The Drosophila P450s have been found in Genbank by systematic BLAST searches of the nr, month, others ESTs, gss and htgs sections, using different P450 family representatives. The first search with Cyp4d2 yielded 101 new ESTs, 6 new sequences from month, one from htgs and none from gss or nr. The second search with Cyp6d2 only found 17 new ESTs and one sequence from month. The third search hit only 5 new ESTs and one sequence from nr. At this point the search was halted, since the returns were not worth the effort of scanning the output for new sequences. Some of the new sequences are very different from other P450s (AC005130) and cannot be easily assembled into a complete sequence by comparison with known P450s. I have identified exon containing ORFS from this gene, but I cannot detect the exon boundaries. If you are brave have a try at it. The new sequences (almost 300 total in the original FASTA file) have been compared with each other by repetitive Do-It-Yourself WU-BLASTs and condensed onto 98 contigs. Ten of these are from other Drosophila species, 88 are from D. melanogaster. Based on C. elegans 80 P450 genes, these 88 genes and gene fragments may represent nearly all the P450s from Drosophila, though some are probably N- and C- terminals of the same gene and the number of contigs will drop as the genome is completed.