What's New

An estimate has been made for the number of P450 genes in Arabidopsis (372) see P450s sorted by family.

Nine new Arabidopsis P450s have been named 71A16, 79F1, 79F2, 705A5 (now complete), 705A10P, 705A11P, 705A12, 707A3 and 708A2.

Rat UNIGENE entries have now been included as a separate file to complement the mouse and human files.

Lists have been compiled of all the human and mouse P450s in the UNIGENE database. These do not include all pseudogenes, but most of the normal genes are present. The human UNIGENE is much more complete than mouse, with only 3 of 48 human genes not having a UNIGENE entry. click on the mouse and… Read More

I have decided to make a data giveaway on human P450s lying undiscovered in the EST database. I did a search for these in 1995 and have been sitting on them for several years. About half are now cloned, but half are not. So here they are! New human P450s enjoy.

I have begun a housekeeping reorganization of the P450 homepage. It has grown to the point of becoming cluttered and hard to use. To make access to desired sections easier, I have added buttons to link to different subsections of the site. The new homepage also has a name https://drnelson.uthsc.edu/CytochromeP450.html that is easier for search… Read More

All rice P450 fragments in the EST and GSS databases have been found, translated and sorted according to their best matches to other P450s. There are 134 of these fragments. Rice Cytochrome P450s

Plant P450s have been updated and the Plant Cytochrome P450 Database has been completed. All the files have been made so the hyperlinks work. Public and Confidential sequence lists are available for each subfamily. The total count for plant P450s is now 289. This does not count all the ESTs and fragments produced from the… Read More

I have just finished an analysis if Arabidopsis P450s and estimate there are a minimum of 137 P450 genes in Arabidopsis. All ESTs are translated and genes assembled from genomic sequence. See Cytochrome P450 Arabidopsis Links

An alignment of 60 of the 80 C. elegans P450s is posted, along with 45 other sequences from many other families. The 20 C. elegans sequences that are not included in the alignment are either pseudogenes (CYP13A9P, CYP25A6P, CYP33C10P, CYP33E3P CYP35D2P, or they are very similar to sequences in the alignment, such as the CYP13A2-CYP13A8,… Read More