What's New

A note on Plant P450 evolution new ESTs from pine are clarifying how old some plant P450 families are.

The diversity of plant P450s has been displayed in a new table that lists plant higher level taxonomic groups and shows which groups have known P450 sequences. The more than 400 plant P450s belong to 65 species. These include 3 conifers and 62 angiosperms. Ten species of monocots have known P450 sequences. Seven of these… Read More

The plant P450 database has been updated (see the Databases button on the home page). Plants now have over 400known P450s. 212 are from Arabidopsis. The Deep Green meeting in St. Louis described in todays Science has found that plants should be split into three kingdoms not just one. Green, brown and red plants split… Read More

A press release of July 28 from Celera stated that one million sequences (500 million bp of sequence ) have been completed from the Drosophila genome. Below is a quote from the press release. “Celera expects to complete the random sequencing phase of Drosophila in early September when it will begin sequencing the human genome.… Read More

Celera Genomics will finish the Drosophila genome in August or September according to an NPR interview with Craig Venter that aired on July 27. It was not mentioned when the sequence data will be posted to Genbank. The rice P450 page has been updated. There are some new ESTs and some contigs have been joined

A tree with 30 plant P450s coving the CYP93, 705, 706 and 712 families has been posted under the trees button on the home page. The CYP93D1 and CYP712A2 sequences had their names reversed in the bibliographic pages and FASTA files. This has been corrected.

The only possible mitochondrial P450 from C.elegans has been reexamined to better identify the intron exon boundaries based on similarity to CYP12A sequences of insects. One previously missed exon is added based on an EST sequence and another exon is extended to fill a critical gap. Only about 40% of the sequence is covered by… Read More

Rice P450s have been updated by exhaustively searching the genbank entries for new accession numbers. The sequences have been translated and added to the FASTA P450 rice list. See the rice button on the homepage for more info. There are 192 accession numbers for rice P450s

Two new trees have been made with CYP4 sequences as the main content. These trees illustrate the difficulty of maintaining a sensible nomenclature when families get very large. There are some inconsistencies. The 4D subfamily has been split over time into two different clusters of sequences. Cyp4p should probably be in a separate family. The… Read More

A Tree of 56 Insect P450s The tree with 56 insect P450s includes many new Drosophila sequences. Some are not yet named. This tree is based on an alignment that covers the I- helix to the ends of the sequences, since many are missing the N-terminal. The 4 family sequences are not included here. There… Read More