Lower Eukaryote P450 Links

Note: After naming 382 P450s from N. crassa, M. grisea, F. graminearum and A. nidulans, there are 13 P450 families in common to all four species. CYP51, 53, 61, 65, 68, 505, 531, 532, 537, 539, 540, 548, and 552. (March 18, 2004) The white rot fungus has 167 P450 sequences and probably near 150 are complete full length P450s. So far 103 have been assembled and 92 are full length P450s. More will come later. Cyp51 has been found and assembled from Trypanosoma brucei (African sleeping sickness) And a partial cyp51 from Leishmania major is also found. These are kinetoplastids and they are far down on the eukaryote tree of life, making these P450s anciently diverging specimens.