Phylogentic trees of selected P450 groups

What's New Jan. 2, 2002

There is a tree with 60 human 47 Fugu and 8 other fish sequences.

What's New Jan. 19, 2000

I have posted a 4 family tree with 89 sequences, including the new Drosophila sequences in the 4 family and in the 18 clan. New 4 Family tree A second tree covering the remaining sequences including the 6, 9, 12 and 28 families is also here New 6 and 9 Family tree This page holds phylogenetic trees of P450s from different groups of sequences.

lllThis image is a phylogenetic tree of 43 sequences.

They are single members of subfamilies from the top half of the P450 tree.

The sequences are from top to bottom: 2C9, 2H1,2E1,2F1,2G1rat,2A6,2Q1

2B6,2M1,2N1,2P1,2Jer1,2D6,2K1,2L1,18,1A1trout,1A1human1,1A2chick,

1B1human,17,21,71A1,71C1,71B1,83,84,76A1,76B1,75A1,80,

82,73A1,81A2,78A1,79,77A2,89,85,90,87,88 and 86A1

Note: The last five sequences naturally fall in the lowerhalf of the tree.

They are included here, because they are plant sequences. See the single

family member tree for a more accurate placement of these sequences.

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This image is a phylogenetic tree of 57 sequences.

They are single members of subfamilies from the bottom half of the P450 tree.

The sequences are from top to bottom: 13,3A3,4H1,5A1,9C1,15,9B1,9A1,6A1,

6C1,6B1,6D1,4A11,4B1,4F2,4L1,4K1,4D1,4E1,4C1,4M1,4J1,4G1,4P1,102,

118,110,72A1,24,4N1,27,10,11A1,11B1,12,52A1,52D1,52B1,52E1,52C1,

14A1,53,57A1,60A1,60B1,62,58,56,59,19,61,51,8,7A,7B,54,74

Note: This tree does not include the 85, 86, 87, 88, and 90 plant families that were

included in the upper half of the tree.See the single family member tree for a more

accurate placement of these sequences.

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This image is a phylogenetic tree of 55 sequences.

They represent single members of P450 families, not including the bacterial

cam-like sequences.

The sequences are from top to bottom: 2C9,18,1A1,17,21,14,71A1,84,83,75A1,

76A2,80,82,73A1,81A1,78A1,79,77A2,89,13,3A3,5A1,6A1,15,9A1,

4A11,102,118,52A1,110,72A1,56,24,27,10,11A1,12,85,90,87,88,53,57A1,

60A1,62,58,59,86A1,19,61,51,54,7A,8,74.

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This image is a phylogenetic tree of 30 bacterial cam-like

P450s. The CYP102, CYP110 and CYP118 (Eukaryote-like) are not included.

The sequences are from top top bottom: 105A1,105D,105B,105A2,55A1,55A2,

55A3,105C,105E,107G,107D,107E,107F,107A,107B,107C,112,114,113A,

113B,106A1,106A2,109,111,108,101,116,103,104,117.

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