After much effort, I have pieced together 71 cytochrome P450 protein sequences starting from C. elegans genomic sequences. Some have been in the GenBank database for some time. Many others are unfinished cosmid sequences in the ftp repositories at the Sanger Center and the Wash U. Genome Sequencing Center. These later sequences were downloaded and… Read More
In looking for new bacterial P450s I found 19 P450s that are new to the alignment. Mycobacterium tuberculosis has at least eleven P450 genes, a bacterial record. One shows some similarity to CYP51 (34% identity) and one must wonder if it has a similar function.
I have started assembling a Rogue’s Gallery (and email directory) of P450 researchers. As of August 28, 1996 there are 231 entries (and 47 pictures). If you dare to be seen in such a collection, send me your picture and any comment you might want to appear with it. You can compress a .gif file… Read More
I have just analyzed 163 Arabidopsis expressed sequence tags found in the ESTdb. These have all been translated and aligned with the other plant P450s in a new plant only alignment of 125 public sequences. 39 confidential sequences have been removed from a comprehensive 165 plant sequence alignment. Some interesting features are noted. A CYP72… Read More