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April 11, 2000


The Plant P450 Database has exceeded 500 sequence entries. The database has
been updated to include the latest information on which sequences are still
confidential and which have become public. Many new sequences have been added
since the last revision in August 99. Please note that slightly more than half
of these sequences are from Arabidopsis. A large collection of isoflavone
synthases was deposited in Feb. 2000. These can be found in the 93C subfamily.
For a collection of 28 93C accession numbers and their sequences click here

According to the latest Nature of April 6, Monsanto has sequenced all 12
chromosomes of rice to around 5X coverage and will release it to the
International Rice Genome Sequence Project (IRGSP) no strings attached.
The IRGSP will combine this new data with their own and release it to public
databases. The exact time table for this release is not given. For a news item
from the IRGSP click here
The gist of this article is that transfer of the data from Monsanto will be in
May and June and this will accelerate completion of the genome, but it still
might take 3 years. The raw Monsanto data will not go right into public
databases. It seems that only finished segments of the genome will be released.
What would Craig Venter do with a 5X coverage genome? See below.

On April 7 before a congressional hearing J. Craig Venter said Celera was
through sequencing human DNA and would switch to mouse. He said they would
begin assembling the human genome from the present sequence data that they had
accumulated so far and the finished sequence would be ready in 3-6 weeks.
Francis Collins disputed this claim saying it was not possible. Celeras stock
fell 20% in one day after Collins remarks.