLLLQ (0) 12439
12929 QVEELVDKWASYPKSQHTPLCAHFL 13003 
13003 GLAMKAVTQLAMGSRFRDDAEVIRFRKNHEA (0) 13095
15738 IWSEIGKGYLDGSLEKSSSRKAHYES (1?) 15815 
15897 ALAEMESVLKSVAKQRPGQGSSQSFVNYLLQANLTERQ (0) 16010
16583 VMEDGMVFTLAGCVITAN (1) 16636
17689 LCIWAVHFLSVSEAVQDRLYHELVEVLGDELVSLEKIPQLR (2) 17811
19293 YCQQVLNETVRTAKLTPVAARLQEVEGKVDQHVIPKE (0) 19403
21269 TLVIYALGVVLQDADTWSLPYR (2) 21334
21425 FNPDRFAEESVMKSFSLLGFSGSQACPELR (2) 21514
      FAYTVATVLLSTLVRRLRMHRVDGQVVEARYELVTTPKDDTWITVSKRN* 

>CYP21 AL953915.4   Zebrafish exon 7 boundaries not certain, no good EST or mRNA in vertebrata. N-term not clear
     MCFSVVSVVLLLFILWMLVVKFWRQSHRRTDG (0) 
4754 IVILICVSFYCPIAVFPKLLHSLYKLFFSTVSPTISGPRSL PLLGNMLDLAQDHLPIHLTALA 4942
4943 KCYGNIYRLNCGSTS 
5738 AMVVLNNSEIIREALVKKWSDFAGRPYSYTG
5918 XDIVSGGGRTISLGDFSEEWKAHRRVTHSALQRCTTDSLHSVIEKQAQHLCQ 6070
7187 VLRDYSGKAVDLSEDFTVASSNVITTLTFSKA 7282
7369 YDKSSAELQKLQECLNEIVSLWGSPWISALDSFPLLR
     KFPNPPFSRLMKEVARRDELIGKHIEEFK 7665 (0)
     KSEHKEGGTLTSSLLKCLEPQQGAANHT (0)
 8868 TLTDTHVHMTTVDLLIGGTETIAALLNWTVAFLLHRPE 8981
14582 VQDKVYEELCCVLDVRYPQYSDRHKLPYLCALISEMLRLRPVAPLAVPHRAIRNS 14746
16875 SIAGHFIPKNTIIIPNLYGAHHDPEVWDDPYSFKP 16979
17077 ERFLEGGGGSLRSLIPFGGGARLCLGEAVAKMEMFLFTAYLLREFKFLPASKEEPLP 17247
17248 ELRGVASVVLKVKPYTVIAHPREQ* 17322

>CYP24 ctg12249 CN507760.1 69% to human CYP24 except N-term 76% to fugu CYP24
      MRAHLQRAPQILELLKKKTAGLQHCKPTSSVCVLDSKDAAGSAPCAHS
90158 LDSIPGPTNWPLFGSLIEVIRNGGLKRQHETL 90253
91424 IHFHKKFGKIFRMKLGSFESVHIGSPCLLEALYRKEGSYPERLEIKPWKAYRDMRDEAYGLLIL 91615
91705 EGRDWQRVRSAFQQKLMKPTEVMKLDGKI 91791
      SEVAADLIKRIGKVNGKMDDLYFELNKWSFET
92515 ICYVIYDKRFGLLQDSVSKEGMDFITAVKT
      MMSTFGTMMVTPVELHKTLNTKTWKDHTEAWDRIFST 92850
95260 AKHYIDKNLQKQSNGEADDFLSDIFHNGNLTKKELYAATTELQVGGVET 95406
      TANSMLWVIFNLSRNPCAQGKLLKEIQDVVPAGQTPRAEHIKNMPYLKACLKESMR
      VSPSVPFTSRTLDKDTVLGDYTLPKG 99051
      TVLMLNSQAIGVSEEYFDNGRQFRPERWLEEKSSINPFAH
      VPFGVGKRMCIGRRLAELQIQLGLCWILRDYK
      IVATDLEPVDSLHSGTLVPSRELPVAFVPR 101033

>CYP26A1 U68234
MGLYTLMVTFLCTIVLPVLLFLAAVKLWEMLMIRRVDPNCRSPL
PPGTMGLPFIGETLQLILQRRKFLRMKRQKYGCIYKTHLFGNPTVRVMGADNVRQILL
GEHKLVSVQWPASVRTILGSDTLSNVHGVQHKNKKKAIMRAFSRDALEHYIPVIQQEV
KSAIQEWLQKDSCVLVYPEMKKLMFRIAMRILLGFEPEQIKTDEQELVEAFEEMIKNL
FSLPIDVPFSGLYRGLRARNFIHSKIEENIRKKIQDDDNENEQKYKDALQLLIENSRR
SDEPFSLQAMKEAATELLFGGHETTASTATSLVMFLGLNTEVVQKVREEVQEKVEMGM
YTPGKGLSMELLDQLKYTGCVIKETLRINPPVPGGFRVALKTFELNGYQIPKGWNVIY
SICDTHDVADVFPNKEEFQPERFMSKGLEDGSRFNYIPFGGGSRMCVGKEFAKVLLKI
FLVELTQHCNWILSNGPPTMKTGPTIYPVDNLPTKFTSYVRN

>CYP26B1 NM_212666 87% to fugu 26B1 AI721901 fc26h10.y1, zfishG-a606d09.q1c
MLFESFDLVSALATLAACLVSMALLLAVSQQLWQLRWTATRDKS
CKLPMPKGSMGFPIIGETCHWFFQGAGFHASRRQKYGNVFKTHLLGRPLIRVTGAENV
RKVLMGEHSLVTVDWPQSTSTLLGPNSLANSIGDIHRKRRKIFAKVFSHEALESYLPK
IQQVIQETLRVWSSNPDPINVYRESQRLSFNMAVRVLLGFRIPEEEMHCLFSTFQEFV
ENVFSLPIDLPFSGYRKGIRARDSLQKSIEKAIREKPLHTQGKDYTDALDVLLESAKE
NNTELTMQELKESTIELIFAAFATTASASTSLVMQLLRHPAVLEKLREELRSCGLLHD
GCLCQGELRLDSIISLKYLDCVIKEVLRLFAPVSGGYRIATQTFELDGVQVPKGWSVM
YSIRDTHDTSAVFKDVEAFDPDRFSPERSEDREGRFHYLPFGGGVRSCLGKQLATLFL
KLLAVELAGGSRFELSTRTFPRMISVPVVHPTDGLRVKFFGLDSNQNQIMAKSDEMLD
ATV

>CYP26C1 ctg13279 ZEBRAFISH EXON 5 HIGHLY VARAIBLE IN LENGTH IN DIFF SPECIES
IN THE LOOP BETEWEEN I AND J HELICES zfishK-a167e03.q1c Z35723-a97d11.q1c
13394 MFDHGFCLVSALLSVADAVLPTVLLLAVSRLLWEFRWSITRDKTCKLPLPQGSMGWPLVGETFHWLFQ 13597 (0?)
16231 GSSFHISRREKHGKVFKTHLLGKPLIRVTGAENIRKILLGEHTVVCTQWPQSTRIILGP 16407
16408 NTLVNSVGDLHKRKRK 16455 (0?)
16613 VLAKVFSRGAQ*APFIRLQDVVEFDIAKWCNKTGFVEVTSAAESLTFRITVGVVLGMHLK 16792
16793 DQQITYLSKALEQLMNNLFSLPIDTPVSGLRK 16888 (0?)
18631 GIRAREILHSAMEKIIEEKLKKQQASDYCDAFDYMLSSARENDYELTMQELK 18786 (0?)
SPAVELIFAAHSTTASASTSLIMQLLRHPDVSERARAELESEGL 
ITDGHGHCRSRCNGNEEGEAAEKSTSDRRSAINKATYFEAGDKEEGR
RSRTHVPYLSLEKLSQLSYLDCVVKEVLRFLPPVSGGYRTVLQTFELN
22525 GYQIPKGWSVMYSIRDTHETAEAYQNPEFFDPDRFCVGREESKSERFSYVPFGGGVRR 22698
22699 CIGRELALIVLKTLAVELLATADCTLATQTYPRMQTVPIVHPVNGLHVFFNYR 22857
TQGIERNRRESTHI*

>CYP27A.a BX321915.3 59% to 27A1 fugu zfishG-a34c11.p1c
28992 MAVSFALSSAERLGWCFLRPTTAATGFRRAAGNSAAASVSVQDGHRKLKTEA 27837
27836 DLPEIKIFTMLYQMLFKGYLNSVHELQ 27756 (0)
25958 LYQKQVYGPLWKINAGNLQGISITSVELLEELLRKDEKYPCRGYMTLWTEHRDLRGISYGPFTE 25767 ()
      EGEKWYKLRAVLNKRMLHPKDSLQYGDVVNAVITDFIKRIYYLREMSPTGDLVSNLTNELYRFSLE
      GIASILFETRIGCLEKEIPAETQEFINSIAQMFTYNMHVALLPNWTRNYLPFWQKYIDGWDGIFKF
      GTKMINLKMEAIQTRLDTNQEVAGEYLTYLLSSGKMSCKDVYGSVSEVLLAGVDT
      TSNTMLWALYLLSKDPAAQETLHQEVTKVLKGDRIPTAEEVNSMPFLKAVIKETLR
      LYPVVPVNSRLIAESEVIIGEYLFPKK (0)
      TTFNLFHYAISHDEKVFPEPQKFKPERWLRDGRTRPNPFGSIPFGFGVRACVGRRIAELEMHLALAR
      LIKLFEMRPDPTVGEVKANFRSVLVPNKKVNLHFVERQKTET* 17333

>CYP27A.b BX321915.3 61% to 27A1 fugu missing C-term
46923 MAVCFALSSAERLGFGFLRPTAAATGFRRAAGNAAAASVSVQDGHRKLKTEA 46768
46767 DLPEIKIFTMLYQMLFKGYLNSIHELQ 46687 (0)
46408 IYQKQVYGPLSKINSGNLQGISISSVELLEELLRKDEKYPCRGYMTLWTEHRDLRGIGYGPFTE 46217 ()
      EGEKWYKLRAVLNKRMLHPKDSLQYGDVVNAVITDFIKRIYYLREMSPTGDLVSNLTNELYRFSLE
      XIASILFETRIGCLEKEIPVETQEFINSIAQMFTYSMHVALLPNWTRNYFPFWQKYIDGWDGIFKF
      GTKMIDMKMEAIQKRVDTNQEVAGEYLTYLLSSGKMSSKDVYGSVSELLLAGVDT 1183
      TSNTMLWALYLLSKDPAAQETLYQEVTKVLKDDRIPTAEEVNSMPFLKAVIKETLR 1000
      LYPVVPVNSRLIAETEVVIGEYFFPKK (0)
      TTFNLCHYAISHDEKVFPEPQKFKPERWLRDGRTRPNPFGSIPFGFGVRACVGRRIAELEMHLALAR
40957 LIKLFEMRPDPTVGEVKANFRSVLVPNKKVNLHFVERQKTET* 40849 

>CYP27A.c BX321915.3 59% to 27A1 fugu
54468 MAVCFALSSAERLGWCFLRPTAAATGFRSAAGNAAAASVSVQDGHRKLKTEADLPEI 54298
54297 KIFTMLYQMLFKGYLNSVHELQ 54232 (0)
      LYQKQVYGPLWKINAGNLQGISISSVELLEELLRKDEKYPCRGYMTLWTEHRDLRGISYGPFTE 53897 ()
      EGEKWYKLRAVLNKRMLHPKDSVQYGDVVNAVITDFIKRIYYLREMSPTGDLVSNLTNELYRFSLE
      XIASILFETRIGCLEKEIPAETQKFINFIAQMFTYSMHVALLPNWTRKYFPFWQKYIDGWDGIFKF
      GTKMIDMKMEAIQKRVDTNQDVAGEYLTYLLSNGKISRKDVYGSVSELLLAGVDS
      TSNTMLWALYLLSKDPEAQETLYQEVTKVLKDDRIPTAEEVNSMPFLKAVIKETLR
      LYPVVPVNSRLIAETEVVIGEYFFPKK (0)
      TTFTLCHYVISRDEKVFPEPQKFKPERWLRDGRTRPNPFGSIPFGFGVRACVGRRIAELEMHLALAR
      LIKLFEMRPDPTVGEVKANFRSVLVPNKKVNLHFVERQKTET* 49254

>CYP27A.d BX321915.3, BC055637 60% to 27A1 fugu
65501 MAVCFALSSAERLGIGLGFLRPTAAATGFRRAAGNAAAASVSVQDGHRK
      LKTEADLPEIKIFTMLYRLLFKGYLSRMHELQ (0)
      LYEKQLYGPLYKINVGNFQSVALNSVDLLEELLRKDEKFPSRGDMTLWTEYRDMKGIGYGPFTE
      EGEKWYKLRAVLNKRMLHPKDSVQYGDVVNAVITDFIKRIYYLREMSPTGDLVSNLTNKLYRFSLE
      GISSILFETRIGCLEKEIPAETQHFINSIAQMLTYSMPVVFMPNWTRNYLPFWQRYIGGWDGIFK
      FAGKMIDMKMEALQKRVDANQEVAGEYLTYLLSNGKMSSKDVYGSVSELLLAGVDT
      TSNTMLFALYHLSKDPETQDILYQEVTNVLKDDRIPTAQEVNTMSYLKAVIKETLR
      LYPVVPMNARLIAENEVVIGGHLFPKN (0)
      TTFTLCHYAISRDEKVFPEPQKFKPERWLRDGRTRPNPFGSIPFGFGVRGCVGRRIAELEMYLALAR
      LIKLFEIRPDPTVGEVRSLNRTVLAPDRKVNLHLVERKKTEA* 56151

>CYP27A BQ258463 new
ILEKGRYGPIYRNGMNAVSVSTAKLLGEVLRNDDKFPNRGDMSIWKEYRDLRGYGYG
PFTEKDERWYNLRAVLNKRMLRPKDALQYGDTIGEVVTDFIRRIYFLRQRSPTGDVVTDL
NNELYHFSL


>ctg11505 CYP27A3 LIKE FRAGMENT EST = CD283382 69% TO 27A3 FUGU 
fi80d01.y1 SPANS N-TERM zK114F15T7
>ctg11136 96% TO 27A3 74% to CYP27A1
>ctg30308 
 878 MFSNSLLRTGLFLCKQDCSGIKCLTSMFLNARTTSTLIGGDKQKTMDDLDGPS 720
 719 FLTSLYWLFGKGYFQTTHQMQIEHSKIYGPLWKSKYGPLVIVNVASAHLIKQVLRQ
     EGRHPIRTDMPHWRGYRKLRNHAYGPLTEM
4645 GPEWQRIRSILNPRMLKPKHVSNYTNAINGVVSDFIEKMAKLKTTKGNDVMVYDVAGELYKFAFE 4451
1494 GISSVLFETRMGCLNDEIPEETQKFIFSVGEMFRLSPIVILFPKFLWPYMPF 1339
1338 WKHFVAVWDHLFKV 1297
 613 ADELVQQKMTEIQEKVKTGSPVEGEYLTHLLISEQMSFTEVLGSITELLLAGVDTVSI 440
 279 TISWALYHLAREPEIQQKLHEEVVSVCPGDKTPSSDDITRMPLLKAIVRETLR 121

292075 LYPVVPANARVVAQNEIVVGDHLFPK 291998
291917 QTLFHLCHFAVSYDETVFPDPFAFLPQRWIREQKQLSQH
291800 PFGSVPFGFGIRACLGRRVAELEMYLLLSR 291711

61568 LIKRYEVRPDPSGKTVKPITRTLLVPATSIDLQFIDR*

>CYP27A3 Scaffold_6002 Length = 16767 missing 7 aa
= LGS139924.x1 57% to 27A1 I-helix LGS125183.x1 Cyp27a1
FS:S002565 Scaffold_2565
First 16 aa and 49-81 supported by EST from AU050037 Paralichthys olivaceus
49 on also supported by AW343479 zebrafish EST
LPC42076.x1 39% to 27A1 202-276 79% to LPC42075.x1 Exon 4
     MFRNRLLTVGLRASVPHREGLHRTAVNYAGARRRHASSAATEITEHNVR
     QKTMEDLGGPSFLTTLNWLFLKGYLPKTQQMQ (0)
4619 VEHSKIYGPLWKSKYGPMVVVNVASADLIEQVLRQEGRHPVRTDMPHWRRYRALRNQAHGPLTE (2) 6106 gagt
5422 XXXXXXXIRSILNPRMLKPQHVSSYGITINDVVTDFLEKLVWLRAKDGGGVMVNDVAGELYKFAFE (1) 5249
4825 GISSVLFESRMGCLNDEVPEETQKFIYSVGEMFRLSAVVVLFPQSVWPYLPLWKKFVAAWDYLFKV (1) 4604
1891 AEQMVQKKMEEIQNKVDLHQDVEGAYLTHLLLSEKMTVTEILGSITELLLAGVDT 1715
1661 TSNTISWALYQLAQNPSIQDQLYHEVRSVCPGNKMPDSDDIAQMPYLKAVIRETLR
     LYPVVPGNARVTVDKEIVVGGYLFPKQ (0)
754  TLFHLCHYCVSHDENIFPNSRVFQPERWLRGREEKSKQHPFGSVPFGFGVRACLGRRV 581
580  AELEMYLLLSR (0)
     LIRRFEVRPDPNGAEVKPITRTLLCPATPINLQFLDRGAQRAPGPAAGASL*


>CYP27B1 ctg10726 72% TO 27B1 FUGU from multiple contigs
568 MMMVLHQALKVTGRSALPLLRFAERWADVIRAPPTPQVKTLEQMPGPSPARFIRDLFMKRGFS 380
379 RLHQLQ 362 ()
337 LEGRQKYGPMWKASFGPILTVHVAEPELIQQVLRQEGQHPMRSELSSWKDYRALRGEG 164
163 YGLLT 149 ()
158 SEGEEWQCVRSLLSKHMLRPQAVEAYDGALNAVVSDLLQKLKLRSQESSSRIVSDISAEF 337
338 YRFGLEG 358 ()
281 ISSVLFESRIGCLDAVVPVETERFIQSINTMFVMTLLTMAMPQWLHRLLPKPWDTFC 451
452 RCWDVMFEF 478 ()
46  AKGHIDQRLQQEKQKLECGEQLEGRYLTYFLSQAGLPLTSVYSNVTELLLAGVDT 210
592 ISSTLSWSLYELSRHPDVQTALRXEVLSVMKGRRSVPQASDVAAMPLLKAVVKEIL 425 ()
345 RLYPVIPANARVINKDIEVGGYVIPKN 265 ()
84579 TLITLCHYATSRDP 84620
84620 QQFRDPDSFRPQRWGDRSDRSHPYATVPFGVGKRSCIGRRIAELEVYLALSR 84775
85167 ILMHFTVEPARQDDTVHPMTRTLLVPERQIDLRFTER* 85280

>CYP27C1 ctg14633 70% TO FUGU CYP27C1
      MARKNLLQESCRQLLIQTHGLHKSVASGSLEIAAHSQADLKEESAVSPAEEVQ
      KAARVKSLKEMPGPSTVANLLEFFYRDGFSRIHEIQ 46230
      MEHAKKYGKIFKSRFGPQFVVSIADRDMVAQV 48886
48887 LRSESATPQRGNMESWKEYRDLRGRSTGLISA 48982
      EGDEWLKMRSVLRQLIMRPRDVAVFSSDVT 50683
50683 DVVADLVKRVKTLRSQQDDSQTVLNINDLFFKYAME 50790
      GVATILYETRLGCLENEIPKMSQEYITALHLMFSSFKTTMYAGAIPKW 52654
52655 LRPIIPKPWEEFCSSWDGLFKFS 52723
52813 IHVDKRLSEIKKQMEKSEEIKGGLLTHMLVTREMNLEEIYANMTEMLLAGVDT 52971
55090 TSFTLSWSTYLLARHPTIQQQIFEEVDRVLGGRVPTGEDVPYLPLIRGLVKETLR 55254 ()
      LFPVLPGNGRVTHDDLIVGGYLIPKG 55452 ()
58126 TQLALCHYSTSMDEENFPRPEEFRPDRWIRKDASDRVDNFGSIPFGYGIRSCVGRRIAEL 58305
58306 EMHLALTQ (0)
      LLQNFHIEVSPQTTEVHAKTHGLLCPGASINLRFTDRK* 58539

>CYP39 ctg9833 48% to 39A1 AL929058.4 96727-71438
130332 MEWITLILTVSVVIISFHLLFGKSHPNAPPCIRGWIPWFGAAFEFGKAPLHFIQQARAK 130156 (0?)
127387 YGPVFTVVAAGKRMTFVTLNEDFRVFFTSKDVDFEQAVQEPVHNT 127253
127049 ASISKDNFFESHPTCSAIIKGRLTPGNTAMLSPHLCEEFNDHLESLGSEGSGQLNELIK 126873
125860 SVMYPSVMSNLLGRCNSPSSALSRQEFLEKFTTYDEGFEYGSQLPEMFLK 125711
124805 EWSNSKHWLLSL 124770 LRKMVIKSEETLYSESDRK
123739 TLLQHLAASISEQYLPNYGLLLLWASLANAIP 123674 (0)
       VTFWAVAFILSNPTAYKIVMDQINSVLGRQG
120968 KQKTKVTLDDLQQMPYVKWCIMEAIRLRAPGAITRKVVRPLKLX 120840
116801 NYVIPPGDMLMLSPYWAHRNPKYFPDPEDFKP 116706
112276 ERWETADLEKNVLLEGFVAFGGGKNQCPGR
105126 WYAIMELHMFVALILYKFEFAQLDPMPK 105043

>CYP39A1 human AC008104 AL035670 note heme region exon corrected 1/18/02
MELISPTVIIILGCLALFLLLQRKNLRRPPCIKGWIPWIGVGFEFGKAPLEFIEKARIK
YGPIFTVFAMGNRMTFVTEEEGINVFLKSKKVDFELAVQNIVYRT
ASIPKNVFLALHEKLYIMLKGKMGTVNLHQFTGQLTEELHEQLENLGTHGTMDLNNLVR
HLLYPVTVNMLFNKSLFSTNKKKIKEFHQYFQVYDEDFEYGSQLPECLLR 
NWSKSKKWFLELFEKNIPDIKACKSAKDNSM 
TLLQATLDIVETETSKENSPNYGLLLLWASLSNAVP
VAFWTLAYVLSHPDIHKAIMEGISSVFGKAG
KDKIKVSEDDLENLLLIKWCVLETIRLKAPGVITRKVVKPVEIL
NYIIPSGDLLMLSPFWLHRNPKYFPEPELFKPERW
KKANLEKHSFLDCFMAFGSGKFQCPARW
FALLEVQMCIILILYKYDCSLLDPLPKQ
SYLHLVGVPQPEGQCRIEYKQRI

>trout CYP39 73% to zebrafish BX298944 
10  MDVITLVLFLVVLAISAHLLFGGNYPNAPPCIKGWIPWFGVAFEFGKSPLTFISQARDKY 189
190 GPVFTVVAAGKRLTFVTLHEDFRTFFMSKDVDFEQAVQEPVHNTASISKESFYKFHPACN 369
370 TLIKGRLTPGNVAQLTDHLCEEFNDHLETLGDQGSGGLNELVRAVMYPAVMSNLLGKYNS 549
550 PGSPFTMEQFREKFAIYDEGFEYGSQL 630

>CB512602 CYP39 Salmo salar cDNA. 71% to zebrafish
2   EVVTLVLSLVILAISAHLLFAGNYPNAPPCIKGWIPWFGVAFEFGKSPLTFISQARDKYG 181
182 PVFTVVAAGKRLTFVTLHEDFRTFFMSKDVDFEQAVQEPVHNTASISKDSFYKFHPACNT 361
362 LIKGRLTPGNVAQLTDHLCEEFNDHLETLGDQGSGGLSELVRAVMYPAVMSNLLXKYNSP 541
542 GSPFTMEQFKEKFAIYDEGFEYGSQL 619

>CYP39 BU226060 Gallus gallus cDNA clone ChEST772g3 5' 49% to zebrafish
          Length = 769
CN778112 Chicken Lymphoid cDNA library (pgn2c) Gallus
Length = 764 57% to human
AI979980   pat.pk0008.g11 chicken activated T cell cDNA
BG710422   pgl1n.pk003.l11 Normalized Liver Library Gallus gallus
BG712800   pgl1n.pk013.p8 Normalized Liver Library Gallus gallus
    AAAVLLAALLAVAVVAWVLFPPSEPRRPPCIGSRVPCLGAAFRLA
18  RAPLEFIERARAEHGPIFTVFALGKRFTFVTEDEGAEVFFTSKDLNFEQAVQRVVANAVS 197
198 VPAEAFYQNHGRLYSMMKGKMGPSNLHMFTGTLCKELHEHMAHLGTAGTGDLMELVRHIM 377
378 YTAVVNTLFGKGACPTSHSELREFEEHFWKYDEDFEYASQMPECFLRNWSKSKKWLLKLF 557
558 EKVVSDAERTNPSETTSKTLLQHLLDNLQGKHLX
661 PNYGLLMLWASQANAVPIAFWTLVF
764 ILSSPSVYKKVMEDLTSVFGNAGKDEIEVSEEDLKXLPYIKWCTLEAIRLRSPGAITKKV 585
584 IKPIRIQSFTIPAGDMLMLSPYWLHRNPKYFPDPEMFKPDRWKEANLEKNAFLDGFVAFG 405
404 GGNHQCPGRWFAIMEIQLLVALFLYKYEFVLLDAVPKESPLHLVGTQQPLTPFRVQYKGWE*

>CYP39 CK798826   AGENCOURT_18789924 NICHD_XGC_Te2N Xenopus laevis cDNA clone
CN316812   AGENCOURT_22004784 NICHD_XGC_Te2N Xenopus laevis cDNA clone
CD325940   AGENCOURT_14164113 NICHD_XGC_Eye1 Xenopus laevis
49% to human
    MQIASVSALFSPTAALGLLVALLTAVLVRYLLPNASHKPPYPPCIRGWIPWFGAAFEMGKAPLEFIARAKEKHGPVFT 222
223 VLAAGNRLTFLNGKEGVSAFFSSKDADFQQAVQKPVQHTASINKADFMKSHSSIHETMKL 402
403 RLSQNRLNLYFDRIRNEFGTRIELLDPEGTEDLFTLVKQVMYPAVVDTLFGKGLCPTGKD 582
583 NLKEFAEHFWKFDEGFEYGSQLPEFLLRDWSQSKQWLLSLFQKIVIEAEMKHPFRETSKT 762
763 LYQHVLDTLKGIATLHNSLLPLWXXXXXXXXX
737 TFGXLPFIISDPLVYKTAMDEIYSVFGKTGNSPLNINEAELKRLPFIKNCVLEAIRLRSP 558
557 GAITRKAVQPLKIYNYIIPAGDLLMLSPYWLHRDPVLFPEPEMFRPERWSKANLEKNVFL 378
377 EGFVAFGGGKYQCPGRWFALMEMHMLVVMMLYKYEFSLLDPLPKQSNLHLVGTQQPDGPCRVRYKQRK*

>CYP46a ctg30700 62% to Fugu CYP46 90% to CYP46b two exon 14s out of seq. order
276353 MISEWIFYIILYLLAAVFTAFFAYCLYVHHIHQKYDHIPGPPRD 276222
276114 NFLLGHSPSLTKALYSDDSLIYDLFLQW 276031
274832 AEKYGPVYRINTLHYVTIVVYCPEATK 274752
274005 TIMMSPKYTKDPFVYRRVFNLFGKR 273931
271082 FLGYGLITAVDHDIWYRQRRIMDPAFSSS 270996
       YLRSLISTFDEMSERLMDKLEEIANNKTPAVMHDLVNCVTLDVICK
270501 VAFGVDLNFLTQKDSPFQNAVELCLKGMTFDVRDPLFR
       IIPKNWKLIQQVREATELLRKTGEKWIQNRKTAVKNGEDVPKDILTQILKSAGM
269262 QNVTSTEDFEQMLDNFVTFFMA 269197
268999 GQETTANQLSFAIMELGRNPEIYKR 268925
268842 AKAEVDEVLGTKREISNEDLGKLTYLSQ 268759
268675 VLKETLRLYPTAPGTNRWLHEDMVINGIKIPGGCSVM 268565
268365 FNSFVSQRLEKFFKDPLKFDPKRFDENAPK 268276
296567 PYYTYYPLALGPRTCIGQVFSQ 296502
264748 MEAKVVLAKLLQRFEFSLVPGQSFDIKDTGTLRPKSGVICYIKQCS* 264608

>CYP46a ctg30700 Duplicate exons 12, 13, 15
293940 VLKETLRLYSTAPGTNRWLHEDIVINGIKVPRGCSVM 
       FSSYVSQRLEKFFKDPLKFDPERFDVNAPK 293584
289807 PYYCYYPFSLGPRTCLGQVFAQ 289742 
289356 MEAKLVLAKLLQRFEFSLVPGQSFDIKDNGTLRPKSGVICNIKQCS* 289216

>CYP46 pseudogenes? ctg30700
(-) exon 1
399490 MVSEWVLYIIFYLLSAVFTAFLAYCLYIHHLHQKYD 399383

(+) exons 6, 7, 8
398372 YLRSLISTFDEMSERLMDKLEEIANNKTPAVMHDLVNCVTLDVICK 
       VAFGVDLNLLNQKDSPFQNAIELCLNGMALDARDPLFX 398707
398811 XXPKNWKLIQQIRDAAVLLRKTGEKWIQNRKTAVKNGEDVPKDILTQILKIAGV

>CYP46b BC055161 cDNA 62% to CYP46 fugu 90% to CYP46a 
MVSEWILYIIFYLLSAVFTAFLAYCLYIHHLHQKYDHIPGPPRDNFLLGHSPSLTKA
MYSDDSLIHDLFLQWAEQYGPVYRINTLHYIAIVVHCPEATKTI
LMSPKYAKDPFSYSRLFNLFGKRFLGNGLVTAVDHDIWYRQRRIMDPAFSSSYLRSLI
STFDEMSERLMDKLEEMANNKTPAVMHDLVNCVTLDVICKVAFGVDLNFLTQKDSPFQ
NAIELCLNGMALDARDPLFRIFPKNWKLIQQIRDAAVLLRKTGEKWIQNRKTAVKNGE
DVPKDILTQILKIAEEENVNSSEDLEQMMDNFVTFFIAGQETTANQLSFAIMALGRNP
EIYKRAKAEVDEVLGTKREISNEDLGKLTYLSQVLKETLRLYPTAPGTNRWLHEDMII
NGIKIPGGCSVMFSSFVSQRLEKFFKDPLKFDPERFDENAPKPYYCYYPFALGPRTCL
GQVFSQMEAKVVLAKLLQRFEFSLVPGQSFDIKDTGTLRPKSGVICNIKQCS*

>CYP51A1 AY496939
MTILEVGSQLIESAVLQMSLTSVLLTASVFTLTLGYISKLLFTQ
HSSEHTKYPPHIPSSLPFLGQAVAFGRSPIEFLEKAYEQYGPVVSFTMVGKTFTYLLG
SDAAALMFNSKNEDLNAEDVYARLTTPVFGKGVAYDVPNPLFLEQKKMLKTGLNIAQF
KQHVEIIEEETKDYFRRWGESGERNLFDALSELIILTASRCLHGCEIRSLLDERVAQL
YADLDGGFTHAAWLLPGWLPLPSFRRRDRAHLEIKKIFYNVIKKRREDTEKHDDILQT
LIDATYKDGRPLSDDEIAGMLIGLLLAGQHTSSTTSAWMGFFLARDRALQERCYSEQK
SVCGEELPPLHYDQLKDLSLLDRCLKETLRLRPPIMTMMRMAKTPQKVGEYTIPPGHQ
VCVSPTVNHRLQDTWAERLDFDPDRYLHDNPAAGEKFAYIPFGAGRHRCIGENFAYVQ
IKTIWSTLLRMFDFELVDGHFPPVNYTTMIHTPHNPIIRYTRRNAQPQQ

>bZ14P11 65% to bacterial CYP173A2 Sinorhizobium meliloti (contamination) 
20450 VIQAKFFGQLTTIVNHPGLIRHVLVDNAANYGMQPVRQLVLRPILRDGLLTAEGDTWKR 20626
20627 SRKAMAPVFTPRHARGFANQMLDQSMKFADGMQGSAKVGAEVNVSQEMTELTFAILAETL 20806
20807 FSGEIVRTAGNFAEHVDKLLHTMGRIDPMDLLQAPSFVPRVTRWAGQRPLNHFRRIVAET 20986
20987 MEQRRPRIADGTAPRDFLTLLLELEGPDGLTREEIEDNILTFIGAGHETTARS 21145
21146 LAWTLYLLAEAPHFRAQVEAEVDRVVASGADPVEWLELLPHSRAAFEEAMRLYP 21307
21308 PAPNLGRAPLKDDVWTDENGRRYEMPAGEAVLVMPWVLHRHKLYWENPRQFMPERFLPGN 21487
21488 REKIGRFQYLPFGAGPRICIGATFALQEAVIALAVLLNRFRFETTTNTKPWPV 21646
21647 QRLTVQPLAGLPLR 21688

>CYP2D-like AI497150 fb62g02.y1 C-HELIX REGION new 90% to CYP2
FQMIFFVSLGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKPIDPQHL 207
YHQAAANIIASIIFRSRFDYQD 273

>CYP2 AI658337 fc21h01.y1 fc21h01.x1 new 71% to 2AA1
MLAALLLLDLSSVGLSLFLGLIFLVLFEIFRIHSCKGRFPPGPTPLPFVGSIPHFLNNPMGFI 
KSLSQYGEMTTVYPGRKPAIILNTLQLMKEALVQNGSSFSGRPPVPVFNWVTDGYGIVM 
ATFGHSWRQQRRFALHTLRNFGLGKKSVEERVTEESGYLISEFLXAEGKPFNPQHAI 
550 FNPENFLDDKGHFFKPEAFLPFSLGPRACLGETLAKAELFLFVTSLLQRIRFSWPTGE 377
376 KLPDMNGIFGIVRSPKPFNIICHSRGSKH*

>CYP2 N-TERM COMPLETE TRANSLATION 44% to 2H2 chicken New 69% to 2AA1
MLVGLLKLDLSSVGLSLFLGLFCLALFEICRIRIYKGRYPPGPTPLPFVGTIPHFLKNP
MGFIRSLSQYGEMTTVYLGRKPAIILNALQLMKEAFVQNGSSFSGRPPVPVLTWVNQGY
GIIMAMDGHSWRQQRRFALHTLRNFGLGKKSVEERVTEESGYLICE

>CYP2 Length = 544 121-301 complete translation 41% to 2F4 90% to AI497150 
GKGVIMADYGECWREHRRFAVTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQ 
HLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPL 
PFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVT 

>CYP2K AI882922 fc47c09.y1 65% to 2K1 105-197 C-HELIX REGION near to 2K8
EFGERDITPIFQDCNQGQGIVFANGERWRTMRRFALSTLRDXGMGKKLSEEKIVDETTLS
AGVFMKFEGQPFDTTQPVNYAVXNIISAIVMGT

>AF221128 mRNA, partial cds 77% to 2K8
5   ANIVPLSLPHKTTSDITFNGYFIKKGTTVVPLLTSVLKDESAWEKPNSFYPEHFLDEKGQ 184
185 FVKRDAFIPFSAGRRVCLGESLAR 256

>CYP2M1      Onchorhynchus mykiss (rainbow trout) GenEMBL U16657
MDVLHILQTNFVSIIIGFVVIILLWMNRGKQSNSRLPPGPAPIP
LLGNLLRMDVKAPYKLYMELSKKYGSVFTVWLGSKPVVVISGYQAIKDAFVTQGEEFS
GRANYPVIMTVSKGYGVLVSSGKRSKDLRRFSLMTLKTFGMGRRSIEERVQEEAKMLV
KAFGEYRDSVVNPKELLCNCVGNVICSIVFGHRFENDDPMFQLIQKAVDAYFNVLSSP
IGAMYNMFPRIVWCFPGNHHEMFAIVNKAKVYIQEQAEIRLKTLNISEPQDFIEAFLV
KMLEEKDDPNTEFNNGNMVMTAWSLFAAGTETTSSTLRQSFLMMIKYPHIQESVQKEI
DEVIGSRVPTVDDRVKMPYTDAVIHEVQRYMDLSPTSVPHKVMRDTEFYNYHIPEGTM
VLPLLSSVLVDPKLFKNPDEFDPENFLDENGVFKKNDGFFAFGVGKRACPGEALARVE
LFLFFTSVLQRFTFTGTKPPEEINIEPACSSFGRLPRSYDCYIKLRTEK

>CYP2N2     Fundulus heteroclitus (killifish) AF090435
MWFYNLLLSLDVKGLFLFIFLFLLIADFYKSRKPANFPPGPKAL
PFVGNFFSLDSKHPHVYFQKLAEIYGNVFSFRLGRDSIVFLNGYKAVREALVTQAENF
VDRPFNAITDRFYTEPSAGIFMSNGEKWKKQRRFALSTLRNFGLGKNSLEQSVSEEIQ
HLQEEMEIEKGKPFNPSGLFTNAVSNIICQLVMGKRYDYTDHRFQMMLRCMSEAVLLE
GNVWGQLYMAFPSVMRYMPGPHNKIFSHFSSVEQFLYEEVEQHKKDLDRDNPRDYIDT
FLIEMENHKESDLGFTEANLVYCAIDLFLAGTETTATTLLWALVFLVKYPEVQEKVQA
EIDSVIEQARLPSMADRSSMPYTDAVIHEIQRIGNILPLNGMRVAAKDTTLGGYFIPK
GTSLMPVLTSVLFDKAEWACPDTFNPGHFLDDNGKFVKRDAFLPFSAGKRACIGESLA
KMELFLFLVALLQKFTFSVPEGVELSTEGITGTTRVPHPYKVSAKIR

>CYP2P3      Fundulus heteroclitus (killifish) GenEMBL AF117343
MEAIRSVLGLEWIDARGVLLFFFVFLLLSDVLRNRKPKNFPPGP
LALPFIRDLHRIRPARLHLQLTEFAETYGDIYSLHLFGGRAVIINGYKHVKEALVQKG
EDFMDRPNIPLFADFFNNKGLVMSNGYQWKVQRRFALHTLRNFGLGKKAMERYIQQEC
QYLNEAFSEQQGKPFNGQALINNAVSNIICCLVFGNRYEYNDKQYQTILQYFNEAVRL
QGDLSVQIYNSIPGLMRWLPGSHKKIFMILQKLVDFVEIRIKEHRENLDPSSPRDYID
SFLIEMGEKEDKDSGFELSNLCACTLDLFGAGTETTTTTLHWGLLYMIYYPQIQERVQ
AEIDAVIGPSRQPSVADRENMPYTDAVIHEIQRMGNIIPLNLPRMANKDTTLDKYSIP
KGTIIIPTLHSVLQDKSIWETPQTFNPQHFLDQDGQFRKRDAFMPFSTGKRVCLGEQL
ARMELFLFFTSLLQRFTFSAPAGEEPSLEFKLGATRSPKPYRLCATPR

>CYP2U1 fugu
MMSLSWLQSLSSSILTLVIMIILHHLFKCYQKRHGFANIPPGPKPWPVVGNFGGFL
VPSAIRKRFGSKAEGPAK
NAAAVLTELAKVYGNVYSIYVGSQLVVVLNGYKVVRDALSNHPDVFSDRPDIPAISIMTKRK (1)
GIVFAPYGPLWQKHRRFCLSTLRNFGLGRLGLEPCIVEGLTNIKTELLRLE 
EESGGAGVDPAPVISNAVSNVICSLVLGHRFNHDDQEFRSMLRLMDRGLEICVNSPAVLI 
NVFPLLYHLPFGVFRELRQVERDITAFL
KRFIANHQETLDPNNPRDLTDMYLKEISARREAGDVDSGFTED
YLFYIIGDLFIAGTDTTANSVLWVILYMASYPDIQ (1)
DKVQAEIDGVVGPLRTPSLSDKGKLPFTEAAIMEVQRLTTVVPLAIPHMTSETI (1)
EFMGYTIPKGTVVLPNLWSVHRDPTEWDDPDSFDPTRFLDEDGTLLRKECFIPFGI (1)
GRRVCMGAQLAKMELFLTVTNLLQTFHFRLPEGAPRPPLQGRFGLTLAPCPYTVCINPR

>CYP2X1   Ictalurus punctatus (catfish) GenEMBL AF315346.1
MLGSWLLVVFCVCLLFLFIRIQRPKNFPPGPRPIPIFGNLFQFN
IKNPLKDFEKLAEQYGNICSLYIGTKPAVVLNGLKVIREALVTKSADFSGRPQNMLKD
VTEGKGIVIADYGRQWKEHRRFALMTLRNFGLGKQSMENRILGEIEHLVAKLEKYAGS
SMYPQTLFHDAASNIIYLVLFGTRYDYGDETLKVYVRLYSENAKLANGTWSIIYDALP
ILRSLPLPFKKAFDNYSTLKILTANMINKHRTTRVPGKPRDLVDCYLDEIDKKDNEST
FSEEQLVVYIMNLHIAGTDTTSNTLLTSILYLMAHPDIQKRCQKEIDVVLEGNSQPSF
EDRHNMPYTQAVVHECQRIARTVPLSVFHCTTRDTELMGYTIPKGTMIIPNLSSVLSE
EGQWKFPHDFNPSNFLNEQGQFEKPEAFIPFSAGPRVCLGEGLARMELFLFLVTLLRR
FQFIWPEDAGEPDFTPIFGLTLTPKPYRMGVKLRQPAREK

> zfishC-a953b08.p1c Length = 570 13-93 66% to 2X1
 zfishG-a1843b03.p1cLength = 594 13-53
256 SSVLVLICILLVFLLIRIQRPKNFPPGPSPLPIFGNLLHFNLANPLK 396
471 HFKFAEKYGNIFSLYTGSRPAVFLNSFAVIKEA 569

> zfishI-a36g12.q1c Length = 590 9-59 58% to 2X1
263 TMLTALVLLCLGAFLLYLQVRIRRPKDFPPGPAPVPFFGNLLQLNRINPIK 111

> zfishG-a2651b11.q1c Length = 706 119-165 46% to 2C18 72% to 2X1
522 VLADYGPLWKDHGRFALMTLRNFGLGKQFMVDRILGEIAHVVGGLGK 662

>CYP2 AI496898 fb63f09.x1 70% to 2X1
486 GTIIIPYXSSSLREESQWKFPHEFNPQNFLNEKGKFVKNDAFMPFSAGPRVCLGENLARM 307
306 ELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPR 169

>CYP2 AI723168 fc33e01.x1 39% TO 2D18 50% to 2X1
PATFLYRRGPFEKPRAFYPFSPGPWVGLGKSLAPKDLFFIFAPLFGGFPFVWPQKAGKP 50
NFPPVFGVPLPPHP 8

>CYP2 AI883438 fc64b09.y1 n-term 45% to 2C sequences
MFGALVKLDLSSVGLTLLLGLILLVLFEIFRIHSYKSRFPPGPTPLPFVGNLPHLLRDPMGFN
RLMAQYGEMSTMYLGKKPAIVLNTIQVAKEALVQEAFAGRPCLPAIDWTSNGC
GIIMATFNNSWKQQRRFALHTLRNXGLGKKSIESRVLEESQYL top = 2AA2 bottom new 2AA seq
TPLVDXITRFAETVPSGVFHEXIWATKLRGFDIPQXTMIMTNLXAISAVK
DHXKHPDTLNPENFLDENGHFSKPESYIPFSLRLRACIGESLVRTELFLFA
TVLLQRIHFSWPPDAKPIDMDGIVGIVRYPQTFSIICCSRDSKK*

> zfishC-a1785a09.p1c Length = 700 12-65 86% to 2AA1
395 LTLFLGLIFLVVFEISRIYSYKCRFPPGPTPLPFVGNLPHLLKKPMEFIRSVS 553

>CYP2 AI497151 fb62g03.y1 WashU MPIMG EST 56% to 2N2
MAYTAMLETLDVKGILLFMVAFLLVADYLKNKNPPKYPPSPFSVPLLGNIFNVDSKEPHLYLTKLGHA 206
YNNIFSLRLGSDKTVFITGYKMVKEALVTQAENFVDRPNSPVLARVYSGNAGLFFSNGEM 386
WKKQRRFALSTLRNFGLGKKTMELAICEESR 473

>CYP2 AI545376 fb74e03.y1 85% to 2V1
MALENILLHLTSKVWTDAVTILLMVILFLLVSVKLRNRNKPHKNLPPGP
TPLPFIGDVFNLDTSQPHIDLT*MSDHYGNIFS

>CYP2 AI544925 fb69d04.y1 54% to 2F1 85% to 2Y3
RWRRKENGLSLPPVPLALPLIGNLLTLDKSAPFKSFMKWRKTYGSVMTVHLGPQRMVVLVGYETVKEALV
DQADDFAPRAPIPFMNRIVKGYGLAISNGEGWRQXXXFTSPHLGDFGVGRNRLEQWIQXEIRYLL*SFEK

>CYP2 AI958763 fc96g05.y1 1 diff with 2a5 or 2a12
GKLPPGPTPLPFIGNY

>CYP3A top half = 3C1 bottom = 3A65
MFDLSSLSVTWTLVVLVITLLLIYGVWPHGFFKKLGIPGPRPLPFVGTALSYSKGICNFDIECSKKYGK
VWGIYDGRLPLLLVTDLEMIKTILVKDCYSTFTNRRNMNPDLVGPFADGITLVKDERWR 447
RIRSSLSPSFTCGRLKEMFGIMNKHSHILVDSMGKTAKRGESADIKEFFGAYSMDVVTST 181
AFSVDIDSLNNPKDPFVTNIKKMLKFDLLNPLFLLIAFFPFMAPVLEKMDFALFPTSVTD 361
FFYAALQKIKSDRDTKTLAKDNTKKRVDXLQLMVDSQTGXXXXXXXXXXXX 478
GMRFALMMMKLPVGKLLQKYPVETCKKTQIPGQLNFFFQPKVPLPLKLIPRSPKEKQ*

>BG727940 fo79h04.y1 CYP3A 61% to 3A65
289 LSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDT 348
349 VLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWT 408
409 EPEKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCK 468
469 ETQIPLKLSLGGLLQPEKPVVLKVESR 495

> AW018919 fd61g06.y1 CYP3A 5 aa diffs to 3A65
  1 YNLATNPETMKKLQEESDETFPNQAPVDYETLMSYYYLDAALSESLRLYPVAARLERVCK 180
181 KTVEINGLLIPKDLVVMVPTYALHRDPDYWSEPESFKPERFTKGNKESIDPYMYMPFGLG 360
361 PRNCIGMRFAQLTMKLAIVEILQRFDVSACDETQVPLELXFNGLLSPKDPIKLKLQPR 534

>AW202769 fj22a02.y1 CYP3A AW232617 fj22a02.x1 top half = 3C1
 91 MCDLSSLSVTWTLVVLVITLLLIYGVWPHGFFKKLGIPGPRPLPFVGTALSYSKGICNFDIE 267
268 CSKKYGKVWGIYDGRLPLLLVTDLEMIKTILVKDCYSTFTNRRNMNPDLVGPFADGITLV 447
448 KDERWRRIRSSLSPYFTSGRLKEIFPIAMTHADRFIENMEKKDPNLPLKIEDVVAPYSL 624
625 DVVRSSSFSVDYDYIDNPDDTLVTSHKSLYNINP 726
LDMAIHESMRVFPAGPRLERVCTKPVEIHGITHTKTTLIGIPLYV
ISRDPDLWESPNEFKPERFSPESETEINQCPFMPFELGPRNCIGMRFALMMMKLLVVKLLHKY
TVETCKETQIPVQLNFFFQPKVPITLKLIPRSHKEKQ*

>CYP3A AI883503 fc65a12.y1 like 3A27 opposite end = AI878727 95% to 3C1
IYDGRLPILMVTDLEMIKTIMVKECYSTFTNRR
TRPAFCPSAANFLAKMGISLFSRSTTDFYYKALRKIKDEHNESN 134
GRVDFLKLMIQNQIPDDQVKDTASEQPVKGLTDHEILSQSFIFILGGYETTSTTLSYLLYN 427
LATNXXXXXKLVEEIDKNFPLDIPITYDALMRMDYLEM 537
LDMAIHESMRVFPAGPRLERVCTKPVEIHGITHTKTTLIGIPLYV
ISRDPDLWESPNEFKPERFSPESETEINQCPFMPFELGPRNCIGMRFALMMMKLLVVKLLHKY
TVETCKETQIPVQLNFFFQPKVPITLKLIPRSHKEKQ*

>CYP3A27 trout U96077
MMSFLPYFSAETWTLLALLITLIVVYGYWPYGVFTKMGIPGPKP
LPYFGTMLEYKKGFTNFDTECFQKYGRIWGIYDGRQPVLCIMDKSMIKTVLIKECYNI
FTNRRNFHLNGELFDALSVAEDDTWRRIRSVLSPSFTSGRLKEMFGIMKQHSSTLLSG
MKKQADKDQTIEVKEFFGPYSMDVVTSTAFSVDIDSLNNPSDPFVSNVKKMLKFDLFN
PLFLLVALFPFTGPILEKMKFSFFPTAVTDFFYASLAKIKSGRDTGNSTNRVDFLQLM
IDSQKGSDTKTGEEQTKGLTDHEILSQAMIFIFAGYETSSSTMSFLAYNLATNHHVMT
KLQEEIDTVFPNKAPIQYEALMQMDYLDCVLNESLRLYPIAPRLERVAKKTVEINGIV
IPKDCIVLVPTWTLHRDPEIWSDPEEFKPERFSKENKESIDPYTYMPFGAGPRNCIGM
RFALIMIKLAMVEILQSF TFSVCDETEIPLEMDNQGLLMPKRPIKLRLEARRNTPSNT
TATTLKSPTT

>BF938740 36% to CYP5A possible pseudogene of CYP5A
C*WTCLKWFGVEASGLSLTVCLFLLFLSLLYCYSISPFSNLKQYNIKHPNPLPFIRNLIIFQNHF 264
FXSHTNLINKYGLIYIYYIGPLSTVIIIYPNIL 363

>CYP7A BG884003 fp29f09.y1 33-199 new 45% to 7A
 68 *LCGYAVTXRKRKPGEPPLVTGWLPFIGVTKDYVANPLGFLTETQKKHGNVFTCLIAGKYF 247
248 TFVTDPFSFSSVVRQGKNLDFQKFAINFSQRVFGHADFNSPQLSGNYREIHSIFRQT 418
419 LQGPSLQHLTQSMLCNLQTVLERCLPHEHDWLEEGLQSFTNRIMFEAGFLTLFGKE 583

>CYP7 BG883457 fp29f09.x1 381-502 54% to 7A
534 IKKEDYIALYPQLLHLDPEIYPNPTEFKYNRFLDENDQPKTNFFKSGRRLRNFLMPFGSG 355
354 ASECPGRFFAVYEIKLFLALTLWHYDLQLRDPDVPVVQDSARAGLGIMPPSQDVLLRFR 178
177 KK 172

>CYP11A1     Oncorhynchus mykiss (rainbow trout)GenEMBL S57305 
MMVSWSVCRSSLALPACGLPSARHNSSMPVVRQALSPDNSSTVQ
NFSEIPGLWRNGLANLYSFWKLDGFRNIHRVMVHNFNTFGPIYREKIGYYDSVNIIKP
EMPAILFKAEGHYPKRLTVEAWTSYRDYRNRKYGVLLKNGEDWRSNRVILNREVISPK
VLGNFVPLLDEVGQDFVARVHKKIERSGQDKWTTDLSQELFKYALESVGSVLYGERLG
LMLDYINPEAQHFIDCISLMFKTTSPMLYIPPAMLRRVGAKIWRDHVEAWDGIFNQAD
RCIQNIYRTMRQDTNTHGKYPGVLASLLMLDKLSIEDIKASVTELMAGGVDTTSITLL
WTLYELARHPDLQEELRAEVAVARQSTQGDMLQMLKMIPLVKGALKETLRLHPVAVSL
QRYITEEIVIQNYHIPCGTLVQLGLYAMGRDPDVFPRPEKYLPSRWLRTENQYFRSLG
FGFGPRQCLGRRIAETEMQLFLIHMLENFRVDKQRQVEVHSTFELILLPEKPILLTLK
PLKSGQ

>CYP11 zfishB-a659e05.p1c zfishG-a1981b11.q1c zfishG-a1983f12.p1c
88 REKVGFYESVNIIKPEDAAILFKAEGHYPKRLTIDAWTAYMDYRNRKYGVL 138
211 VLYGERLGLLLDNIDPEFQHFIDCVSVMFKTTSPMLYLPPGLLRSIRSNIWKNHVEAWDGIFNQ
275 ADRCIPEYLSNIGKKIQKHGKVPGVLA 301
329 TAITLLWTLYELARNPDLQEEIRAEISAARIASKGDMVQMLKMIPLVKGTLKETLR 384

>CYP17 Oryzias latipes (medaka) GenEMBL D87121(2421bp)
MAWFLCLSVLVVLVLALAALLWRVRTRDRPQEAPSLPYLPVLGS
LLSLRSPHPPHVLFKELQQKYGQTYSLKMGSHQVIIVNHHAHAREVLLKRGRTFAGRP
RTVTTDVLTRDGKDIAFGDYSATWRFHRKIVHGALCMFGEGSASLQRIICTEAQSLCS
TLSEAAATGLALDLSPELTRAVTNVICSLCFNSSYSRGDPEFEAMLRYSQGIVDTVAK
DSLVDIFPWLQIFPNKDLRLLKQCVAVRDQLLQKKFEEHKSDYSDHVQRDLLDALLRA
KRSAENNNTAAEFSAEAVGLSDDHLLMTVGDIFGAGVETTTTVLKWAITYLIHYPEVQ
KQIQEELDRKVGVDRPPQLSDRGSLPFLEATIREVLRIRPVAPLLIPHVALSDTSLGD
FTVRKGTRVVINLWSLHHDEKEWTNPDLFNPGRFLSADGSSLTLPSSSYLPFGAGLRV
CLGEALAKMELFLFLSWILQRFTLSVPPSQSLPSLEGKFGVVLQPVKYAVKATPRPGC
HSGLFPANP

>CYP? AI617721 zehn2020.seq.F 34% TO 2J3 MID 30% RANGE WITH MANY FAMILIES, 
GIEIKKGTIVAPFAISIQRNPTIYKDPHTYNPERWLTNDNNTK*MDSFSFIPFSAG*RTC 182
IG*HLA*LEARIILNLFVKNFEFSCP 260

>zfishG-a1026b07.q1c Length = 601 278-387 49% to 2J2 57% to 2N2
121 IITKKNDTEAGFTVGSLEWSMVDLFEGGTETTTNSLRWALLFLIKYPDIQ
    QKVQAEIDEVIGSRLPSMSDKANMH 480
481 YLNAFIHEVLTRANLVPLNMARVAKKDTTLGGYFI 585

>zfishB-a619a12.q1c Length = 738 328-437 77% to 2K8
134 DRVQEEIDRVIGGRQPAVEDRKKLPYTYAVIHEIQRFANIVPLNLPHTTSCDITFNGYFI 313
530 GTTVIPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVKRDAFMPFSAG 673

>zfishC-a628g07.p1c Length = 570 305-394 84% to 2p10
52  GPETTSTTLYWGLLYMMKYPEIQ
    SKVQQEIDAIVGGSRQPSVSDRDNMPYTNAVIHEIQ 311
312 RMGNIIPINLARTTSEDTQIEKYSIPKVGIVV 407

>zfishC-a25h04.p1c Length = 635 304-374 70% to 2K8
490 AGNDTTGSALRWGLMLMAKYPQIQDRVPE*ID 311
310 RVIGVRHPVV*GRKKLPYADVVIHKIQRLANIVPMNIPH 194

>zfishC-a603d07.p1c Length = 580 60-118 50% to 2X1
96  VFLQFAPHYGSIYGIYIGSKPAVVLTGQKMIKEALITQAAEFAGRPNHMMISHITRSEG 272

>zfishG-a1551g08.q1c Length = 567 318-389 61% to 2AD3
24  LIRARYPEMNIFCVFVFSEKVQSEIDQVIGQTRQPLMDDRTNLPYTYAVIHEIQRFANIV 203
204 TFTPPRVANKDTTVGGQLIPK 266

>zfishC-a250a11.q1c Length = 574 62-118 51% to 2AD3
113 LQLIEKYGNIFSVRIGSDKIVYVSGFKMVKDVLITQGENFTDRPVSPLFDTLYKGRG 283

>zfishK-a181a04.p1c Length = 637 328-394 48% to 2X1
286 EQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKVTFTV 83

>zfishG-a1551g08.p1c Length = 611 375-438 45% to 2N2
586 KIHKSNTSQSVWLLQGVIVLPMLKPILLDKKEYSTPYDFNPDHFLDQNGKFLKKENFIPFSIGK 395

>zfishC-a1699d01.q1c Length = 707 289-345 80% to 2K8
462 FHEENLMLTVANLFAAGTDTTGTTLRWGLMLMAKYPHIQ
    DRVQEEIDRVIGGRQPVV 707

>zfishG-a606c02.p1c Length = 595 233-327 78% to 2AA1
524 FPGPHQKIKQNANELLAFIQGEVKEHKKTLDPDSPRDFIDAYLLE
    LKQQKSNKDSTFHEGNLAISTADLFLAGTHTTSTTIRWGLLFLTQNPDVQ 138

>zfishG-a1901c03.p1c Length = 622 325-388 83% to 2AA2
260 HNTERCHKEIVQVLGYDRLPSMEDRDRLPYTLATVHEIQRCANLAPFGLIHETIQPTKLQGYDLP 66

>Z35723-a339f11.p1c Length = 731 325-388 83% to 2AA2
320 HNTERCHKEIVQVLGYDRLPSMEDRDRLPYTLATVHEIQRCANLAPFGLIHETIQPTKLQGYDLP 126

>zfishC-a678c11.p1c Length = 594 116-207 67% to 2K8
503 GSGILFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFEGT
    PFDTTQPVK*DVSNIISSIVYGSRFEYTDPQFTEMVDRA 147

>zfishG-a899b03.p1c Length = 622 222-327 41% to 2N2
578 IYEAFPAIMKHLPGPHNDIFSNYDLLKSFVHEVIVKHKAKLDPSEPRDYIDTFLIEMKEV 399
398 K*CLNDRRSLFN 363
292 TALRNQTLLHVFLTCLRQGTESTSNTLCWGLIYLIMYPDVQ 170

>zfishC-a1646d09.q1c Length = 573 389-437 75% to 2X1
318 KGTIIIPYLSSSLREESQWKFPHEFNPQNFLNEKGEFVKNEAFMPFSAG 464

>zfishB-a33e04.q1c Length = 674 222-323 73% to 2AA2
420 IFNLAPFIKHFPGPHQKIKKNSNELYSFIEDEVEEHRKTLDPVSPRDFIDAYLLE
    LKQQKSNKDSTFQEENLIGSAIDLFFAGTDSTATSIRWGLLFLFRY 34

>zfishC-a2848h06.p1c Length = 703 233-327 73% to 2AA2
510 FPGPHQKIKKNSNELYSFIEDEVEEHRKTVDPVSPRDFIDAYLLE
LKQQKSNKDSTFQEENLIGSAIDLLFAGTDSTATSIRWGLLFLIQNPDVQ

>zfishB-a46b05.q1c Length = 718 222-322 73% to 2AA2
429 IFNLAPFIKHFPGPHQKIKKNSNELYSFIEDEVEEHRKTLDPVSPRDFIDAYLLE
    LKQQKSNKDSTFQEENLIGSAIDLFFAGTDSTATSI 73
72  RWGLLFLIR 46

>zfishC-a402h10.p1c Length = 598 226-327 74% to 2AA2
199 FAPIIKHFPGPHQKIKRNADELSGFFQHEVKEHKKTLDPGSPRDYIDAYLLEM
    KQQKSNKDSTFHDENLIGSTTDLFVAGSDSTATTFRWG 558
559 LLXLIQNPDVQ 591

>zfishC-a1468a05.q1c Length = 729 63-118 88% to 2K8
322 QLSKKYGPVFKVHLRRKKVVVLAGYKTVKQALVNQAQEFGERDITPIFHDCYHGQG 489

>zfishC-a1101c09.q1c Length = 578 289-327 82% to 2K8
436 FHEENLMLTVANLFAAGTDTTGTTLRWGLMLMAKYPHIQ 552

>Z35723-a848d07.q1c Length = 735 18-108 39% to 2X1
258 FLCVLLLVKHFRDVYSKNMPPGPFPLPFVGNLTNIGFSDPLGSFQRVS 401
589 LVCQIAEKYGDVCTLYLXTKPCILMTGYDTLKEAFVEQADIFTDRPYFP 735

>zfishC-a440h04.p1c Length = 730 226-322 73% to 2AA2
193 FAPIIKHFPGPHQKIKKNADELSGFFQHEVKEHKKTLDPGSPRDYIDAYLLEM
    KQQKSNKDSTFHDENLIGSTTDLFVAGSDSTATTFRWGLLFLYK 570

>zfishG-a2684h06.p1c Length = 751 116-277 52% to 2K8
715 GSGISFPKAQSWKDMPRFAISNLADFGMGKRGSEETIIEEIHHLKAEFDKFEGT
    PFDTTQPVNYAVSNIISSIVYGSRFEYTDPRFTE 356
355 MVDRAINVLMHIFLCMYFRIYNIFPWLGLFLN 179
178 SKRTVVRNMLKNRAEFMKLITGLQETLNIHDRRGFVDSFLIR 53

> zfishG-a835b06.p1c Length = 602 432-471 73% to 2AA1
516 FSFSPGPRACLGETLAKVELFLLVTSLLQRIRFSWPTGEKLPD 388

> zfishK-a1004a03.p1c Length = 536 437-465 89% to 2K6
228 GRRVCLGESLARMELFLFFTSLLQSYRFT 142

> zfishC-a2474d08.p1c Length = 714 1-65 70% to 2p10
407 MDLLHIYEWIDIKAVLFFACVFLLLSNYIQNKTPKNFPPGPWPLPIIGNLYHIDFNKIHLEVEKK 213

> Z35723-a834b06.q1c Length = 695 437-476 64% to 2P3
469 GKRVCLGEQIARIELFLFFVSLFRKFRFSATEGEKLNMD 353

> zfishC-a2756d10.q1c Length = 605 437-476 64% to 2P3
60  GKRVCLGEQIARIELFLFFVSLFRKFRFSATEGEKLNMD 176

> zfishC-a2378h05.q1c Length = 724 282-327 50% to 2X1
242 KSDHRTSFDESQMVTLLFDLFIAGTETTFNTLRTLTLYLMTYTHIQ 379

> zfishB-a130g09.q1c Length = 698 119-160 80% to 2AA3
328 VLATFGHSWRQQRRFALHTLRNFGLGKKSVEERVTEESGYLV 203

> zfishC-a463g12.q1c Length = 605 325-383 67% to 2AA2
144 HITERCHKEIVQVLGYDRSPSMEDRDRLLFTLFFVHEIHLCSNLAPLGLIHETIYPTKLQ 323

> zfishG-a789f12.p1c Length = 593 343-434 very similar to 2p10 with del.
470 PSVSDRDNMPYTNSVIHEIQSIGNIGPLNV 381
252 KGTLVIGSLTSVLFDESEWETPHSFNPGHFLDAEGKFRRRDAFLPF 115

> zfishC-a2052h02.p1c Length = 719 119-160 90% to 2AA3
350 VMVTFNHSWRQQRRFALHTLRNFGLGRKSVESRVLEESQYLI 225

> Z35723-a384f04.q1c Length = 685 328-372 50% to 2X1
210 EQCQREIDEVLGARDHVTYEDRNDMHFVQAVIHEGQRVADIVPLNV 73

> zfishK-a149h03.q1c Length = 578 118-180 3 aa diffs with 2AA2
134 GIIMATFNNSWKQQRRFALHTLRNFGLGKKSIESRVLEESQYLFAELLKDEGMTCSC 304

> zfishK-a102g06.q1c Length = 587 163-208 67% to zfishK-a583c07.p1c 65% to 2p9
361 FLPFLGAAFDPTILLYNAVSNIICQMVFGQRFDYADHQFKTMLKYI 498

> zfishC-a2904a10.p1c Length = 721 284-327 60% to 2N2
574 DKEAEFTEENLIHCVLDLFGAGTESTAKTLVWALLYMAKYPDVQ 443

> zfishG-a2826f10.q1c Length = 609 390-417 64% to 2M1
410 GTVVFPL*SSVLIDPKMWKNSNCIDPEN 327

> zfishC-a961a08.q1c Length = 576 437-465 3 aa diffs to 2AA1
88  GPRSCLGETLAKTELFLFITSLLQRIRFS 174

> Z35723-a873a04.p1c Length = 726 6-68 48% to 2N2
257 ILETLDVKGILLFMVAFLLVADYLKNRNPPKYPPSPFSVPLLGNIFNVDSKEPHLYLTKVSR*Y 66

> zfishG-a147a09.q1c Length = 556 118-170 49% to 2p9 
301 GLIFSGGHMCRQQRRFALATLKYFGVGKKTLENSILQECRSVCESVQSERGTV 459

> zfishG-a1901c03.q1c Length = 625 60-160 72% to 2AA1
57  LFSKQLSQYGEMTTIYLGRKPTIMLNTVQLAKEVLIQDAFAGKPSLPVLDWVSNGLG 227
465 VMVTFNHSWRQQRRFALHTLRNXGLGRKSVESRVLEESQYLI 590

> zfishG-a661a12.p1c Length = 607 171-220 78% to 2AA3
310 MSPHHPIQNAVSNIICSIVFGDRFDYDNKRFEYLLELLNENFVLTGSAAG 161

> zfishG-a661c12.p1c Length = 613 171-220 78% to 2AA3
316 MSPHHPIQNAVSNIICSIVFGDRFDYDNKRFEYLLELLNENFVLTGSAAG 167

> zfishB-a496h01.q1c Length = 748 171-220 74% to 2AA1
565 VNPHHALQNAVSNIFCSIMFGERFDYDNKRLGYLLKILNENMMLTGSAIG 416

> Z35723-a508e08.p1c Length = 724 216-325 42% to 2X1
19  SSLVLQLYEIAPVLRIFPLPFWKAFHYFEKITRHSLKVVEEHKKSFVAGEPKDLIDCYL 195
196 EEMKKVRADQRTTFDEAQMVTLLFDLFLAGTETT 375
376 SNTLRTLTLFDDSYSY 423

> zfishC-a2901c10.p1c Length = 723 222-278 83% to 2AA3 
397 IFNLAPFIKHFPGPHQKIKKNSNELYSFIEDEVEEHRKTLDPVSPRDFIDAYLLEI 230

> zfishC-a643a08.p1c Length = 721 12-66 83% to 2K7
272 VSTILAFLLLFLVISYFFSSKDKGKYPPGPKPLPVLGNLHILDLKNTYMSLWKVRK 105

> zfishK-a102g06.q1c Length = 587 163-208 65% to 2p9
361 FLPFLGAAFDPTILLYNAVSNIICQMVFGQRFDYADHQFKTMLKYI 498